Azithromycin inhibits muscarinic 2 receptor-activated and voltage-activated Ca2+ permeant ion channels and Ca2+ sensitization, relaxing airway smooth muscle contraction.
Wang Q, Yu MF, Zhang WJ, Liu BB, Zhao QY, Luo X, Xu H, She YS, Zang DA, Qiu JY, Shen J, Peng YB, Zhao P, Xue L, Chen W, Ma LQ, Nie X, Shen C, Chen S, Chen S, Liu Q, Dai J, Qin G, Zheng YM, Wang YX, ZhuGe R, Chen J, Liu QH. Azithromycin inhibits muscarinic 2 receptor-activated and voltage-activated Ca2+ permeant ion channels and Ca2+ sensitization, relaxing airway smooth muscle contraction. Clin Exp Pharmacol Physiol. 2019 Apr; 46(4):329-336.