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Timothy P Fitzgibbons MD, PhD

TitleAssociate Professor
InstitutionUMass Chan Medical School
AddressUniversity of Massachusetts Medical School
55 Lake Ave North
Worcester MA 01605
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DivisionCardiovascular Medicine

    Collapse Biography 
    Collapse education and training
    Boston College, Chestnut Hill, MA, United StatesBSBiology
    Loyola University Stritch School of Medicine, Maywood, IL, United StatesMD
    University of Massachusetts Medical School, Worcester, MA, United StatesPHDMolecular Medicine

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cashman TJ, Fitzgibbons TP, Trivedi CM. Integrated Pathogenesis of Vascular and Cardiac Valve Disease. Circ Res. 2023 09; 133(6):481-483. PMID: 37651543.
      Citations:    Fields:    Translation:Humans
    2. Aurigemma GP, Gentile BA, Dickey JB, Fitzgibbons TP, Tighe DA, Kakouros N, Kovell LC, Gottbrecht MF, Narvaez-Guerra O, Qureshi W, Gerson DS, Parker MW. Insights Into the Standard Echocardiographic Views From Multimodality Imaging: Ventricles, Pericardium, Valves, and Atria. J Am Soc Echocardiogr. 2023 Aug 06. PMID: 37549797.
      Citations:    Fields:    
    3. Fitzgibbons TP. Epicardial Adipose-Derived miR92a-3p: Stress Reduction Therapy? J Am Coll Cardiol. 2023 07 25; 82(4):333-335. PMID: 37468188.
      Citations:    Fields:    Translation:Humans
    4. Vargas AI, Tarraf SA, Fitzgibbons TP, Bellini C, Amini R. Biomechanical remodeling of the murine descending thoracic aorta during late-gestation pregnancy. Curr Res Physiol. 2023; 6:100102. PMID: 37575979.
    5. Park G, Haley JA, Le J, Jung SM, Fitzgibbons TP, Korobkina ED, Li H, Fluharty SM, Chen Q, Spinelli JB, Trivedi CM, Jang C, Guertin DA. Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis. Nat Metab. 2023 07; 5(7):1204-1220. PMID: 37337122.
      Citations: 1     Fields:    Translation:Animals
    6. Gubala A, Venkatesh K, Akhter M, Meyer TE, Fitzgibbons TP. High-Output Heart Failure in a Patient With Klippel-Tr?naunay Syndrome: A Case Report. Cureus. 2023 May; 15(5):e38963. PMID: 37313059.
    7. Tran KV, Filippaios A, Noorishirazi K, Ding E, Han D, Mohagheghian F, Dai Q, Mehawej J, Wang Z, Lessard D, Otabil EM, Hamel A, Paul T, Gottbrecht MF, Fitzgibbons TP, Saczynski J, Chon KH, McManus DD. False Atrial Fibrillation Alerts from Smartwatches are Associated with Decreased Perceived Physical Well-being and Confidence in Chronic Symptoms Management. Cardiol Cardiovasc Med. 2023; 7(2):97-107. PMID: 37476150.
    8. Willar B, Tran KV, Fitzgibbons TP. Epicardial adipocytes in the pathogenesis of atrial fibrillation: An update on basic and translational studies. Front Endocrinol (Lausanne). 2023; 14:1154824. PMID: 37020587.
      Citations: 1     Fields:    Translation:HumansCells
    9. Fitzgibbons TP, Gottbrecht MF, Aurigemma GP. The Pathophysiology and Assessment of Diastolic Dysfunction: Important Clues From Stress Cardiomyopathy. J Am Soc Echocardiogr. 2023 05; 36(5):500-503. PMID: 36863946.
      Citations:    Fields:    Translation:Humans
    10. Mohagheghian F, Han D, Peitzsch A, Nishita N, Ding E, Dickson EL, DiMezza D, Otabil EM, Noorishirazi K, Scott J, Lessard D, Wang Z, Whitcomb C, Tran KV, Fitzgibbons TP, McManus DD, Chon KH. Optimized Signal Quality Assessment for Photoplethysmogram Signals Using Feature Selection. IEEE Trans Biomed Eng. 2022 09; 69(9):2982-2993. PMID: 35275809.
      Citations: 5     Fields:    Translation:Humans
    11. Han D, Bashar SK, L?zaro J, Mohagheghian F, Peitzsch A, Nishita N, Ding E, Dickson EL, DiMezza D, Scott J, Whitcomb C, Fitzgibbons TP, McManus DD, Chon KH. A Real-Time PPG Peak Detection Method for Accurate Determination of Heart Rate during Sinus Rhythm and Cardiac Arrhythmia. Biosensors (Basel). 2022 Jan 29; 12(2). PMID: 35200342.
      Citations: 7     Fields:    Translation:Humans
    12. Thomas P, Venugopalan A, Narayanan S, Mathew T, Cherukuwada LPD, Chandran S, Pradeep J, Fitzgibbons TP, George V. Case Report: Occurrence of Severe Thoracic Aortic Aneurysms (Involving the Ascending, Arch, and Descending Segments) as a Result of Fibulin-4 Deficiency: A Rare Pathology With Successful Management. Front Cardiovasc Med. 2021; 8:756765. PMID: 34901216.
    13. Dickson EL, Ding EY, Saczynski JS, Han D, Moonis M, Fitzgibbons TP, Barton B, Chon K, McManus DD. Smartwatch monitoring for atrial fibrillation after stroke-The Pulsewatch Study: Protocol for a multiphase randomized controlled trial. Cardiovasc Digit Health J. 2021 Aug; 2(4):231-241. PMID: 35265913.
    14. Elnazeir M, Nobel L, Narayanan S, Darmoch F, Massari F, Fitzgibbons T, Carandang RA, Jun-O'Connell A. Left Ventricular Noncompaction Cardiomyopathy as a Potential Cause of Bilateral Posterior Cerebral Artery Stroke - a Rare and Unique Clinical Occurrence. Am J Case Rep. 2021 Jun 22; 22:e931103. PMID: 34157014.
      Citations: 2     Fields:    Translation:Humans
    15. Bashar SK, Hossain MB, L?zaro J, Ding EY, Noh Y, Cho CH, McManus DD, Fitzgibbons TP, Chon KH. Feasibility of atrial fibrillation detection from a novel wearable armband device. Cardiovasc Digit Health J. 2021 Jun; 2(3):179-191. PMID: 35265907.
    16. Choudhary KV, Kakouros N, Aurigemma GP, Parker MW, Fitzgibbons T. Differentiating Pseudo Versus True Aortic Stenosis in Patients Without Contractile Reserve: A Diagnostic Dilemma. Cureus. 2021 Mar 24; 13(3):e14086. PMID: 33903843.
    17. Bashar SK, Han D, Zieneddin F, Ding E, Fitzgibbons TP, Walkey AJ, McManus DD, Javidi B, Chon KH. Novel Density Poincar? Plot Based Machine Learning Method to Detect Atrial Fibrillation From Premature Atrial/Ventricular Contractions. IEEE Trans Biomed Eng. 2021 02; 68(2):448-460. PMID: 32746035.
      Citations: 9     Fields:    Translation:Humans
    18. Luo J, Weaver MS, Fitzgibbons TP, Aouadi M, Czech MP, Allen MD. Immunotherapy for Infarcts: In Vivo Postinfarction Macrophage Modulation Using Intramyocardial Microparticle Delivery of Map4k4 Small Interfering RNA. Biores Open Access. 2020; 9(1):258-268. PMID: 33376632.
    19. Fitzgibbons TP, Aurigemma GP. How Do Adrenergic Tumors Affect Left Ventricular Remodeling and Function?: A "Loaded" Question. JACC Cardiovasc Imaging. 2020 12; 13(12):2510-2512. PMID: 33221239.
      Citations: 2     Fields:    Translation:Humans
    20. Ding EY, Svennberg E, Wurster C, Duncker D, Manninger M, Lubitz SA, Dickson E, Fitzgibbons TP, Akoum N, Al-Khatib SM, Attia ZI, Ghanbari H, Marrouche NF, Mendenhall GS, Peters NS, Tarakji KG, Turakhia M, Wan EY, McManus DD. Survey of current perspectives on consumer-available digital health devices for detecting atrial fibrillation. Cardiovasc Digit Health J. 2020 Jul-Aug; 1(1):21-29. PMID: 32924024.
    21. Fitzgibbons TP. Effect of Weight Gain on Skeletal Muscle and Adipose Tissue Perfusion: Human Fat Goes With the Flow. Arterioscler Thromb Vasc Biol. 2020 07; 40(7):1617-1619. PMID: 32579478.
      Citations: 1     Fields:    Translation:HumansCells
    22. Tran KV, Brown EL, DeSouza T, Jespersen NZ, Nandrup-Bus C, Yang Q, Yang Z, Desai A, Min SY, Rojas-Rodriguez R, Lundh M, Feizi A, Willenbrock H, Larsen TJ, Severinsen MCK, Malka K, Mozzicato AM, Deshmukh AS, Emanuelli B, Pedersen BK, Fitzgibbons T, Scheele C, Corvera S, Nielsen S. Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473. Nat Metab. 2020 05; 2(5):397-412. PMID: 32440655.
      Citations: 28     Fields:    Translation:HumansCells
    23. Ahmed M, Sardana M, Rasla S, Escobar J, Bote J, Iskandar A, Tran KV, Tighe DA, Fitzgibbons TP, Aurigemma GP. Comparative left ventricular mechanical deformation in acute apical variant stress cardiomyopathy and acute anterior myocardial infarction utilizing 2-dimensional longitudinal strain imaging. Echocardiography. 2020 06; 37(6):832-840. PMID: 32437588.
      Citations: 2     Fields:    Translation:Humans
    24. Fitzgibbons TP, Lee N, Tran KV, Nicoloro S, Kelly M, Tam SK, Czech MP. Coronary disease is not associated with robust alterations in inflammatory gene expression in human epicardial fat. JCI Insight. 2019 10 17; 4(20). PMID: 31513547.
      Citations: 11     Fields:    Translation:Humans
    25. Ding EY, Ensom E, Hafer N, Buchholz B, Picard MA, Dunlap D, Rogers E, Lawton C, Koren A, Lilly C, Fitzgibbons TP, McManus DD. Point-of-care technologies in heart, lung, blood and sleep disorders from the Center for Advancing Point-of-Care Technologies. Curr Opin Biomed Eng. 2019 Sep; 11:58-67. PMID: 32582870.
    26. Tran KV, Majka J, Sanghai S, Sardana M, Lessard D, Milstone Z, Tanriverdi K, Freedman JE, Fitzgibbons TP, McManus D. Micro-RNAs Are Related to Epicardial Adipose Tissue in Participants With Atrial Fibrillation: Data From the MiRhythm Study. Front Cardiovasc Med. 2019; 6:115. PMID: 31475159.
    27. Ding EY, Han D, Whitcomb C, Bashar SK, Adaramola O, Soni A, Saczynski J, Fitzgibbons TP, Moonis M, Lubitz SA, Lessard D, Hills MT, Barton B, Chon K, McManus DD. Accuracy and Usability of a Novel Algorithm for Detection of Irregular Pulse Using a Smartwatch Among Older Adults: Observational Study. JMIR Cardio. 2019 May 15; 3(1):e13850. PMID: 31758787.
    28. Iskandar A, Mowakeaa S, Sardana M, Fitzgibbons TP, Tighe DA, Parker MW, Kakouros N, McManus D, Aurigemma GP. The presbycardia phenotype: Cardiac remodeling and valvular degeneration in nonagenarians. Echocardiography. 2018 12; 35(12):1974-1981. PMID: 30431175.
      Citations: 3     Fields:    Translation:Humans
    29. Li Y, Fitzgibbons TP, McManus DD, Goddeau RP, Silver B, Henninger N. Left Ventricular Ejection Fraction and Clinically Defined Heart Failure to Predict 90-Day Functional Outcome After Ischemic Stroke. J Stroke Cerebrovasc Dis. 2019 Feb; 28(2):371-380. PMID: 30396839.
      Citations: 10     Fields:    Translation:Humans
    30. Sanghai SR, Sardana M, Hansra B, Lessard DM, Dahlberg ST, Aurigemma GP, Fitzgibbons TP, McManus DD. Indexed Left Atrial Adipose Tissue Area Is Associated With Severity of Atrial Fibrillation and Atrial Fibrillation Recurrence Among Patients Undergoing Catheter Ablation. Front Cardiovasc Med. 2018; 5:76. PMID: 29971239.
    31. Tran KV, Fitzgibbons T, Min SY, DeSouza T, Corvera S. Distinct adipocyte progenitor cells are associated with regional phenotypes of perivascular aortic fat in mice. Mol Metab. 2018 03; 9:199-206. PMID: 29396370.
      Citations: 18     Fields:    Translation:AnimalsCells
    32. King KR, Aguirre AD, Ye YX, Sun Y, Roh JD, Ng RP, Kohler RH, Arlauckas SP, Iwamoto Y, Savol A, Sadreyev RI, Kelly M, Fitzgibbons TP, Fitzgerald KA, Mitchison T, Libby P, Nahrendorf M, Weissleder R. IRF3 and type I interferons fuel a fatal response to myocardial infarction. Nat Med. 2017 Dec; 23(12):1481-1487. PMID: 29106401.
      Citations: 185     Fields:    Translation:AnimalsCells
    33. Fitzgibbons TP, Edwards YJK, Shaw P, Iskandar A, Ahmed M, Bote J, Shah T, Sinha S, Gerszten RE, Keaney JF, Zile MR, Aurigemma GP. Activation of Inflammatory and Pro-Thrombotic Pathways in Acute Stress Cardiomyopathy. Front Cardiovasc Med. 2017; 4:49. PMID: 28824923.
    34. Saddic LA, Nicoloro SM, Gupta OT, Czech MP, Gorham J, Shernan SK, Seidman CE, Seidman JG, Aranki SF, Body SC, Fitzgibbons TP, Muehlschlegel JD. Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia. Cardiovasc Diabetol. 2017 07 07; 16(1):87. PMID: 28687077.
      Citations: 8     Fields:    Translation:Humans
    35. Grover P, Fitzgibbons TP. Spontaneous coronary artery dissection in a patient with autosomal dominant polycystic kidney disease: a case report. J Med Case Rep. 2016 Mar 10; 10:62. PMID: 26971055.
      Citations: 6     Fields:    Translation:Humans
    36. Fitzgibbons TP, Czech MP. Emerging evidence for beneficial macrophage functions in atherosclerosis and obesity-induced insulin resistance. J Mol Med (Berl). 2016 Mar; 94(3):267-75. PMID: 26847458.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    37. Min SY, Kady J, Nam M, Rojas-Rodriguez R, Berkenwald A, Kim JH, Noh HL, Kim JK, Cooper MP, Fitzgibbons T, Brehm MA, Corvera S. Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice. Nat Med. 2016 Mar; 22(3):312-8. PMID: 26808348.
      Citations: 134     Fields:    Translation:HumansAnimalsCells
    38. Roth Flach RJ, Skoura A, Matevossian A, Danai LV, Zheng W, Cortes C, Bhattacharya SK, Aouadi M, Hagan N, Yawe JC, Vangala P, Menendez LG, Cooper MP, Fitzgibbons TP, Buckbinder L, Czech MP. Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis. Nat Commun. 2015 Dec 21; 6:8995. PMID: 26688060.
      Citations: 44     Fields:    Translation:AnimalsCells
    39. Kundu A, Fitzgibbons TP. Acute symptomatic sinus bradycardia in a woman treated with pulse dose steroids for multiple sclerosis: a case report. J Med Case Rep. 2015 Sep 24; 9:216. PMID: 26400725.
      Citations: 4     Fields:    Translation:Humans
    40. Craige SM, Kant S, Reif M, Chen K, Pei Y, Angoff R, Sugamura K, Fitzgibbons T, Keaney JF. Endothelial NADPH oxidase 4 protects ApoE-/- mice from atherosclerotic lesions. Free Radic Biol Med. 2015 Dec; 89:1-7. PMID: 26169727.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    41. Fitzgibbons TP, Aurigemma GP. Making "Waves" With a Murine Model of Aortic Insufficiency. Arterioscler Thromb Vasc Biol. 2015 Jul; 35(7):1554-6. PMID: 26109738.
      Citations:    Fields:    Translation:Animals
    42. Fitzgibbons T, Aurigemma G. Serial changes in diastolic function: lessons from the growing field of echo-epidemiology. Circ Cardiovasc Imaging. 2015 Apr; 8(4). PMID: 25873724.
      Citations:    Fields:    Translation:Humans
    43. Medeiros K, O'Connor M, Baicu CF, Fitzgibbons T, Shaw P, Tighe DA, Zile MR, Aurigemma GP. Response to letters regarding article, "systolic and diastolic mechanics in stress cardiomyopathy". Circulation. 2015 Mar 10; 131(10):e372. PMID: 25753351.
      Citations:    Fields:    Translation:Humans
    44. Fitzgibbons TP. Stress cardiomyopathy: Thinking outside the octopus pot. Trends Cardiovasc Med. 2015 May; 25(4):358-9. PMID: 25576034.
      Citations:    Fields:    Translation:Humans
    45. Fitzgibbons TP, Czech MP. Epicardial and perivascular adipose tissues and their influence on cardiovascular disease: basic mechanisms and clinical associations. J Am Heart Assoc. 2014 Mar 04; 3(2):e000582. PMID: 24595191.
      Citations: 132     Fields:    Translation:HumansAnimalsCells
    46. Medeiros K, O'Connor MJ, Baicu CF, Fitzgibbons TP, Shaw P, Tighe DA, Zile MR, Aurigemma GP. Systolic and diastolic mechanics in stress cardiomyopathy. Circulation. 2014 Apr 22; 129(16):1659-67. PMID: 24503950.
      Citations: 33     Fields:    Translation:Humans
    47. Fitzgibbons TP, Paolino J, Dagorn JC, Meyer TE. Usefulness of pancreatitis-associated protein, a novel biomarker, to predict severity of disease in ambulatory patients with heart failure. Am J Cardiol. 2014 Jan 01; 113(1):123-6. PMID: 24188888.
      Citations: 4     Fields:    Translation:Humans
    48. Aurigemma GP, de Simone G, Fitzgibbons T. Response to letter regarding article, "Cardiac remodeling in obesity". Circ Cardiovasc Imaging. 2013 May 01; 6(3):e18. PMID: 23696589.
      Citations:    Fields:    Translation:Humans
    49. Aurigemma GP, de Simone G, Fitzgibbons TP. Cardiac remodeling in obesity. Circ Cardiovasc Imaging. 2013 Jan 01; 6(1):142-52. PMID: 23322729.
      Citations: 76     Fields:    Translation:Humans
    50. Fitzgibbons TP, Kogan S, Aouadi M, Hendricks GM, Straubhaar J, Czech MP. Similarity of mouse perivascular and brown adipose tissues and their resistance to diet-induced inflammation. Am J Physiol Heart Circ Physiol. 2011 Oct; 301(4):H1425-37. PMID: 21765057.
      Citations: 153     Fields:    Translation:AnimalsCells
    51. Madias C, Fitzgibbons TP, Alsheikh-Ali AA, Bouchard JL, Kalsmith B, Garlitski AC, Tighe DA, Estes NA, Aurigemma GP, Link MS. Acquired long QT syndrome from stress cardiomyopathy is associated with ventricular arrhythmias and torsades de pointes. Heart Rhythm. 2011 Apr; 8(4):555-61. PMID: 21146632.
      Citations: 48     Fields:    Translation:Humans
    52. Fitzgibbons TP, Hardy OT, Lessard D, Gore JM, Yarzebski J, Goldberg RJ. Body mass index, treatment practices, and mortality in patients with acute heart failure. Coron Artery Dis. 2009 Dec; 20(8):536-43. PMID: 19884822.
      Citations: 4     Fields:    Translation:Humans
    53. Fitzgibbons TP, Madias C, Seth A, Bouchard JL, Kuvin JT, Patel AR, Pandian NG, Meyer TE, Aurigemma GP, Tighe DA. Prevalence and clinical characteristics of right ventricular dysfunction in transient stress cardiomyopathy. Am J Cardiol. 2009 Jul 01; 104(1):133-6. PMID: 19576334.
      Citations: 8     Fields:    Translation:Humans
    54. Fitzgibbons TP, Meyer TE, Aurigemma GP. Mortality in diastolic heart failure: an update. Cardiol Rev. 2009 Mar-Apr; 17(2):51-5. PMID: 19367145.
      Citations: 4     Fields:    Translation:Humans
    55. Fitzgibbons TP. Isosorbide dinitrate and hydralazine in blacks with heart failure. N Engl J Med. 2005 Mar 10; 352(10):1041-3; author reply 1041-3. PMID: 15761998.
      Citations:    Fields:    Translation:Humans
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