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Giorgio Giatsidis MD, PhD

TitleAssistant Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentSurgery
AddressUniversity of Massachusetts Medical School
55 Lake Ave North
Worcester MA 01605
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentSurgery
    DivisionPlastic Surgery


    Collapse ORNG Applications 
    Collapse Websites

    Collapse Biography 
    Collapse education and training
    San Raffaele University, Milan, ITALYM.D.09/2009
    Padova University, Padova, ITALY Plastic Surgery05/2015
    Padova University, Padova, ITALYPh.D. (Molecular Biology & Regenerative Medicine)02/2018
    Collapse awards and honors
    2014Excellence in Tutoring, Harvard Medical School
    2016Innovation Discovery Award, Partners Healthcare
    2016Pillar Award, Brigham and Women's Hospital
    2017Fellowship Award, American Association of Plastic Surgeons - European Association of Plastic Surgeons

    Collapse Overview 
    Collapse overview

    I am an academic plastic surgeon-scientist dedicated to improving patients’ care through research and innovation in restorative and regenerative surgery.

    The RESICE (Restorative & Regenerative Surgery Innovation Center) group I lead adopts an integrated approach to comprehensively address multiple areas of need and to successfully achieve its goal of bringing innovation to patient care. Our work includes laboratory-based translational research, clinical trials, development of medical devices, studies on the improvement of surgical education, and investigations on global surgery initiatives. Major areas of interest and focus are listed in the sections below (see: Post-doc section) or on our website.

    We value multidisciplinary and interdisciplinary collaborations within and beyond biomedical sciences. Our extensive network of local, regional, national, and international partners is instrumental to our mission and we are always open to engage in new collaborative efforts to continue to advance it.

    In the last decade, we have been fortunate to work with the federal government (Department of Defense), foundations, and industry. We believe each of these stakeholders are pivotal for transforming health care, and we look forward to further expanding our interactions with them.



    Collapse Rotation Projects

    Our team is committed to provide opportunities to UMMS students to both advance their education and produce scholarly work. Committment and goals are individually discussed and tailored based on the student's interests, goals, needs, and availability. Projects are commonly designed to be led by the student under guidance, and to result in a scientific publication authored by the student. For applications please contact: giorgio.giatsidis@umassmed.edu.

    Areas of specific interest include (but are not limited to):

    - Surgical Education

    - Global Surgery



    Collapse Post Docs

    Our team welcomes applications from individuals interested in advancing clinical care, science, and education through multidisciplinary innovation and research in restorative, regenerative, and global surgery.

    Positions are available for national and international undergraduate, graduate (including residents), and post-graduate students with a broad range of diverse expertise and backgrounds.

    Please submit your request along your CV to: giorgio.giatsidis@umassmed.edu

    Main areas of interest

    * Biological Sciences (wound healing & burns, tissue engineering, scaffolds, tissue mechanobiology, angiogenesis, lymphangiogenesis, tissue regeneration [skeletal muscle, adipose tissue, skin], scarring and fibrosis, aging, tissue allotransplantation)

    * Clinical Sciences (trials in plastic surgery [breast reconstruction, post-bariatric surgery, burns, chronic wounds, fat grafting], microsurgery, extremity trauma and replantation, aesthetic surgery/medicine)

    * Global Surgery & Advocacy

    * Surgical Education (design and evaluation of skill courses, simulation-based training, cadaver-based training, use of Augmented Reality and Virtual Reality in surgical education)

    * Biomedical Engineering (design and development of devices or technologies for wound care, tissue preservation, trauma care, surgical robotics, tissue imaging, and tissue diagnostics)

    * Software Engineering (mHealth applications in surgery, tele-surgery)

    * Art sciences (Medical illustrations)




    Collapse Research 
    Collapse research activities and funding
    n/a     (Giatsidis Giorgio)Feb 1, 2018 - Jan 31, 2022
    Gillian Reny Stepping Strong Foundation Innovator Award
    Mitigating damage to injured limbs after tourniquet application
    Role: Principal Investigator

    DM170398     (Giatsidis Giorgio)Apr 15, 2018 - Mar 14, 2022
    DoD - DMRDP Neuromusculoskeletal Injuries Rehabilitation Research Award
    Regeneration and Enhanced Recovery of Injured Skeletal Muscles Using External, Noninvasive, Passive Mechanical Stimulation
    Role: Principal Investigator

    n/a     (Giatsidis Giorgio)Jun 1, 2020 - May 31, 2022
    DoD - CDMRP Orthopaedic Research Program Applied Research Award
    A wearable Limb Monitoring System (LiMS).
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Loretelli C, Ben Nasr M, Giatsidis G, Bassi R, Lancerotto L, D'Addio F, Valderrama-Vasquez A, Scherer SS, Salvatore L, Madaghiele M, Abdelsalam A, Ippolito E, Assi E, Usuelli V, El Essawy B, Sannino A, Pietramaggiori G, Zuccotti GV, Orgill DP, Fiorina P. Embryonic stem cell extracts improve wound healing in diabetic mice. Acta Diabetol. 2020 Mar 02. PMID: 32124076.
      View in: PubMed
    2. Orgill DP, Wei S, Gundogan B, Giatsidis G. Reply: Delayed Postconditioning with External Volume Expansion Improves Survival of Adipose Tissue Grafts in a Murine Model. Plast Reconstr Surg. 2020 Jan; 145(1):204e. PMID: 31834227.
      View in: PubMed
    3. Giatsidis G. Discussion: Angiotensin II Type I Receptor Blockade Is Associated with Decreased Cutaneous Scar Formation in a Rat Model. Plast Reconstr Surg. 2019 11; 144(5):814e-815e. PMID: 31688757.
      View in: PubMed
    4. Giatsidis G, Succar J, Waters TD, Liu W, Rhodius P, Wang C, Nilsen TJ, Chnari E, Orgill DP. Tissue-Engineered Soft-Tissue Reconstruction Using Noninvasive Mechanical Preconditioning and a Shelf-Ready Allograft Adipose Matrix. Plast Reconstr Surg. 2019 10; 144(4):884-895. PMID: 31568297.
      View in: PubMed
    5. Giatsidis G. Discussion: Flap Blood Glucose as a Sensitive and Specific Indicator for Flap Venous Congestion: A Rodent Model Study. Plast Reconstr Surg. 2019 09; 144(3):419e-420e. PMID: 31461019.
      View in: PubMed
    6. Succar J, Giatsidis G, Yu N, Hassan K, Khouri R, Gurish MF, Pejler G, Åbrink M, Orgill DP. Mouse Mast Cell Protease-4 Recruits Leukocytes in the Inflammatory Phase of Surgically Wounded Skin. Adv Wound Care (New Rochelle). 2019 Oct 01; 8(10):469-475. PMID: 31456904.
      View in: PubMed
    7. Matsumine H, Giatsidis G, Osada A, Kamei W, Fujimaki H, Tsukamoto Y, Hashimoto K, Fujii K, Sakurai H. Keratinocyte sheets prepared with temperature-responsive dishes show enhanced survival after in vivo grafting on acellular dermal matrices in a rat model of staged bi-layered skin reconstruction. Regen Ther. 2019 Dec; 11:167-175. PMID: 31388519.
      View in: PubMed
    8. Giatsidis G, Succar J, Waters TD, Liu W, Rhodius P, Wang C, Nilsen TJ, Chnari E, Orgill DP. Tissue Engineered Soft Tissue Reconstruction Using Non-invasive Mechanical Preconditioning and a Shelf-ready Allograft Adipose Matrix. Plast Reconstr Surg. 2019 Jul 03. PMID: 31299681.
      View in: PubMed
    9. Giatsidis G. Discussion: Ischemic Preconditioning and Iloprost Reduces Ischemia-Reperfusion Injury in Jejunal Flaps: An Animal Model. Plast Reconstr Surg. 2019 07; 144(1):134-135. PMID: 31246815.
      View in: PubMed
    10. Icli B, Wu W, Ozdemir D, Li H, Cheng HS, Haemmig S, Liu X, Giatsidis G, Avci SN, Lee N, Guimaraes RB, Manica A, Marchini JF, Rynning SE, Risnes I, Hollan I, Croce K, Yang X, Orgill DP, Feinberg MW. MicroRNA-615-5p Regulates Angiogenesis and Tissue Repair by Targeting AKT/eNOS (Protein Kinase B/Endothelial Nitric Oxide Synthase) Signaling in Endothelial Cells. Arterioscler Thromb Vasc Biol. 2019 07; 39(7):1458-1474. PMID: 31092013.
      View in: PubMed
    11. Giatsidis G. Discussion: Perioperative Treatment with a Prolyl Hydroxylase Inhibitor Reduces Necrosis in a Rat Ischemic Skin Flap Model. Plast Reconstr Surg. 2019 04; 143(4):780e-781e. PMID: 30921128.
      View in: PubMed
    12. Sinha I, Nabi M, Simko LC, Wolfe AW, Wiechman S, Giatsidis G, Bharadia D, McMullen K, Gibran NS, Kowalske K, Meyer WJ, Kazis LE, Ryan CM, Schneider JC. Head and neck burns are associated with long-term patient-reported dissatisfaction with appearance: A Burn Model System National Database study. Burns. 2019 03; 45(2):293-302. PMID: 30732865.
      View in: PubMed
    13. Wei S, Orgill DP, Giatsidis G. Delivery of External Volume Expansion through Microdeformational Interfaces Safely Induces Angiogenesis in a Murine Model of Intact Diabetic Skin with Endothelial Cell Dysfunction. Plast Reconstr Surg. 2019 02; 143(2):453-464. PMID: 30531623.
      View in: PubMed
    14. Icli B, Wu W, Ozdemir D, Li H, Haemmig S, Liu X, Giatsidis G, Cheng HS, Avci SN, Kurt M, Lee N, Guimaraes RB, Manica A, Marchini JF, Rynning SE, Risnes I, Hollan I, Croce K, Orgill DP, Feinberg MW. MicroRNA-135a-3p regulates angiogenesis and tissue repair by targeting p38 signaling in endothelial cells. FASEB J. 2019 Apr; 33(4):5599-5614. PMID: 30668922.
      View in: PubMed
    15. Contessi Negrini N, Bonnetier M, Giatsidis G, Orgill DP, Farè S, Marelli B. Tissue-mimicking gelatin scaffolds by alginate sacrificial templates for adipose tissue engineering. Acta Biomater. 2019 03 15; 87:61-75. PMID: 30654214.
      View in: PubMed
    16. Wei S, Liu W, Gundogan B, Moscoso AV, Orgill DP, Giatsidis G. Delayed Postconditioning with External Volume Expansion Improves Survival of Adipose Tissue Grafts in a Murine Model. Plast Reconstr Surg. 2019 01; 143(1):99e-110e. PMID: 30325898.
      View in: PubMed
    17. Rhodius P, Haddad A, Matsumine H, Sakthivel D, Ackermann M, Sinha I, Orgill DP, Giatsidis G. Noninvasive Flap Preconditioning by Foam-Mediated External Suction Improves the Survival of Fasciocutaneous Axial-Pattern Flaps in a Type 2 Diabetic Murine Model. Plast Reconstr Surg. 2018 12; 142(6):872e-883e. PMID: 30188471.
      View in: PubMed
    18. Giatsidis G, Succar J, Haddad A, Lago G, Schaffer C, Wang X, Schilling B, Chnari E, Matsumine H, Orgill DP. Preclinical Optimization of a Shelf-Ready, Injectable, Human-Derived, Decellularized Allograft Adipose Matrix. Tissue Eng Part A. 2019 02; 25(3-4):271-287. PMID: 30084731.
      View in: PubMed
    19. Wang C, Liu C, Giatsidis G, Cheng H, Chen L, Kang D, Panayi AC, Luan J. The Effect of Respiration on Breast Measurement Using Three-dimensional Breast Imaging. Aesthetic Plast Surg. 2019 02; 43(1):53-58. PMID: 30242460.
      View in: PubMed
    20. Abatangelo S, Saporiti E, Giatsidis G. Closed Incision Negative-Pressure Therapy (ciNPT) Reduces Minor Local Complications in Post-bariatric Abdominoplasty Body Contouring: a Retrospective Case-Control Series. Obes Surg. 2018 07; 28(7):2096-2104. PMID: 29730777.
      View in: PubMed
    21. Giatsidis G, Guyette JP, Ott HC, Orgill DP. Development of a large-volume human-derived adipose acellular allogenic flap by perfusion decellularization. Wound Repair Regen. 2018 03; 26(2):245-250. PMID: 29617055.
      View in: PubMed
    22. Saghazadeh S, Rinoldi C, Schot M, Kashaf SS, Sharifi F, Jalilian E, Nuutila K, Giatsidis G, Mostafalu P, Derakhshandeh H, Yue K, Swieszkowski W, Memic A, Tamayol A, Khademhosseini A. Drug delivery systems and materials for wound healing applications. Adv Drug Deliv Rev. 2018 03 01; 127:138-166. PMID: 29626550.
      View in: PubMed
    23. Sinha I, Giatsidis G, Orgill DP. Discussion: Protective Effect of Hydrogen Gas Inhalation on Muscular Damage Using a Mouse Hindlimb Ischemia-Reperfusion Injury Model. Plast Reconstr Surg. 2017 12; 140(6):1207-1208. PMID: 29176415.
      View in: PubMed
    24. Giatsidis G, Cheng L, Haddad A, Ji K, Succar J, Lancerotto L, Lujan-Hernandez J, Fiorina P, Matsumine H, Orgill DP. Noninvasive induction of angiogenesis in tissues by external suction: sequential optimization for use in reconstructive surgery. Angiogenesis. 2018 02; 21(1):61-78. PMID: 29147813.
      View in: PubMed
    25. Chin MS, Chappell AG, Giatsidis G, Perry DJ, Lujan-Hernandez J, Haddad A, Matsumine H, Orgill DP, Lalikos JF. Hyperspectral Imaging Provides Early Prediction of Random Axial Flap Necrosis in a Preclinical Model. Plast Reconstr Surg. 2017 Jun; 139(6):1285e-1290e. PMID: 28538567.
      View in: PubMed
    26. Nuutila K, Sakthivel D, Kruse C, Tran P, Giatsidis G, Sinha I. Gene expression profiling of skeletal muscle after volumetric muscle loss. Wound Repair Regen. 2017 05; 25(3):408-413. PMID: 28494512.
      View in: PubMed
    27. Giatsidis G, Cheng L, Facchin F, Haddad A, Lujan-Hernandez J, Lancerotto L, Nabzdyk CG, Matsumine H, Orgill DP. Moderate-Intensity Intermittent External Volume Expansion Optimizes the Soft-Tissue Response in a Murine Model. Plast Reconstr Surg. 2017 Apr; 139(4):882-890. PMID: 28350665.
      View in: PubMed
    28. Haddad AG, Giatsidis G, Orgill DP, Halvorson EG. Skin Substitutes and Bioscaffolds: Temporary and Permanent Coverage. Clin Plast Surg. 2017 Jul; 44(3):627-634. PMID: 28576252.
      View in: PubMed
    29. Giatsidis G, Sinha I, Pomahac B. Reflections on a Decade of Face Transplantation. Ann Surg. 2017 04; 265(4):841-846. PMID: 28032849.
      View in: PubMed
    30. Matsumine H, Numakura K, Tsunoda S, Wang H, Matsumine R, Climov M, Giatsidis G, Sukhatme VP, Orgill DP. Adipose-derived aldehyde dehydrogenase-expressing cells promote dermal regenerative potential with collagen-glycosaminoglycan scaffold. Wound Repair Regen. 2017 01; 25(1):109-119. PMID: 28230922.
      View in: PubMed
    31. Cheng L, Ji K, Shih TY, Haddad A, Giatsidis G, Mooney DJ, Orgill DP, Nabzdyk CS. Injectable Shape-Memorizing Three-Dimensional Hyaluronic Acid Cryogels for Skin Sculpting and Soft Tissue Reconstruction. Tissue Eng Part A. 2017 03; 23(5-6):243-251. PMID: 27875939.
      View in: PubMed
    32. Lujan-Hernandez J, Lancerotto L, Nabzdyk C, Hassan KZ, Giatsidis G, Khouri RK, Chin MS, Bassetto F, Lalikos JF, Orgill DP. Reply: Induction of Adipogenesis by External Volume Expansion. Plast Reconstr Surg. 2016 Oct; 138(4):770e-2e. PMID: 27307329.
      View in: PubMed
    33. Matsumine H, Numakura K, Climov M, Watanabe Y, Giatsidis G, Orgill DP. Facial-nerve regeneration ability of a hybrid artificial nerve conduit containing uncultured adipose-derived stromal vascular fraction: An experimental study. Microsurgery. 2017 Oct; 37(7):808-818. PMID: 27273726.
      View in: PubMed
    34. Icli B, Nabzdyk CS, Lujan-Hernandez J, Cahill M, Auster ME, Wara AK, Sun X, Ozdemir D, Giatsidis G, Orgill DP, Feinberg MW. Regulation of impaired angiogenesis in diabetic dermal wound healing by microRNA-26a. J Mol Cell Cardiol. 2016 Feb; 91:151-9. PMID: 26776318.
      View in: PubMed
    35. Atzori M, Gijsberts A, Castellini C, Caputo B, Hager AG, Elsig S, Giatsidis G, Bassetto F, Müller H. Effect of clinical parameters on the control of myoelectric robotic prosthetic hands. J Rehabil Res Dev. 2016; 53(3):345-58. PMID: 27272750.
      View in: PubMed
    36. Lujan-Hernandez J, Lancerotto L, Nabzdyk C, Hassan KZ, Giatsidis G, Khouri RK, Chin MS, Bassetto F, Lalikos JF, Orgill DP. Induction of Adipogenesis by External Volume Expansion. Plast Reconstr Surg. 2016 Jan; 137(1):122-31. PMID: 26710016.
      View in: PubMed
    37. Atzori M, Hager AG, Elsig S, Giatsidis G, Bassetto F, Muller H. Effects of prosthesis use on the capability to control myoelectric robotic prosthetic hands. Conf Proc IEEE Eng Med Biol Soc. 2015 Aug; 2015:3456-9. PMID: 26737036.
      View in: PubMed
    38. Pontini A, Reho F, Giatsidis G, Bacci C, Azzena B, Tiengo C. Multidisciplinary care in severe pediatric electrical oral burn. Burns. 2015 May; 41(3):e41-6. PMID: 25716757.
      View in: PubMed
    39. Vindigni V, Giatsidis G, Berlanda G, Bassetto F. Response to "Avoiding tension of wound closure in reduction mammaplasty and mastopexy in previously irradiated breasts". Aesthet Surg J. 2015 Jan; 35(1):NP14-5. PMID: 25568250.
      View in: PubMed
    40. Atzori M, Gijsberts A, Castellini C, Caputo B, Hager AG, Elsig S, Giatsidis G, Bassetto F, Müller H. Electromyography data for non-invasive naturally-controlled robotic hand prostheses. Sci Data. 2014; 1:140053. PMID: 25977804.
      View in: PubMed
    41. Sartore L, Venezia ED, Della Puppa A, Bedogni A, Campana L, Giatsidis G. Reconstructive strategies for dermatofibrosarcomas of the face: role of regenerative dermal templates. Head Neck. 2015 Jan; 37(1):E8-11. PMID: 24816728.
      View in: PubMed
    42. Vindigni V, Giatsidis G, Tiengo C, Sartore L, Schiavon M, Bassetto F. Reduction mammaplasty and mastopexy in previously irradiated breasts: notes on safety and pitfalls. Aesthet Surg J. 2014 May 01; 34(4):636-7. PMID: 24755418.
      View in: PubMed
    43. Tiengo C, Giatsidis G, Azzena B. Fascia lata allografts as biological mesh in abdominal wall repair: preliminary outcomes from a retrospective case series. Plast Reconstr Surg. 2013 Oct; 132(4):631e-639e. PMID: 24076711.
      View in: PubMed
    44. Semplicini A, Vindigni V, Giatsidis G, Chiarelli A. Padova Hospitale Onlus: report of a 15-year experience in surgical and medical assistance in developing countries. Ann Plast Surg. 2013 Jul; 71(1):6-9. PMID: 23241761.
      View in: PubMed
    45. Giatsidis G, Dalla Venezia E, Bassetto F. The role of gene therapy in regenerative surgery: updated insights. Plast Reconstr Surg. 2013 Jun; 131(6):1425-35. PMID: 23714802.
      View in: PubMed
    46. Giatsidis G, Vindigni V. Observations on the survival and neovascularization of fat grafts interchanged between C57BL/6-gfp and C57BL/6 mice. Plast Reconstr Surg. 2013 Apr; 131(4):644e-5e. PMID: 23542288.
      View in: PubMed
    47. Chiarelli A, Bassetto F, Giatsidis G, Vindigni V. Synthetic hair implantation and squamous cell carcinoma of the scalp. Aesthetic Plast Surg. 2013 Apr; 37(2):482. PMID: 23435507.
      View in: PubMed
    48. Giatsidis G, Giatsidis F, Bassetto F. Neurological picture. Unilateral carpal tunnel syndrome secondary to lipomatosis of the median nerve. J Neurol Neurosurg Psychiatry. 2013 Mar; 84(3):362. PMID: 23138767.
      View in: PubMed
    49. Sartore L, Tiengo C, Reho F, Giatsidis G. Pediatric digital replantations: regenerative dermis in a salvage procedure. Plast Reconstr Surg. 2012 Aug; 130(2):387e-389e. PMID: 22842453.
      View in: PubMed
    50. Chiarelli A, Rotilio A, De Min V, Chiarion-Sileni V, Giatsidis G, Sartore L, Bassetto F, Vindigni V. A case of squamous cell carcinoma of the scalp after several synthetic hair grafts. Aesthetic Plast Surg. 2012 Jun; 36(3):649-52. PMID: 22361957.
      View in: PubMed
    51. Sartore L, Giatsidis G, Reho F, Tanzillo G, Campana L, Salmaso R. Ear melanoma: influence of perichondrium involvement in evaluating surgical strategy. Eur Arch Otorhinolaryngol. 2012 Jun; 269(6):1685-90. PMID: 22081097.
      View in: PubMed
    52. Sartore L, Lancerotto L, Salmaso M, Giatsidis G, Paccagnella O, Alaibac M, Bassetto F. Facial basal cell carcinoma: analysis of recurrence and follow-up strategies. Oncol Rep. 2011 Dec; 26(6):1423-9. PMID: 21922143.
      View in: PubMed
    53. Vindigni V, Pajardi G, Lancerotto L, Giatsidis G, Salmaso R, Abatangelo G, Bassetto F. Negative pressure therapy potential enhancement with a biointeractive hyaluronan acid scaffold interface: case report. Dermatol Surg. 2011 Apr; 37(4):543-6. PMID: 21414075.
      View in: PubMed
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