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Howard Smithline MD

TitleAssociate Professor
InstitutionUMass Chan – Baystate Regional Campus
DepartmentEmergency Medicine at UMass Chan - Baystate
AddressBaystate Health Regional Campus
759 Chestnut Street
Springfield MA 01199
Phone413-794-3343
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    Collapse Biography 
    Collapse education and training
    Northwestern University Feinberg School of Medicine, Chicago, IL, United StatesBSMedicine
    University of Michigan, Ann Arbor, Ann Arbor, MI, United StatesMSStats Analysis/Clinical Design
    Northwestern University Feinberg School of Medicine, Chicago, IL, United StatesMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Whitfield NN, Hogan CA, Chenoweth J, Hansen J, Hsu EB, Humphries R, Mann E, May L, Michelson EA, Rothman R, Self WH, Smithline HA, Karita HCS, Steingrub JS, Swedien D, Weissman A, Wright DW, Liesenfeld O, Shapiro NI. A standardized protocol using clinical adjudication to define true infection status in patients presenting to the emergency department with suspected infections and/or sepsis. Diagn Microbiol Infect Dis. 2024 Sep; 110(1):116382. PMID: 38850687.
      Citations:    
    2. Mohr NM, Plumb ID, Santos Le?n E, Harland KK, Krishnadasan A, Nandi U, Hoth KF, Smithline HA, Talan DA. Factors associated with the decision to receive bivalent COVID-19 booster vaccination among health care personnel. Hum Vaccin Immunother. 2023 12 15; 19(3):2284471. PMID: 37994545.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    3. Plumb ID, Briggs Hagen M, Wiegand R, Dumyati G, Myers C, Harland KK, Krishnadasan A, James Gist J, Abedi G, Fleming-Dutra KE, Chea N, Lee JE, Kellogg M, Edmundson A, Britton A, Wilson LE, Lovett SA, Ocampo V, Markus TM, Smithline HA, Hou PC, Lee LC, Mower W, Rwamwejo F, Steele MT, Lim SC, Schrading WA, Chinnock B, Beiser DG, Faine B, Haran JP, Nandi U, Chipman AK, LoVecchio F, Eucker S, Femling J, Fuller M, Rothman RE, Curlin ME, Talan DA, Mohr NM. Effectiveness of a bivalent mRNA vaccine dose against symptomatic SARS-CoV-2 infection among U.S. Healthcare personnel, September 2022-May 2023. Vaccine. 2024 Apr 11; 42(10):2543-2552. PMID: 37973512.
      Citations:    Fields:    
    4. Plumb ID, Mohr NM, Hagen M, Wiegand R, Dumyati G, Harland KK, Krishnadasan A, Gist JJ, Abedi G, Fleming-Dutra KE, Chea N, Lee J, Barter D, Brackney M, Fridkin SK, Wilson LE, Lovett SA, Ocampo V, Phipps EC, Marcus TM, Smithline HA, Hou PC, Lee LC, Moran GJ, Krebs E, Steele MT, Lim SC, Schrading WA, Chinnock B, Beiser DG, Faine B, Haran JP, Nandi U, Chipman AK, LoVecchio F, Talan DA, Pilishvili T. Effectiveness of a Messenger RNA Vaccine Booster Dose Against Coronavirus Disease 2019 Among US Healthcare Personnel, October 2021-July 2022. Open Forum Infect Dis. 2023 Oct; 10(10):ofad457. PMID: 37799130.
      Citations:    
    5. Pilishvili T, Gierke R, Fleming-Dutra KE, Farrar JL, Mohr NM, Talan DA, Krishnadasan A, Harland KK, Smithline HA, Hou PC, Lee LC, Lim SC, Moran GJ, Krebs E, Steele MT, Beiser DG, Faine B, Haran JP, Nandi U, Schrading WA, Chinnock B, Henning DJ, Lovecchio F, Lee J, Barter D, Brackney M, Fridkin SK, Marceaux-Galli K, Lim S, Phipps EC, Dumyati G, Pierce R, Markus TM, Anderson DJ, Debes AK, Lin MY, Mayer J, Kwon JH, Safdar N, Fischer M, Singleton R, Chea N, Magill SS, Verani JR, Schrag SJ. Effectiveness of mRNA Covid-19 Vaccine among U.S. Health Care Personnel. N Engl J Med. 2021 12 16; 385(25):e90. PMID: 34551224.
      Citations: 117     Fields:    Translation:Humans
    6. Pilishvili T, Fleming-Dutra KE, Farrar JL, Gierke R, Mohr NM, Talan DA, Krishnadasan A, Harland KK, Smithline HA, Hou PC, Lee LC, Lim SC, Moran GJ, Krebs E, Steele M, Beiser DG, Faine B, Haran JP, Nandi U, Schrading WA, Chinnock B, Henning DJ, LoVecchio F, Nadle J, Barter D, Brackney M, Britton A, Marceaux-Galli K, Lim S, Phipps EC, Dumyati G, Pierce R, Markus TM, Anderson DJ, Debes AK, Lin M, Mayer J, Babcock HM, Safdar N, Fischer M, Singleton R, Chea N, Magill SS, Verani J, Schrag S. Interim Estimates of Vaccine Effectiveness of Pfizer-BioNTech and Moderna COVID-19 Vaccines Among Health Care Personnel - 33 U.S. Sites, January-March 2021. MMWR Morb Mortal Wkly Rep. 2021 May 21; 70(20):753-758. PMID: 34014909.
      Citations: 93     Fields:    Translation:Humans
    7. Self WH, Semler MW, Leither LM, Casey JD, Angus DC, Brower RG, Chang SY, Collins SP, Eppensteiner JC, Filbin MR, Files DC, Gibbs KW, Ginde AA, Gong MN, Harrell FE, Hayden DL, Hough CL, Johnson NJ, Khan A, Lindsell CJ, Matthay MA, Moss M, Park PK, Rice TW, Robinson BRH, Schoenfeld DA, Shapiro NI, Steingrub JS, Ulysse CA, Weissman A, Yealy DM, Thompson BT, Brown SM, Steingrub J, Smithline H, Tiru B, Tidswell M, Kozikowski L, Thornton-Thompson S, De Souza L, Hou P, Baron R, Massaro A, Aisiku I, Fredenburgh L, Seethala R, Johnsky L, Riker R, Seder D, May T, Baumann M, Eldridge A, Lord C, Shapiro N, Talmor D, O?Mara T, Kirk C, Harrison K, Kurt L, Schermerhorn M, Banner-Goodspeed V, Boyle K, Dubosh N, Filbin M, Hibbert K, Parry B, Lavin-Parsons K, Pulido N, Lilley B, Lodenstein C, Margolin J, Brait K, Jones A, Galbraith J, Peacock R, Nandi U, Wachs T, Matthay M, Liu K, Kangelaris K, Wang R, Calfee C, Yee K, Hendey G, Chang S, Lim G, Qadir N, Tam A, Beutler R, Levitt J, Wilson J, Rogers A, Vojnik R, Roque J, Albertson T, Chenoweth J, Adams J, Pearson S, Juarez M, Almasri E, Fayed M, Hughes A, Hillard S, Huebinger R, Wang H, Vidales E, Patel B, Ginde A, Moss M, Baduashvili A, McKeehan J, Finck L, Higgins C, Howell M, Douglas I, Haukoos J, Hiller T, Lyle C, Cupelo A, Caruso E, Camacho C, Gravitz S, Finigan J, Griesmer C, Park P, Hyzy R, Nelson K, McDonough K, Olbrich N, Williams M, Kapoor R, Nash J, Willig M, Ford H, Gardner-Gray J, Ramesh M, Moses M, Ng Gong M, Aboodi M, Asghar A, Amosu O, Torres M, Kaur S, Chen JT, Hope A, Lopez B, Rosales K, Young You J, Mosier J, Hypes C, Natt B, Borg B, Salvagio Campbell E, Hite RD, Hudock K, Cresie A, Alhasan F, Gomez-Arroyo J, Duggal A, Mehkri O, Hastings A, Sahoo D, Abi Fadel F, Gole S, Shaner V, Wimer A, Meli Y, King A, Terndrup T, Exline M, Pannu S, Robart E, Karow S, Hough C, Robinson B, Johnson N, Henning D, Campo M, Gundel S, Seghal S, Katsandres S, Dean S, Khan A, Krol O, Jouzestani M, Huynh P, Weissman A, Yealy D, Scholl D, Adams P, McVerry B, Huang D, Angus D, Schooler J, Moore S, Files C, Miller C, Gibbs K, LaRose M, Flores L, Koehler L, Morse C, Sanders J, Langford C, Nanney K, MdalaGausi M, Yeboah P, Morris P, Sturgill J, Seif S, Cassity E, Dhar S, de Wit M, Mason J, Goodwin A, Hall G, Grady A, Chamberlain A, Brown S, Bledsoe J, Leither L, Peltan I, Starr N, Fergus M, Aston V, Montgomery Q, Smith R, Merrill M, Brown K, Armbruster B, Harris E, Middleton E, Paine R, Johnson S, Barrios M, Eppensteiner J, Limkakeng A, McGowan L, Porter T, Bouffler A, Leahy JC, deBoisblanc B, Lammi M, Happel K, Lauto P, Self W, Casey J, Semler M, Collins S, Harrell F, Lindsell C, Rice T, Stubblefield W, Gray C, Johnson J, Roth M, Hays M, Torr D, Zakaria A, Schoenfeld D, Thompson T, Hayden D, Ringwood N, Oldmixon C, Ulysse C, Morse R, Muzikansky A, Fitzgerald L, Whitaker S, Lagakos A, Brower R, Reineck L, Aggarwal N, Bienstock K, Freemer M, Maclawiw M, Weinmann G, Morrison L, Gillespie M, Kryscio R, Brodie D, Zareba W, Rompalo A, Boeckh M, Parsons P, Christie J, Hall J, Horton N, Zoloth L, Dickert N, Diercks D. Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial. JAMA. 2020 12 01; 324(21):2165-2176. PMID: 33165621.
      Citations: 230     Fields:    Translation:Humans
    8. Tenforde MW, Kim SS, Lindsell CJ, Billig Rose E, Shapiro NI, Files DC, Gibbs KW, Erickson HL, Steingrub JS, Smithline HA, Gong MN, Aboodi MS, Exline MC, Henning DJ, Wilson JG, Khan A, Qadir N, Brown SM, Peltan ID, Rice TW, Hager DN, Ginde AA, Stubblefield WB, Patel MM, Self WH, Feldstein LR. Symptom Duration and Risk Factors for Delayed Return to Usual Health Among Outpatients with COVID-19 in a Multistate Health Care Systems Network - United States, March-June 2020. MMWR Morb Mortal Wkly Rep. 2020 Jul 31; 69(30):993-998. PMID: 32730238.
      Citations: 529     Fields:    Translation:HumansPHPublic Health
    9. Tenforde MW, Billig Rose E, Lindsell CJ, Shapiro NI, Files DC, Gibbs KW, Prekker ME, Steingrub JS, Smithline HA, Gong MN, Aboodi MS, Exline MC, Henning DJ, Wilson JG, Khan A, Qadir N, Stubblefield WB, Patel MM, Self WH, Feldstein LR. Characteristics of Adult Outpatients and Inpatients with COVID-19 - 11 Academic Medical Centers, United States, March-May 2020. MMWR Morb Mortal Wkly Rep. 2020 Jul 03; 69(26):841-846. PMID: 32614810.
      Citations: 95     Fields:    Translation:HumansPHPublic Health
    10. Smithline HA, Donnino M, Blank FSJ, Barus R, Coute RA, Knee AB, Visintainer P. Supplemental thiamine for the treatment of acute heart failure syndrome: a randomized controlled trial. BMC Complement Altern Med. 2019 May 06; 19(1):96. PMID: 31060559.
      Citations: 4     Fields:    Translation:Humans
    11. Selker HP, Kwong M, Ruthazer R, Gorman S, Green G, Patchen E, Udelson JE, Smithline HA, Baumann MR, Harris PA, Shah RU, Nelson SJ, Cohen T, Jones EB, Barnewolt BA, Williams AE. An example of medical device-based projection of clinical trial enrollment: Use of electrocardiographic data to identify candidates for a trial in acute coronary syndromes. J Clin Transl Sci. 2018 Dec; 2(6):377-383. PMID: 31404280.
      Citations:    
    12. Trotter Z, Spirko B, Smithline H, Garb J. Prevalence of Inconsistencies in the Recorded Outcomes of Clinical Evaluations. Pediatr Emerg Care. 2017 Apr; 33(4):245-249. PMID: 26125531.
      Citations:    Fields:    Translation:Humans
    13. Donnino MW, Andersen LW, Berg KM, Chase M, Sherwin R, Smithline H, Carney E, Ngo L, Patel PV, Liu X, Cutlip D, Zimetbaum P, Cocchi MN. Corticosteroid therapy in refractory shock following cardiac arrest: a randomized, double-blind, placebo-controlled, trial. Crit Care. 2016 Apr 03; 20:82. PMID: 27038920.
      Citations: 18     Fields:    Translation:Humans
    14. Donnino MW, Andersen LW, Chase M, Berg KM, Tidswell M, Giberson T, Wolfe R, Moskowitz A, Smithline H, Ngo L, Cocchi MN. Randomized, Double-Blind, Placebo-Controlled Trial of Thiamine as a Metabolic Resuscitator in Septic Shock: A Pilot Study. Crit Care Med. 2016 Feb; 44(2):360-7. PMID: 26771781.
      Citations: 90     Fields:    Translation:Humans
    15. Rathlev N, Almomen R, Deutsch A, Smithline H, Li H, Visintainer P. Randomized Controlled Trial of Electronic Care Plan Alerts and Resource Utilization by High Frequency Emergency Department Users with Opioid Use Disorder. West J Emerg Med. 2016 Jan; 17(1):28-34. PMID: 26823927.
      Citations: 7     Fields:    Translation:Humans
    16. Russell FM, Moore CL, Courtney DM, Kabrhel C, Smithline HA, Nordenholz KE, Richman PB, O'Neil BJ, Plewa MC, Beam DM, Mastouri R, Kline JA. Independent evaluation of a simple clinical prediction rule to identify right ventricular dysfunction in patients with shortness of breath. Am J Emerg Med. 2015 Apr; 33(4):542-7. PMID: 25769797.
      Citations: 4     Fields:    Translation:Humans
    17. Wilcox SR, Seigel TA, Strout TD, Schneider JI, Mitchell PM, Marcolini EG, Cocchi MN, Smithline HA, Lutfy-Clayton L, Mullen M, Ilgen JS, Richards JB. Emergency medicine residents' knowledge of mechanical ventilation. J Emerg Med. 2015 Apr; 48(4):481-91. PMID: 25497896.
      Citations: 15     Fields:    Translation:Humans
    18. Hasegawa K, Tsugawa Y, Lopez BL, Smithline HA, Sullivan AF, Camargo CA. Body mass index and risk of hospitalization among adults presenting with asthma exacerbation to the emergency department. Ann Am Thorac Soc. 2014 Nov; 11(9):1439-44. PMID: 25314160.
      Citations: 9     Fields:    Translation:Humans
    19. Nowak RM, Parker JM, Silverman RA, Rowe BH, Smithline H, Khan F, Fiening JP, Kim K, Molfino NA. A randomized trial of benralizumab, an antiinterleukin 5 receptor a monoclonal antibody, after acute asthma. Am J Emerg Med. 2015 Jan; 33(1):14-20. PMID: 25445859.
      Citations: 56     Fields:    Translation:HumansCTClinical Trials
    20. Tutay GJ, Capraro G, Spirko B, Garb J, Smithline H. Electrolyte profile of pediatric patients with hypertrophic pyloric stenosis. Pediatr Emerg Care. 2013 Apr; 29(4):465-8. PMID: 23528507.
      Citations: 7     Fields:    Translation:Humans
    21. Venkatesh AK, Kline JA, Courtney DM, Camargo CA, Plewa MC, Nordenholz KE, Moore CL, Richman PB, Smithline HA, Beam DM, Kabrhel C. Evaluation of pulmonary embolism in the emergency department and consistency with a national quality measure: quantifying the opportunity for improvement. Arch Intern Med. 2012 Jul 09; 172(13):1028-32. PMID: 22664742.
      Citations: 27     Fields:    Translation:HumansPHPublic Health
    22. Kline JA, Hogg MM, Courtney DM, Miller CD, Jones AE, Smithline HA. D-dimer threshold increase with pretest probability unlikely for pulmonary embolism to decrease unnecessary computerized tomographic pulmonary angiography. J Thromb Haemost. 2012 Apr; 10(4):572-81. PMID: 22284935.
      Citations: 13     Fields:    Translation:Humans
    23. Smithline HA, Donnino M, Greenblatt DJ. Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects. BMC Clin Pharmacol. 2012 Feb 04; 12:4. PMID: 22305197.
      Citations: 36     Fields:    Translation:Humans
    24. Greenman RL, Wang X, Smithline HA. Simultaneous acquisition of phosphocreatine and inorganic phosphate images for Pi:PCr ratio mapping using a RARE sequence with chemically selective interleaving. Magn Reson Imaging. 2011 Oct; 29(8):1138-44. PMID: 21641744.
      Citations: 10     Fields:    Translation:Humans
    25. Greenman RL, Smithline HA. The feasibility of measuring phosphocreatine recovery kinetics in muscle using a single-shot (31)P RARE MRI sequence. Acad Radiol. 2011 Jul; 18(7):917-23. PMID: 21536463.
      Citations: 12     Fields:    Translation:Humans
    26. Wu JS, Buettner C, Smithline H, Ngo LH, Greenman RL. Evaluation of skeletal muscle during calf exercise by 31-phosphorus magnetic resonance spectroscopy in patients on statin medications. Muscle Nerve. 2011 Jan; 43(1):76-81. PMID: 21171098.
      Citations: 21     Fields:    Translation:Humans
    27. Smithline HA, Caglar S, Blank FS. Assessing validity by comparing transition and static measures of dyspnea in patients with acute decompensated heart failure. Congest Heart Fail. 2010 Sep-Oct; 16(5):202-7. PMID: 20887616.
      Citations: 4     Fields:    Translation:Humans
    28. Kabrhel C, Mark Courtney D, Camargo CA, Plewa MC, Nordenholz KE, Moore CL, Richman PB, Smithline HA, Beam DM, Kline JA. Factors associated with positive D-dimer results in patients evaluated for pulmonary embolism. Acad Emerg Med. 2010 Jun; 17(6):589-97. PMID: 20624138.
      Citations: 58     Fields:    Translation:Humans
    29. Kline JA, Hogg MM, Courtney DM, Miller CD, Jones AE, Smithline HA, Klekowski N, Lanier R. D-dimer and exhaled CO2/O2 to detect segmental pulmonary embolism in moderate-risk patients. Am J Respir Crit Care Med. 2010 Sep 01; 182(5):669-75. PMID: 20448094.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    30. Smithline HA, Caglar S, Blank FS. Physician vs patient assessment of dyspnea during acute decompensated heart failure. Congest Heart Fail. 2010 Mar-Apr; 16(2):60-4. PMID: 20412470.
      Citations: 5     Fields:    Translation:Humans
    31. Kline JA, Courtney DM, Than MP, Hogg K, Miller CD, Johnson CL, Smithline HA. Accuracy of very low pretest probability estimates for pulmonary embolism using the method of attribute matching compared with the Wells score. Acad Emerg Med. 2010 Feb; 17(2):133-41. PMID: 20370742.
      Citations: 6     Fields:    Translation:Humans
    32. Camargo CA, Gurner DM, Smithline HA, Chapela R, Fabbri LM, Green SA, Malice MP, Legrand C, Dass SB, Knorr BA, Reiss TF. A randomized placebo-controlled study of intravenous montelukast for the treatment of acute asthma. J Allergy Clin Immunol. 2010 Feb; 125(2):374-80. PMID: 20159247.
      Citations: 24     Fields:    Translation:Humans
    33. Donnino MW, Cocchi MN, Smithline H, Carney E, Chou PP, Salciccioli J, Salciccoli J. Coronary artery bypass graft surgery depletes plasma thiamine levels. Nutrition. 2010 Jan; 26(1):133-6. PMID: 20005469.
      Citations: 18     Fields:    Translation:Humans
    34. Courtney DM, Kline JA, Kabrhel C, Moore CL, Smithline HA, Nordenholz KE, Richman PB, Plewa MC. Clinical features from the history and physical examination that predict the presence or absence of pulmonary embolism in symptomatic emergency department patients: results of a prospective, multicenter study. Ann Emerg Med. 2010 Apr; 55(4):307-315.e1. PMID: 20045580.
      Citations: 16     Fields:    Translation:Humans
    35. Courtney DM, Miller C, Smithline H, Klekowski N, Hogg M, Kline JA. Prospective multicenter assessment of interobserver agreement for radiologist interpretation of multidetector computerized tomographic angiography for pulmonary embolism. J Thromb Haemost. 2010 Mar; 8(3):533-9. PMID: 20015156.
      Citations: 12     Fields:    Translation:Humans
    36. Henneman PL, Garb JL, Capraro GA, Li H, Smithline HA, Wait RB. Geography and travel distance impact emergency department visits. J Emerg Med. 2011 Mar; 40(3):333-9. PMID: 20005663.
      Citations: 13     Fields:    Translation:Humans
    37. Marchick MR, Courtney DM, Kabrhel C, Nordenholz KE, Plewa MC, Richman PB, Smithline HA, Kline JA. 12-lead ECG findings of pulmonary hypertension occur more frequently in emergency department patients with pulmonary embolism than in patients without pulmonary embolism. Ann Emerg Med. 2010 Apr; 55(4):331-5. PMID: 19766353.
      Citations: 3     Fields:    Translation:Humans
    38. Smithline HA, Rudnitzky N, Macomber S, Blank FS. Pulse oximetry using a disposable finger sensor placed on the forehead in hypoxic patients. J Emerg Med. 2010 Jul; 39(1):121-5. PMID: 19406607.
      Citations: 2     Fields:    Translation:Humans
    39. Kabrhel C, Mark Courtney D, Camargo CA, Moore CL, Richman PB, Plewa MC, Nordenholtz KE, Smithline HA, Beam DM, Brown MD, Kline JA. Potential impact of adjusting the threshold of the quantitative D-dimer based on pretest probability of acute pulmonary embolism. Acad Emerg Med. 2009 Apr; 16(4):325-32. PMID: 19298619.
      Citations: 11     Fields:    Translation:Humans
    40. Henneman PL, Nathanson BH, Li H, Smithline HA, Blank FS, Santoro JP, Maynard AM, Provost DA, Henneman EA. Emergency department patients who stay more than 6 hours contribute to crowding. J Emerg Med. 2010 Jul; 39(1):105-12. PMID: 19157757.
      Citations: 24     Fields:    Translation:Humans
    41. Capraro GA, Coughlin BF, Mader TJ, Smithline HA. Testicular cooling associated with testicular torsion and its detection by infrared thermography: an experimental study in sheep. J Urol. 2008 Dec; 180(6):2688-93. PMID: 18951560.
      Citations: 3     Fields:    Translation:Animals
    42. Caglar S, Henneman PL, Blank FS, Smithline HA, Henneman EA. Emergency department medication lists are not accurate. J Emerg Med. 2011 Jun; 40(6):613-6. PMID: 18829201.
      Citations: 22     Fields:    Translation:Humans
    43. Henneman PL, Lemanski M, Smithline HA, Tomaszewski A, Mayforth JA. Emergency department admissions are more profitable than non-emergency department admissions. Ann Emerg Med. 2009 Feb; 53(2):249-255. PMID: 18786746.
      Citations: 8     Fields:    Translation:Humans
    44. Blank FS, Miller M, Nichols J, Smithline H, Crabb G, Pekow P. Blood glucose measurement in patients with suspected diabetic ketoacidosis: a comparison of Abbott MediSense PCx point-of-care meter values to reference laboratory values. J Emerg Nurs. 2009 Apr; 35(2):93-6. PMID: 19285169.
      Citations: 3     Fields:    Translation:Humans
    45. Kline JA, Courtney DM, Kabrhel C, Moore CL, Smithline HA, Plewa MC, Richman PB, O'Neil BJ, Nordenholz K. Prospective multicenter evaluation of the pulmonary embolism rule-out criteria. J Thromb Haemost. 2008 May; 6(5):772-80. PMID: 18318689.
      Citations: 89     Fields:    Translation:Humans
    46. Baevsky RH, Haber MD, Blank FS, Smithline H. Supine vs semirecumbent and upright 12-lead electrocardiogram: does change in body position alter the electrocardiographic interpretation for ischemia? Am J Emerg Med. 2007 Sep; 25(7):753-6. PMID: 17870476.
      Citations: 2     Fields:    Translation:Humans
    47. Smithline HA. Acute decompensated heart failure. CMAJ. 2007 Jul 17; 177(2):175; author reply 175-6. PMID: 17638957.
      Citations:    Fields:    Translation:Humans
    48. Smithline HA. Thiamine for the treatment of acute decompensated heart failure. Am J Emerg Med. 2007 Jan; 25(1):124-6. PMID: 17157711.
      Citations: 7     Fields:    Translation:Humans
    49. Capraro GA, Mader TJ, Coughlin BF, Lovewell C, St Louis MR, Tirabassi M, Wadie G, Smithline HA. Feasibility of using near-infrared spectroscopy to diagnose testicular torsion: an experimental study in sheep. Ann Emerg Med. 2007 Apr; 49(4):520-5. PMID: 16997426.
      Citations: 7     Fields:    Translation:Animals
    50. Lee SY, Coughlin B, Wolfe JM, Polino J, Blank FS, Smithline HA. Prospective comparison of helical CT of the abdomen and pelvis without and with oral contrast in assessing acute abdominal pain in adult Emergency Department patients. Emerg Radiol. 2006 May; 12(4):150-7. PMID: 16738930.
      Citations: 22     Fields:    Translation:Humans
    51. Wolfe JM, Smithline H, Lee S, Coughlin B, Polino J, Blank F. The impact of body mass index on concordance in the interpretation of matched noncontrast and contrast abdominal pelvic computed tomographic scans in ED patients with nontraumatic abdominal pain. Am J Emerg Med. 2006 Mar; 24(2):144-8. PMID: 16490641.
      Citations: 1     Fields:    Translation:Humans
    52. Lemanski M, Smithline H, Blank FS, Henneman PL. Accuracy of laceration length estimation. Am J Emerg Med. 2005 Nov; 23(7):920-1. PMID: 16291461.
      Citations: 2     Fields:    Translation:Humans
    53. Smithline HA, Rowe BH, Radeos MS, Cydulka RK, Camargo CA. Research opportunities in the management of acute exacerbations of chronic obstructive pulmonary disease. Acad Emerg Med. 2005 Aug; 12(8):742-50. PMID: 16079428.
      Citations: 2     Fields:    Translation:Humans
    54. Blank FS, Li H, Henneman PL, Smithline HA, Santoro JS, Provost D, Maynard AM. A descriptive study of heavy emergency department users at an academic emergency department reveals heavy ED users have better access to care than average users. J Emerg Nurs. 2005 Apr; 31(2):139-44. PMID: 15834378.
      Citations: 41     Fields:    Translation:Humans
    55. Griffin JA, Playe SJ, Osborne B, Smithline HA. A report of dangerously high carbon monoxide levels within the passenger compartment of a snow-obstructed vehicle. BMC Emerg Med. 2004 Oct 10; 4(1):4. PMID: 15473913.
      Citations:    Fields:    
    56. Baevsky RH, Kapur RK, Smithline HA. Beckman Access versus the Bayer ACS:180 and the Abbott AxSYM cardiac Troponin-I real-time immunoassays: an observational prospective study. BMC Emerg Med. 2004 Jul 13; 4(1):2. PMID: 15248900.
      Citations:    Fields:    
    57. Baevsky RH, Lu MY, Smithline HA. The effectiveness of wireless telephone communication technology on ambient noise level reduction within the ED. Am J Emerg Med. 2004 Jul; 22(4):317-8. PMID: 15258879.
      Citations:    Fields:    Translation:HumansPHPublic Health
    58. Wolfe JM, Smithline HA, Phipen S, Montano G, Garb JL, Fiallo V. Does morphine change the physical examination in patients with acute appendicitis? Am J Emerg Med. 2004 Jul; 22(4):280-5. PMID: 15258869.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    59. Huynh LN, Coughlin BF, Wolfe J, Blank F, Lee SY, Smithline HA. Patient encounter time intervals in the evaluation of emergency department patients requiring abdominopelvic CT: oral contrast versus no contrast. Emerg Radiol. 2004 Jul; 10(6):310-3. PMID: 15278712.
      Citations: 11     Fields:    Translation:Humans
    60. Baevsky RH, Nyquist SN, Roy MN, Smithline HA. Antipyretic effectiveness of intravenous ketorolac tromethamine. J Emerg Med. 2004 May; 26(4):407-10. PMID: 15093845.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    61. Arnold JL, Halpern P, Tsai MC, Smithline H. Mass casualty terrorist bombings: a comparison of outcomes by bombing type. Ann Emerg Med. 2004 Feb; 43(2):263-73. PMID: 14747818.
      Citations: 19     Fields:    Translation:Humans
    62. Smithline H. Use of natriuretic peptides in guiding treatment decisions for acute pulmonary embolism. Circulation. 2003 Sep 30; 108(13):e93; author reply e93. PMID: 14517155.
      Citations:    Fields:    Translation:Humans
    63. Fordyce J, Blank FS, Pekow P, Smithline HA, Ritter G, Gehlbach S, Benjamin E, Henneman PL. Errors in a busy emergency department. Ann Emerg Med. 2003 Sep; 42(3):324-33. PMID: 12944883.
      Citations: 47     Fields:    Translation:Humans
    64. Mader TJ, Blank FS, Smithline HA, Wolfe JM. How reliable are pain scores? A pilot study of 20 healthy volunteers. J Emerg Nurs. 2003 Aug; 29(4):322-5. PMID: 12874553.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    65. Arnold JL, Tsai MC, Halpern P, Smithline H, Stok E, Ersoy G. Mass-casualty, terrorist bombings: epidemiological outcomes, resource utilization, and time course of emergency needs (Part I). Prehosp Disaster Med. 2003 Jul-Sep; 18(3):220-34. PMID: 15141862.
      Citations: 18     Fields:    Translation:HumansPHPublic Health
    66. Smithline HA, Thompson M, Moran C, Mader TJ. Can CK-MB and cTn-I be detected in the peripheral circulation within the first 10 min of acute coronary ischemia? Med Hypotheses. 2003 Apr; 60(4):598-602. PMID: 12615531.
      Citations:    Fields:    Translation:Humans
    67. Mader TJ, Smithline HA, Durkin L, Scriver G. A randomized controlled trial of intravenous aminophylline for atropine-resistant out-of-hospital asystolic cardiac arrest. Acad Emerg Med. 2003 Mar; 10(3):192-7. PMID: 12615581.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    68. Smithline HA, Mader TJ, Ali FM, Cocchi MN. Determining pretest probability of DVT: clinical intuition vs. validated scoring systems. Am J Emerg Med. 2003 Mar; 21(2):161-2. PMID: 12671824.
      Citations:    Fields:    Translation:Humans
    69. Smithline HA, Ward KR, Chiulli DA, Blake HC, Rivers EP. Whole body oxygen consumption and critical oxygen delivery in response to prolonged and severe carbon monoxide poisoning. Resuscitation. 2003 Jan; 56(1):97-104. PMID: 12505745.
      Citations: 9     Fields:    Translation:Animals
    70. Camargo CA, Smithline HA, Malice MP, Green SA, Reiss TF. A randomized controlled trial of intravenous montelukast in acute asthma. Am J Respir Crit Care Med. 2003 Feb 15; 167(4):528-33. PMID: 12456380.
      Citations: 28     Fields:    Translation:HumansCTClinical Trials
    71. Blank FS, Smithline HA. Evaluation of an educational video for cardiac patients. Clin Nurs Res. 2002 Nov; 11(4):403-16. PMID: 12413113.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    72. Mader TJ, Smithline HA, Nyquist S, Letourneau P. Social services referral of adolescent trauma patients admitted following alcohol-related injury. J Subst Abuse Treat. 2001 Oct; 21(3):167-72. PMID: 11728791.
      Citations:    Fields:    Translation:HumansPHPublic Health
    73. Smith DC, Mader TJ, Smithline HA. Low dose intravenous ketamine as an analgesic: a pilot study using an experimental model of acute pain. Am J Emerg Med. 2001 Oct; 19(6):531-2. PMID: 11593484.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    74. Santoro JP, Blank FS, Smithline H. Follow-up of discrepancies in X-ray and electrocardiogram interpretations, and positive laboratory results. J Emerg Med. 2001 Apr; 20(3):315-9. PMID: 11267826.
      Citations:    Fields:    Translation:Humans
    75. Arnopolin SL, Smithline HA. Patient care by physician assistants and by physicians in an emergency department. JAAPA. 2000 Dec; 13(12):39-40, 49-50, 53-4 passim. PMID: 11523490.
      Citations: 4     Fields:    Translation:Humans
    76. Griffin J, Smithline H, Cook J. Runaway pacemaker: a case report and review. J Emerg Med. 2000 Aug; 19(2):177-81. PMID: 10903469.
      Citations:    Fields:    Translation:Humans
    77. Wolfe JM, Lein DY, Lenkoski K, Smithline HA. Analgesic administration to patients with an acute abdomen: a survey of emergency medicine physicians. Am J Emerg Med. 2000 May; 18(3):250-3. PMID: 10830676.
      Citations: 14     Fields:    Translation:Humans
    78. Smith DC, Bergen JM, Smithline H, Kirschner R. A trial of etomidate for rapid sequence intubation in the emergency department. J Emerg Med. 2000 Jan; 18(1):13-6. PMID: 10645829.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    79. Smithline HA, Mader TJ, Crenshaw BJ. Do patients with acute medical conditions have the capacity to give informed consent for emergency medicine research? Acad Emerg Med. 1999 Aug; 6(8):776-80. PMID: 10463547.
      Citations: 17     Fields:    Translation:Humans
    80. Mader TJ, Smithline HA, Gibson P. Aminophylline in undifferentiated out-of-hospital asystolic cardiac arrest. Resuscitation. 1999 Jun; 41(1):39-45. PMID: 10459591.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    81. Rivers EP, Blake HC, Dereczyk B, Ressler JA, Talos EL, Patel R, Smithline HA, Rady MY, Wortsman J. Adrenal dysfunction in hemodynamically unstable patients in the emergency department. Acad Emerg Med. 1999 Jun; 6(6):626-30. PMID: 10386680.
      Citations: 5     Fields:    Translation:Humans
    82. Baevsky RH, Fisher AL, Smithline HA, Salzberg MR. The influence of physician attire on patient satisfaction. Acad Emerg Med. 1998 Jan; 5(1):82-4. PMID: 9444349.
      Citations: 6     Fields:    Translation:Humans
    83. Smithline HA, Gerstle ML. Waiver of informed consent: a survey of emergency medicine patients. Am J Emerg Med. 1998 Jan; 16(1):90-1. PMID: 9451323.
      Citations: 15     Fields:    Translation:Humans
    84. Witting MD, Smithline HA. Orthostatic change in shock index: comparison with traditional tilt test definitions. Acad Emerg Med. 1996 Oct; 3(10):926-31. PMID: 8891038.
      Citations:    Fields:    Translation:Humans
    85. Rady MY, Smithline HA, Blake H, Nowak R, Rivers E. A comparison of the shock index and conventional vital signs to identify acute, critical illness in the emergency department. Ann Emerg Med. 1994 Oct; 24(4):685-90. PMID: 8092595.
      Citations: 74     Fields:    Translation:Humans
    86. Adams CP, Martin GB, Rivers EP, Ward KR, Smithline HA, Rady MY. Hemodynamics of interposed abdominal compression during human cardiopulmonary resuscitation. Acad Emerg Med. 1994 Sep-Oct; 1(5):498-502. PMID: 7614309.
      Citations:    Fields:    Translation:Humans
    87. Smithline HA, Rivers EP, Rady MY, Blake HC, Nowak RM. Biphasic extrathoracic pressure CPR. A human pilot study. Chest. 1994 Mar; 105(3):842-6. PMID: 8131549.
      Citations:    Fields:    Translation:Humans
    88. Schultz CH, Rivers EP, Feldkamp CS, Goad EG, Smithline HA, Martin GB, Fath JJ, Wortsman J, Nowak RM. A characterization of hypothalamic-pituitary-adrenal axis function during and after human cardiac arrest. Crit Care Med. 1993 Sep; 21(9):1339-47. PMID: 8396524.
      Citations: 24     Fields:    Translation:Humans
    89. Smithline H, Rivers E, Appleton T, Nowak R. Corticosteroid supplementation during cardiac arrest in rats. Resuscitation. 1993 Jun; 25(3):257-64. PMID: 8351423.
      Citations: 5     Fields:    Translation:Animals
    90. Rivers EP, Rady MY, Martin GB, Fenn NM, Smithline HA, Alexander ME, Nowak RM. Venous hyperoxia after cardiac arrest. Characterization of a defect in systemic oxygen utilization. Chest. 1992 Dec; 102(6):1787-93. PMID: 1446489.
      Citations: 17     Fields:    Translation:Humans
    91. Rady MY, Rivers EP, Martin GB, Smithline H, Appelton T, Nowak RM. Continuous central venous oximetry and shock index in the emergency department: use in the evaluation of clinical shock. Am J Emerg Med. 1992 Nov; 10(6):538-41. PMID: 1388378.
      Citations: 32     Fields:    Translation:Humans
    92. Rivers EP, Martin GB, Smithline H, Rady MY, Schultz CH, Goetting MG, Appleton TJ, Nowak RM. The clinical implications of continuous central venous oxygen saturation during human CPR. Ann Emerg Med. 1992 Sep; 21(9):1094-101. PMID: 1514720.
      Citations: 9     Fields:    Translation:Humans
    93. Rivers EP, Paradis NA, Martin GB, Goetting ME, Rosenberg JA, Smithline HA, Appleton TJ, Nowak RM. Cerebral lactate uptake during cardiopulmonary resuscitation in humans. J Cereb Blood Flow Metab. 1991 May; 11(3):479-84. PMID: 2016356.
      Citations: 5     Fields:    Translation:Humans
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