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Rebecca J Shipley MD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentEmergency Medicine
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01605
Phone508-421-1400
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentEmergency Medicine


    Collapse Biography 
    Collapse education and training
    Georgetown University, Washington, DC, United StatesBSInternational Health
    Emory University, Atlanta, GA, United StatesMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Laranjeira S, Guillemot-Legris O, Girmahun G, Phillips JB, Shipley RJ. Open-source software to calculate the static sciatic index automatically. Regen Med. 2025 Feb-Mar; 20(2-3):77-85. PMID: 40099847.
      Citations:    
    2. Brown EE, Guy AA, Holroyd NA, Sweeney PW, Gourmet L, Coleman H, Walsh C, Markaki AE, Shipley R, Rajendram R, Walker-Samuel S. Author Correction: Physics-informed deep generative learning for quantitative assessment of the retina. Nat Commun. 2025 Feb 13; 16(1):1606. PMID: 39948098.
      Citations:    
    3. Doman EA, Ovenden NC, Phillips JB, Shipley RJ. Biomechanical modelling infers that collagen content within peripheral nerves is a greater indicator of axial Young's modulus than structure. Biomech Model Mechanobiol. 2025 Feb; 24(1):297-309. PMID: 39585529.
      Citations:    
    4. de Oliveira DC, Cheikh Sleiman H, Payette K, Hutter J, Story L, Hajnal JV, Alexander DC, Shipley RJ, Slator PJ. A flexible generative algorithm for growing in silico placentas. PLoS Comput Biol. 2024 Oct; 20(10):e1012470. PMID: 39374295.
      Citations:    
    5. Laranjeira S, Guillemot-Legris O, Girmahun G, Roberton V, Phillips JB, Shipley RJ. In silico model for automated calculation of functional metrics in animal models of peripheral nerve injury repair. Comput Biol Med. 2024 Oct; 181:109036. PMID: 39213706.
      Citations:    
    6. Brown EE, Guy AA, Holroyd NA, Sweeney PW, Gourmet L, Coleman H, Walsh C, Markaki AE, Shipley R, Rajendram R, Walker-Samuel S. Physics-informed deep generative learning for quantitative assessment of the retina. Nat Commun. 2024 Aug 10; 15(1):6859. PMID: 39127778.
      Citations:    
    7. Rahmani S, Jafree DJ, Lee PD, Tafforeau P, Brunet J, Nandanwar S, Jacob J, Bellier A, Ackermann M, Jonigk DD, Shipley RJ, Long DA, Walsh CL. Mapping the blood vasculature in an intact human kidney using hierarchical phase-contrast tomography. bioRxiv. 2024 Jul 05. PMID: 37034801.
      Citations:    
    8. Sweeney PW, Walsh C, Walker-Samuel S, Shipley RJ. A three-dimensional, discrete-continuum model of blood pressure in microvascular networks. Int J Numer Method Biomed Eng. 2024 Aug; 40(8):e3832. PMID: 38770788.
      Citations:    
    9. Al-Badri G, Phillips JB, Shipley RJ, Ovenden NC. Formation of vascular-like structures using a chemotaxis-driven multiphase model. Math Biosci. 2024 Jun; 372:109183. PMID: 38554855.
      Citations:    
    10. Grigorian G, George SV, Lishak S, Shipley RJ, Arridge S. A hybrid neural ordinary differential equation model of the cardiovascular system. J R Soc Interface. 2024 03; 21(212):20230710. PMID: 38503338.
      Citations:    
    11. Walsh CL, Berg M, West H, Holroyd NA, Walker-Samuel S, Shipley RJ. Reconstructing microvascular network skeletons from 3D images: What is the ground truth? Comput Biol Med. 2024 03; 171:108140. PMID: 38422956.
      Citations:    
    12. Lishak S, Grigorian G, George SV, Ovenden NC, Shipley RJ, Arridge S. A variable heart rate multi-compartmental coupled model of the cardiovascular and respiratory systems. J R Soc Interface. 2023 10; 20(207):20230339. PMID: 37848055.
      Citations:    Fields:    Translation:Humans
    13. Berg M, Eleftheriadou D, Phillips JB, Shipley RJ. Mathematical modelling with Bayesian inference to quantitatively characterize therapeutic cell behaviour in nerve tissue engineering. J R Soc Interface. 2023 09; 20(206):20230258. PMID: 37669694.
      Citations:    Fields:    
    14. Guillemot-Legris O, Girmahun G, Shipley RJ, Phillips JB. Local Administration of Minocycline Improves Nerve Regeneration in Two Rat Nerve Injury Models. Int J Mol Sci. 2023 Jul 28; 24(15). PMID: 37569473.
      Citations:    Fields:    
    15. Laranjeira S, Roberton VH, Phillips JB, Shipley RJ. Perspectives on optimizing local delivery of drugs to peripheral nerves using mathematical models. WIREs Mech Dis. 2023 03; 15(2):e1593. PMID: 36624330.
      Citations:    Fields:    Translation:Humans
    16. Eleftheriadou D, Berg M, Phillips JB, Shipley RJ. A combined experimental and computational framework to evaluate the behavior of therapeutic cells for peripheral nerve regeneration. Biotechnol Bioeng. 2022 07; 119(7):1980-1996. PMID: 35445744.
      Citations: 2     Fields:    
    17. Berg M, Holroyd N, Walsh C, West H, Walker-Samuel S, Shipley R. Challenges and opportunities of integrating imaging and mathematical modelling to interrogate biological processes. Int J Biochem Cell Biol. 2022 05; 146:106195. PMID: 35339913.
      Citations: 1     Fields:    Translation:Humans
    18. West H, Roberts F, Sweeney P, Walker-Samuel S, Leedale J, Colley H, Murdoch C, Shipley RJ, Webb S. A mathematical investigation into the uptake kinetics of nanoparticles in vitro. PLoS One. 2021; 16(7):e0254208. PMID: 34292999.
      Citations:    Fields:    Translation:HumansAnimals
    19. C?rcamo PM, Laca-Barrera M, Cabanillas-Silva D, M?laga-Rodr?guez G, Mallma-Salazar P, Moore D, Shipley R, Singer M, Garcia PJ. Feasibility of Noninvasive Positive Pressure Ventilation in the Treatment of Oxygen-Dependent COVID-19 Patients in Peru. Am J Trop Med Hyg. 2021 07 16; 105(3):727-730. PMID: 34270457.
      Citations: 1     Fields:    Translation:HumansCells
    20. Coy R, Berg M, Phillips JB, Shipley RJ. Modelling-informed cell-seeded nerve repair construct designs for treating peripheral nerve injuries. PLoS Comput Biol. 2021 07; 17(7):e1009142. PMID: 34237052.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    21. Lust ST, Hoogland D, Norman MDA, Kerins C, Omar J, Jowett GM, Yu TTL, Yan Z, Xu JZ, Marciano D, da Silva RMP, Dreiss CA, Lamata P, Shipley RJ, Gentleman E. Selectively Cross-Linked Tetra-PEG Hydrogels Provide Control over Mechanical Strength with Minimal Impact on Diffusivity. ACS Biomater Sci Eng. 2021 09 13; 7(9):4293-4304. PMID: 34151570.
      Citations: 7     Fields:    Translation:Cells
    22. Lust ST, Shanahan CM, Shipley RJ, Lamata P, Gentleman E. Design considerations for engineering 3D models to study vascular pathologies in vitro. Acta Biomater. 2021 09 15; 132:114-128. PMID: 33652164.
      Citations: 4     Fields:    Translation:HumansCells
    23. Shipley RJ, Brealey D, Haniffa R, Elwell C, Baker T, Lomas DA, Singer M. Lessons and risks of medical device deployment in a global pandemic. Lancet Glob Health. 2021 04; 9(4):e395-e396. PMID: 33548177.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    24. Singer M, Shipley R, Baker T, Brealey D, Lomas D. High oxygen flow rates with the UCL Ventura CPAP device - Authors' reply. Lancet Respir Med. 2021 04; 9(4):e36. PMID: 33545085.
      Citations: 1     Fields:    Translation:HumansCells
    25. Peters MJ, Shipley R. Clinical Classification of Cold and Warm Shock: Is There a Signal in the Noise? Pediatr Crit Care Med. 2020 12; 21(12):1085-1087. PMID: 33278214.
      Citations: 1     Fields:    Translation:Humans
    26. Singer M, Shipley R, Baker T, Cowell A, Brealey D, Lomas D. The UCL Ventura CPAP device for COVID-19. Lancet Respir Med. 2020 11; 8(11):1076-1078. PMID: 32971017.
      Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
    27. Nweze M, Baker T, Limb GA, Shipley RJ. Insights into the design of spray systems for cell therapies for retinal disease using computational modelling. Math Biosci Eng. 2020 03 11; 17(3):2741-2759. PMID: 32233564.
      Citations:    Fields:    Translation:Humans
    28. Shipley RJ, Smith AF, Sweeney PW, Pries AR, Secomb TW. A hybrid discrete-continuum approach for modelling microcirculatory blood flow. Math Med Biol. 2020 02 28; 37(1):40-57. PMID: 30892609.
      Citations: 9     Fields:    Translation:HumansAnimals
    29. Shipley RJ, Sweeney PW, Chapman SJ, Roose T. A four-compartment multiscale model of fluid and drug distribution in vascular tumours. Int J Numer Method Biomed Eng. 2020 03; 36(3):e3315. PMID: 32031302.
      Citations: 4     Fields:    Translation:Humans
    30. Kayal C, Moeendarbary E, Shipley RJ, Phillips JB. Mechanical Response of Neural Cells to Physiologically Relevant Stiffness Gradients. Adv Healthc Mater. 2020 04; 9(8):e1901036. PMID: 31793251.
      Citations: 17     Fields:    Translation:Cells
    31. Quan K, Tanno R, Shipley RJ, Brown JS, Jacob J, Hurst JR, Hawkes DJ. Reproducibility of an airway tapering measurement in computed tomography with application to bronchiectasis. J Med Imaging (Bellingham). 2019 Jul; 6(3):034003. PMID: 31548977.
      Citations:    
    32. Kayal C, Shipley RJ, Phillips JB. Physical and mechanical properties of RAFT-stabilised collagen gels for tissue engineering applications. J Mech Behav Biomed Mater. 2019 11; 99:216-224. PMID: 31394492.
      Citations: 4     Fields:    Translation:Animals
    33. Sweeney PW, d'Esposito A, Walker-Samuel S, Shipley RJ. Modelling the transport of fluid through heterogeneous, whole tumours in silico. PLoS Comput Biol. 2019 06; 15(6):e1006751. PMID: 31226169.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    34. Sorrell I, Shipley RJ, Regan S, Gardner I, Storm MP, Ellis M, Ward J, Williams D, Mistry P, Salazar JD, Scott A, Webb S. Mathematical modelling of a liver hollow fibre bioreactor. J Theor Biol. 2019 08 21; 475:25-33. PMID: 31100294.
      Citations:    Fields:    Translation:HumansAnimalsCells
    35. Burova I, Peticone C, De Silva Thompson D, Knowles JC, Wall I, Shipley RJ. A parameterised mathematical model to elucidate osteoblast cell growth in a phosphate-glass microcarrier culture. J Tissue Eng. 2019 Jan-Dec; 10:2041731419830264. PMID: 30858965.
      Citations:    
    36. Burova I, Wall I, Shipley RJ. Mathematical and computational models for bone tissue engineering in bioreactor systems. J Tissue Eng. 2019 Jan-Dec; 10:2041731419827922. PMID: 30834100.
      Citations:    
    37. De Silva Thompson D, Peticone C, Burova I, Shipley RJ, Knowles JC, Kim HW, Micheletti M, Wall IB. Assessing behaviour of osteoblastic cells in dynamic culture conditions using titanium-doped phosphate glass microcarriers. J Tissue Eng. 2019 Jan-Dec; 10:2041731419825772. PMID: 30800261.
      Citations:    
    38. Muangsanit P, Shipley RJ, Phillips JB. Vascularization Strategies for Peripheral Nerve Tissue Engineering. Anat Rec (Hoboken). 2018 10; 301(10):1657-1667. PMID: 30334363.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    39. Rayner MLD, Laranjeira S, Evans RE, Shipley RJ, Healy J, Phillips JB. Developing an In Vitro Model to Screen Drugs for Nerve Regeneration. Anat Rec (Hoboken). 2018 10; 301(10):1628-1637. PMID: 30334365.
      Citations: 8     Fields:    Translation:AnimalsCells
    40. d'Esposito A, Sweeney PW, Ali M, Saleh M, Ramasawmy R, Roberts TA, Agliardi G, Desjardins A, Lythgoe MF, Pedley RB, Shipley R, Walker-Samuel S. Computational fluid dynamics with imaging of cleared tissue and of in vivo perfusion predicts drug uptake and treatment responses in tumours. Nat Biomed Eng. 2018 10; 2(10):773-787. PMID: 31015649.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    41. Sweeney PW, Walker-Samuel S, Shipley RJ. Insights into cerebral haemodynamics and oxygenation utilising in vivo mural cell imaging and mathematical modelling. Sci Rep. 2018 01 22; 8(1):1373. PMID: 29358701.
      Citations: 14     Fields:    Translation:AnimalsCells
    42. Coy RH, Evans OR, Phillips JB, Shipley RJ. An integrated theoretical-experimental approach to accelerate translational tissue engineering. J Tissue Eng Regen Med. 2018 01; 12(1):e53-e59. PMID: 27792286.
      Citations: 9     Fields:    
    43. Vavourakis V, Wijeratne PA, Shipley R, Loizidou M, Stylianopoulos T, Hawkes DJ. A Validated Multiscale In-Silico Model for Mechano-sensitive Tumour Angiogenesis and Growth. PLoS Comput Biol. 2017 01; 13(1):e1005259. PMID: 28125582.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    44. Chapman LAC, Whiteley JP, Byrne HM, Waters SL, Shipley RJ. Mathematical modelling of cell layer growth in a hollow fibre bioreactor. J Theor Biol. 2017 04 07; 418:36-56. PMID: 28089874.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    45. Kwon KA, Shipley RJ, Edirisinghe M, Best SM, Cameron RE, Poitelea C, Rose GE, Ezra DG. The Mechanics of Brow-Suspension Ptosis Repair: A Comparative Study of Fox Pentagon and Crawford Triangle Techniques. Ophthalmic Plast Reconstr Surg. 2017 Jan/Feb; 33(1):22-26. PMID: 26808175.
      Citations:    Fields:    Translation:Humans
    46. Storm MP, Sorrell I, Shipley R, Regan S, Luetchford KA, Sathish J, Webb S, Ellis MJ. Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture. J Vis Exp. 2016 05 26; (111). PMID: 27285826.
      Citations: 7     Fields:    Translation:HumansCells
    47. Pearson NC, Oliver JM, Shipley RJ, Waters SL. A multiphase model for chemically- and mechanically- induced cell differentiation in a hollow fibre membrane bioreactor: minimising growth factor consumption. Biomech Model Mechanobiol. 2016 06; 15(3):683-700. PMID: 26276678.
      Citations: 2     Fields:    Translation:HumansAnimals
    48. Smith AF, Secomb TW, Pries AR, Smith NP, Shipley RJ. Structure-based algorithms for microvessel classification. Microcirculation. 2015 Feb; 22(2):99-108. PMID: 25403335.
      Citations: 9     Fields:    Translation:Humans
    49. Kwon KA, Shipley RJ, Edirisinghe M, Rayment AW, Best SM, Cameron RE, Salam T, Rose GE, Ezra DG. Stress-relaxation and fatigue behaviour of synthetic brow-suspension materials. J Mech Behav Biomed Mater. 2015 Feb; 42:116-28. PMID: 25481667.
      Citations:    Fields:    
    50. Pearson NC, Waters SL, Oliver JM, Shipley RJ. Multiphase modelling of the effect of fluid shear stress on cell yield and distribution in a hollow fibre membrane bioreactor. Biomech Model Mechanobiol. 2015 Apr; 14(2):387-402. PMID: 25212097.
      Citations: 3     Fields:    Translation:Cells
    51. Ardakani AG, Cheema U, Brown RA, Shipley RJ. Quantifying the correlation between spatially defined oxygen gradients and cell fate in an engineered three-dimensional culture model. J R Soc Interface. 2014 Sep 06; 11(98):20140501. PMID: 24966240.
      Citations: 11     Fields:    Translation:HumansCells
    52. Chapman LA, Shipley RJ, Whiteley JP, Ellis MJ, Byrne HM, Waters SL. Optimising cell aggregate expansion in a perfused hollow fibre bioreactor via mathematical modelling. PLoS One. 2014; 9(8):e105813. PMID: 25157635.
      Citations: 8     Fields:    Translation:AnimalsCells
    53. Smith AF, Shipley RJ, Lee J, Sands GB, LeGrice IJ, Smith NP. Transmural variation and anisotropy of microvascular flow conductivity in the rat myocardium. Ann Biomed Eng. 2014 Sep; 42(9):1966-77. PMID: 24866569.
      Citations: 10     Fields:    Translation:Animals
    54. Kelly CJ, Hussien K, Fokas E, Kannan P, Shipley RJ, Ashton TM, Stratford M, Pearson N, Muschel RJ. Regulation of O2 consumption by the PI3K and mTOR pathways contributes to tumor hypoxia. Radiother Oncol. 2014 Apr; 111(1):72-80. PMID: 24631147.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    55. Kwon KA, Shipley RJ, Edirisinghe M, Ezra DG, Rose GE, Rayment AW, Best SM, Cameron RE. Microstructure and mechanical properties of synthetic brow-suspension materials. Mater Sci Eng C Mater Biol Appl. 2014 Feb 01; 35:220-30. PMID: 24411372.
      Citations: 5     Fields:    Translation:Humans
    56. Pearson NC, Shipley RJ, Waters SL, Oliver JM. Multiphase modelling of the influence of fluid flow and chemical concentration on tissue growth in a hollow fibre membrane bioreactor. Math Med Biol. 2014 Dec; 31(4):393-430. PMID: 24036069.
      Citations: 6     Fields:    Translation:HumansCells
    57. Sorrell I, Shipley RJ, Hearnden V, Colley HE, Thornhill MH, Murdoch C, Webb SD. Combined mathematical modelling and experimentation to predict polymersome uptake by oral cancer cells. Nanomedicine. 2014 Feb; 10(2):339-48. PMID: 24036098.
      Citations: 7     Fields:    Translation:HumansCells
    58. Kwon KA, Shipley RJ, Edirisinghe M, Ezra DG, Rose G, Best SM, Cameron RE. High-speed camera characterization of voluntary eye blinking kinematics. J R Soc Interface. 2013 Aug 06; 10(85):20130227. PMID: 23760297.
      Citations: 31     Fields:    Translation:HumansCTClinical Trials
    59. Williams DP, Shipley R, Ellis MJ, Webb S, Ward J, Gardner I, Creton S. Novel in vitro and mathematical models for the prediction of chemical toxicity. Toxicol Res (Camb). 2013 Jan 01; 2(1):40-59. PMID: 26966512.
      Citations:    
    60. Shipley RJ, Waters SL. Fluid and mass transport modelling to drive the design of cell-packed hollow fibre bioreactors for tissue engineering applications. Math Med Biol. 2012 Dec; 29(4):329-59. PMID: 22076984.
      Citations: 7     Fields:    Translation:HumansCells
    61. Waters SL, Alastruey J, Beard DA, Bovendeerd PH, Davies PF, Jayaraman G, Jensen OE, Lee J, Parker KH, Popel AS, Secomb TW, Siebes M, Sherwin SJ, Shipley RJ, Smith NP, van de Vosse FN. Theoretical models for coronary vascular biomechanics: progress & challenges. Prog Biophys Mol Biol. 2011 Jan; 104(1-3):49-76. PMID: 21040741.
      Citations: 24     Fields:    Translation:Humans
    62. Shipley RJ, Chapman SJ. Multiscale modelling of fluid and drug transport in vascular tumours. Bull Math Biol. 2010 Aug; 72(6):1464-91. PMID: 20099043.
      Citations: 35     Fields:    Translation:Humans
    63. Soleimani M, Shipley RJ, Smith N, Mitchell CN. Medical imaging and physiological modelling: linking physics and biology. Biomed Eng Online. 2009 Jan 12; 8:1. PMID: 19138401.
      Citations: 6     Fields:    
    64. Shipley RJ, Bonsall MB, Allwright DJ, Graham CF. Theoretical exploration of blastocyst morphogenesis. Int J Dev Biol. 2009; 53(4):447-57. PMID: 19247971.
      Citations: 2     Fields:    Translation:Animals
    65. Chapman SJ, Shipley RJ, Jawad R. Multiscale modeling of fluid transport in tumors. Bull Math Biol. 2008 Nov; 70(8):2334-57. PMID: 18818972.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
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