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Shyam Ajay Patel MD, PhD

TitleAssociate Professor
InstitutionUMass Chan Medical School
DepartmentMedicine
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
Phone774-442-6553
Email
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMedicine
    DivisionHematology/Oncology

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentCancer Biology


    Collapse Biography 
    Collapse education and training
    Drexel University, Philadelphia, PA, United StatesBSBiological Sciences
    Stanford University, Stanford, CAResidency2016Internal Medicine
    Stanford University, Stanford, CAFellowship2019Hematology
    Rutgers - New Jersey Medical School, Newark, NJMD2013Medicine
    Stanford University, Stanford, CAFellowship2019Oncology
    Rutgers New Jersey Medical School, Newark, NJ, United StatesMD
    Rutgers University Newark, Newark, NJ, United StatesPHDStem Cell Biology/Cancer Biolo
    Rutgers - Graduate School of Biomedical Sciences, Newark, NJPhD2011Stem Cell Biology, Cancer Biology
    Collapse awards and honors
    202340 Under 40, Drexel University
    2022CCTS Pilot Project Program Award, UMass Chan Medical School
    2021Best Educator Award - Hematology/Oncology Fellowship, UMass Chan Medical School
    2019Board Certification - ABIM Medical Oncology, Stanford University
    2019Board Certification - ABIM Hematology, Stanford University
    2018American Society of Hematology (ASH) Trainee Council - Appointed Member, Stanford University
    2018NIH T32 – Ruth L. Kirschstein Nat’l Research Service Award, Stanford University
    2017Nat’l Comprehensive Cancer Network (NCCN) Oncology Fellows Educational Grant, Stanford University
    2016Board Certification - ABIM Internal Medicine, Stanford University
    2013Merck Manual Award for Overall Academic Achievement, Rutgers - New Jersey Medical School
    2012American Society of Hematology (ASH) Trainee Research Award (HONORS Award), Rutgers - New Jersey Medical School
    2011Alpha Omega Alpha (AOA) Medical Honors Society - Junior Induction, Rutgers - New Jersey Medical School
    2010Alpha Omega Alpha (AOA) Medical Student Research Award, Rutgers - New Jersey Medical School
    2010The Dean Morris Schaffer Endowed Scholarship Fund, Rutgers - Graduate School of Biomedical Sciences
    2006The Dr. Wilhelm Frisell Award for Best Performance in Rutgers-NJMS Biochemistry, Rutgers - New Jersey Medical School
    2006Summa Cum Laude, Drexel University
    2006Best Poster Presentation, Eighth Annual Research Day, Drexel University
    2005The Damon M. Fellman, M.D. Scholarship, Hackensack University Medical Center
    2004The Alvin Seligson, M.D. Scholarship, Hackensack University Medical Center

    Collapse Overview 
    Collapse overview

    Dr. Patel attended Rutgers – New Jersey Medical School and Rutgers - Graduate School of Biomedical Sciences from 2006-13, where he completed the physician-scientist training program (PSTP). He trained in the disciplines of stem cell biology and cancer biology. His thesis research focused on breast cancer dormancy in the bone marrow. He then completed Internal Medicine residency at Stanford University (2013-16) and Hematology/Oncology fellowship at Stanford University (2016-19), during which time he studied the leukemic stem cell niche in acute myeloid leukemia (AML). He is board-certified in Internal Medicine (2016), Hematology (2019), and Medical Oncology (2019).

    He is Co-Director of the Blood, Immunity, and Infection course at UMass Chan Medical School.

    His current research involves understanding the disease biology and clonal dynamics of TP53-mutant MDS and AML, as well as the genomics of clonal hematopoiesis (Patel SA et al., Br J Haematol 2024). He leads the efforts in the UMass CHIP Clinic (www.umassmed.edu/chip-clinic).


    Collapse media links

    Collapse Research 
    Collapse research activities and funding
    NIH T32     Feb 1, 2018 - Jan 31, 2019
    NIH
    Investigating Leukemia Stem Cell Niche Interactions in Acute Myeloid Leukemia
    Role Description: Laboratory of Ravindra Majeti, MD, PhD, Stanford University
    UL1TR001453     Jun 1, 2022 - May 31, 2023
    NIH / National Center for Advancing Translational Sciences (NCATS): UMass CCTS 2022 Pilot Project Program
    Clinical Translation of an Innovative Leukemia Stem Cell Assay for Detection, Prognostication, and Precision Management of Blood Cancer
    Role Description: Laboratory of Dr. Jonathan Gerber, UMass Chan Medical School

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Jamy O, El Kettani M, Shah K, Shallis RM, Diebold K, Coltoff A, Goldberg AD, Patel A, Bewersdorf JP, Foucar C, Abaza Y, Palmisiano N, DuVall AS, Kota V, Patel SA, Zeidan AM, Atallah E, Litzow MR, Badar T. Outcomes of older patients with TP53-mutated myeloid neoplasms. Blood Cancer J. 2025 Oct 07; 15(1):160. PMID: 41057316.
      Citations:    
    2. Patel SA, Bennett JM. The evolving nosology of myeloid neoplasms: the semi-centennial of the 1976 French-American-British classification. Leukemia. 2025 Aug 26. PMID: 40858808.
      Citations:    
    3. Zhang TY, Ge AY, Epstein MM, Patel SA. Treatment patterns and survival outcomes for very elderly patients with acute myeloid leukemia: A National Cancer Database study. Leuk Res. 2025 Oct; 157:108086. PMID: 40848471.
      Citations:    
    4. Sudireddy K, Amin M, Odeh R, Svrcek P, Khedr S, Hutchinson L, Patel SA, Cerny J, Pearson L. Effective treatment of peritoneal myeloid sarcoma with decitabine and venetoclax: A case report. Leuk Res Rep. 2025; 24:100534. PMID: 40837405.
      Citations:    
    5. Patel SA, Khedr S, Gordon CD, Nuvvula S, Littman N, Woda B, Hutchinson L, Li S, Xie Y, Selove W, Cerny J, Gerber JM. Early identification of TP53 mutations and TP53 allelic state in myelodysplastic neoplasms and acute myeloid leukemia via point-of-care p53 immunohistochemistry. Cancer. 2025 Jul 01; 131(13):e35950. PMID: 40542737.
      Citations:    
    6. Mehta RS, Schmidt G, Williams K, Patel SA, Schetelig J, Savani B, Askar M, Petersdorf E, Ringden O, Kanakry CG, Kanakry JA, Stefanski H, Arrieta-Bola?os E, Betts B, Benjamin C, Gadalla S, Wang T, Saultz J, Spellman S, Jurdi NE, Bolon YT, Lee SJ. Choosing Between HLA-Mismatched Unrelated and Haploidentical Donors: Donor Age Considerations. Transplant Cell Ther. 2025 Sep; 31(9):680-692. PMID: 40419020.
      Citations:    
    7. Ramanathan R, Xie Y, Badar T, Zeidan AM, Patel SA. Contemporary management paradigms and emerging therapeutics for myelodysplastic syndromes/neoplasms. Br J Haematol. 2025 Jun; 206(6):1571-1581. PMID: 40302714.
      Citations:    
    8. Khouri MR, Wang B, Pearson LK, Gillis-Smith AJ, Suzuki S, Hutchinson LM, Bindal P, Ramanathan M, Gerber JM, Cerny J, Patel SA. Characteristics and clinical outcomes of patients with myeloid malignancies and cohesin mutations. Cancer. 2025 Apr 15; 131(8):e35846. PMID: 40219906.
      Citations:    
    9. Gerber WK, Xie Y, Patel SA. Expanding the Therapeutic Reach of Chimeric Antigen Receptor T-Cells and Bispecific T-Cell Engagers Across Solid Tumors. JCO Precis Oncol. 2025 Mar; 9:e2400753. PMID: 40138603.
      Citations:    
    10. Patel SA, Spiegel JY, Dahiya S. Second Primary Cancer After Chimeric Antigen Receptor-T-Cell Therapy: A Review. JAMA Oncol. 2025 Feb 01; 11(2):174-181. PMID: 39666320.
      Citations:    
    11. Patel SA, Weeks LD. Drafting a blueprint for designing successful clinical trials in clonal haematopoiesis. Br J Haematol. 2025 Feb; 206(2):800-802. PMID: 39654077.
      Citations:    
    12. Patel SA, Isidori A, Cerchione C, Aureli A. Editorial: Immunobiology and immunotherapeutics in myelodysplastic syndrome and acute myeloid leukemia. Front Immunol. 2024; 15:1500864. PMID: 39478868.
      Citations:    
    13. Patel SA. Managing the unmanageable: evidence-driven approaches to real-world patient prototypes of TP53-mutant myelodysplastic neoplasms and acute myeloid leukemia. Leukemia. 2024 Dec; 38(12):2544-2551. PMID: 39349613.
      Citations:    
    14. Xie Y, Kazakova V, Weeks LD, Gerber JM, Tai J, Zhang TY, Lowsky R, Wu X, Yang C, Patel SA. Effects of donor-engrafted clonal hematopoiesis in allogeneic and autologous stem cell transplantation: a systematic review and meta-analysis. Bone Marrow Transplant. 2024 Nov; 59(11):1585-1593. PMID: 39183321.
      Citations:    
    15. Cammann E, Madhav S, Hutchinson L, Cerny J, Ramanathan M, Bledsoe JR, Makarenko V, Patel SA, Meng X, Tomaszewicz K, Nath R, Chen B, Woda B, Selove W. Frameshift Mutations in Leukemia-Associated Genes Correlate With Superior Outcomes in Patients Undergoing Allogeneic Stem Cell Transplant for De Novo Acute Myeloid Leukemia. J Hematol. 2024 Jun; 13(3):86-93. PMID: 38993741.
      Citations:    
    16. Yaniv B, Tanenbaum B, Kazakova V, Patel SA. Translational insights into the genetics and immunobiology of relapsed/refractory follicular lymphoma. Leuk Res. 2024 Jul; 142:107519. PMID: 38761562.
      Citations:    
    17. Patel SA, Gerber WK, Zheng R, Khanna S, Hutchinson L, Abel GA, Cerny J, DaSilva BA, Zhang TY, Ramanathan M, Khedr S, Selove W, Woda B, Miron PM, Higgins AW, Gerber JM. Natural history of clonal haematopoiesis seen in real-world haematology settings. Br J Haematol. 2024 May; 204(5):1844-1855. PMID: 38522849.
      Citations:    
    18. Ferrer-Diaz AI, Sinha G, Petryna A, Gonzalez-Bermejo R, Kenfack Y, Adetayo O, Patel SA, Hooda-Nehra A, Rameshwar P. Revealing role of epigenetic modifiers and DNA oxidation in cell-autonomous regulation of Cancer stem cells. Cell Commun Signal. 2024 02 12; 22(1):119. PMID: 38347590.
      Citations:    
    19. Patel SA. The heart of VIALE-A: Cardiac complications of hypomethylating agents and venetoclax in acute myeloid leukaemia. Br J Haematol. 2024 Apr; 204(4):1137-1138. PMID: 38339780.
      Citations:    Fields:    
    20. Kennedy A, Patel S, Ramanathan M, Gerber J, Cerny J. Midostaurin for FLT3-mutated AML: a real-world analysis of effectiveness and infection risk at a single center. Ann Hematol. 2024 Mar; 103(3):1031-1033. PMID: 38195923.
      Citations:    Fields:    
    21. Bello E, Liao H, Patel SA. Clinico-Radio-Pathologic Correlation of Leukostasis in Acute Myeloid Leukemia with FLT3 Mutation. Acta Haematol. 2024; 147(3):388-390. PMID: 37788644.
      Citations:    Fields:    
    22. Patel SA, Bello E, Wilks A, Gerber JM, Sadagopan N, Cerny J. Harnessing autologous immune effector mechanisms in acute myeloid leukemia: 2023 update of trials and tribulations. Leuk Res. 2023 11; 134:107388. PMID: 37729719.
      Citations:    Fields:    Translation:Humans
    23. Patel SA, Cerny J, Gerber WK, Ramanathan M, Ediriwickrema A, Tanenbaum B, Hutchinson L, Meng X, Flahive J, Barton B, Gillis-Smith AJ, Suzuki S, Khedr S, Selove W, Higgins AW, Miron PM, Simin K, Woda B, Gerber JM. Prognostic heterogeneity and clonal dynamics within distinct subgroups of myelodysplastic syndrome and acute myeloid leukemia with TP53 disruptions. EJHaem. 2023 Nov; 4(4):1059-1070. PMID: 38024632.
      Citations:    
    24. Arun Kumar S, Gao J, Patel SA. The shifting therapeutic paradigm for relapsed/refractory mantle cell lymphoma. Leuk Res. 2023 11; 134:107385. PMID: 37672954.
      Citations: 1     Fields:    Translation:Humans
    25. Gao J, Dahiya S, Patel SA. Challenges and solutions to superior chimeric antigen receptor-T design and deployment for B-cell lymphomas. Br J Haematol. 2023 10; 203(2):161-168. PMID: 37488074.
      Citations:    Fields:    Translation:Humans
    26. Patel SA. Precision and strategic targeting of novel mutation-specific vulnerabilities in acute myeloid leukemia: the semi-centennial of 7?+?3. Leuk Lymphoma. 2023 09; 64(9):1503-1513. PMID: 37328939.
      Citations:    Fields:    Translation:Humans
    27. Thomas E, Kennedy A, Walsh W, Carpentier M, Adeyinka H, Patel S, Gerber J, Cerny J, Mittal K. Telehealth through the pandemic at a safety net hospital: observations and next steps for cancer care delivery. Front Public Health. 2023; 11:1186350. PMID: 37333537.
      Citations:    Fields:    Translation:HumansPHPublic Health
    28. Tanenbaum B, Miett T, Patel SA. The emerging therapeutic landscape of relapsed/refractory multiple myeloma. Ann Hematol. 2023 Jan; 102(1):1-11. PMID: 36462062.
      Citations: 4     Fields:    
    29. Patel SA, Cerny J. TP53-mutant myelodysplastic syndrome and acute myeloid leukemia: the black hole of hematology. Blood Adv. 2022 03 22; 6(6):1917-1918. PMID: 35090167.
      Citations: 5     Fields:    Translation:Humans
    30. Patel SA. Functional genomic approaches in acute myeloid leukemia: Insights into disease models and the therapeutic potential of reprogramming. Cancer Lett. 2022 05 01; 533:215579. PMID: 35124146.
      Citations:    Fields:    Translation:HumansCells
    31. Nuvvula S, Dahiya S, Patel SA. The Novel Therapeutic Landscape for Relapsed/Refractory Diffuse Large B Cell Lymphoma. Clin Lymphoma Myeloma Leuk. 2022 06; 22(6):362-372. PMID: 34922844.
      Citations: 4     Fields:    Translation:Humans
    32. Reid SE, Patel SA. Myocarditis, kidney injury, and hypereosinophilia: FIP1L1-PDGFRA-positive myeloid/lymphoid neoplasm with eosinophilia. Blood. 2021 09 23; 138(12):1086. PMID: 34554219.
      Citations:    Fields:    Translation:Humans
    33. Patel SA, Lloyd MR, Cerny J, Shi Q, Simin K, Ediriwickrema A, Hutchinson L, Miron PM, Higgins AW, Ramanathan M, Gerber JM. Clinico-genomic profiling and clonal dynamic modeling of TP53-aberrant myelodysplastic syndrome and acute myeloid leukemia. Leuk Lymphoma. 2021 12; 62(14):3348-3360. PMID: 34496723.
      Citations: 5     Fields:    Translation:Humans
    34. Sherman LS, Patel SA, Castillo MD, Unkovic R, Taborga M, Gergues M, Patterson S, Etchegaray JP, Jaloudi M, Hooda-Nehra A, Kra J, Rojas DP, Chang VT, Rameshwar P. NF?B Targeting in Bone Marrow Mesenchymal Stem Cell-Mediated Support of Age-Linked Hematological Malignancies. Stem Cell Rev Rep. 2021 12; 17(6):2178-2192. PMID: 34410592.
      Citations: 3     Fields:    Translation:HumansCells
    35. Patel SA, Dalela D, Fan AC, Lloyd MR, Zhang TY. Niche-directed therapy in acute myeloid leukemia: optimization of stem cell competition for niche occupancy. Leuk Lymphoma. 2022 01; 63(1):10-18. PMID: 34407733.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    36. Patel SA, Bledsoe JR, Higgins AW, Hutchinson L, Gerber JM. Rapid and Deep Remission Induced by Blinatumomab for CD19-Positive Chronic Myeloid Leukemia in Lymphoid Blast Phase. JCO Precis Oncol. 2021 07; 5. PMID: 34409243.
      Citations: 2     Fields:    Translation:Humans
    37. Patel SA, Litzow MR, Cerny J. Targeted and cytotoxic therapies as maintenance treatment for non-transplant eligible patients with acute myeloid leukemia. Blood Rev. 2021 11; 50:100863. PMID: 34210571.
      Citations: 1     Fields:    Translation:Humans
    38. Wang X, Patel SA, Haddadin M, Cerny J. Post-allogeneic hematopoietic stem cell transplantation viral reactivations and viremias: a focused review on human herpesvirus-6, BK virus and adenovirus. Ther Adv Infect Dis. 2021 Jan-Dec; 8:20499361211018027. PMID: 34104434.
      Citations:    
    39. Sandiford OA, Donnelly RJ, El-Far MH, Burgmeyer LM, Sinha G, Pamarthi SH, Sherman LS, Ferrer AI, DeVore DE, Patel SA, Naaldijk Y, Alonso S, Barak P, Bryan M, Ponzio NM, Narayanan R, Etchegaray JP, Kumar R, Rameshwar P. Mesenchymal Stem Cell-Secreted Extracellular Vesicles Instruct Stepwise Dedifferentiation of Breast Cancer Cells into Dormancy at the Bone Marrow Perivascular Region. Cancer Res. 2021 03 15; 81(6):1567-1582. PMID: 33500249.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    40. Dalela D, Bledsoe JR, Patel SA. Clonal IgH gene rearrangements identify Richter's transformation to diffuse large B cell lymphoma. Ann Hematol. 2021 Dec; 100(12):3075-3077. PMID: 33159568.
      Citations:    Fields:    Translation:Humans
    41. Patel SA, Bledsoe JR, Gordon J, Cerny J. Extramedullary Acute Myeloid Leukemia of the Renal Pelvis: Insights into a Visceral Niche. Acta Haematol. 2021; 144(3):297-301. PMID: 32814320.
      Citations:    Fields:    Translation:Humans
    42. Azizi A, Ediriwickrema A, Dutta R, Patel SA, Shomali W, Medeiros B, Iberri D, Gotlib J, Mannis G, Greenberg P, Majeti R, Zhang T. Venetoclax and hypomethylating agent therapy in high risk myelodysplastic syndromes: a retrospective evaluation of a real-world experience. Leuk Lymphoma. 2020 11; 61(11):2700-2707. PMID: 32543932.
      Citations: 10     Fields:    Translation:Humans
    43. Khan S, Choi J, Patel SA, Spain DA. Altered mental status and hypercalcemia with a splenic mass. J Trauma Acute Care Surg. 2020 03; 88(3):e114-e115. PMID: 31688787.
      Citations:    Fields:    Translation:Humans
    44. Patel SA, Gerber JM. A User's Guide to Novel Therapies for Acute Myeloid Leukemia. Clin Lymphoma Myeloma Leuk. 2020 05; 20(5):277-288. PMID: 32113891.
      Citations: 10     Fields:    Translation:Humans
    45. Patel SA. Myelodysplastic Syndrome and Acute Myeloid Leukemia Risk Associated With Solid Tumor Chemotherapy. JAMA Oncol. 2019 03 01; 5(3):303-304. PMID: 30570644.
      Citations: 4     Fields:    Translation:Humans
    46. Patel SA, Longacre TA, Ladabaum U, Lebensohn A, Lin AY, Haraldsdottir S. Tumor Molecular Testing Guides Anti-PD-1 Therapy and Provides Evidence for Pathogenicity of Mismatch Repair Variants. Oncologist. 2018 12; 23(12):1395-1400. PMID: 30072391.
      Citations: 3     Fields:    Translation:HumansCells
    47. Patel SA. Enasidenib-Induced Differentiation Syndrome in IDH2-Mutant Acute Myeloid Leukemia. JAMA Oncol. 2018 08 01; 4(8):1110-1111. PMID: 29346477.
      Citations: 2     Fields:    Translation:Humans
    48. Silverio KA, Patel SA. Harnessing antitumor immunity: Employment of tumor recall antigens to optimize the inflammatory response to cancer. Oncol Lett. 2017 Apr; 13(4):2015-2020. PMID: 28454356.
      Citations:    
    49. Patel SA. Acute Myeloid Leukemia Relapse Presenting as Complete Monocular Vision Loss due to Optic Nerve Involvement. Case Rep Hematol. 2016; 2016:3794284. PMID: 27668104.
      Citations:    
    50. Silverio KA, Patel SA. Progressive Multifocal Leukoencephalopathy with Negative JC Virus PCR following Treatment of Follicular Lymphoma: Implications for Biologics in the Era of Targeted Cancer Therapy. Case Rep Oncol Med. 2015; 2015:534529. PMID: 26788389.
      Citations:    
    51. Patel SA. The inferior vena cava (IVC) syndrome as the initial manifestation of newly diagnosed gastric adenocarcinoma: a case report. J Med Case Rep. 2015 Sep 28; 9:204. PMID: 26411979.
      Citations: 5     Fields:    Translation:Humans
    52. Nahas GR, Murthy RG, Patel SA, Ganta T, Greco SJ, Rameshwar P. The RNA-binding protein Musashi 1 stabilizes the oncotachykinin 1 mRNA in breast cancer cells to promote cell growth. FASEB J. 2016 Jan; 30(1):149-59. PMID: 26373800.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    53. Guiro K, Patel SA, Greco SJ, Rameshwar P, Arinzeh TL. Investigating breast cancer cell behavior using tissue engineering scaffolds. PLoS One. 2015; 10(3):e0118724. PMID: 25837691.
      Citations: 16     Fields:    Translation:HumansCells
    54. Patel SA, Dave MA, Bliss SA, Giec-Ujda AB, Bryan M, Pliner LF, Rameshwar P. Treg/Th17 polarization by distinct subsets of breast cancer cells is dictated by the interaction with mesenchymal stem cells. J Cancer Stem Cell Res. 2014 May 29; 2014(2). PMID: 25705705.
      Citations:    
    55. Desai MB, Gavrilova T, Liu J, Patel SA, Kartan S, Greco SJ, Capitle E, Rameshwar P. Pollen-induced antigen presentation by mesenchymal stem cells and T cells from allergic rhinitis. Clin Transl Immunology. 2013 Oct; 2(10):e7. PMID: 25505949.
      Citations:    
    56. Rasouli J, Patel SA, Skovrlj B, Gologorsky Y, Mascitelli J, Petersen B, Caridi J. Primary extranodal marginal zone lymphoma involving the skull. J Clin Neurosci. 2014 Feb; 21(2):351-3. PMID: 24094361.
      Citations: 1     Fields:    Translation:Humans
    57. Helmy KY, Patel SA, Nahas GR, Rameshwar P. Cancer immunotherapy: accomplishments to date and future promise. Ther Deliv. 2013 Oct; 4(10):1307-20. PMID: 24116914.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    58. Park JM, Munoz JL, Won BW, Bliss SA, Greco SJ, Patel SA, Kandouz M, Rameshwar P. Exogenous CXCL12 activates protein kinase C to phosphorylate connexin 43 for gap junctional intercellular communication among confluent breast cancer cells. Cancer Lett. 2013 Apr 30; 331(1):84-91. PMID: 23262036.
      Citations: 15     Fields:    Translation:HumansCells
    59. Patel SA, Ramkissoon SH, Bryan M, Pliner LF, Dontu G, Patel PS, Amiri S, Pine SR, Rameshwar P. Delineation of breast cancer cell hierarchy identifies the subset responsible for dormancy. Sci Rep. 2012; 2:906. PMID: 23205268.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    60. Navarro P, Ramkissoon SH, Shah S, Park JM, Murthy RG, Patel SA, Greco SJ, Rameshwar P. An indirect role for oncomir-519b in the expression of truncated neurokinin-1 in breast cancer cells. Exp Cell Res. 2012 Dec 10; 318(20):2604-15. PMID: 22981979.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    61. Munoz JL, Greco SJ, Patel SA, Sherman LS, Bhatt S, Bhatt RS, Shrensel JA, Guan YZ, Xie G, Ye JH, Rameshwar P, Siegel A. Feline bone marrow-derived mesenchymal stromal cells (MSCs) show similar phenotype and functions with regards to neuronal differentiation as human MSCs. Differentiation. 2012 Sep; 84(2):214-22. PMID: 22824626.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    62. Reddy BY, Lim PK, Silverio K, Patel SA, Won BW, Rameshwar P. The Microenvironmental Effect in the Progression, Metastasis, and Dormancy of Breast Cancer: A Model System within Bone Marrow. Int J Breast Cancer. 2012; 2012:721659. PMID: 22482060.
      Citations:    
    63. Greco SJ, Patel SA, Rameshwar P. A reporter assay to detect transfer and targeting of miRNAs in stem cell-breast cancer co-cultures. Methods Mol Biol. 2012; 879:195-201. PMID: 22610562.
      Citations: 2     Fields:    Translation:HumansCells
    64. Nahas GR, Patel SA, Bliss SA, Rameshwar P. Can breast cancer stem cells evade the immune system? Curr Med Chem. 2012; 19(35):6036-49. PMID: 22963570.
      Citations: 4     Fields:    Translation:HumansCells
    65. Kapoor S, Patel SA, Kartan S, Axelrod D, Capitle E, Rameshwar P. Tolerance-like mediated suppression by mesenchymal stem cells in patients with dust mite allergy-induced asthma. J Allergy Clin Immunol. 2012 Apr; 129(4):1094-101. PMID: 22196773.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    66. Sherman LS, Munoz J, Patel SA, Dave MA, Paige I, Rameshwar P. Moving from the laboratory bench to patients' bedside: considerations for effective therapy with stem cells. Clin Transl Sci. 2011 Oct; 4(5):380-6. PMID: 22029813.
      Citations: 13     Fields:    Translation:HumansCells
    67. Patel SA, Rameshwar P. Stem Cell Transplantation for Hematological Malignancies: Prospects for Personalized Medicine and Co-therapy with Mesenchymal Stem Cells. Curr Pharmacogenomics Person Med. 2011 Sep 01; 9(3):229-239. PMID: 21892378.
      Citations:    
    68. Gregory LA, Ricart RA, Patel SA, Lim PK, Rameshwar P. microRNAs, Gap Junctional Intercellular Communication and Mesenchymal Stem Cells in Breast Cancer Metastasis. Curr Cancer Ther Rev. 2011 Aug; 7(3):176-183. PMID: 21886602.
      Citations:    
    69. Patel N, Klassert TE, Greco SJ, Patel SA, Munoz JL, Reddy BY, Bryan M, Campbell N, Kokorina N, Sabaawy HE, Rameshwar P. Developmental regulation of TAC1 in peptidergic-induced human mesenchymal stem cells: implication for spinal cord injury in zebrafish. Stem Cells Dev. 2012 Jan 20; 21(2):308-20. PMID: 21671725.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    70. Greco SJ, Patel SA, Bryan M, Pliner LF, Banerjee D, Rameshwar P. AMD3100-mediated production of interleukin-1 from mesenchymal stem cells is key to chemosensitivity of breast cancer cells. Am J Cancer Res. 2011; 1(6):701-15. PMID: 22016821.
      Citations:    
    71. Patel SA, Dave MA, Murthy RG, Helmy KY, Rameshwar P. Metastatic breast cancer cells in the bone marrow microenvironment: novel insights into oncoprotection. Oncol Rev. 2011 Jun 01; 5(2):93-102. PMID: 21776337.
      Citations:    
    72. Lim PK, Bliss SA, Patel SA, Taborga M, Dave MA, Gregory LA, Greco SJ, Bryan M, Patel PS, Rameshwar P. Gap junction-mediated import of microRNA from bone marrow stromal cells can elicit cell cycle quiescence in breast cancer cells. Cancer Res. 2011 Mar 01; 71(5):1550-60. PMID: 21343399.
      Citations: 223     Fields:    Translation:HumansCells
    73. Helmy KY, Patel SA, Silverio K, Pliner L, Rameshwar P. Stem cells and regenerative medicine: accomplishments to date and future promise. Ther Deliv. 2010 Nov; 1(5):693-705. PMID: 21113422.
      Citations: 15     Fields:    Translation:HumansCells
    74. Patel SA, Meyer JR, Greco SJ, Corcoran KE, Bryan M, Rameshwar P. Mesenchymal stem cells protect breast cancer cells through regulatory T cells: role of mesenchymal stem cell-derived TGF-beta. J Immunol. 2010 May 15; 184(10):5885-94. PMID: 20382885.
      Citations: 166     Fields:    Translation:HumansAnimalsCells
    75. Klassert TE, Patel SA, Rameshwar P. Tachykinins and Neurokinin Receptors in Bone Marrow Functions: Neural-Hematopoietic Link. J Receptor Ligand Channel Res. 2010 Apr 01; 2010(3):51-61. PMID: 20593004.
      Citations:    
    76. Patel SA, Ndabahaliye A, Lim PK, Milton R, Rameshwar P. Challenges in the development of future treatments for breast cancer stem cells. Breast Cancer (Dove Med Press). 2010; 2:1-11. PMID: 25114585.
      Citations:    
    77. Patel SA, Heinrich AC, Reddy BY, Rameshwar P. Inflammatory mediators: Parallels between cancer biology and stem cell therapy. J Inflamm Res. 2009 01 01; 2:13-19. PMID: 20428325.
      Citations:    
    78. Heinrich AC, Patel SA, Reddy BY, Milton R, Rameshwar P. Multi- and inter-disciplinary science in personalized delivery of stem cells for tissue repair. Curr Stem Cell Res Ther. 2009 Jan; 4(1):16-22. PMID: 19149626.
      Citations: 4     Fields:    Translation:HumansCells
    79. Patel SA, Heinrich AC, Reddy BY, Srinivas B, Heidaran N, Rameshwar P. Breast cancer biology: the multifaceted roles of mesenchymal stem cells. J Oncol. 2008; 2008:425895. PMID: 19277104.
      Citations:    
    80. Patel SA, Sherman L, Munoz J, Rameshwar P. Immunological properties of mesenchymal stem cells and clinical implications. Arch Immunol Ther Exp (Warsz). 2008 Jan-Feb; 56(1):1-8. PMID: 18250975.
      Citations: 56     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    81. Zhang C, Khandelwal PJ, Chakraborty R, Cuellar TL, Sarangi S, Patel SA, Cosentino CP, O'Connor M, Lee JC, Tanzi RE, Saunders AJ. An AICD-based functional screen to identify APP metabolism regulators. Mol Neurodegener. 2007 Aug 24; 2:15. PMID: 17718916.
      Citations: 26     Fields:    
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