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Brian Michael Skehan MD, PhD

TitleAssistant Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentPsychiatry
AddressUniversity of Massachusetts Medical School
55 Lake Avenue North
Worcester MA 01655
Phone508-856-2193
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentPediatrics

    InstitutionUMMS - School of Medicine
    DepartmentPsychiatry


    Collapse Biography 
    Collapse education and training
    Sacred Heart University, Fairfield, CT, United StatesBSBiology
    University of Massachusetts Medical School, Worcester, MA, United StatesMD
    University of Massachusetts Medical School, Worcester, MA, United StatesPHDBiomedical Sciences

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Downs N, Galles E, Skehan B, Lipson SK. Be True to Our Schools-Models of Care in College Mental Health. Curr Psychiatry Rep. 2018 Aug 09; 20(9):72. PMID: 30094519.
      View in: PubMed
    2. Skehan B, Davis M. Aligning Mental Health Treatments with the Developmental Stage and Needs of Late Adolescents and Young Adults. Child Adolesc Psychiatr Clin N Am. 2017 Apr; 26(2):177-190. PMID: 28314449.
      View in: PubMed
    3. Kailasan Vanaja S, Rathinam VA, Atianand MK, Kalantari P, Skehan B, Fitzgerald KA, Leong JM. Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome. Proc Natl Acad Sci U S A. 2014 May 27; 111(21):7765-70. PMID: 24828532.
      View in: PubMed
    4. Aitio O, Hellman M, Skehan B, Kesti T, Leong JM, Saksela K, Permi P. Enterohaemorrhagic Escherichia coli exploits a tryptophan switch to hijack host f-actin assembly. Structure. 2012 Oct 10; 20(10):1692-703. PMID: 22921828; PMCID: PMC3472031.
    5. Vingadassalom D, Campellone KG, Brady MJ, Skehan B, Battle SE, Robbins D, Kapoor A, Hecht G, Snapper SB, Leong JM. Enterohemorrhagic E. coli requires N-WASP for efficient type III translocation but not for EspFU-mediated actin pedestal formation. PLoS Pathog. 2010; 6(8). PMID: 20808845.
      View in: PubMed
    6. Vingadassalom D, Kazlauskas A, Skehan B, Cheng HC, Magoun L, Robbins D, Rosen MK, Saksela K, Leong JM. Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formation. Proc Natl Acad Sci U S A. 2009 Apr 21; 106(16):6754-9. PMID: 19366662.
      View in: PubMed
    7. Padrick SB, Cheng HC, Ismail AM, Panchal SC, Doolittle LK, Kim S, Skehan BM, Umetani J, Brautigam CA, Leong JM, Rosen MK. Hierarchical regulation of WASP/WAVE proteins. Mol Cell. 2008 Nov 7; 32(3):426-38. PMID: 18995840.
      View in: PubMed
    8. Cheng HC, Skehan BM, Campellone KG, Leong JM, Rosen MK. Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspF(U). Nature. 2008 Aug 21; 454(7207):1009-13. PMID: 18650809.
      View in: PubMed
    9. Campellone KG, Brady MJ, Alamares JG, Rowe DC, Skehan BM, Tipper DJ, Leong JM. Enterohaemorrhagic Escherichia coli Tir requires a C-terminal 12-residue peptide to initiate EspF-mediated actin assembly and harbours N-terminal sequences that influence pedestal length. Cell Microbiol. 2006 Sep; 8(9):1488-503. PMID: 16922867.
      View in: PubMed
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