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Craig T Martin BA, PhD

TitleDepartment Head
InstitutionUniversity of Massachusetts Amherst
DepartmentCollege of Natural Sciences
Address122 Lederle Graduate Research Center
Amherst, MA 01003
Phone(413) 545-3299
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Gholamalipour Y, Johnson WC, Martin CT. Efficient inhibition of RNA self-primed extension by addition of competing 3'-capture DNA-improved RNA synthesis by T7 RNA polymerase. Nucleic Acids Res. 2019 Aug 08. PMID: 31392994.
      View in: PubMed
    2. Gholamalipour Y, Karunanayake Mudiyanselage A, Martin CT. 3' end additions by T7 RNA polymerase are RNA self-templated, distributive and diverse in character-RNA-Seq analyses. Nucleic Acids Res. 2018 Sep 14. PMID: 30219859.
      View in: PubMed
    3. Martin CT, Theis K. Closed for business: exit-channel coupling to active site conformation in bacterial RNA polymerase. Nat Struct Mol Biol. 2014 Sep; 21(9):741-2. PMID: 25192262.
      View in: PubMed
    4. Samanta S, Martin CT. Insights into the mechanism of initial transcription in Escherichia coli RNA polymerase. J Biol Chem. 2013 Nov 01; 288(44):31993-2003. PMID: 24047893.
      View in: PubMed
    5. Ramírez-Tapia LE, Martin CT. New insights into the mechanism of initial transcription: the T7 RNA polymerase mutant P266L transitions to elongation at longer RNA lengths than wild type. J Biol Chem. 2012 Oct 26; 287(44):37352-61. PMID: 22923611.
      View in: PubMed
    6. Vahia AV, Martin CT. Direct tests of the energetic basis of abortive cycling in transcription. Biochemistry. 2011 Aug 16; 50(32):7015-22. PMID: 21776950.
      View in: PubMed
    7. Liu X, Martin CT. Transcription elongation complex stability: the topological lock. J Biol Chem. 2009 Dec 25; 284(52):36262-70. PMID: 19846559.
      View in: PubMed
    8. Zhou Y, Navaroli DM, Enuameh MS, Martin CT. Dissociation of halted T7 RNA polymerase elongation complexes proceeds via a forward-translocation mechanism. Proc Natl Acad Sci U S A. 2007 Jun 19; 104(25):10352-7. PMID: 17553968.
      View in: PubMed
    9. Turingan RS, Theis K, Martin CT. Twisted or shifted? Fluorescence measurements of late intermediates in transcription initiation by T7 RNA polymerase. Biochemistry. 2007 May 29; 46(21):6165-8. PMID: 17472344.
      View in: PubMed
    10. Turingan RS, Liu C, Hawkins ME, Martin CT. Structural confirmation of a bent and open model for the initiation complex of T7 RNA polymerase. Biochemistry. 2007 Feb 20; 46(7):1714-23. PMID: 17253774.
      View in: PubMed
    11. Zhou Y, Martin CT. Observed instability of T7 RNA polymerase elongation complexes can be dominated by collision-induced "bumping". J Biol Chem. 2006 Aug 25; 281(34):24441-8. PMID: 16816387.
      View in: PubMed
    12. Gong P, Martin CT. Mechanism of instability in abortive cycling by T7 RNA polymerase. J Biol Chem. 2006 Aug 18; 281(33):23533-44. PMID: 16790422.
      View in: PubMed
    13. Han G, You CC, Kim BJ, Turingan RS, Forbes NS, Martin CT, Rotello VM. Light-regulated release of DNA and its delivery to nuclei by means of photolabile gold nanoparticles. Angew Chem Int Ed Engl. 2006 May 5; 45(19):3165-9. PMID: 16572498.
      View in: PubMed
    14. Han G, Martin CT, Rotello VM. Stability of gold nanoparticle-bound DNA toward biological, physical, and chemical agents. Chem Biol Drug Des. 2006 Jan; 67(1):78-82. PMID: 16492152.
      View in: PubMed
    15. Han G, Chari NS, Verma A, Hong R, Martin CT, Rotello VM. Controlled recovery of the transcription of nanoparticle-bound DNA by intracellular concentrations of glutathione. Bioconjug Chem. 2005 Nov-Dec; 16(6):1356-9. PMID: 16287230.
      View in: PubMed
    16. Martin CT, Esposito EA, Theis K, Gong P. Structure and function in promoter escape by T7 RNA polymerase. Prog Nucleic Acid Res Mol Biol. 2005; 80:323-47. PMID: 16164978.
      View in: PubMed
    17. Theis K, Gong P, Martin CT. Topological and conformational analysis of the initiation and elongation complex of t7 RNA polymerase suggests a new twist. Biochemistry. 2004 Oct 12; 43(40):12709-15. PMID: 15461442.
      View in: PubMed
    18. Gong P, Esposito EA, Martin CT. Initial bubble collapse plays a key role in the transition to elongation in T7 RNA polymerase. J Biol Chem. 2004 Oct 22; 279(43):44277-85. PMID: 15337752.
      View in: PubMed
    19. Esposito EA, Martin CT. Cross-linking of promoter DNA to T7 RNA polymerase does not prevent formation of a stable elongation complex. J Biol Chem. 2004 Oct 22; 279(43):44270-6. PMID: 15304497.
      View in: PubMed
    20. Martin CT, Ujvári A, Liu C. Evaluation of fluorescence spectroscopy methods for mapping melted regions of DNA along the transcription pathway. Methods Enzymol. 2003; 371:13-33. PMID: 14712689.
      View in: PubMed
    21. Kuzmine I, Gottlieb PA, Martin CT. Binding of the priming nucleotide in the initiation of transcription by T7 RNA polymerase. J Biol Chem. 2003 Jan 31; 278(5):2819-23. PMID: 12427761.
      View in: PubMed
    22. Liu C, Martin CT. Promoter clearance by T7 RNA polymerase. Initial bubble collapse and transcript dissociation monitored by base analog fluorescence. J Biol Chem. 2002 Jan 25; 277(4):2725-31. PMID: 11694519.
      View in: PubMed
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