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KyoungHwan Lee PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
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    InstitutionT.H. Chan School of Medicine

    Collapse Biography 
    Collapse education and training
    Konkuk University, Seoul, , Korea, Republic ofPHDPlant Biology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ma W, Gong H, Jani V, Lee KH, Landim-Vieira M, Papadaki M, Pinto JR, Aslam MI, Cammarato A, Irving T. Myofibril orientation as a metric for characterizing heart disease. Biophys J. 2022 02 15; 121(4):565-574. PMID: 35032456.
      Citations: 11     Fields:    Translation:AnimalsCells
    2. Song T, McNamara JW, Ma W, Landim-Vieira M, Lee KH, Martin LA, Heiny JA, Lorenz JN, Craig R, Pinto JR, Irving T, Sadayappan S. Fast skeletal myosin-binding protein-C regulates fast skeletal muscle contraction. Proc Natl Acad Sci U S A. 2021 04 27; 118(17). PMID: 33888578.
      Citations: 16     Fields:    Translation:AnimalsCells
    3. Lynch TL, Kumar M, McNamara JW, Kuster DWD, Sivaguru M, Singh RR, Previs MJ, Lee KH, Kuffel G, Zilliox MJ, Lin BL, Ma W, Gibson AM, Blaxall BC, Nieman ML, Lorenz JN, Leichter DM, Leary OP, Janssen PML, de Tombe PP, Gilbert RJ, Craig R, Irving T, Warshaw DM, Sadayappan S. Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility. J Mol Cell Cardiol. 2021 07; 156:33-44. PMID: 33781820.
      Citations: 9     Fields:    Translation:AnimalsCells
    4. Yang S, Tiwari P, Lee KH, Sato O, Ikebe M, Padr?n R, Craig R. Cryo-EM structure of the inhibited (10S) form of myosin II. Nature. 2020 12; 588(7838):521-525. PMID: 33268893.
      Citations: 28     Fields:    Translation:AnimalsCells
    5. Padr?n R, Ma W, Duno-Miranda S, Koubassova N, Lee KH, Pinto A, Alamo L, Bola?os P, Tsaturyan A, Irving T, Craig R. The myosin interacting-heads motif present in live tarantula muscle explains tetanic and posttetanic phosphorylation mechanisms. Proc Natl Acad Sci U S A. 2020 06 02; 117(22):11865-11874. PMID: 32444484.
      Citations: 25     Fields:    Translation:AnimalsCells
    6. Kuster DWD, Lynch TL, Barefield DY, Sivaguru M, Kuffel G, Zilliox MJ, Lee KH, Craig R, Namakkal-Soorappan R, Sadayappan S. Altered C10 domain in cardiac myosin binding protein-C results in hypertrophic cardiomyopathy. Cardiovasc Res. 2019 12 01; 115(14):1986-1997. PMID: 31050699.
      Citations: 13     Fields:    Translation:AnimalsCells
    7. Ma W, Lee KH, Yang S, Irving TC, Craig R. Lattice arrangement of myosin filaments correlates with fiber type in rat skeletal muscle. J Gen Physiol. 2019 12 02; 151(12):1404-1412. PMID: 31699797.
      Citations: 9     Fields:    Translation:AnimalsCells
    8. Yang S, Lee KH, Woodhead JL, Sato O, Ikebe M, Craig R. The central role of the tail in switching off 10S myosin II activity. J Gen Physiol. 2019 09 02; 151(9):1081-1093. PMID: 31387899.
      Citations: 10     Fields:    Translation:AnimalsCells
    9. Lee KH, Sulbar?n G, Yang S, Mun JY, Alamo L, Pinto A, Sato O, Ikebe M, Liu X, Korn ED, Sarsoza F, Bernstein SI, Padr?n R, Craig R. Interacting-heads motif has been conserved as a mechanism of myosin II inhibition since before the origin of animals. Proc Natl Acad Sci U S A. 2018 02 27; 115(9):E1991-E2000. PMID: 29444861.
      Citations: 54     Fields:    Translation:AnimalsCells
    10. Kirk JA, Chakir K, Lee KH, Karst E, Holewinski RJ, Pironti G, Tunin RS, Pozios I, Abraham TP, de Tombe P, Rockman HA, Van Eyk JE, Craig R, Farazi TG, Kass DA. Pacemaker-induced transient asynchrony suppresses heart failure progression. Sci Transl Med. 2015 Dec 23; 7(319):319ra207. PMID: 26702095.
      Citations: 19     Fields:    Translation:AnimalsCells
    11. Previs MJ, Prosser BL, Mun JY, Previs SB, Gulick J, Lee K, Robbins J, Craig R, Lederer WJ, Warshaw DM. Myosin-binding protein C corrects an intrinsic inhomogeneity in cardiac excitation-contraction coupling. Sci Adv. 2015; 1(1). PMID: 25839057.
      Citations: 46     Fields:    
    12. Lee K, Harris SP, Sadayappan S, Craig R. Orientation of myosin binding protein C in the cardiac muscle sarcomere determined by domain-specific immuno-EM. J Mol Biol. 2015 Jan 30; 427(2):274-86. PMID: 25451032.
      Citations: 28     Fields:    Translation:AnimalsCells
    13. Lee K, Nah SY, Kim ES. Micromorphology and development of the epicuticular structure on the epidermal cell of ginseng leaves. J Ginseng Res. 2015 Apr; 39(2):135-40. PMID: 26045686.
    14. Craig R, Lee KH, Mun JY, Torre I, Luther PK. Structure, sarcomeric organization, and thin filament binding of cardiac myosin-binding protein-C. Pflugers Arch. 2014 Mar; 466(3):425-31. PMID: 24413886.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    15. Lin B, Govindan S, Lee K, Zhao P, Han R, Runte KE, Craig R, Palmer BM, Sadayappan S. Cardiac myosin binding protein-C plays no regulatory role in skeletal muscle structure and function. PLoS One. 2013; 8(7):e69671. PMID: 23936073.
      Citations: 22     Fields:    Translation:AnimalsCells
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