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Lila Gierasch to Protein Sorting Signals

This is a "connection" page, showing publications Lila Gierasch has written about Protein Sorting Signals.
Connection Strength

2.960
  1. Cl?rico EM, Maki JL, Gierasch LM. Use of synthetic signal sequences to explore the protein export machinery. Biopolymers. 2008; 90(3):307-19.
    View in: PubMed
    Score: 0.287
  2. Chou YT, Gierasch LM. The conformation of a signal peptide bound by Escherichia coli preprotein translocase SecA. J Biol Chem. 2005 Sep 23; 280(38):32753-60.
    View in: PubMed
    Score: 0.243
  3. Triplett TL, Sgrignoli AR, Gao FB, Yang YB, Tai PC, Gierasch LM. Functional signal peptides bind a soluble N-terminal fragment of SecA and inhibit its ATPase activity. J Biol Chem. 2001 Jun 01; 276(22):19648-55.
    View in: PubMed
    Score: 0.179
  4. Swain JF, Gierasch LM. Signal peptides bind and aggregate RNA. An alternative explanation for GTPase inhibition in the signal recognition particle. J Biol Chem. 2001 Apr 13; 276(15):12222-7.
    View in: PubMed
    Score: 0.177
  5. Zheng N, Gierasch LM. Signal sequences: the same yet different. Cell. 1996 Sep 20; 86(6):849-52.
    View in: PubMed
    Score: 0.131
  6. Jones JD, Gierasch LM. Effect of charged residue substitutions on the membrane-interactive properties of signal sequences of the Escherichia coli LamB protein. Biophys J. 1994 Oct; 67(4):1534-45.
    View in: PubMed
    Score: 0.115
  7. Jones JD, Gierasch LM. Effect of charged residue substitutions on the thermodynamics of signal peptide-lipid interactions for the Escherichia coli LamB signal sequence. Biophys J. 1994 Oct; 67(4):1546-61.
    View in: PubMed
    Score: 0.115
  8. Wang Z, Jones JD, Rizo J, Gierasch LM. Membrane-bound conformation of a signal peptide: a transferred nuclear Overhauser effect analysis. Biochemistry. 1993 Dec 21; 32(50):13991-9.
    View in: PubMed
    Score: 0.109
  9. Rizo J, Blanco FJ, Kobe B, Bruch MD, Gierasch LM. Conformational behavior of Escherichia coli OmpA signal peptides in membrane mimetic environments. Biochemistry. 1993 May 11; 32(18):4881-94.
    View in: PubMed
    Score: 0.104
  10. Maki JL, Krishnan B, Gierasch LM. Using a low denaturant model to explore the conformational features of translocation-active SecA. Biochemistry. 2012 Feb 21; 51(7):1369-79.
    View in: PubMed
    Score: 0.095
  11. Gierasch LM, Jones JD, Landry SJ, Stradley SJ. Biophysical studies of recognition sequences for targeting and folding. Antonie Van Leeuwenhoek. 1992 Feb; 61(2):93-9.
    View in: PubMed
    Score: 0.095
  12. Hoyt DW, Gierasch LM. Hydrophobic content and lipid interactions of wild-type and mutant OmpA signal peptides correlate with their in vivo function. Biochemistry. 1991 Oct 22; 30(42):10155-63.
    View in: PubMed
    Score: 0.093
  13. Hoyt DW, Gierasch LM. A peptide corresponding to an export-defective mutant OmpA signal sequence with asparagine in the hydrophobic core is unable to insert into model membranes. J Biol Chem. 1991 Aug 05; 266(22):14406-12.
    View in: PubMed
    Score: 0.092
  14. McKnight CJ, Stradley SJ, Jones JD, Gierasch LM. Conformational and membrane-binding properties of a signal sequence are largely unaltered by its adjacent mature region. Proc Natl Acad Sci U S A. 1991 Jul 01; 88(13):5799-803.
    View in: PubMed
    Score: 0.091
  15. McKnight CJ, Rafalski M, Gierasch LM. Fluorescence analysis of tryptophan-containing variants of the LamB signal sequence upon insertion into a lipid bilayer. Biochemistry. 1991 Jun 25; 30(25):6241-6.
    View in: PubMed
    Score: 0.091
  16. Jones JD, McKnight CJ, Gierasch LM. Biophysical studies of signal peptides: implications for signal sequence functions and the involvement of lipid in protein export. J Bioenerg Biomembr. 1990 Jun; 22(3):213-32.
    View in: PubMed
    Score: 0.085
  17. Bruch MD, Gierasch LM. Comparison of helix stability in wild-type and mutant LamB signal sequences. J Biol Chem. 1990 Mar 05; 265(7):3851-8.
    View in: PubMed
    Score: 0.083
  18. Bruch MD, McKnight CJ, Gierasch LM. Helix formation and stability in a signal sequence. Biochemistry. 1989 Oct 17; 28(21):8554-61.
    View in: PubMed
    Score: 0.081
  19. McKnight CJ, Briggs MS, Gierasch LM. Functional and nonfunctional LamB signal sequences can be distinguished by their biophysical properties. J Biol Chem. 1989 Oct 15; 264(29):17293-7.
    View in: PubMed
    Score: 0.081
  20. Cornell DG, Dluhy RA, Briggs MS, McKnight CJ, Gierasch LM. Conformations and orientations of a signal peptide interacting with phospholipid monolayers. Biochemistry. 1989 Apr 04; 28(7):2789-97.
    View in: PubMed
    Score: 0.078
  21. Gierasch LM. Signal sequences. Biochemistry. 1989 Feb 07; 28(3):923-30.
    View in: PubMed
    Score: 0.077
  22. Cl?rico EM, Szymanska A, Gierasch LM. Exploring the interactions between signal sequences and E. coli SRP by two distinct and complementary crosslinking methods. Biopolymers. 2009; 92(3):201-11.
    View in: PubMed
    Score: 0.077
  23. Chen L, Tai PC, Briggs MS, Gierasch LM. Protein translocation into Escherichia coli membrane vesicles is inhibited by functional synthetic signal peptides. J Biol Chem. 1987 Feb 05; 262(4):1427-9.
    View in: PubMed
    Score: 0.067
  24. Briggs MS, Cornell DG, Dluhy RA, Gierasch LM. Conformations of signal peptides induced by lipids suggest initial steps in protein export. Science. 1986 Jul 11; 233(4760):206-8.
    View in: PubMed
    Score: 0.065
  25. Briggs MS, Gierasch LM. Molecular mechanisms of protein secretion: the role of the signal sequence. Adv Protein Chem. 1986; 38:109-80.
    View in: PubMed
    Score: 0.062
  26. Benach J, Chou YT, Fak JJ, Itkin A, Nicolae DD, Smith PC, Wittrock G, Floyd DL, Golsaz CM, Gierasch LM, Hunt JF. Phospholipid-induced monomerization and signal-peptide-induced oligomerization of SecA. J Biol Chem. 2003 Feb 07; 278(6):3628-38.
    View in: PubMed
    Score: 0.050
  27. Cleverley RM, Gierasch LM. Mapping the signal sequence-binding site on SRP reveals a significant role for the NG domain. J Biol Chem. 2002 Nov 29; 277(48):46763-8.
    View in: PubMed
    Score: 0.050
  28. Sankaram MB, Marsh D, Gierasch LM, Thompson TE. Reorganization of lipid domain structure in membranes by a transmembrane peptide: an ESR spin label study on the effect of the Escherichia coli outer membrane protein A signal peptide on the fluid lipid domain connectivity in binary mixtures of dimyristoyl phosphatidylcholine and distearoyl phosphatidylcholine. Biophys J. 1994 Jun; 66(6):1959-68.
    View in: PubMed
    Score: 0.028
  29. Lin BR, Gierasch LM, Jiang C, Tai PC. Electrophysiological studies in Xenopus oocytes for the opening of Escherichia coli SecA-dependent protein-conducting channels. J Membr Biol. 2006; 214(2):103-13.
    View in: PubMed
    Score: 0.017
  30. Gierasch LM, Rockwell AL, Thompson KF, Briggs MS. Conformation-function relationships in hydrophobic peptides: interior turns and signal sequences. Biopolymers. 1985 Jan; 24(1):117-35.
    View in: PubMed
    Score: 0.015
  31. Briggs MS, Gierasch LM. Exploring the conformational roles of signal sequences: synthesis and conformational analysis of lambda receptor protein wild-type and mutant signal peptides. Biochemistry. 1984 Jul 03; 23(14):3111-4.
    View in: PubMed
    Score: 0.014
  32. Hoyt DW, Cyr DM, Gierasch LM, Douglas MG. Interaction of peptides corresponding to mitochondrial presequences with membranes. J Biol Chem. 1991 Nov 15; 266(32):21693-9.
    View in: PubMed
    Score: 0.006
  33. Briggs MS, Gierasch LM, Zlotnick A, Lear JD, DeGrado WF. In vivo function and membrane binding properties are correlated for Escherichia coli lamB signal peptides. Science. 1985 May 31; 228(4703):1096-9.
    View in: PubMed
    Score: 0.004
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