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Janice A Dominov PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentNeurology
AddressUMass Chan Medical School
368 Plantation Street AS6.1059
Worcester MA 01605
Phone774-455-3751
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentNeurology

    InstitutionT.H. Chan School of Medicine
    DepartmentNeuroNexus Institute

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentNeuroscience


    Collapse Biography 
    Collapse education and training
    University of Rhode Island, Kingston, RI, United StatesBSMicrobiology
    Case Western Reserve University, Cleveland, OH, United StatesPHDBiology

    Collapse Overview 
    Collapse Summary
    Investigates neuromuscular disease with an emphasis on muscular dystrophies, cell death mechanisms, inflammatory pathway regulation and therapeutics for muscular dystrophies.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fontelonga T, Hall AJ, Brown JL, Jung YL, Alexander MS, Dominov JA, Mouly V, Vieira N, Zatz M, Vainzof M, Gussoni E. Tetraspanin CD82 Associates with Trafficking Vesicle in Muscle Cells and Binds to Dysferlin and Myoferlin. Adv Biol (Weinh). 2023 12; 7(12):e2300157. PMID: 37434585.
      Citations:    Fields:    Translation:HumansCells
    2. Dominov JA, Madigan LA, Whitt JP, Rademacher KL, Webster KM, Zhang H, Banno H, Tang S, Zhang Y, Wightman N, Shychuck EM, Page J, Weiss A, Kelly K, Kucukural A, Brodsky MH, Jaworski A, Fallon JR, Lipscombe D, Brown RH. Up-regulation of cholesterol synthesis pathways and limited neurodegeneration in a knock-in Sod1 mutant mouse model of ALS. bioRxiv. 2023 May 05. PMID: 37205335.
      Citations:    
    3. Dominov JA, Uyan ?, McKenna-Yasek D, Nallamilli BRR, Kergourlay V, Bartoli M, Levy N, Hudson J, Evangelista T, Lochmuller H, Krahn M, Rufibach L, Hegde M, Brown RH. Correction of pseudoexon splicing caused by a novel intronic dysferlin mutation. Ann Clin Transl Neurol. 2019 Apr; 6(4):642-654. PMID: 31019989.
      Citations: 11     Fields:    Translation:HumansCells
    4. Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, Van der Spek RA, Pliner HA, Smith BN, Marangi G, Topp SD, Abramzon Y, Gkazi AS, Eicher JD, Kenna A, Mora G, Calvo A, Mazzini L, Riva N, Mandrioli J, Caponnetto C, Battistini S, Volanti P, La Bella V, Conforti FL, Borghero G, Messina S, Simone IL, Trojsi F, Salvi F, Logullo FO, D'Alfonso S, Corrado L, Capasso M, Ferrucci L, Moreno CAM, Kamalakaran S, Goldstein DB, Gitler AD, Harris T, Myers RM, Phatnani H, Musunuri RL, Evani US, Abhyankar A, Zody MC, Kaye J, Finkbeiner S, Wyman SK, LeNail A, Lima L, Fraenkel E, Svendsen CN, Thompson LM, Van Eyk JE, Berry JD, Miller TM, Kolb SJ, Cudkowicz M, Baxi E, Benatar M, Taylor JP, Rampersaud E, Wu G, Wuu J, Lauria G, Verde F, Fogh I, Tiloca C, Comi GP, Sorar? G, Cereda C, Corcia P, Laaksovirta H, Myllykangas L, Jansson L, Valori M, Ealing J, Hamdalla H, Rollinson S, Pickering-Brown S, Orrell RW, Sidle KC, Malaspina A, Hardy J, Singleton AB, Johnson JO, Arepalli S, Sapp PC, McKenna-Yasek D, Polak M, Asress S, Al-Sarraj S, King A, Troakes C, Vance C, de Belleroche J, Baas F, Ten Asbroek ALMA, Mu?oz-Blanco JL, Hernandez DG, Ding J, Gibbs JR, Scholz SW, Floeter MK, Campbell RH, Landi F, Bowser R, Pulst SM, Ravits JM, MacGowan DJL, Kirby J, Pioro EP, Pamphlett R, Broach J, Gerhard G, Dunckley TL, Brady CB, Kowall NW, Troncoso JC, Le Ber I, Mouzat K, Lumbroso S, Heiman-Patterson TD, Kamel F, Van Den Bosch L, Baloh RH, Strom TM, Meitinger T, Shatunov A, Van Eijk KR, de Carvalho M, Kooyman M, Middelkoop B, Moisse M, McLaughlin RL, Van Es MA, Weber M, Boylan KB, Van Blitterswijk M, Rademakers R, Morrison KE, Basak AN, Mora JS, Drory VE, Shaw PJ, Turner MR, Talbot K, Hardiman O, Williams KL, Fifita JA, Nicholson GA, Blair IP, Rouleau GA, Esteban-P?rez J, Garc?a-Redondo A, Al-Chalabi A, Rogaeva E, Zinman L, Ostrow LW, Maragakis NJ, Rothstein JD, Simmons Z, Cooper-Knock J, Brice A, Goutman SA, Feldman EL, Gibson SB, Taroni F, Ratti A, Gellera C, Van Damme P, Robberecht W, Fratta P, Sabatelli M, Lunetta C, Ludolph AC, Andersen PM, Weishaupt JH, Camu W, Trojanowski JQ, Van Deerlin VM, Brown RH, van den Berg LH, Veldink JH, Harms MB, Glass JD, Stone DJ, Tienari P, Silani V, Chi? A, Shaw CE, Traynor BJ, Landers JE. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 2018 03 21; 97(6):1267-1288. PMID: 29566793.
      Citations: 304     Fields:    Translation:HumansCells
    5. Dominov JA, Uyan ?, Sapp PC, McKenna-Yasek D, Nallamilli BR, Hegde M, Brown RH. Reply to comment on: A novel dysferlin mutant pseudoexon bypassed with antisense oligonucleotides. Ann Clin Transl Neurol. 2015 Jul; 2(7):785. PMID: 26290895.
      Citations:    Fields:    
    6. Dominov JA, Uyan O, Sapp PC, McKenna-Yasek D, Nallamilli BR, Hegde M, Brown RH. A novel dysferlin mutant pseudoexon bypassed with antisense oligonucleotides. Ann Clin Transl Neurol. 2014 Sep; 1(9):703-20. PMID: 25493284.
      Citations: 15     Fields:    
    7. Rutkowski A, B?nnemann C, Brown S, Thorsteinsd?ttir S, Dominov J, Ruegg MA, Matter ML, Guttridge D, Crosbie-Watson RH, Kardon G, Nagaraju K, Girgenrath M, Burkin DJ. Report on the Myomatrix Conference April 22-24, 2012, University of Nevada, Reno, Nevada, USA. Neuromuscul Disord. 2013 Feb; 23(2):188-91. PMID: 22800409.
      Citations: 1     Fields:    Translation:HumansCells
    8. Jeudy S, Wardrop KE, Alessi A, Dominov JA. Bcl-2 inhibits the innate immune response during early pathogenesis of murine congenital muscular dystrophy. PLoS One. 2011; 6(8):e22369. PMID: 21850221.
      Citations: 6     Fields:    Translation:Animals
    9. Pavlath GK, Dominov JA, Kegley KM, Miller JB. Regeneration of transgenic skeletal muscles with altered timing of expression of the basic helix-loop-helix muscle regulatory factor MRF4. Am J Pathol. 2003 May; 162(5):1685-91. PMID: 12707053.
      Citations: 15     Fields:    Translation:AnimalsCells
    10. Dominov JA, Houlihan-Kawamoto CA, Swap CJ, Miller JB. Pro- and anti-apoptotic members of the Bcl-2 family in skeletal muscle: a distinct role for Bcl-2 in later stages of myogenesis. Dev Dyn. 2001 Jan; 220(1):18-26. PMID: 11146504.
      Citations: 16     Fields:    Translation:AnimalsCells
    11. Miller JB, Schaefer L, Dominov JA. Seeking muscle stem cells. Curr Top Dev Biol. 1999; 43:191-219. PMID: 9891887.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    12. Dominov JA, Miller JB. POU homeodomain genes and myogenesis. Dev Genet. 1996; 19(2):108-18. PMID: 8900043.
      Citations: 5     Fields:    Translation:AnimalsCells
    13. Kachinsky AM, Dominov JA, Miller JB. Intermediate filaments in cardiac myogenesis: nestin in the developing mouse heart. J Histochem Cytochem. 1995 Aug; 43(8):843-7. PMID: 7542682.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    14. Kachinsky AM, Dominov JA, Miller JB. Myogenesis and the intermediate filament protein, nestin. Dev Biol. 1994 Sep; 165(1):216-28. PMID: 8088440.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    15. Miller JB, Everitt EA, Smith TH, Block NE, Dominov JA. Cellular and molecular diversity in skeletal muscle development: news from in vitro and in vivo. Bioessays. 1993 Mar; 15(3):191-6. PMID: 8387785.
      Citations: 12     Fields:    Translation:AnimalsCells
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