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Last Name

Nagendra Yadava MS, PhD

TitleAssistant Professor
InstitutionUMMS - Baystate Regional Campus
DepartmentMedicine at UMMS-Baystate
AddressBaystate Health Regional Campus
3601 Main Street
Springfield MA 01107
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    Collapse Biography 
    Collapse education and training
    Banaras Hindu University, Varanasi, UP, IndiaBSBotany/Chemistry/Zoology
    University of Baroda, Baroda, , IndiaMSBiotechnology
    Jawaharlal Nehru University, New Delhi, , IndiaPHDLife Sciences

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ozay EI, Sherman HL, Mello V, Trombley G, Lerman A, Tew GN, Yadava N, Minter LM. Rotenone Treatment Reveals a Role for Electron Transport Complex I in the Subcellular Localization of Key Transcriptional Regulators During T Helper Cell Differentiation. Front Immunol. 2018; 9:1284. PMID: 29930555.
      View in: PubMed
    2. Wong KE, Mora MC, Sultana N, Moriarty KP, Arenas RB, Yadava N, Schneider SS, Tirabassi MV. Evaluation of Rhodiola crenulata on growth and metabolism of NB-1691, an MYCN-amplified neuroblastoma cell line. Tumour Biol. 2018 Jun; 40(6):1010428318779515. PMID: 29871587.
      View in: PubMed
    3. Kim C, Potluri P, Khalil A, Gaut D, McManus M, Compton S, Wallace DC, Yadava N. An X-chromosome linked mouse model (Ndufa1S55A) for systemic partial Complex I deficiency for studying predisposition to neurodegeneration and other diseases. Neurochem Int. 2017 Oct; 109:78-93. PMID: 28506826.
      View in: PubMed
    4. Schneider SS, Henchey EM, Sultana N, Morin SM, Jerry DJ, Makari-Judson G, Crisi GM, Arenas RB, Johnson M, Mason HS, Yadava N. Individual-specific Variation in the Respiratory Activities of HMECs and Their Bioenergetic Response to IGF1 and TNFa. J Cell Physiol. 2017 Mar 28. PMID: 28369883.
      View in: PubMed
    5. Bordt EA, Clerc P, Roelofs BA, Saladino AJ, Tretter L, Adam-Vizi V, Cherok E, Khalil A, Yadava N, Ge SX, Francis TC, Kennedy NW, Picton LK, Kumar T, Uppuluri S, Miller AM, Itoh K, Karbowski M, Sesaki H, Hill RB, Polster BM. The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species. Dev Cell. 2017 03 27; 40(6):583-594.e6. PMID: 28350990.
      View in: PubMed
    6. Sen S, Domingues CC, Rouphael C, Chou C, Kim C, Yadava N. Genetic modification of human mesenchymal stem cells helps to reduce adiposity and improve glucose tolerance in an obese diabetic mouse model. Stem Cell Res Ther. 2015 Dec 09; 6:242. PMID: 26652025.
      View in: PubMed
    7. Yadav N, Kumar S, Kumar R, Srivastava P, Sun L, Rapali P, Marlowe T, Schneider A, Inigo JR, O'Malley J, Londonkar R, Gogada R, Chaudhary AK, Yadava N, Chandra D. Mechanism of neem limonoids-induced cell death in cancer: Role of oxidative phosphorylation. Free Radic Biol Med. 2016 Jan; 90:261-71. PMID: 26627937; PMCID: PMC4734361 [Available on 01/01/17].
    8. Yadav N, Kumar S, Marlowe T, Chaudhary AK, Kumar R, Wang J, O'Malley J, Boland PM, Jayanthi S, Kumar TK, Yadava N, Chandra D. Oxidative phosphorylation-dependent regulation of cancer cell apoptosis in response to anticancer agents. Cell Death Dis. 2015 Nov 05; 6:e1969. PMID: 26539916; PMCID: PMC4670921.
    9. Kim C, Patel P, Gouvin LM, Brown ML, Khalil A, Henchey EM, Heuck AP, Yadava N. Comparative Analysis of the Mitochondrial Physiology of Pancreatic ß Cells. Bioenergetics. 2014 Mar 01; 3(1):110. PMID: 25309834.
      View in: PubMed
    10. Quinlan CL, Goncalves RL, Hey-Mogensen M, Yadava N, Bunik VI, Brand MD. The 2-oxoacid dehydrogenase complexes in mitochondria can produce superoxide/hydrogen peroxide at much higher rates than complex I. J Biol Chem. 2014 Mar 21; 289(12):8312-25. PMID: 24515115; PMCID: PMC3961658.
    11. Divakaruni AS, Wiley SE, Rogers GW, Andreyev AY, Petrosyan S, Loviscach M, Wall EA, Yadava N, Heuck AP, Ferrick DA, Henry RR, McDonald WG, Colca JR, Simon MI, Ciaraldi TP, Murphy AN. Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):5422-7. PMID: 23513224; PMCID: PMC3619368.
    12. Yadava N, Schneider SS, Jerry DJ, Kim C. Impaired mitochondrial metabolism and mammary carcinogenesis. J Mammary Gland Biol Neoplasia. 2013 Mar; 18(1):75-87. PMID: 23269521.
      View in: PubMed
    13. Compton S, Kim C, Griner NB, Potluri P, Scheffler IE, Sen S, Jerry DJ, Schneider S, Yadava N. Mitochondrial dysfunction impairs tumor suppressor p53 expression/function. J Biol Chem. 2011 Jun 10; 286(23):20297-312. PMID: 21502317.
      View in: PubMed
    14. Gerencser AA, Neilson A, Choi SW, Edman U, Yadava N, Oh RJ, Ferrick DA, Nicholls DG, Brand MD. Quantitative microplate-based respirometry with correction for oxygen diffusion. Anal Chem. 2009 Aug 15; 81(16):6868-78. PMID: 19555051.
      View in: PubMed
    15. Chinta SJ, Rane A, Yadava N, Andersen JK, Nicholls DG, Polster BM. Reactive oxygen species regulation by AIF- and complex I-depleted brain mitochondria. Free Radic Biol Med. 2009 Apr 01; 46(7):939-47. PMID: 19280713; PMCID: PMC2775507.
    16. Amo T, Yadava N, Oh R, Nicholls DG, Brand MD. Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T. Gene. 2008 Mar 31; 411(1-2):69-76. PMID: 18280061; PMCID: PMC2270349.
    17. Nicholls DG, Johnson-Cadwell L, Vesce S, Jekabsons M, Yadava N. Bioenergetics of mitochondria in cultured neurons and their role in glutamate excitotoxicity. J Neurosci Res. 2007 Nov 15; 85(15):3206-12. PMID: 17455297.
      View in: PubMed
    18. Yadava N, Potluri P, Scheffler IE. Investigations of the potential effects of phosphorylation of the MWFE and ESSS subunits on complex I activity and assembly. Int J Biochem Cell Biol. 2008; 40(3):447-60. PMID: 17931954.
      View in: PubMed
    19. Yadava N, Nicholls DG. Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone. J Neurosci. 2007 Jul 04; 27(27):7310-7. PMID: 17611283.
      View in: PubMed
    20. Mamelak AJ, Kowalski J, Murphy K, Yadava N, Zahurak M, Kouba DJ, Howell BG, Tzu J, Cummins DL, Liégeois NJ, Berg K, Sauder DN. Downregulation of NDUFA1 and other oxidative phosphorylation-related genes is a consistent feature of basal cell carcinoma. Exp Dermatol. 2005 May; 14(5):336-48. PMID: 15854127.
      View in: PubMed
    21. Scheffler IE, Yadava N, Potluri P. Molecular genetics of complex I-deficient Chinese hamster cell lines. Biochim Biophys Acta. 2004 Dec 06; 1659(2-3):160-71. PMID: 15576048.
      View in: PubMed
    22. Potluri P, Yadava N, Scheffler IE. The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase). Eur J Biochem. 2004 Aug; 271(15):3265-73. PMID: 15265046.
      View in: PubMed
    23. Ricci JE, Muñoz-Pinedo C, Fitzgerald P, Bailly-Maitre B, Perkins GA, Yadava N, Scheffler IE, Ellisman MH, Green DR. Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain. Cell. 2004 Jun 11; 117(6):773-86. PMID: 15186778.
      View in: PubMed
    24. Yadava N, Scheffler IE. Import and orientation of the MWFE protein in mitochondrial NADH-ubiquinone oxidoreductase. Mitochondrion. 2004 Jun; 4(1):1-12. PMID: 16120368.
      View in: PubMed
    25. Yadava N, Houchens T, Potluri P, Scheffler IE. Development and characterization of a conditional mitochondrial complex I assembly system. J Biol Chem. 2004 Mar 26; 279(13):12406-13. PMID: 14722084.
      View in: PubMed
    26. Yadava N, Potluri P, Smith EN, Bisevac A, Scheffler IE. Species-specific and mutant MWFE proteins. Their effect on the assembly of a functional mammalian mitochondrial complex I. J Biol Chem. 2002 Jun 14; 277(24):21221-30. PMID: 11937507.
      View in: PubMed
    27. Scheffler IE, Yadava N. Molecular genetics of the mammalian NADH-ubiquinone oxidoreductase. J Bioenerg Biomembr. 2001 Jun; 33(3):243-50. PMID: 11695834.
      View in: PubMed
    28. Mohanty S, Lee S, Yadava N, Dealy MJ, Johnson RS, Firtel RA. Regulated protein degradation controls PKA function and cell-type differentiation in Dictyostelium. Genes Dev. 2001 Jun 01; 15(11):1435-48. PMID: 11390363; PMCID: PMC312710.
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