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Jean King PhD

TitleAdjunct Professor
InstitutionUMass Chan Medical School
AddressUMass Chan Medical School
55 Lake Avenue North S7-830
Worcester MA 01655
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DivisionPsychiatry Research

    InstitutionT.H. Chan School of Medicine

    Collapse Biography 
    Collapse education and training
    Saint Francis College, Brooklyn, NY, United StatesBSBiology
    City University of New York, New York, NY, United StatesMSCell Biology
    New York University, New York, NY, United StatesPHDBiology/Neurophysiology
    Collapse awards and honors
    2017 - 2020National Center for Complementary and Integrative Health (NCCIH) , NIH
    2016Doug Ziedonis- Outstanding Career Mentor Award –Psychiatry Department, University of Massachusetts Medical School
    2012Outstanding Mentor Award – Women’s Faculty Committee , University of Massachusetts Medical School
    2011 - 2012Executive Leadership in Academic Medicine (ELAM) Fellow, International Center for Executive Leadership in Academics, Drexel University
    2009Outstanding Advocate for Girls Award , Girls Incorporated of Worcester
    2008Advocate for Adolescent Girls and Mentor to Women of All Ages, Commonwealth of Massachusetts
    2008University of Massachusetts President’s Public Service Award , University of Massachusetts Medical School
    2008Outstanding Community Service Award - Women’s Faculty Committee , University of Massachusetts Medical School
    2004Erskine Award in Science and Medicine, YWCA of Central Massachusetts
    1993Florence Siebert Memorial Scholarship, American Association of University Women
    1988Distinguished Merit Dissertation Award , New York University

    Collapse Overview 
    Collapse overview

    Dr. King's lab utilizes translational imaging paradigms to investigate several brain alterations related to emotional and cognitive processing particularly linked to stressors including addiction, ADHD and Traumatic Brain Injury in both preclinical and clinical populations. More recently she has extended the focus to include co-morbidities between addiction and mental health disorders, as well as interventions that minimize the negative impact of stress on the brain--like mindfulness.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. King JA, Nephew BC, Choudhury A, Poirier GL, Lim A, Mandrekar P. Chronic alcohol-induced liver injury correlates with memory deficits: Role for neuroinflammation. Alcohol. 2020 03; 83:75-81. PMID: 31398460.
      Citations: 11     Fields:    Translation:Animals
    2. Lee A, Gansler D, Zhang N, Jerram MW, King JA, Fulwiler C,. Relationship of mindful awareness to neural processing of angry faces and impact of mindfulness training: a pilot investigation. Psychiatry Research: Neuroimaging. 2017.
    3. Poirier GL, Huang W, Tam K, DiFranza JR, King JA. Evidence of altered brain responses to nicotine in an animal model of ADHD. Nicotine and Tobacco Research. 2017.
    4. Fulwiler C, Siegel JA, Allison J, Rosal MC, Brewer J, King JA. Keeping Weight Off: study protocol of an RCT to investigate brain changes associated with mindfulness-based stress reduction. BMJ Open. 2016 11 30; 6(11):e012573. PMID: 27903561.
      Citations: 4     Fields:    Translation:Humans
    5. Poirier GL, Huang W, Tam K, DiFranza JR, King JA. Awake whole-brain functional connectivity alterations in the adolescent spontaneously hypertensive rat feature visual streams and striatal networks. Brain Struct Funct. 2017 May; 222(4):1673-1683. PMID: 27680743.
      Citations: 5     Fields:    Translation:Animals
    6. Nephew BC, Huang W, Poirier GL, Payne L, King JA. Altered neural connectivity in adult female rats exposed to early life social stress. Behav Brain Res. 2017 01 01; 316:225-233. PMID: 27594665.
      Citations: 16     Fields:    Translation:Animals
    7. Henninger N, Bouley J, Sikoglu EM, An J, Moore CM, King JA, Bowser R, Freeman MR, Brown RH. Attenuated traumatic axonal injury and improved functional outcome after traumatic brain injury in mice lacking Sarm1. Brain. 2016 Apr; 139(Pt 4):1094-105. PMID: 26912636.
      Citations: 99     Fields:    Translation:AnimalsCells
    8. Nishi R, Castaneda E, Davis GW, Fenton AA, Hofmann HA, King J, and Trujillo KA. The Global Challenge in Neuroscience Education and Training: The MBL Perspective. Neuron. 2016; 3(92):632-636.
    9. DiFranza J, Huang W, King JA. Neuropathology of Drug Addictions and Substance Abuse and Substance Misuse Volume 1: Foundations of Understanding, Tobacco, Alcohol, Cannabinoids and Opioids. Nicotine Dependence and the Anterior Cingulate-Precuneus Pathway: Using Neuroimaging to Test Addiction Theories. 2016.
    10. Sikoglu EM, Liso Navarro AA, Czerniak SM, McCafferty J, Eisenstock J, Stevenson JH, King JA, Moore CM. Effects of Recent Concussion on Brain Bioenergetics: A Phosphorus-31 Magnetic Resonance Spectroscopy Study. Cogn Behav Neurol. 2015 Dec; 28(4):181-7. PMID: 26705264.
      Citations: 2     Fields:    Translation:Humans
    11. Czerniak SM, Sikoglu EM, Liso Navarro AA, McCafferty J, Eisenstock J, Stevenson JH, King JA, Moore CM. A resting state functional magnetic resonance imaging study of concussion in collegiate athletes. Brain Imaging Behav. 2015 Jun; 9(2):323-32. PMID: 25112544.
      Citations: 15     Fields:    Translation:Humans
    12. Li M, Deng W, He Z, Wang Q, Huang C, Jiang L, Gong Q, Ziedonis DM, King JA, Ma X, Zhang N, Li T. A splitting brain: Imbalanced neural networks in schizophrenia. Psychiatry Res. 2015 May 30; 232(2):145-53. PMID: 25819347.
      Citations: 11     Fields:    Translation:Humans
    13. Liso Navarro AA, Sikoglu EM, Heinze CR, Rogan RC, Russell VA, King JA, Moore CM. Effect of diet on brain metabolites and behavior in spontaneously hypertensive rats. Behav Brain Res. 2014 Aug 15; 270:240-7. PMID: 24855038.
      Citations: 5     Fields:    Translation:Animals
    14. Huang W, King JA, Ursprung WW, Zheng S, Zhang N, Kennedy DN, Ziedonis D, DiFranza JR. The development and expression of physical nicotine dependence corresponds to structural and functional alterations in the anterior cingulate-precuneus pathway. Brain Behav. 2014 May; 4(3):408-17. PMID: 24944870.
      Citations: 33     Fields:    Translation:Humans
    15. Sikoglu EM, Heffernan ME, Tam K, Sicard KM, Bratane BT, Quan M, Fisher M, King JA. Enhancement in cognitive function recovery by granulocyte-colony stimulating factor in a rodent model of traumatic brain injury. Behav Brain Res. 2014 Feb 01; 259:354-6. PMID: 24239694.
      Citations: 7     Fields:    Translation:Animals
    16. Huang W, DiFranza JR, Kennedy DN, Zhang N, Ziedonis D, Ursprung S, King JA. Progressive levels of physical dependence to tobacco coincide with changes in the anterior cingulum bundle microstructure. PLoS One. 2013; 8(7):e67837. PMID: 23861816.
      Citations: 16     Fields:    Translation:Humans
    17. Heffernan ME, Huang W, Sicard KM, Bratane BT, Sikoglu EM, Zhang N, Fisher M, King JA. Multi-modal approach for investigating brain and behavior changes in an animal model of traumatic brain injury. J Neurotrauma. 2013 Jun 01; 30(11):1007-12. PMID: 23294038.
      Citations: 10     Fields:    Translation:Animals
    18. Czerniak SM, Sikoglu EM, King JA, Kennedy DN, Mick E, Frazier J, Moore CM. Areas of the brain modulated by single-dose methylphenidate treatment in youth with ADHD during task-based fMRI: a systematic review. Harv Rev Psychiatry. 2013 May-Jun; 21(3):151-62. PMID: 23660970.
      Citations: 22     Fields:    Translation:Humans
    19. Fulwiler CE, King JA, Zhang N. Amygdala-orbitofrontal resting-state functional connectivity is associated with trait anger. Neuroreport. 2012 Jul 11; 23(10):606-10. PMID: 22617448.
      Citations: 38     Fields:    Translation:Humans
    20. Rane P, Shields J, Heffernan M, Guo Y, Akbarian S, King JA. The histone deacetylase inhibitor, sodium butyrate, alleviates cognitive deficits in pre-motor stage PD. Neuropharmacology. 2012; 7(62):2408-11.
    21. Huang W, Heffernan ME, Li Z, Zhang N. Fear induced neuronal alterations in a genetic model of depression: an fMRI study on awake animals. Neuroscience Letters. 2012; (489):74-78.
    22. Rane P, King JA. Exploring aversion in an animal model of pre-motor stage PD. Neuroscience. 2011; 181(5):189-95.
    23. Peters ML, Kleinman J, Huang W, Cauley KA, Ravin PD, Novak P, Bourisly A, King JA, Pilitsis JG. Assessment of Olfactory Processing in Parkinson's Disease Patients. Senior Scholars Program, University of Massachusetts Medical School. 2011.
    24. Peters ML, Ravin PD, Novak P, Burrows AM, Swearer J, King JA, Dundamadappa SK, Pilitsis JG. DBS-implanted Parkinson's Disease Patients Show Better Olfaction Than Those Treated Medically. Neurological Bulletin. 2010; (2):1-6.
    25. King JA, Rosal MC, Ma Y, Reed GW. Association of stress, hostility and plasma testosterone levels. Neuro Endocrinol Lett. 2005 Aug; 26(4):355-60. PMID: 16136009.
      Citations: 8     Fields:    Translation:Humans
    26. King JA, Garelick TS, Brevard ME, Chen W, Messenger TL, Duong TQ, Ferris CF. Procedure for minimizing stress for fMRI studies in conscious rats. J Neurosci Methods. 2005 Oct 30; 148(2):154-60. PMID: 15964078.
      Citations: 103     Fields:    Translation:Animals
    27. King JA, De Oliveira WL, Patel N. Deficits in testosterone facilitate enhanced fear response. Psychoneuroendocrinology. 2005 May; 30(4):333-40. PMID: 15694113.
      Citations: 14     Fields:    Translation:Animals
    28. King JA, Tenney J, Rossi V, Colamussi L, Burdick S. Neural substrates underlying impulsivity. Ann N Y Acad Sci. 2003 Dec; 1008:160-9. PMID: 14998882.
      Citations: 20     Fields:    Translation:Animals
    29. King JA, Mandansky D, King S, Fletcher KE, Brewer J. Early sexual abuse and low cortisol. Psychiatry Clin Neurosci. 2001 Feb; 55(1):71-4. PMID: 11235861.
      Citations: 37     Fields:    Translation:Humans
    30. King JA, Rosal MC, Ma Y, Reed G, Kelly TA, Stanek EJ, Ockene IS. Sequence and seasonal effects of salivary cortisol. Behav Med. 2000; 26(2):67-73. PMID: 11147291.
      Citations: 14     Fields:    Translation:Humans
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