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Last Name
Institution

William F Flynn Jr. MD

TitleAdjunct Assistant Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentSurgery
Address22 Mill Street, Suite 301
Arlington VA 02476
Phone781-643-6313
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentSurgery


    Collapse Biography 
    Collapse education and training
    Boston College, Chestnut Hill, MA, United StatesBALiberal Arts
    Yale University School of Medicine, New Haven, CT, United StatesMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Gowthaman U, Chen JS, Zhang B, Flynn WF, Lu Y, Song W, Joseph J, Gertie JA, Xu L, Collet MA, Grassmann JDS, Simoneau T, Chiang D, Berin MC, Craft JE, Weinstein JS, Williams A, Eisenbarth SC. Identification of a T follicular helper cell subset that drives anaphylactic IgE. Science. 2019 Aug 01. PMID: 31371561.
      View in: PubMed
    2. Elyada E, Bolisetty M, Laise P, Flynn WF, Courtois ET, Burkhart RA, Teinor JA, Belleau P, Biffi G, Lucito MS, Sivajothi S, Armstrong TD, Engle DD, Yu KH, Hao Y, Wolfgang CL, Park Y, Preall J, Jaffee EM, Califano A, Robson P, Tuveson DA. Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts. Cancer Discov. 2019 Jun 13. PMID: 31197017.
      View in: PubMed
    3. Sharma M, Srivastava A, Fairfield HE, Bergstrom D, Flynn WF, Braun RE. Identification of EOMES-expressing spermatogonial stem cells and their regulation by PLZF. Elife. 2019 May 31; 8. PMID: 31149899.
      View in: PubMed
    4. Xia J, Flynn W, Gallicchio E, Uplinger K, Armstrong JD, Forli S, Olson AJ, Levy RM. Massive-Scale Binding Free Energy Simulations of HIV Integrase Complexes Using Asynchronous Replica Exchange Framework Implemented on the IBM WCG Distributed Network. J Chem Inf Model. 2019 Feb 13. PMID: 30758197.
      View in: PubMed
    5. Xia J, Flynn W, Levy RM. Improving Prediction Accuracy of Binding Free Energies and Poses of HIV Integrase Complexes Using the Binding Energy Distribution Analysis Method with Flattening Potentials. J Chem Inf Model. 2018 Jul 23; 58(7):1356-1371. PMID: 29927237.
      View in: PubMed
    6. Haldane A, Flynn WF, He P, Levy RM. Coevolutionary Landscape of Kinase Family Proteins: Sequence Probabilities and Functional Motifs. Biophys J. 2018 Jan 09; 114(1):21-31. PMID: 29320688.
      View in: PubMed
    7. Flynn WF, Haldane A, Torbett BE, Levy RM. Inference of Epistatic Effects Leading to Entrenchment and Drug Resistance in HIV-1 Protease. Mol Biol Evol. 2017 Mar 20. PMID: 28369521.
      View in: PubMed
    8. Pal RK, Haider K, Kaur D, Flynn W, Xia J, Levy RM, Taran T, Wickstrom L, Kurtzman T, Gallicchio E. Erratum to: A combined treatment of hydration and dynamical effects for the modeling of host-guest binding thermodynamics: the SAMPL5 blinded challenge. J Comput Aided Mol Des. 2017 Jan; 31(1):45. PMID: 27815770.
      View in: PubMed
    9. Levy RM, Haldane A, Flynn WF. Potts Hamiltonian models of protein co-variation, free energy landscapes, and evolutionary fitness. Curr Opin Struct Biol. 2016 Nov 18; 43:55-62. PMID: 27870991.
      View in: PubMed
    10. Pal RK, Haider K, Kaur D, Flynn W, Xia J, Levy RM, Taran T, Wickstrom L, Kurtzman T, Gallicchio E. A combined treatment of hydration and dynamical effects for the modeling of host-guest binding thermodynamics: the SAMPL5 blinded challenge. J Comput Aided Mol Des. 2016 Sep 30. PMID: 27696239.
      View in: PubMed
    11. Deng N, Flynn WF, Xia J, Vijayan RS, Zhang B, He P, Mentes A, Gallicchio E, Levy RM. Large scale free energy calculations for blind predictions of protein-ligand binding: the D3R Grand Challenge 2015. J Comput Aided Mol Des. 2016 Sep; 30(9):743-751. PMID: 27562018.
      View in: PubMed
    12. Haldane A, Flynn WF, He P, Vijayan RS, Levy RM. Structural propensities of kinase family proteins from a Potts model of residue co-variation. Protein Sci. 2016 Aug; 25(8):1378-84. PMID: 27241634.
      View in: PubMed
    13. Gallicchio E, Xia J, Flynn WF, Zhang B, Samlalsingh S, Mentes A, Levy RM. Asynchronous Replica Exchange Software for Grid and Heterogeneous Computing. Comput Phys Commun. 2015 Nov; 196:236-246. PMID: 27103749.
      View in: PubMed
    14. Xia J, Flynn WF, Gallicchio E, Zhang BW, He P, Tan Z, Levy RM. Large-scale asynchronous and distributed multidimensional replica exchange molecular simulations and efficiency analysis. J Comput Chem. 2015 Sep 5; 36(23):1772-85. PMID: 26149645.
      View in: PubMed
    15. Flynn WF, Chang MW, Tan Z, Oliveira G, Yuan J, Okulicz JF, Torbett BE, Levy RM. Deep sequencing of protease inhibitor resistant HIV patient isolates reveals patterns of correlated mutations in Gag and protease. PLoS Comput Biol. 2015 Apr; 11(4):e1004249. PMID: 25894830.
      View in: PubMed
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