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Dale Greiner to Humans

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This is a "connection" page, showing publications Dale Greiner has written about Humans.
Dale Greiner
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0.965
Humans
  1. Shultz LD, Goodwin N, Ishikawa F, Hosur V, Lyons BL, Greiner DL. Subcapsular transplantation of tissue in the kidney. Cold Spring Harb Protoc. 2014 Jul 01; 2014(7):737-40.
    View in: PubMed
    Score: 0.018
  2. Shultz LD, Goodwin N, Ishikawa F, Hosur V, Lyons BL, Greiner DL. Human cancer growth and therapy in immunodeficient mouse models. Cold Spring Harb Protoc. 2014 Jul 01; 2014(7):694-708.
    View in: PubMed
    Score: 0.018
  3. Brehm MA, Shultz LD, Luban J, Greiner DL. Overcoming current limitations in humanized mouse research. J Infect Dis. 2013 Nov; 208 Suppl 2:S125-30.
    View in: PubMed
    Score: 0.017
  4. Shultz LD, Brehm MA, Garcia-Martinez JV, Greiner DL. Humanized mice for immune system investigation: progress, promise and challenges. Nat Rev Immunol. 2012 Nov; 12(11):786-98.
    View in: PubMed
    Score: 0.016
  5. Brehm MA, Powers AC, Shultz LD, Greiner DL. Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice. Cold Spring Harb Perspect Med. 2012 May; 2(5):a007757.
    View in: PubMed
    Score: 0.015
  6. Liu G, Dou S, Akalin A, Rusckowski M, Streeter PR, Shultz LD, Greiner DL. Pretargeting vs. direct targeting of human betalox5 islet cells subcutaneously implanted in mice using an anti-human islet cell antibody. Nucl Med Biol. 2012 Jul; 39(5):645-51.
    View in: PubMed
    Score: 0.015
  7. Brehm MA, Racki WJ, Leif J, Burzenski L, Hosur V, Wetmore A, Gott B, Herlihy M, Ignotz R, Dunn R, Shultz LD, Greiner DL. Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2r? null mice is enhanced by transgenic expression of membrane-bound human SCF. Blood. 2012 Mar 22; 119(12):2778-88.
    View in: PubMed
    Score: 0.015
  8. Shultz LD, Brehm MA, Bavari S, Greiner DL. Humanized mice as a preclinical tool for infectious disease and biomedical research. Ann N Y Acad Sci. 2011 Dec; 1245:50-4.
    View in: PubMed
    Score: 0.015
  9. Greiner DL, Brehm MA, Hosur V, Harlan DM, Powers AC, Shultz LD. Humanized mice for the study of type 1 and type 2 diabetes. Ann N Y Acad Sci. 2011 Dec; 1245:55-8.
    View in: PubMed
    Score: 0.015
  10. Liu G, Dou S, Cheng D, Leif J, Rusckowski M, Streeter PR, Shultz LD, Hnatowich DJ, Greiner DL. Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model. Mol Pharm. 2011 Jun 06; 8(3):767-73.
    View in: PubMed
    Score: 0.014
  11. Brehm MA, Shultz LD, Greiner DL. Humanized mouse models to study human diseases. Curr Opin Endocrinol Diabetes Obes. 2010 Apr; 17(2):120-5.
    View in: PubMed
    Score: 0.013
  12. Racki WJ, Covassin L, Brehm M, Pino S, Ignotz R, Dunn R, Laning J, Graves SK, Rossini AA, Shultz LD, Greiner DL. NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection. Transplantation. 2010 Mar 15; 89(5):527-36.
    View in: PubMed
    Score: 0.013
  13. Brehm MA, Cuthbert A, Yang C, Miller DM, DiIorio P, Laning J, Burzenski L, Gott B, Foreman O, Kavirayani A, Herlihy M, Rossini AA, Shultz LD, Greiner DL. Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation. Clin Immunol. 2010 Apr; 135(1):84-98.
    View in: PubMed
    Score: 0.013
  14. King MA, Covassin L, Brehm MA, Racki W, Pearson T, Leif J, Laning J, Fodor W, Foreman O, Burzenski L, Chase TH, Gott B, Rossini AA, Bortell R, Shultz LD, Greiner DL. Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex. Clin Exp Immunol. 2009 Jul; 157(1):104-18.
    View in: PubMed
    Score: 0.013
  15. King M, Pearson T, Rossini AA, Shultz LD, Greiner DL. Humanized mice for the study of type 1 diabetes and beta cell function. Ann N Y Acad Sci. 2008 Dec; 1150:46-53.
    View in: PubMed
    Score: 0.012
  16. Pearson T, Shultz LD, Miller D, King M, Laning J, Fodor W, Cuthbert A, Burzenski L, Gott B, Lyons B, Foreman O, Rossini AA, Greiner DL. Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment. Clin Exp Immunol. 2008 Nov; 154(2):270-84.
    View in: PubMed
    Score: 0.012
  17. Giassi LJ, Pearson T, Shultz LD, Laning J, Biber K, Kraus M, Woda BA, Schmidt MR, Woodland RT, Rossini AA, Greiner DL. Expanded CD34+ human umbilical cord blood cells generate multiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice. Exp Biol Med (Maywood). 2008 Aug; 233(8):997-1012.
    View in: PubMed
    Score: 0.012
  18. Pearson T, Shultz LD, Lief J, Burzenski L, Gott B, Chase T, Foreman O, Rossini AA, Bottino R, Trucco M, Greiner DL. A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function. Diabetologia. 2008 Aug; 51(8):1449-56.
    View in: PubMed
    Score: 0.012
  19. Miller DM, Rossini AA, Greiner DL. Role of innate immunity in transplantation tolerance. Crit Rev Immunol. 2008; 28(5):403-39.
    View in: PubMed
    Score: 0.011
  20. King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, Atkinson MA, Wasserfall C, Herold KC, Woodland RT, Schmidt MR, Woda BA, Thompson MJ, Rossini AA, Greiner DL. A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene. Clin Immunol. 2008 Mar; 126(3):303-14.
    View in: PubMed
    Score: 0.011
  21. King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, Atkinson M, Wasserfall C, Herold K, Mordes JP, Rossini AA, Greiner DL. Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity. Ann N Y Acad Sci. 2007 Apr; 1103:90-3.
    View in: PubMed
    Score: 0.011
  22. Rossini AA, Greiner DL. Diabetes research in jeopardy: the extinction of clinical diabetes researchers. Ann N Y Acad Sci. 2007 Apr; 1103:33-44.
    View in: PubMed
    Score: 0.011
  23. Shultz LD, Pearson T, King M, Giassi L, Carney L, Gott B, Lyons B, Rossini AA, Greiner DL. Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research. Ann N Y Acad Sci. 2007 Apr; 1103:77-89.
    View in: PubMed
    Score: 0.011
  24. Shultz LD, Ishikawa F, Greiner DL. Humanized mice in translational biomedical research. Nat Rev Immunol. 2007 Feb; 7(2):118-30.
    View in: PubMed
    Score: 0.011
  25. Brehm MA, Mangada J, Markees TG, Pearson T, Daniels KA, Thornley TB, Welsh RM, Rossini AA, Greiner DL. Rapid quantification of naive alloreactive T cells by TNF-alpha production and correlation with allograft rejection in mice. Blood. 2007 Jan 15; 109(2):819-26.
    View in: PubMed
    Score: 0.010
  26. Coate KC, Dai C, Singh A, Stanley J, Covington BA, Bradley A, Oladipupo F, Gong Y, Wisniewski S, Sellick K, Spears E, Poffenberger G, Schornack AMR, Bustabad A, Rodgers T, Dey N, Shultz LD, Greiner DL, Yan H, Powers AC, Chen W, Dean ED. Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners. Mol Metab. 2024 Dec; 90:102050.
    View in: PubMed
    Score: 0.009
  27. Amdare NP, Shultz LD, Greiner DL, DiLorenzo TP. Human insulin as both antigen and protector in type 1 diabetes. Eur J Immunol. 2024 Sep; 54(9):e2350949.
    View in: PubMed
    Score: 0.009
  28. Stepien TA, Singletary LA, Guerra FE, Karlinsey JE, Libby SJ, Jaslow SL, Gaggioli MR, Gibbs KD, Ko DC, Brehm MA, Greiner DL, Shultz LD, Fang FC. Nuclear factor kappa B-dependent persistence of Salmonella Typhi and Paratyphi in human macrophages. mBio. 2024 Apr 10; 15(4):e0045424.
    View in: PubMed
    Score: 0.009
  29. Walker JT, Saunders DC, Rai V, Chen HH, Orchard P, Dai C, Pettway YD, Hopkirk AL, Reihsmann CV, Tao Y, Fan S, Shrestha S, Varshney A, Petty LE, Wright JJ, Ventresca C, Agarwala S, Aramandla R, Poffenberger G, Jenkins R, Mei S, Hart NJ, Phillips S, Kang H, Greiner DL, Shultz LD, Bottino R, Liu J, Below JE, Parker SCJ, Powers AC, Brissova M. Genetic risk converges on regulatory networks mediating early type 2 diabetes. Nature. 2023 Dec; 624(7992):621-629.
    View in: PubMed
    Score: 0.009
  30. Shultz LD, Banuelos S, Lyons B, Samuels R, Burzenski L, Gott B, Lang P, Leif J, Appel M, Rossini A, Greiner DL. NOD/LtSz-Rag1nullPfpnull mice: a new model system with increased levels of human peripheral leukocyte and hematopoietic stem-cell engraftment. Transplantation. 2003 Oct 15; 76(7):1036-42.
    View in: PubMed
    Score: 0.009
  31. Pearson T, Markees TG, Serreze DV, Pierce MA, Wicker LS, Peterson LB, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Genetic separation of the transplantation tolerance and autoimmune phenotypes in NOD mice. Rev Endocr Metab Disord. 2003 Sep; 4(3):255-61.
    View in: PubMed
    Score: 0.008
  32. Doloff JC, Ma M, Sadraei A, Tam HH, Farah S, Hollister-Lock J, Vegas AJ, Veiseh O, Quiroz VM, Rakoski A, Aresta-DaSilva S, Bader AR, Griffin M, Weir GC, Brehm MA, Shultz LD, Langer R, Greiner DL, Anderson DG. Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response. Sci Adv. 2023 06 16; 9(24):eade9488.
    View in: PubMed
    Score: 0.008
  33. Shultz LD, Banuelos SJ, Leif J, Appel MC, Cunningham M, Ballen K, Burzenski L, Greiner DL. Regulation of human short-term repopulating cell (STRC) engraftment in NOD/SCID mice by host CD122+ cells. Exp Hematol. 2003 Jun; 31(6):551-8.
    View in: PubMed
    Score: 0.008
  34. Yang J, Jiao J, Draheim KM, Yang G, Yang H, Yao LC, Shultz LD, Greiner DL, Rajagopal D, Vessillier S, Maier CC, Mohanan S, Cai D, Cheng M, Brehm MA, Keck JG. Simultaneous evaluation of treatment efficacy and toxicity for bispecific T-cell engager therapeutics in a humanized mouse model. FASEB J. 2023 06; 37(6):e22995.
    View in: PubMed
    Score: 0.008
  35. Aryee KE, Shultz LD, Burzenski LM, Greiner DL, Brehm MA. NOD-scid IL2r?null mice lacking TLR4 support human immune system development and the study of human-specific innate immunity. J Leukoc Biol. 2023 05 02; 113(5):418-433.
    View in: PubMed
    Score: 0.008
  36. Derr AG, Arowosegbe A, Satish B, Redick SD, Qaisar N, Guo Z, Vanderleeden E, Trombly MI, Baer CE, Harlan DM, Greiner DL, Garber M, Wang JP. An Early Islet Transcriptional Signature Is Associated With Local Inflammation in Autoimmune Diabetes. Diabetes. 2023 Feb 01; 72(2):261-274.
    View in: PubMed
    Score: 0.008
  37. Chuprin J, Buettner H, Seedhom MO, Greiner DL, Keck JG, Ishikawa F, Shultz LD, Brehm MA. Humanized mouse models for immuno-oncology research. Nat Rev Clin Oncol. 2023 03; 20(3):192-206.
    View in: PubMed
    Score: 0.008
  38. Aryee KE, Burzenski LM, Yao LC, Keck JG, Greiner DL, Shultz LD, Brehm MA. Enhanced development of functional human NK cells in NOD-scid-IL2rgnull mice expressing human IL15. FASEB J. 2022 09; 36(9):e22476.
    View in: PubMed
    Score: 0.008
  39. Khosravi-Maharlooei M, Madley R, Borsotti C, Ferreira LMR, Sharp RC, Brehm MA, Greiner DL, Parent AV, Anderson MS, Sykes M, Creusot RJ. Modeling human T1D-associated autoimmune processes. Mol Metab. 2022 02; 56:101417.
    View in: PubMed
    Score: 0.007
  40. Greiner DL, Rossini AA, Mordes JP. Translating data from animal models into methods for preventing human autoimmune diabetes mellitus: caveat emptor and primum non nocere. Clin Immunol. 2001 Aug; 100(2):134-43.
    View in: PubMed
    Score: 0.007
  41. Roderick JE, Gallagher KM, Murphy LC, O'Connor KW, Tang K, Zhang B, Brehm MA, Greiner DL, Yu J, Zhu LJ, Green MR, Kelliher MA. Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death. Blood. 2021 01 28; 137(4):500-512.
    View in: PubMed
    Score: 0.007
  42. Dai C, Walker JT, Shostak A, Bouchi Y, Poffenberger G, Hart NJ, Jacobson DA, Calcutt MW, Bottino R, Greiner DL, Shultz LD, McGuinness OP, Dean ED, Powers AC. Dapagliflozin Does Not Directly Affect Human a or ? Cells. Endocrinology. 2020 08 01; 161(8).
    View in: PubMed
    Score: 0.007
  43. Leite NC, Sintov E, Meissner TB, Brehm MA, Greiner DL, Harlan DM, Melton DA. Modeling Type 1 Diabetes In?Vitro Using Human Pluripotent Stem Cells. Cell Rep. 2020 07 14; 32(2):107894.
    View in: PubMed
    Score: 0.007
  44. Wagar EJ, Cromwell MA, Shultz LD, Woda BA, Sullivan JL, Hesselton RM, Greiner DL. Regulation of human cell engraftment and development of EBV-related lymphoproliferative disorders in Hu-PBL-scid mice. J Immunol. 2000 Jul 01; 165(1):518-27.
    View in: PubMed
    Score: 0.007
  45. Bose S, Volpatti LR, Thiono D, Yesilyurt V, McGladrigan C, Tang Y, Facklam A, Wang A, Jhunjhunwala S, Veiseh O, Hollister-Lock J, Bhattacharya C, Weir GC, Greiner DL, Langer R, Anderson DG. A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells. Nat Biomed Eng. 2020 08; 4(8):814-826.
    View in: PubMed
    Score: 0.007
  46. Shultz LD, Lang PA, Christianson SW, Gott B, Lyons B, Umeda S, Leiter E, Hesselton R, Wagar EJ, Leif JH, Kollet O, Lapidot T, Greiner DL. NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells. J Immunol. 2000 Mar 01; 164(5):2496-507.
    View in: PubMed
    Score: 0.007
  47. Dai C, Walker JT, Shostak A, Padgett A, Spears E, Wisniewski S, Poffenberger G, Aramandla R, Dean ED, Prasad N, Levy SE, Greiner DL, Shultz LD, Bottino R, Powers AC. Tacrolimus- and sirolimus-induced human ? cell dysfunction is reversible and preventable. JCI Insight. 2020 01 16; 5(1).
    View in: PubMed
    Score: 0.007
  48. Redick SD, Leehy L, Rittenhouse AR, Blodgett DM, Derr AG, Kucukural A, Garber MG, Shultz LD, Greiner DL, Wang JP, Harlan DM, Bortell R, Jurczyk A. Recovery of viable endocrine-specific cells and transcriptomes from human pancreatic islet-engrafted mice. FASEB J. 2020 01; 34(1):1901-1911.
    View in: PubMed
    Score: 0.007
  49. Karlinsey JE, Stepien TA, Mayho M, Singletary LA, Bingham-Ramos LK, Brehm MA, Greiner DL, Shultz LD, Gallagher LA, Bawn M, Kingsley RA, Libby SJ, Fang FC. Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features. Cell Host Microbe. 2019 09 11; 26(3):426-434.e6.
    View in: PubMed
    Score: 0.006
  50. Youngblood BA, Brock EC, Leung J, Falahati R, Bryce PJ, Bright J, Williams J, Shultz LD, Greiner DL, Brehm MA, Bebbington C, Tomasevic N. AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice. Int Arch Allergy Immunol. 2019; 180(2):91-102.
    View in: PubMed
    Score: 0.006
  51. Shultz LD, Keck J, Burzenski L, Jangalwe S, Vaidya S, Greiner DL, Brehm MA. Humanized mouse models of immunological diseases and precision medicine. Mamm Genome. 2019 06; 30(5-6):123-142.
    View in: PubMed
    Score: 0.006
  52. Rossini AA, Mordes JP, Markees TG, Phillips NE, Gordon EJ, Greiner DL. Induction of islet transplantation tolerance using donor specific transfusion and anti-CD154 monoclonal antibody. Transplant Proc. 1999 Feb-Mar; 31(1-2):629-32.
    View in: PubMed
    Score: 0.006
  53. Martin AM, Blankenhorn EP, Maxson MN, Zhao M, Leif J, Mordes JP, Greiner DL. Non-major histocompatibility complex-linked diabetes susceptibility loci on chromosomes 4 and 13 in a backcross of the DP-BB/Wor rat to the WF rat. Diabetes. 1999 Jan; 48(1):50-8.
    View in: PubMed
    Score: 0.006
  54. Gawron MA, Duval M, Carbone C, Jaiswal S, Wallace A, Martin JC, Dauphin A, Brehm MA, Greiner DL, Shultz LD, Luban J, Cavacini LA. Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1. J Immunol. 2019 02 01; 202(3):799-804.
    View in: PubMed
    Score: 0.006
  55. Bahmani B, Uehara M, Ordikhani F, Li X, Jiang L, Banouni N, Ichimura T, Kasinath V, Eskandari SK, Annabi N, Bromberg JS, Shultz LD, Greiner DL, Abdi R. Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery. EBioMedicine. 2018 Dec; 38:79-88.
    View in: PubMed
    Score: 0.006
  56. Saunders DC, Brissova M, Phillips N, Shrestha S, Walker JT, Aramandla R, Poffenberger G, Flaherty DK, Weller KP, Pelletier J, Cooper T, Goff MT, Virostko J, Shostak A, Dean ED, Greiner DL, Shultz LD, Prasad N, Levy SE, Carnahan RH, Dai C, S?vigny J, Powers AC. Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic ? Cells for In?Vitro and In?Vivo Analysis. Cell Metab. 2019 03 05; 29(3):745-754.e4.
    View in: PubMed
    Score: 0.006
  57. Brehm MA, Kenney LL, Wiles MV, Low BE, Tisch RM, Burzenski L, Mueller C, Greiner DL, Shultz LD. Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression. FASEB J. 2019 03; 33(3):3137-3151.
    View in: PubMed
    Score: 0.006
  58. Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, Grey ST, Tang Q, Roep B, Ricordi C, Naji A, Orlando G, Anderson DG, Poznansky M, Ludwig B, Tomei A, Greiner DL, Graham M, Carpenter M, Migliaccio G, D'Amour K, Hering B, Piemonti L, Berney T, Rickels M, Kay T, Adams A. Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells. Transplantation. 2018 08; 102(8):1223-1229.
    View in: PubMed
    Score: 0.006
  59. Brissova M, Haliyur R, Saunders D, Shrestha S, Dai C, Blodgett DM, Bottino R, Campbell-Thompson M, Aramandla R, Poffenberger G, Lindner J, Pan FC, von Herrath MG, Greiner DL, Shultz LD, Sanyoura M, Philipson LH, Atkinson M, Harlan DM, Levy SE, Prasad N, Stein R, Powers AC. a Cell Function and Gene Expression Are Compromised in Type 1 Diabetes. Cell Rep. 2018 03 06; 22(10):2667-2676.
    View in: PubMed
    Score: 0.006
  60. Wang M, Yao LC, Cheng M, Cai D, Martinek J, Pan CX, Shi W, Ma AH, De Vere White RW, Airhart S, Liu ET, Banchereau J, Brehm MA, Greiner DL, Shultz LD, Palucka K, Keck JG. Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy. FASEB J. 2018 03; 32(3):1537-1549.
    View in: PubMed
    Score: 0.006
  61. Foy TM, McIlraith M, Masters SR, Dunn JJ, Rossini AA, Shultz LD, Hesselton RA, Wagar EJ, Lipsky PE, Noelle RJ, Greiner DL. Blockade of CD40-CD154 interferes with human T cell engraftment in scid mice. Cell Transplant. 1998 Jan-Feb; 7(1):25-35.
    View in: PubMed
    Score: 0.006
  62. Greiner DL, Hesselton RA, Shultz LD. SCID mouse models of human stem cell engraftment. Stem Cells. 1998; 16(3):166-77.
    View in: PubMed
    Score: 0.006
  63. Borel F, Tang Q, Gernoux G, Greer C, Wang Z, Barzel A, Kay MA, Shultz LD, Greiner DL, Flotte TR, Brehm MA, Mueller C. Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of a-1 Antitrypsin Deficiency. Mol Ther. 2017 11 01; 25(11):2477-2489.
    View in: PubMed
    Score: 0.006
  64. Dai C, Hang Y, Shostak A, Poffenberger G, Hart N, Prasad N, Phillips N, Levy SE, Greiner DL, Shultz LD, Bottino R, Kim SK, Powers AC. Age-dependent human ? cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. J Clin Invest. 2017 Oct 02; 127(10):3835-3844.
    View in: PubMed
    Score: 0.006
  65. Kooreman NG, de Almeida PE, Stack JP, Nelakanti RV, Diecke S, Shao NY, Swijnenburg RJ, Sanchez-Freire V, Matsa E, Liu C, Connolly AJ, Hamming JF, Quax PHA, Brehm MA, Greiner DL, Shultz LD, Wu JC. Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics. Cell Rep. 2017 Aug 22; 20(8):1978-1990.
    View in: PubMed
    Score: 0.006
  66. Roberts FR, Hupple C, Norowski E, Walsh NC, Przewozniak N, Aryee KE, Van Dessel FM, Jurczyk A, Harlan DM, Greiner DL, Bortell R, Yang C. Possible type 1 diabetes risk prediction: Using ultrasound imaging to assess pancreas inflammation in the inducible autoimmune diabetes BBDR model. PLoS One. 2017; 12(6):e0178641.
    View in: PubMed
    Score: 0.005
  67. Lee J, Dykstra B, Spencer JA, Kenney LL, Greiner DL, Shultz LD, Brehm MA, Lin CP, Sackstein R, Rossi DJ. mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell-derived hematopoietic progenitors. J Clin Invest. 2017 Jun 01; 127(6):2433-2437.
    View in: PubMed
    Score: 0.005
  68. Filion TM, Skelly JD, Huang H, Greiner DL, Ayers DC, Song J. Impaired osteogenesis of T1DM bone marrow-derived stromal cells and periosteum-derived cells and their differential in-vitro responses to growth factor rescue. Stem Cell Res Ther. 2017 03 11; 8(1):65.
    View in: PubMed
    Score: 0.005
  69. Greiner DL, Malkani S, Kanaitsuka T, Bortell R, Doukas J, Rigby M, Whalen B, Stevens LA, Moss J, Mordes JP, Rossini AA. The T cell marker RT6 in a rat model of autoimmune diabetes. Adv Exp Med Biol. 1997; 419:209-16.
    View in: PubMed
    Score: 0.005
  70. Walsh NC, Kenney LL, Jangalwe S, Aryee KE, Greiner DL, Brehm MA, Shultz LD. Humanized Mouse Models of Clinical Disease. Annu Rev Pathol. 2017 Jan 24; 12:187-215.
    View in: PubMed
    Score: 0.005
  71. Bahal R, Ali McNeer N, Quijano E, Liu Y, Sulkowski P, Turchick A, Lu YC, Bhunia DC, Manna A, Greiner DL, Brehm MA, Cheng CJ, L?pez-Gir?ldez F, Ricciardi A, Beloor J, Krause DS, Kumar P, Gallagher PG, Braddock DT, Mark Saltzman W, Ly DH, Glazer PM. In vivo correction of anaemia in ?-thalassemic mice by ?PNA-mediated gene editing with nanoparticle delivery. Nat Commun. 2016 10 26; 7:13304.
    View in: PubMed
    Score: 0.005
  72. Moser J, van Ark J, van Dijk MC, Greiner DL, Shultz LD, van Goor H, Hillebrands JL. Distinct Differences on Neointima Formation in Immunodeficient and Humanized Mice after Carotid or Femoral Arterial Injury. Sci Rep. 2016 10 19; 6:35387.
    View in: PubMed
    Score: 0.005
  73. Boudreau JE, Liu XR, Zhao Z, Zhang A, Shultz LD, Greiner DL, Dupont B, Hsu KC. Cell-Extrinsic MHC Class I Molecule Engagement Augments Human NK Cell Education Programmed by Cell-Intrinsic MHC Class I. Immunity. 2016 08 16; 45(2):280-91.
    View in: PubMed
    Score: 0.005
  74. Ali R, Babad J, Follenzi A, Gebe JA, Brehm MA, Nepom GT, Shultz LD, Greiner DL, DiLorenzo TP. Genetically modified human CD4(+) T cells can be evaluated in?vivo without lethal graft-versus-host disease. Immunology. 2016 08; 148(4):339-51.
    View in: PubMed
    Score: 0.005
  75. Mercado-Lubo R, Zhang Y, Zhao L, Rossi K, Wu X, Zou Y, Castillo A, Leonard J, Bortell R, Greiner DL, Shultz LD, Han G, McCormick BA. A Salmonella nanoparticle mimic overcomes multidrug resistance in tumours. Nat Commun. 2016 07 25; 7:12225.
    View in: PubMed
    Score: 0.005
  76. Dai C, Kayton NS, Shostak A, Poffenberger G, Cyphert HA, Aramandla R, Thompson C, Papagiannis IG, Emfinger C, Shiota M, Stafford JM, Greiner DL, Herrera PL, Shultz LD, Stein R, Powers AC. Stress-impaired transcription factor expression and insulin secretion in transplanted human islets. J Clin Invest. 2016 05 02; 126(5):1857-70.
    View in: PubMed
    Score: 0.005
  77. Bryce PJ, Falahati R, Kenney LL, Leung J, Bebbington C, Tomasevic N, Krier RA, Hsu CL, Shultz LD, Greiner DL, Brehm MA. Humanized mouse model of mast cell-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis. J Allergy Clin Immunol. 2016 09; 138(3):769-779.
    View in: PubMed
    Score: 0.005
  78. Goel HL, Pursell B, Shultz LD, Greiner DL, Brekken RA, Vander Kooi CW, Mercurio AM. P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer. Cell Rep. 2016 Mar 08; 14(9):2193-2208.
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    Score: 0.005
  79. Vegas AJ, Veiseh O, Doloff JC, Ma M, Tam HH, Bratlie K, Li J, Bader AR, Langan E, Olejnik K, Fenton P, Kang JW, Hollister-Locke J, Bochenek MA, Chiu A, Siebert S, Tang K, Jhunjhunwala S, Aresta-Dasilva S, Dholakia N, Thakrar R, Vietti T, Chen M, Cohen J, Siniakowicz K, Qi M, McGarrigle J, Graham AC, Lyle S, Harlan DM, Greiner DL, Oberholzer J, Weir GC, Langer R, Anderson DG. Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates. Nat Biotechnol. 2016 03; 34(3):345-52.
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    Score: 0.005
  80. Vegas AJ, Veiseh O, G?rtler M, Millman JR, Pagliuca FW, Bader AR, Doloff JC, Li J, Chen M, Olejnik K, Tam HH, Jhunjhunwala S, Langan E, Aresta-Dasilva S, Gandham S, McGarrigle JJ, Bochenek MA, Hollister-Lock J, Oberholzer J, Greiner DL, Weir GC, Melton DA, Langer R, Anderson DG. Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice. Nat Med. 2016 Mar; 22(3):306-11.
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    Score: 0.005
  81. Greiner DL, Shultz LD, Deluca D, Leif JH, Christianson SW, Hesselton RM. HIV-1 infectivity of human T cells in a human/murine chimeric fetal thymic organ culture system. In Vivo. 1996 Jan-Feb; 10(1):33-7.
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    Score: 0.005
  82. Hasgur S, Aryee KE, Shultz LD, Greiner DL, Brehm MA. Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells. Methods Mol Biol. 2016; 1438:67-78.
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    Score: 0.005
  83. Serreze DV, Leiter EH, Hanson MS, Christianson SW, Shultz LD, Hesselton RM, Greiner DL. Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells. Diabetes. 1995 Dec; 44(12):1392-8.
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    Score: 0.005
  84. Kenney LL, Shultz LD, Greiner DL, Brehm MA. Humanized Mouse Models for Transplant Immunology. Am J Transplant. 2016 Feb; 16(2):389-97.
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    Score: 0.005
  85. Jurczyk A, Nowosielska A, Przewozniak N, Aryee KE, DiIorio P, Blodgett D, Yang C, Campbell-Thompson M, Atkinson M, Shultz L, Rittenhouse A, Harlan D, Greiner D, Bortell R. Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic ?-cell function via glycogen synthase kinase-3?. FASEB J. 2016 Feb; 30(2):983-93.
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    Score: 0.005
  86. Sewald X, Ladinsky MS, Uchil PD, Beloor J, Pi R, Herrmann C, Motamedi N, Murooka TT, Brehm MA, Greiner DL, Shultz LD, Mempel TR, Bjorkman PJ, Kumar P, Mothes W. Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection. Science. 2015 Oct 30; 350(6260):563-567.
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    Score: 0.005
  87. Li S, Ling C, Zhong L, Li M, Su Q, He R, Tang Q, Greiner DL, Shultz LD, Brehm MA, Flotte TR, Mueller C, Srivastava A, Gao G. Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors. Mol Ther. 2015 Dec; 23(12):1867-76.
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    Score: 0.005
  88. Samanta S, Sun H, Goel HL, Pursell B, Chang C, Khan A, Greiner DL, Cao S, Lim E, Shultz LD, Mercurio AM. IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG. Oncogene. 2016 Mar 03; 35(9):1111-21.
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    Score: 0.005
  89. Blodgett DM, Nowosielska A, Afik S, Pechhold S, Cura AJ, Kennedy NJ, Kim S, Kucukural A, Davis RJ, Kent SC, Greiner DL, Garber MG, Harlan DM, diIorio P. Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets. Diabetes. 2015 Sep; 64(9):3172-81.
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    Score: 0.005
  90. Nostro MC, Sarangi F, Yang C, Holland A, Elefanty AG, Stanley EG, Greiner DL, Keller G. Efficient generation of NKX6-1+ pancreatic progenitors from multiple human pluripotent stem cell lines. Stem Cell Reports. 2015 Apr 14; 4(4):591-604.
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    Score: 0.005
  91. Greiner DL, Shultz LD, Yates J, Appel MC, Perdrizet G, Hesselton RM, Schweitzer I, Beamer WG, Shultz KL, Pelsue SC, et al. Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice. Am J Pathol. 1995 Apr; 146(4):888-902.
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    Score: 0.005
  92. Babad J, Mukherjee G, Follenzi A, Ali R, Roep BO, Shultz LD, Santamaria P, Yang OO, Goldstein H, Greiner DL, DiLorenzo TP. Generation of ? cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice. Clin Exp Immunol. 2015 Mar; 179(3):398-413.
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    Score: 0.005
  93. Rossini AA, Handler ES, Mordes JP, Greiner DL. Human autoimmune diabetes mellitus: lessons from BB rats and NOD mice--Caveat emptor. Clin Immunol Immunopathol. 1995 Jan; 74(1):2-9.
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    Score: 0.005
  94. Shultz LD, Schweitzer PA, Christianson SW, Gott B, Schweitzer IB, Tennent B, McKenna S, Mobraaten L, Rajan TV, Greiner DL, et al. Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice. J Immunol. 1995 Jan 01; 154(1):180-91.
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    Score: 0.005
  95. Chang C, Goel HL, Gao H, Pursell B, Shultz LD, Greiner DL, Ingerpuu S, Patarroyo M, Cao S, Lim E, Mao J, McKee KK, Yurchenco PD, Mercurio AM. A laminin 511 matrix is regulated by TAZ and functions as the ligand for the a6B?1 integrin to sustain breast cancer stem cells. Genes Dev. 2015 Jan 01; 29(1):1-6.
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    Score: 0.005
  96. Gallagher GR, Brehm MA, Finberg RW, Barton BA, Shultz LD, Greiner DL, Bortell R, Wang JP. Viral infection of engrafted human islets leads to diabetes. Diabetes. 2015 Apr; 64(4):1358-69.
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    Score: 0.005
  97. Pagliuca FW, Millman JR, G?rtler M, Segel M, Van Dervort A, Ryu JH, Peterson QP, Greiner D, Melton DA. Generation of functional human pancreatic ? cells in vitro. Cell. 2014 Oct 09; 159(2):428-39.
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    Score: 0.005
  98. Wilson EM, Bial J, Tarlow B, Bial G, Jensen B, Greiner DL, Brehm MA, Grompe M. Extensive double humanization of both liver and hematopoiesis in FRGN mice. Stem Cell Res. 2014 Nov; 13(3 Pt A):404-12.
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    Score: 0.005
  99. Jaiswal S, Smith K, Ramirez A, Woda M, Pazoles P, Shultz LD, Greiner DL, Brehm MA, Mathew A. Dengue virus infection induces broadly cross-reactive human IgM antibodies that recognize intact virions in humanized BLT-NSG mice. Exp Biol Med (Maywood). 2015 Jan; 240(1):67-78.
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    Score: 0.005
  100. Purwana I, Zheng J, Li X, Deurloo M, Son DO, Zhang Z, Liang C, Shen E, Tadkase A, Feng ZP, Li Y, Hasilo C, Paraskevas S, Bortell R, Greiner DL, Atkinson M, Prud'homme GJ, Wang Q. GABA promotes human ?-cell proliferation and modulates glucose homeostasis. Diabetes. 2014 Dec; 63(12):4197-205.
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    Score: 0.004
  101. Trabucco SE, Gerstein RM, Evens AM, Bradner JE, Shultz LD, Greiner DL, Zhang H. Inhibition of bromodomain proteins for the treatment of human diffuse large B-cell lymphoma. Clin Cancer Res. 2015 Jan 01; 21(1):113-22.
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    Score: 0.004
  102. Maykel J, Liu JH, Li H, Shultz LD, Greiner DL, Houghton J. NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer. Dig Dis Sci. 2014 Jun; 59(6):1169-79.
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    Score: 0.004
  103. Goel HL, Gritsko T, Pursell B, Chang C, Shultz LD, Greiner DL, Norum JH, Toftgard R, Shaw LM, Mercurio AM. Regulated splicing of the a6 integrin cytoplasmic domain determines the fate of breast cancer stem cells. Cell Rep. 2014 May 08; 7(3):747-61.
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    Score: 0.004
  104. Brehm MA, Wiles MV, Greiner DL, Shultz LD. Generation of improved humanized mouse models for human infectious diseases. J Immunol Methods. 2014 Aug; 410:3-17.
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    Score: 0.004
  105. Knoechel B, Roderick JE, Williamson KE, Zhu J, Lohr JG, Cotton MJ, Gillespie SM, Fernandez D, Ku M, Wang H, Piccioni F, Silver SJ, Jain M, Pearson D, Kluk MJ, Ott CJ, Shultz LD, Brehm MA, Greiner DL, Gutierrez A, Stegmaier K, Kung AL, Root DE, Bradner JE, Aster JC, Kelliher MA, Bernstein BE. An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia. Nat Genet. 2014 Apr; 46(4):364-70.
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    Score: 0.004
  106. Roderick JE, Tesell J, Shultz LD, Brehm MA, Greiner DL, Harris MH, Silverman LB, Sallan SE, Gutierrez A, Look AT, Qi J, Bradner JE, Kelliher MA. c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells. Blood. 2014 Feb 13; 123(7):1040-50.
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    Score: 0.004
  107. Lee J, Brehm MA, Greiner D, Shultz LD, Kornfeld H. Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice. BMC Immunol. 2013 Dec 07; 14:53.
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    Score: 0.004
  108. Dou S, Wang Y, Barton B, Chen L, Rusckowski M, Shultz LD, Greiner DL, Liu G. Comparison between two labeled agents in mice using a coinjection-ratio approach in contrast to a conventional group approach. Nucl Med Biol. 2014 Jan; 41(1):127-31.
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    Score: 0.004
  109. Brehm MA, Jouvet N, Greiner DL, Shultz LD. Humanized mice for the study of infectious diseases. Curr Opin Immunol. 2013 Aug; 25(4):428-35.
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    Score: 0.004
  110. Wheeler LA, Vrbanac V, Trifonova R, Brehm MA, Gilboa-Geffen A, Tanno S, Greiner DL, Luster AD, Tager AM, Lieberman J. Durable knockdown and protection from HIV transmission in humanized mice treated with gel-formulated CD4 aptamer-siRNA chimeras. Mol Ther. 2013 Jul; 21(7):1378-89.
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    Score: 0.004
  111. Goel HL, Pursell B, Chang C, Shaw LM, Mao J, Simin K, Kumar P, Vander Kooi CW, Shultz LD, Greiner DL, Norum JH, Toftgard R, Kuperwasser C, Mercurio AM. GLI1 regulates a novel neuropilin-2/a6?1 integrin based autocrine pathway that contributes to breast cancer initiation. EMBO Mol Med. 2013 Apr; 5(4):488-508.
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    Score: 0.004
  112. Hickey RD, Galivo F, Schug J, Brehm MA, Haft A, Wang Y, Benedetti E, Gu G, Magnuson MA, Shultz LD, Lagasse E, Greiner DL, Kaestner KH, Grompe M. Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming. Stem Cell Res. 2013 Jul; 11(1):503-15.
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    Score: 0.004
  113. Unger WW, Pearson T, Abreu JR, Laban S, van der Slik AR, der Kracht SM, Kester MG, Serreze DV, Shultz LD, Griffioen M, Drijfhout JW, Greiner DL, Roep BO. Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice. PLoS One. 2012; 7(11):e49213.
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    Score: 0.004
  114. McNeer NA, Schleifman EB, Cuthbert A, Brehm M, Jackson A, Cheng C, Anandalingam K, Kumar P, Shultz LD, Greiner DL, Mark Saltzman W, Glazer PM. Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo. Gene Ther. 2013 Jun; 20(6):658-69.
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    Score: 0.004
  115. Oslowski CM, Hara T, O'Sullivan-Murphy B, Kanekura K, Lu S, Hara M, Ishigaki S, Zhu LJ, Hayashi E, Hui ST, Greiner D, Kaufman RJ, Bortell R, Urano F. Thioredoxin-interacting protein mediates ER stress-induced ? cell death through initiation of the inflammasome. Cell Metab. 2012 Aug 08; 16(2):265-73.
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    Score: 0.004
  116. Jaiswal S, Pazoles P, Woda M, Shultz LD, Greiner DL, Brehm MA, Mathew A. Enhanced humoral and HLA-A2-restricted dengue virus-specific T-cell responses in humanized BLT NSG mice. Immunology. 2012 Jul; 136(3):334-43.
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    Score: 0.004
  117. Greiner DL, Rajan TV, Shultz LD. Animal models for immunodeficiency diseases. Immunol Today. 1992 Apr; 13(4):116-7.
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    Score: 0.004
  118. Rajan TV, Nelson FK, Cupp E, Schultz LD, Greiner DL. Survival of Onchocerca volvulus in nodules implanted in immunodeficient rodents. J Parasitol. 1992 Feb; 78(1):160-3.
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    Score: 0.004
  119. Priyadharshini B, Greiner DL, Brehm MA. T-cell activation and transplantation tolerance. Transplant Rev (Orlando). 2012 Jul; 26(3):212-22.
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    Score: 0.004
  120. Diiorio P, Jurczyk A, Yang C, Racki WJ, Brehm MA, Atkinson MA, Powers AC, Shultz LD, Greiner DL, Bortell R. Hyperglycemia-induced proliferation of adult human beta cells engrafted into spontaneously diabetic immunodeficient NOD-Rag1null IL2r?null Ins2Akita mice. Pancreas. 2011 Oct; 40(7):1147-9.
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    Score: 0.004
  121. Schleifman EB, Bindra R, Leif J, del Campo J, Rogers FA, Uchil P, Kutsch O, Shultz LD, Kumar P, Greiner DL, Glazer PM. Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids. Chem Biol. 2011 Sep 23; 18(9):1189-98.
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    Score: 0.004
  122. Niens M, Grier AE, Marron M, Kay TW, Greiner DL, Serreze DV. Prevention of "Humanized" diabetogenic CD8 T-cell responses in HLA-transgenic NOD mice by a multipeptide coupled-cell approach. Diabetes. 2011 Apr; 60(4):1229-36.
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    Score: 0.004
  123. Libby SJ, Brehm MA, Greiner DL, Shultz LD, McClelland M, Smith KD, Cookson BT, Karlinsey JE, Kinkel TL, Porwollik S, Canals R, Cummings LA, Fang FC. Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection. Proc Natl Acad Sci U S A. 2010 Aug 31; 107(35):15589-94.
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    Score: 0.003
  124. Kruger AJ, Yang C, Lipson KL, Pino SC, Leif JH, Hogan CM, Whalen BJ, Guberski DL, Lee Y, Unger RH, Greiner DL, Rossini AA, Bortell R. Leptin treatment confers clinical benefit at multiple stages of virally induced type 1 diabetes in BB rats. Autoimmunity. 2011 Mar; 44(2):137-48.
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    Score: 0.003
  125. Brehm MA, Bortell R, Diiorio P, Leif J, Laning J, Cuthbert A, Yang C, Herlihy M, Burzenski L, Gott B, Foreman O, Powers AC, Greiner DL, Shultz LD. Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice. Diabetes. 2010 Sep; 59(9):2265-70.
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    Score: 0.003
  126. Liu G, Dou S, Rusckowski M, Greiner D, Hnatowich D. Preparation of (111)In-DTPA morpholino oligomer for low abdominal accumulation. Appl Radiat Isot. 2010 Sep; 68(9):1709-14.
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    Score: 0.003
  127. Pino S, Brehm MA, Covassin-Barberis L, King M, Gott B, Chase TH, Wagner J, Burzenski L, Foreman O, Greiner DL, Shultz LD. Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease. Methods Mol Biol. 2010; 602:105-17.
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    Score: 0.003
  128. Subramanya S, Kim SS, Abraham S, Yao J, Kumar M, Kumar P, Haridas V, Lee SK, Shultz LD, Greiner D, N M, Shankar P. Targeted delivery of small interfering RNA to human dendritic cells to suppress dengue virus infection and associated proinflammatory cytokine production. J Virol. 2010 Mar; 84(5):2490-501.
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    Score: 0.003
  129. Ishigaki S, Fonseca SG, Oslowski CM, Jurczyk A, Shearstone JR, Zhu LJ, Permutt MA, Greiner DL, Bortell R, Urano F. AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1. Cell Death Differ. 2010 May; 17(5):774-86.
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    Score: 0.003
  130. Jaiswal S, Pearson T, Friberg H, Shultz LD, Greiner DL, Rothman AL, Mathew A. Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice. PLoS One. 2009 Oct 05; 4(10):e7251.
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    Score: 0.003
  131. Tirabassi RS, Guberski DL, Blankenhorn EP, Leif JH, Woda BA, Liu Z, Winans D, Greiner DL, Mordes JP. Infection with viruses from several families triggers autoimmune diabetes in LEW*1WR1 rats: prevention of diabetes by maternal immunization. Diabetes. 2010 Jan; 59(1):110-8.
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    Score: 0.003
  132. Mordes JP, Cort L, Norowski E, Leif J, Fuller JM, Lernmark A, Greiner DL, Blankenhorn EP. Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus. Mamm Genome. 2009 Mar; 20(3):162-9.
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    Score: 0.003
  133. Rossini AA, Mordes JP, Greiner DL. The pathogenesis of autoimmune diabetes mellitus. Curr Opin Immunol. 1989-1990 Apr; 2(4):598-603.
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    Score: 0.003
  134. Bortell R, Pino SC, Greiner DL, Zipris D, Rossini AA. Closing the circle between the bedside and the bench: Toll-like receptors in models of virally induced diabetes. Ann N Y Acad Sci. 2008 Dec; 1150:112-22.
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    Score: 0.003
  135. Schmidt MR, Appel MC, Giassi LJ, Greiner DL, Shultz LD, Woodland RT. Human BLyS facilitates engraftment of human PBL derived B cells in immunodeficient mice. PLoS One. 2008 Sep 11; 3(9):e3192.
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    Score: 0.003
  136. Kumar P, Ban HS, Kim SS, Wu H, Pearson T, Greiner DL, Laouar A, Yao J, Haridas V, Habiro K, Yang YG, Jeong JH, Lee KY, Kim YH, Kim SW, Peipp M, Fey GH, Manjunath N, Shultz LD, Lee SK, Shankar P. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice. Cell. 2008 Aug 22; 134(4):577-86.
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    Score: 0.003
  137. Pearson T, Greiner DL, Shultz LD. Creation of "humanized" mice to study human immunity. Curr Protoc Immunol. 2008 May; Chapter 15:15.21.1-15.21.21.
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    Score: 0.003
  138. Pearson T, Greiner DL, Shultz LD. Humanized SCID mouse models for biomedical research. Curr Top Microbiol Immunol. 2008; 324:25-51.
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    Score: 0.003
  139. Miller DM, Thornley TB, Greiner DL, Rossini AA. Viral infection: a potent barrier to transplantation tolerance. Clin Dev Immunol. 2008; 2008:742810.
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    Score: 0.003
  140. Greiner DL, Angelillo M, Mordes JP, Handler ES, Mojcik CF, Nakamura N, Rossini AA. Regulatory T cell control of autoimmune destruction of beta cells in the BB rat. Adv Exp Med Biol. 1988; 246:379-85.
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    Score: 0.003
  141. Shultz LD, Lyons BL, Burzenski LM, Gott B, Chen X, Chaleff S, Kotb M, Gillies SD, King M, Mangada J, Greiner DL, Handgretinger R. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol. 2005 May 15; 174(10):6477-89.
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    Score: 0.002
  142. Banuelos SJ, Shultz LD, Greiner DL, Burzenski LM, Gott B, Lyons BL, Rossini AA, Appel MC. Rejection of human islets and human HLA-A2.1 transgenic mouse islets by alloreactive human lymphocytes in immunodeficient NOD-scid and NOD-Rag1(null)Prf1(null) mice. Clin Immunol. 2004 Sep; 112(3):273-83.
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    Score: 0.002
  143. Hornum L, DeScipio C, Markholst H, Troutman SA, Novak S, Leif J, Greiner D, Mordes JP, Blankenhorn EP. Comparative mapping of rat Iddm4 to segments on HSA7 and MMU6. Mamm Genome. 2004 Jan; 15(1):53-61.
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    Score: 0.002
  144. Turgeon NA, Banuelos SJ, Shultz LD, Lyons BL, Iwakoshi N, Greiner DL, Mordes JP, Rossini AA, Appel MC. Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice. Exp Biol Med (Maywood). 2003 Oct; 228(9):1096-104.
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    Score: 0.002
  145. Seung E, Mordes JP, Greiner DL, Rossini AA. Induction of tolerance for islet transplantation for type 1 diabetes. Curr Diab Rep. 2003 Aug; 3(4):329-35.
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    Score: 0.002
  146. Rossini AA, Mordes JP, Greiner DL, Stoff JS. Islet cell transplantation tolerance. Transplantation. 2001 Oct 27; 72(8 Suppl):S43-6.
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    Score: 0.002
  147. Ballen KK, Valinski H, Greiner D, Shultz LD, Becker PS, Hsieh CC, Stewart FM, Quesenberry PJ. Variables to predict engraftment of umbilical cord blood into immunodeficient mice: usefulness of the non-obese diabetic--severe combined immunodeficient assay. Br J Haematol. 2001 Jul; 114(1):211-8.
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    Score: 0.002
  148. Kollet O, Peled A, Byk T, Ben-Hur H, Greiner D, Shultz L, Lapidot T. beta2 microglobulin-deficient (B2m(null)) NOD/SCID mice are excellent recipients for studying human stem cell function. Blood. 2000 May 15; 95(10):3102-5.
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    Score: 0.002
  149. Ballen K, Becker PS, Greiner D, Valinski H, Shearin D, Berrios V, Dooner G, Hsieh CC, Wuu J, Shultz L, Cerny J, Leif J, Stewart FM, Quesenberry P. Effect of ex vivo cytokine treatment on human cord blood engraftment in NOD-scid mice. Br J Haematol. 2000 Mar; 108(3):629-40.
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    Score: 0.002
  150. Rossini AA, Greiner DL, Mordes JP. Induction of immunologic tolerance for transplantation. Physiol Rev. 1999 Jan; 79(1):99-141.
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    Score: 0.002
  151. Kaufmann R, Greiner D, Kippenberger S, Bernd A. Grafting of in vitro cultured melanocytes onto laser-ablated lesions in vitiligo. Acta Derm Venereol. 1998 Mar; 78(2):136-8.
    View in: PubMed
    Score: 0.001
  152. Christianson SW, Greiner DL, Hesselton RA, Leif JH, Wagar EJ, Schweitzer IB, Rajan TV, Gott B, Roopenian DC, Shultz LD. Enhanced human CD4+ T cell engraftment in beta2-microglobulin-deficient NOD-scid mice. J Immunol. 1997 Apr 15; 158(8):3578-86.
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    Score: 0.001
  153. Christianson SW, Greiner DL, Schweitzer IB, Gott B, Beamer GL, Schweitzer PA, Hesselton RM, Shultz LD. Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice. Cell Immunol. 1996 Aug 01; 171(2):186-99.
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    Score: 0.001
  154. Rajan TV, Greiner DL, Yates JA, Shultz LD. Growth of the human filarial parasite Brugia malayi in mice lacking major histocompatibility complex class II antigen expression. Acta Trop. 1996 May; 61(3):267-71.
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    Score: 0.001
  155. Mordes JP, Schirf B, Roipko D, Greiner DL, Weiner H, Nelson P, Rossini AA. Oral insulin does not prevent insulin-dependent diabetes mellitus in BB rats. Ann N Y Acad Sci. 1996 Feb 13; 778:418-21.
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    Score: 0.001
  156. Lowry PA, Shultz LD, Greiner DL, Hesselton RM, Kittler EL, Tiarks CY, Rao SS, Reilly J, Leif JH, Ramshaw H, Stewart FM, Quesenberry PJ. Improved engraftment of human cord blood stem cells in NOD/LtSz-scid/scid mice after irradiation or multiple-day injections into unirradiated recipients. Biol Blood Marrow Transplant. 1996 Feb; 2(1):15-23.
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    Score: 0.001
  157. Hesselton RM, Greiner DL, Mordes JP, Rajan TV, Sullivan JL, Shultz LD. High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice. J Infect Dis. 1995 Oct; 172(4):974-82.
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    Score: 0.001
  158. McKenna SD, Medlock ES, Greiner DL, Goldschneider I. A selective culture system for generating terminal deoxynucleotidyl transferase-positive lymphoid precursor cells in vitro. IV. Properties and developmental relationships of the lymphoid cells in the adherent and nonadherent compartments of the culture. Exp Hematol. 1994 Nov; 22(12):1164-70.
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    Score: 0.001
  159. Tafuri A, Bowers WE, Handler ES, Appel M, Lew R, Greiner D, Mordes JP, Rossini AA. High stimulatory activity of dendritic cells from diabetes-prone BioBreeding/Worcester rats exposed to macrophage-derived factors. J Clin Invest. 1993 May; 91(5):2040-8.
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    Score: 0.001
  160. Nelson FK, Greiner DL, Shultz LD, Rajan TV. The immunodeficient scid mouse as a model for human lymphatic filariasis. J Exp Med. 1991 Mar 01; 173(3):659-63.
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    Score: 0.001
  161. Rossini AA, Handler ES, Greiner DL, Mordes JP. Insulin dependent diabetes mellitus hypothesis of autoimmunity. Autoimmunity. 1991; 8(3):221-35.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.