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John Charles McCann MD

TitleAssistant Professor
InstitutionUMass Chan – Baystate Regional Campus
DepartmentMedicine at UMass Chan - Baystate
AddressBaystate Health Regional Campus
759 Chestnut Street
Springfield MA 01199
Phone413-794-9338
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    Collapse Biography 
    Collapse education and training
    Swarthmore College, Swarthmore, PA, United StatesBA
    University of Massachusetts Medical School, Worcester, MA, United StatesMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ramalingam SS, Dahlberg SE, Belani CP, Saltzman JN, Pennell NA, Nambudiri GS, McCann JC, Winegarden JD, Kassem MA, Mohamed MK, Rothman JM, Lyss AP, Horn L, Stinchcombe TE, Schiller JH. Pemetrexed, Bevacizumab, or the Combination As Maintenance Therapy for Advanced Nonsquamous Non-Small-Cell Lung Cancer: ECOG-ACRIN 5508. J Clin Oncol. 2019 09 10; 37(26):2360-2367. PMID: 31361535.
      Citations: 19     Fields:    Translation:Humans
    2. Lin EP, Miles L, Hughes EA, McCann JC, Vorhees CV, McAuliffe JJ, Loepke AW. A combination of mild hypothermia and sevoflurane affords long-term protection in a modified neonatal mouse model of cerebral hypoxia-ischemia. Anesth Analg. 2014 Nov; 119(5):1158-73. PMID: 24878681.
      Citations: 7     Fields:    Translation:Animals
    3. Istaphanous GK, Ward CG, Nan X, Hughes EA, McCann JC, McAuliffe JJ, Danzer SC, Loepke AW. Characterization and quantification of isoflurane-induced developmental apoptotic cell death in mouse cerebral cortex. Anesth Analg. 2013 Apr; 116(4):845-54. PMID: 23460572.
      Citations: 33     Fields:    Translation:AnimalsCells
    4. Istaphanous GK, Howard J, Nan X, Hughes EA, McCann JC, McAuliffe JJ, Danzer SC, Loepke AW. Comparison of the neuroapoptotic properties of equipotent anesthetic concentrations of desflurane, isoflurane, or sevoflurane in neonatal mice. Anesthesiology. 2011 Mar; 114(3):578-87. PMID: 21293251.
      Citations: 106     Fields:    Translation:AnimalsCells
    5. Kurth CD, McCann JC, Wu J, Miles L, Loepke AW. Cerebral oxygen saturation-time threshold for hypoxic-ischemic injury in piglets. Anesth Analg. 2009 Apr; 108(4):1268-77. PMID: 19299799.
      Citations: 18     Fields:    Translation:AnimalsCells
    6. Loepke AW, Istaphanous GK, McAuliffe JJ, Miles L, Hughes EA, McCann JC, Harlow KE, Kurth CD, Williams MT, Vorhees CV, Danzer SC. The effects of neonatal isoflurane exposure in mice on brain cell viability, adult behavior, learning, and memory. Anesth Analg. 2009 Jan; 108(1):90-104. PMID: 19095836.
      Citations: 98     Fields:    Translation:AnimalsCells
    7. Nelson LA, McCann JC, Loepke AW, Wu J, Ben Dor B, Kurth CD. Development and validation of a multiwavelength spatial domain near-infrared oximeter to detect cerebral hypoxia-ischemia. J Biomed Opt. 2006 Nov-Dec; 11(6):064022. PMID: 17212545.
      Citations: 5     Fields:    Translation:Animals
    8. Loepke AW, McCann JC, Kurth CD, McAuliffe JJ. The physiologic effects of isoflurane anesthesia in neonatal mice. Anesth Analg. 2006 Jan; 102(1):75-80. PMID: 16368807.
      Citations: 30     Fields:    Translation:Animals
    9. Loepke AW, Golden JA, McCann JC, Kurth CD. Injury pattern of the neonatal brain after hypothermic low-flow cardiopulmonary bypass in a piglet model. Anesth Analg. 2005 Aug; 101(2):340-348. PMID: 16037141.
      Citations: 2     Fields:    Translation:Animals
    10. Nugent FW, Mertens WC, Graziano S, Levitan N, Collea R, Gajra A, Marshall J, McCann J. Docetaxel and cyclooxygenase-2 inhibition with celecoxib for advanced non-small cell lung cancer progressing after platinum-based chemotherapy: a multicenter phase II trial. Lung Cancer. 2005 May; 48(2):267-73. PMID: 15829328.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    11. Ditsworth D, Priestley MA, Loepke AW, Ramamoorthy C, McCann J, Staple L, Kurth CD. Apoptotic neuronal death following deep hypothermic circulatory arrest in piglets. Anesthesiology. 2003 May; 98(5):1119-27. PMID: 12717133.
      Citations: 11     Fields:    Translation:AnimalsCells
    12. Loepke AW, Priestley MA, Schultz SE, McCann J, Golden J, Kurth CD. Desflurane improves neurologic outcome after low-flow cardiopulmonary bypass in newborn pigs. Anesthesiology. 2002 Dec; 97(6):1521-7. PMID: 12459680.
      Citations: 8     Fields:    Translation:Animals
    13. Kurth CD, Levy WJ, McCann J. Near-infrared spectroscopy cerebral oxygen saturation thresholds for hypoxia-ischemia in piglets. J Cereb Blood Flow Metab. 2002 Mar; 22(3):335-41. PMID: 11891439.
      Citations: 40     Fields:    Translation:Animals
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