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Greg Tew Ph.D.

TitleProfessor
InstitutionUniversity of Massachusetts Amherst
DepartmentCollege of Natural Sciences
AddressConte Polymer Research Center
Amherst, MA 01003
Phone413-577-1612
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mohan D, Sherman HL, Mitra A, Lawlor R, Shanthalingam S, Ullom J, Pobezinskaya EL, Zhang G, Osborne BA, Pobezinsky LA, Tew GN, Minter LM. LKB1 isoform expression modulates T cell plasticity downstream of PKC? and IL-6. Mol Immunol. 2023 05; 157:129-141. PMID: 37018939.
      Citations:    Fields:    Translation:Cells
    2. Clarke BR, Kim H, Ilton M, Watkins JJ, Crosby AJ, Tew GN. The Impact of Polymerization Chemistry on the Mechanical Properties of Poly(dimethylsiloxane) Bottlebrush Elastomers. Macromolecules. 2022 Dec 13; 55(23):10312-10319. PMID: 37502106.
      Citations:    Fields:    
    3. Koch KC, Tew GN. Functional antibody delivery: Advances in cellular manipulation. Adv Drug Deliv Rev. 2023 01; 192:114586. PMID: 36280179.
      Citations:    Fields:    Translation:HumansCells
    4. Sacligil I, Barney CW, Crosby AJ, Tew GN. Bond strength regime dictates stress relaxation behavior. Soft Matter. 2022 Jul 06; 18(26):4937-4943. PMID: 35730637.
      Citations: 1     Fields:    
    5. Barney CW, Sacligil I, Tew GN, Crosby AJ. Linking cavitation and fracture to molecular scale structural damage of model networks. Soft Matter. 2022 Jun 08; 18(22):4220-4226. PMID: 35607851.
      Citations:    Fields:    
    6. Clarke BR, Tew GN. Bottlebrush Amphiphilic Polymer Co-Networks. Macromolecules. 2022 Jun 28; 55(12):5131-5139. PMID: 37485288.
      Citations: 1     Fields:    
    7. Davis HC, Pan X, Kirsch ZJ, Vachet RW, Tew GN. Covalent Labeling-Mass Spectrometry Provides a Molecular Understanding of Noncovalent Polymer-Protein Complexation. ACS Biomater Sci Eng. 2022 06 13; 8(6):2489-2499. PMID: 35608244.
      Citations:    Fields:    Translation:Cells
    8. Barney CW, Ye Z, Sacligil I, McLeod KR, Zhang H, Tew GN, Riggleman RA, Crosby AJ. Fracture of model end-linked networks. Proc Natl Acad Sci U S A. 2022 02 15; 119(7). PMID: 35145027.
      Citations: 2     Fields:    
    9. Clarke BR, Tew GN. Synthesis and characterization of poly(ethylene glycol) bottlebrush networks via ring-opening metathesis polymerization. J Polym Sci (2020). 2022 May 01; 60(9):1501-1510. PMID: 35967758.
      Citations:    
    10. Davis HC, Posey ND, Tew GN. Protein Binding and Release by Polymeric Cell-Penetrating Peptide Mimics. Biomacromolecules. 2022 01 10; 23(1):57-66. PMID: 34879198.
      Citations: 2     Fields:    Translation:Cells
    11. Hango CR, Backlund CM, Davis HC, Posey ND, Minter LM, Tew GN. Non-Covalent Carrier Hydrophobicity as a Universal Predictor of Intracellular Protein Activity. Biomacromolecules. 2021 07 12; 22(7):2850-2863. PMID: 34156837.
      Citations: 5     Fields:    
    12. Tiwari S, Kazemi-Moridani A, Zheng Y, Barney CW, McLeod KR, Dougan CE, Crosby AJ, Tew GN, Peyton SR, Cai S, Lee JH. Seeded laser-induced cavitation for studying high-strain-rate irreversible deformation of soft materials. Soft Matter. 2020 Aug 20. PMID: 33021618.
      Citations: 4     Fields:    
    13. Ozay EI, Shanthalingam S, Torres JA, Osborne BA, Tew GN, Minter LM. Protein Kinase C Theta Modulates PCMT1 through hnRNPL to Regulate FOXP3 Stability in Regulatory T Cells. Mol Ther. 2020 10 07; 28(10):2220-2236. PMID: 32592691.
      Citations: 3     Fields:    Translation:Cells
    14. Ozay EI, Shanthalingam S, Sherman HL, Torres JA, Osborne BA, Tew GN, Minter LM. Cell-Penetrating Anti-Protein Kinase C Theta Antibodies Act Intracellularly to Generate Stable, Highly Suppressive Regulatory T Cells. Mol Ther. 2020 09 02; 28(9):1987-2006. PMID: 32492367.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    15. Barney CW, Dougan CE, McLeod KR, Kazemi-Moridani A, Zheng Y, Ye Z, Tiwari S, Sacligil I, Riggleman RA, Cai S, Lee JH, Peyton SR, Tew GN, Crosby AJ. Cavitation in soft matter. Proc Natl Acad Sci U S A. 2020 04 28; 117(17):9157-9165. PMID: 32291337.
      Citations: 19     Fields:    
    16. Backlund CM, Hango CR, Minter LM, Tew GN. Protein and Antibody Delivery into Difficult-to-Transfect Cells by Polymeric Peptide Mimics. ACS Appl Bio Mater. 2020 Jan 21; 3(1):180-185. PMID: 35019434.
      Citations: 2     Fields:    
    17. Backlund CM, Parhamifar L, Minter L, Tew GN, Andresen TL. Protein Transduction Domain Mimics Facilitate Rapid Antigen Delivery into Monocytes. Mol Pharm. 2019 06 03; 16(6):2462-2469. PMID: 31095395.
      Citations:    Fields:    Translation:HumansCells
    18. Geiger S, Ozay EI, Geumann U, Hereth MK, Magnusson T, Shanthalingam S, Hirsch D, K?lin S, G?nther C, Osborne BA, Tew GN, Hermann FG, Minter LM. Alpha-1 Antitrypsin-Expressing Mesenchymal Stromal Cells Confer a Long-Term Survival Benefit in a Mouse Model of Lethal GvHD. Mol Ther. 2019 08 07; 27(8):1436-1451. PMID: 31138510.
      Citations: 2     Fields:    Translation:AnimalsCells
    19. Ozay EI, Vijayaraghavan J, Gonzalez-Perez G, Shanthalingam S, Sherman HL, Garrigan DT, Chandiran K, Torres JA, Osborne BA, Tew GN, Slukvin II, Macdonald RA, Kelly K, Minter LM. Cymerus? iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease. Stem Cell Res. 2019 03; 35:101401. PMID: 30738321.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    20. Posey ND, Tew GN. Associative and Dissociative Processes in Non-Covalent Polymer-Mediated Intracellular Protein Delivery. Chem Asian J. 2018 Nov 16; 13(22):3351-3365. PMID: 30152199.
      Citations: 3     Fields:    Translation:HumansCells
    21. Sgolastra F, Kuksin CA, Gonzalez-Perez G, Minter LM, Tew GN. Enhanced TAT-Cre Protein Transduction for Efficient Gene Recombination in T cells. ACS Appl Bio Mater. 2018 Aug 20; 1(2):444-451. PMID: 35016365.
      Citations: 1     Fields:    
    22. Posey ND, Hango CR, Minter LM, Tew GN. The Role of Cargo Binding Strength in Polymer-Mediated Intracellular Protein Delivery. Bioconjug Chem. 2018 08 15; 29(8):2679-2690. PMID: 30080401.
      Citations: 6     Fields:    Translation:HumansCells
    23. Kwasny MT, Zhu L, Hickner MA, Tew GN. Thermodynamics of Counterion Release Is Critical for Anion Exchange Membrane Conductivity. J Am Chem Soc. 2018 06 27; 140(25):7961-7969. PMID: 29901997.
      Citations: 14     Fields:    
    24. Ozay EI, Sherman HL, Mello V, Trombley G, Lerman A, Tew GN, Yadava N, Minter LM. Rotenone Treatment Reveals a Role for Electron Transport Complex I in the Subcellular Localization of Key Transcriptional Regulators During T Helper Cell Differentiation. Front Immunol. 2018; 9:1284. PMID: 29930555.
      Citations: 3     Fields:    Translation:AnimalsCells
    25. Sarapas JM, Backlund CM, deRonde BM, Minter LM, Tew GN. ROMP- and RAFT-Based Guanidinium-Containing Polymers as Scaffolds for Protein Mimic Synthesis. Chemistry. 2017 May 17; 23(28):6858-6863. PMID: 28370636.
      Citations: 4     Fields:    Translation:HumansCells
    26. Sgolastra F, Backlund CM, Ilker Ozay E, deRonde BM, Minter LM, Tew GN. Sequence segregation improves non-covalent protein delivery. J Control Release. 2017 05 28; 254:131-136. PMID: 28363520.
      Citations: 11     Fields:    Translation:HumansCells
    27. Tezgel A?, Jacobs P, Backlund CM, Telfer JC, Tew GN. Synthetic Protein Mimics for Functional Protein Delivery. Biomacromolecules. 2017 03 13; 18(3):819-825. PMID: 28165726.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    28. Scott RW, Tew GN. Mimics of Host Defense Proteins; Strategies for Translation to Therapeutic Applications. Curr Top Med Chem. 2017; 17(5):576-589. PMID: 27411325.
      Citations: 26     Fields:    Translation:HumansCells
    29. Sarapas JM, Tew GN. Thiol-Ene Step-Growth as a Versatile Route to Functional Polymers. Angew Chem Int Ed Engl. 2016 12 19; 55(51):15860-15863. PMID: 27873435.
      Citations: 5     Fields:    
    30. Backlund CM, Sgolastra F, Otter R, Minter L, Takeuchi T, Futaki S, Tew GN. Increased Hydrophobic Block Length of PTDMs Promotes Protein Internalization. Polym Chem. 2016 Dec 28; 7(48):7514-7521. PMID: 29093759.
      Citations:    
    31. Caffrey LM, deRonde BM, Minter LM, Tew GN. Mapping Optimal Charge Density and Length of ROMP-Based PTDMs for siRNA Internalization. Biomacromolecules. 2016 10 10; 17(10):3205-3212. PMID: 27599388.
      Citations: 6     Fields:    Translation:HumansCells
    32. Ozay EI, Gonzalez-Perez G, Torres JA, Vijayaraghavan J, Lawlor R, Sherman HL, Garrigan DT, Burnside AS, Osborne BA, Tew GN, Minter LM. Intracellular Delivery of Anti-pPKC? (Thr538) via Protein Transduction Domain Mimics for Immunomodulation. Mol Ther. 2016 Dec; 24(12):2118-2130. PMID: 27633441.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    33. Lis M, Dorner F, Tew GN, Lienkamp K. Anionic Lipid Content Presents a Barrier to the Activity of ROMP-Based Synthetic Mimics of Protein Transduction Domains (PTDMs). Langmuir. 2016 06 14; 32(23):5946-54. PMID: 27182683.
      Citations: 1     Fields:    Translation:HumansCells
    34. deRonde BM, Posey ND, Otter R, Caffrey LM, Minter LM, Tew GN. Optimal Hydrophobicity in Ring-Opening Metathesis Polymerization-Based Protein Mimics Required for siRNA Internalization. Biomacromolecules. 2016 06 13; 17(6):1969-77. PMID: 27103189.
      Citations: 9     Fields:    Translation:HumansCells
    35. Backlund CM, Takeuchi T, Futaki S, Tew GN. Relating structure and internalization for ROMP-based protein mimics. Biochim Biophys Acta. 2016 Jul; 1858(7 Pt A):1443-50. PMID: 27039278.
      Citations: 4     Fields:    Translation:HumansCells
    36. deRonde BM, Torres JA, Minter LM, Tew GN. Development of Guanidinium-Rich Protein Mimics for Efficient siRNA Delivery into Human T Cells. Biomacromolecules. 2015 Oct 12; 16(10):3172-9. PMID: 26324222.
      Citations: 10     Fields:    Translation:HumansCells
    37. Lein M, deRonde BM, Sgolastra F, Tew GN, Holden MA. Protein transport across membranes: Comparison between lysine and guanidinium-rich carriers. Biochim Biophys Acta. 2015 Nov; 1848(11 Pt A):2980-4. PMID: 26342679.
      Citations: 4     Fields:    Translation:Cells
    38. deRonde BM, Tew GN. Development of protein mimics for intracellular delivery. Biopolymers. 2015 Jul; 104(4):265-80. PMID: 25858701.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    39. deRonde BM, Birke A, Tew GN. Design of aromatic-containing cell-penetrating peptide mimics with structurally modified p electronics. Chemistry. 2015 Feb 09; 21(7):3013-9. PMID: 25537501.
      Citations: 9     Fields:    
    40. Walker CN, Bryson KC, Hayward RC, Tew GN. Wide bicontinuous compositional windows from co-networks made with telechelic macromonomers. ACS Nano. 2014 Dec 23; 8(12):12376-85. PMID: 25415537.
      Citations: 4     Fields:    
    41. Walker CN, Sarapas JM, Kung V, Hall AL, Tew GN. Multiblock Copolymers by Thiol Addition Across Norbornene. ACS Macro Lett. 2014 May 20; 3(5):453-457. PMID: 35590781.
      Citations: 1     Fields:    
    42. Saffer EM, Lackey MA, Griffin DM, Kishore S, Tew GN, Bhatia SR. SANS study of highly resilient poly(ethylene glycol) hydrogels. Soft Matter. 2014 Mar 28; 10(12):1905-16. PMID: 24652367.
      Citations: 17     Fields:    Translation:Cells
    43. Sgolastra F, Minter LM, Osborne BA, Tew GN. Importance of sequence specific hydrophobicity in synthetic protein transduction domain mimics. Biomacromolecules. 2014 Mar 10; 15(3):812-20. PMID: 24506414.
      Citations: 13     Fields:    Translation:HumansCells
    44. Leng C, Gibney KA, Liu Y, Tew GN, Chen Z. In Situ Probing the Surface Restructuring of Antibiofouling Amphiphilic Polybetaines in Water. ACS Macro Lett. 2013 Nov 19; 2(11):1011-1015. PMID: 35581870.
      Citations: 2     Fields:    
    45. Sgolastra F, Deronde BM, Sarapas JM, Som A, Tew GN. Designing mimics of membrane active proteins. Acc Chem Res. 2013 Dec 17; 46(12):2977-87. PMID: 24007507.
      Citations: 29     Fields:    Translation:Cells
    46. Zhang K, Zha Y, Peng B, Chen Y, Tew GN. Metallo-supramolecular cyclic polymers. J Am Chem Soc. 2013 Oct 30; 135(43):15994-7. PMID: 23930776.
      Citations: 6     Fields:    
    47. Fu TH, Li Y, Thaker HD, Scott RW, Tew GN. Expedient Synthesis of SMAMPs via Click Chemistry. ACS Med Chem Lett. 2013 Sep 12; 4(9):841-5. PMID: 24936243.
      Citations:    
    48. Martin DT, Hoimes CJ, Kaimakliotis HZ, Cheng CJ, Zhang K, Liu J, Wheeler MA, Kelly WK, Tew GN, Saltzman WM, Weiss RM. Nanoparticles for urothelium penetration and delivery of the histone deacetylase inhibitor belinostat for treatment of bladder cancer. Nanomedicine. 2013 Nov; 9(8):1124-34. PMID: 23764660.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    49. Thaker HD, Cankaya A, Scott RW, Tew GN. Role of Amphiphilicity in the Design of Synthetic Mimics of Antimicrobial Peptides with Gram-negative Activity. ACS Med Chem Lett. 2013 May 09; 4(5):481-485. PMID: 23814644.
      Citations:    
    50. Schmidt NW, Lis M, Zhao K, Lai GH, Alexandrova AN, Tew GN, Wong GC. Molecular basis for nanoscopic membrane curvature generation from quantum mechanical models and synthetic transporter sequences. J Am Chem Soc. 2012 Nov 21; 134(46):19207-16. PMID: 23061419.
      Citations: 30     Fields:    
    51. Tezgel A?, Gonzalez-Perez G, Telfer JC, Osborne BA, Minter LM, Tew GN. Novel protein transduction domain mimics as nonviral delivery vectors for siRNA targeting NOTCH1 in primary human T cells. Mol Ther. 2013 Jan; 21(1):201-9. PMID: 23070119.
      Citations: 23     Fields:    Translation:HumansCells
    52. Som A, Navasa N, Percher A, Scott RW, Tew GN, Anguita J. Identification of synthetic host defense peptide mimics that exert dual antimicrobial and anti-inflammatory activities. Clin Vaccine Immunol. 2012 Nov; 19(11):1784-91. PMID: 22956655.
      Citations: 14     Fields:    Translation:AnimalsCells
    53. Zha Y, Thaker HD, Maddikeri RR, Gido SP, Tuominen MT, Tew GN. Nanostructured block-random copolymers with tunable magnetic properties. J Am Chem Soc. 2012 Sep 05; 134(35):14534-41. PMID: 22871027.
      Citations: 6     Fields:    
    54. Li Y, Kumar KN, Dabkowski JM, Corrigan M, Scott RW, N?sslein K, Tew GN. New bactericidal surgical suture coating. Langmuir. 2012 Aug 21; 28(33):12134-9. PMID: 22877364.
      Citations: 9     Fields:    Translation:Cells
    55. Thaker HD, Som A, Ayaz F, Lui D, Pan W, Scott RW, Anguita J, Tew GN. Synthetic mimics of antimicrobial peptides with immunomodulatory responses. J Am Chem Soc. 2012 Jul 11; 134(27):11088-91. PMID: 22697149.
      Citations: 31     Fields:    Translation:AnimalsCells
    56. Walker CN, Versek C, Touminen M, Tew GN. Tunable Networks from Thiolene Chemistry for Lithium Ion Conduction. ACS Macro Lett. 2012 Jun 19; 1(6):737-741. PMID: 35607095.
      Citations: 1     Fields:    
    57. Colak S, Tew GN. Amphiphilic polybetaines: the effect of side-chain hydrophobicity on protein adsorption. Biomacromolecules. 2012 May 14; 13(5):1233-9. PMID: 22515145.
      Citations: 4     Fields:    Translation:Cells
    58. Zhang K, Tew GN. Cyclic Brush Polymers by Combining Ring-Expansion Metathesis Polymerization and the "Grafting from" Technique. ACS Macro Lett. 2012 May 15; 1(5):574-579. PMID: 35607064.
      Citations:    Fields:    
    59. Zha Y, Disabb-Miller ML, Johnson ZD, Hickner MA, Tew GN. Metal-cation-based anion exchange membranes. J Am Chem Soc. 2012 Mar 14; 134(10):4493-6. PMID: 22385221.
      Citations: 23     Fields:    
    60. Cui J, Lackey MA, Madkour AE, Saffer EM, Griffin DM, Bhatia SR, Crosby AJ, Tew GN. Synthetically simple, highly resilient hydrogels. Biomacromolecules. 2012 Mar 12; 13(3):584-8. PMID: 22372639.
      Citations: 18     Fields:    
    61. Colak S, Tew GN. Dual-functional ROMP-based betaines: effect of hydrophilicity and backbone structure on nonfouling properties. Langmuir. 2012 Jan 10; 28(1):666-75. PMID: 22126398.
      Citations: 6     Fields:    Translation:Cells
    62. Som A, Reuter A, Tew GN. Protein transduction domain mimics: the role of aromatic functionality. Angew Chem Int Ed Engl. 2012 Jan 23; 51(4):980-3. PMID: 22170788.
      Citations: 30     Fields:    
    63. Som A, Xu Y, Scott RW, Tew GN. Anion mediated activation of guanidine rich small molecules. Org Biomol Chem. 2012 Jan 07; 10(1):40-2. PMID: 22025013.
      Citations: 1     Fields:    
    64. Al-Badri ZM, Maddikeri RR, Zha Y, Thaker HD, Dobriyal P, Shunmugam R, Russell TP, Tew GN. Room temperature magnetic materials from nanostructured diblock copolymers. Nat Commun. 2011 Sep 27; 2:482. PMID: 21952216.
      Citations: 8     Fields:    
    65. Maddikeri RR, Colak S, Gido SP, Tew GN. Zwitterionic polymersomes in an ionic liquid: room temperature TEM characterization. Biomacromolecules. 2011 Oct 10; 12(10):3412-7. PMID: 21902263.
      Citations: 3     Fields:    
    66. Tezgel A?, Telfer JC, Tew GN. De novo designed protein transduction domain mimics from simple synthetic polymers. Biomacromolecules. 2011 Aug 08; 12(8):3078-83. PMID: 21714570.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    67. Hu W, Som A, Tew GN. Interaction between lipids and antimicrobial oligomers studied by solid-state NMR. J Phys Chem B. 2011 Jul 07; 115(26):8474-80. PMID: 21612287.
      Citations: 1     Fields:    Translation:Cells
    68. Som A, Tezgel AO, Gabriel GJ, Tew GN. Self-activation in de novo designed mimics of cell-penetrating peptides. Angew Chem Int Ed Engl. 2011 Jun 27; 50(27):6147-50. PMID: 21591041.
      Citations: 19     Fields:    
    69. Zhang K, Lackey MA, Wu Y, Tew GN. Universal cyclic polymer templates. J Am Chem Soc. 2011 May 11; 133(18):6906-9. PMID: 21506529.
      Citations: 10     Fields:    
    70. Thaker HD, Sgolastra F, Clements D, Scott RW, Tew GN. Synthetic mimics of antimicrobial peptides from triaryl scaffolds. J Med Chem. 2011 Apr 14; 54(7):2241-54. PMID: 21388190.
      Citations: 18     Fields:    Translation:HumansCells
    71. Zhang K, Lackey MA, Cui J, Tew GN. Gels based on cyclic polymers. J Am Chem Soc. 2011 Mar 23; 133(11):4140-8. PMID: 21351775.
      Citations: 10     Fields:    
    72. Saffer EM, Tew GN, Bhatia SR. Poly(lactic acid)-poly(ethylene oxide) block copolymers: new directions in self-assembly and biomedical applications. Curr Med Chem. 2011; 18(36):5676-86. PMID: 22172072.
      Citations: 5     Fields:    Translation:Humans
    73. Agrawal SK, Sanabria-DeLong N, Bhatia SK, Tew GN, Bhatia SR. Energetics of association in poly(lactic acid)-based hydrogels with crystalline and nanoparticle-polymer junctions. Langmuir. 2010 Nov 16; 26(22):17330-8. PMID: 20945859.
      Citations:    Fields:    Translation:Cells
    74. Madkour AE, Koch AH, Lienkamp K, Tew GN. End-functionalized ROMP polymers for Biomedical Applications. Macromolecules. 2010 May 25; 43(10):4557-4561. PMID: 21499549.
      Citations: 11     Fields:    
    75. Shunmugam R, Gabriel GJ, Aamer KA, Tew GN. Metal-ligand-containing polymers: terpyridine as the supramolecular unit. Macromol Rapid Commun. 2010 May 12; 31(9-10):784-93. PMID: 21590971.
      Citations: 11     Fields:    
    76. Tew GN, Scott RW, Klein ML, Degrado WF. De novo design of antimicrobial polymers, foldamers, and small molecules: from discovery to practical applications. Acc Chem Res. 2010 Jan 19; 43(1):30-9. PMID: 19813703.
      Citations: 109     Fields:    Translation:Cells
    77. Lamboy JA, Arter JA, Knopp KA, Der D, Overstreet CM, Palermo EF, Urakami H, Yu TB, Tezgel O, Tew GN, Guan Z, Kuroda K, Weiss GA. Phage wrapping with cationic polymers eliminates nonspecific binding between M13 phage and high pI target proteins. J Am Chem Soc. 2009 Nov 18; 131(45):16454-60. PMID: 19856910.
      Citations: 14     Fields:    Translation:Cells
    78. Lienkamp K, Tew GN. Synthetic mimics of antimicrobial peptides--a versatile ring-opening metathesis polymerization based platform for the synthesis of selective antibacterial and cell-penetrating polymers. Chemistry. 2009 Nov 09; 15(44):11784-800. PMID: 19798714.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    79. Lienkamp K, Madkour AE, Kumar KN, N?sslein K, Tew GN. Antimicrobial polymers prepared by ring-opening metathesis polymerization: manipulating antimicrobial properties by organic counterion and charge density variation. Chemistry. 2009 Nov 02; 15(43):11715-22. PMID: 19798715.
      Citations: 17     Fields:    
    80. Lienkamp K, Kumar KN, Som A, N?sslein K, Tew GN. "Doubly selective" antimicrobial polymers: how do they differentiate between bacteria? Chemistry. 2009 Nov 02; 15(43):11710-4. PMID: 19790208.
      Citations: 27     Fields:    Translation:Cells
    81. Som A, Yang L, Wong GC, Tew GN. Divalent metal ion triggered activity of a synthetic antimicrobial in cardiolipin membranes. J Am Chem Soc. 2009 Oct 28; 131(42):15102-3. PMID: 19807082.
      Citations: 15     Fields:    
    82. Avery CW, Som A, Xu Y, Tew GN, Chen Z. Dependence of antimicrobial selectivity and potency on oligomer structure investigated using substrate supported lipid bilayers and sum frequency generation vibrational spectroscopy. Anal Chem. 2009 Oct 15; 81(20):8365-72. PMID: 19754103.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    83. Chen J, Hessler JA, Putchakayala K, Panama BK, Khan DP, Hong S, Mullen DG, Dimaggio SC, Som A, Tew GN, Lopatin AN, Baker JR, Holl MM, Orr BG. Cationic nanoparticles induce nanoscale disruption in living cell plasma membranes. J Phys Chem B. 2009 Aug 13; 113(32):11179-85. PMID: 19606833.
      Citations: 61     Fields:    Translation:HumansCells
    84. Colak S, Nelson CF, N?sslein K, Tew GN. Hydrophilic modifications of an amphiphilic polynorbornene and the effects on its hemolytic and antibacterial activity. Biomacromolecules. 2009 Feb 09; 10(2):353-9. PMID: 19138065.
      Citations: 16     Fields:    Translation:Cells
    85. Madkour AE, Dabkowski JM, Nusslein K, Tew GN. Fast disinfecting antimicrobial surfaces. Langmuir. 2009 Jan 20; 25(2):1060-7. PMID: 19177651.
      Citations: 18     Fields:    Translation:Cells
    86. Gabriel GJ, Maegerlein JA, Nelson CF, Dabkowski JM, Eren T, N?sslein K, Tew GN. Comparison of facially amphiphilic versus segregated monomers in the design of antibacterial copolymers. Chemistry. 2009; 15(2):433-9. PMID: 19021176.
      Citations: 23     Fields:    Translation:Cells
    87. Yang L, Gordon VD, Trinkle DR, Schmidt NW, Davis MA, DeVries C, Som A, Cronan JE, Tew GN, Wong GC. Mechanism of a prototypical synthetic membrane-active antimicrobial: Efficient hole-punching via interaction with negative intrinsic curvature lipids. Proc Natl Acad Sci U S A. 2008 Dec 30; 105(52):20595-600. PMID: 19106303.
      Citations: 45     Fields:    Translation:Cells
    88. Scott RW, DeGrado WF, Tew GN. De novo designed synthetic mimics of antimicrobial peptides. Curr Opin Biotechnol. 2008 Dec; 19(6):620-7. PMID: 18996193.
      Citations: 50     Fields:    Translation:AnimalsCells
    89. Agrawal SK, Sanabria-Delong N, Tew GN, Bhatia SR. Nanoparticle-reinforced associative network hydrogels. Langmuir. 2008 Nov 18; 24(22):13148-54. PMID: 18947244.
      Citations: 6     Fields:    Translation:Cells
    90. Gabriel GJ, Madkour AE, Dabkowski JM, Nelson CF, N?sslein K, Tew GN. Synthetic mimic of antimicrobial peptide with nonmembrane-disrupting antibacterial properties. Biomacromolecules. 2008 Nov; 9(11):2980-3. PMID: 18850741.
      Citations: 46     Fields:    Translation:HumansCells
    91. Gabriel GJ, Pool JG, Som A, Dabkowski JM, Coughlin EB, Muthukumar M, Tew GN. Interactions between antimicrobial polynorbornenes and phospholipid vesicles monitored by light scattering and microcalorimetry. Langmuir. 2008 Nov 04; 24(21):12489-95. PMID: 18841926.
      Citations: 10     Fields:    
    92. Sanabria-DeLong N, Crosby AJ, Tew GN. Photo-cross-linked PLA-PEO-PLA hydrogels from self-assembled physical networks: mechanical properties and influence of assumed constitutive relationships. Biomacromolecules. 2008 Oct; 9(10):2784-91. PMID: 18817440.
      Citations: 7     Fields:    Translation:CellsPHPublic Health
    93. Al-Badri ZM, Som A, Lyon S, Nelson CF, N?sslein K, Tew GN. Investigating the effect of increasing charge density on the hemolytic activity of synthetic antimicrobial polymers. Biomacromolecules. 2008 Oct; 9(10):2805-10. PMID: 18816096.
      Citations: 18     Fields:    Translation:HumansCells
    94. Jiang J, Tew GN. Synthesis of macrocycle isomers via metathesis cyclization and their self-assembly from aqueous solutions. Org Lett. 2008 Oct 16; 10(20):4393-6. PMID: 18808129.
      Citations:    Fields:    
    95. Hennig A, Gabriel GJ, Tew GN, Matile S. Stimuli-responsive polyguanidino-oxanorbornene membrane transporters as multicomponent sensors in complex matrices. J Am Chem Soc. 2008 Aug 06; 130(31):10338-44. PMID: 18624407.
      Citations: 27     Fields:    
    96. Lienkamp K, Madkour AE, Musante A, Nelson CF, N?sslein K, Tew GN. Antimicrobial polymers prepared by ROMP with unprecedented selectivity: a molecular construction kit approach. J Am Chem Soc. 2008 Jul 30; 130(30):9836-43. PMID: 18593128.
      Citations: 86     Fields:    Translation:HumansCells
    97. Som A, Tew GN. Influence of lipid composition on membrane activity of antimicrobial phenylene ethynylene oligomers. J Phys Chem B. 2008 Mar 20; 112(11):3495-502. PMID: 18293958.
      Citations: 24     Fields:    Translation:HumansCells
    98. Shunmugam R, Tew GN. Terpyridine-lanthanide complexes respond to fluorophosphate containing nerve gas G-agent surrogates. Chemistry. 2008; 14(18):5409-12. PMID: 18454436.
      Citations: 3     Fields:    
    99. Shunmugam R, Gabriel GJ, Smith CE, Aamer KA, Tew GN. A highly selective colorimetric aqueous sensor for mercury. Chemistry. 2008; 14(13):3904-7. PMID: 18348130.
      Citations: 5     Fields:    Translation:Cells
    100. Som A, Vemparala S, Ivanov I, Tew GN. Synthetic mimics of antimicrobial peptides. Biopolymers. 2008; 90(2):83-93. PMID: 18314892.
      Citations: 44     Fields:    Translation:AnimalsCells
    101. Gabriel GJ, Tew GN. Conformationally rigid proteomimetics: a case study in designing antimicrobial aryl oligomers. Org Biomol Chem. 2008 Feb 07; 6(3):417-23. PMID: 18219405.
      Citations: 6     Fields:    Translation:HumansCells
    102. Yang L, Gordon VD, Mishra A, Som A, Purdy KR, Davis MA, Tew GN, Wong GC. Synthetic antimicrobial oligomers induce a composition-dependent topological transition in membranes. J Am Chem Soc. 2007 Oct 10; 129(40):12141-7. PMID: 17880067.
      Citations: 38     Fields:    Translation:Cells
    103. Beckloff N, Laube D, Castro T, Furgang D, Park S, Perlin D, Clements D, Tang H, Scott RW, Tew GN, Diamond G. Activity of an antimicrobial peptide mimetic against planktonic and biofilm cultures of oral pathogens. Antimicrob Agents Chemother. 2007 Nov; 51(11):4125-32. PMID: 17785509.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    104. Gabriel GJ, Som A, Madkour AE, Eren T, Tew GN. Infectious Disease: Connecting Innate Immunity to Biocidal Polymers. Mater Sci Eng R Rep. 2007 Aug 01; 57(1-6):28-64. PMID: 18160969.
      Citations:    
    105. Zimberlin JA, Sanabria-DeLong N, Tew GN, Crosby AJ. Cavitation rheology for soft materials. Soft Matter. 2007 May 23; 3(6):763-767. PMID: 32900140.
      Citations: 13     Fields:    
    106. Agrawal SK, Sanabria-Delong N, Jemian PR, Tew GN, Bhatia SR. Micro- to nanoscale structure of biocompatible PLA-PEO-PLA hydrogels. Langmuir. 2007 Apr 24; 23(9):5039-44. PMID: 17397197.
      Citations: 8     Fields:    
    107. Slutsky MM, Jones TV, Tew GN. Spin system assignment of homo-o-phenylene ethynylene oligomers. J Org Chem. 2007 Jan 19; 72(2):342-7. PMID: 17221948.
      Citations:    Fields:    Translation:Cells
    108. Seo SH, Chang JY, Tew GN. Self-assembled vesicles from an amphiphilic ortho-phenylene ethynylene macrocycle. Angew Chem Int Ed Engl. 2006 Nov 20; 45(45):7526-30. PMID: 17001727.
      Citations: 7     Fields:    
    109. Ishitsuka Y, Arnt L, Majewski J, Frey S, Ratajczek M, Kjaer K, Tew GN, Lee KY. Amphiphilic poly(phenyleneethynylene)s can mimic antimicrobial peptide membrane disordering effect by membrane insertion. J Am Chem Soc. 2006 Oct 11; 128(40):13123-9. PMID: 17017792.
      Citations: 15     Fields:    Translation:Cells
    110. Seo SH, Tew GN, Chang JY. Lyotropic columnar liquid crystals based on polycatenar 1H-imidazole amphiphiles and their assembly into bundles at the surface of silicon. Soft Matter. 2006 Sep 19; 2(10):886-891. PMID: 32680280.
      Citations:    Fields:    
    111. Seo SH, Jones TV, Seyler H, Peters JO, Kim TH, Chang JY, Tew GN. Liquid crystalline order from ortho-phenylene ethynylene macrocycles. J Am Chem Soc. 2006 Jul 26; 128(29):9264-5. PMID: 16848425.
      Citations: 7     Fields:    
    112. N?sslein K, Arnt L, Rennie J, Owens C, Tew GN. Broad-spectrum antibacterial activity by a novel abiogenic peptide mimic. Microbiology (Reading). 2006 Jul; 152(Pt 7):1913-1918. PMID: 16804167.
      Citations: 17     Fields:    Translation:Humans
    113. Tang H, Doerksen RJ, Jones TV, Klein ML, Tew GN. Biomimetic facially amphiphilic antibacterial oligomers with conformationally stiff backbones. Chem Biol. 2006 Apr; 13(4):427-35. PMID: 16632255.
      Citations: 27     Fields:    Translation:HumansCells
    114. Tew GN, Clements D, Tang H, Arnt L, Scott RW. Antimicrobial activity of an abiotic host defense peptide mimic. Biochim Biophys Acta. 2006 Sep; 1758(9):1387-92. PMID: 16626628.
      Citations: 42     Fields:    Translation:AnimalsCells
    115. Kim T, Arnt L, Atkins E, Tew GN. Self-assembled structures with liquid-crystalline order in aqueous solution by patterning poly(phenylene ethynylene)s. Chemistry. 2006 Mar 08; 12(9):2423-7. PMID: 16453365.
      Citations: 2     Fields:    Translation:Cells
    116. Arnt L, Rennie JR, Linser S, Willumeit R, Tew GN. Membrane activity of biomimetic facially amphiphilic antibiotics. J Phys Chem B. 2006 Mar 02; 110(8):3527-32. PMID: 16494408.
      Citations: 13     Fields:    Translation:Cells
    117. Chen X, Tang H, Even MA, Wang J, Tew GN, Chen Z. Observing a molecular knife at work. J Am Chem Soc. 2006 Mar 01; 128(8):2711-4. PMID: 16492058.
      Citations: 19     Fields:    
    118. Agrawal SK, Sanabria-DeLong N, Coburn JM, Tew GN, Bhatia SR. Novel drug release profiles from micellar solutions of PLA-PEO-PLA triblock copolymers. J Control Release. 2006 May 01; 112(1):64-71. PMID: 16507325.
      Citations: 15     Fields:    Translation:Cells
    119. Jones TV, Slutsky MM, Laos R, de Greef TF, Tew GN. Solution 1H NMR confirmation of folding in short o-phenylene ethynylene oligomers. J Am Chem Soc. 2005 Dec 14; 127(49):17235-40. PMID: 16332071.
      Citations: 2     Fields:    Translation:Cells
    120. Shunmugam R, Tew GN. Unique emission from polymer based lanthanide alloys. J Am Chem Soc. 2005 Oct 05; 127(39):13567-72. PMID: 16190721.
      Citations: 5     Fields:    
    121. Harrington DA, Behanna HA, Tew GN, Claussen RC, Stupp SI. Supramolecular fluorophores for biological studies: phenylene vinylene-amino acid amphiphiles. Chem Biol. 2005 Oct; 12(10):1085-91. PMID: 16242651.
      Citations: 3     Fields:    Translation:AnimalsCells
    122. Tew GN, Sanabria-DeLong N, Agrawal SK, Bhatia SR. New properties from PLA-PEO-PLA hydrogels. Soft Matter. 2005 Sep 26; 1(4):253-258. PMID: 32646115.
      Citations: 1     Fields:    
    123. Rennie J, Arnt L, Tang H, N?sslein K, Tew GN. Simple oligomers as antimicrobial peptide mimics. J Ind Microbiol Biotechnol. 2005 Jul; 32(7):296-300. PMID: 15959729.
      Citations: 12     Fields:    Translation:Cells
    124. Tang H, Doerksen RJ, Tew GN. Synthesis of urea oligomers and their antibacterial activity. Chem Commun (Camb). 2005 Mar 28; (12):1537-9. PMID: 15770251.
      Citations: 19     Fields:    Translation:Cells
    125. Ilker MF, N?sslein K, Tew GN, Coughlin EB. Tuning the hemolytic and antibacterial activities of amphiphilic polynorbornene derivatives. J Am Chem Soc. 2004 Dec 08; 126(48):15870-5. PMID: 15571411.
      Citations: 83     Fields:    Translation:HumansCells
    126. Doerksen RJ, Chen B, Liu D, Tew GN, Degrado WF, Klein ML. Controlling the conformation of arylamides: computational studies of intramolecular hydrogen bonds between amides and ethers or thioethers. Chemistry. 2004 Oct 11; 10(20):5008-16. PMID: 15372664.
      Citations: 7     Fields:    Translation:Cells
    127. Aamer KA, Sardinha H, Bhatia SR, Tew GN. Rheological studies of PLLA-PEO-PLLA triblock copolymer hydrogels. Biomaterials. 2004 Mar; 25(6):1087-93. PMID: 14615174.
      Citations: 9     Fields:    
    128. Blatchly RA, Tew GN. Theoretical study of helix formation in substituted phenylene ethynylene oligomers. J Org Chem. 2003 Nov 14; 68(23):8780-5. PMID: 14604344.
      Citations:    Fields:    
    129. Jones TV, Blatchly RA, Tew GN. Synthesis of alkoxy-substituted ortho-phenylene ethynylene oligomers. Org Lett. 2003 Sep 04; 5(18):3297-9. PMID: 12943411.
      Citations: 2     Fields:    Translation:Cells
    130. Stigers DJ, Tew GN. Poly(3-hydroxyalkanoate)s functionalized with carboxylic acid groups in the side chain. Biomacromolecules. 2003 Mar-Apr; 4(2):193-5. PMID: 12625711.
      Citations: 5     Fields:    
    131. Arnt L, Tew GN. New poly(phenyleneethynylene)s with cationic, facially amphiphilic structures. J Am Chem Soc. 2002 Jul 03; 124(26):7664-5. PMID: 12083913.
      Citations: 19     Fields:    Translation:Cells
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