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Patricia J Giardina CNM

InstitutionUMass Chan Medical School
DepartmentObstetrics and Gynecology
AddressAndrea M. Boedine MD Office of Gynecology
740 Williams Street, Suite 9
Pittsfield MA 01201
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentObstetrics and Gynecology
    DivisionGeneral Ob/Gyn

    Collapse Biography 
    Collapse education and training
    Massachusetts College of Liberal Arts, North Adams, MA, United StatesBAInterdisciplinary Studies

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chapin J, Cohen AR, Neufeld EJ, Vichinsky E, Giardina PJ, Boudreaux J, Le BC, Kenney K, Trimble S, Thompson AA. An update on the US adult thalassaemia population: a report from the CDC thalassaemia treatment centres. Br J Haematol. 2022 01; 196(2):380-389. PMID: 34775608.
      Citations:    Fields:    Translation:HumansPHPublic Health
    2. Vichinsky E, Cohen A, Thompson AA, Giardina PJ, Lal A, Paley C, Cheng WY, McCormick N, Sasane M, Qiu Y, Kwiatkowski JL. Epidemiologic and clinical characteristics of nontransfusion-dependent thalassemia in the United States. Pediatr Blood Cancer. 2018 07; 65(7):e27067. PMID: 29637688.
      Citations: 5     Fields:    Translation:Humans
    3. Taher AT, Saliba AN, Kuo KH, Giardina PJ, Cohen AR, Neufeld EJ, Aydinok Y, Kwiatkowski JL, Jeglinski BI, Pietropaolo K, Berk G, Viprakasit V. Safety and pharmacokinetics of the oral iron chelator SP-420 in ?-thalassemia. Am J Hematol. 2017 Dec; 92(12):1356-1361. PMID: 28940308.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    4. Spitzer B, Giardina PJ, O'Reilly RJ, Boulad F. Late complications of mixed chimerism following allogeneic bone marrow transplantation for thalassemia major. Pediatr Blood Cancer. 2015 Jul; 62(7):1303-4. PMID: 25810133.
      Citations: 1     Fields:    Translation:Humans
    5. Chakraborty PK, Schmitz-Abe K, Kennedy EK, Mamady H, Naas T, Durie D, Campagna DR, Lau A, Sendamarai AK, Wiseman DH, May A, Jolles S, Connor P, Powell C, Heeney MM, Giardina PJ, Klaassen RJ, Kannengiesser C, Thuret I, Thompson AA, Marques L, Hughes S, Bonney DK, Bottomley SS, Wynn RF, Laxer RM, Minniti CP, Moppett J, Bordon V, Geraghty M, Joyce PB, Markianos K, Rudner AD, Holcik M, Fleming MD. Mutations in TRNT1 cause congenital sideroblastic anemia with immunodeficiency, fevers, and developmental delay (SIFD). Blood. 2014 Oct 30; 124(18):2867-71. PMID: 25193871.
      Citations: 70     Fields:    Translation:HumansCells
    6. Harvey MM, Coifman KG, Ross G, Kleinert D, Giardina P. Contextually appropriate emotional word use predicts adaptive health behavior: Emotion context sensitivity and treatment adherence. J Health Psychol. 2016 05; 21(5):579-89. PMID: 24801328.
      Citations: 9     Fields:    Translation:Humans
    7. Goss C, Giardina P, Degtyaryova D, Kleinert D, Sheth S, Cushing M. Red blood cell transfusions for thalassemia: results of a survey assessing current practice and proposal of evidence-based guidelines. Transfusion. 2014 Jul; 54(7):1773-81. PMID: 24611697.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    8. Coifman KG, Ross GS, Kleinert D, Giardina P. Negative affect differentiation and adherence during treatment for thalassemia. Int J Behav Med. 2014 Feb; 21(1):160-8. PMID: 23086716.
      Citations: 3     Fields:    Translation:Humans
    9. Boulad F, Wang X, Qu J, Taylor C, Ferro L, Karponi G, Bartido S, Giardina P, Heller G, Prockop SE, Maggio A, Sadelain M, Rivi?re I. Safe mobilization of CD34+ cells in adults with ?-thalassemia and validation of effective globin gene transfer for clinical investigation. Blood. 2014 Mar 06; 123(10):1483-6. PMID: 24429337.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    10. Vichinsky E, Neumayr L, Trimble S, Giardina PJ, Cohen AR, Coates T, Boudreaux J, Neufeld EJ, Kenney K, Grant A, Thompson AA. Transfusion complications in thalassemia patients: a report from the Centers for Disease Control and Prevention (CME). Transfusion. 2014 Apr; 54(4):972-81; quiz 971. PMID: 23889533.
      Citations: 34     Fields:    Translation:HumansPHPublic Health
    11. Thompson AA, Kim HY, Singer ST, Vichinsky E, Eile J, Yamashita R, Giardina PJ, Olivieri N, Parmar N, Trachtenberg F, Neufeld EJ, Kwiatkowski JL. Pregnancy outcomes in women with thalassemia in North America and the United Kingdom. Am J Hematol. 2013 Sep; 88(9):771-3. PMID: 23757266.
      Citations: 4     Fields:    Translation:Humans
    12. Ambati SR, Randolph RE, Mennitt K, Kleinert DA, Weinsaft JW, Giardina PJ. Longitudinal monitoring of cardiac siderosis using cardiovascular magnetic resonance T2* in patients with thalassemia major on various chelation regimens: a 6-year study. Am J Hematol. 2013 Aug; 88(8):652-6. PMID: 23640778.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    13. Porter JB, Wood J, Olivieri N, Vichinsky EP, Taher A, Neufeld E, Giardina P, Thompson A, Moore B, Evans P, Kim HY, Macklin EA, Trachtenberg F. Treatment of heart failure in adults with thalassemia major: response in patients randomised to deferoxamine with or without deferiprone. J Cardiovasc Magn Reson. 2013 May 20; 15:38. PMID: 23688265.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    14. Goldberg SL, Giardina PJ, Chirnomas D, Esposito J, Paley C, Vichinsky E. The palatability and tolerability of deferasirox taken with different beverages or foods. Pediatr Blood Cancer. 2013 Sep; 60(9):1507-12. PMID: 23637051.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    15. Choudhary A, Giardina P, Antal Z, Vogiatzi M. Unreliable oral glucose tolerance test and haemoglobin A1C in beta thalassaemia major--a case for continuous glucose monitoring? Br J Haematol. 2013 Jul; 162(1):132-5. PMID: 23594287.
      Citations: 6     Fields:    Translation:Humans
    16. Wiseman DH, May A, Jolles S, Connor P, Powell C, Heeney MM, Giardina PJ, Klaassen RJ, Chakraborty P, Geraghty MT, Major-Cook N, Kannengiesser C, Thuret I, Thompson AA, Marques L, Hughes S, Bonney DK, Bottomley SS, Fleming MD, Wynn RF. A novel syndrome of congenital sideroblastic anemia, B-cell immunodeficiency, periodic fevers, and developmental delay (SIFD). Blood. 2013 Jul 04; 122(1):112-23. PMID: 23553769.
      Citations: 39     Fields:    Translation:HumansCells
    17. Ramos P, Casu C, Gardenghi S, Breda L, Crielaard BJ, Guy E, Marongiu MF, Gupta R, Levine RL, Abdel-Wahab O, Ebert BL, Van Rooijen N, Ghaffari S, Grady RW, Giardina PJ, Rivella S. Macrophages support pathological erythropoiesis in polycythemia vera and ?-thalassemia. Nat Med. 2013 Apr; 19(4):437-45. PMID: 23502961.
      Citations: 116     Fields:    Translation:HumansAnimalsCells
    18. Switzer WM, Shankar A, Trimble SR, Thompson AA, Giardina PJ, Cohen AR, Coates TD, Vichinsky E, Neufeld EJ, Boudreaux JM, Heneine W. Human T cell lymphotropic virus type 1 infection among U.S. thalassemia patients. AIDS Res Hum Retroviruses. 2013 Jul; 29(7):1006-9. PMID: 23409829.
      Citations: 2     Fields:    Translation:Humans
    19. Green NS, Ender KL, Pashankar F, Driscoll C, Giardina PJ, Mullen CA, Clark LN, Manwani D, Crotty J, Kisselev S, Neville KA, Hoppe C, Barral S. Candidate sequence variants and fetal hemoglobin in children with sickle cell disease treated with hydroxyurea. PLoS One. 2013; 8(2):e55709. PMID: 23409025.
      Citations: 12     Fields:    Translation:Humans
    20. Walter PB, Porter J, Evans P, Kwiatkowski JL, Neufeld EJ, Coates T, Giardina PJ, Grady RW, Vichinsky E, Olivieri N, Trachtenberg F, Alberti D, Fung E, Ames B, Higa A, Harmatz P. Increased leucocyte apoptosis in transfused ?-thalassaemia patients. Br J Haematol. 2013 Feb; 160(3):399-403. PMID: 23216540.
      Citations: 3     Fields:    Translation:HumansCells
    21. Oyeku SO, Driscoll MC, Cohen HW, Trachtman R, Pashankar F, Mullen C, Giardina PJ, Velazco N, Racine AD, Green NS. Parental and other factors associated with hydroxyurea use for pediatric sickle cell disease. Pediatr Blood Cancer. 2013 Apr; 60(4):653-8. PMID: 23129068.
      Citations: 31     Fields:    Translation:Humans
    22. Grady RW, Galanello R, Randolph RE, Kleinert DA, Dessi C, Giardina PJ. Toward optimizing the use of deferasirox: potential benefits of combined use with deferoxamine. Haematologica. 2013 Jan; 98(1):129-35. PMID: 22875626.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    23. Breda L, Casu C, Gardenghi S, Bianchi N, Cartegni L, Narla M, Yazdanbakhsh K, Musso M, Manwani D, Little J, Gardner LB, Kleinert DA, Prus E, Fibach E, Grady RW, Giardina PJ, Gambari R, Rivella S. Therapeutic hemoglobin levels after gene transfer in ?-thalassemia mice and in hematopoietic cells of ?-thalassemia and sickle cells disease patients. PLoS One. 2012; 7(3):e32345. PMID: 22479321.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    24. Kwiatkowski JL, Kim HY, Thompson AA, Quinn CT, Mueller BU, Odame I, Giardina PJ, Vichinsky EP, Boudreaux JM, Cohen AR, Porter JB, Coates T, Olivieri NF, Neufeld EJ. Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort. Blood. 2012 Mar 22; 119(12):2746-53. PMID: 22279056.
      Citations: 26     Fields:    Translation:Humans
    25. Rachmilewitz EA, Giardina PJ. How I treat thalassemia. Blood. 2011 Sep 29; 118(13):3479-88. PMID: 21813448.
      Citations: 102     Fields:    Translation:Humans
    26. Morris CR, Kim HY, Trachtenberg F, Wood J, Quinn CT, Sweeters N, Kwiatkowski JL, Thompson AA, Giardina PJ, Boudreaux J, Olivieri NF, Porter JB, Neufeld EJ, Vichinsky EP. Risk factors and mortality associated with an elevated tricuspid regurgitant jet velocity measured by Doppler-echocardiography in thalassemia: a Thalassemia Clinical Research Network report. Blood. 2011 Oct 06; 118(14):3794-802. PMID: 21772051.
      Citations: 15     Fields:    Translation:Humans
    27. Trachtenberg F, Vichinsky E, Haines D, Pakbaz Z, Mednick L, Sobota A, Kwiatkowski J, Thompson AA, Porter J, Coates T, Giardina PJ, Olivieri N, Yamashita R, Neufeld EJ. Iron chelation adherence to deferoxamine and deferasirox in thalassemia. Am J Hematol. 2011 May; 86(5):433-6. PMID: 21523808.
      Citations: 23     Fields:    Translation:Humans
    28. Wood JC, Glynos T, Thompson A, Giardina P, Harmatz P, Kang BP, Paley C, Coates TD. Relationship between labile plasma iron, liver iron concentration and cardiac response in a deferasirox monotherapy trial. Haematologica. 2011 Jul; 96(7):1055-8. PMID: 21393329.
      Citations: 16     Fields:    Translation:HumansCTClinical Trials
    29. Quinn CT, Johnson VL, Kim HY, Trachtenberg F, Vogiatzi MG, Kwiatkowski JL, Neufeld EJ, Fung E, Oliveri N, Kirby M, Giardina PJ. Renal dysfunction in patients with thalassaemia. Br J Haematol. 2011 Apr; 153(1):111-7. PMID: 21332704.
      Citations: 25     Fields:    Translation:Humans
    30. Thompson AA, Cunningham MJ, Singer ST, Neufeld EJ, Vichinsky E, Yamashita R, Giardina P, Kim HY, Trachtenberg F, Kwiatkowski JL. Red cell alloimmunization in a diverse population of transfused patients with thalassaemia. Br J Haematol. 2011 Apr; 153(1):121-8. PMID: 21323889.
      Citations: 33     Fields:    Translation:HumansCells
    31. Papapetrou EP, Lee G, Malani N, Setty M, Riviere I, Tirunagari LM, Kadota K, Roth SL, Giardina P, Viale A, Leslie C, Bushman FD, Studer L, Sadelain M. Genomic safe harbors permit high ?-globin transgene expression in thalassemia induced pluripotent stem cells. Nat Biotechnol. 2011 Jan; 29(1):73-8. PMID: 21151124.
      Citations: 157     Fields:    Translation:HumansAnimalsCells
    32. Gardenghi S, Ramos P, Marongiu MF, Melchiori L, Breda L, Guy E, Muirhead K, Rao N, Roy CN, Andrews NC, Nemeth E, Follenzi A, An X, Mohandas N, Ginzburg Y, Rachmilewitz EA, Giardina PJ, Grady RW, Rivella S. Hepcidin as a therapeutic tool to limit iron overload and improve anemia in ?-thalassemic mice. J Clin Invest. 2010 Dec; 120(12):4466-77. PMID: 21099112.
      Citations: 119     Fields:    Translation:HumansAnimalsCells
    33. Wood JC, Glynos T, Thompson A, Giardina P, Harmatz P, Kang BP, Paley C, Coates TD. Follow-up report on the 2-year cardiac data from a deferasirox monotherapy trial. Am J Hematol. 2010 Oct; 85(10):818-9. PMID: 20799360.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    34. Mednick L, Yu S, Trachtenberg F, Xu Y, Kleinert DA, Giardina PJ, Kwiatkowski JL, Foote D, Thayalasuthan V, Porter JB, Thompson AA, Schilling L, Quinn CT, Neufeld EJ, Yamashita R. Symptoms of depression and anxiety in patients with thalassemia: prevalence and correlates in the thalassemia longitudinal cohort. Am J Hematol. 2010 Oct; 85(10):802-5. PMID: 20806230.
      Citations: 18     Fields:    Translation:Humans
    35. Pakbaz Z, Treadwell M, Kim HY, Trachtenberg F, Parmar N, Kwiatkowski JL, Cunningham MJ, Martin M, Sweeters N, Neufeld EJ, Giardina PJ, Olivieri N, Yamashita RC, Vichinsky E. Education and employment status of children and adults with thalassemia in North America. Pediatr Blood Cancer. 2010 Oct; 55(4):678-83. PMID: 20535817.
      Citations: 1     Fields:    Translation:Humans
    36. Sadelain M, Rivi?re I, Wang X, Boulad F, Prockop S, Giardina P, Maggio A, Galanello R, Locatelli F, Yannaki E. Strategy for a multicenter phase I clinical trial to evaluate globin gene transfer in beta-thalassemia. Ann N Y Acad Sci. 2010 Aug; 1202:52-8. PMID: 20712772.
      Citations: 17     Fields:    Translation:HumansAnimals
    37. Galanello R, Agus A, Campus S, Danjou F, Giardina PJ, Grady RW. Combined iron chelation therapy. Ann N Y Acad Sci. 2010 Aug; 1202:79-86. PMID: 20712777.
      Citations: 12     Fields:    Translation:Humans
    38. Breda L, Kleinert DA, Casu C, Casula L, Cartegni L, Fibach E, Mancini I, Giardina PJ, Gambari R, Rivella S. A preclinical approach for gene therapy of beta-thalassemia. Ann N Y Acad Sci. 2010 Aug; 1202:134-40. PMID: 20712784.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    39. Gardenghi S, Ramos P, Follenzi A, Rao N, Rachmilewitz EA, Giardina PJ, Grady RW, Rivella S. Hepcidin and Hfe in iron overload in beta-thalassemia. Ann N Y Acad Sci. 2010 Aug; 1202:221-5. PMID: 20712796.
      Citations: 9     Fields:    Translation:HumansAnimals
    40. Tsay J, Yang Z, Ross FP, Cunningham-Rundles S, Lin H, Coleman R, Mayer-Kuckuk P, Doty SB, Grady RW, Giardina PJ, Boskey AL, Vogiatzi MG. Bone loss caused by iron overload in a murine model: importance of oxidative stress. Blood. 2010 Oct 07; 116(14):2582-9. PMID: 20554970.
      Citations: 111     Fields:    Translation:Animals
    41. Fung EB, Xu Y, Kwiatkowski JL, Vogiatzi MG, Neufeld E, Olivieri N, Vichinsky EP, Giardina PJ. Relationship between chronic transfusion therapy and body composition in subjects with thalassemia. J Pediatr. 2010 Oct; 157(4):641-7, 647.e1-2. PMID: 20547400.
      Citations: 9     Fields:    Translation:Humans
    42. Vogiatzi MG, Tsay J, Verdelis K, Rivella S, Grady RW, Doty S, Giardina PJ, Boskey AL. Changes in bone microarchitecture and biomechanical properties in the th3 thalassemia mouse are associated with decreased bone turnover and occur during the period of bone accrual. Calcif Tissue Int. 2010 Jun; 86(6):484-94. PMID: 20449578.
      Citations: 18     Fields:    Translation:Animals
    43. Trachtenberg F, Foote D, Martin M, Carson S, Coates T, Beams O, Vega O, Merelles-Pulcini M, Giardina PJ, Kleinert DA, Kwiatkowski J, Thompson AA, Neufeld EJ, Schilling L, Thayalasuthan V, Pakbaz Z, Yamashita R. Pain as an emergent issue in thalassemia. Am J Hematol. 2010 May; 85(5):367-70. PMID: 20232403.
      Citations: 11     Fields:    Translation:Humans
    44. Wood JC, Kang BP, Thompson A, Giardina P, Harmatz P, Glynos T, Paley C, Coates TD. The effect of deferasirox on cardiac iron in thalassemia major: impact of total body iron stores. Blood. 2010 Jul 29; 116(4):537-43. PMID: 20421452.
      Citations: 45     Fields:    Translation:HumansCTClinical Trials
    45. Singer ST, Kim HY, Olivieri NF, Kwiatkowski JL, Coates TD, Carson S, Neufeld E, Cunningham MJ, Giardina PJ, Mueller BU, Quinn CT, Fung E, Vichinsky E. Hemoglobin H-constant spring in North America: an alpha thalassemia with frequent complications. Am J Hematol. 2009 Nov; 84(11):759-61. PMID: 19787795.
      Citations: 4     Fields:    Translation:Humans
    46. Vogiatzi MG, Macklin EA, Trachtenberg FL, Fung EB, Cheung AM, Vichinsky E, Olivieri N, Kirby M, Kwiatkowski JL, Cunningham M, Holm IA, Fleisher M, Grady RW, Peterson CM, Giardina PJ. Differences in the prevalence of growth, endocrine and vitamin D abnormalities among the various thalassaemia syndromes in North America. Br J Haematol. 2009 Sep; 146(5):546-56. PMID: 19604241.
      Citations: 50     Fields:    Translation:Humans
    47. Vogiatzi MG, Macklin EA, Fung EB, Cheung AM, Vichinsky E, Olivieri N, Kirby M, Kwiatkowski JL, Cunningham M, Holm IA, Lane J, Schneider R, Fleisher M, Grady RW, Peterson CC, Giardina PJ. Bone disease in thalassemia: a frequent and still unresolved problem. J Bone Miner Res. 2009 Mar; 24(3):543-57. PMID: 18505376.
      Citations: 80     Fields:    Translation:Humans
    48. Harmatz P, Jonas MM, Kwiatkowski JL, Wright EC, Fischer R, Vichinsky E, Giardina PJ, Neufeld EJ, Porter J, Olivieri N. Safety and efficacy of pegylated interferon alpha-2a and ribavirin for the treatment of hepatitis C in patients with thalassemia. Haematologica. 2008 Aug; 93(8):1247-51. PMID: 18556414.
      Citations: 12     Fields:    Translation:HumansCellsCTClinical Trials
    49. Libani IV, Guy EC, Melchiori L, Schiro R, Ramos P, Breda L, Scholzen T, Chadburn A, Liu Y, Kernbach M, Baron-L?hr B, Porotto M, de Sousa M, Rachmilewitz EA, Hood JD, Cappellini MD, Giardina PJ, Grady RW, Gerdes J, Rivella S. Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in beta-thalassemia. Blood. 2008 Aug 01; 112(3):875-85. PMID: 18480424.
      Citations: 84     Fields:    Translation:AnimalsCells
    50. Walter PB, Macklin EA, Porter J, Evans P, Kwiatkowski JL, Neufeld EJ, Coates T, Giardina PJ, Vichinsky E, Olivieri N, Alberti D, Holland J, Harmatz P. Inflammation and oxidant-stress in beta-thalassemia patients treated with iron chelators deferasirox (ICL670) or deferoxamine: an ancillary study of the Novartis CICL670A0107 trial. Haematologica. 2008 Jun; 93(6):817-25. PMID: 18469351.
      Citations: 25     Fields:    Translation:HumansCellsCTClinical Trials
    51. Fung EB, Harmatz PR, Milet M, Coates TD, Thompson AA, Ranalli M, Mignaca R, Scher C, Giardina P, Robertson S, Neumayr L, Vichinsky EP. Fracture prevalence and relationship to endocrinopathy in iron overloaded patients with sickle cell disease and thalassemia. Bone. 2008 Jul; 43(1):162-168. PMID: 18430624.
      Citations: 27     Fields:    Translation:Humans
    52. Porter J, Galanello R, Saglio G, Neufeld EJ, Vichinsky E, Cappellini MD, Olivieri N, Piga A, Cunningham MJ, Souli?res D, Gattermann N, Tchernia G, Maertens J, Giardina P, Kwiatkowski J, Quarta G, Jeng M, Forni GL, Stadler M, Cario H, Debusscher L, Della Porta M, Cazzola M, Greenberg P, Alimena G, Rabault B, Gathmann I, Ford JM, Alberti D, Rose C. Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): a 1-yr prospective study. Eur J Haematol. 2008 Feb; 80(2):168-76. PMID: 18028431.
      Citations: 79     Fields:    Translation:Humans
    53. Harmatz P, Grady RW, Dragsten P, Vichinsky E, Giardina P, Madden J, Jeng M, Miller B, Hanson G, Hedlund B. Phase Ib clinical trial of starch-conjugated deferoxamine (40SD02): a novel long-acting iron chelator. Br J Haematol. 2007 Aug; 138(3):374-81. PMID: 17614825.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    54. Gardenghi S, Marongiu MF, Ramos P, Guy E, Breda L, Chadburn A, Liu Y, Amariglio N, Rechavi G, Rachmilewitz EA, Breuer W, Cabantchik ZI, Wrighting DM, Andrews NC, de Sousa M, Giardina PJ, Grady RW, Rivella S. Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin. Blood. 2007 Jun 01; 109(11):5027-35. PMID: 17299088.
      Citations: 138     Fields:    Translation:AnimalsCells
    55. Sadelain M, Boulad F, Galanello R, Giardina P, Locatelli F, Maggio A, Rivella S, Riviere I, Tisdale J. Therapeutic options for patients with severe beta-thalassemia: the need for globin gene therapy. Hum Gene Ther. 2007 Jan; 18(1):1-9. PMID: 17173507.
      Citations: 19     Fields:    Translation:HumansAnimals
    56. Cappellini MD, Cohen A, Piga A, Bejaoui M, Perrotta S, Agaoglu L, Aydinok Y, Kattamis A, Kilinc Y, Porter J, Capra M, Galanello R, Fattoum S, Drelichman G, Magnano C, Verissimo M, Athanassiou-Metaxa M, Giardina P, Kourakli-Symeonidis A, Janka-Schaub G, Coates T, Vermylen C, Olivieri N, Thuret I, Opitz H, Ressayre-Djaffer C, Marks P, Alberti D. A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia. Blood. 2006 May 01; 107(9):3455-62. PMID: 16352812.
      Citations: 184     Fields:    Translation:HumansCTClinical Trials
    57. Vogiatzi MG, Autio KA, Mait JE, Schneider R, Lesser M, Giardina PJ. Low bone mineral density in adolescents with beta-thalassemia. Ann N Y Acad Sci. 2005; 1054:462-6. PMID: 16339698.
      Citations: 17     Fields:    Translation:Humans
    58. Breda L, Gardenghi S, Guy E, Rachmilewitz EA, Weizer-Stern O, Adamsky K, Amariglio N, Rechavi G, Giardina PJ, Grady RW, Rivella S. Exploring the role of hepcidin, an antimicrobial and iron regulatory peptide, in increased iron absorption in beta-thalassemia. Ann N Y Acad Sci. 2005; 1054:417-22. PMID: 16339690.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    59. Vogiatzi MG, Autio KA, Schneider R, Giardina PJ. Low bone mass in prepubertal children with thalassemia major: insights into the pathogenesis of low bone mass in thalassemia. J Pediatr Endocrinol Metab. 2004 Oct; 17(10):1415-21. PMID: 15526720.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    60. Nisbet-Brown E, Olivieri NF, Giardina PJ, Grady RW, Neufeld EJ, S?chaud R, Krebs-Brown AJ, Anderson JR, Alberti D, Sizer KC, Nathan DG. Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: a randomised, double-blind, placebo-controlled, dose-escalation trial. Lancet. 2003 May 10; 361(9369):1597-602. PMID: 12747879.
      Citations: 75     Fields:    Translation:HumansCTClinical Trials
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