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Last Name

Jeff D Colbert PhD

InstitutionUniversity of Massachusetts Medical School
AddressUniversity of Massachusetts Medical School
368 Plantation Street
Worcester MA 01605
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    Other Positions
    InstitutionUMMS - School of Medicine

    Collapse Biography 
    Collapse education and training
    Kansas State University, Manhattan, KS, United StatesBSMicrobiology
    University of Colorado, Denver, Denver, CO, United StatesPHDImmunology
    University of Dundee, Dundee, UKPostdoctoral FellowImmunology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Colbert JD, Rock KL. How a tailor achieves the perfect fit. J Biol Chem. 2020 May 22; 295(21):7211-7212. PMID: 32444419.
      View in: PubMed
    2. Colbert JD, Cruz FM, Rock KL. Cross-presentation of exogenous antigens on MHC I molecules. Curr Opin Immunol. 2020 Jan 09; 64:1-8. PMID: 31927332.
      View in: PubMed
    3. Cruz FM, Colbert JD, Rock KL. The GTPase Rab39a promotes phagosome maturation into MHC-I antigen-presenting compartments. EMBO J. 2019 Dec 10; e102020. PMID: 31821587.
      View in: PubMed
    4. Orlowski GM, Sharma S, Colbert JD, Bogyo M, Robertson SA, Kataoka H, Chan FK, Rock KL. Frontline Science: Multiple cathepsins promote inflammasome-independent, particle-induced cell death during NLRP3-dependent IL-1ß activation. J Leukoc Biol. 2017 Jan 13. PMID: 28087651.
      View in: PubMed
    5. Cruz FM, Colbert JD, Merino E, Kriegsman BA, Rock KL. The Biology and Underlying Mechanisms of Cross-Presentation of Exogenous Antigens on MHC-I Molecules. Annu Rev Immunol. 2017 Jan 11. PMID: 28125356.
      View in: PubMed
    6. Matthews SP, McMillan SJ, Colbert JD, Lawrence RA, Watts C. Cystatin F Ensures Eosinophil Survival by Regulating Granule Biogenesis. Immunity. 2016 Apr 19; 44(4):795-806. PMID: 27067058; PMCID: PMC4846977.
    7. Orlowski GM, Colbert JD, Sharma S, Bogyo M, Robertson SA, Rock KL. Correction: Multiple Cathepsins Promote Pro-IL-1ß Synthesis and NLRP3-Mediated IL-1ß Activation. J Immunol. 2016 Jan 1; 196(1):503. PMID: 26685316.
      View in: PubMed
    8. Orlowski GM, Colbert JD, Sharma S, Bogyo M, Robertson SA, Rock KL. Multiple Cathepsins Promote Pro-IL-1ß Synthesis and NLRP3-Mediated IL-1ß Activation. J Immunol. 2015 Aug 15; 195(4):1685-97. PMID: 26195813.
      View in: PubMed
    9. Rock KL, Farfán-Arribas DJ, Colbert JD, Goldberg AL. Re-examining class-I presentation and the DRiP hypothesis. Trends Immunol. 2014 Apr; 35(4):144-52. PMID: 24566257.
      View in: PubMed
    10. Colbert JD, Farfán-Arribas DJ, Rock KL. Substrate-induced protein stabilization reveals a predominant contribution from mature proteins to peptides presented on MHC class I. J Immunol. 2013 Dec 1; 191(11):5410-9. PMID: 24174619.
      View in: PubMed
    11. Meriin AB, Mense M, Colbert JD, Liang F, Bihler H, Zaarur N, Rock KL, Sherman MY. A novel approach to recovery of function of mutant proteins by slowing down translation. J Biol Chem. 2012 Oct 05; 287(41):34264-72. PMID: 22902621.
      View in: PubMed
    12. Magister S, Obermajer N, Mirkovic B, Svajger U, Renko M, Softic A, Romih R, Colbert JD, Watts C, Kos J. Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells. Eur J Cell Biol. 2012 May; 91(5):391-401. PMID: 22365146.
      View in: PubMed
    13. Colbert JD, Matthews SP, Kos J, Watts C. Internalization of exogenous cystatin F supresses cysteine proteases and induces the accumulation of single-chain cathepsin L by multiple mechanisms. J Biol Chem. 2011 Dec 09; 286(49):42082-90. PMID: 21956111; PMCID: PMC3234946.
    14. van Kasteren SI, Berlin I, Colbert JD, Keane D, Ovaa H, Watts C. A multifunctional protease inhibitor to regulate endolysosomal function. ACS Chem Biol. 2011 Nov 18; 6(11):1198-204. PMID: 21910425; PMCID: PMC3220280.
    15. Colbert JD, Matthews SP, Miller G, Watts C. Diverse regulatory roles for lysosomal proteases in the immune response. Eur J Immunol. 2009 Nov; 39(11):2955-65. PMID: 19637232.
      View in: PubMed
    16. Colbert JD, Plechanovová A, Watts C. Glycosylation directs targeting and activation of cystatin f from intracellular and extracellular sources. Traffic. 2009 Apr; 10(4):425-37. PMID: 19192250; PMCID: PMC2691902.
    17. Hamilton G, Colbert JD, Schuettelkopf AW, Watts C. Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis. EMBO J. 2008 Feb 06; 27(3):499-508. PMID: 18256700; PMCID: PMC2241651.
    18. Schaack J, Bennett ML, Colbert JD, Torres AV, Clayton GH, Ornelles D, Moorhead J. E1A and E1B proteins inhibit inflammation induced by adenovirus. Proc Natl Acad Sci U S A. 2004 Mar 02; 101(9):3124-9. PMID: 14976240; PMCID: PMC365754.
    19. Soond SM, Terry JL, Colbert JD, Riches DW. TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB. Mol Cell Biol. 2003 Nov; 23(22):8334-44. PMID: 14585990; PMCID: PMC262424.
    20. Maier H, Colbert J, Fitzsimmons D, Clark DR, Hagman J. Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site. Mol Cell Biol. 2003 Mar; 23(6):1946-60. PMID: 12612069.
      View in: PubMed
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