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This is a "connection" page, showing publications co-authored by John Mordes and Dale Greiner.
John Mordes
Connection Strength
3.763
Dale Greiner
  1. Mordes JP, Bortell R, Blankenhorn EP, Rossini AA, Greiner DL. Rat models of type 1 diabetes: genetics, environment, and autoimmunity. ILAR J. 2004; 45(3):278-91.
    View in: PubMed
    Score: 0.234
  2. Greiner DL, Rossini AA, Mordes JP. Translating data from animal models into methods for preventing human autoimmune diabetes mellitus: caveat emptor and primum non nocere. Clin Immunol. 2001 Aug; 100(2):134-43.
    View in: PubMed
    Score: 0.198
  3. Liu Z, Cort L, Eberwine R, Herrmann T, Leif JH, Greiner DL, Yahalom B, Blankenhorn EP, Mordes JP. Prevention of type 1 diabetes in the rat with an allele-specific anti-T-cell receptor antibody: V?13 as a therapeutic target and biomarker. Diabetes. 2012 May; 61(5):1160-8.
    View in: PubMed
    Score: 0.103
  4. Tirabassi RS, Guberski DL, Blankenhorn EP, Leif JH, Woda BA, Liu Z, Winans D, Greiner DL, Mordes JP. Infection with viruses from several families triggers autoimmune diabetes in LEW*1WR1 rats: prevention of diabetes by maternal immunization. Diabetes. 2010 Jan; 59(1):110-8.
    View in: PubMed
    Score: 0.087
  5. Blankenhorn EP, Cort L, Greiner DL, Guberski DL, Mordes JP. Virus-induced autoimmune diabetes in the LEW.1WR1 rat requires Iddm14 and a genetic locus proximal to the major histocompatibility complex. Diabetes. 2009 Dec; 58(12):2930-8.
    View in: PubMed
    Score: 0.087
  6. Mordes JP, Cort L, Norowski E, Leif J, Fuller JM, Lernmark A, Greiner DL, Blankenhorn EP. Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus. Mamm Genome. 2009 Mar; 20(3):162-9.
    View in: PubMed
    Score: 0.084
  7. Thornley TB, Phillips NE, Beaudette-Zlatanova BC, Markees TG, Bahl K, Brehm MA, Shultz LD, Kurt-Jones EA, Mordes JP, Welsh RM, Rossini AA, Greiner DL. Type 1 IFN mediates cross-talk between innate and adaptive immunity that abrogates transplantation tolerance. J Immunol. 2007 Nov 15; 179(10):6620-9.
    View in: PubMed
    Score: 0.077
  8. Yamazaki M, Pearson T, Brehm MA, Miller DM, Mangada JA, Markees TG, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Different mechanisms control peripheral and central tolerance in hematopoietic chimeric mice. Am J Transplant. 2007 Jul; 7(7):1710-21.
    View in: PubMed
    Score: 0.075
  9. King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, Atkinson M, Wasserfall C, Herold K, Mordes JP, Rossini AA, Greiner DL. Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity. Ann N Y Acad Sci. 2007 Apr; 1103:90-3.
    View in: PubMed
    Score: 0.073
  10. Blankenhorn EP, Descipio C, Rodemich L, Cort L, Leif JH, Greiner DL, Mordes JP. Refinement of the Iddm4 diabetes susceptibility locus reveals TCRVbeta4 as a candidate gene. Ann N Y Acad Sci. 2007 Apr; 1103:128-31.
    View in: PubMed
    Score: 0.073
  11. Thornley TB, Brehm MA, Markees TG, Shultz LD, Mordes JP, Welsh RM, Rossini AA, Greiner DL. TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts. J Immunol. 2006 Feb 01; 176(3):1561-70.
    View in: PubMed
    Score: 0.068
  12. Mordes JP, Guberski DL, Leif JH, Woda BA, Flanagan JF, Greiner DL, Kislauskis EH, Tirabassi RS. LEW.1WR1 rats develop autoimmune diabetes spontaneously and in response to environmental perturbation. Diabetes. 2005 Sep; 54(9):2727-33.
    View in: PubMed
    Score: 0.066
  13. Blankenhorn EP, Rodemich L, Martin-Fernandez C, Leif J, Greiner DL, Mordes JP. The rat diabetes susceptibility locus Iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection. Diabetes. 2005 Apr; 54(4):1233-7.
    View in: PubMed
    Score: 0.064
  14. Gordon EJ, Wicker LS, Peterson LB, Serreze DV, Markees TG, Shultz LD, Rossini AA, Greiner DL, Mordes JP. Autoimmune diabetes and resistance to xenograft transplantation tolerance in NOD mice. Diabetes. 2005 Jan; 54(1):107-15.
    View in: PubMed
    Score: 0.063
  15. Banuelos SJ, Markees TG, Phillips NE, Appel MC, Cuthbert A, Leif J, Mordes JP, Shultz LD, Rossini AA, Greiner DL. Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms. Transplantation. 2004 Sep 15; 78(5):660-7.
    View in: PubMed
    Score: 0.062
  16. Pearson T, Weiser P, Markees TG, Serreze DV, Wicker LS, Peterson LB, Cumisky AM, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Islet allograft survival induced by costimulation blockade in NOD mice is controlled by allelic variants of Idd3. Diabetes. 2004 Aug; 53(8):1972-8.
    View in: PubMed
    Score: 0.061
  17. Pearson T, Markees TG, Serreze DV, Pierce MA, Wicker LS, Peterson LB, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Islet cell autoimmunity and transplantation tolerance: two distinct mechanisms? Ann N Y Acad Sci. 2003 Nov; 1005:148-56.
    View in: PubMed
    Score: 0.058
  18. Seung E, Mordes JP, Rossini AA, Greiner DL. Hematopoietic chimerism and central tolerance created by peripheral-tolerance induction without myeloablative conditioning. J Clin Invest. 2003 Sep; 112(5):795-808.
    View in: PubMed
    Score: 0.057
  19. Pearson T, Markees TG, Serreze DV, Pierce MA, Wicker LS, Peterson LB, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Genetic separation of the transplantation tolerance and autoimmune phenotypes in NOD mice. Rev Endocr Metab Disord. 2003 Sep; 4(3):255-61.
    View in: PubMed
    Score: 0.057
  20. Pearson T, Markees TG, Serreze DV, Pierce MA, Marron MP, Wicker LS, Peterson LB, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice. J Immunol. 2003 Jul 01; 171(1):185-95.
    View in: PubMed
    Score: 0.057
  21. Pearson T, Markees TG, Wicker LS, Serreze DV, Peterson LB, Mordes JP, Rossini AA, Greiner DL. NOD congenic mice genetically protected from autoimmune diabetes remain resistant to transplantation tolerance induction. Diabetes. 2003 Feb; 52(2):321-6.
    View in: PubMed
    Score: 0.055
  22. Whalen BJ, Marounek J, Mordes JP, Rossini AA, Greiner DL. Type 1 cytokines polarize thymocytes during T cell development in adult thymus organ cultures. J Autoimmun. 2003 Feb; 20(1):27-42.
    View in: PubMed
    Score: 0.055
  23. Mordes JP, Leif J, Novak S, DeScipio C, Greiner DL, Blankenhorn EP. The iddm4 locus segregates with diabetes susceptibility in congenic WF.iddm4 rats. Diabetes. 2002 Nov; 51(11):3254-62.
    View in: PubMed
    Score: 0.054
  24. Forman D, Welsh RM, Markees TG, Woda BA, Mordes JP, Rossini AA, Greiner DL. Viral abrogation of stem cell transplantation tolerance causes graft rejection and host death by different mechanisms. J Immunol. 2002 Jun 15; 168(12):6047-56.
    View in: PubMed
    Score: 0.053
  25. Bortel R, Waite DJ, Whalen BJ, Todd D, Leif JH, Lesma E, Moss J, Mordes JP, Rossini AA, Greiner DL. Levels of Art2+ cells but not soluble Art2 protein correlate with expression of autoimmune diabetes in the BB rat. Autoimmunity. 2001 May; 33(3):199-211.
    View in: PubMed
    Score: 0.049
  26. Gordon EJ, Woda BA, Shultz LD, Rossini AA, Greiner DL, Mordes JP. Rat xenograft survival in mice treated with donor-specific transfusion and anti-CD154 antibody is enhanced by elimination of host CD4+ cells. Transplantation. 2001 Jan 27; 71(2):319-27.
    View in: PubMed
    Score: 0.048
  27. Seung E, Iwakoshi N, Woda BA, Markees TG, Mordes JP, Rossini AA, Greiner DL. Allogeneic hematopoietic chimerism in mice treated with sublethal myeloablation and anti-CD154 antibody: absence of graft-versus-host disease, induction of skin allograft tolerance, and prevention of recurrent autoimmunity in islet-allografted NOD/Lt mice. Blood. 2000 Mar 15; 95(6):2175-82.
    View in: PubMed
    Score: 0.045
  28. Iwakoshi NN, Mordes JP, Markees TG, Phillips NE, Rossini AA, Greiner DL. Treatment of allograft recipients with donor-specific transfusion and anti-CD154 antibody leads to deletion of alloreactive CD8+ T cells and prolonged graft survival in a CTLA4-dependent manner. J Immunol. 2000 Jan 01; 164(1):512-21.
    View in: PubMed
    Score: 0.044
  29. Whalen BJ, Love LC, Mordes JP, Rossini AA, Greiner DL. Intravital dye-labeled diabetogenic rat T cells retain dye, home to the pancreas, and induce diabetes. Transplant Proc. 1999 May; 31(3):1611-4.
    View in: PubMed
    Score: 0.042
  30. Whalen BJ, Weiser P, Marounek J, Rossini AA, Mordes JP, Greiner DL. Recapitulation of normal and abnormal BioBreeding rat T cell development in adult thymus organ culture. J Immunol. 1999 Apr 01; 162(7):4003-12.
    View in: PubMed
    Score: 0.042
  31. Bortell R, Kanaitsuka T, Stevens LA, Moss J, Mordes JP, Rossini AA, Greiner DL. The RT6 (Art2) family of ADP-ribosyltransferases in rat and mouse. Mol Cell Biochem. 1999 Mar; 193(1-2):61-8.
    View in: PubMed
    Score: 0.042
  32. Rossini AA, Mordes JP, Markees TG, Phillips NE, Gordon EJ, Greiner DL. Induction of islet transplantation tolerance using donor specific transfusion and anti-CD154 monoclonal antibody. Transplant Proc. 1999 Feb-Mar; 31(1-2):629-32.
    View in: PubMed
    Score: 0.042
  33. Martin AM, Blankenhorn EP, Maxson MN, Zhao M, Leif J, Mordes JP, Greiner DL. Non-major histocompatibility complex-linked diabetes susceptibility loci on chromosomes 4 and 13 in a backcross of the DP-BB/Wor rat to the WF rat. Diabetes. 1999 Jan; 48(1):50-8.
    View in: PubMed
    Score: 0.041
  34. Rossini AA, Greiner DL, Mordes JP. Induction of immunologic tolerance for transplantation. Physiol Rev. 1999 Jan; 79(1):99-141.
    View in: PubMed
    Score: 0.041
  35. Iwakoshi NN, Greiner DL, Rossini AA, Mordes JP. Diabetes prone BB rats are severely deficient in natural killer T cells. Autoimmunity. 1999; 31(1):1-14.
    View in: PubMed
    Score: 0.041
  36. Gordon EJ, Markees TG, Phillips NE, Noelle RJ, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Prolonged survival of rat islet and skin xenografts in mice treated with donor splenocytes and anti-CD154 monoclonal antibody. Diabetes. 1998 Aug; 47(8):1199-206.
    View in: PubMed
    Score: 0.040
  37. Iwakoshi NN, Goldschneider I, Tausche F, Mordes JP, Rossini AA, Greiner DL. High frequency apoptosis of recent thymic emigrants in the liver of lymphopenic diabetes-prone BioBreeding rats. J Immunol. 1998 Jun 15; 160(12):5838-50.
    View in: PubMed
    Score: 0.040
  38. Whalen BJ, Doukas J, Mordes JP, Rossini AA, Greiner DL. Induction of insulin-dependent diabetes mellitus in PVG.RT1u rats. Transplant Proc. 1997 May; 29(3):1684-5.
    View in: PubMed
    Score: 0.037
  39. Greiner DL, Malkani S, Kanaitsuka T, Bortell R, Doukas J, Rigby M, Whalen B, Stevens LA, Moss J, Mordes JP, Rossini AA. The T cell marker RT6 in a rat model of autoimmune diabetes. Adv Exp Med Biol. 1997; 419:209-16.
    View in: PubMed
    Score: 0.036
  40. Mordes JP, Bortell R, Doukas J, Rigby M, Whalen B, Zipris D, Greiner DL, Rossini AA. The BB/Wor rat and the balance hypothesis of autoimmunity. Diabetes Metab Rev. 1996 Jul; 12(2):103-9.
    View in: PubMed
    Score: 0.035
  41. Waite DJ, Appel MC, Handler ES, Mordes JP, Rossini AA, Greiner DL. Ontogeny and immunohistochemical localization of thymus-dependent and thymus-independent RT6+ cells in the rat. Am J Pathol. 1996 Jun; 148(6):2043-56.
    View in: PubMed
    Score: 0.035
  42. Mordes JP, Schirf B, Roipko D, Greiner DL, Weiner H, Nelson P, Rossini AA. Oral insulin does not prevent insulin-dependent diabetes mellitus in BB rats. Ann N Y Acad Sci. 1996 Feb 13; 778:418-21.
    View in: PubMed
    Score: 0.034
  43. Rossini AA, Parker DC, Phillips NE, Durie FH, Noelle RJ, Mordes JP, Greiner DL. Induction of immunological tolerance to islet allografts. Cell Transplant. 1996 Jan-Feb; 5(1):49-52.
    View in: PubMed
    Score: 0.034
  44. Whalen BJ, Rossini AA, Mordes JP, Greiner DL. DR-BB rat thymus contains thymocyte populations predisposed to autoreactivity. Diabetes. 1995 Aug; 44(8):963-7.
    View in: PubMed
    Score: 0.033
  45. Rossini AA, Handler ES, Mordes JP, Greiner DL. Human autoimmune diabetes mellitus: lessons from BB rats and NOD mice--Caveat emptor. Clin Immunol Immunopathol. 1995 Jan; 74(1):2-9.
    View in: PubMed
    Score: 0.031
  46. Doukas J, Mordes JP, Swymer C, Niedzwiecki D, Mason R, Rozing J, Rossini AA, Greiner DL. Thymic epithelial defects and predisposition to autoimmune disease in BB rats. Am J Pathol. 1994 Dec; 145(6):1517-25.
    View in: PubMed
    Score: 0.031
  47. Waite DJ, Handler ES, Mordes JP, Rossini AA, Greiner DL. The RT6 rat lymphocyte alloantigen circulates in soluble form. Cell Immunol. 1993 Nov; 152(1):82-95.
    View in: PubMed
    Score: 0.029
  48. Greiner DL, Shultz LD, Rossini AA, Mordes JP, Handler ES, Rajan TV. Recapitulation of normal and abnormal BB rat immune system development in scid mouse/rat lymphohemopoietic chimeras. J Clin Invest. 1991 Aug; 88(2):717-9.
    View in: PubMed
    Score: 0.025
  49. Rossini AA, Handler ES, Greiner DL, Mordes JP. Insulin dependent diabetes mellitus hypothesis of autoimmunity. Autoimmunity. 1991; 8(3):221-35.
    View in: PubMed
    Score: 0.024
  50. Kruger AJ, Yang C, Tam SW, Hinerfeld D, Evans JE, Green KM, Leszyk J, Yang K, Guberski DL, Mordes JP, Greiner DL, Rossini AA, Bortell R. Haptoglobin as an early serum biomarker of virus-induced autoimmune type 1 diabetes in biobreeding diabetes resistant and LEW1.WR1 rats. Exp Biol Med (Maywood). 2010 Nov; 235(11):1328-37.
    View in: PubMed
    Score: 0.024
  51. Jurczyk A, Pino SC, O'Sullivan-Murphy B, Addorio M, Lidstone EA, Diiorio P, Lipson KL, Standley C, Fogarty K, Lifshitz L, Urano F, Mordes JP, Greiner DL, Rossini AA, Bortell R. A novel role for the centrosomal protein, pericentrin, in regulation of insulin secretory vesicle docking in mouse pancreatic beta-cells. PLoS One. 2010 Jul 27; 5(7):e11812.
    View in: PubMed
    Score: 0.023
  52. Pino SC, O'Sullivan-Murphy B, Lidstone EA, Yang C, Lipson KL, Jurczyk A, diIorio P, Brehm MA, Mordes JP, Greiner DL, Rossini AA, Bortell R. CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells. PLoS One. 2009; 4(5):e5468.
    View in: PubMed
    Score: 0.021
  53. Chopra P, Diiorio P, Pino SC, Wilson SB, Phillips NE, Mordes JP, Rossini AA, Greiner DL, Shultz LD, Bortell R. Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat. In Vivo. 2009 Mar-Apr; 23(2):195-201.
    View in: PubMed
    Score: 0.021
  54. Bishop KD, Harris JE, Mordes JP, Greiner DL, Rossini AA, Czech MP, Phillips NE. Depletion of the programmed death-1 receptor completely reverses established clonal anergy in CD4(+) T lymphocytes via an interleukin-2-dependent mechanism. Cell Immunol. 2009; 256(1-2):86-91.
    View in: PubMed
    Score: 0.021
  55. Rossini AA, Mordes JP, Greiner DL. The pathogenesis of autoimmune diabetes mellitus. Curr Opin Immunol. 1989-1990 Apr; 2(4):598-603.
    View in: PubMed
    Score: 0.021
  56. Pino SC, O'Sullivan-Murphy B, Lidstone EA, Thornley TB, Jurczyk A, Urano F, Greiner DL, Mordes JP, Rossini AA, Bortell R. Protein kinase C signaling during T cell activation induces the endoplasmic reticulum stress response. Cell Stress Chaperones. 2008 Dec; 13(4):421-34.
    View in: PubMed
    Score: 0.020
  57. Greiner DL, Angelillo M, Mordes JP, Handler ES, Mojcik CF, Nakamura N, Rossini AA. Regulatory T cell control of autoimmune destruction of beta cells in the BB rat. Adv Exp Med Biol. 1988; 246:379-85.
    View in: PubMed
    Score: 0.019
  58. Greiner DL, Mordes JP, Handler ES, Angelillo M, Nakamura N, Rossini AA. Depletion of RT6.1+ T lymphocytes induces diabetes in resistant biobreeding/Worcester (BB/W) rats. J Exp Med. 1987 Aug 01; 166(2):461-75.
    View in: PubMed
    Score: 0.019
  59. Greiner DL, Mordes JP, Handler ES, Nakamura N, Angelillo M, Rossini AA. Prothymocyte development in diabetes-prone BB rats: description of a defect that predisposes to immune abnormalities. Transplant Proc. 1987 Feb; 19(1 Pt 2):976-8.
    View in: PubMed
    Score: 0.018
  60. Zipris D, Lien E, Nair A, Xie JX, Greiner DL, Mordes JP, Rossini AA. TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat. J Immunol. 2007 Jan 15; 178(2):693-701.
    View in: PubMed
    Score: 0.018
  61. Mordes JP, Gallina DL, Handler ES, Greiner DL, Nakamura N, Pelletier A, Rossini AA. Transfusions enriched for W3/25+ helper/inducer T lymphocytes prevent spontaneous diabetes in the BB/W rat. Diabetologia. 1987 Jan; 30(1):22-6.
    View in: PubMed
    Score: 0.018
  62. Hillebrands JL, Whalen B, Visser JT, Koning J, Bishop KD, Leif J, Rozing J, Mordes JP, Greiner DL, Rossini AA. A regulatory CD4+ T cell subset in the BB rat model of autoimmune diabetes expresses neither CD25 nor Foxp3. J Immunol. 2006 Dec 01; 177(11):7820-32.
    View in: PubMed
    Score: 0.018
  63. Phillips NE, Greiner DL, Mordes JP, Rossini AA. Costimulatory blockade induces hyporesponsiveness in T cells that recognize alloantigen via indirect antigen presentation. Transplantation. 2006 Oct 27; 82(8):1085-92.
    View in: PubMed
    Score: 0.018
  64. Morrison AR, Moss J, Stevens LA, Evans JE, Farrell C, Merithew E, Lambright DG, Greiner DL, Mordes JP, Rossini AA, Bortell R. ART2, a T cell surface mono-ADP-ribosyltransferase, generates extracellular poly(ADP-ribose). J Biol Chem. 2006 Nov 03; 281(44):33363-72.
    View in: PubMed
    Score: 0.018
  65. Beaudette-Zlatanova BC, Whalen B, Zipris D, Yagita H, Rozing J, Groen H, Benjamin CD, Hunig T, Drexhage HA, Ansari MJ, Leif J, Mordes JP, Greiner DL, Sayegh MH, Rossini AA. Costimulation and autoimmune diabetes in BB rats. Am J Transplant. 2006 May; 6(5 Pt 1):894-902.
    View in: PubMed
    Score: 0.017
  66. Masaki H, Appel MC, Leahy L, Leif J, Paquin L, Shultz LD, Mordes JP, Greiner DL, Rossini AA. Anti-mouse CD154 antibody treatment facilitates generation of mixed xenogeneic rat hematopoietic chimerism, prevents wasting disease and prolongs xenograft survival in mice. Xenotransplantation. 2006 May; 13(3):224-32.
    View in: PubMed
    Score: 0.017
  67. Greiner DL, Handler ES, Nakano K, Mordes JP, Rossini AA. Absence of the RT-6 T cell subset in diabetes-prone BB/W rats. J Immunol. 1986 Jan; 136(1):148-51.
    View in: PubMed
    Score: 0.017
  68. Zipris D, Lien E, Xie JX, Greiner DL, Mordes JP, Rossini AA. TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats. J Immunol. 2005 Jan 01; 174(1):131-42.
    View in: PubMed
    Score: 0.016
  69. Harris JE, Bishop KD, Phillips NE, Mordes JP, Greiner DL, Rossini AA, Czech MP. Early growth response gene-2, a zinc-finger transcription factor, is required for full induction of clonal anergy in CD4+ T cells. J Immunol. 2004 Dec 15; 173(12):7331-8.
    View in: PubMed
    Score: 0.016
  70. Markees TG, Pearson T, Cuthbert A, Pearson AL, Shultz LD, Leif J, Phillips NE, Mordes JP, Greiner DL, Rossini AA. Evaluation of donor-specific transfusion sources: unique failure of bone marrow cells to induce prolonged skin allograft survival with anti-CD154 monoclonal antibody. Transplantation. 2004 Dec 15; 78(11):1601-8.
    View in: PubMed
    Score: 0.016
  71. Appel MC, Banuelos SJ, Greiner DL, Shultz LD, Mordes JP, Rossini AA. Prolonged survival of neonatal porcine islet xenografts in mice treated with a donor-specific transfusion and anti-CD154 antibody. Transplantation. 2004 May 15; 77(9):1341-9.
    View in: PubMed
    Score: 0.015
  72. Todd DJ, Forsberg EM, Greiner DL, Mordes JP, Rossini AA, Bortell R. Deficiencies in gut NK cell number and function precede diabetes onset in BB rats. J Immunol. 2004 May 01; 172(9):5356-62.
    View in: PubMed
    Score: 0.015
  73. Hornum L, DeScipio C, Markholst H, Troutman SA, Novak S, Leif J, Greiner D, Mordes JP, Blankenhorn EP. Comparative mapping of rat Iddm4 to segments on HSA7 and MMU6. Mamm Genome. 2004 Jan; 15(1):53-61.
    View in: PubMed
    Score: 0.015
  74. Turgeon NA, Banuelos SJ, Shultz LD, Lyons BL, Iwakoshi N, Greiner DL, Mordes JP, Rossini AA, Appel MC. Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice. Exp Biol Med (Maywood). 2003 Oct; 228(9):1096-104.
    View in: PubMed
    Score: 0.014
  75. Pandarpurkar M, Wilson-Fritch L, Corvera S, Markholst H, Hornum L, Greiner DL, Mordes JP, Rossini AA, Bortell R. Ian4 is required for mitochondrial integrity and T cell survival. Proc Natl Acad Sci U S A. 2003 Sep 02; 100(18):10382-7.
    View in: PubMed
    Score: 0.014
  76. Seung E, Mordes JP, Greiner DL, Rossini AA. Induction of tolerance for islet transplantation for type 1 diabetes. Curr Diab Rep. 2003 Aug; 3(4):329-35.
    View in: PubMed
    Score: 0.014
  77. Zipris D, Hillebrands JL, Welsh RM, Rozing J, Xie JX, Mordes JP, Greiner DL, Rossini AA. Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations. J Immunol. 2003 Apr 01; 170(7):3592-602.
    View in: PubMed
    Score: 0.014
  78. Phillips NE, Markees TG, Mordes JP, Greiner DL, Rossini AA. Blockade of CD40-mediated signaling is sufficient for inducing islet but not skin transplantation tolerance. J Immunol. 2003 Mar 15; 170(6):3015-23.
    View in: PubMed
    Score: 0.014
  79. Waegell W, Babineau M, Hart M, Dixon K, McRae B, Wallace C, Leach M, Ratnofsky S, Belanger A, Hirst G, Rossini A, Appel M, Mordes J, Greiner D, Banerjee S. A420983, a novel, small molecule inhibitor of LCK prevents allograft rejection. Transplant Proc. 2002 Aug; 34(5):1411-7.
    View in: PubMed
    Score: 0.013
  80. Iwakoshi NN, Markees TG, Turgeon N, Thornley T, Cuthbert A, Leif J, Phillips NE, Mordes JP, Greiner DL, Rossini AA. Skin allograft maintenance in a new synchimeric model system of tolerance. J Immunol. 2001 Dec 01; 167(11):6623-30.
    View in: PubMed
    Score: 0.013
  81. Rossini AA, Mordes JP, Greiner DL, Stoff JS. Islet cell transplantation tolerance. Transplantation. 2001 Oct 27; 72(8 Suppl):S43-6.
    View in: PubMed
    Score: 0.013
  82. Todd DJ, Greiner DL, Rossini AA, Mordes JP, Bortell R. An atypical population of NK cells that spontaneously secrete IFN-gamma and IL-4 is present in the intraepithelial lymphoid compartment of the rat. J Immunol. 2001 Oct 01; 167(7):3600-9.
    View in: PubMed
    Score: 0.013
  83. Bortell R, Moss J, McKenna RC, Rigby MR, Niedzwiecki D, Stevens LA, Patton WA, Mordes JP, Greiner DL, Rossini AA. Nicotinamide adenine dinucleotide (NAD) and its metabolites inhibit T lymphocyte proliferation: role of cell surface NAD glycohydrolase and pyrophosphatase activities. J Immunol. 2001 Aug 15; 167(4):2049-59.
    View in: PubMed
    Score: 0.012
  84. Whalen BJ, Marounek J, Weiser P, Appel MC, Greiner DL, Mordes JP, Rossini AA. BB rat thymocytes cultured in the presence of islets lose their ability to transfer autoimmune diabetes. Diabetes. 2001 May; 50(5):972-9.
    View in: PubMed
    Score: 0.012
  85. Zipris D, Leif J, Deluca D, Lin MY, Mordes JP, Rossini AA, Greiner DL, Whalen BJ. Fetal thymi from diabetes-prone but not diabetes-resistant BB/Wor rats fail to generate mature ART2+ T-cells in organ culture. Cell Mol Biol (Noisy-le-grand). 2001 Feb; 47(1):65-74.
    View in: PubMed
    Score: 0.012
  86. Turgeon NA, Iwakoshi NN, Phillips NE, Meyers WC, Welsh RM, Greiner DL, Mordes JP, Rossini AA. Viral infection abrogates CD8(+) T-cell deletion induced by costimulation blockade. J Surg Res. 2000 Sep; 93(1):63-9.
    View in: PubMed
    Score: 0.012
  87. Welsh RM, Markees TG, Woda BA, Daniels KA, Brehm MA, Mordes JP, Greiner DL, Rossini AA. Virus-induced abrogation of transplantation tolerance induced by donor-specific transfusion and anti-CD154 antibody. J Virol. 2000 Mar; 74(5):2210-8.
    View in: PubMed
    Score: 0.011
  88. Martin AM, Maxson MN, Leif J, Mordes JP, Greiner DL, Blankenhorn EP. Diabetes-prone and diabetes-resistant BB rats share a common major diabetes susceptibility locus, iddm4: additional evidence for a "universal autoimmunity locus" on rat chromosome 4. Diabetes. 1999 Nov; 48(11):2138-44.
    View in: PubMed
    Score: 0.011
  89. Markees TG, Serreze DV, Phillips NE, Sorli CH, Gordon EJ, Shultz LD, Noelle RJ, Woda BA, Greiner DL, Mordes JP, Rossini AA. NOD mice have a generalized defect in their response to transplantation tolerance induction. Diabetes. 1999 May; 48(5):967-74.
    View in: PubMed
    Score: 0.011
  90. Todd D, Singh AJ, Greiner DL, Mordes JP, Rossini AA, Bortell R. A new isolation method for rat intraepithelial lymphocytes. J Immunol Methods. 1999 Apr 22; 224(1-2):111-27.
    View in: PubMed
    Score: 0.011
  91. Zheng XX, Markees TG, Hancock WW, Li Y, Greiner DL, Li XC, Mordes JP, Sayegh MH, Rossini AA, Strom TB. CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal antibody treatment. J Immunol. 1999 Apr 15; 162(8):4983-90.
    View in: PubMed
    Score: 0.011
  92. Markees TG, Phillips NE, Gordon EJ, Noelle RJ, Maliszewski C, Mordes JP, Greiner DL, Rossini AA. Prolonged skin allograft survival in mice treated with Flt3-ligand-induced dendritic cells and anti-CD154 monoclonal antibody. Transplant Proc. 1999 Feb-Mar; 31(1-2):884-5.
    View in: PubMed
    Score: 0.010
  93. Lesma E, Moss J, Brewer HB, Bortell R, Greiner D, Mordes J, Rossini AA. Characterization of high density lipoprotein-bound and soluble RT6 released following administration of anti-RT6.1 monoclonal antibody. J Immunol. 1998 Aug 01; 161(3):1212-9.
    View in: PubMed
    Score: 0.010
  94. Markees T, Phillips N, Gordon E, Noelle RJ, Mordes JP, Greiner DL, Rossini AA. Improved skin allograft tolerance induced by treatment with donor splenocytes and an extended course of anti-CD154 monoclonal antibody. Transplant Proc. 1998 Aug; 30(5):2444-6.
    View in: PubMed
    Score: 0.010
  95. Markees TG, Phillips NE, Gordon EJ, Noelle RJ, Shultz LD, Mordes JP, Greiner DL, Rossini AA. Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4. J Clin Invest. 1998 Jun 01; 101(11):2446-55.
    View in: PubMed
    Score: 0.010
  96. Kanaitsuka T, Bortell R, Stevens LA, Moss J, Sardinha D, Rajan TV, Zipris D, Mordes JP, Greiner DL, Rossini AA. Expression in BALB/c and C57BL/6 mice of Rt6-1 and Rt6-2 ADP-ribosyltransferases that differ in enzymatic activity: C57BL/6 Rt6-1 is a natural transferase knockout. J Immunol. 1997 Sep 15; 159(6):2741-9.
    View in: PubMed
    Score: 0.009
  97. Markees TG, Phillips NE, Noelle RJ, Shultz LD, Mordes JP, Greiner DL, Rossini AA. Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand. Transplantation. 1997 Jul 27; 64(2):329-35.
    View in: PubMed
    Score: 0.009
  98. Malkani S, Nompleggi D, Hansen JW, Greiner DL, Mordes JP, Rossini AA. Dietary cow's milk protein does not alter the frequency of diabetes in the BB rat. Diabetes. 1997 Jul; 46(7):1133-40.
    View in: PubMed
    Score: 0.009
  99. Moss J, Stevens LA, Cavanaugh E, Okazaki IJ, Bortell R, Kanaitsuka T, Mordes JP, Greiner DL, Rossini AA. Characterization of mouse Rt6.1 NAD:arginine ADP-ribosyltransferase. J Biol Chem. 1997 Feb 14; 272(7):4342-6.
    View in: PubMed
    Score: 0.009
  100. Bortell R, Rigby M, Stevens L, Moss J, Kanaitsuka T, Mordes J, Greiner D, Rossini A. Mouse RT6 locus 1 and rat RT6.2 are NAD+. Arginine ADP-ribosyltransferases with auto-ADP-ribosylation activity. Adv Exp Med Biol. 1997; 419:169-73.
    View in: PubMed
    Score: 0.009
  101. Rigby MR, Bortell R, Greiner DL, Czech MP, Klarlund JK, Mordes JP, Rossini AA. The rat T-cell surface protein RT6 is associated with src family tyrosine kinases and generates an activation signal. Diabetes. 1996 Oct; 45(10):1419-26.
    View in: PubMed
    Score: 0.009
  102. Rigby MR, Bortell R, Stevens LA, Moss J, Kanaitsuka T, Shigeta H, Mordes JP, Greiner DL, Rossini AA. Rat RT6.2 and mouse Rt6 locus 1 are NAD+: arginine ADP ribosyltransferases with auto-ADP ribosylation activity. J Immunol. 1996 Jun 01; 156(11):4259-65.
    View in: PubMed
    Score: 0.009
  103. Markees TG, Appel MC, Noelle RJ, Mordes JP, Greiner DL, Rossini AA. Tolerance to islet xenografts induced by dual manipulation of antigen presentation and co-stimulation. Transplant Proc. 1996 Apr; 28(2):814-5.
    View in: PubMed
    Score: 0.009
  104. Zipris D, Greiner DL, Malkani S, Whalen B, Mordes JP, Rossini AA. Cytokine gene expression in islets and thyroids of BB rats. IFN-gamma and IL-12p40 mRNA increase with age in both diabetic and insulin-treated nondiabetic BB rats. J Immunol. 1996 Feb 01; 156(3):1315-21.
    View in: PubMed
    Score: 0.008
  105. Parker DC, Greiner DL, Phillips NE, Appel MC, Steele AW, Durie FH, Noelle RJ, Mordes JP, Rossini AA. Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand. Proc Natl Acad Sci U S A. 1995 Oct 10; 92(21):9560-4.
    View in: PubMed
    Score: 0.008
  106. Hesselton RM, Greiner DL, Mordes JP, Rajan TV, Sullivan JL, Shultz LD. High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice. J Infect Dis. 1995 Oct; 172(4):974-82.
    View in: PubMed
    Score: 0.008
  107. Whalen BJ, Greiner DL, Mordes JP, Rossini AA. Adoptive transfer of autoimmune diabetes mellitus to athymic rats: synergy of CD4+ and CD8+ T cells and prevention by RT6+ T cells. J Autoimmun. 1994 Dec; 7(6):819-31.
    View in: PubMed
    Score: 0.008
  108. Battan R, Mordes JP, Abreau S, Greiner DL, Handler ES, Rossini AA. Evidence that intrathymic islet transplantation does not prevent diabetes or subsequent islet graft destruction in RT6-depleted, diabetes-resistant BioBreeding/Worcester rats. Transplantation. 1994 Mar 15; 57(5):731-6.
    View in: PubMed
    Score: 0.007
  109. Tafuri A, Bowers WE, Handler ES, Appel M, Lew R, Greiner D, Mordes JP, Rossini AA. High stimulatory activity of dendritic cells from diabetes-prone BioBreeding/Worcester rats exposed to macrophage-derived factors. J Clin Invest. 1993 May; 91(5):2040-8.
    View in: PubMed
    Score: 0.007
  110. Kitagawa Y, Greiner DL, Reynolds CW, Ortaldo JR, Toccafondi R, Handler ES, van der Meide PH, Mordes JP, Rossini AA. Islet cells but not thyrocytes are susceptible to lysis by NK cells. J Autoimmun. 1991 Oct; 4(5):703-16.
    View in: PubMed
    Score: 0.006
  111. Gottlieb PA, Handler ES, Appel MC, Greiner DL, Mordes JP, Rossini AA. Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB/Wor rats. Diabetologia. 1991 May; 34(5):296-300.
    View in: PubMed
    Score: 0.006
  112. Woda BA, Handler ES, Greiner DL, Reynolds C, Mordes JP, Rossini AA. T-lymphocyte requirement for diabetes in RT6-depleted diabetes-resistant BB rats. Diabetes. 1991 Apr; 40(4):423-8.
    View in: PubMed
    Score: 0.006
  113. Thomas VA, Woda BA, Handler ES, Greiner DL, Mordes JP, Rossini AA. Altered expression of diabetes in BB/Wor rats by exposure to viral pathogens. Diabetes. 1991 Feb; 40(2):255-8.
    View in: PubMed
    Score: 0.006
  114. Cris? L, Greiner DL, Mordes JP, MacDonald RG, Handler ES, Czech MP, Rossini AA. Biochemical studies of RT6 alloantigens in BB/Wor and normal rats. Evidence for intact unexpressed RT6a structural gene in diabetes-prone BB rats. Diabetes. 1990 Oct; 39(10):1279-88.
    View in: PubMed
    Score: 0.006
  115. McKeever U, Mordes JP, Greiner DL, Appel MC, Rozing J, Handler ES, Rossini AA. Adoptive transfer of autoimmune diabetes and thyroiditis to athymic rats. Proc Natl Acad Sci U S A. 1990 Oct; 87(19):7618-22.
    View in: PubMed
    Score: 0.006
  116. Nakamura N, Woda BA, Tafuri A, Greiner DL, Reynolds CW, Ortaldo J, Chick W, Handler ES, Mordes JP, Rossini AA. Intrinsic cytotoxicity of natural killer cells to pancreatic islets in vitro. Diabetes. 1990 Jul; 39(7):836-43.
    View in: PubMed
    Score: 0.006
  117. Gottlieb PA, Berrios JP, Mariani G, Handler ES, Greiner D, Mordes JP, Rossini AA. Autoimmune destruction of islets transplanted into RT6-depleted diabetes-resistant BB/Wor rats. Diabetes. 1990 May; 39(5):643-5.
    View in: PubMed
    Score: 0.006
  118. Lefkowith J, Schreiner G, Cormier J, Handler ES, Driscoll HK, Greiner D, Mordes JP, Rossini AA. Prevention of diabetes in the BB rat by essential fatty acid deficiency. Relationship between physiological and biochemical changes. J Exp Med. 1990 Mar 01; 171(3):729-43.
    View in: PubMed
    Score: 0.006
  119. Handler ES, Mordes JP, McKeever U, Nakamura N, Bernhard J, Greiner DL, Rossini AA. Effects of irradiation on diabetes in the BB/Wor rat. Autoimmunity. 1989; 4(1-2):21-30.
    View in: PubMed
    Score: 0.005
  120. Burstein D, Mordes JP, Greiner DL, Stein D, Nakamura N, Handler ES, Rossini AA. Prevention of diabetes in BB/Wor rat by single transfusion of spleen cells. Parameters that affect degree of protection. Diabetes. 1989 Jan; 38(1):24-30.
    View in: PubMed
    Score: 0.005
  121. Angelillo M, Greiner DL, Mordes JP, Handler ES, Nakamura N, McKeever U, Rossini A. Absence of RT6+ T cells in diabetes-prone biobreeding/Worcester rats is due to genetic and cell developmental defects. J Immunol. 1988 Dec 15; 141(12):4146-51.
    View in: PubMed
    Score: 0.005
  122. Nakano K, Mordes JP, Handler ES, Greiner DL, Rossini AA. Role of host immune system in BB/Wor rat. Predisposition to diabetes resides in bone marrow. Diabetes. 1988 May; 37(5):520-5.
    View in: PubMed
    Score: 0.005
  123. Rossini AA, Mordes JP, Greiner DL, Nakano K, Appel MC, Handler ES. Spleen cell transfusion in the Bio-Breeding/Worcester rat. Prevention of diabetes, major histocompatibility complex restriction, and long-term persistence of transfused cells. J Clin Invest. 1986 Apr; 77(4):1399-401.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.