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Raul Alejandro Padron Crema PhD

TitleProfessor
InstitutionUMass Chan Medical School
DepartmentRadiology
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
Phone508-856-1675 x61675
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentRadiology


    Collapse Biography 
    Collapse education and training
    Central University of Venezuela, Caracas, , VenezuelaBSEngineering
    MRC Laboratory of Molecular Biology, Cambridge, U.K.Postdoctoral Fellow
    Venezuelan Institute for Science Research -Caracas, Caracas, , VenezuelaMSBiology
    Venezuelan Institute for Science Research -Caracas, Caracas, , VenezuelaDR.SBiology
    Collapse awards and honors
    2018Elected International Member, National Academy of Sciences (NAS) U.S.A.
    2004Elected Member, The World Academy of Sciences (TWAS)
    2002Elected Member, Latin American Academy of Sciences (ACAL)

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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Viswanathan MC, Dutta D, Kronert WA, Chitre K, Padr?n R, Craig R, Bernstein SI, Cammarato A. Dominant myosin storage myopathy mutations disrupt striated muscles in Drosophila and the myosin tail-tail interactome of human cardiac thick filaments. Genetics. 2025 Jan 08; 229(1):1-34. PMID: 39485824.
      Citations:    
    2. Dutta D, Nguyen V, Campbell KS, Padr?n R, Craig R. Cryo-EM structure of the human cardiac myosin filament. bioRxiv. 2023 Apr 12. PMID: 37090534.
      Citations:    
    3. Padr?n R, Dutta D, Craig R. Variants of the myosin interacting-heads motif. J Gen Physiol. 2023 01 02; 155(1). PMID: 36346431.
      Citations: 3     Fields:    
    4. Koubassova NA, Tsaturyan AK, Bershitsky SY, Ferenczi MA, Padr?n R, Craig R. Interacting-heads motif explains the X-ray diffraction pattern of relaxed vertebrate skeletal muscle. Biophys J. 2022 04 19; 121(8):1354-1366. PMID: 35318005.
      Citations: 4     Fields:    Translation:AnimalsCells
    5. Craig R, Padrón R. . 2022 Jan 3;154(1). doi: 10.1085/jgp.202113012. Epub 2021 Dec 10. PubMed PMID: 34889960; PubMed Central PMCID: PMC8669498. Structural basis of the super- and hyper-relaxed states of myosin II. J Gen Physiol. 2022; 154(1). View Publication.
    6. Weikang Ma, Sebastian Duno-Miranda, Thomas Irving, Roger Craig, and Raul Padron. Relaxed tarantula skeletal muscle has two ATP energy-saving mechanisms. J Gen Physiology. 2021; 153(3):e202012780. View Publication.
    7. Yang S, Tiwari P, Lee KH, Sato O, Ikebe M, Padr?n R, Craig R. Cryo-EM structure of the inhibited (10S) form of myosin II. Nature. 2020 12; 588(7838):521-525. PMID: 33268893.
      Citations: 28     Fields:    Translation:AnimalsCells
    8. Padr?n R, Ma W, Duno-Miranda S, Koubassova N, Lee KH, Pinto A, Alamo L, Bola?os P, Tsaturyan A, Irving T, Craig R. The myosin interacting-heads motif present in live tarantula muscle explains tetanic and posttetanic phosphorylation mechanisms. Proc Natl Acad Sci U S A. 2020 06 02; 117(22):11865-11874. PMID: 32444484.
      Citations: 25     Fields:    Translation:AnimalsCells
    9. Padrón, R., Ma, W., Duno-Miranda, S., Koubassova, N., Lee, K. H., Pinto, A., Alamo, L., Bolaños, P., Tsaturyan, A., Irving, T. and Craig, R. . The myosin interacting-heads motif present in live tarantula muscle explains tetanic and post-tetanic phosphorylation mechanisms. Proceedings of the National Academy of Sciences May 2020, 201921312; DOI: 10.1073/pnas.1921312117. 2020. View Publication.
    10. Toepfer CN, Garfinkel AC, Venturini G, Wakimoto H, Repetti G, Alamo L, Sharma A, Agarwal R, Ewoldt JF, Cloonan P, Letendre J, Lun M, Olivotto I, Colan S, Ashley E, Jacoby D, Michels M, Redwood CS, Watkins HC, Day SM, Staples JF, Padrón R, Chopra A, Ho CY, Chen CS, Pereira AC, Seidman JG, Seidman CE. Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy. Circulation . 2020. View Publication.
    11. Sulbarán G, Biasutto A, Méndez F, Pinto A, Alamo L, Padrón R. . 18O labeling on Ser45 but not on Ser35 supports the cooperative phosphorylation mechanism on tarantula thick filament activation. Biochem Biophys Res Commun. 2020. View Publication.
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