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Adrian H Zai MD, PhD, MPH

TitleAssociate Professor
InstitutionUMass Chan Medical School
DepartmentPopulation and Quantitative Health Sciences
AddressUMass Chan Medical School
368 Plantation Street
Worcester MA 01605
Phone508-856-8994
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentPopulation and Quantitative Health Sciences
    DivisionHealth Informatics And Implementation Science

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentMasters in Clinical Investigation

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentPopulation Health Sciences


    Collapse Biography 
    Collapse education and training
    Boston University, Boston, MA, United StatesBAChemistry
    Harvard University School of Public Health, Boston, MA, United StatesMPHHealthcare Management
    Boston University School of Medicine, Boston, MA, United StatesMD
    Boston University School of Medicine, Boston, MA, United StatesPHDPathology

    Collapse Overview 
    Collapse overview

    Dr. Zai is the Chief Research Informatics Officer at UMass Chan Medical School and an Associate Professor in the Health Informatics and Implementation Science Division. As a researcher and thought leader in his field, Dr. Zai has made significant contributions to healthcare informatics and population health management.

    In his capacity as CRIO, Dr. Zai directs the Research Informatics Core, which caters to all clinical data and data science needs for research at UMass Chan. He is also responsible for overseeing the institution's strategic direction of research informatics infrastructure.

    Dr. Zai's academic research focuses on developing and implementing population-based informatics initiatives. His work employs decision support systems, artificial intelligence, and implementation science to optimize the management of patient populations. Through his innovative research, Dr. Zai aims to enhance patient care and outcomes by harnessing the power of technology and data-driven solutions.



    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zai AH, Wong S, Guilarte-Walker Y, Langlois P, Coleman B, Soni A, McManus DD, Luzuriaga K. Implementing virtual desktops for clinical research at an academic health center: a case report. JAMIA Open. 2024 Oct; 7(3):ooae083. PMID: 39206281.
      Citations:    
    2. Shi Q, Cheah JT, Zai AH. Factors associated with non-adherence to dual-energy x-ray absorptiometry screening during the COVID-19 pandemic in an academic medical center. Arch Osteoporos. 2024 Jul 30; 19(1):66. PMID: 39080113.
      Citations:    
    3. Herbert C, Shi Q, Baek J, Wang B, Kheterpal V, Nowak C, Suvarna T, Singh A, Hartin P, Durnam B, Schrader S, Harman E, Gerber B, Barton B, Zai A, Cohen-Wolkowiez M, Corbie-Smith G, Kibbe W, Marquez J, Hafer N, Broach J, Lin H, Heetderks W, McManus DD, Soni A. Association of neighborhood-level sociodemographic factors with Direct-to-Consumer (DTC) distribution of COVID-19 rapid antigen tests in 5 US communities. BMC Public Health. 2023 09 22; 23(1):1848. PMID: 37735647.
      Citations:    Fields:    Translation:Humans
    4. Soni A, Herbert C, Lin H, Yan Y, Pretz C, Stamegna P, Wang B, Orwig T, Wright C, Tarrant S, Behar S, Suvarna T, Schrader S, Harman E, Nowak C, Kheterpal V, Rao LV, Cashman L, Orvek E, Ayturk D, Gibson L, Zai A, Wong S, Lazar P, Wang Z, Filippaios A, Barton B, Achenbach CJ, Murphy RL, Robinson ML, Manabe YC, Pandey S, Colubri A, O'Connor L, Lemon SC, Fahey N, Luzuriaga KL, Hafer N, Roth K, Lowe T, Stenzel T, Heetderks W, Broach J, McManus DD. Performance of Rapid Antigen Tests to Detect Symptomatic and Asymptomatic SARS-CoV-2 Infection : A Prospective Cohort Study. Ann Intern Med. 2023 07; 176(7):975-982. PMID: 37399548.
      Citations: 7     Fields:    Translation:HumansCells
    5. Soni A, Herbert C, Pretz C, Stamegna P, Filippaios A, Shi Q, Suvarna T, Harman E, Schrader S, Nowak C, Schramm E, Kheterpal V, Behar S, Tarrant S, Ferranto J, Hafer N, Robinson M, Achenbach C, Murphy RL, Manabe YC, Gibson L, Barton B, O'Connor L, Fahey N, Orvek E, Lazar P, Ayturk D, Wong S, Zai A, Cashman L, Rao LV, Luzuriaga K, Lemon S, Blodgett A, Trippe E, Barcus M, Goldberg B, Roth K, Stenzel T, Heetderks W, Broach J, McManus D. Design and implementation of a digital site-less clinical study of serial rapid antigen testing to identify asymptomatic SARS-CoV-2 infection. J Clin Transl Sci. 2023; 7(1):e120. PMID: 37313378.
      Citations:    
    6. Herbert C, Wang B, Lin H, Hafer N, Pretz C, Stamegna P, Tarrant S, Hartin P, Ferranto J, Behar S, Wright C, Orwig T, Suvarna T, Harman E, Schrader S, Nowak C, Kheterpal V, Orvek E, Wong S, Zai A, Barton B, Gerber B, Lemon SC, Filippaios A, D'Amore K, Gibson L, Greene S, Howard-Wilson S, Colubri A, Achenbach C, Murphy R, Heetderks W, Manabe YC, O'Connor L, Fahey N, Luzuriaga K, Broach J, McManus DD, Soni A. Performance of Rapid Antigen Tests Based on Symptom Onset and Close Contact Exposure: A secondary analysis from the Test Us At Home prospective cohort study. medRxiv. 2023 Feb 24. PMID: 36865199.
      Citations:    
    7. Soni A, Herbert C, Lin H, Yan Y, Pretz C, Stamegna P, Wang B, Orwig T, Wright C, Tarrant S, Behar S, Suvarna T, Schrader S, Harman E, Nowak C, Kheterpal V, Rao LV, Cashman L, Orvek E, Ayturk D, Gibson L, Zai A, Wong S, Lazar P, Wang Z, Filippaios A, Barton B, Achenbach CJ, Murphy RL, Robinson M, Manabe YC, Pandey S, Colubri A, O? Connor L, Lemon SC, Fahey N, Luzuriaga KL, Hafer N, Roth K, Lowe T, Stenzel T, Heetderks W, Broach J, McManus DD. Performance of Rapid Antigen Tests to Detect Symptomatic and Asymptomatic SARS-CoV-2 Infection. medRxiv. 2023 Jan 23. PMID: 35982680.
      Citations:    
    8. Soni A, Herbert C, Pretz C, Stamegna P, Filippaios A, Shi Q, Suvarna T, Harman E, Schrader S, Nowak C, Schramm E, Kheterpal V, Behar S, Tarrant S, Ferranto J, Hafer N, Robinson M, Achenbach C, Murphy RL, Manabe YC, Gibson L, Barton B, O'Connor L, Fahey N, Orvek E, Lazar P, Ayturk D, Wong S, Zai A, Cashman L, Rao LV, Luzuriaga K, Lemon S, Blodgett A, Trippe E, Barcus M, Goldberg B, Roth K, Stenzel T, Heetderks W, Broach J, McManus D. Finding a Needle in a Haystack: Design and Implementation of a Digital Site-less Clinical Study of Serial Rapid Antigen Testing to Identify Asymptomatic SARS-CoV-2 Infection. medRxiv. 2023 Jan 23. PMID: 35982663.
      Citations:    
    9. Shi Q, Herbert C, Ward DV, Simin K, McCormick BA, Ellison Iii RT, Zai AH. COVID-19 Variant Surveillance and Social Determinants in Central Massachusetts: Development Study. JMIR Form Res. 2022 Jun 13; 6(6):e37858. PMID: 35658093.
      Citations:    
    10. Soni A, Herbert C, Baek J, Shi Q, Marquez J, Harman E, Kheterpal V, Nowak C, Suvarna T, Lin H, Heetderks W, Zai A, Cohen-Wolkowiez M, Corbie-Smith G, Kibbe W, Gerber BS, Hafer N, Barton B, Broach J, McManus D. Association of Mass Distribution of Rapid Antigen Tests and SARS-CoV-2 Prevalence: Results from NIH-CDC funded Say Yes! Covid Test program in Michigan. medRxiv. 2022 Apr 02. PMID: 35411342.
      Citations:    
    11. Pfaff ER, Girvin AT, Gabriel DL, Kostka K, Morris M, Palchuk MB, Lehmann HP, Amor B, Bissell M, Bradwell KR, Gold S, Hong SS, Loomba J, Manna A, McMurry JA, Niehaus E, Qureshi N, Walden A, Zhang XT, Zhu RL, Moffitt RA, Haendel MA, Chute CG, Adams WG, Al-Shukri S, Anzalone A, Baghal A, Bennett TD, Bernstam EV, Bernstam EV, Bissell MM, Bush B, Campion TR, Castro V, Chang J, Chaudhari DD, Chen W, Chu S, Cimino JJ, Crandall KA, Crooks M, Davies SJD, DiPalazzo J, Dorr D, Eckrich D, Eltinge SE, Fort DG, Golovko G, Gupta S, Haendel MA, Hajagos JG, Hanauer DA, Harnett BM, Horswell R, Huang N, Johnson SG, Kahn M, Khanipov K, Kieler C, Luzuriaga KR, Maidlow S, Martinez A, Mathew J, McClay JC, McMahan G, Melancon B, Meystre S, Miele L, Morizono H, Pablo R, Patel L, Phuong J, Popham DJ, Pulgarin C, Santos C, Sarkar IN, Sazo N, Setoguchi S, Soby S, Surampalli S, Suver C, Vangala UMR, Visweswaran S, Oehsen JV, Walters KM, Wiley L, Williams DA, Zai A. Synergies between centralized and federated approaches to data quality: a report from the national COVID cohort collaborative. J Am Med Inform Assoc. 2022 03 15; 29(4):609-618. PMID: 34590684.
      Citations: 24     Fields:    Translation:Humans
    12. Zai AH, Caffrey M, O'Brien CS, Jiang D, Kanyat R, Silacci S. The Implementation and Acceptability of a Combined Mobile Application with a COVID-19 at-Home Test Kit. Telemed J E Health. 2022 07; 28(7):1064-1069. PMID: 34898259.
      Citations:    Fields:    Translation:HumansPHPublic Health
    13. Simione M, Farrar-Muir H, Mini FN, Perkins ME, Luo M, Frost H, Orav EJ, Metlay J, Zai AH, Kistin CJ, Sease K, Hambidge SJ, Taveras EM. Implementation of the Connect for Health pediatric weight management program: study protocol and baseline characteristics. J Comp Eff Res. 2021 08; 10(11):881-892. PMID: 34024120.
      Citations: 3     Fields:    Translation:Humans
    14. Ashburner JM, Lee PR, Rivet CM, Barr Vermilya H, Lubitz SA, Zai AH. The Implementation and Acceptability of a Mobile Application for Screening for Atrial Fibrillation at Home. Telemed J E Health. 2021 11; 27(11):1305-1310. PMID: 33606553.
      Citations: 2     Fields:    Translation:Humans
    15. Adans-Dester CP, Bamberg S, Bertacchi FP, Caulfield B, Chappie K, Demarchi D, Erb MK, Estrada J, Fabara EE, Freni M, Friedl KE, Ghaffari R, Gill G, Greenberg MS, Hoyt RW, Jovanov E, Kanzler CM, Katabi D, Kernan M, Kigin C, Lee SI, Leonhardt S, Lovell NH, Mantilla J, McCoy TH, Luo NM, Miller GA, Moore J, O'Keeffe D, Palmer J, Parisi F, Patel S, Po J, Pugliese BL, Quatieri T, Rahman T, Ramasarma N, Rogers JA, Ruiz-Esparza GU, Sapienza S, Schiurring G, Schwamm L, Shafiee H, Kelly Silacci S, Sims NM, Talkar T, Tharion WJ, Toombs JA, Uschnig C, Vergara-Diaz GP, Wacnik P, Wang MD, Welch J, Williamson L, Zafonte R, Zai A, Zhang YT, Tearney GJ, Ahmad R, Walt DR, Bonato P. Can mHealth Technology Help Mitigate the Effects of the COVID-19 Pandemic? IEEE Open J Eng Med Biol. 2020; 1:243-248. PMID: 34192282.
      Citations:    
    16. Ashburner JM, Horn DM, O'Keefe SM, Zai AH, Chang Y, Wagle NW, Atlas SJ. Chronic disease outcomes from primary care population health program implementation. Am J Manag Care. 2017 Dec; 23(12):728-735. PMID: 29261239.
      Citations: 5     Fields:    Translation:Humans
    17. Bobb JF, Ho KK, Yeh RW, Harrington L, Zai A, Liao KP, Dominici F. Time-Course of Cause-Specific Hospital Admissions During Snowstorms: An Analysis of Electronic Medical Records From Major Hospitals in Boston, Massachusetts. Am J Epidemiol. 2017 02 15; 185(4):283-294. PMID: 28137774.
      Citations: 9     Fields:    Translation:Humans
    18. Hwang AS, Atlas SJ, Hong J, Ashburner JM, Zai AH, Grant RW, Hong CS. Defining Team Effort Involved in Patient Care from the Primary Care Physician's Perspective. J Gen Intern Med. 2017 Mar; 32(3):269-276. PMID: 27770385.
      Citations: 7     Fields:    Translation:Humans
    19. Rotenstein L, Tucker S, Kakoza R, Tishler L, Zai A, Wu C. The critical components of an electronic care plan tool for primary care: an exploratory qualitative study. J Innov Health Inform. 2016 07 04; 23(2):836. PMID: 27869585.
      Citations: 1     Fields:    Translation:Humans
    20. Percac-Lima S, Ashburner JM, Zai AH, Chang Y, Oo SA, Guimaraes E, Atlas SJ. Patient Navigation for Comprehensive Cancer Screening in High-Risk Patients Using a Population-Based Health Information Technology System: A Randomized Clinical Trial. JAMA Intern Med. 2016 Jul 01; 176(7):930-7. PMID: 27273602.
      Citations: 38     Fields:    Translation:Humans
    21. Eisenstat SA, Chang Y, Porneala BC, Geagan E, Wilkins G, Chase B, O'Keefe SM, Delahanty LM, Atlas SJ, Zai AH, Finn D, Weil E, Wexler DJ. Development and Implementation of a Collaborative Team Care Model for Effective Insulin Use in an Academic Medical Center Primary Care Network. Am J Med Qual. 2017 Jul/Aug; 32(4):397-405. PMID: 27259871.
      Citations: 3     Fields:    Translation:Humans
    22. Percac-Lima S, Singer DE, Cronin PR, Chang Y, Zai AH. Can Text Messages Improve Attendance to Primary Care Appointments in Underserved Populations? J Health Care Poor Underserved. 2016; 27(4):1709-1725. PMID: 27818433.
      Citations: 5     Fields:    Translation:Humans
    23. Levy DE, Munshi VN, Ashburner JM, Zai AH, Grant RW, Atlas SJ. Health IT-assisted population-based preventive cancer screening: a cost analysis. Am J Manag Care. 2015 Dec; 21(12):885-91. PMID: 26671700.
      Citations: 1     Fields:    Translation:Humans
    24. Wu CA, Mulder AL, Zai AH, Hu Y, Costa M, Tishler LW, Saltzman JR, Ellner AL, Bitton A. A population management system for improving colorectal cancer screening in a primary care setting. J Eval Clin Pract. 2016 Jun; 22(3):319-28. PMID: 26259696.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    25. Berkowitz SA, Percac-Lima S, Ashburner JM, Chang Y, Zai AH, He W, Grant RW, Atlas SJ. Building Equity Improvement into Quality Improvement: Reducing Socioeconomic Disparities in Colorectal Cancer Screening as Part of Population Health Management. J Gen Intern Med. 2015 Jul; 30(7):942-9. PMID: 25678378.
      Citations: 17     Fields:    Translation:Humans
    26. Cronin PR, Greenwald JL, Crevensten GC, Chueh HC, Zai AH. Development and implementation of a real-time 30-day readmission predictive model. AMIA Annu Symp Proc. 2014; 2014:424-31. PMID: 25954346.
      Citations: 9     Fields:    Translation:Humans
    27. Wasfy JH, Strom JB, Waldo SW, O'Brien C, Wimmer NJ, Zai AH, Luttrell J, Spertus JA, Kennedy KF, Normand SL, Mauri L, Yeh RW. Clinical preventability of 30-day readmission after percutaneous coronary intervention. J Am Heart Assoc. 2014 Sep 26; 3(5):e001290. PMID: 25261531.
      Citations: 11     Fields:    Translation:HumansPHPublic Health
    28. Atlas SJ, Zai AH, Ashburner JM, Chang Y, Percac-Lima S, Levy DE, Chueh HC, Grant RW. Non-visit-based cancer screening using a novel population management system. J Am Board Fam Med. 2014 Jul-Aug; 27(4):474-85. PMID: 25002002.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    29. Wasfy JH, Strom JB, O'Brien C, Zai AH, Luttrell J, Kennedy KF, Spertus JA, Zelevinsky K, Normand SL, Mauri L, Yeh RW. Causes of short-term readmission after percutaneous coronary intervention. Circ Cardiovasc Interv. 2014 Feb; 7(1):97-103. PMID: 24425587.
      Citations: 15     Fields:    Translation:Humans
    30. Zai AH, Kim S, Kamis A, Hung K, Ronquillo JG, Chueh HC, Atlas SJ. Applying operations research to optimize a novel population management system for cancer screening. J Am Med Inform Assoc. 2014 Feb; 21(e1):e129-35. PMID: 24043318.
      Citations: 9     Fields:    Translation:Humans
    31. Zai AH, Ronquillo JG, Nieves R, Chueh HC, Kvedar JC, Jethwani K. Assessing hospital readmission risk factors in heart failure patients enrolled in a telemonitoring program. Int J Telemed Appl. 2013; 2013:305819. PMID: 23710170.
      Citations:    
    32. Beauharnais CC, Larkin ME, Zai AH, Boykin EC, Luttrell J, Wexler DJ. Efficacy and cost-effectiveness of an automated screening algorithm in an inpatient clinical trial. Clin Trials. 2012 Apr; 9(2):198-203. PMID: 22308560.
      Citations: 22     Fields:    Translation:Humans
    33. Watson AJ, O'Rourke J, Jethwani K, Cami A, Stern TA, Kvedar JC, Chueh HC, Zai AH. Linking electronic health record-extracted psychosocial data in real-time to risk of readmission for heart failure. Psychosomatics. 2011 Jul-Aug; 52(4):319-27. PMID: 21777714.
      Citations: 21     Fields:    Translation:Humans
    34. Zai AH, Farr KM, Grant RW, Mort E, Ferris TG, Chueh HC. Queuing theory to guide the implementation of a heart failure inpatient registry program. J Am Med Inform Assoc. 2009 Jul-Aug; 16(4):516-23. PMID: 19390108.
      Citations: 4     Fields:    Translation:Humans
    35. Zai AH, Grant RW, Estey G, Lester WT, Andrews CT, Yee R, Mort E, Chueh HC. Lessons from implementing a combined workflow-informatics system for diabetes management. J Am Med Inform Assoc. 2008 Jul-Aug; 15(4):524-33. PMID: 18436907.
      Citations: 12     Fields:    Translation:Humans
    36. Lester WT, Zai AH, Chueh HC, Grant RW. Diabetes information technology: designing informatics systems to catalyze change in clinical care. J Diabetes Sci Technol. 2008 Mar; 2(2):275-83. PMID: 19885355.
      Citations: 2     Fields:    
    37. Lester WT, Zai AH, Grant RW, Chueh HC. Designing healthcare information technology to catalyse change in clinical care. Inform Prim Care. 2008; 16(1):9-19. PMID: 18534073.
      Citations: 6     Fields:    Translation:Humans
    38. Zai A, Grant R, Andrews C, Yee R, Chueh H. Improving diabetes population management efficiency with an informatics solution. AMIA Annu Symp Proc. 2007 Oct 11; 1168. PMID: 18694264.
      Citations:    Fields:    Translation:Humans
    39. Zai A, Chung J, Chueh H. Web-based residency training program reviews influence applicants who use them. AMIA Annu Symp Proc. 2005; 1166. PMID: 16779452.
      Citations:    Fields:    Translation:Humans
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