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Richard A Perugini MD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentSurgery
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
Phone508-334-7656
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentSurgery
    DivisionGeneral Surgery


    Collapse Biography 
    Collapse education and training
    Yale University, New Haven, CT, United StatesBSMolecular Biophysics & Biochem
    University of Connecticut School of Medicine, Farmington, CT, United StatesMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Playter KP, Reddington H, Ballinger ZC, Czerniach DR, Freitas GS, Kelly JJ, Cherng NB, Perugini RA. Evaluation of hemorrhage risk and the volume-outcome relationship following vertical sleeve gastrectomy amidst robotic-assisted surgery adoption. Surg Endosc. 2025 Apr 30. PMID: 40307471.
      Citations:    
    2. Doan TD, Suh L, Wu M, Cherng N, Perugini R. The role of socioeconomic status in resolution of type 2 diabetes mellitus following longitudinal sleeve gastrectomy. Surg Endosc. 2025 01; 39(1):568-576. PMID: 39438310.
      Citations:    
    3. Gandhi SD, Feldman H, Achebe I, Then E, Perugini R, Nasser-Ghodsi N, Rau P, Marya NB. Plug and play: vascular plug therapy for refractory colocutaneous fistula. VideoGIE. 2024 Dec; 9(12):533-535. PMID: 39698405.
      Citations:    
    4. Schneider R, Perugini R, Karthikeyan S, Okereke O, Herscovici DM, Richard A, Doan T, Suh L, Carroll JE. Correction: Perforated peptic ulcer disease in transferred patients is associated with significant increase in length of stay. Surg Endosc. 2024 Mar; 38(3):1662. PMID: 38228838.
      Citations:    Fields:    
    5. Schneider R, Perugini R, Karthikeyan S, Okereke O, Herscovici DM, Richard A, Doan T, Suh L, Carroll JE. Perforated peptic ulcer disease in transferred patients is associated with significant increase in length of stay. Surg Endosc. 2024 03; 38(3):1576-1582. PMID: 38182799.
      Citations:    Fields:    
    6. Mackey EE, Dore FJ, Kelly JF, Crawford AS, Cohen P, Czerniach D, Perugini R, Kelly JJ, Cherng NB. Ligamentum teres cardiopexy for post vertical sleeve gastrectomy gastroesophageal reflux. Surg Endosc. 2023 09; 37(9):7247-7253. PMID: 37407712.
      Citations:    Fields:    Translation:Humans
    7. Chung SK, Bludevich B, Cherng N, Zhang T, Crawford A, Maxfield MW, Whalen G, Uy K, Perugini RA. Paraconduit Hiatal Hernia Following Esophagectomy: Incidence, Risk Factors, Outcomes and Repair. J Surg Res. 2021 12; 268:276-283. PMID: 34392181.
      Citations: 2     Fields:    Translation:Humans
    8. Tencerova M, Aouadi M, Vangala P, Nicoloro SM, Yawe JC, Cohen JL, Shen Y, Garcia-Menendez L, Pedersen DJ, Gallagher-Dorval K, Perugini RA, Gupta OT, Czech MP. Activated Kupffer cells inhibit insulin sensitivity in obese mice. FASEB J. 2015 Jul; 29(7):2959-69. PMID: 25805830.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    9. Kelly JJ, Perugini RA, Wang QL, Czerniach DR, Flahive J, Cohen PA. The presence of Helicobacter pylori is not associated with long-term anastomotic complications in gastric bypass patients. Surg Endosc. 2015 Oct; 29(10):2885-90. PMID: 25552229.
      Citations: 8     Fields:    Translation:HumansCells
    10. English TM, Malkani S, Kinney RL, Omer A, Dziewietin MB, Perugini R. Predicting remission of diabetes after RYGB surgery following intensive management to optimize preoperative glucose control. Obes Surg. 2015 Jan; 25(1):1-6. PMID: 25052254.
      Citations: 8     Fields:    Translation:Humans
    11. Perugini RA. Invited commentary. J Am Coll Surg. 2014 Jun; 218(6):1192-4. PMID: 24840690.
      Citations:    Fields:    Translation:Humans
    12. Perugini RA, Malkani S. Remission of type 2 diabetes mellitus following bariatric surgery: review of mechanisms and presentation of the concept of 'reversibility'. Curr Opin Endocrinol Diabetes Obes. 2011 Apr; 18(2):119-28. PMID: 21522001.
      Citations: 8     Fields:    Translation:HumansCells
    13. Gealekman O, Guseva N, Hartigan C, Apotheker S, Gorgoglione M, Gurav K, Tran KV, Straubhaar J, Nicoloro S, Czech MP, Thompson M, Perugini RA, Corvera S. Depot-specific differences and insufficient subcutaneous adipose tissue angiogenesis in human obesity. Circulation. 2011 Jan 18; 123(2):186-94. PMID: 21200001.
      Citations: 155     Fields:    Translation:Humans
    14. Hardy OT, Perugini RA, Nicoloro SM, Gallagher-Dorval K, Puri V, Straubhaar J, Czech MP. Body mass index-independent inflammation in omental adipose tissue associated with insulin resistance in morbid obesity. Surg Obes Relat Dis. 2011 Jan-Feb; 7(1):60-7. PMID: 20678967.
      Citations: 107     Fields:    Translation:HumansCells
    15. Perugini RA, Li Y, Rosenthal L, Gallagher-Dorval K, Kelly JJ, Czerniach DR. Reduced heart rate variability correlates with insulin resistance but not with measures of obesity in population undergoing laparoscopic Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2010 May-Jun; 6(3):237-41. PMID: 20005785.
      Citations: 12     Fields:    Translation:Humans
    16. Gunabushanam G, Shankar S, Czerniach DR, Kelly JJ, Perugini RA. Small-bowel obstruction after laparoscopic Roux-en-Y gastric bypass surgery. J Comput Assist Tomogr. 2009 May-Jun; 33(3):369-75. PMID: 19478629.
      Citations: 21     Fields:    Translation:Humans
    17. Favuzza J, Friel JC, Kelly JJ, Perugini R, Counihan TC. Benefits of laparoscopic peritoneal lavage for complicated sigmoid diverticulitis. Int J Colorectal Dis. 2009 Jul; 24(7):797-801. PMID: 19165490.
      Citations: 27     Fields:    Translation:Humans
    18. Moore R, Perugini R, Czerniach D, Gallagher-Dorval K, Mason R, Kelly JJ. Early results of conversion of laparoscopic adjustable gastric band to Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2009 Jul-Aug; 5(4):439-43. PMID: 19342311.
      Citations: 15     Fields:    Translation:Humans
    19. Puri V, Ranjit S, Konda S, Nicoloro SM, Straubhaar J, Chawla A, Chouinard M, Lin C, Burkart A, Corvera S, Perugini RA, Czech MP. Cidea is associated with lipid droplets and insulin sensitivity in humans. Proc Natl Acad Sci U S A. 2008 Jun 03; 105(22):7833-8. PMID: 18509062.
      Citations: 158     Fields:    Translation:HumansAnimalsCells
    20. Kaban GK, Novitsky YW, Perugini RA, Haveran L, Czerniach D, Kelly JJ, Litwin DE. Use of laparoscopy in evaluation and treatment of penetrating and blunt abdominal injuries. Surg Innov. 2008 Mar; 15(1):26-31. PMID: 18407927.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    21. Perugini RA, Quarfordt SH, Baker S, Czerniach DR, Litwin DE, Kelly JJ. Metabolic characterization of nondiabetic severely obese patients undergoing Roux-en-Y gastric bypass: preoperative classification predicts the effects of gastric bypass on insulin-glucose homeostasis. J Gastrointest Surg. 2007 Sep; 11(9):1083-90. PMID: 17588192.
      Citations: 6     Fields:    Translation:HumansCells
    22. Dundamadappa SK, Shankar S, Danrad R, Singh A, Vijayaraghavan G, Kim Y, Perugini R. Imaging of brown fat associated with adrenal pheochromocytoma. Acta Radiol. 2007 May; 48(4):468-72. PMID: 17453531.
      Citations: 7     Fields:    Translation:Humans
    23. Puri V, Chakladar A, Virbasius JV, Konda S, Powelka AM, Chouinard M, Hagan GN, Perugini R, Czech MP. RNAi-based gene silencing in primary mouse and human adipose tissues. J Lipid Res. 2007 Feb; 48(2):465-71. PMID: 17093294.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    24. Ma Y, Pagoto SL, Olendzki BC, Hafner AR, Perugini RA, Mason R, Kelly JJ. Predictors of weight status following laparoscopic gastric bypass. Obes Surg. 2006 Sep; 16(9):1227-31. PMID: 16989709.
      Citations: 80     Fields:    Translation:Humans
    25. Novitsky YW, Czerniach DR, Kaban GK, Bergner A, Gallagher KA, Perugini RA, Litwin DE. Immunologic effects of hand-assisted surgery on peritoneal macrophages: comparison to open and standard laparoscopic approaches. Surgery. 2006 Jan; 139(1):39-45. PMID: 16364716.
      Citations: 7     Fields:    Translation:AnimalsCells
    26. Kaban GK, Czerniach DR, Cohen R, Novitsky YW, Yood SM, Perugini RA, Kelly JJ, Litwin DE. Hand-assisted laparoscopic splenectomy in the setting of splenomegaly. Surg Endosc. 2004 Sep; 18(9):1340-3. PMID: 15803233.
      Citations: 15     Fields:    Translation:Humans
    27. Kaban GK, Czerniach DR, Perugini RA, Novitsky YW, Kelly JJ, Litwin DE. Use of a laparoscopic hand-assist device for accessory splenectomy. Surg Endosc. 2004 Jun; 18(6):1001. PMID: 15026918.
      Citations: 1     Fields:    Translation:Humans
    28. Perugini RA, Mason R, Czerniach DR, Novitsky YW, Baker S, Litwin DE, Kelly JJ. Predictors of complication and suboptimal weight loss after laparoscopic Roux-en-Y gastric bypass: a series of 188 patients. Arch Surg. 2003 May; 138(5):541-5; discussion 545-6. PMID: 12742960.
      Citations: 58     Fields:    Translation:Humans
    29. Novitsky YW, Czerniach DR, Kercher KW, Perugini RA, Kelly JJ, Litwin DE. Feasibility of laparoscopic adrenalectomy for large adrenal masses. Surg Laparosc Endosc Percutan Tech. 2003 Apr; 13(2):106-10. PMID: 12709616.
      Citations: 26     Fields:    Translation:Humans
    30. Shah SA, Potter MW, Ricciardi R, Perugini RA, Callery MP. FRAP-p70s6K signaling is required for pancreatic cancer cell proliferation. J Surg Res. 2001 May 15; 97(2):123-30. PMID: 11341787.
      Citations: 10     Fields:    Translation:HumansCells
    31. Vittimberga FJ, Nolan B, Perugini RA, Spector L, Callery MP. Laparoscopic surgery and Kupffer cell activation. Surg Endosc. 2000 Dec; 14(12):1171-6. PMID: 11148792.
      Citations: 4     Fields:    Translation:AnimalsCells
    32. Ricciardi R, Kim RD, McDade TP, Perugini RA, Veal TM, Quarfordt SH, Callery MP, Chari RS, Meyers WC. NFkappaB expression during cold ischemia correlates with postreperfusion graft function. J Surg Res. 2000 Sep; 93(1):35-40. PMID: 10945941.
      Citations: 2     Fields:    Translation:Animals
    33. Perugini RA, McDade TP, Vittimberga FJ, Callery MP. Pancreatic cancer cell proliferation is phosphatidylinositol 3-kinase dependent. J Surg Res. 2000 May 01; 90(1):39-44. PMID: 10781373.
      Citations: 35     Fields:    Translation:HumansCells
    34. Perugini RA, McDade TP, Vittimberga FJ, Duffy AJ, Callery MP. Sodium salicylate inhibits proliferation and induces G1 cell cycle arrest in human pancreatic cancer cell lines. J Gastrointest Surg. 2000 Jan-Feb; 4(1):24-32, discussion 32-3. PMID: 10631359.
      Citations: 11     Fields:    Translation:HumansCells
    35. McDade TP, Perugini RA, Vittimberga FJ, Callery MP. Ubiquitin-proteasome inhibition enhances apoptosis of human pancreatic cancer cells. Surgery. 1999 Aug; 126(2):371-7. PMID: 10455908.
      Citations: 11     Fields:    Translation:HumansCells
    36. Vittimberga FJ, McDade TP, Perugini RA, Callery MP. Sodium salicylate inhibits macrophage TNF-alpha production and alters MAPK activation. J Surg Res. 1999 Jun 15; 84(2):143-9. PMID: 10357911.
      Citations: 9     Fields:    Translation:AnimalsCells
    37. McDade TP, Perugini RA, Vittimberga FJ, Carrigan RC, Callery MP. Salicylates inhibit NF-kappaB activation and enhance TNF-alpha-induced apoptosis in human pancreatic cancer cells. J Surg Res. 1999 May 01; 83(1):56-61. PMID: 10210643.
      Citations: 20     Fields:    Translation:HumansCells
    38. Vittimberga FJ, Foley DP, Perugini RA, McDade TP, Callery MP. Endotoxin fails to stimulate inositol triphosphate production in macrophages. Int J Surg Investig. 1999; 1(3):229-35. PMID: 11341611.
      Citations: 1     Fields:    Translation:Cells
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