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Lisa M Minter BS, PhD

TitleProfessor
InstitutionUniversity of Massachusetts Amherst
DepartmentCollege of Natural Sciences
Address427K Integrated Sciences Building
Amherst, MA 01003
Phone413-545-6327
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zhang J, Walker ME, Sanidad KZ, Zhang H, Liang Y, Zhao E, Chacon-Vargas K, Yeliseyev V, Parsonnet J, Haggerty TD, Wang G, Simpson JB, Jariwala PB, Beaty VV, Yang J, Yang H, Panigrahy A, Minter LM, Kim D, Gibbons JG, Liu L, Li Z, Xiao H, Borlandelli V, Overkleeft HS, Cloer EW, Major MB, Goldfarb D, Cai Z, Redinbo MR, Zhang G. Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract. Nat Commun. 2022 01 10; 13(1):136. PMID: 35013263.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    2. Anastasiadou E, Minter LM, Felli MP. Editorial: Targeting Developmental Pathways in Inflammation and Disease. Front Cell Dev Biol. 2021; 9:791115. PMID: 34805190.
      Citations:    
    3. Trivedi P, Patel SK, Bellavia D, Messina E, Palermo R, Ceccarelli S, Marchese C, Anastasiadou E, Minter LM, Felli MP. When Viruses Cross Developmental Pathways. Front Cell Dev Biol. 2021; 9:691644. PMID: 34422814.
      Citations:    
    4. Hango CR, Backlund CM, Davis HC, Posey ND, Minter LM, Tew GN. Non-Covalent Carrier Hydrophobicity as a Universal Predictor of Intracellular Protein Activity. Biomacromolecules. 2021 07 12; 22(7):2850-2863. PMID: 34156837.
      Citations: 2     Fields:    
    5. Majumder S, Crabtree JS, Golde TE, Minter LM, Osborne BA, Miele L. Targeting Notch in oncology: the path forward. Nat Rev Drug Discov. 2021 02; 20(2):125-144. PMID: 33293690.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    6. Xie M, Yang J, Zhang J, Sherman HL, Zhang Z, Minter LM, Hammock BD, Park Y, Zhang G. Effects of Linoleic Acid-Rich Diet on Plasma Profiles of Eicosanoids and Development of Colitis in Il-10-/- Mice. J Agric Food Chem. 2020 Jul 22; 68(29):7641-7647. PMID: 32594738.
      Citations: 2     Fields:    Translation:HumansAnimals
    7. Ozay EI, Shanthalingam S, Torres JA, Osborne BA, Tew GN, Minter LM. Protein Kinase C Theta Modulates PCMT1 through hnRNPL to Regulate FOXP3 Stability in Regulatory T Cells. Mol Ther. 2020 10 07; 28(10):2220-2236. PMID: 32592691.
      Citations: 1     Fields:    Translation:Cells
    8. Ozay EI, Shanthalingam S, Sherman HL, Torres JA, Osborne BA, Tew GN, Minter LM. Cell-Penetrating Anti-Protein Kinase C Theta Antibodies Act Intracellularly to Generate Stable, Highly Suppressive Regulatory T Cells. Mol Ther. 2020 09 02; 28(9):1987-2006. PMID: 32492367.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    9. Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. ?-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse ?-secretase modulators do not. Alzheimers Res Ther. 2020 05 19; 12(1):61. PMID: 32430033.
      Citations: 1     Fields:    Translation:HumansCells
    10. Mitra A, Shanthalingam S, Sherman HL, Singh K, Canakci M, Torres JA, Lawlor R, Ran Y, Golde TE, Miele L, Thayumanavan S, Minter LM, Osborne BA. CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells. Front Immunol. 2020; 11:735. PMID: 32457739.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    11. Xie M, Zhang H, Wang W, Sherman HL, Minter LM, Cai Z, Zhang G. Triclocarban Exposure Exaggerates Spontaneous Colonic Inflammation in Il-10-/- Mice. Toxicol Sci. 2020 03 01; 174(1):92-99. PMID: 31868902.
      Citations: 5     Fields:    Translation:Animals
    12. Angelou CC, Wells AC, Vijayaraghavan J, Dougan CE, Lawlor R, Iverson E, Lazarevic V, Kimura MY, Peyton SR, Minter LM, Osborne BA, Pobezinskaya EL, Pobezinsky LA. Differentiation of Pathogenic Th17 Cells Is Negatively Regulated by Let-7 MicroRNAs in a Mouse Model of Multiple Sclerosis. Front Immunol. 2019; 10:3125. PMID: 32010153.
      Citations: 14     Fields:    Translation:AnimalsCells
    13. Backlund CM, Hango CR, Minter LM, Tew GN. Protein and Antibody Delivery into Difficult-to-Transfect Cells by Polymeric Peptide Mimics. ACS Appl Bio Mater. 2020 Jan 21; 3(1):180-185. PMID: 35019434.
      Citations: 1     Fields:    
    14. Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. Individual and combined presenilin 1 and 2 knockouts reveal that both have highly overlapping functions in HEK293T cells. J Biol Chem. 2019 07 19; 294(29):11276-11285. PMID: 31167792.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    15. Geiger S, Ozay EI, Geumann U, Hereth MK, Magnusson T, Shanthalingam S, Hirsch D, Kälin S, Günther C, Osborne BA, Tew GN, Hermann FG, Minter LM. Alpha-1 Antitrypsin-Expressing Mesenchymal Stromal Cells Confer a Long-Term Survival Benefit in a Mouse Model of Lethal GvHD. Mol Ther. 2019 08 07; 27(8):1436-1451. PMID: 31138510.
      Citations: 1     Fields:    Translation:AnimalsCells
    16. Backlund CM, Parhamifar L, Minter L, Tew GN, Andresen TL. Protein Transduction Domain Mimics Facilitate Rapid Antigen Delivery into Monocytes. Mol Pharm. 2019 06 03; 16(6):2462-2469. PMID: 31095395.
      Citations:    Fields:    Translation:HumansCells
    17. Sorrentino C, Hossain F, Rodriguez PC, Sierra RA, Pannuti A, Hatfield S, Osborne BA, Minter LM, Miele L, Morello S. Corrigendum: Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells. Front Immunol. 2019; 10:935. PMID: 31130947.
      Citations:    Fields:    
    18. Wang W, Yang J, Edin ML, Wang Y, Luo Y, Wan D, Yang H, Song CQ, Xue W, Sanidad KZ, Song M, Bisbee HA, Bradbury JA, Nan G, Zhang J, Shih PB, Lee KSS, Minter LM, Kim D, Xiao H, Liu JY, Hammock BD, Zeldin DC, Zhang G. Targeted Metabolomics Identifies the Cytochrome P450 Monooxygenase Eicosanoid Pathway as a Novel Therapeutic Target of Colon Tumorigenesis. Cancer Res. 2019 04 15; 79(8):1822-1830. PMID: 30803995.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    19. Sorrentino C, Hossain F, Rodriguez PC, Sierra RA, Pannuti A, Osborne BA, Minter LM, Miele L, Morello S. Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells. Front Immunol. 2019; 10:162. PMID: 30792717.
      Citations: 19     Fields:    
    20. Ozay EI, Vijayaraghavan J, Gonzalez-Perez G, Shanthalingam S, Sherman HL, Garrigan DT, Chandiran K, Torres JA, Osborne BA, Tew GN, Slukvin II, Macdonald RA, Kelly K, Minter LM. Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease. Stem Cell Res. 2019 03; 35:101401. PMID: 30738321.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    21. Hossain F, Sorrentino C, Ucar DA, Peng Y, Matossian M, Wyczechowska D, Crabtree J, Zabaleta J, Morello S, Del Valle L, Burow M, Collins-Burow B, Pannuti A, Minter LM, Golde TE, Osborne BA, Miele L. Notch Signaling Regulates Mitochondrial Metabolism and NF-?B Activity in Triple-Negative Breast Cancer Cells via IKK?-Dependent Non-canonical Pathways. Front Oncol. 2018; 8:575. PMID: 30564555.
      Citations:    
    22. Sgolastra F, Kuksin CA, Gonzalez-Perez G, Minter LM, Tew GN. Enhanced TAT-Cre Protein Transduction for Efficient Gene Recombination in T cells. ACS Appl Bio Mater. 2018 Aug 20; 1(2):444-451. PMID: 35016365.
      Citations:    Fields:    
    23. Posey ND, Hango CR, Minter LM, Tew GN. The Role of Cargo Binding Strength in Polymer-Mediated Intracellular Protein Delivery. Bioconjug Chem. 2018 08 15; 29(8):2679-2690. PMID: 30080401.
      Citations: 3     Fields:    Translation:HumansCells
    24. Ozay EI, Sherman HL, Mello V, Trombley G, Lerman A, Tew GN, Yadava N, Minter LM. Rotenone Treatment Reveals a Role for Electron Transport Complex I in the Subcellular Localization of Key Transcriptional Regulators During T Helper Cell Differentiation. Front Immunol. 2018; 9:1284. PMID: 29930555.
      Citations: 1     Fields:    Translation:AnimalsCells
    25. Hossain F, Majumder S, Ucar DA, Rodriguez PC, Golde TE, Minter LM, Osborne BA, Miele L. Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses. Front Immunol. 2018; 9:1288. PMID: 29915603.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    26. Sanidad KZ, Yang H, Wang W, Ozay EI, Yang J, Gu M, Karner E, Zhang J, Kim D, Minter LM, Xiao H, Zhang G. Effects of Consumer Antimicrobials Benzalkonium Chloride, Benzethonium Chloride, and Chloroxylenol on Colonic Inflammation and Colitis-Associated Colon Tumorigenesis in Mice. Toxicol Sci. 2018 06 01; 163(2):490-499. PMID: 29514330.
      Citations: 4     Fields:    Translation:AnimalsPHPublic Health
    27. Yang H, Wang W, Romano KA, Gu M, Sanidad KZ, Kim D, Yang J, Schmidt B, Panigrahy D, Pei R, Martin DA, Ozay EI, Wang Y, Song M, Bolling BW, Xiao H, Minter LM, Yang GY, Liu Z, Rey FE, Zhang G. A common antimicrobial additive increases colonic inflammation and colitis-associated colon tumorigenesis in mice. Sci Transl Med. 2018 05 30; 10(443). PMID: 29848663.
      Citations: 33     Fields:    Translation:AnimalsCells
    28. Chandiran K, Lawlor R, Pannuti A, Perez GG, Srinivasan J, Golde TE, Miele L, Osborne BA, Minter LM. Notch1 primes CD4 T cells for T helper type I differentiation through its early effects on miR-29. Mol Immunol. 2018 07; 99:191-198. PMID: 29807327.
      Citations: 10     Fields:    Translation:AnimalsCells
    29. Ran Y, Hossain F, Pannuti A, Lessard CB, Ladd GZ, Jung JI, Minter LM, Osborne BA, Miele L, Golde TE. ?-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct. EMBO Mol Med. 2017 07; 9(7):950-966. PMID: 28539479.
      Citations: 65     Fields:    Translation:HumansCells
    30. Sarapas JM, Backlund CM, deRonde BM, Minter LM, Tew GN. ROMP- and RAFT-Based Guanidinium-Containing Polymers as Scaffolds for Protein Mimic Synthesis. Chemistry. 2017 May 17; 23(28):6858-6863. PMID: 28370636.
      Citations: 4     Fields:    Translation:HumansCells
    31. Sgolastra F, Backlund CM, Ilker Ozay E, deRonde BM, Minter LM, Tew GN. Sequence segregation improves non-covalent protein delivery. J Control Release. 2017 05 28; 254:131-136. PMID: 28363520.
      Citations: 8     Fields:    Translation:HumansCells
    32. Backlund CM, Sgolastra F, Otter R, Minter L, Takeuchi T, Futaki S, Tew GN. Increased Hydrophobic Block Length of PTDMs Promotes Protein Internalization. Polym Chem. 2016 Dec 28; 7(48):7514-7521. PMID: 29093759.
      Citations:    
    33. Caffrey LM, deRonde BM, Minter LM, Tew GN. Mapping Optimal Charge Density and Length of ROMP-Based PTDMs for siRNA Internalization. Biomacromolecules. 2016 10 10; 17(10):3205-3212. PMID: 27599388.
      Citations: 5     Fields:    Translation:HumansCells
    34. Ozay EI, Gonzalez-Perez G, Torres JA, Vijayaraghavan J, Lawlor R, Sherman HL, Garrigan DT, Burnside AS, Osborne BA, Tew GN, Minter LM. Intracellular Delivery of Anti-pPKC? (Thr538) via Protein Transduction Domain Mimics for Immunomodulation. Mol Ther. 2016 Dec; 24(12):2118-2130. PMID: 27633441.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    35. deRonde BM, Posey ND, Otter R, Caffrey LM, Minter LM, Tew GN. Optimal Hydrophobicity in Ring-Opening Metathesis Polymerization-Based Protein Mimics Required for siRNA Internalization. Biomacromolecules. 2016 06 13; 17(6):1969-77. PMID: 27103189.
      Citations: 9     Fields:    Translation:HumansCells
    36. deRonde BM, Torres JA, Minter LM, Tew GN. Development of Guanidinium-Rich Protein Mimics for Efficient siRNA Delivery into Human T Cells. Biomacromolecules. 2015 Oct 12; 16(10):3172-9. PMID: 26324222.
      Citations: 10     Fields:    Translation:HumansCells
    37. Kuksin CA, Minter LM. The Link between Autoimmunity and Lymphoma: Does NOTCH Signaling Play a Contributing Role? Front Oncol. 2015; 5:51. PMID: 25759795.
      Citations:    
    38. Arieta Kuksin C, Gonzalez-Perez G, Minter LM. CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia. Blood. 2015 Mar 26; 125(13):2087-94. PMID: 25647836.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    39. Shin HM, Tilahun ME, Cho OH, Chandiran K, Kuksin CA, Keerthivasan S, Fauq AH, Golde TE, Miele L, Thome M, Osborne BA, Minter LM. NOTCH1 Can Initiate NF-?B Activation via Cytosolic Interactions with Components of the T Cell Signalosome. Front Immunol. 2014; 5:249. PMID: 24904593.
      Citations: 24     Fields:    
    40. Sgolastra F, Minter LM, Osborne BA, Tew GN. Importance of sequence specific hydrophobicity in synthetic protein transduction domain mimics. Biomacromolecules. 2014 Mar 10; 15(3):812-20. PMID: 24506414.
      Citations: 13     Fields:    Translation:HumansCells
    41. Dongre A, Surampudi L, Lawlor RG, Fauq AH, Miele L, Golde TE, Minter LM, Osborne BA. Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells. Front Immunol. 2014; 5:54. PMID: 24611064.
      Citations: 32     Fields:    
    42. Minter LM. NOTCH signaling in immune-mediated bone marrow failure of aplastic anemia. Rare Dis. 2013; 1:e26764. PMID: 25003012.
      Citations:    
    43. Roderick JE, Gonzalez-Perez G, Kuksin CA, Dongre A, Roberts ER, Srinivasan J, Andrzejewski C, Fauq AH, Golde TE, Miele L, Minter LM. Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia. J Exp Med. 2013 Jul 01; 210(7):1311-29. PMID: 23733784.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    44. Tezgel AÖ, Gonzalez-Perez G, Telfer JC, Osborne BA, Minter LM, Tew GN. Novel protein transduction domain mimics as nonviral delivery vectors for siRNA targeting NOTCH1 in primary human T cells. Mol Ther. 2013 Jan; 21(1):201-9. PMID: 23070119.
      Citations: 23     Fields:    Translation:HumansCells
    45. Das P, Verbeeck C, Minter L, Chakrabarty P, Felsenstein K, Kukar T, Maharvi G, Fauq A, Osborne BA, Golde TE. Transient pharmacologic lowering of A? production prior to deposition results in sustained reduction of amyloid plaque pathology. Mol Neurodegener. 2012 Aug 14; 7:39. PMID: 22892055.
      Citations: 25     Fields:    Translation:HumansAnimals
    46. Minter LM, Osborne BA. Notch and the survival of regulatory T cells: location is everything! Sci Signal. 2012 Jul 24; 5(234):pe31. PMID: 22827995.
      Citations: 3     Fields:    Translation:Cells
    47. Minter LM, Osborne BA. Canonical and non-canonical Notch signaling in CD4? T cells. Curr Top Microbiol Immunol. 2012; 360:99-114. PMID: 22695917.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    48. Keerthivasan S, Suleiman R, Lawlor R, Roderick J, Bates T, Minter L, Anguita J, Juncadella I, Nickoloff BJ, Le Poole IC, Miele L, Osborne BA. Notch signaling regulates mouse and human Th17 differentiation. J Immunol. 2011 Jul 15; 187(2):692-701. PMID: 21685328.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    49. Cho OH, Shin HM, Miele L, Golde TE, Fauq A, Minter LM, Osborne BA. Notch regulates cytolytic effector function in CD8+ T cells. J Immunol. 2009 Mar 15; 182(6):3380-9. PMID: 19265115.
      Citations: 59     Fields:    Translation:AnimalsCells
    50. Joshi I, Minter LM, Telfer J, Demarest RM, Capobianco AJ, Aster JC, Sicinski P, Fauq A, Golde TE, Osborne BA. Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases. Blood. 2009 Feb 19; 113(8):1689-98. PMID: 19001083.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    51. Samon JB, Champhekar A, Minter LM, Telfer JC, Miele L, Fauq A, Das P, Golde TE, Osborne BA. Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood. 2008 Sep 01; 112(5):1813-21. PMID: 18550850.
      Citations: 87     Fields:    Translation:AnimalsCells
    52. Osborne BA, Minter LM. Notch signalling during peripheral T-cell activation and differentiation. Nat Rev Immunol. 2007 Jan; 7(1):64-75. PMID: 17170755.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    53. Shin HM, Minter LM, Cho OH, Gottipati S, Fauq AH, Golde TE, Sonenshein GE, Osborne BA. Notch1 augments NF-kappaB activity by facilitating its nuclear retention. EMBO J. 2006 Jan 11; 25(1):129-38. PMID: 16319921.
      Citations: 125     Fields:    Translation:AnimalsCells
    54. Minter LM, Turley DM, Das P, Shin HM, Joshi I, Lawlor RG, Cho OH, Palaga T, Gottipati S, Telfer JC, Kostura L, Fauq AH, Simpson K, Such KA, Miele L, Golde TE, Miller SD, Osborne BA. Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nat Immunol. 2005 Jul; 6(7):680-8. PMID: 15991363.
      Citations: 136     Fields:    Translation:AnimalsCells
    55. Benson RM, Minter LM, Osborne BA, Granowitz EV. Hyperbaric oxygen inhibits stimulus-induced proinflammatory cytokine synthesis by human blood-derived monocyte-macrophages. Clin Exp Immunol. 2003 Oct; 134(1):57-62. PMID: 12974755.
      Citations: 36     Fields:    Translation:HumansCells
    56. Minter LM, Osborne BA. Cell death in the thymus--it' s all a matter of contacts. Semin Immunol. 2003 Jun; 15(3):135-44. PMID: 14563112.
      Citations: 5     Fields:    Translation:HumansAnimals
    57. Minter LM, Dickinson ES, Naber SP, Jerry DJ. Epithelial cell cycling predicts p53 responsiveness to gamma-irradiation during post-natal mammary gland development. Development. 2002 Jun; 129(12):2997-3008. PMID: 12050146.
      Citations: 8     Fields:    Translation:AnimalsCells
    58. Jerry DJ, Minter LM, Becker KA, Blackburn AC. Hormonal control of p53 and chemoprevention. Breast Cancer Res. 2002; 4(3):91-4. PMID: 12052250.
      Citations: 1     Fields:    Translation:Humans
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