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Sam R Nugen BS, MS, PhD

TitleAssistant Professor
InstitutionUniversity of Massachusetts Amherst
DepartmentCollege of Natural Sciences
Address246 Chenoweth Laboratory
Amherst, MA 01003
Phone413.545.1025
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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Singh S, Hinkley T, Nugen SR, Talbert JN. Colorimetric detection of Escherichia coli using engineered bacteriophage and an affinity reporter system. Anal Bioanal Chem. 2019 Sep 11. PMID: 31511947.
      View in: PubMed
    2. Pulkkinen EM, Hinkley TC, Nugen SR. Utilizing in vitro DNA assembly to engineer a synthetic T7 Nanoluc reporter phage for Escherichia coli detection. Integr Biol (Camb). 2019 Mar 30. PMID: 30927414.
      View in: PubMed
    3. Chen J, Nugen SR. Detection of protease and engineered phage-infected bacteria using peptide-graphene oxide nanosensors. Anal Bioanal Chem. 2019 Mar 23. PMID: 30903224.
      View in: PubMed
    4. Wang D, Hinkley T, Chen J, Talbert JN, Nugen SR. Phage based electrochemical detection of Escherichia coli in drinking water using affinity reporter probes. Analyst. 2018 Dec 19. PMID: 30564809.
      View in: PubMed
    5. Hinkley TC, Singh S, Garing S, Le Ny AM, Nichols KP, Peters JE, Talbert JN, Nugen SR. A phage-based assay for the rapid, quantitative, and single CFU visualization of E. coli (ECOR #13) in drinking water. Sci Rep. 2018 Oct 02; 8(1):14630. PMID: 30279488.
      View in: PubMed
    6. Hinkley TC, Garing S, Singh S, Le Ny AM, Nichols KP, Peters JE, Talbert JN, Nugen SR. Reporter bacteriophage T7NLC utilizes a novel NanoLuc::CBM fusion for the ultrasensitive detection of Escherichia coli in water. Analyst. 2018 Aug 20; 143(17):4074-4082. PMID: 30069563.
      View in: PubMed
    7. Chen J, Picard RA, Wang D, Nugen SR. Lyophilized Engineered Phages for Escherichia coli Detection in Food Matrices. ACS Sens. 2017 Nov 22; 2(11):1573-1577. PMID: 29043791.
      View in: PubMed
    8. Chen J, Alcaine SD, Jackson AA, Rotello VM, Nugen SR. Development of Engineered Bacteriophages for Escherichia coli Detection and High-Throughput Antibiotic Resistance Determination. ACS Sens. 2017 Apr 28; 2(4):484-489. PMID: 28723178.
      View in: PubMed
    9. Wang D, Chen J, Nugen SR. Electrochemical Detection of Escherichia coli from Aqueous Samples Using Engineered Phages. Anal Chem. 2017 Feb 07; 89(3):1650-1657. PMID: 28208254.
      View in: PubMed
    10. Dai M, Chen J, Goddard JM, Nugen SR. Facile hierarchical assembly of gold particle decorated conductive polymer nanofibers for electrochemical sensing. Nanotechnology. 2017 Feb 10; 28(6):06LT01. PMID: 28044995.
      View in: PubMed
    11. Chen J, Andler SM, Goddard JM, Nugen SR, Rotello VM. Integrating recognition elements with nanomaterials for bacteria sensing. Chem Soc Rev. 2016 Dec 12. PMID: 27942636.
      View in: PubMed
    12. Koo CK, Senecal K, Senecal A, Nugen SR. Dehydration of bacteriophages in electrospun nanofibers: effect of excipients in polymeric solutions. Nanotechnology. 2016 Dec 2; 27(48):485102. PMID: 27819799.
      View in: PubMed
    13. Wang D, Wang Z, He F, Kinchla AJ, Nugen SR. Enzymatic Digestion for Improved Bacteria Separation from Leafy Green Vegetables. J Food Prot. 2016 Aug; 79(8):1378-86. PMID: 27497125.
      View in: PubMed
    14. Jackson AA, Hinkley TC, Talbert JN, Nugen SR, Sela DA. Genetic optimization of a bacteriophage-delivered alkaline phosphatase reporter to detect Escherichia coli. Analyst. 2016 Oct 7; 141(19):5543-8. PMID: 27412402.
      View in: PubMed
    15. Huang K, Chen J, Nugen SR, Goddard JM. Hybrid Antifouling and Antimicrobial Coatings Prepared by Electroless Co-Deposition of Fluoropolymer and Cationic Silica Nanoparticles on Stainless Steel: Efficacy against Listeria monocytogenes. ACS Appl Mater Interfaces. 2016 Jun 29; 8(25):15926-36. PMID: 27268033.
      View in: PubMed
    16. Talbert JN, Alcaine SD, Nugen SR. Engineering bacteriophage for a pragmatic low-resource setting bacterial diagnostic platform. Bioengineered. 2016 Apr; 7(3):132-6. PMID: 27246532.
      View in: PubMed
    17. Chen J, Pang S, He L, Nugen SR. Highly sensitive and selective detection of nitrite ions using Fe3O4@SiO2/Au magnetic nanoparticles by surface-enhanced Raman spectroscopy. Biosens Bioelectron. 2016 Nov 15; 85:726-33. PMID: 27262558.
      View in: PubMed
    18. Wang Z, Wang D, Kinchla AJ, Sela DA, Nugen SR. Rapid screening of waterborne pathogens using phage-mediated separation coupled with real-time PCR detection. Anal Bioanal Chem. 2016 Jun; 408(15):4169-78. PMID: 27071764.
      View in: PubMed
    19. Alcaine SD, Law K, Ho S, Kinchla AJ, Sela DA, Nugen SR. Bioengineering bacteriophages to enhance the sensitivity of phage amplification-based paper fluidic detection of bacteria. Biosens Bioelectron. 2016 Aug 15; 82:14-9. PMID: 27031186.
      View in: PubMed
    20. Chen J, Jackson AA, Rotello VM, Nugen SR. Colorimetric Detection of Escherichia coli Based on the Enzyme-Induced Metallization of Gold Nanorods. Small. 2016 May; 12(18):2469-75. PMID: 26997252.
      View in: PubMed
    21. Wang P, Pang S, Chen J, McLandsborough L, Nugen SR, Fan M, He L. Label-free mapping of single bacterial cells using surface-enhanced Raman spectroscopy. Analyst. 2016 Feb 21; 141(4):1356-62. PMID: 26750611.
      View in: PubMed
    22. Wang Z, Wang D, Chen J, Sela DA, Nugen SR. Development of a novel bacteriophage based biomagnetic separation method as an aid for sensitive detection of viable Escherichia coli. Analyst. 2016 Feb 07; 141(3):1009-16. PMID: 26689710.
      View in: PubMed
    23. Alcaine SD, Molla L, Nugen SR, Kruse H. Results of a pilot antibiotic resistance survey of Albanian poultry farms. J Glob Antimicrob Resist. 2016 Mar; 4:60-4. PMID: 27436396.
      View in: PubMed
    24. Alcaine SD, Pacitto D, Sela DA, Nugen SR. Phage & phosphatase: a novel phage-based probe for rapid, multi-platform detection of bacteria. Analyst. 2015 Nov 21; 140(22):7629-36. PMID: 26421320.
      View in: PubMed
    25. Chen J, Duncan B, Wang Z, Wang LS, Rotello VM, Nugen SR. Bacteriophage-based nanoprobes for rapid bacteria separation. Nanoscale. 2015 Oct 21; 7(39):16230-6. PMID: 26315848.
      View in: PubMed
    26. Chen J, Li Y, Huang K, Wang P, He L, Carter KR, Nugen SR. Nanoimprinted Patterned Pillar Substrates for Surface-Enhanced Raman Scattering Applications. ACS Appl Mater Interfaces. 2015 Oct 7; 7(39):22106-13. PMID: 26402032.
      View in: PubMed
    27. Chen J, Alcaine SD, Jiang Z, Rotello VM, Nugen SR. Detection of Escherichia coli in drinking water using T7 bacteriophage-conjugated magnetic probe. Anal Chem. 2015 Sep 1; 87(17):8977-84. PMID: 26172120.
      View in: PubMed
    28. Alcaine SD, Tilton L, Serrano MA, Wang M, Vachet RW, Nugen SR. Phage-protease-peptide: a novel trifecta enabling multiplex detection of viable bacterial pathogens. Appl Microbiol Biotechnol. 2015 Oct; 99(19):8177-85. PMID: 26245682.
      View in: PubMed
    29. Chen J, Jiang Z, Ackerman JD, Yazdani M, Hou S, Nugen SR, Rotello VM. Electrochemical nanoparticle-enzyme sensors for screening bacterial contamination in drinking water. Analyst. 2015 Aug 7; 140(15):4991-6. PMID: 26042607.
      View in: PubMed
    30. Chen J, Zhou Y, Wang D, He F, Rotello VM, Carter KR, Watkins JJ, Nugen SR. UV-nanoimprint lithography as a tool to develop flexible microfluidic devices for electrochemical detection. Lab Chip. 2015 Jul 21; 15(14):3086-94. PMID: 26095586.
      View in: PubMed
    31. He F, Grimes J, Alcaine SD, Nugen SR. A hybrid paper and microfluidic chip with electrowetting valves and colorimetric detection. Analyst. 2014 Jun 21; 139(12):3002-8. PMID: 24719901.
      View in: PubMed
    32. Dai M, Senecal A, Nugen SR. Electrospun water-soluble polymer nanofibers for the dehydration and storage of sensitive reagents. Nanotechnology. 2014 Jun 6; 25(22):225101. PMID: 24815520.
      View in: PubMed
    33. Talbert JN, He F, Seto K, Nugen SR, Goddard JM. Modification of glucose oxidase for the development of biocatalytic solvent inks. Enzyme Microb Technol. 2014 Feb 5; 55:21-5. PMID: 24411441.
      View in: PubMed
    34. Wang Y, Nugen SR. Development of fluorescent nanoparticle-labeled lateral flow assay for the detection of nucleic acids. Biomed Microdevices. 2013 Oct; 15(5):751-8. PMID: 23525961.
      View in: PubMed
    35. Koo CK, He F, Nugen SR. An inkjet-printed electrowetting valve for paper-fluidic sensors. Analyst. 2013 Sep 7; 138(17):4998-5004. PMID: 23828822.
      View in: PubMed
    36. Dai M, Jin S, Nugen SR. Water-soluble electrospun nanofibers as a method for on-chip reagent storage. Biosensors (Basel). 2012; 2(4):388-95. PMID: 25586029.
      View in: PubMed
    37. Wang Y, Fill C, Nugen SR. Development of chemiluminescent lateral flow assay for the detection of nucleic acids. Biosensors (Basel). 2012; 2(1):32-42. PMID: 25585630.
      View in: PubMed
    38. Goddard JM, Mandal S, Nugen SR, Baeumner AJ, Erickson D. Biopatterning for label-free detection. Colloids Surf B Biointerfaces. 2010 Mar 1; 76(1):375-80. PMID: 19939644.
      View in: PubMed
    39. Kumanan V, Nugen SR, Baeumner AJ, Chang YF. A biosensor assay for the detection of Mycobacterium avium subsp. paratuberculosis in fecal samples. J Vet Sci. 2009 Mar; 10(1):35-42. PMID: 19255522.
      View in: PubMed
    40. Nugen SR, Asiello PJ, Connelly JT, Baeumner AJ. PMMA biosensor for nucleic acids with integrated mixer and electrochemical detection. Biosens Bioelectron. 2009 Apr 15; 24(8):2428-33. PMID: 19168346.
      View in: PubMed
    41. Nugen SR, Baeumner AJ. Trends and opportunities in food pathogen detection. Anal Bioanal Chem. 2008 May; 391(2):451-4. PMID: 18347781.
      View in: PubMed
    42. Connelly JT, Nugen SR, Borejsza-Wysocki W, Durst RA, Montagna RA, Baeumner AJ. Human pathogenic Cryptosporidium species bioanalytical detection method with single oocyst detection capability. Anal Bioanal Chem. 2008 May; 391(2):487-95. PMID: 18311563.
      View in: PubMed
    43. Nugen SR, Leonard B, Baeumner AJ. Application of a unique server-based oligonucleotide probe selection tool toward a novel biosensor for the detection of Streptococcus pyogenes. Biosens Bioelectron. 2007 May 15; 22(11):2442-8. PMID: 17011180.
      View in: PubMed
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