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Mahasweta Girgenrath PhD

TitleAssociate Professor
InstitutionUMass Chan Medical School
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
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    Other Positions
    InstitutionT.H. Chan School of Medicine

    Collapse Biography 
    Collapse education and training
    Annamalai University, Chidambaram, TN, IndiaBEDBiology & English
    Delhi University, New Delhi, DL, IndiaBSBiology
    Northeastern University, Boston, MA, United StatesPHDBiology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Accorsi A, Cramer ML, Girgenrath M. Fibrogenesis in LAMA2-Related Muscular Dystrophy Is a Central Tenet of Disease Etiology. Front Mol Neurosci. 2020; 13:3. PMID: 32116541.
    2. Gordish-Dressman H, Willmann R, Dalle Pazze L, Kreibich A, van Putten M, Heydemann A, Bogdanik L, Lutz C, Davies K, Demonbreun AR, Duan D, Elsey D, Fukada SI, Girgenrath M, Patrick Gonzalez J, Grounds MD, Nichols A, Partridge T, Passini M, Sanarica F, Schnell FJ, Wells DJ, Yokota T, Young CS, Zhong Z, Spurney C, Spencer M, De Luca A, Nagaraju K, Aartsma-Rus A. "Of Mice and Measures": A Project to Improve How We Advance Duchenne Muscular Dystrophy Therapies to the Clinic. J Neuromuscul Dis. 2018; 5(4):407-417. PMID: 30198876.
      Citations: 10     Fields:    Translation:Animals
    3. Willmann R, Gordish-Dressman H, Meinen S, Rüegg MA, Yu Q, Nagaraju K, Kumar A, Girgenrath M, Coffey CBM, Cruz V, Van Ry PM, Bogdanik L, Lutz C, Rutkowski A, Burkin DJ. Improving Reproducibility of Phenotypic Assessments in the DyW Mouse Model of Laminin-?2 Related Congenital Muscular Dystrophy. J Neuromuscul Dis. 2017; 4(2):115-126. PMID: 28550268.
      Citations: 8     Fields:    Translation:Animals
    4. Accorsi A, Kumar A, Rhee Y, Miller A, Girgenrath M. IGF-1/GH axis enhances losartan treatment in Lama2-related muscular dystrophy. Hum Mol Genet. 2016 10 24; 25(21):4624–4634. PMID: 27798092.
      Citations: 16     Fields:    
    5. Clark AL, Maruyama S, Sano S, Accorsi A, Girgenrath M, Walsh K, Naya FJ. miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy. PLoS One. 2016; 11(3):e0151515. PMID: 26999812.
      Citations: 21     Fields:    Translation:AnimalsCells
    6. Vohra R, Accorsi A, Kumar A, Walter G, Girgenrath M. Magnetic Resonance Imaging Is Sensitive to Pathological Amelioration in a Model for Laminin-Deficient Congenital Muscular Dystrophy (MDC1A). PLoS One. 2015; 10(9):e0138254. PMID: 26379183.
      Citations: 8     Fields:    Translation:Animals
    7. Kumar A, Accorsi A, Rhee Y, Girgenrath M. Do's and don'ts in the preparation of muscle cryosections for histological analysis. J Vis Exp. 2015 May 15; (99):e52793. PMID: 26066009.
      Citations: 13     Fields:    Translation:Animals
    8. Accorsi A, Mehuron T, Kumar A, Rhee Y, Girgenrath M. Integrin dysregulation as a possible driver of matrix remodeling in Laminin-deficient congenital muscular dystrophy (MDC1A). J Neuromuscul Dis. 2015; 2(1):51-61. PMID: 28198706.
      Citations: 7     Fields:    
    9. Mehuron T, Kumar A, Duarte L, Yamauchi J, Accorsi A, Girgenrath M. Dysregulation of matricellular proteins is an early signature of pathology in laminin-deficient muscular dystrophy. Skelet Muscle. 2014; 4:14. PMID: 25075272.
      Citations: 15     Fields:    
    10. Yamauchi J, Kumar A, Duarte L, Mehuron T, Girgenrath M. Triggering regeneration and tackling apoptosis: a combinatorial approach to treating congenital muscular dystrophy type 1 A. Hum Mol Genet. 2013 Nov 01; 22(21):4306-17. PMID: 23773998.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    11. Rutkowski A, Bönnemann C, Brown S, Thorsteinsdóttir S, Dominov J, Ruegg MA, Matter ML, Guttridge D, Crosbie-Watson RH, Kardon G, Nagaraju K, Girgenrath M, Burkin DJ. Report on the Myomatrix Conference April 22-24, 2012, University of Nevada, Reno, Nevada, USA. Neuromuscul Disord. 2013 Feb; 23(2):188-91. PMID: 22800409.
      Citations: 1     Fields:    Translation:HumansCells
    12. Kumar A, Yamauchi J, Girgenrath T, Girgenrath M. Muscle-specific expression of insulin-like growth factor 1 improves outcome in Lama2Dy-w mice, a model for congenital muscular dystrophy type 1A. Hum Mol Genet. 2011 Jun 15; 20(12):2333-43. PMID: 21441569.
      Citations: 22     Fields:    Translation:Animals
    13. Beermann ML, Ardelt M, Girgenrath M, Miller JB. Prdm1 (Blimp-1) and the expression of fast and slow myosin heavy chain isoforms during avian myogenesis in vitro. PLoS One. 2010 Apr 01; 5(4):e9951. PMID: 20376350.
      Citations: 6     Fields:    Translation:AnimalsCells
    14. Girgenrath M, Beermann ML, Vishnudas VK, Homma S, Miller JB. Pathology is alleviated by doxycycline in a laminin-alpha2-null model of congenital muscular dystrophy. Ann Neurol. 2009 Jan; 65(1):47-56. PMID: 19086074.
      Citations: 41     Fields:    Translation:AnimalsCells
    15. Girgenrath M, Weng S, Kostek CA, Browning B, Wang M, Brown SA, Winkles JA, Michaelson JS, Allaire N, Schneider P, Scott ML, Hsu YM, Yagita H, Flavell RA, Miller JB, Burkly LC, Zheng TS. TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration. EMBO J. 2006 Dec 13; 25(24):5826-39. PMID: 17124496.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    16. Miller JB, Girgenrath M. The role of apoptosis in neuromuscular diseases and prospects for anti-apoptosis therapy. Trends Mol Med. 2006 Jun; 12(6):279-86. PMID: 16650805.
      Citations: 19     Fields:    Translation:HumansAnimals
    17. Girgenrath M, Kostek CA, Miller JB. Diseased muscles that lack dystrophin or laminin-alpha2 have altered compositions and proliferation of mononuclear cell populations. BMC Neurol. 2005 Apr 07; 5(1):7. PMID: 15817132.
      Citations: 9     Fields:    Translation:AnimalsCells
    18. Girgenrath M, Dominov JA, Kostek CA, Miller JB. Inhibition of apoptosis improves outcome in a model of congenital muscular dystrophy. J Clin Invest. 2004 Dec; 114(11):1635-9. PMID: 15578095.
      Citations: 59     Fields:    Translation:HumansAnimals
    19. Nowak JA, Malowitz J, Girgenrath M, Kostek CA, Kravetz AJ, Dominov JA, Miller JB. Immortalization of mouse myogenic cells can occur without loss of p16INK4a, p19ARF, or p53 and is accelerated by inactivation of Bax. BMC Cell Biol. 2004 Jan 08; 5:1. PMID: 14711384.
      Citations: 9     Fields:    Translation:AnimalsCells
    20. Girgenrath M, Marsh RL. Season and testosterone affect contractile properties of fast calling muscles in the gray tree frog Hyla chrysoscelis. Am J Physiol Regul Integr Comp Physiol. 2003 Jun; 284(6):R1513-20. PMID: 12595277.
      Citations: 4     Fields:    Translation:Animals
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