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Mahasweta Girgenrath PhD

TitleAssociate Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentNeurology
AddressUniversity of Massachusetts Medical School
55 Lake Avenue North
Worcester MA 01655
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentNeurology


    Collapse Biography 
    Collapse education and training
    Annamalai University, Chidambaram, TN, IndiaBEDBiology & English
    Delhi University, New Delhi, DL, IndiaBSBiology
    Northeastern University, Boston, MA, United StatesPHDBiology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Gordish-Dressman H, Willmann R, Pazze LD, Kreibich A, van Putten M, Heydemann A, Bogdanik L, Lutz C, Davies K, Demonbruen AR, Duan D, Elsey D, Fukada SI, Girgenrath M, Gonzalez JP, Grounds MD, Nichols A, Partridge T, Passini M, Sanarica F, Schnell FJ, Wells DJ, Yokota T, Young CS, Zhong Z, Spurney C, Spencer M, De Luca A, Nagaraju K, Aartsma-Rus A. "Of Mice and Measures": A Project to Improve How We Advance Duchenne Muscular Dystrophy Therapies to the Clinic First Workshop Report: Examining current findings and opportunities around the emerging D2.B10-Dmdmdx/J (D2/mdx) model in context of the classic C57BL/10ScSn-Dmdmdx/J (Bl10/mdx). J Neuromuscul Dis. 2018 Sep 03. PMID: 30198876.
      View in: PubMed
    2. Willmann R, Gordish-Dressman H, Meinen S, Rüegg MA, Yu Q, Nagaraju K, Kumar A, Girgenrath M, Coffey CBM, Cruz V, Van Ry PM, Bogdanik L, Lutz C, Rutkowski A, Burkin DJ. Improving Reproducibility of Phenotypic Assessments in the DyW Mouse Model of Laminin-a2 Related Congenital Muscular Dystrophy. J Neuromuscul Dis. 2017 May 24. PMID: 28550268.
      View in: PubMed
    3. Accorsi A, Kumar A, Rhee Y, Miller A, Girgenrath M. IGF-1/GH axis enhances losartan treatment in Lama2-related muscular dystrophy. Hum Mol Genet. 2016 Oct 24. PMID: 27798092.
      View in: PubMed
    4. Clark AL, Maruyama S, Sano S, Accorsi A, Girgenrath M, Walsh K, Naya FJ. miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy. PLoS One. 2016; 11(3):e0151515. PMID: 26999812.
      View in: PubMed
    5. Vohra R, Accorsi A, Kumar A, Walter G, Girgenrath M. Magnetic Resonance Imaging Is Sensitive to Pathological Amelioration in a Model for Laminin-Deficient Congenital Muscular Dystrophy (MDC1A). PLoS One. 2015; 10(9):e0138254. PMID: 26379183.
      View in: PubMed
    6. Kumar A, Accorsi A, Rhee Y, Girgenrath M. Do's and don'ts in the preparation of muscle cryosections for histological analysis. J Vis Exp. 2015; (99):e52793. PMID: 26066009.
      View in: PubMed
    7. Accorsi A, Mehuron T, Kumar A, Rhee Y, Girgenrath M. Integrin dysregulation as a possible driver of matrix remodeling in Laminin-deficient congenital muscular dystrophy (MDC1A). J Neuromuscul Dis. 2015; 2(1):51-61. PMID: 28198706.
      View in: PubMed
    8. Mehuron T, Kumar A, Duarte L, Yamauchi J, Accorsi A, Girgenrath M. Dysregulation of matricellular proteins is an early signature of pathology in laminin-deficient muscular dystrophy. Skelet Muscle. 2014; 4:14. PMID: 25075272.
      View in: PubMed
    9. Yamauchi J, Kumar A, Duarte L, Mehuron T, Girgenrath M. Triggering regeneration and tackling apoptosis: a combinatorial approach to treating congenital muscular dystrophy type 1 A. Hum Mol Genet. 2013 Nov 1; 22(21):4306-17. PMID: 23773998.
      View in: PubMed
    10. Rutkowski A, Bönnemann C, Brown S, Thorsteinsdóttir S, Dominov J, Ruegg MA, Matter ML, Guttridge D, Crosbie-Watson RH, Kardon G, Nagaraju K, Girgenrath M, Burkin DJ. Report on the Myomatrix Conference April 22-24, 2012, University of Nevada, Reno, Nevada, USA. Neuromuscul Disord. 2013 Feb; 23(2):188-91. PMID: 22800409.
      View in: PubMed
    11. Kumar A, Yamauchi J, Girgenrath T, Girgenrath M. Muscle-specific expression of insulin-like growth factor 1 improves outcome in Lama2Dy-w mice, a model for congenital muscular dystrophy type 1A. Hum Mol Genet. 2011 Jun 15; 20(12):2333-43. PMID: 21441569.
      View in: PubMed
    12. Beermann ML, Ardelt M, Girgenrath M, Miller JB. Prdm1 (Blimp-1) and the expression of fast and slow myosin heavy chain isoforms during avian myogenesis in vitro. PLoS One. 2010 Apr 01; 5(4):e9951. PMID: 20376350.
      View in: PubMed
    13. Girgenrath M, Beermann ML, Vishnudas VK, Homma S, Miller JB. Pathology is alleviated by doxycycline in a laminin-alpha2-null model of congenital muscular dystrophy. Ann Neurol. 2009 Jan; 65(1):47-56. PMID: 19086074.
      View in: PubMed
    14. Girgenrath M, Weng S, Kostek CA, Browning B, Wang M, Brown SA, Winkles JA, Michaelson JS, Allaire N, Schneider P, Scott ML, Hsu YM, Yagita H, Flavell RA, Miller JB, Burkly LC, Zheng TS. TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration. EMBO J. 2006 Dec 13; 25(24):5826-39. PMID: 17124496.
      View in: PubMed
    15. Miller JB, Girgenrath M. The role of apoptosis in neuromuscular diseases and prospects for anti-apoptosis therapy. Trends Mol Med. 2006 Jun; 12(6):279-86. PMID: 16650805.
      View in: PubMed
    16. Girgenrath M, Kostek CA, Miller JB. Diseased muscles that lack dystrophin or laminin-alpha2 have altered compositions and proliferation of mononuclear cell populations. BMC Neurol. 2005 Apr 07; 5(1):7. PMID: 15817132.
      View in: PubMed
    17. Girgenrath M, Dominov JA, Kostek CA, Miller JB. Inhibition of apoptosis improves outcome in a model of congenital muscular dystrophy. J Clin Invest. 2004 Dec; 114(11):1635-9. PMID: 15578095.
      View in: PubMed
    18. Nowak JA, Malowitz J, Girgenrath M, Kostek CA, Kravetz AJ, Dominov JA, Miller JB. Immortalization of mouse myogenic cells can occur without loss of p16INK4a, p19ARF, or p53 and is accelerated by inactivation of Bax. BMC Cell Biol. 2004 Jan 08; 5:1. PMID: 14711384.
      View in: PubMed
    19. Girgenrath M, Marsh RL. Season and testosterone affect contractile properties of fast calling muscles in the gray tree frog Hyla chrysoscelis. Am J Physiol Regul Integr Comp Physiol. 2003 Jun; 284(6):R1513-20. PMID: 12595277.
      View in: PubMed
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