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Connection

Fiachra Humphries to Animals

This is a "connection" page, showing publications Fiachra Humphries has written about Animals.
Connection Strength

0.772
  1. Humphries F. Misfirin' pyrin. Sci Immunol. 2026 08 07; 11(122):eaei8902.
    View in: PubMed
    Score: 0.068
  2. Cahill S, Humphries F. Measurement and quantification of macrophage lytic cell death by kinetic microscopy. Methods Cell Biol. 2026; 206:109-122.
    View in: PubMed
    Score: 0.066
  3. Stine LB, Humphries F. Measurement of plasma membrane rupture via confocal microscopy. Methods Cell Biol. 2026; 205:47-62.
    View in: PubMed
    Score: 0.065
  4. Shmuel-Galia L, Jiang Z, Stine L, Cahill S, Ng SL, Wilson R, Kandasamy RK, Kurt-Jones EA, Ramanjulu JM, Bertin J, Kasparcova V, Pesiridis GS, Fitzgerald KA, Humphries F. Alternative cGAS signaling promotes herpes simplex encephalitis. Proc Natl Acad Sci U S A. 2025 Jun 03; 122(22):e2423873122.
    View in: PubMed
    Score: 0.062
  5. Cahill S, Humphries F. Inflammasomopathies: mechanisms and disease signatures. Trends Immunol. 2025 05; 46(5):372-385.
    View in: PubMed
    Score: 0.062
  6. Yang S, Humphries F. Emerging roles of ECSIT in immunity and tumorigenesis. Trends Cell Biol. 2025 May; 35(5):426-438.
    View in: PubMed
    Score: 0.060
  7. Stine L, Humphries F. Gasdermin D palmitoylation: to cleave or not to cleave? Trends Immunol. 2024 06; 45(6):403-405.
    View in: PubMed
    Score: 0.058
  8. Humphries F. cGAS-like receptors: back to the future. Trends Immunol. 2023 10; 44(10):760-762.
    View in: PubMed
    Score: 0.056
  9. Humphries F, Shmuel-Galia L, Jiang Z, Zhou JY, Barasa L, Mondal S, Wilson R, Sultana N, Shaffer SA, Ng SL, Pesiridis GS, Thompson PR, Fitzgerald KA. Targeting STING oligomerization with small-molecule inhibitors. Proc Natl Acad Sci U S A. 2023 08 15; 120(33):e2305420120.
    View in: PubMed
    Score: 0.055
  10. Humphries F, Fitzgerald KA. Igniting the firestorm: The inflammasome in autoinflammatory syndromes. J Allergy Clin Immunol. 2021 12; 148(6):1470-1472.
    View in: PubMed
    Score: 0.048
  11. Humphries F, Shmuel-Galia L, Ketelut-Carneiro N, Li S, Wang B, Nemmara VV, Wilson R, Jiang Z, Khalighinejad F, Muneeruddin K, Shaffer SA, Dutta R, Ionete C, Pesiridis S, Yang S, Thompson PR, Fitzgerald KA. Succination inactivates gasdermin D and blocks pyroptosis. Science. 2020 09 25; 369(6511):1633-1637.
    View in: PubMed
    Score: 0.045
  12. Barasa L, DeOrsey L, O'Reilly MD, Choudhary S, Cahill SE, Mathur A, Allabaji A, Nellikkalaya S, Paul S, Vidadala SR, Sarkar SK, Rajendran M, Patil SN, Kalonia H, Hale J, Humphries F, Fitzgerald KA, Thompson PR. Development of UM-200: A Novel Alkyne Amide-Based Inhibitor of the cGAS-STING Pathway. J Med Chem. 2026 Apr 09; 69(7):8561-8582.
    View in: PubMed
    Score: 0.017
  13. Golonka RM, Intravaia LE, Shaqra AM, Li Q, Chen Y, Humphries F, Kurt-Yilmaz N, Fitzgerald KA, Schiffer CA, Wang Y, Cavacini LA. Engineered IgA-Fc fusion protein with bioactive nanobody neutralizes SARS-CoV-2 variants with mucosal delivery potential. J Biol Chem. 2026 Mar; 302(3):111210.
    View in: PubMed
    Score: 0.016
  14. Tse-Kang SY, Wani KA, Peterson ND, Page A, Humphries F, Pukkila-Worley R. Intestinal immunity in C.?elegans is activated by pathogen effector-triggered aggregation of the guard protein TIR-1 on lysosome-related organelles. Immunity. 2024 10 08; 57(10):2280-2295.e6.
    View in: PubMed
    Score: 0.015
  15. Chen Y, Lei X, Jiang Z, Humphries F, Parsi KM, Mustone NJ, Ramos I, Mutetwa T, Fernandez-Sesma A, Maehr R, Caffrey DR, Fitzgerald KA. Cellular nucleic acid-binding protein restricts SARS-CoV-2 by regulating interferon and disrupting RNA-protein condensates. Proc Natl Acad Sci U S A. 2023 11 21; 120(47):e2308355120.
    View in: PubMed
    Score: 0.014
  16. Shmuel-Galia L, Humphries F, Vierbuchen T, Jiang Z, Santos N, Johnson J, Shklyar B, Joannas L, Mustone N, Sherman S, Ward D, Houghton J, Baer CE, O'Hara A, Henao-Mejia J, Hoebe K, Fitzgerald KA. The lncRNA HOXA11os regulates mitochondrial function in myeloid cells to maintain intestinal homeostasis. Cell Metab. 2023 08 08; 35(8):1441-1456.e9.
    View in: PubMed
    Score: 0.014
  17. Sciaudone A, Corkrey H, Humphries F, Koupenova M. Platelets and SARS-CoV-2 During COVID-19: Immunity, Thrombosis, and Beyond. Circ Res. 2023 05 12; 132(10):1272-1289.
    View in: PubMed
    Score: 0.014
  18. Hariharan VN, Shin M, Chang CW, O'Reilly D, Biscans A, Yamada K, Guo Z, Somasundaran M, Tang Q, Monopoli K, Krishnamurthy PM, Devi G, McHugh N, Cooper DA, Echeverria D, Cruz J, Chan IL, Liu P, Lim SY, McConnell J, Singh SP, Hildebrand S, Sousa J, Davis SM, Kennedy Z, Ferguson C, Godinho BMDC, Thillier Y, Caiazzi J, Ly S, Muhuri M, Kelly K, Humphries F, Cousineau A, Parsi KM, Li Q, Wang Y, Maehr R, Gao G, Korkin D, McDougall WM, Finberg RW, Fitzgerald KA, Wang JP, Watts JK, Khvorova A. Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection. Proc Natl Acad Sci U S A. 2023 03 14; 120(11):e2219523120.
    View in: PubMed
    Score: 0.013
  19. Li Q, Humphries F, Girardin RC, Wallace A, Ejemel M, Amcheslavsky A, McMahon CT, Schiller ZA, Ma Z, Cruz J, Dupuis AP, Payne AF, Maryam A, Yilmaz NK, McDonough KA, Pierce BG, Schiffer CA, Kruse AC, Klempner MS, Cavacini LA, Fitzgerald KA, Wang Y. Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants. Front Immunol. 2022; 13:995412.
    View in: PubMed
    Score: 0.013
  20. Shmuel-Galia L, Humphries F, Lei X, Ceglia S, Wilson R, Jiang Z, Ketelut-Carneiro N, Foley SE, Pechhold S, Houghton J, Muneeruddin K, Shaffer SA, McCormick BA, Reboldi A, Ward D, Marshak-Rothstein A, Fitzgerald KA. Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells. Immunity. 2021 06 08; 54(6):1137-1153.e8.
    View in: PubMed
    Score: 0.012
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.