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Eric Chi Ching Ko MD, PhD

TitleAssociate Professor
InstitutionUMass Chan Medical School
DepartmentRadiation Oncology
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
Phone774-442-5551
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentRadiation Oncology

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentCancer Biology


    Collapse Biography 
    Collapse education and training
    Yale University, New Haven, CT, United StatesBS
    Roswell Park Cancer Institute, Buffalo, NY, United StatesPHD
    University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, United StatesMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ko EC, Hanna GJ. Immunotherapy for head and neck cancer: where do we go from here? Immunotherapy. 2023 Dec; 15(18):1497-1500. PMID: 38009225.
      Citations:    Fields:    Translation:Humans
    2. Shen JL, O'Connor KW, Moni J, Zweizig S, Fitzgerald TJ, Ko EC. Definitive Radiation Therapy for Medically Inoperable Endometrial Carcinoma. Adv Radiat Oncol. 2023 Jan-Feb; 8(1):101003. PMID: 36711065.
      Citations:    
    3. Shen JL, Ko EC. Stereotactic body radiation therapy for metastatic non-small cell lung cancer: a versatile treatment, repurposed. J Thorac Dis. 2022 Jul; 14(7):2443-2446. PMID: 35928605.
      Citations:    
    4. Agrawal V, Benjamin KT, Ko EC. Radiotherapy and Immunotherapy Combinations for Lung Cancer. Curr Oncol Rep. 2020 11 19; 23(1):4. PMID: 33215306.
      Citations: 7     Fields:    Translation:Humans
    5. Ko EC, Vanpouille-Box C, Formenti SC. Analysis of Pathologic Complete Response 10 Weeks After Radiotherapy-A Radiobiological Sin. JAMA Oncol. 2019 Sep 01; 5(9):1365. PMID: 31268473.
      Citations:    Fields:    
    6. Ko EC, Formenti SC. Radiation therapy to enhance tumor immunotherapy: a novel application for an established modality. Int J Radiat Biol. 2019 07; 95(7):936-939. PMID: 31120369.
      Citations: 32     Fields:    Translation:HumansCells
    7. Ko EC, Galluzzi L. Radiation unlocks the therapeutic potential of immune checkpoint blockers in lung cancer patients. Oncoimmunology. 2019; 8(8):1606624. PMID: 31413913.
      Citations: 1     Fields:    
    8. Ko EC, Benjamin KT, Formenti SC. Generating antitumor immunity by targeted radiation therapy: Role of dose and fractionation. Adv Radiat Oncol. 2018 Oct-Dec; 3(4):486-493. PMID: 30370347.
      Citations:    
    9. Ko E. Eric Ko on Combining Radiation Therapy With Immunotherapy to Treat Non-Small-Cell Lung Cancer. Oncology (Williston Park). 2018 09 15; 32(9):460-2. PMID: 30248167.
      Citations:    Fields:    Translation:Humans
    10. Ko EC, Raben D, Formenti SC. The Integration of Radiotherapy with Immunotherapy for the Treatment of Non-Small Cell Lung Cancer. Clin Cancer Res. 2018 12 01; 24(23):5792-5806. PMID: 29945993.
      Citations: 127     Fields:    Translation:Humans
    11. Ko EC, Formenti SC. Radiotherapy and checkpoint inhibitors: a winning new combination? Ther Adv Med Oncol. 2018; 10:1758835918768240. PMID: 29662550.
      Citations:    
    12. Valicenti RK, Pugh SL, Trabulsi EJ, Sartor O, Ko EC, Girvigian MR, Rosenthal SA, Shaves ME, Hoffman-Censits JH, Schallenkamp J, Sandler HM. First Report of NRG Oncology/Radiation Therapy Oncology Group 0622: A Phase 2 Trial of Samarium-153 Followed by Salvage Prostatic Fossa Irradiation in High-Risk Clinically Nonmetastatic Prostate Cancer After Radical Prostatectomy. Int J Radiat Oncol Biol Phys. 2018 03 01; 100(3):695-701. PMID: 29413282.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    13. Wei XX, Ko EC, Ryan CJ. Treatment strategies in low-volume metastatic castration-resistant prostate cancer. Curr Opin Urol. 2017 Nov; 27(6):596-603. PMID: 28786849.
      Citations: 7     Fields:    Translation:Humans
    14. Ko EC, Michaud AL, Valicenti RK. Postoperative Radiation After Radical Prostatectomy. Semin Radiat Oncol. 2017 01; 27(1):50-66. PMID: 27986212.
      Citations: 1     Fields:    Translation:Humans
    15. Chen HM, Ma G, Gildener-Leapman N, Eisenstein S, Coakley BA, Ozao J, Mandeli J, Divino C, Schwartz M, Sung M, Ferris R, Kao J, Wang LH, Pan PY, Ko EC, Chen SH. Myeloid-Derived Suppressor Cells as an Immune Parameter in Patients with Concurrent Sunitinib and Stereotactic Body Radiotherapy. Clin Cancer Res. 2015 Sep 15; 21(18):4073-4085. PMID: 25922428.
      Citations: 62     Fields:    Translation:HumansCellsCTClinical Trials
    16. Carpenter TJ, Kann B, Buckstein MH, Ko EC, Bakst RL, Misiukiewicz KJ, Posner MR, Genden EM, Gupta V. Tolerability, toxicity, and temporal implications of transoral robotic surgery (TORS) on adjuvant radiation therapy in carcinoma of the head and neck. Ann Otol Rhinol Laryngol. 2014 Nov; 123(11):791-7. PMID: 24847162.
      Citations: 4     Fields:    Translation:Humans
    17. D'souza G, Carey TE, William WN, Nguyen ML, Ko EC, Riddell J, Pai SI, Gupta V, Walline HM, Lee JJ, Wolf GT, Shin DM, Grandis JR, Ferris RL. Epidemiology of head and neck squamous cell cancer among HIV-infected patients. J Acquir Immune Defic Syndr. 2014 Apr 15; 65(5):603-10. PMID: 24326607.
      Citations: 33     Fields:    Translation:Humans
    18. Ko EC, Liu JT, Stone NN, Stock RG. Association of early PSA failure time with increased distant metastasis and decreased survival in prostate brachytherapy patients. Radiother Oncol. 2014 Feb; 110(2):261-7. PMID: 24299969.
      Citations: 1     Fields:    Translation:Humans
    19. Fu S, Yang Y, Das TK, Tirtha D, Yen Y, Zhou BS, Zhou MM, Ohlmeyer M, Ko EC, Cagan R, Rosenstein BS, Chen SH, Kao J. ?-H2AX kinetics as a novel approach to high content screening for small molecule radiosensitizers. PLoS One. 2012; 7(6):e38465. PMID: 22768044.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    20. Tong CC, Ko EC, Sung MW, Cesaretti JA, Stock RG, Packer SH, Forsythe K, Genden EM, Schwartz M, Lau KH, Galsky M, Ozao-Choy J, Chen SH, Kao J. Phase II trial of concurrent sunitinib and image-guided radiotherapy for oligometastases. PLoS One. 2012; 7(6):e36979. PMID: 22761653.
      Citations: 27     Fields:    Translation:HumansCTClinical Trials
    21. Tong CC, Lau KH, Rivera M, Cannan D, Aguirre-Ghiso J, Sikora AG, Gupta V, Forsythe K, Ko EC, Misiukiewicz K, Gurudutt V, Teng MS, Packer SH, Genden EM, Kao J. Prognostic significance of p16 in locoregionally advanced head and neck cancer treated with concurrent 5-fluorouracil, hydroxyurea, cetuximab and intensity-modulated radiation therapy. Oncol Rep. 2012 May; 27(5):1580-6. PMID: 22322320.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    22. Ko EC, Genden EM, Misiukiewicz K, Som PM, Kostakoglu L, Chen CT, Packer S, Kao J. Toxicity profile and clinical outcomes in locally advanced head and neck cancer patients treated with induction chemotherapy prior to concurrent chemoradiation. Oncol Rep. 2012 Feb; 27(2):467-74. PMID: 22020564.
      Citations: 8     Fields:    Translation:Humans
    23. Fu S, Rivera M, Ko EC, Sikora AG, Chen CT, Vu HL, Cannan D, Eisenstein S, Rosenstein BS, Aguirre-Ghiso J, Chen SH, Kao J. Combined Inhibition of Epidermal Growth Factor Receptor and Cyclooxygenase-2 as a Novel Approach to Enhance Radiotherapy. J Cell Sci Ther. 2011 Oct 13; 1(2). PMID: 23483082.
      Citations:    
    24. Ko EC, Stone NN, Stock RG. PSA nadir of <0.5 ng/mL following brachytherapy for early-stage prostate adenocarcinoma is associated with freedom from prostate-specific antigen failure. Int J Radiat Oncol Biol Phys. 2012 Jun 01; 83(2):600-7. PMID: 21985944.
      Citations: 14     Fields:    Translation:Humans
    25. Kao J, Ko EC, Eisenstein S, Sikora AG, Fu S, Chen SH. Targeting immune suppressing myeloid-derived suppressor cells in oncology. Crit Rev Oncol Hematol. 2011 Jan; 77(1):12-9. PMID: 20304669.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    26. Ko EC, Koprowski CD, Dickson-Witmer D, Penman E, Sorensen M, Hanlon AL, Sammons S, Farach A, Strasser J. Partial vs. whole breast irradiation in a community hospital: a retrospective cohort analysis of 200 patients. Brachytherapy. 2010 Jul-Sep; 9(3):248-53. PMID: 20153984.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    27. Ko E, Luo W, Peng L, Wang X, Ferrone S. Mouse dendritic-endothelial cell hybrids and 4-1BB costimulation elicit antitumor effects mediated by broad antiangiogenic immunity. Cancer Res. 2007 Aug 15; 67(16):7875-84. PMID: 17699794.
      Citations: 9     Fields:    Translation:AnimalsCells
    28. Luo W, Ko E, Hsu JC, Wang X, Ferrone S. Targeting melanoma cells with human high molecular weight-melanoma associated antigen-specific antibodies elicited by a peptide mimotope: functional effects. J Immunol. 2006 May 15; 176(10):6046-54. PMID: 16670313.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    29. Peng L, Ko E, Luo W, Wang X, Shrikant PA, Ferrone S. CD4-dependent potentiation of a high molecular weight-melanoma-associated antigen-specific CTL response elicited in HLA-A2/Kb transgenic mice. J Immunol. 2006 Feb 15; 176(4):2307-15. PMID: 16455987.
      Citations: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    30. Wang X, Ko EC, Peng L, Gillies SD, Ferrone S. Human high molecular weight melanoma-associated antigen mimicry by mouse anti-idiotypic monoclonal antibody MK2-23: enhancement of immunogenicity of anti-idiotypic monoclonal antibody MK2-23 by fusion with interleukin 2. Cancer Res. 2005 Aug 01; 65(15):6976-83. PMID: 16061683.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    31. Luo W, Hsu JC, Tsao CY, Ko E, Wang X, Ferrone S. Differential immunogenicity of two peptides isolated by high molecular weight-melanoma-associated antigen-specific monoclonal antibodies with different affinities. J Immunol. 2005 Jun 01; 174(11):7104-10. PMID: 15905554.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    32. Wang X, Campoli M, Ko E, Luo W, Ferrone S. Enhancement of scFv fragment reactivity with target antigens in binding assays following mixing with anti-tag monoclonal antibodies. J Immunol Methods. 2004 Nov; 294(1-2):23-35. PMID: 15604013.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    33. Ko EC, Wang X, Ferrone S. Immunotherapy of malignant diseases. Challenges and strategies. Int Arch Allergy Immunol. 2003 Dec; 132(4):294-309. PMID: 14707461.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
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