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Connection

Sharon Cantor to DNA Repair

This is a "connection" page, showing publications Sharon Cantor has written about DNA Repair.
Connection Strength

4.406
  1. Cong K, Cantor SB. Exploiting replication gaps for cancer therapy. Mol Cell. 2022 07 07; 82(13):2363-2369.
    View in: PubMed
    Score: 0.687
  2. Cantor S. TPX2 joins 53BP1 to maintain DNA repair and fork stability. J Cell Biol. 2019 02 04; 218(2):383-384.
    View in: PubMed
    Score: 0.545
  3. Cantor SB, Brosh RM. What is wrong with Fanconi anemia cells? Cell Cycle. 2014; 13(24):3823-7.
    View in: PubMed
    Score: 0.385
  4. Cantor SB, Xie J. Assessing the link between BACH1/FANCJ and MLH1 in DNA crosslink repair. Environ Mol Mutagen. 2010 Jul; 51(6):500-7.
    View in: PubMed
    Score: 0.302
  5. Xie J, Litman R, Wang S, Peng M, Guillemette S, Rooney T, Cantor SB. Targeting the FANCJ-BRCA1 interaction promotes a switch from recombination to poleta-dependent bypass. Oncogene. 2010 Apr 29; 29(17):2499-508.
    View in: PubMed
    Score: 0.294
  6. Litman R, Gupta R, Brosh RM, Cantor SB. BRCA-FA pathway as a target for anti-tumor drugs. Anticancer Agents Med Chem. 2008 May; 8(4):426-30.
    View in: PubMed
    Score: 0.260
  7. Peng M, Litman R, Jin Z, Fong G, Cantor SB. BACH1 is a DNA repair protein supporting BRCA1 damage response. Oncogene. 2006 Apr 06; 25(15):2245-53.
    View in: PubMed
    Score: 0.225
  8. MacGilvary N, Cantor SB. Positioning loss of PARP1 activity as the central toxic event in BRCA-deficient cancer. DNA Repair (Amst). 2024 Dec; 144:103775.
    View in: PubMed
    Score: 0.203
  9. Cong K, MacGilvary N, Lee S, MacLeod SG, Calvo J, Peng M, Nedergaard Kousholt A, Day TA, Cantor SB. FANCJ promotes PARP1 activity during DNA replication that is essential in BRCA1 deficient cells. Nat Commun. 2024 Mar 23; 15(1):2599.
    View in: PubMed
    Score: 0.195
  10. Whalen JM, Cantor SB. Unveiling the toxicity of single-stranded DNA gaps through a yeast model. Nat Struct Mol Biol. 2023 07; 30(7):870-872.
    View in: PubMed
    Score: 0.186
  11. Cantor SB. Revisiting the BRCA-pathway through the lens of replication gap suppression: "Gaps determine therapy response in BRCA mutant cancer". DNA Repair (Amst). 2021 Nov; 107:103209.
    View in: PubMed
    Score: 0.163
  12. Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM. BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cell. 2001 Apr 06; 105(1):149-60.
    View in: PubMed
    Score: 0.159
  13. Panzarino NJ, Krais JJ, Cong K, Peng M, Mosqueda M, Nayak SU, Bond SM, Calvo JA, Doshi MB, Bere M, Ou J, Deng B, Zhu LJ, Johnson N, Cantor SB. Replication Gaps Underlie BRCA Deficiency and Therapy Response. Cancer Res. 2021 03 01; 81(5):1388-1397.
    View in: PubMed
    Score: 0.155
  14. Cantor SB, Nayak S. FANCJ at the FORK. Mutat Res. 2016 06; 788:7-11.
    View in: PubMed
    Score: 0.111
  15. Guillemette S, Branagan A, Peng M, Dhruva A, Sch?rer OD, Cantor SB. FANCJ localization by mismatch repair is vital to maintain genomic integrity after UV irradiation. Cancer Res. 2014 Feb 01; 74(3):932-44.
    View in: PubMed
    Score: 0.096
  16. Suhasini AN, Sommers JA, Muniandy PA, Coulombe Y, Cantor SB, Masson JY, Seidman MM, Brosh RM. Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response. Mol Cell Biol. 2013 Jun; 33(11):2212-27.
    View in: PubMed
    Score: 0.091
  17. Xie J, Peng M, Guillemette S, Quan S, Maniatis S, Wu Y, Venkatesh A, Shaffer SA, Brosh RM, Cantor SB. FANCJ/BACH1 acetylation at lysine 1249 regulates the DNA damage response. PLoS Genet. 2012 Jul; 8(7):e1002786.
    View in: PubMed
    Score: 0.087
  18. Cantor SB, Guillemette S. Hereditary breast cancer and the BRCA1-associated FANCJ/BACH1/BRIP1. Future Oncol. 2011 Feb; 7(2):253-61.
    View in: PubMed
    Score: 0.079
  19. Sommers JA, Rawtani N, Gupta R, Bugreev DV, Mazin AV, Cantor SB, Brosh RM. FANCJ uses its motor ATPase to destabilize protein-DNA complexes, unwind triplexes, and inhibit RAD51 strand exchange. J Biol Chem. 2009 Mar 20; 284(12):7505-17.
    View in: PubMed
    Score: 0.068
  20. Awate S, Sommers JA, Datta A, Nayak S, Bellani MA, Yang O, Dunn CA, Nicolae CM, Moldovan GL, Seidman MM, Cantor SB, Brosh RM. FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links. Nucleic Acids Res. 2020 09 18; 48(16):9161-9180.
    View in: PubMed
    Score: 0.038
  21. Ray Chaudhuri A, Callen E, Ding X, Gogola E, Duarte AA, Lee JE, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, de Ruiter JR, Daniel JA, Konstantinopoulos PA, Cortez D, Cantor SB, Fernandez-Capetillo O, Ge K, Jonkers J, Rottenberg S, Sharan SK, Nussenzweig A. Replication fork stability confers chemoresistance in BRCA-deficient cells. Nature. 2016 07 21; 535(7612):382-7.
    View in: PubMed
    Score: 0.029
  22. Barber LJ, Youds JL, Ward JD, McIlwraith MJ, O'Neil NJ, Petalcorin MI, Martin JS, Collis SJ, Cantor SB, Auclair M, Tissenbaum H, West SC, Rose AM, Boulton SJ. RTEL1 maintains genomic stability by suppressing homologous recombination. Cell. 2008 Oct 17; 135(2):261-71.
    View in: PubMed
    Score: 0.017
  23. Greenberg RA, Sobhian B, Pathania S, Cantor SB, Nakatani Y, Livingston DM. Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes. Genes Dev. 2006 Jan 01; 20(1):34-46.
    View in: PubMed
    Score: 0.014
  24. Chen JJ, Silver D, Cantor S, Livingston DM, Scully R. BRCA1, BRCA2, and Rad51 operate in a common DNA damage response pathway. Cancer Res. 1999 Apr 01; 59(7 Suppl):1752s-1756s.
    View in: PubMed
    Score: 0.009
  25. Chen J, Silver DP, Walpita D, Cantor SB, Gazdar AF, Tomlinson G, Couch FJ, Weber BL, Ashley T, Livingston DM, Scully R. Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells. Mol Cell. 1998 Sep; 2(3):317-28.
    View in: PubMed
    Score: 0.008
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.