Cole Haynes to Caenorhabditis elegans Proteins
This is a "connection" page, showing publications Cole Haynes has written about Caenorhabditis elegans Proteins.
Connection Strength
5.718
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Uma Naresh N, Kim S, Shpilka T, Yang Q, Du Y, Haynes CM. Mitochondrial genome recovery by ATFS-1 is essential for development after starvation. Cell Rep. 2022 12 27; 41(13):111875.
Score: 0.573
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Haynes CM, Hekimi S. Mitochondrial dysfunction, aging, and the mitochondrial unfolded protein response in Caenorhabditis elegans. Genetics. 2022 11 30; 222(4).
Score: 0.570
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Yang Q, Liu P, Anderson NS, Shpilka T, Du Y, Naresh NU, Li R, Zhu LJ, Luk K, Lavelle J, Zeinert RD, Chien P, Wolfe SA, Haynes CM. LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria. Nat Cell Biol. 2022 02; 24(2):181-193.
Score: 0.540
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Shpilka T, Du Y, Yang Q, Melber A, Uma Naresh N, Lavelle J, Kim S, Liu P, Weidberg H, Li R, Yu J, Zhu LJ, Strittmatter L, Haynes CM. UPRmt scales mitochondrial network expansion with protein synthesis via mitochondrial import in Caenorhabditis elegans. Nat Commun. 2021 01 20; 12(1):479.
Score: 0.501
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Ali L, Haynes CM. Mitochondrial translation, dynamics, and lysosomes combine to extend lifespan. J Cell Biol. 2020 06 01; 219(6).
Score: 0.480
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Deng P, Uma Naresh N, Du Y, Lamech LT, Yu J, Zhu LJ, Pukkila-Worley R, Haynes CM. Mitochondrial UPR repression during Pseudomonas aeruginosa infection requires the bZIP protein ZIP-3. Proc Natl Acad Sci U S A. 2019 03 26; 116(13):6146-6151.
Score: 0.440
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Nargund AM, Fiorese CJ, Pellegrino MW, Deng P, Haynes CM. Mitochondrial and nuclear accumulation of the transcription factor ATFS-1 promotes OXPHOS recovery during the UPR(mt). Mol Cell. 2015 Apr 02; 58(1):123-33.
Score: 0.334
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Nargund AM, Pellegrino MW, Fiorese CJ, Baker BM, Haynes CM. Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation. Science. 2012 Aug 03; 337(6094):587-90.
Score: 0.276
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Baker BM, Nargund AM, Sun T, Haynes CM. Protective coupling of mitochondrial function and protein synthesis via the eIF2a kinase GCN-2. PLoS Genet. 2012; 8(6):e1002760.
Score: 0.276
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Haynes CM, Yang Y, Blais SP, Neubert TA, Ron D. The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans. Mol Cell. 2010 Feb 26; 37(4):529-40.
Score: 0.235
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Haynes CM, Petrova K, Benedetti C, Yang Y, Ron D. ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans. Dev Cell. 2007 Oct; 13(4):467-80.
Score: 0.199
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Lee YU, Fox BW, Guo R, Curtis BJ, Yu J, Kim S, Nanda S, Baumann V, Yilmaz LS, Haynes CM, Schroeder FC, Walhout AJM. Host-microbe interactions rewire metabolism in a C.?elegans model of leucine breakdown deficiency. Nat Metab. 2024 Aug; 6(8):1584-1600.
Score: 0.160
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Dai CY, Ng CC, Hung GCC, Kirmes I, Hughes LA, Du Y, Brosnan CA, Ahier A, Hahn A, Haynes CM, Rackham O, Filipovska A, Zuryn S. ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription. Nat Cell Biol. 2023 08; 25(8):1111-1120.
Score: 0.149
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Statzer C, Meng J, Venz R, Bland M, Robida-Stubbs S, Patel K, Petrovic D, Emsley R, Liu P, Morantte I, Haynes C, Mair WB, Longchamp A, Filipovic MR, Blackwell TK, Ewald CY. ATF-4 and hydrogen sulfide signalling mediate longevity in response to inhibition of translation or mTORC1. Nat Commun. 2022 02 18; 13(1):967.
Score: 0.135
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Nhan JD, Turner CD, Anderson SM, Yen CA, Dalton HM, Cheesman HK, Ruter DL, Uma Naresh N, Haynes CM, Soukas AA, Pukkila-Worley R, Curran SP. Redirection of SKN-1 abates the negative metabolic outcomes of a perceived pathogen infection. Proc Natl Acad Sci U S A. 2019 10 29; 116(44):22322-22330.
Score: 0.115
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Peterson ND, Cheesman HK, Liu P, Anderson SM, Foster KJ, Chhaya R, Perrat P, Thekkiniath J, Yang Q, Haynes CM, Pukkila-Worley R. The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegans. PLoS Genet. 2019 01; 15(1):e1007935.
Score: 0.109
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Fiorese CJ, Schulz AM, Lin YF, Rosin N, Pellegrino MW, Haynes CM. The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR. Curr Biol. 2016 08 08; 26(15):2037-2043.
Score: 0.092
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Lin YF, Schulz AM, Pellegrino MW, Lu Y, Shaham S, Haynes CM. Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response. Nature. 2016 05 19; 533(7603):416-9.
Score: 0.090
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Reddy KC, Dunbar TL, Nargund AM, Haynes CM, Troemel ER. The C.?elegans CCAAT-Enhancer-Binding Protein Gamma Is Required for Surveillance Immunity. Cell Rep. 2016 Feb 23; 14(7):1581-1589.
Score: 0.089
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Haynes C, Powell K. Cole Haynes: on the trail of mitochondrial dysfunction. J Cell Biol. 2015 Jan 19; 208(2):140-1.
Score: 0.083
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Pellegrino MW, Nargund AM, Kirienko NV, Gillis R, Fiorese CJ, Haynes CM. Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection. Nature. 2014 Dec 18; 516(7531):414-7.
Score: 0.081
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Pellegrino MW, Nargund AM, Haynes CM. Signaling the mitochondrial unfolded protein response. Biochim Biophys Acta. 2013 Feb; 1833(2):410-6.
Score: 0.068
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Haynes CM, Ron D. The mitochondrial UPR - protecting organelle protein homeostasis. J Cell Sci. 2010 Nov 15; 123(Pt 22):3849-55.
Score: 0.062
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Labbadia J, Brielmann RM, Neto MF, Lin YF, Haynes CM, Morimoto RI. Mitochondrial Stress Restores the Heat Shock Response and Prevents Proteostasis Collapse during Aging. Cell Rep. 2017 Nov 07; 21(6):1481-1494.
Score: 0.025
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Yun C, Stanhill A, Yang Y, Zhang Y, Haynes CM, Xu CF, Neubert TA, Mor A, Philips MR, Ron D. Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2008 May 13; 105(19):7094-9.
Score: 0.013
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Stanhill A, Haynes CM, Zhang Y, Min G, Steele MC, Kalinina J, Martinez E, Pickart CM, Kong XP, Ron D. An arsenite-inducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity. Mol Cell. 2006 Sep 15; 23(6):875-85.
Score: 0.012
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Benedetti C, Haynes CM, Yang Y, Harding HP, Ron D. Ubiquitin-like protein 5 positively regulates chaperone gene expression in the mitochondrial unfolded protein response. Genetics. 2006 Sep; 174(1):229-39.
Score: 0.011