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Andrew Karellas PhD

TitleAdjunct Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentRadiology
AddressUniversity of Arizona College of Medicine
1609 N Warren Ave, Building 211, Room 138
Tucson AZ 85724
Phone520-626-3306
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentRadiology


    Collapse Biography 
    Collapse education and training
    Worcester State College, Worcester, MA, United StatesBSChemistry
    California State University, Los Angeles, Los Angeles, CA, United StatesPHDMedical Physics
    Collapse awards and honors
    1983Distinguished Scholar Award, University of California, Los Angeles (UCLA)
    1984The Crump (Institute) Prize for Excellence in Medical Engineering, University of California, Los Angeles (UCLA)
    2001Fellow of the American Association of Physicists in Medicine, AAPM
    2003 - 2007• Georgia Cancer Coalition Distinguished Scholar Award, Georgia Cancer Coalition and Emory University
    2008Farrington Daniels Award for the best paper on radiation dosimetry - Co-author, Mentor, American Association of Physicists in Medicine
    2009Reviewer with Distinction, Radiology
    2012Fellow of The American College of Radiology, American College of Radiology
    2014Excellence in Peer Review for Year 2013, Academic Radiology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Karellas A. Challenges in Dosimetry and Radiation Dose Trends. Radiology. 2019 Nov 26; 192414. PMID: 31770079.
      View in: PubMed
    2. Deng L, Yasar S, Ahmed MF, Jayarathna S, Feng P, Wei B, Vedantham S, Karellas A, Cho SH. Investigation of transmission computed tomography (CT) image quality and x-ray dose achievable from an experimental dual-mode benchtop x-ray fluorescence CT and transmission CT system. J Xray Sci Technol. 2019 Mar 21. PMID: 30909268.
      View in: PubMed
    3. Shi L, Vedantham S, Karellas A, Zhu L. The role of off-focus radiation in scatter correction for dedicated cone beam breast CT. Med Phys. 2018 Jan; 45(1):191-201. PMID: 29159941.
      View in: PubMed
    4. Vedantham S, Karellas A. Emerging Breast Imaging Technologies on the Horizon. Semin Ultrasound CT MR. 2018 Feb; 39(1):114-121. PMID: 29317033.
      View in: PubMed
    5. O'Connell AM, Karellas A, Vedantham S, Kawakyu-O'Connor DT. Newer Technologies in Breast Cancer Imaging: Dedicated Cone-Beam Breast Computed Tomography. Semin Ultrasound CT MR. 2018 Feb; 39(1):106-113. PMID: 29317032.
      View in: PubMed
    6. Shi L, Vedantham S, Karellas A, Zhu L. X-ray scatter correction for dedicated cone beam breast CT using a forward projection model. Med Phys. 2017 Mar 15. PMID: 28295375.
      View in: PubMed
    7. Shrestha S, Vedantham S, Karellas A. Towards standardization of x-ray beam filters in digital mammography and digital breast tomosynthesis: Monte Carlo simulations and analytical modelling. Phys Med Biol. 2017 Jan 11. PMID: 28075335.
      View in: PubMed
    8. Michaelsen KE, Krishnaswamy V, Shi L, Vedantham S, Karellas A, Pogue BW, Paulsen KD, Poplack SP. Effects of breast density and compression on normal breast tissue hemodynamics through breast tomosynthesis guided near-infrared spectral tomography. J Biomed Opt. 2016 Sep 01; 21(9):91316. PMID: 27677170.
      View in: PubMed
    9. Shi L, Vedantham S, Karellas A, Zhu L. Library based x-ray scatter correction for dedicated cone beam breast CT. Med Phys. 2016 Aug; 43(8):4529. PMID: 27487870.
      View in: PubMed
    10. Vedantham S, Shrestha S, Karellas A, Shi L, Gounis MJ, Bellazzini R, Spandre G, Brez A, Minuti M. Photon-counting hexagonal pixel array CdTe detector: Spatial resolution characteristics for image-guided interventional applications. Med Phys. 2016 May; 43(5):2118. PMID: 27147324.
      View in: PubMed
    11. Zygmanski P, Shrestha S, Briovio D, Karellas A, Sajo E. Prototypes of self-powered radiation detectors employing intrinsic high-energy current. Med Phys. 2016 Jan; 43(1):16. PMID: 26745895.
      View in: PubMed
    12. Vedantham S, Karellas A, Vijayaraghavan GR, Kopans DB. Digital Breast Tomosynthesis: State of the Art. Radiology. 2015 Dec; 277(3):663-84. PMID: 26599926.
      View in: PubMed
    13. Michaelsen KE, Krishnaswamy V, Shi L, Vedantham S, Poplack SP, Karellas A, Pogue BW, Paulsen KD. Calibration and optimization of 3D digital breast tomosynthesis guided near infrared spectral tomography. Biomed Opt Express. 2015 Dec 1; 6(12):4981-91. PMID: 26713210.
      View in: PubMed
    14. Vedantham S, Shi L, Michaelsen KE, Krishnaswamy V, Pogue BW, Poplack SP, Karellas A, Paulsen KD. Digital Breast Tomosynthesis guided Near Infrared Spectroscopy: Volumetric estimates of fibroglandular fraction and breast density from tomosynthesis reconstructions. Biomed Phys Eng Express. 2015; 1(4). PMID: 26941961.
      View in: PubMed
    15. Goertz L, Tsiamas P, Karellas A, Sajo E, Zygmanski P. Monte Carlo simulation of a prototypical patient dosimetry system for fluoroscopic procedures. Phys Med Biol. 2015 Aug 7; 60(15):5891-909. PMID: 26184743.
      View in: PubMed
    16. Elshahat B, Gill HS, Filipyev I, Shrestha S, Hesser J, Kumar J, Karellas A, Zygmanski P, Sajo E. Technical Note: Nanometric organic photovoltaic thin film detectors for dose monitoring in diagnostic x-ray imaging. Med Phys. 2015 Jul; 42(7):4027-32. PMID: 26133603.
      View in: PubMed
    17. Noo F, Karellas A. Introduction: Advances and trends in image formation in X-ray computed tomography. Med Phys. 2015 May; 42(5):2656. PMID: 25979061.
      View in: PubMed
    18. Zygmanski P, Shrestha S, Elshahat B, Karellas A, Sajo E. Dosimetric properties of high energy current (HEC) detector in keV x-ray beams. Phys Med Biol. 2015 Apr 7; 60(7):N121-9. PMID: 25789488.
      View in: PubMed
    19. Vedantham S, O'Connell AM, Shi L, Karellas A, Huston AJ, Skinner KA. Dedicated Breast CT: Feasibility for Monitoring Neoadjuvant Chemotherapy Treatment. J Clin Imaging Sci. 2014; 4:64. PMID: 25558431.
      View in: PubMed
    20. Vedantham S, Shi L, Karellas A. Large-angle x-ray scatter in Talbot-Lau interferometry for breast imaging. Phys Med Biol. 2014 Nov 7; 59(21):6387-400. PMID: 25295630.
      View in: PubMed
    21. O'Connell AM, Karellas A, Vedantham S. The potential role of dedicated 3D breast CT as a diagnostic tool: review and early clinical examples. Breast J. 2014 Nov-Dec; 20(6):592-605. PMID: 25199995.
      View in: PubMed
    22. Jon AF, Cheema AR, Khan AN, Raptopoulos V, Hauser T, Nasser I, Welty FK, Karellas A, Clouse ME. Assessment of liver fat in an obese patient population using noncontrast CT fat percent index. Clin Imaging. 2014 May-Jun; 38(3):259-64. PMID: 24559751.
      View in: PubMed
    23. Marya N, Karellas A, Foley A, Roychowdhury A, Cave D. Computerized 3-dimensional localization of a video capsule in the abdominal cavity: validation by digital radiography. Gastrointest Endosc. 2014 Apr; 79(4):669-74. PMID: 24424401.
      View in: PubMed
    24. Vedantham S, Shi L, Karellas A, O'Connell AM, Conover DL. Personalized estimates of radiation dose from dedicated breast CT in a diagnostic population and comparison with diagnostic mammography. Phys Med Biol. 2013 Nov 21; 58(22):7921-36. PMID: 24165162.
      View in: PubMed
    25. St Peter B, Yngvesson S, Siqueira P, Kelly P, Khan A, Glick S, Karellas A. Development and testing of a single frequency terahertz imaging system for breast cancer detection. IEEE J Biomed Health Inform. 2013 Jul; 17(4):785-97. PMID: 25055306.
      View in: PubMed
    26. Vedantham S, Karellas A, Emmons MM, Moss LJ, Hussain S, Baker SP. Dedicated breast CT: geometric design considerations to maximize posterior breast coverage. Phys Med Biol. 2013 Jun 21; 58(12):4099-118. PMID: 23685899.
      View in: PubMed
    27. Vedantham S, Karellas A. X-ray phase contrast imaging of the breast: analysis of tissue simulating materials. Med Phys. 2013 Apr; 40(4):041906. PMID: 23556900.
      View in: PubMed
    28. Shi L, Vedantham S, Karellas A, O'Connell AM. Technical note: Skin thickness measurements using high-resolution flat-panel cone-beam dedicated breast CT. Med Phys. 2013 Mar; 40(3):031913. PMID: 23464328.
      View in: PubMed
    29. Noo F, Karellas A. Focus series introduction. X-ray computed tomography: 2012 advances in image formation. Med Phys. 2013 Mar; 40(3):031001. PMID: 23464280.
      View in: PubMed
    30. Lange J, Karellas A, Street J, Eck JC, Lapinsky A, Connolly PJ, Dipaola CP. Estimating the effective radiation dose imparted to patients by intraoperative cone-beam computed tomography in thoracolumbar spinal surgery. Spine (Phila Pa 1976). 2013 Mar 1; 38(5):E306-12. PMID: 23238490.
      View in: PubMed
    31. Kanal KM, Krupinski E, Berns EA, Geiser WR, Karellas A, Mainiero MB, Martin MC, Patel SB, Rubin DL, Shepard JD, Siegel EL, Wolfman JA, Mian TA, Mahoney MC. ACR-AAPM-SIIM practice guideline for determinants of image quality in digital mammography. J Digit Imaging. 2013 Feb; 26(1):10-25. PMID: 22992865.
      View in: PubMed
    32. Vedantham S, Shi L, Glick SJ, Karellas A. Scaling-law for the energy dependence of anatomic power spectrum in dedicated breast CT. Med Phys. 2013 Jan; 40(1):011901. PMID: 23298092.
      View in: PubMed
    33. Vedantham S, Shi L, Karellas A, O'Connell AM. Dedicated breast CT: fibroglandular volume measurements in a diagnostic population. Med Phys. 2012 Dec; 39(12):7317-28. PMID: 23231281.
      View in: PubMed
    34. D'Orsi CJ, Getty DJ, Pickett RM, Sechopoulos I, Newell MS, Gundry KR, Bates SR, Nishikawa RM, Sickles EA, Karellas A, D'Orsi EM. Stereoscopic digital mammography: improved specificity and reduced rate of recall in a prospective clinical trial. Radiology. 2013 Jan; 266(1):81-8. PMID: 23150865.
      View in: PubMed
    35. Jones BL, Manohar N, Reynoso F, Karellas A, Cho SH. Experimental demonstration of benchtop x-ray fluorescence computed tomography (XFCT) of gold nanoparticle-loaded objects using lead- and tin-filtered polychromatic cone-beams. Phys Med Biol. 2012 Dec 7; 57(23):N457-67. PMID: 23135315.
      View in: PubMed
    36. Karellas A. Photon-counting digital mammography: evaluation of performance under clinically relevant conditions. Acad Radiol. 2012 Aug; 19(8):913-5. PMID: 22770464.
      View in: PubMed
    37. Vedantham S, Shi L, Karellas A, Noo F. Dedicated breast CT: radiation dose for circle-plus-line trajectory. Med Phys. 2012 Mar; 39(3):1530-41. PMID: 22380385.
      View in: PubMed
    38. Yngvesson SK, St Peter B, Siqueira P, Kelly P, Glick S, Karellas A, Khan A. Feasibility demonstration of frequency domain terahertz imaging in breast cancer margin determination. Proc SPIE Int Soc Opt Eng. 2012 Feb 9; 8221. PMID: 24353380.
      View in: PubMed
    39. Noo F, Karellas A. X-ray computed tomography: advances in image formation. Med Phys. 2011 Jul; 38 Suppl 1:S1. PMID: 21978110.
      View in: PubMed
    40. Vedantham S, Shi L, Karellas A, Michaelsen KE, Krishnaswamy V, Pogue BW, Paulsen KD. Semi-automated segmentation and classification of digital breast tomosynthesis reconstructed images. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:6188-91. PMID: 22255752.
      View in: PubMed
    41. Vedantham S, Karellas A. Modeling the performance characteristics of computed radiography (CR) systems. IEEE Trans Med Imaging. 2010 Mar; 29(3):790-806. PMID: 20199915.
      View in: PubMed
    42. Karathanasis E, Suryanarayanan S, Balusu SR, McNeeley K, Sechopoulos I, Karellas A, Annapragada AV, Bellamkonda RV. Imaging nanoprobe for prediction of outcome of nanoparticle chemotherapy by using mammography. Radiology. 2009 Feb; 250(2):398-406. PMID: 19188313.
      View in: PubMed
    43. Karellas A, Vedantham S. Breast cancer imaging: a perspective for the next decade. Med Phys. 2008 Nov; 35(11):4878-97. PMID: 19070222.
      View in: PubMed
    44. Sechopoulos I, Vedantham S, Suryanarayanan S, D'Orsi CJ, Karellas A. Monte Carlo and phantom study of the radiation dose to the body from dedicated CT of the breast. Radiology. 2008 Apr; 247(1):98-105. PMID: 18292479.
      View in: PubMed
    45. Karellas A, Lo JY, Orton CG. Point/Counterpoint. Cone beam x-ray CT will be superior to digital x-ray tomosynthesis in imaging the breast and delineating cancer. Med Phys. 2008 Feb; 35(2):409-11. PMID: 18383660.
      View in: PubMed
    46. Sechopoulos I, Suryanarayanan S, Vedantham S, D'Orsi CJ, Karellas A. Radiation dose to organs and tissues from mammography: Monte Carlo and phantom study. Radiology. 2008 Feb; 246(2):434-43. PMID: 18056857.
      View in: PubMed
    47. Sechopoulos I, Suryanarayanan S, Vedantham S, D'Orsi CJ, Karellas A. Erratum: "Scatter radiation in digital tomosynthesis of the breast" [Med. Phys., - (2007)]. Med Phys. 2007 Sep; 34(9):3697. PMID: 28524954.
      View in: PubMed
    48. Suryanarayanan S, Karellas A, Vedantham S, Sechopoulos I, D'Orsi CJ. Detection of simulated microcalcifications in a phantom with digital mammography: effect of pixel size. Radiology. 2007 Jul; 244(1):130-7. PMID: 17522348.
      View in: PubMed
    49. Karellas A. Mammographic pattern analysis: an emerging risk assessment tool. Acad Radiol. 2007 May; 14(5):511-2. PMID: 17434063.
      View in: PubMed
    50. Sechopoulos I, Suryanarayanan S, Vedantham S, D'Orsi CJ, Karellas A. Scatter radiation in digital tomosynthesis of the breast. Med Phys. 2007 Feb; 34(2):564-76. PMID: 17388174.
      View in: PubMed
    51. Sechopoulos I, Suryanarayanan S, Vedantham S, D'Orsi C, Karellas A. Computation of the glandular radiation dose in digital tomosynthesis of the breast. Med Phys. 2007 Jan; 34(1):221-32. PMID: 17278508.
      View in: PubMed
    52. Suryanarayanan S, Karellas A, Vedantham S, Sechopoulos I. Theoretical analysis of high-resolution digital mammography. Phys Med Biol. 2006 Jun 21; 51(12):3041-55. PMID: 16757861.
      View in: PubMed
    53. Suryanarayanan S, Karellas A, Vedantham S, Onishi SK. High-resolution imager for digital mammography: physical characterization of a prototype sensor. Phys Med Biol. 2005 Sep 7; 50(17):3957-69. PMID: 16177523.
      View in: PubMed
    54. Suryanarayanan S, Karellas A, Vedantham S, Waldrop SM, D'Orsi CJ. Detection of simulated lesions on data-compressed digital mammograms. Radiology. 2005 Jul; 236(1):31-6. PMID: 15983071.
      View in: PubMed
    55. Vedantham S, Karellas A, Suryanarayanan S, Onishi SK. Solid-state fluoroscopic imager for high-resolution angiography: physical characteristics of an 8 cm x 8 cm experimental prototype. Med Phys. 2004 Jun; 31(6):1462-72. PMID: 15259649.
      View in: PubMed
    56. Vedantham S, Karellas A, Suryanarayanan S. Solid-state fluoroscopic imager for high-resolution angiography: parallel-cascaded linear systems analysis. Med Phys. 2004 May; 31(5):1258-68. PMID: 15191318.
      View in: PubMed
    57. Suryanarayanan S, Karellas A, Vedantham S, Waldrop SM, D'Orsi CJ. A perceptual evaluation of JPEG 2000 image compression for digital mammography: contrast-detail characteristics. J Digit Imaging. 2004 Mar; 17(1):64-70. PMID: 15255520.
      View in: PubMed
    58. Suryanarayanan S, Karellas A, Vedantham S, Ved H, Baker SP, D'Orsi CJ. Flat-panel digital mammography system: contrast-detail comparison between screen-film radiographs and hard-copy images. Radiology. 2002 Dec; 225(3):801-7. PMID: 12461264.
      View in: PubMed
    59. Lewin JM, D'Orsi CJ, Hendrick RE, Moss LJ, Isaacs PK, Karellas A, Cutter GR. Clinical comparison of full-field digital mammography and screen-film mammography for detection of breast cancer. AJR Am J Roentgenol. 2002 Sep; 179(3):671-7. PMID: 12185042.
      View in: PubMed
    60. Kleinman PK, O'Connor B, Nimkin K, Rayder SM, Spevak MR, Belanger PL, Getty DJ, Karellas A. Detection of rib fractures in an abused infant using digital radiography: a laboratory study. Pediatr Radiol. 2002 Dec; 32(12):896-901. PMID: 12447601.
      View in: PubMed
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