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Lisa M Minter BS, PhD

TitleProfessor
InstitutionUniversity of Massachusetts Amherst
DepartmentCollege of Natural Sciences
Address427K Integrated Sciences Building
Amherst, MA 01003
Phone413-545-6327
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. Individual and combined presenilin 1 and 2 knockouts reveal that both have highly overlapping functions in HEK293T cells. J Biol Chem. 2019 Jun 05. PMID: 31167792.
      View in: PubMed
    2. Geiger S, Ozay EI, Geumann U, Hereth MK, Magnusson T, Shanthalingam S, Hirsch D, Kälin S, Günther C, Osborne BA, Tew GN, Hermann FG, Minter LM. Alpha-1 Antitrypsin-Expressing Mesenchymal Stromal Cells Confer a Long-Term Survival Benefit in a Mouse Model of Lethal GvHD. Mol Ther. 2019 May 16. PMID: 31138510.
      View in: PubMed
    3. Backlund CM, Parhamifar L, Minter L, Tew GN, Andresen TL. Protein Transduction Domain Mimics Facilitate Rapid Antigen Delivery into Monocytes. Mol Pharm. 2019 May 16. PMID: 31095395.
      View in: PubMed
    4. Sorrentino C, Hossain F, Rodriguez PC, Sierra RA, Pannuti A, Hatfield S, Osborne BA, Minter LM, Miele L, Morello S. Corrigendum: Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells. Front Immunol. 2019; 10:935. PMID: 31130947.
      View in: PubMed
    5. Wang W, Yang J, Edin ML, Wang Y, Luo Y, Wan D, Yang H, Song CQ, Xue W, Sanidad KZ, Song M, Bisbee HA, Bradbury JA, Nan G, Zhang J, Shih PB, Lee KSS, Minter LM, Kim D, Xiao H, Liu JY, Hammock BD, Zeldin DC, Zhang G. Targeted metabolomics identifies the cytochrome P450 monooxygenase eicosanoid pathway as a novel therapeutic target of colon tumorigenesis. Cancer Res. 2019 Feb 25. PMID: 30803995.
      View in: PubMed
    6. Sorrentino C, Hossain F, Rodriguez PC, Sierra RA, Pannuti A, Osborne BA, Minter LM, Miele L, Morello S. Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells. Front Immunol. 2019; 10:162. PMID: 30792717.
      View in: PubMed
    7. Ozay EI, Vijayaraghavan J, Gonzalez-Perez G, Shanthalingam S, Sherman HL, Garrigan DT, Chandiran K, Torres JA, Osborne BA, Tew GN, Slukvin II, Macdonald RA, Kelly K, Minter LM. Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease. Stem Cell Res. 2019 Feb 01; 35:101401. PMID: 30738321.
      View in: PubMed
    8. Hossain F, Sorrentino C, Ucar DA, Peng Y, Matossian M, Wyczechowska D, Crabtree J, Zabaleta J, Morello S, Del Valle L, Burow M, Collins-Burow B, Pannuti A, Minter LM, Golde TE, Osborne BA, Miele L. Notch Signaling Regulates Mitochondrial Metabolism and NF-?B Activity in Triple-Negative Breast Cancer Cells via IKKa-Dependent Non-canonical Pathways. Front Oncol. 2018; 8:575. PMID: 30564555.
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    9. Posey ND, Hango CR, Minter LM, Tew GN. The Role of Cargo Binding Strength in Polymer-Mediated Intracellular Protein Delivery. Bioconjug Chem. 2018 Aug 06. PMID: 30080401.
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    10. Ozay EI, Sherman HL, Mello V, Trombley G, Lerman A, Tew GN, Yadava N, Minter LM. Rotenone Treatment Reveals a Role for Electron Transport Complex I in the Subcellular Localization of Key Transcriptional Regulators During T Helper Cell Differentiation. Front Immunol. 2018; 9:1284. PMID: 29930555.
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    11. Hossain F, Majumder S, Ucar DA, Rodriguez PC, Golde TE, Minter LM, Osborne BA, Miele L. Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses. Front Immunol. 2018; 9:1288. PMID: 29915603.
      View in: PubMed
    12. Sanidad KZ, Yang H, Wang W, Ozay EI, Yang J, Gu M, Karner E, Zhang J, Kim D, Minter LM, Xiao H, Zhang G. Effects of Consumer Antimicrobials Benzalkonium Chloride, Benzethonium Chloride, and Chloroxylenol on Colonic Inflammation and Colitis-Associated Colon Tumorigenesis in Mice. Toxicol Sci. 2018 Jun 01; 163(2):490-499. PMID: 29514330.
      View in: PubMed
    13. Yang H, Wang W, Romano KA, Gu M, Sanidad KZ, Kim D, Yang J, Schmidt B, Panigrahy D, Pei R, Martin DA, Ozay EI, Wang Y, Song M, Bolling BW, Xiao H, Minter LM, Yang GY, Liu Z, Rey FE, Zhang G. A common antimicrobial additive increases colonic inflammation and colitis-associated colon tumorigenesis in mice. Sci Transl Med. 2018 May 30; 10(443). PMID: 29848663.
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    14. Chandiran K, Lawlor R, Pannuti A, Perez GG, Srinivasan J, Golde TE, Miele L, Osborne BA, Minter LM. Notch1 primes CD4 T cells for T helper type I differentiation through its early effects on miR-29. Mol Immunol. 2018 Jul; 99:191-198. PMID: 29807327.
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    15. Ran Y, Hossain F, Pannuti A, Lessard CB, Ladd GZ, Jung JI, Minter LM, Osborne BA, Miele L, Golde TE. ?-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct. EMBO Mol Med. 2017 May 24. PMID: 28539479.
      View in: PubMed
    16. Sgolastra F, Backlund CM, Ilker Ozay E, deRonde BM, Minter LM, Tew GN. Sequence segregation improves non-covalent protein delivery. J Control Release. 2017 Mar 28. PMID: 28363520.
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    17. Tew GN, Sarpas JM, Backland CM, deRonde BM, Minter LM. ROMP- and RAFT-based Guanidinium-containing Polymers as Scaffolds for Protein Mimic Synthesis. Chemistry. 2017 Mar 28. PMID: 28370636.
      View in: PubMed
    18. Backlund CM, Sgolastra F, Otter R, Minter L, Takeuchi T, Futaki S, Tew GN. Increased Hydrophobic Block Length of PTDMs Promotes Protein Internalization. Polym Chem. 2016 Dec 28; 7(48):7514-7521. PMID: 29093759.
      View in: PubMed
    19. Caffrey LM, deRonde BM, Minter LM, Tew GN. Mapping Optimal Charge Density and Length of ROMP-Based PTDMs for siRNA Internalization. Biomacromolecules. 2016 Oct 10; 17(10):3205-3212. PMID: 27599388.
      View in: PubMed
    20. Ozay EI, Gonzalez-Perez G, Torres JA, Vijayaraghavan J, Lawlor R, Sherman HL, Garrigan DT, Burnside AS, Osborne BA, Tew GN, Minter LM. Intracellular Delivery of Anti-pPKC? (Thr538) via Protein Transduction Domain Mimics for Immunomodulation. Mol Ther. 2016 Dec; 24(12):2118-2130. PMID: 27633441.
      View in: PubMed
    21. deRonde BM, Posey ND, Otter R, Caffrey LM, Minter LM, Tew GN. Optimal Hydrophobicity in Ring-Opening Metathesis Polymerization-Based Protein Mimics Required for siRNA Internalization. Biomacromolecules. 2016 Jun 13; 17(6):1969-77. PMID: 27103189.
      View in: PubMed
    22. deRonde BM, Torres JA, Minter LM, Tew GN. Development of Guanidinium-Rich Protein Mimics for Efficient siRNA Delivery into Human T Cells. Biomacromolecules. 2015 Oct 12; 16(10):3172-9. PMID: 26324222.
      View in: PubMed
    23. Kuksin CA, Minter LM. The Link between Autoimmunity and Lymphoma: Does NOTCH Signaling Play a Contributing Role? Front Oncol. 2015; 5:51. PMID: 25759795.
      View in: PubMed
    24. Arieta Kuksin C, Gonzalez-Perez G, Minter LM. CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia. Blood. 2015 Mar 26; 125(13):2087-94. PMID: 25647836.
      View in: PubMed
    25. Shin HM, Tilahun ME, Cho OH, Chandiran K, Kuksin CA, Keerthivasan S, Fauq AH, Golde TE, Miele L, Thome M, Osborne BA, Minter LM. NOTCH1 Can Initiate NF-?B Activation via Cytosolic Interactions with Components of the T Cell Signalosome. Front Immunol. 2014; 5:249. PMID: 24904593.
      View in: PubMed
    26. Sgolastra F, Minter LM, Osborne BA, Tew GN. Importance of sequence specific hydrophobicity in synthetic protein transduction domain mimics. Biomacromolecules. 2014 Mar 10; 15(3):812-20. PMID: 24506414.
      View in: PubMed
    27. Dongre A, Surampudi L, Lawlor RG, Fauq AH, Miele L, Golde TE, Minter LM, Osborne BA. Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells. Front Immunol. 2014; 5:54. PMID: 24611064.
      View in: PubMed
    28. Minter LM. NOTCH signaling in immune-mediated bone marrow failure of aplastic anemia. Rare Dis. 2013; 1:e26764. PMID: 25003012.
      View in: PubMed
    29. Roderick JE, Gonzalez-Perez G, Kuksin CA, Dongre A, Roberts ER, Srinivasan J, Andrzejewski C, Fauq AH, Golde TE, Miele L, Minter LM. Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia. J Exp Med. 2013 Jul 1; 210(7):1311-29. PMID: 23733784.
      View in: PubMed
    30. Tezgel AÖ, Gonzalez-Perez G, Telfer JC, Osborne BA, Minter LM, Tew GN. Novel protein transduction domain mimics as nonviral delivery vectors for siRNA targeting NOTCH1 in primary human T cells. Mol Ther. 2013 Jan; 21(1):201-9. PMID: 23070119.
      View in: PubMed
    31. Das P, Verbeeck C, Minter L, Chakrabarty P, Felsenstein K, Kukar T, Maharvi G, Fauq A, Osborne BA, Golde TE. Transient pharmacologic lowering of Aß production prior to deposition results in sustained reduction of amyloid plaque pathology. Mol Neurodegener. 2012 Aug 14; 7:39. PMID: 22892055.
      View in: PubMed
    32. Minter LM, Osborne BA. Notch and the survival of regulatory T cells: location is everything! Sci Signal. 2012 Jul 24; 5(234):pe31. PMID: 22827995.
      View in: PubMed
    33. Minter LM, Osborne BA. Canonical and non-canonical Notch signaling in CD4? T cells. Curr Top Microbiol Immunol. 2012; 360:99-114. PMID: 22695917.
      View in: PubMed
    34. Keerthivasan S, Suleiman R, Lawlor R, Roderick J, Bates T, Minter L, Anguita J, Juncadella I, Nickoloff BJ, Le Poole IC, Miele L, Osborne BA. Notch signaling regulates mouse and human Th17 differentiation. J Immunol. 2011 Jul 15; 187(2):692-701. PMID: 21685328.
      View in: PubMed
    35. Cho OH, Shin HM, Miele L, Golde TE, Fauq A, Minter LM, Osborne BA. Notch regulates cytolytic effector function in CD8+ T cells. J Immunol. 2009 Mar 15; 182(6):3380-9. PMID: 19265115.
      View in: PubMed
    36. Joshi I, Minter LM, Telfer J, Demarest RM, Capobianco AJ, Aster JC, Sicinski P, Fauq A, Golde TE, Osborne BA. Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases. Blood. 2009 Feb 19; 113(8):1689-98. PMID: 19001083.
      View in: PubMed
    37. Samon JB, Champhekar A, Minter LM, Telfer JC, Miele L, Fauq A, Das P, Golde TE, Osborne BA. Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood. 2008 Sep 1; 112(5):1813-21. PMID: 18550850.
      View in: PubMed
    38. Osborne BA, Minter LM. Notch signalling during peripheral T-cell activation and differentiation. Nat Rev Immunol. 2007 Jan; 7(1):64-75. PMID: 17170755.
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    39. Shin HM, Minter LM, Cho OH, Gottipati S, Fauq AH, Golde TE, Sonenshein GE, Osborne BA. Notch1 augments NF-kappaB activity by facilitating its nuclear retention. EMBO J. 2006 Jan 11; 25(1):129-38. PMID: 16319921.
      View in: PubMed
    40. Minter LM, Turley DM, Das P, Shin HM, Joshi I, Lawlor RG, Cho OH, Palaga T, Gottipati S, Telfer JC, Kostura L, Fauq AH, Simpson K, Such KA, Miele L, Golde TE, Miller SD, Osborne BA. Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nat Immunol. 2005 Jul; 6(7):680-8. PMID: 15991363.
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    41. Benson RM, Minter LM, Osborne BA, Granowitz EV. Hyperbaric oxygen inhibits stimulus-induced proinflammatory cytokine synthesis by human blood-derived monocyte-macrophages. Clin Exp Immunol. 2003 Oct; 134(1):57-62. PMID: 12974755.
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    42. Minter LM, Osborne BA. Cell death in the thymus--it' s all a matter of contacts. Semin Immunol. 2003 Jun; 15(3):135-44. PMID: 14563112.
      View in: PubMed
    43. Minter LM, Dickinson ES, Naber SP, Jerry DJ. Epithelial cell cycling predicts p53 responsiveness to gamma-irradiation during post-natal mammary gland development. Development. 2002 Jun; 129(12):2997-3008. PMID: 12050146.
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    44. Jerry DJ, Minter LM, Becker KA, Blackburn AC. Hormonal control of p53 and chemoprevention. Breast Cancer Res. 2002; 4(3):91-4. PMID: 12052250.
      View in: PubMed
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