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Nikolaos Kakouros MBBS MD(Res) PhD FRCP FACC FSC

TitleAssociate Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentMedicine
AddressUniversity of Massachusetts Medical School
55 Lake Avenue North, H2-460
Worcester MA 01655
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentMedicine
    DivisionCardiovascular Medicine


    Collapse Biography 
    Collapse education and training
    University of London, London, , United KingdomBSNeuroscience
    Medical School of University of Athens, Athens, , GreecePHDCardiovascular Science
    University of London, London, , United KingdomMBBSMedicine and Surgery
    University of London, London, , United KingdomMDResearch

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kundu A, Sardar P, Malhotra R, Qureshi WT, Kakouros N. Cardiovascular outcomes with transcatheter vs. surgical aortic valve replacement in low-risk patients: An updated meta-analysis of randomized controlled trials. Cardiovasc Revasc Med. 2019 Aug 15. PMID: 31669113.
      View in: PubMed
    2. Kassas I, Nagy A, Alonso A, Akhter MW, Smith CS, Ahmed M, Hafiz AM, Walker J, Kakouros N. Orbital Atherectomy for Calcific Coronary Artery Disease in Patients With Severe Aortic Stenosis: A Safety and Feasibility Study. J Invasive Cardiol. 2019 Jul; 31(7):E205-E210. PMID: 31257215.
      View in: PubMed
    3. Kundu A, Sardar P, Kakouros N, Fisher DZ. Rebuttal: Response to letter by Desch et al. regarding "Outcomes of multivessel vs. culprit lesion-only percutaneous coronary intervention in patients with acute myocardial infarction complicated by cardiogenic shock: Evidence from an updated meta-analysis". Catheter Cardiovasc Interv. 2019 May 15. PMID: 31090240.
      View in: PubMed
    4. Tachjian A, Sanghai SR, Stencel J, Parker MW, Kakouros N, Aurigemma GP. Estimation of Mean Left Atrial Pressure in Patients with Acute Coronary Syndromes: A Doppler Echocardiographic and Cardiac Catheterization Study. J Am Soc Echocardiogr. 2019 Jan 16. PMID: 30660349.
      View in: PubMed
    5. Kundu A, Sardar P, Kakouros N, Malhotra R, Kolte D, Feldman DN, Abbott JD, Fisher DZ. Outcomes of multivessel vs culprit lesion-only percutaneous coronary intervention in patients with acute myocardial infarction complicated by cardiogenic shock: Evidence from an updated meta-analysis. Catheter Cardiovasc Interv. 2018 Dec 28. PMID: 30593731.
      View in: PubMed
    6. Iskandar A, Mowakeaa S, Sardana M, Fitzgibbons TP, Tighe DA, Parker MW, Kakouros N, McManus D, Aurigemma GP. The presbycardia phenotype: Cardiac remodeling and valvular degeneration in nonagenarians. Echocardiography. 2018 Nov 15. PMID: 30431175.
      View in: PubMed
    7. Hendrix RJ, Bello RA, Flahive JM, Kakouros N, Aurigemma GP, Keaney JF, Hoffman W, Vassileva CM. Mitral valve repair vs replacement in elderly with degenerative disease: Analysis of the STS Adult Cardiac Surgery Database. Ann Thorac Surg. 2018 Oct 26. PMID: 30612990.
      View in: PubMed
    8. McNeely C, Zajarias A, Fohtung R, Kakouros N, Walker J, Robbs R, Markwell S, Vassileva CM. Racial Comparisons of the Outcomes of Transcatheter and Surgical Aortic Valve Implantation Using the Medicare Database. Am J Cardiol. 2018 Aug 01; 122(3):440-445. PMID: 30201109.
      View in: PubMed
    9. Taleb A, Parikh G, Kakouros N. Longitudinal Deformation of Distal Edge in a New-Generation Stent Caused by Guidewire Entrapment. Tex Heart Inst J. 2018 02; 45(1):45-47. PMID: 29556153.
      View in: PubMed
    10. Kakouros N, Kakouros SN. Pacemaker malfunction risks within the electromagnetically rich hospital environment. Hellenic J Cardiol. 2017 Nov 14. PMID: 29154816.
      View in: PubMed
    11. Kakouros N, Gluckman TJ, Conte JV, Kickler TS, Laws K, Barton BA, Rade JJ. Differential Impact of Serial Measurement of Nonplatelet Thromboxane Generation on Long-Term Outcome After Cardiac Surgery. J Am Heart Assoc. 2017 Nov 02; 6(11). PMID: 29097390.
      View in: PubMed
    12. Hafiz AM, Smith C, Kakouros N. The GuideLiner-Sleeve Technique: A Novel Technique for High-Risk PCI Using Two Left Main Guides for Orbital Atherectomy of Two-Vessel Calcified Ostial Coronary Artery Disease. J Invasive Cardiol. 2017 Nov; 29(11):E159-E160. PMID: 29086733.
      View in: PubMed
    13. Alexander B, Angaramo G, Walz JM, Kakouros N, Moiz Hafiz A, Walker J, Krapchev P. A Novel Approach to Managing Trans-Subclavian Transcatheter Aortic Valve Replacement With Regional Anesthesia. J Cardiothorac Vasc Anesth. 2018 Jun; 32(3):1391-1393. PMID: 29128481.
      View in: PubMed
    14. Parikh GR, Peter E, Kakouros N. Complex Coronary Hemodynamics - Simple Analog Modelling as an Educational Tool. Open Med Inform J. 2017; 11:12-19. PMID: 28932342.
      View in: PubMed
    15. Hafiz AM, Medranda GA, Kakouros N, Patel J, Kahan J, Gubernikoff G, Ray B, Paruchuri V, DeLeon J, Marzo K, Calixte R, Gaztanaga J. Is intra-procedure three-dimensional transesophageal echocardiogram an alternative to preprocedure multidetector computed tomography for the measurement of the aortic annulus in patients undergoing transcatheter aortic valve replacement? Echocardiography. 2017 Aug; 34(8):1195-1202. PMID: 28722306.
      View in: PubMed
    16. Hafiz AM, Shih J, Kakouros N. Transcatheter Tricuspid Valve Replacement in Orthotopic Heart Transplant. J Invasive Cardiol. 2017 Jun; 29(6):E75-E76. PMID: 28570244.
      View in: PubMed
    17. Alame AJ, Karatasakis A, Karacsonyi J, Danek BA, Sorajja P, Gössl M, Garcia S, Jneid H, Kakouros N, Martinez-Parachini JR, Resendes E, Kalsaria P, Roesle M, Rangan BV, Banerjee S, Brilakis ES. Comparison of the American College of Cardiology/American Heart Association and the European Society of Cardiology Guidelines for the Management of Patients With Valvular Heart Disease. J Invasive Cardiol. 2017 Apr 15. PMID: 28420803.
      View in: PubMed
    18. Sardar P, Kundu A, Chatterjee S, Feldman DN, Owan T, Kakouros N, Nairooz R, Pape LA, Feldman T, Dawn Abbott J, Elmariah S. Transcatheter versus surgical aortic valve replacement in intermediate-risk patients: Evidence from a meta-analysis. Catheter Cardiovasc Interv. 2017 Apr 11. PMID: 28398671.
      View in: PubMed
    19. Rana G, Malhotra R, Sharma A, Kakouros N. Percutaneous Valvuloplasty for Bioprosthetic Tricuspid Valve Stenosis. Tex Heart Inst J. 2017 Feb; 44(1):43-49. PMID: 28265212.
      View in: PubMed
    20. Mowakeaa S, Snyder B, Kakouros N. Use of orbital atherectomy in acute myocardial infarction via the transradial approach. Interv Med Appl Sci. 2016 Dec; 8(4):178-180. PMID: 28180008.
      View in: PubMed
    21. Kakouros N. Storage of Fractional Flow Reserve Hemodynamic Waveforms Using Semantic Extension of the DICOM Standard. J Digit Imaging. 2016 Jun; 29(3):314-20. PMID: 26527469.
      View in: PubMed
    22. Kakouros N, Nazarian SM, Stadler PB, Kickler TS, Rade JJ. Risk Factors for Nonplatelet Thromboxane Generation After Coronary Artery Bypass Graft Surgery. J Am Heart Assoc. 2016 Mar 15; 5(3):e002615. PMID: 27068626.
      View in: PubMed
    23. Mowakeaa S, Iskandar A, Kakouros N. Neoatherosclerosis in Very Late Stenosis of Bare Metal Stent by Optical Coherence Tomography. Case Rep Cardiol. 2016; 2016:1652065. PMID: 27034852.
      View in: PubMed
    24. Kakouros N, Rade JJ. Role of Fractional-Flow Reserve in Guiding Percutaneous Revascularization in Stable Coronary Artery Disease. Curr Atheroscler Rep. 2015 Sep; 17(9):52. PMID: 26202795.
      View in: PubMed
    25. Kakouros NS, Kakouros SN. Clinical Assessment in Acute Heart Failure. Hellenic J Cardiol. 2015 Jul-Aug; 56(4):285-301. PMID: 26233768.
      View in: PubMed
    26. Rana G, Shih J, Kakouros N. Percutaneous transcatheter balloon valvuloplasty for bioprosthetic tricuspid valve stenosis in a patient with orthotopic heart transplant. J Invasive Cardiol. 2015 Mar; 27(3):E40-1. PMID: 25740974.
      View in: PubMed
    27. Henninger N, Haussen DC, Kakouros N, Selim M, Searls DE, Kumar S, Schlaug G, Caplan LR. QTc-prolongation in posterior circulation stroke. Neurocrit Care. 2013 Oct; 19(2):167-75. PMID: 23860666.
      View in: PubMed
    28. Kakouros N. Oral anticoagulation and implantation of cardiac rhythm management devices: is heparin a bridge too far? Hellenic J Cardiol. 2013 Mar-Apr; 54(2):150-1. PMID: 23557618.
      View in: PubMed
    29. Kakouros N. Distributed storage healthcare - the basis of a planet-wide public health care network. Open Med Inform J. 2013; 7:1-7. PMID: 23459171.
      View in: PubMed
    30. Kakouros N, Rybicki FJ, Mitsouras D, Miller JM. Coronary pressure-derived fractional flow reserve in the assessment of coronary artery stenoses. Eur Radiol. 2013 Apr; 23(4):958-67. PMID: 23179519.
      View in: PubMed
    31. Kapur NK, Bian C, Lin E, Deming CB, Sperry JL, Hansen BS, Kakouros N, Rade JJ. Inhibition of transforming growth factor-ß restores endothelial thromboresistance in vein grafts. J Vasc Surg. 2011 Oct; 54(4):1117-1123.e1. PMID: 21803524.
      View in: PubMed
    32. Kakouros N, Patel SJ, Redwood S, Wasan BS. Triple-vessel percutaneous coronary revascularization in situs inversus dextrocardia. Cardiol Res Pract. 2010; 2010:606327. PMID: 20631900.
      View in: PubMed
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