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Connection

Phillip Zamore to Humans

This is a "connection" page, showing publications Phillip Zamore has written about Humans.
Connection Strength

0.577
  1. Wu PH, Zamore PD. Defining the functions of PIWI-interacting RNAs. Nat Rev Mol Cell Biol. 2021 04; 22(4):239-240.
    View in: PubMed
    Score: 0.029
  2. ?zata DM, Yu T, Mou H, Gainetdinov I, Colpan C, Cecchini K, Kaymaz Y, Wu PH, Fan K, Kucukural A, Weng Z, Zamore PD. Evolutionarily conserved pachytene piRNA loci are highly divergent among modern humans. Nat Ecol Evol. 2020 01; 4(1):156-168.
    View in: PubMed
    Score: 0.026
  3. Li C, Zamore PD. RNA Interference and Small RNA Analysis. Cold Spring Harb Protoc. 2019 04 01; 2019(4).
    View in: PubMed
    Score: 0.025
  4. Ozata DM, Gainetdinov I, Zoch A, O'Carroll D, Zamore PD. PIWI-interacting RNAs: small RNAs with big functions. Nat Rev Genet. 2019 02; 20(2):89-108.
    View in: PubMed
    Score: 0.025
  5. Zamore PD. Molecular biology: Rhino gives voice to silent chromatin. Nature. 2017 09 06; 549(7670):38-39.
    View in: PubMed
    Score: 0.022
  6. Zamore P. Startups on the menu: Alnylam. Nat Biotechnol. 2014 Sep; 32(9):866.
    View in: PubMed
    Score: 0.018
  7. Han BW, Zamore PD. piRNAs. Curr Biol. 2014 Aug 18; 24(16):R730-3.
    View in: PubMed
    Score: 0.018
  8. Fukunaga R, Zamore PD. A universal small molecule, inorganic phosphate, restricts the substrate specificity of Dicer-2 in small RNA biogenesis. Cell Cycle. 2014; 13(11):1671-6.
    View in: PubMed
    Score: 0.018
  9. Ameres SL, Zamore PD. Diversifying microRNA sequence and function. Nat Rev Mol Cell Biol. 2013 Aug; 14(8):475-88.
    View in: PubMed
    Score: 0.017
  10. Fukunaga R, Han BW, Hung JH, Xu J, Weng Z, Zamore PD. Dicer partner proteins tune the length of mature miRNAs in flies and mammals. Cell. 2012 Oct 26; 151(3):533-46.
    View in: PubMed
    Score: 0.016
  11. Broderick JA, Salomon WE, Ryder SP, Aronin N, Zamore PD. Argonaute protein identity and pairing geometry determine cooperativity in mammalian RNA silencing. RNA. 2011 Oct; 17(10):1858-69.
    View in: PubMed
    Score: 0.015
  12. Cenik ES, Zamore PD. Argonaute proteins. Curr Biol. 2011 Jun 21; 21(12):R446-9.
    View in: PubMed
    Score: 0.015
  13. Broderick JA, Zamore PD. MicroRNA therapeutics. Gene Ther. 2011 Dec; 18(12):1104-10.
    View in: PubMed
    Score: 0.014
  14. Ameres SL, Horwich MD, Hung JH, Xu J, Ghildiyal M, Weng Z, Zamore PD. Target RNA-directed trimming and tailing of small silencing RNAs. Science. 2010 Jun 18; 328(5985):1534-9.
    View in: PubMed
    Score: 0.014
  15. Pfister EL, Zamore PD. Huntington's disease: silencing a brutal killer. Exp Neurol. 2009 Dec; 220(2):226-9.
    View in: PubMed
    Score: 0.013
  16. Izaurralde E, Zamore PD. Nucleus and gene expression. Curr Opin Cell Biol. 2009 Jun; 21(3):331-4.
    View in: PubMed
    Score: 0.013
  17. Barringhaus KG, Zamore PD. MicroRNAs: regulating a change of heart. Circulation. 2009 Apr 28; 119(16):2217-24.
    View in: PubMed
    Score: 0.012
  18. Horwich MD, Zamore PD. Design and delivery of antisense oligonucleotides to block microRNA function in cultured Drosophila and human cells. Nat Protoc. 2008; 3(10):1537-49.
    View in: PubMed
    Score: 0.011
  19. Du T, Zamore PD. Beginning to understand microRNA function. Cell Res. 2007 Aug; 17(8):661-3.
    View in: PubMed
    Score: 0.011
  20. Zamore PD. RNA silencing: genomic defence with a slice of pi. Nature. 2007 Apr 19; 446(7138):864-5.
    View in: PubMed
    Score: 0.011
  21. Schwarz DS, Ding H, Kennington L, Moore JT, Schelter J, Burchard J, Linsley PS, Aronin N, Xu Z, Zamore PD. Designing siRNA that distinguish between genes that differ by a single nucleotide. PLoS Genet. 2006 Sep 08; 2(9):e140.
    View in: PubMed
    Score: 0.010
  22. Seitz H, Zamore PD. Rethinking the microprocessor. Cell. 2006 Jun 02; 125(5):827-9.
    View in: PubMed
    Score: 0.010
  23. Matranga C, Tomari Y, Shin C, Bartel DP, Zamore PD. Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell. 2005 Nov 18; 123(4):607-20.
    View in: PubMed
    Score: 0.010
  24. Du T, Zamore PD. microPrimer: the biogenesis and function of microRNA. Development. 2005 Nov; 132(21):4645-52.
    View in: PubMed
    Score: 0.010
  25. Zamore PD, Haley B. Ribo-gnome: the big world of small RNAs. Science. 2005 Sep 02; 309(5740):1519-24.
    View in: PubMed
    Score: 0.010
  26. Tomari Y, Zamore PD. Perspective: machines for RNAi. Genes Dev. 2005 Mar 01; 19(5):517-29.
    View in: PubMed
    Score: 0.009
  27. Tomari Y, Zamore PD. MicroRNA biogenesis: drosha can't cut it without a partner. Curr Biol. 2005 Jan 26; 15(2):R61-4.
    View in: PubMed
    Score: 0.009
  28. Hutv?gner G, Simard MJ, Mello CC, Zamore PD. Sequence-specific inhibition of small RNA function. PLoS Biol. 2004 Apr; 2(4):E98.
    View in: PubMed
    Score: 0.009
  29. Zamore PD, Aronin N. siRNAs knock down hepatitis. Nat Med. 2003 Mar; 9(3):266-7.
    View in: PubMed
    Score: 0.008
  30. Iyer S, Mir A, Vega-Badillo J, Roscoe BP, Ibraheim R, Zhu LJ, Lee J, Liu P, Luk K, Mintzer E, Guo D, Soares de Brito J, Emerson CP, Zamore PD, Sontheimer EJ, Wolfe SA. Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors. CRISPR J. 2022 10; 5(5):685-701.
    View in: PubMed
    Score: 0.008
  31. Schwarz DS, Hutv?gner G, Haley B, Zamore PD. Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Mol Cell. 2002 Sep; 10(3):537-48.
    View in: PubMed
    Score: 0.008
  32. Hutv?gner G, Zamore PD. A microRNA in a multiple-turnover RNAi enzyme complex. Science. 2002 Sep 20; 297(5589):2056-60.
    View in: PubMed
    Score: 0.008
  33. Zamore PD. Ancient pathways programmed by small RNAs. Science. 2002 May 17; 296(5571):1265-9.
    View in: PubMed
    Score: 0.008
  34. Schwarz DS, Zamore PD. Why do miRNAs live in the miRNP? Genes Dev. 2002 May 01; 16(9):1025-31.
    View in: PubMed
    Score: 0.008
  35. Chen Z, Devi G, Arif A, Zamore PD, Sontheimer EJ, Watts JK. Tetrazine-Ligated CRISPR sgRNAs for Efficient Genome Editing. ACS Chem Biol. 2022 May 20; 17(5):1045-1050.
    View in: PubMed
    Score: 0.008
  36. Zamore PD. RNA interference: listening to the sound of silence. Nat Struct Biol. 2001 Sep; 8(9):746-50.
    View in: PubMed
    Score: 0.007
  37. Hutv?gner G, McLachlan J, Pasquinelli AE, B?lint E, Tuschl T, Zamore PD. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science. 2001 Aug 03; 293(5531):834-8.
    View in: PubMed
    Score: 0.007
  38. Xie J, Tai PWL, Brown A, Gong S, Zhu S, Wang Y, Li C, Colpan C, Su Q, He R, Ma H, Li J, Ye H, Ko J, Zamore PD, Gao G. Effective and Accurate Gene Silencing by a Recombinant AAV-Compatible MicroRNA Scaffold. Mol Ther. 2020 02 05; 28(2):422-430.
    View in: PubMed
    Score: 0.007
  39. Hassler MR, Turanov AA, Alterman JF, Haraszti RA, Coles AH, Osborn MF, Echeverria D, Nikan M, Salomon WE, Roux L, Godinho BMDC, Davis SM, Morrissey DV, Zamore PD, Karumanchi SA, Moore MJ, Aronin N, Khvorova A. Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo. Nucleic Acids Res. 2018 03 16; 46(5):2185-2196.
    View in: PubMed
    Score: 0.006
  40. Zamore PD, Williamson JR, Lehmann R. The Pumilio protein binds RNA through a conserved domain that defines a new class of RNA-binding proteins. RNA. 1997 Dec; 3(12):1421-33.
    View in: PubMed
    Score: 0.006
  41. Ouimet M, Koster S, Sakowski E, Ramkhelawon B, van Solingen C, Oldebeken S, Karunakaran D, Portal-Celhay C, Sheedy FJ, Ray TD, Cecchini K, Zamore PD, Rayner KJ, Marcel YL, Philips JA, Moore KJ. Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism. Nat Immunol. 2016 06; 17(6):677-86.
    View in: PubMed
    Score: 0.005
  42. Chou MT, Han BW, Hsiao CP, Zamore PD, Weng Z, Hung JH. Tailor: a computational framework for detecting non-templated tailing of small silencing RNAs. Nucleic Acids Res. 2015 Sep 30; 43(17):e109.
    View in: PubMed
    Score: 0.005
  43. Roy CK, Olson S, Graveley BR, Zamore PD, Moore MJ. Assessing long-distance RNA sequence connectivity via RNA-templated DNA-DNA ligation. Elife. 2015 Apr 13; 4.
    View in: PubMed
    Score: 0.005
  44. Babcock GJ, Iyer S, Smith HL, Wang Y, Rowley K, Ambrosino DM, Zamore PD, Pierce BG, Molrine DC, Weng Z. High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody. PLoS One. 2014; 9(6):e100325.
    View in: PubMed
    Score: 0.004
  45. Chung RT, Gordon FD, Curry MP, Schiano TD, Emre S, Corey K, Markmann JF, Hertl M, Pomposelli JJ, Pomfret EA, Florman S, Schilsky M, Broering TJ, Finberg RW, Szabo G, Zamore PD, Khettry U, Babcock GJ, Ambrosino DM, Leav B, Leney M, Smith HL, Molrine DC. Human monoclonal antibody MBL-HCV1 delays HCV viral rebound following liver transplantation: a randomized controlled study. Am J Transplant. 2013 Apr; 13(4):1047-1054.
    View in: PubMed
    Score: 0.004
  46. Liu W, Chaurette J, Pfister EL, Kennington LA, Chase KO, Bullock J, Vonsattel JP, Faull RL, Macdonald D, DiFiglia M, Zamore PD, Aronin N. Increased Steady-State Mutant Huntingtin mRNA in Huntington's Disease Brain. J Huntingtons Dis. 2013; 2(4):491-500.
    View in: PubMed
    Score: 0.004
  47. Zamore PD, Patton JG, Green MR. Cloning and domain structure of the mammalian splicing factor U2AF. Nature. 1992 Feb 13; 355(6361):609-14.
    View in: PubMed
    Score: 0.004
  48. Mueller C, Tang Q, Gruntman A, Blomenkamp K, Teckman J, Song L, Zamore PD, Flotte TR. Sustained miRNA-mediated knockdown of mutant AAT with simultaneous augmentation of wild-type AAT has minimal effect on global liver miRNA profiles. Mol Ther. 2012 03; 20(3):590-600.
    View in: PubMed
    Score: 0.004
  49. Zamore PD, Green MR. Biochemical characterization of U2 snRNP auxiliary factor: an essential pre-mRNA splicing factor with a novel intranuclear distribution. EMBO J. 1991 Jan; 10(1):207-14.
    View in: PubMed
    Score: 0.004
  50. Carone BR, Fauquier L, Habib N, Shea JM, Hart CE, Li R, Bock C, Li C, Gu H, Zamore PD, Meissner A, Weng Z, Hofmann HA, Friedman N, Rando OJ. Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals. Cell. 2010 Dec 23; 143(7):1084-96.
    View in: PubMed
    Score: 0.004
  51. Xie J, Xie Q, Zhang H, Ameres SL, Hung JH, Su Q, He R, Mu X, Seher Ahmed S, Park S, Kato H, Li C, Mueller C, Mello CC, Weng Z, Flotte TR, Zamore PD, Gao G. MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression. Mol Ther. 2011 Mar; 19(3):526-35.
    View in: PubMed
    Score: 0.004
  52. Zamore PD, Green MR. Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor. Proc Natl Acad Sci U S A. 1989 Dec; 86(23):9243-7.
    View in: PubMed
    Score: 0.003
  53. Pfister EL, Kennington L, Straubhaar J, Wagh S, Liu W, DiFiglia M, Landwehrmeyer B, Vonsattel JP, Zamore PD, Aronin N. Five siRNAs targeting three SNPs may provide therapy for three-quarters of Huntington's disease patients. Curr Biol. 2009 May 12; 19(9):774-8.
    View in: PubMed
    Score: 0.003
  54. Liu W, Kennington LA, Rosas HD, Hersch S, Cha JH, Zamore PD, Aronin N. Linking SNPs to CAG repeat length in Huntington's disease patients. Nat Methods. 2008 Nov; 5(11):951-3.
    View in: PubMed
    Score: 0.003
  55. Rossi J, Zamore P, Kay MA. Wandering eye for RNAi. Nat Med. 2008 Jun; 14(6):611.
    View in: PubMed
    Score: 0.003
  56. DiFiglia M, Sena-Esteves M, Chase K, Sapp E, Pfister E, Sass M, Yoder J, Reeves P, Pandey RK, Rajeev KG, Manoharan M, Sah DW, Zamore PD, Aronin N. Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits. Proc Natl Acad Sci U S A. 2007 Oct 23; 104(43):17204-9.
    View in: PubMed
    Score: 0.003
  57. Ding H, Schwarz DS, Keene A, Affar el B, Fenton L, Xia X, Shi Y, Zamore PD, Xu Z. Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis. Aging Cell. 2003 08; 2(4):209-17.
    View in: PubMed
    Score: 0.002
  58. Wang X, McLachlan J, Zamore PD, Hall TM. Modular recognition of RNA by a human pumilio-homology domain. Cell. 2002 Aug 23; 110(4):501-12.
    View in: PubMed
    Score: 0.002
  59. Wang X, Zamore PD, Hall TM. Crystal structure of a Pumilio homology domain. Mol Cell. 2001 Apr; 7(4):855-65.
    View in: PubMed
    Score: 0.002
  60. Lee CG, Zamore PD, Green MR, Hurwitz J. RNA annealing activity is intrinsically associated with U2AF. J Biol Chem. 1993 Jun 25; 268(18):13472-8.
    View in: PubMed
    Score: 0.001
  61. Valc?rcel J, Singh R, Zamore PD, Green MR. The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA. Nature. 1993 Mar 11; 362(6416):171-5.
    View in: PubMed
    Score: 0.001
  62. Zhang M, Zamore PD, Carmo-Fonseca M, Lamond AI, Green MR. Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit. Proc Natl Acad Sci U S A. 1992 Sep 15; 89(18):8769-73.
    View in: PubMed
    Score: 0.001
  63. Carmo-Fonseca M, Tollervey D, Pepperkok R, Barabino SM, Merdes A, Brunner C, Zamore PD, Green MR, Hurt E, Lamond AI. Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery. EMBO J. 1991 Jan; 10(1):195-206.
    View in: PubMed
    Score: 0.001
  64. Ruskin B, Zamore PD, Green MR. A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly. Cell. 1988 Jan 29; 52(2):207-19.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.