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Nikolaos Kakouros MBBS MD(Res) PhD FRCP FACC FSC

TitleAssociate Professor
InstitutionUMass Chan Medical School
DepartmentMedicine
AddressUMass Chan Medical School
55 Lake Avenue North H2-460
Worcester MA 01655
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMedicine
    DivisionCardiovascular Medicine


    Collapse Biography 
    Collapse education and training
    University of London, London, , United KingdomBSNeuroscience
    Medical School of University of Athens, Athens, , GreecePHDCardiovascular Science
    University of London, London, , United KingdomMBBSMedicine and Surgery
    University of London, London, , United KingdomMDResearch

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mir T, Qureshi WT, Uddin M, Soubani A, Saydain G, Rab T, Kakouros N. Predictors and outcomes of cardiac arrest in the emergency department and in-patient settings in the United States (2016-2018). Resuscitation. 2022 01; 170:100-106. PMID: 34801637.
      Citations:    Fields:    Translation:Humans
    2. Wilkie GL, Qureshi WT, O'Day KW, Aurigemma GP, Goldberg RJ, Amjad W, Alqalyoobi S, Kakouros N, Lauring JR, Leftwich HK, Harrington CM. Cardiac and Obstetric Outcomes Associated With Mitral Valve Prolapse. Am J Cardiol. 2022 01 01; 162:150-155. PMID: 34689956.
      Citations:    Fields:    Translation:Humans
    3. Mir T, Qureshi WT, Uddin M, Shafi O, Sheikh M, Kakouros N. Non-ST elevation myocardial infarction and cardiac arrest: The United States Nationwide Emergency Department Sample. J Cardiol. 2022 01; 79(1):98-104. PMID: 34470713.
      Citations:    Fields:    Translation:Humans
    4. Qureshi WT, Kundu A, Mir T, Khan A, Anwaruddin S, Sattar Y, Ogunsua A, Dutta A, Majeed CN, Walker J, Kakouros N. Meta-analysis of minimalist versus standard care approach for transcatheter aortic valve replacement. Expert Rev Cardiovasc Ther. 2021 Jun; 19(6):565-574. PMID: 33896312.
      Citations:    Fields:    Translation:Humans
    5. Kundu A, Ogunsua AA, Walker J, Qureshi WT, Kakouros N. Bilateral vas deferens calcification in a patient with multi-vessel coronary artery disease and severe aortic stenosis: linking infertility with cardiovascular disease. J Community Hosp Intern Med Perspect. 2021; 11(3):376-378. PMID: 34234910.
      Citations:    
    6. Soueid AE, Kassas I, Rade J, Kakouros N. Evaluation of a Real-World In-Hospital Antiplatelet-Switching Strategy Following Coronary Interventions: The SWITCH Study. J Invasive Cardiol. 2021 04; 33(4):E263-E268. PMID: 33794478.
      Citations:    Fields:    Translation:Humans
    7. Choudhary KV, Kakouros N, Aurigemma GP, Parker MW, Fitzgibbons T. Differentiating Pseudo Versus True Aortic Stenosis in Patients Without Contractile Reserve: A Diagnostic Dilemma. Cureus. 2021 Mar 24; 13(3):e14086. PMID: 33903843.
      Citations:    
    8. Qureshi WT, Parker M, Walker J, Kakouros N. Equipment entrapment during redo-TAVR with successful BASILICA procedure. Catheter Cardiovasc Interv. 2021 08 01; 98(2):E320-E323. PMID: 33484070.
      Citations:    Fields:    Translation:Humans
    9. Qureshi WT, Ogunsua AA, Kundu A, Sattar Y, Fisher DZ, Kakouros N. Angled Microcatheter Assisted Antegrade Dissection Re-Entry Technique for Tortuous Totally Occluded Coronary Arteries. Cardiovasc Revasc Med. 2021 07; 28S:127-131. PMID: 33500228.
      Citations:    Fields:    Translation:Humans
    10. Qureshi WT, Kakouros N, Fahed J, Rade JJ. Comparison of Prevalence, Presentation, and Prognosis of Acute Coronary Syndromes in ?35 years, 36 - 54 years, and ? 55 years Patients. Am J Cardiol. 2021 02 01; 140:1-6. PMID: 33166493.
      Citations: 1     Fields:    Translation:Humans
    11. Qureshi WT, Malhotra R, Schmidlin EJ, Ahmed M, Kundu A, Hafiz AM, Walker J, Kakouros N. Evaluation of ECG-gated and Fast Low-Angle Shot (FLASH) Dual Source Computed Tomography Scanning Protocols for Transcatheter Aortic Valve Replacement. Acad Radiol. 2021 12; 28(12):1669-1674. PMID: 32972842.
      Citations:    Fields:    Translation:Humans
    12. Qureshi WT, Al-Drugh S, Ogunsua A, Harrington C, Aman W, Balsam L, Kar B, Aurigemma G, Kundu A, Kaur N, Smith C, Fisher D, Rade J, Kakouros N. Post-Myocardial Infarction Complications During the COVID-19 Pandemic - A Case Series. Cardiovasc Revasc Med. 2021 07; 28S:253-258. PMID: 32863191.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    13. Kanei Y, Qureshi W, Walker J, Kakouros N. Guide Extension-Assisted Stent Implantation at Ostial Right Coronary Artery Creating Stent Tunnel During Transcatheter Aortic Valve Replacement. Cardiovasc Revasc Med. 2020 11; 21(11S):50-53. PMID: 32473909.
      Citations:    Fields:    Translation:Humans
    14. Hafiz AM, Perras M, Kakouros N. Acquired Coronary Fenestration. J Invasive Cardiol. 2019 Dec; 31(12):E396. PMID: 31786535.
      Citations:    Fields:    Translation:Humans
    15. Kundu A, Sardar P, Malhotra R, Qureshi WT, Kakouros N. Cardiovascular Outcomes with Transcatheter vs. Surgical Aortic Valve Replacement in Low-Risk Patients: An Updated Meta-Analysis of Randomized Controlled Trials. Cardiovasc Revasc Med. 2020 04; 21(4):453-460. PMID: 31669113.
      Citations: 1     Fields:    Translation:Humans
    16. Kassas I, Nagy A, Alonso A, Akhter MW, Smith CS, Ahmed M, Hafiz AM, Walker J, Kakouros N. Orbital Atherectomy for Calcific Coronary Artery Disease in Patients With Severe Aortic Stenosis: A Safety and Feasibility Study. J Invasive Cardiol. 2019 Jul; 31(7):E205-E210. PMID: 31257215.
      Citations:    Fields:    Translation:Humans
    17. Kundu A, Sardar P, Kakouros N, Fisher DZ. Rebuttal: Response to letter by Desch et al. regarding "Outcomes of multivessel vs. culprit lesion-only percutaneous coronary intervention in patients with acute myocardial infarction complicated by cardiogenic shock: Evidence from an updated meta-analysis". Catheter Cardiovasc Interv. 2019 11 15; 94(6):896-897. PMID: 31090240.
      Citations:    Fields:    Translation:Humans
    18. Tachjian A, Sanghai SR, Stencel J, Parker MW, Kakouros N, Aurigemma GP. Estimation of Mean Left Atrial Pressure in Patients with Acute Coronary Syndromes: A Doppler Echocardiographic and Cardiac Catheterization Study. J Am Soc Echocardiogr. 2019 03; 32(3):365-374.e1. PMID: 30660349.
      Citations: 1     Fields:    Translation:Humans
    19. Kundu A, Sardar P, Kakouros N, Malhotra R, Kolte D, Feldman DN, Abbott JD, Fisher DZ. Outcomes of multivessel vs culprit lesion-only percutaneous coronary intervention in patients with acute myocardial infarction complicated by cardiogenic shock: Evidence from an updated meta-analysis. Catheter Cardiovasc Interv. 2019 07 01; 94(1):70-81. PMID: 30593731.
      Citations:    Fields:    Translation:Humans
    20. Iskandar A, Mowakeaa S, Sardana M, Fitzgibbons TP, Tighe DA, Parker MW, Kakouros N, McManus D, Aurigemma GP. The presbycardia phenotype: Cardiac remodeling and valvular degeneration in nonagenarians. Echocardiography. 2018 12; 35(12):1974-1981. PMID: 30431175.
      Citations: 2     Fields:    Translation:Humans
    21. Hendrix RJ, Bello RA, Flahive JM, Kakouros N, Aurigemma GP, Keaney JF, Hoffman W, Vassileva CM. Mitral Valve Repair Versus Replacement in Elderly With Degenerative Disease: Analysis of the STS Adult Cardiac Surgery Database. Ann Thorac Surg. 2019 03; 107(3):747-753. PMID: 30612990.
      Citations: 4     Fields:    Translation:Humans
    22. McNeely C, Zajarias A, Fohtung R, Kakouros N, Walker J, Robbs R, Markwell S, Vassileva CM. Racial Comparisons of the Outcomes of Transcatheter and Surgical Aortic Valve Implantation Using the Medicare Database. Am J Cardiol. 2018 08 01; 122(3):440-445. PMID: 30201109.
      Citations: 5     Fields:    Translation:Humans
    23. Taleb A, Parikh G, Kakouros N. Longitudinal Deformation of Distal Edge in a New-Generation Stent Caused by Guidewire Entrapment. Tex Heart Inst J. 2018 02; 45(1):45-47. PMID: 29556153.
      Citations:    Fields:    Translation:Humans
    24. Kakouros N, Kakouros SN. Pacemaker malfunction risks within the electromagnetically rich hospital environment. Hellenic J Cardiol. 2018 Jul - Aug; 59(4):247-248. PMID: 29154816.
      Citations:    Fields:    Translation:Humans
    25. Kakouros N, Gluckman TJ, Conte JV, Kickler TS, Laws K, Barton BA, Rade JJ. Differential Impact of Serial Measurement of Nonplatelet Thromboxane Generation on Long-Term Outcome After Cardiac Surgery. J Am Heart Assoc. 2017 Nov 02; 6(11). PMID: 29097390.
      Citations:    Fields:    Translation:Humans
    26. Hafiz AM, Smith C, Kakouros N. The GuideLiner-Sleeve Technique: A Novel Technique for High-Risk PCI Using Two Left Main Guides for Orbital Atherectomy of Two-Vessel Calcified Ostial Coronary Artery Disease. J Invasive Cardiol. 2017 Nov; 29(11):E159-E160. PMID: 29086733.
      Citations:    Fields:    Translation:Humans
    27. Alexander B, Angaramo G, Walz JM, Kakouros N, Moiz Hafiz A, Walker J, Krapchev P. A Novel Approach to Managing Trans-Subclavian Transcatheter Aortic Valve Replacement With Regional Anesthesia. J Cardiothorac Vasc Anesth. 2018 06; 32(3):1391-1393. PMID: 29128481.
      Citations: 1     Fields:    Translation:Humans
    28. Parikh GR, Peter E, Kakouros N. Complex Coronary Hemodynamics - Simple Analog Modelling as an Educational Tool. Open Med Inform J. 2017; 11:12-19. PMID: 28932342.
      Citations:    
    29. Hafiz AM, Medranda GA, Kakouros N, Patel J, Kahan J, Gubernikoff G, Ray B, Paruchuri V, DeLeon J, Marzo K, Calixte R, Gaztanaga J. Is intra-procedure three-dimensional transesophageal echocardiogram an alternative to preprocedure multidetector computed tomography for the measurement of the aortic annulus in patients undergoing transcatheter aortic valve replacement? Echocardiography. 2017 Aug; 34(8):1195-1202. PMID: 28722306.
      Citations: 3     Fields:    Translation:Humans
    30. Hafiz AM, Shih J, Kakouros N. Transcatheter Tricuspid Valve Replacement in Orthotopic Heart Transplant. J Invasive Cardiol. 2017 Jun; 29(6):E75-E76. PMID: 28570244.
      Citations:    Fields:    Translation:Humans
    31. Alame AJ, Karatasakis A, Karacsonyi J, Danek BA, Sorajja P, Gössl M, Garcia S, Jneid H, Kakouros N, Martinez-Parachini JR, Resendes E, Kalsaria P, Roesle M, Rangan BV, Banerjee S, Brilakis ES. Comparison of the American College of Cardiology/American Heart Association and the European Society of Cardiology Guidelines for the Management of Patients With Valvular Heart Disease. J Invasive Cardiol. 2017 Sep; 29(9):320-326. PMID: 28420803.
      Citations: 3     Fields:    Translation:Humans
    32. Sardar P, Kundu A, Chatterjee S, Feldman DN, Owan T, Kakouros N, Nairooz R, Pape LA, Feldman T, Dawn Abbott J, Elmariah S. Transcatheter versus surgical aortic valve replacement in intermediate-risk patients: Evidence from a meta-analysis. Catheter Cardiovasc Interv. 2017 Sep 01; 90(3):504-515. PMID: 28398671.
      Citations: 4     Fields:    Translation:Humans
    33. Rana G, Malhotra R, Sharma A, Kakouros N. Percutaneous Valvuloplasty for Bioprosthetic Tricuspid Valve Stenosis. Tex Heart Inst J. 2017 Feb; 44(1):43-49. PMID: 28265212.
      Citations: 1     Fields:    Translation:Humans
    34. Mowakeaa S, Snyder B, Kakouros N. Use of orbital atherectomy in acute myocardial infarction via the transradial approach. Interv Med Appl Sci. 2016 Dec; 8(4):178-180. PMID: 28180008.
      Citations:    
    35. Kakouros N. Storage of Fractional Flow Reserve Hemodynamic Waveforms Using Semantic Extension of the DICOM Standard. J Digit Imaging. 2016 06; 29(3):314-20. PMID: 26527469.
      Citations:    Fields:    Translation:Humans
    36. Kakouros N, Nazarian SM, Stadler PB, Kickler TS, Rade JJ. Risk Factors for Nonplatelet Thromboxane Generation After Coronary Artery Bypass Graft Surgery. J Am Heart Assoc. 2016 Mar 15; 5(3):e002615. PMID: 27068626.
      Citations: 4     Fields:    Translation:HumansCells
    37. Mowakeaa S, Iskandar A, Kakouros N. Neoatherosclerosis in Very Late Stenosis of Bare Metal Stent by Optical Coherence Tomography. Case Rep Cardiol. 2016; 2016:1652065. PMID: 27034852.
      Citations:    
    38. Kakouros N, Rade JJ. Role of Fractional-Flow Reserve in Guiding Percutaneous Revascularization in Stable Coronary Artery Disease. Curr Atheroscler Rep. 2015 Sep; 17(9):52. PMID: 26202795.
      Citations: 2     Fields:    Translation:Humans
    39. Kakouros NS, Kakouros SN. Clinical Assessment in Acute Heart Failure. Hellenic J Cardiol. 2015 Jul-Aug; 56(4):285-301. PMID: 26233768.
      Citations: 1     Fields:    Translation:Humans
    40. Rana G, Shih J, Kakouros N. Percutaneous transcatheter balloon valvuloplasty for bioprosthetic tricuspid valve stenosis in a patient with orthotopic heart transplant. J Invasive Cardiol. 2015 Mar; 27(3):E40-1. PMID: 25740974.
      Citations: 1     Fields:    Translation:Humans
    41. Henninger N, Haussen DC, Kakouros N, Selim M, Searls DE, Kumar S, Schlaug G, Caplan LR. QTc-prolongation in posterior circulation stroke. Neurocrit Care. 2013 Oct; 19(2):167-75. PMID: 23860666.
      Citations: 5     Fields:    Translation:Humans
    42. Kakouros N. Oral anticoagulation and implantation of cardiac rhythm management devices: is heparin a bridge too far? Hellenic J Cardiol. 2013 Mar-Apr; 54(2):150-1. PMID: 23557618.
      Citations:    Fields:    Translation:Humans
    43. Kakouros N. Distributed storage healthcare - the basis of a planet-wide public health care network. Open Med Inform J. 2013; 7:1-7. PMID: 23459171.
      Citations:    
    44. Kakouros N, Rybicki FJ, Mitsouras D, Miller JM. Coronary pressure-derived fractional flow reserve in the assessment of coronary artery stenoses. Eur Radiol. 2013 Apr; 23(4):958-67. PMID: 23179519.
      Citations: 8     Fields:    Translation:Humans
    45. Kapur NK, Bian C, Lin E, Deming CB, Sperry JL, Hansen BS, Kakouros N, Rade JJ. Inhibition of transforming growth factor-? restores endothelial thromboresistance in vein grafts. J Vasc Surg. 2011 Oct; 54(4):1117-1123.e1. PMID: 21803524.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    46. Kakouros N, Patel SJ, Redwood S, Wasan BS. Triple-vessel percutaneous coronary revascularization in situs inversus dextrocardia. Cardiol Res Pract. 2010; 2010:606327. PMID: 20631900.
      Citations:    
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