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Richard T Ellison III MD

TitleProfessor
InstitutionUniversity of Massachusetts Medical School
DepartmentMedicine
AddressUniversity of Massachusetts Medical School
55 Lake Avenue North
Worcester MA 01655
Phone508-856-3158
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentMedicine
    DivisionInfectious Diseases And Immunology

    InstitutionUMMS - School of Medicine
    DepartmentMicrobiology and Physiological Systems

    InstitutionUMMS - Graduate School of Biomedical Sciences
    DepartmentClinical Population Health Research

    InstitutionUMMS - Graduate School of Biomedical Sciences
    DepartmentMolecular Genetics and Microbiology


    Collapse Biography 
    Collapse education and training
    University of Virginia, Charlottesville, VA, United StatesBAArts
    Hahemann Medical College, Philadelphia, PA, United StatesMD

    Collapse Overview 
    Collapse overview

    Background

    Education:

    • B.A., University of Virginia, 1973
    • M.D., Hahnemann Medical College, 1977

    Post-Graduate Training:

    • Internal Medicine Residency, Rhode Island Hospital, Providence, RI, 1977-80
    • Chief Medical Resident, Veterans Administration Medical Center, Providence, RI, 1980-81
    • Infectious Disease Fellowship, University of Colorado, Denver, CO, 1981-83

    Board Certification:

    • National Board of Medical Examiners, 1978
    • Diplomate, American Board of Internal Medicine, 1980
    • Diplomate, American Board of Internal Medicine (Infectious Diseases), 1984

    Honors and Awards:

    • Fellow, American College of Physicians
    • Western Society of Clinical Investigation
    • Fellow, Infectious Disease Society of America
    • President, Massachusetts Infectious Disease Society, 1998-2001
    • Fellow, Society for Healthcare Epidemiology of America

     

    Other Activities:

    • Deputy Editor, Journal Watch for Infectious Diseases

    Research/Clinical Interests

    Photo: Richard T Ellison IIIResearch Interests: Dr. Ellison's clinical research interests focus on the broad areas of identification and treatment of nosocomial infections, infections in the ICU setting, sepsis, and clinical care of patients with HIV disease. Recent work has been focused on the use of medical information system databases in identifying both infections and other adverse events in the inpatient setting; as well as novel approaches to preventing nosocomial infections. His laboratory research interests have been into the nature of innate antimicrobial host defense systems towards bacterial pathogens. This has involved studies of the complement system and antimicrobial proteins including lactoferrin, lysozyme, and natural antimicrobial peptides. More recent work has involved studies of a new class of antimicrobial agents active towards Gram-positive bacterial pathogens and bacterial antimicrobial resistance mechanisms.

    Clinical Interests: Dr. Ellison provides subspecialty consultative care in the field of Infectious Diseases, as well as primary medical care to individuals with HIV disease.

     




    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ward DV, Hoss AG, Kolde R, van Aggelen HC, Loving J, Smith SA, Mack DA, Kathirvel R, Halperin JA, Buell DJ, Wong BE, Ashworth JL, Fortunato-Habib MM, Xu L, Barton BA, Lazar P, Carmona JJ, Mathew J, Salgo IS, Gross BD, Ellison RT. Integration of genomic and clinical data augments surveillance of healthcare-acquired infections. Infect Control Hosp Epidemiol. 2019 Apr 23; 1-7. PMID: 31012399.
      View in: PubMed
    2. Gandra S, Barysauskas CM, Mack DA, Barton B, Finberg R, Ellison RT. Impact of elimination of contact precautions on noninfectious adverse events among MRSA and VRE patients. Infect Control Hosp Epidemiol. 2018 Aug 31; 1. PMID: 30168402.
      View in: PubMed
    3. Poowanawittayakom N, Dutta A, Stock S, Touray S, Ellison RT, Levitz SM. Reemergence of Intravenous Drug Use as Risk Factor for Candidemia, Massachusetts, USA. Emerg Infect Dis. 2018 Apr; 24(4). PMID: 29553923.
      View in: PubMed
    4. Kotkowski K, Ellison RT, Barysauskas C, Barton B, Allison J, Mack D, Finberg RW, Reznek M. Association of hospital contact precaution policies with emergency department admission time. J Hosp Infect. 2017 Jul; 96(3):244-249. PMID: 28454768.
      View in: PubMed
    5. Civitarese AM, Ruggieri E, Walz JM, Mack DA, Heard SO, Mitchell M, Lilly CM, Landry KE, Ellison RT. A ten-year review of total hospital onset intensive care unit bloodstream infections at an Academic Medical Center. Chest. 2017 Feb 16. PMID: 28215789.
      View in: PubMed
    6. Proulx MK, Ellison RT, Goguen JD. Reply to Gelfand and Cleveland. J Infect Dis. 2016 May 15; 213(10):1671-2. PMID: 26962234.
      View in: PubMed
    7. Uyeki TM, Erickson BR, Brown S, McElroy AK, Cannon D, Gibbons A, Sealy T, Kainulainen MH, Schuh AJ, Kraft CS, Mehta AK, Lyon GM, Varkey JB, Ribner BS, Ellison RT, Carmody E, Nau GJ, Spiropoulou C, Nichol ST, Ströher U. Ebola Virus Persistence in Semen of Male Survivors. Clin Infect Dis. 2016 Jun 15; 62(12):1552-5. PMID: 27045122.
      View in: PubMed
    8. Chancellor JR, Padmanabhan SP, Greenough TC, Sacra R, Ellison RT, Madoff LC, Droms RJ, Hinkle DM, Asdourian GK, Finberg RW, Stroher U, Uyeki TM, Cerón OM. Uveitis and Systemic Inflammatory Markers in Convalescent Phase of Ebola Virus Disease. Emerg Infect Dis. 2016 Feb; 22(2):295-7. PMID: 26812218.
      View in: PubMed
    9. Bradbury SL, Reznek M, Sullivan S, Adamo P, Mack D, Ellison RT. Electronic control device prongs: a growing cause of bloodborne pathogen exposure? Am J Infect Control. 2015 Dec 01; 43(12):1373-4. PMID: 26654240.
      View in: PubMed
    10. Proulx MK, Palace SG, Gandra S, Torres B, Weir S, Stiles T, Ellison RT, Goguen JD. Reversion From Methicillin Susceptibility to Methicillin Resistance in Staphylococcus aureus During Treatment of Bacteremia. J Infect Dis. 2016 Mar 15; 213(6):1041-8. PMID: 26503983.
      View in: PubMed
    11. Martin H, Hermos C, Barysauskas CM, Bradbury S, Sullivan S, Ellison RT. Accidental Needlestick Exposures linked to the Administration of Local Anesthesia by Healthcare Workers. Infect Control Hosp Epidemiol. 2015 Dec; 36(12):1487-8. PMID: 26449423.
      View in: PubMed
    12. Ellison RT, Barysauskas CM, Rundensteiner EA, Wang D, Barton B. A Prospective Controlled Trial of an Electronic Hand Hygiene Reminder System. Open Forum Infect Dis. 2015 Dec; 2(4):ofv121. PMID: 26430698.
      View in: PubMed
    13. Walz JM, Ellison RT, Mack DA, Flaherty HM, McIlwaine JK, Whyte KG, Landry KE, Baker SP, Heard SO. The bundle "plus": the effect of a multidisciplinary team approach to eradicate central line-associated bloodstream infections. Anesth Analg. 2015 Apr; 120(4):868-76. PMID: 24149581.
      View in: PubMed
    14. Lilly CM, Landry KE, Sood RN, Ellison RT, Bagley PH, Baker SP, Cody S, Irwin RS. The authors reply. Crit Care Med. 2015 Feb; 43(2):e61-2. PMID: 25599510.
      View in: PubMed
    15. Gandra S, Barysauskas CM, Mack DA, Barton B, Finberg R, Ellison RT. Impact of contact precautions on falls, pressure ulcers and transmission of MRSA and VRE in hospitalized patients. J Hosp Infect. 2014 Nov; 88(3):170-6. PMID: 25441487.
      View in: PubMed
    16. Lilly CM, Landry KE, Sood RN, Dunnington CH, Ellison RT, Bagley PH, Baker SP, Cody S, Irwin RS. Prevalence and test characteristics of national health safety network ventilator-associated events. Crit Care Med. 2014 Sep; 42(9):2019-28. PMID: 24810522.
      View in: PubMed
    17. Tsyrkunou AV, Ellison RT, Akalin A, Wiederhold N, Sutton DA, Lindner J, Fan H, Levitz SM, Zivna I. Multifocal Rhizopus microsporus lung infection following brush clearing. Med Mycol Case Rep. 2014 Oct; 6:14-7. PMID: 25379391.
      View in: PubMed
    18. Bradbury SL, Mack D, Crofts T, Ellison RT. Potential bloodborne pathogen exposure from occult mattress damage. Am J Infect Control. 2014 Apr; 42(4):421-2. PMID: 24559597.
      View in: PubMed
    19. Lilly CM, Ellison RT. Quality measures for critically ill patients: where does ventilator-associated condition fit in? Chest. 2013 Nov; 144(5):1429-30. PMID: 24189848.
      View in: PubMed
    20. Gandra S, Ellison RT. Modern trends in infection control practices in intensive care units. J Intensive Care Med. 2014 Nov-Dec; 29(6):311-26. PMID: 23753240.
      View in: PubMed
    21. Manuell ME, Co MD, Ellison RT. Pandemic influenza: implications for preparation and delivery of critical care services. J Intensive Care Med. 2011 Nov-Dec; 26(6):347-67. PMID: 21220275.
      View in: PubMed
    22. Wang D, Rundensteiner E, Ellison RT III, Wang H. Active Complex Event Processing infrastructure: Monitoring and reacting to event streams. Data Engineering Workshops (ICDEW), IEEE. 2011; 249-254.
    23. Yu C, Baker S, Morse LJ, Gardiner J, Meehan M, Esposito A, Roberto R, Ellison RT. Clinical and laboratory findings in individuals with acute norovirus disease. Arch Intern Med. 2007 Sep 24; 167(17):1903-5. PMID: 17893314.
      View in: PubMed
    24. Zivna I, Bergin D, Casavant J, Fontecchio S, Nelson S, Kelley A, Mathis S, Melvin Z, Erlichman R, Ellison RT. Impact of Bordetella pertussis exposures on a Massachusetts tertiary care medical system. Infect Control Hosp Epidemiol. 2007 Jun; 28(6):708-12. PMID: 17520545.
      View in: PubMed
    25. Ellison RT. Review: probiotics are effective for prevention of antibiotic-associated diarrhea and treatment of Clostridium difficile disease. ACP J Club. 2006 Sep-Oct; 145(2):46. PMID: 16944866.
      View in: PubMed
    26. Daly JS, Giehl TJ, Brown NC, Zhi C, Wright GE, Ellison RT. In vitro antimicrobial activities of novel anilinouracils which selectively inhibit DNA polymerase III of gram-positive bacteria. Antimicrob Agents Chemother. 2000 Aug; 44(8):2217-21. PMID: 10898708.
      View in: PubMed
    27. Sharkey ME, Teo I, Greenough T, Sharova N, Luzuriaga K, Sullivan JL, Bucy RP, Kostrikis LG, Haase A, Veryard C, Davaro RE, Cheeseman SH, Daly JS, Bova C, Ellison RT, Mady B, Lai KK, Moyle G, Nelson M, Gazzard B, Shaunak S, Stevenson M. Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy. Nat Med. 2000 Jan; 6(1):76-81. PMID: 10613828.
      View in: PubMed
    28. Ellison RT. Steroid therapy for late septic shock. Crit Care Med. 1999 Jul; 27(7):1402. PMID: 10446849.
      View in: PubMed
    29. Riester KA, Peduzzi P, Holford TR, Ellison RT, Donta ST. Statistical evaluation of the role of Helicobacter pylori in stress gastritis: applications of splines and bootstrapping to the logistic model. J Clin Epidemiol. 1997 Nov; 50(11):1273-9. PMID: 9393383.
      View in: PubMed
    30. Ellison RT, Perez-Perez G, Welsh CH, Blaser MJ, Riester KA, Cross AS, Donta ST, Peduzzi P. Risk factors for upper gastrointestinal bleeding in intensive care unit patients: role of helicobacter pylori. Federal Hyperimmune Immunoglobulin Therapy Study Group. Crit Care Med. 1996 Dec; 24(12):1974-81. PMID: 8968264.
      View in: PubMed
    31. Donta ST, Peduzzi P, Cross AS, Sadoff J, Haakenson C, Cryz SJ, Kauffman C, Bradley S, Gafford G, Elliston D, Beam TR, John JF, Ribner B, Cantey R, Welsh CH, Ellison RT, Young EJ, Hamill RJ, Leaf H, Schein RM, Mulligan M, Johnson C, Abrutyn E, Griffiss JM, Slagle D, et al. Immunoprophylaxis against klebsiella and pseudomonas aeruginosa infections. The Federal Hyperimmune Immunoglobulin Trial Study Group. J Infect Dis. 1996 Sep; 174(3):537-43. PMID: 8769611.
      View in: PubMed
    32. Davaro RE, Cheeseman SH, Keroack MA, Ellison RT. The significance of isolated antibody to hepatitis B core antigen seropositivity in patients infected with human immunodeficiency virus. Clin Infect Dis. 1996 Jul; 23(1):189-90. PMID: 8816158.
      View in: PubMed
    33. Cheeseman SH, Davaro RE, Ellison RT. Hepatitis B vaccination and plasma HIV-1 RNA. N Engl J Med. 1996 May 9; 334(19):1272. PMID: 8606735.
      View in: PubMed
    34. Bessesen MT, Miller LA, Cohn DL, Bartlett S, Ellison RT. Administration of pyrimethamine/sulfadoxine for prevention of Pneumocystis carinii pneumonia in patients with AIDS. Clin Infect Dis. 1995 Mar; 20(3):730-1. PMID: 7756514.
      View in: PubMed
    35. Ellison RT. The effects of lactoferrin on gram-negative bacteria. Adv Exp Med Biol. 1994; 357:71-90. PMID: 7762448.
      View in: PubMed
    36. Yamauchi K, Tomita M, Giehl TJ, Ellison RT. Antibacterial activity of lactoferrin and a pepsin-derived lactoferrin peptide fragment. Infect Immun. 1993 Feb; 61(2):719-28. PMID: 8423097.
      View in: PubMed
    37. MacKenzie TD, Ellison RT, Mostow SR. Sunlight and cholera. Lancet. 1992 Aug 8; 340(8815):367. PMID: 1353822.
      View in: PubMed
    38. Marr JJ, Baum KF, Chapman AD, Douglas JM, Ellison RT, Marman GW, Perlman D, Riley HE, Sintek CD, Woltemath DA. Development of an antimicrobial formulary for a university teaching hospital system. Am J Hosp Pharm. 1992 Jun; 49(6):1481-4. PMID: 1529996.
      View in: PubMed
    39. Ellison RT, Giehl TJ. Killing of gram-negative bacteria by lactoferrin and lysozyme. J Clin Invest. 1991 Oct; 88(4):1080-91. PMID: 1918365.
      View in: PubMed
    40. Pei ZH, Ellison RT, Blaser MJ. Identification, purification, and characterization of major antigenic proteins of Campylobacter jejuni. J Biol Chem. 1991 Sep 5; 266(25):16363-9. PMID: 1885571.
      View in: PubMed
    41. Holdcroft CJ, Ellison RT. Trimethoprim-sulfamethoxazole reaction simulating Pneumocystis carinii pneumonia. AIDS. 1991 Aug; 5(8):1029. PMID: 1777163.
      View in: PubMed
    42. Ehni WF, Reller LB, Ellison RT. Bacteremia in granulocytopenic patients in a tertiary-care general hospital. Rev Infect Dis. 1991 Jul-Aug; 13(4):613-9. PMID: 1925279.
      View in: PubMed
    43. Bessesen MT, Luo QA, Rotbart HA, Blaser MJ, Ellison RT. Detection of Listeria monocytogenes by using the polymerase chain reaction. Appl Environ Microbiol. 1990 Sep; 56(9):2930-2. PMID: 2125817.
      View in: PubMed
    44. Ellison RT, LaForce FM, Giehl TJ, Boose DS, Dunn BE. Lactoferrin and transferrin damage of the gram-negative outer membrane is modulated by Ca2+ and Mg2+. J Gen Microbiol. 1990 Jul; 136(7):1437-46. PMID: 2230724.
      View in: PubMed
    45. Ellison RT, Luo Q, Reller LB. Enhancement of the activity of cefotaxime by iron-binding proteins. J Antimicrob Chemother. 1990 Mar; 25(3):479-81. PMID: 2338426.
      View in: PubMed
    46. Ellison RT, Horsburgh CR, Curd J. Complement levels in patients with hepatic dysfunction. Dig Dis Sci. 1990 Feb; 35(2):231-5. PMID: 2302981.
      View in: PubMed
    47. Cover TL, Dunn BE, Ellison RT, Blaser MJ. Vibrio cholerae wound infection acquired in Colorado. J Infect Dis. 1989 Dec; 160(6):1083. PMID: 2584756.
      View in: PubMed
    48. Ellison RT, Giehl TJ, LaForce FM. Damage of the outer membrane of enteric gram-negative bacteria by lactoferrin and transferrin. Infect Immun. 1988 Nov; 56(11):2774-81. PMID: 3169987.
      View in: PubMed
    49. Pei Z, Ellison RT, Lewis RV, Blaser MJ. Purification and characterization of a family of high molecular weight surface-array proteins from Campylobacter fetus. J Biol Chem. 1988 May 5; 263(13):6416-20. PMID: 3360785.
      View in: PubMed
    50. Ellison RT, Giehl TJ. Pulmonary secretions accelerate the metabolic rate of Escherichia coli. Microb Pathog. 1988 Jan; 4(1):15-20. PMID: 3059136.
      View in: PubMed
    51. Ellison RT. Colorado tick fever or ehrlichiosis. JAMA. 1987 Oct 2; 258(13):1731-2. PMID: 3041059.
      View in: PubMed
    52. Ehni WF, Ellison RT. Spontaneous Candida albicans meningitis in a patient with the acquired immune deficiency syndrome. Am J Med. 1987 Oct; 83(4):806-7. PMID: 3674071.
      View in: PubMed
    53. Ellison RT, Curd JG, Kohler PF, Reller LB, Judson FN. Underlying complement deficiency in patients with disseminated gonococcal infection. Sex Transm Dis. 1987 Oct-Dec; 14(4):201-4. PMID: 2830678.
      View in: PubMed
    54. Ellison RT, McGregor JA. Recurrent postcoital lower-extremity streptococcal erythroderma in women. Streptococcal-sex syndrome. JAMA. 1987 Jun 19; 257(23):3260-2. PMID: 2953912.
      View in: PubMed
    55. LaForce FM, Boose DS, Ellison RT. Effect of aerosolized Escherichia coli and Staphylococcus aureus on iron and iron-binding proteins in lung lavage fluid. J Infect Dis. 1986 Dec; 154(6):959-65. PMID: 3537153.
      View in: PubMed
    56. Ellison RT, Mason SR, Kohler PF, Curd JG, Reller LB. Meningococcemia and acquired complement deficiency. Association in patients with hepatic failure. Arch Intern Med. 1986 Aug; 146(8):1539-40. PMID: 3729633.
      View in: PubMed
    57. Ellison RT, Reller LB. Differentiating pyogenic arthritis from spontaneous hemarthrosis in patients with hemophilia. West J Med. 1986 Jan; 144(1):42-5. PMID: 3953068.
      View in: PubMed
    58. Cooper ER, Ellison RT, Smith GS, Blaser MJ, Reller LB, Paisley JW. Rifampin-resistant meningococcal disease in a contact patient given prophylactic rifampin. J Pediatr. 1986 Jan; 108(1):93-6. PMID: 3080574.
      View in: PubMed
    59. Ellison RT, Boose D, LaForce FM. Isolation of an antibacterial peptide from human lung lavage fluid. J Infect Dis. 1985 Jun; 151(6):1123-9. PMID: 3923130.
      View in: PubMed
    60. Blaser MJ, Ellison RT. Rapid nighttime evacuation of a veterans hospital. J Emerg Med. 1985; 3(5):387-94. PMID: 3835193.
      View in: PubMed
    61. Ellison RT, Mostow SR. Pyogenic meningitis manifesting during therapy for Aeromonas hydrophila sepsis. Arch Intern Med. 1984 Oct; 144(10):2078-9. PMID: 6091581.
      View in: PubMed
    62. Ellison RT, Judson FN, Peterson LC, Cohn DL, Ehret JM. Oral rifampin and trimethoprim/sulfamethoxazole therapy in asymptomatic carriers of methicillin-resistant Staphylococcus aureus infections. West J Med. 1984 May; 140(5):735-40. PMID: 6610253.
      View in: PubMed
    63. Ellison RT, Kohler PF, Curd JG, Judson FN, Reller LB. Prevalence of congenital or acquired complement deficiency in patients with sporadic meningocococcal disease. N Engl J Med. 1983 Apr 21; 308(16):913-6. PMID: 6835295.
      View in: PubMed
    64. Ellison RT, Corrao WM, Fox MJ, Braman SS. Spontaneous mediastinal hemorrhage in patients on chronic hemodialysis. Ann Intern Med. 1981 Dec; 95(6):704-6. PMID: 7305150.
      View in: PubMed
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