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Armando E Fraire MD

TitleProfessor Emeritus
InstitutionUMass Chan Medical School
AddressUMass Chan Medical School
One Innovation Drive Biotech Three
Worcester MA 01605
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DivisionAnatomic Pathology

    Collapse Biography 
    Collapse education and training
    Colegio Civil, Monterrey, NL, MexicoBSScience
    Universidad Autonoma de Nuevo Leon, San Nicolas de los Garza, NL, MexicoMD

    Collapse Overview 
    Collapse overview

    Academic Background:

    M.D.University of Nuevo Leon, Monterrey, Mexico

    Pathology Residency, Baylor College of Medicine, Houston, TX

    Research Interests:Dr. Armondo Fraire

    My research interest is primarily the study of neoplastic and non-neoplastic lung disease.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kamionek M, Ahmadi Moghaddam P, Sakhdari A, Kovach AE, Welch M, Meng X, Dresser K, Tomaszewicz K, Cosar EF, Mark EJ, Fraire AE, Hutchinson L. Mutually exclusive extracellular signal-regulated kinase pathway mutations are present in different stages of multi-focal pulmonary Langerhans cell histiocytosis supporting clonal nature of the disease. Histopathology. 2016 Sep; 69(3):499-509. PMID: 26915300.
      Citations: 17     Fields:    Translation:HumansCells
    2. Fraire AE. Brief Updates in Lung Pathology. Arch Pathol Lab Med. 2015 Aug; 139(8):973. PMID: 26230590.
      Citations:    Fields:    Translation:Humans
    3. Virk RK, Fraire AE. Interstitial Lung Diseases That Are Difficult to Classify: A Review of Bronchiolocentric Interstitial Lung Disease. Arch Pathol Lab Med. 2015 Aug; 139(8):984-8. PMID: 26230593.
      Citations: 3     Fields:    Translation:Humans
    4. Boundy KE, Fraire AE, Oliveira PJ. A patient with progressive dyspnea and multiple foci of airspace consolidation. Chest. 2014 Jan; 145(1):167-172. PMID: 24394829.
      Citations: 2     Fields:    Translation:Humans
    5. Libraty DH, Bocelli L, Fraire A. Herpes simplex virus bronchiolitis in a cannabis user. IDCases. 2014; 1(1):2-4. PMID: 26912481.
    6. Fraire AE. Five top stories in anatomic pathology: stories from the faculty at UMass Medical School and UMass Memorial Medical Center, Worcester, Massachusetts. Arch Pathol Lab Med. 2013 Jul; 137(7):886. PMID: 23808459.
      Citations:    Fields:    Translation:Humans
    7. Cornejo KM, Shi M, Akalin A, Uy K, Cagle PT, Fraire AE. Pulmonary papillary adenoma: a case report and review of the literature. J Bronchology Interv Pulmonol. 2013 Jan; 20(1):52-7. PMID: 23328145.
      Citations: 6     Fields:    Translation:Humans
    8. Husain AN, Colby T, Ordonez N, Krausz T, Attanoos R, Beasley MB, Borczuk AC, Butnor K, Cagle PT, Chirieac LR, Churg A, Dacic S, Fraire A, Galateau-Salle F, Gibbs A, Gown A, Hammar S, Litzky L, Marchevsky AM, Nicholson AG, Roggli V, Travis WD, Wick M. Guidelines for pathologic diagnosis of malignant mesothelioma: 2012 update of the consensus statement from the International Mesothelioma Interest Group. Arch Pathol Lab Med. 2013 May; 137(5):647-67. PMID: 22929121.
      Citations: 135     Fields:    Translation:Humans
    9. Solky AC, Laver NM, Williams J, Fraire A. Prototheca wickerhamii infection of a corneal graft. Cornea. 2011 Oct; 30(10):1173-5. PMID: 21795977.
      Citations: 3     Fields:    Translation:HumansAnimals
    10. Hariri LP, Mino-Kenudson M, Shea B, Digumarthy S, Onozato M, Yagi Y, Fraire AE, Matsubara O, Mark EJ. Distinct histopathology of acute onset or abrupt exacerbation of hypersensitivity pneumonitis. Hum Pathol. 2012 May; 43(5):660-8. PMID: 21855112.
      Citations: 14     Fields:    Translation:Humans
    11. Shi M, Fraire AE, Chu P, Cornejo K, Woda BA, Dresser K, Rock KL, Jiang Z. Oncofetal protein IMP3, a new diagnostic biomarker to distinguish malignant mesothelioma from reactive mesothelial proliferation. Am J Surg Pathol. 2011 Jun; 35(6):878-82. PMID: 21566519.
      Citations: 13     Fields:    Translation:Humans
    12. Owens CL, Fraire AE. Combined carcinoid tumor and squamous cell carcinoma of lung: expanding the spectrum of combined tumors of lung. Int J Surg Pathol. 2011 Apr; 19(2):273-5. PMID: 21427100.
      Citations: 6     Fields:    Translation:Humans
    13. Murawski MR, McGinnes LW, Finberg RW, Kurt-Jones EA, Massare MJ, Smith G, Heaton PM, Fraire AE, Morrison TG. Newcastle disease virus-like particles containing respiratory syncytial virus G protein induced protection in BALB/c mice, with no evidence of immunopathology. J Virol. 2010 Jan; 84(2):1110-23. PMID: 19889768.
      Citations: 81     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    14. Ressmeyer AR, Bai Y, Delmotte P, Uy KF, Thistlethwaite P, Fraire A, Sato O, Ikebe M, Sanderson MJ. Human airway contraction and formoterol-induced relaxation is determined by Ca2+ oscillations and Ca2+ sensitivity. Am J Respir Cell Mol Biol. 2010 Aug; 43(2):179-91. PMID: 19767449.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    15. Zota V, Angelis SM, Fraire AE, McNamee C, Kielbasa S, Libraty DH. Lessons from Mycobacterium avium complex-associated pneumonitis: a case report. J Med Case Rep. 2008 May 13; 2:152. PMID: 18477401.
      Citations: 1     Fields:    
    16. Fraire AE. Hypersensitivity pneumonitis: a commentary. Arch Pathol Lab Med. 2008 Feb; 132(2):192-4. PMID: 18251574.
      Citations: 2     Fields:    Translation:Humans
    17. Li C, Zota V, Woda BA, Rock KL, Fraire AE, Jiang Z, Lu D, Xu B, Dresser K, Lutman CV, Fischer AH. Expression of a novel oncofetal mRNA-binding protein IMP3 in endometrial carcinomas: diagnostic significance and clinicopathologic correlations. Mod Pathol. 2007 Dec; 20(12):1263-8. PMID: 17885673.
      Citations: 19     Fields:    Translation:Humans
    18. Fraire A. Histopathology of pneumothorax: potential diagnostic pitfalls. Arch Pathol Lab Med. 2007 Jun; 131(6):848-9. PMID: 17550309.
      Citations:    Fields:    Translation:HumansCells
    19. Li C, Rock KL, Woda BA, Jiang Z, Fraire AE, Dresser K. IMP3 is a novel biomarker for adenocarcinoma in situ of the uterine cervix: an immunohistochemical study in comparison with p16(INK4a) expression. Mod Pathol. 2007 Feb; 20(2):242-7. PMID: 17192788.
      Citations: 37     Fields:    Translation:Humans
    20. Irwin RS, Ownbey R, Cagle PT, Baker S, Fraire AE. Interpreting the histopathology of chronic cough: a prospective, controlled, comparative study. Chest. 2006 Aug; 130(2):362-70. PMID: 16899833.
      Citations: 32     Fields:    Translation:Humans
    21. Choi DJ, Wallace EC, Fraire AE, Baiyee D. Best cases from the AFIP: intrarenal teratoma. Radiographics. 2005 Mar-Apr; 25(2):481-5. PMID: 15798064.
      Citations: 8     Fields:    Translation:Humans
    22. Ko E, Mortimer E, Fraire AE. Extraarticular synovial chondromatosis: review of epidemiology, imaging studies, microscopy and pathogenesis, with a report of an additional case in a child. Int J Surg Pathol. 2004 Jul; 12(3):273-80. PMID: 15306942.
      Citations: 8     Fields:    Translation:Humans
    23. Nikitin AY, Alcaraz A, Anver MR, Bronson RT, Cardiff RD, Dixon D, Fraire AE, Gabrielson EW, Gunning WT, Haines DC, Kaufman MH, Linnoila RI, Maronpot RR, Rabson AS, Reddick RL, Rehm S, Rozengurt N, Schuller HM, Shmidt EN, Travis WD, Ward JM, Jacks T. Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium. Cancer Res. 2004 Apr 01; 64(7):2307-16. PMID: 15059877.
      Citations: 168     Fields:    Translation:HumansAnimals
    24. Cai YC, Roggli V, Mark E, Cagle PT, Fraire AE. Transforming growth factor alpha and epidermal growth factor receptor in reactive and malignant mesothelial proliferations. Arch Pathol Lab Med. 2004 Jan; 128(1):68-70. PMID: 14692808.
      Citations: 3     Fields:    Translation:Humans
    25. Ullmann R, Bongiovanni M, Halbwedl I, Fraire AE, Cagle PT, Mori M, Papotti M, Popper HH. Is high-grade adenomatous hyperplasia an early bronchioloalveolar adenocarcinoma? J Pathol. 2003 Nov; 201(3):371-6. PMID: 14595748.
      Citations: 1     Fields:    Translation:HumansCells
    26. Chen HD, Fraire AE, Joris I, Welsh RM, Selin LK. Specific history of heterologous virus infections determines anti-viral immunity and immunopathology in the lung. Am J Pathol. 2003 Oct; 163(4):1341-55. PMID: 14507643.
      Citations: 77     Fields:    Translation:AnimalsCells
    27. Cappelluti E, Fraire AE, Schaefer OP. A case of "hot tub lung" due to Mycobacterium avium complex in an immunocompetent host. Arch Intern Med. 2003 Apr 14; 163(7):845-8. PMID: 12695276.
      Citations: 9     Fields:    Translation:HumansCells
    28. Ullmann R, Petzmann S, Klemen H, Fraire AE, Hasleton P, Popper HH. The position of pulmonary carcinoids within the spectrum of neuroendocrine tumors of the lung and other tissues. Genes Chromosomes Cancer. 2002 May; 34(1):78-85. PMID: 11921285.
      Citations: 13     Fields:    Translation:Humans
    29. Mori M, Rao SK, Popper HH, Cagle PT, Fraire AE. Atypical adenomatous hyperplasia of the lung: a probable forerunner in the development of adenocarcinoma of the lung. Mod Pathol. 2001 Feb; 14(2):72-84. PMID: 11235908.
      Citations: 33     Fields:    Translation:HumansAnimals
    30. Irwin RS, Madison JM, Fraire AE. The cough reflex and its relation to gastroesophageal reflux. Am J Med. 2000 Mar 06; 108 Suppl 4a:73S-78S. PMID: 10718456.
      Citations: 7     Fields:    Translation:Humans
    31. Boag AH, Colby TV, Fraire AE, Kuhn C, Roggli VL, Travis WD, Vallyathan V. The pathology of interstitial lung disease in nylon flock workers. Am J Surg Pathol. 1999 Dec; 23(12):1539-45. PMID: 10584708.
      Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
    32. Simkin PH, Ramirez LA, Zweizig SL, Afonso SA, Fraire AE, Khan A, Dunn AD, Dunn JT, Braverman LE. Monomorphic teratoma of the ovary: a rare cause of triiodothyronine toxicosis. Thyroid. 1999 Sep; 9(9):949-54. PMID: 10524575.
      Citations: 4     Fields:    Translation:Humans
    33. Jiang Z, Woda BA, Savas L, Fraire AE. Expression of ICAM-1, VCAM-1, and LFA-1 in adenocarcinoma of the lung with observations on the expression of these adhesion molecules in non-neoplastic lung tissue. Mod Pathol. 1998 Dec; 11(12):1189-92. PMID: 9872650.
      Citations: 5     Fields:    Translation:Humans
    34. Curley FJ, Johal JS, Burke ME, Fraire AE. Transbronchial lung biopsy: can specimen quality be predicted at the time of biopsy? Chest. 1998 Apr; 113(4):1037-41. PMID: 9554644.
      Citations: 12     Fields:    Translation:Humans
    35. Dickson EW, Heard SO, Chu B, Fraire A, Brueggemann AB, Doern GV. Partial liquid ventilation with perfluorocarbon in the treatment of rats with lethal pneumococcal pneumonia. Anesthesiology. 1998 Jan; 88(1):218-23. PMID: 9447875.
      Citations: 2     Fields:    Translation:Animals
    36. Osmanski JP, Fraire AE, Schaefer OP. Necrotizing tracheobronchitis with progressive airflow obstruction associated with paraneoplastic pemphigus. Chest. 1997 Dec; 112(6):1704-7. PMID: 9404781.
      Citations:    Fields:    Translation:Humans
    37. Mori M, Kohli A, Baker SP, Savas L, Fraire AE. Laminin and cathepsin B as prognostic factors in stage I non-small cell lung cancer: are they useful? Mod Pathol. 1997 Jun; 10(6):572-7. PMID: 9195574.
      Citations: 1     Fields:    Translation:Humans
    38. Fraire AE, Greenberg SD, Spjut HJ, Dodson RF, Williams G, Lach-Pasko E, Roggli VL. Effect of erionite on the pleural mesothelium of the Fischer 344 rat. Chest. 1997 May; 111(5):1375-80. PMID: 9149597.
      Citations: 5     Fields:    Translation:Animals
    39. Sterner DJ, Mori M, Roggli VL, Fraire AE. Prevalence of pulmonary atypical alveolar cell hyperplasia in an autopsy population: a study of 100 cases. Mod Pathol. 1997 May; 10(5):469-73. PMID: 9160312.
      Citations: 6     Fields:    Translation:Humans
    40. Cagle PT, Fraire AE, Greenberg SD, Cox A, Brown RW. Potential utility of p53 immunopositivity in differentiation of adenocarcinomas from reactive epithelial atypias of the lung. Hum Pathol. 1996 Nov; 27(11):1198-203. PMID: 8912831.
      Citations:    Fields:    Translation:Humans
    41. Fraire AE, Kemp B, Greenberg SD, Kim HS, Estrada R, McBride RA. Calcofluor white stain for the detection of Pneumocystis carinii in transbronchial lung biopsy specimens: a study of 68 cases. Mod Pathol. 1996 Aug; 9(8):861-4. PMID: 8871929.
      Citations: 2     Fields:    Translation:HumansAnimals
    42. Rao SK, Krishna M, Woda BA, Savas L, Fraire AE. Immunohistochemical detection of bcl-2 protein in adenocarcinoma and non-neoplastic cellular compartments of the lung. Mod Pathol. 1996 May; 9(5):555-9. PMID: 8733771.
      Citations: 3     Fields:    Translation:Humans
    43. Conway EJ, Hudnall SD, Lazarides A, Bahler A, Fraire AE, Cagle PT. Absence of evidence for an etiologic role for Epstein-Barr virus in neoplasms of the lung and pleura. Mod Pathol. 1996 May; 9(5):491-5. PMID: 8733763.
      Citations: 3     Fields:    Translation:HumansCells
    44. Mello CJ, Veronikis I, Fraire AE, Aronin N, Irwin RS, Braverman LE. Metastatic papillary thyroid carcinoma to lung diagnosed by bronchoalveolar lavage. J Clin Endocrinol Metab. 1996 Jan; 81(1):406-10. PMID: 8550785.
      Citations:    Fields:    Translation:Humans
    45. Savarese DM, Rohrer MJ, Pezzella AT, Davidoff A, Fraire AE, Menon M. Successful management of intracardiac extension of tumor thrombus in a patient with advanced nonseminomatous germ cell testicular cancer. Urology. 1995 Dec; 46(6):883-7. PMID: 7502438.
      Citations: 11     Fields:    Translation:HumansCells
    46. Shaker KG, Umali CB, Fraire AE. Langerhans' cell histiocytosis of the lung in association with mediastinal lymphadenopathy. Pathol Int. 1995 Oct; 45(10):762-6. PMID: 8563938.
      Citations: 1     Fields:    Translation:Humans
    47. Rao SK, Fraire AE. Alveolar cell hyperplasia in association with adenocarcinoma of lung. Mod Pathol. 1995 Feb; 8(2):165-9. PMID: 7777478.
      Citations: 4     Fields:    Translation:Humans
    48. Fraire AE, Greenberg SD, Spjut HJ, Roggli VL, Dodson RF, Cartwright J, Williams G, Baker S. Effect of fibrous glass on rat pleural mesothelium. Histopathologic observations. Am J Respir Crit Care Med. 1994 Aug; 150(2):521-7. PMID: 8049840.
      Citations: 1     Fields:    Translation:Animals
    49. Ha TV, Kleinman PK, Fraire A, Spevak MR, Nimkin K, Cohen IT, Hirsh M, Walton R. MR imaging of benign fatty tumors in children: report of four cases and review of the literature. Skeletal Radiol. 1994 Jul; 23(5):361-7. PMID: 7939836.
      Citations: 9     Fields:    Translation:Humans
    50. Bailey ME, Fraire AE, Greenberg SD, Barnard J, Cagle PT. Pulmonary histopathology in cocaine abusers. Hum Pathol. 1994 Feb; 25(2):203-7. PMID: 8119721.
      Citations: 11     Fields:    Translation:Humans
    51. Rose PG, Fraire AE. Multiple primary gynecologic neoplasms in a young HIV-positive patient. J Surg Oncol. 1993 Aug; 53(4):269-72. PMID: 8393503.
      Citations: 2     Fields:    Translation:Humans
    52. Shahab I, Fraire AE, Greenberg SD, Johnson EH, Langston C, Roggli VL. Morphometric quantitation of tumor necrosis in stage 1 non-small cell carcinoma of lung: prognostic implications. Mod Pathol. 1992 Sep; 5(5):521-4. PMID: 1344816.
      Citations: 3     Fields:    Translation:Humans
    53. Cagle PT, Langston C, Fraire AE, Roggli VL, Greenberg SD. Absence of correlation between nuclear morphometry and survival in stage I non-small cell lung carcinoma. Cancer. 1992 May 15; 69(10):2454-7. PMID: 1314690.
      Citations: 1     Fields:    Translation:HumansCells
    54. Fraire AE, Johnson EH, Yesner R, Zhang XB, Spjut HJ, Greenberg SD. Prognostic significance of histopathologic subtype and stage in small cell lung cancer. Hum Pathol. 1992 May; 23(5):520-8. PMID: 1314777.
      Citations: 15     Fields:    Translation:Humans
    55. Mountain CF, Greenberg SD, Fraire AE. Tumor stage in non-small cell carcinoma of the lung. Chest. 1991 May; 99(5):1258-60. PMID: 1850345.
      Citations: 3     Fields:    Translation:Humans
    56. Scroggs MW, Roggli VL, Fraire AE, Sanfilippo F. Eosinophilic intracytoplasmic globules in pulmonary adenocarcinomas: a histochemical, immunohistochemical, and ultrastructural study of six cases. Hum Pathol. 1989 Sep; 20(9):845-9. PMID: 2476374.
      Citations: 2     Fields:    Translation:HumansCells
    57. Fraire AE, Cooper S, Greenberg SD, Buffler P, Langston C. Mesothelioma of childhood. Cancer. 1988 Aug 15; 62(4):838-47. PMID: 3293765.
      Citations: 15     Fields:    Translation:Humans
    58. Elson CE, Roggli VL, Vollmer RT, Greenberg SD, Fraire AE, Spjut HJ, Yesner R. Prognostic indicators for survival in stage I carcinoma of the lung: a histologic study of 47 surgically resected cases. Mod Pathol. 1988 Jul; 1(4):288-91. PMID: 2853362.
      Citations: 1     Fields:    Translation:Humans
    59. Fraire AE, Roggli VL, Vollmer RT, Greenberg SD, McGavran MH, Spjut HJ, Yesner R. Lung cancer heterogeneity. Prognostic implications. Cancer. 1987 Aug 01; 60(3):370-5. PMID: 3594372.
      Citations: 5     Fields:    Translation:Humans
    60. Greenberg SD, Fraire AE, Kinner BM, Johnson EH. Tumor cell type versus staging in the prognosis of carcinoma of the lung. Pathol Annu. 1987; 22 Pt 2:387-405. PMID: 2825102.
      Citations: 3     Fields:    Translation:Humans
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