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Lei Huang PhD

InstitutionUMass Chan Medical School
DepartmentMolecular, Cell and Cancer Biology
AddressUMass Chan Medical School-Lazare Research Building
364 Plantation Street
Worcester MA 01605
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMolecular, Cell and Cancer Biology

    Collapse Biography 
    Collapse education and training
    Tianjin University, Tianjin, , ChinaBSLife Sciences
    South China Normal University, Guangzhou, , ChinaPHDBiophysics

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Huang L, Liu P, Du Y, Pan D, Lee A, Wolfe SA, Wang YX. A brown fat-enriched adipokine, ASRA, is a leptin receptor antagonist that stimulates appetite. bioRxiv. 2023 Sep 12. PMID: 37745491.
    2. Liu P, Huang L, Song CQ. Editorial: Genome editing applications of CRISPR/Cas9 in metabolic diseases, hormonal system and cancer research. Front Endocrinol (Lausanne). 2023; 14:1256966. PMID: 37608792.
      Citations:    Fields:    Translation:Humans
    3. Huang L. Editorial: Signaling crosstalk in obesity and adipose tissue-derived metabolic diseases. Front Physiol. 2023; 14:1233284. PMID: 37378076.
    4. Chen Q, Huang L, Pan D, Hu K, Li R, Friedline RH, Kim JK, Zhu LJ, Guertin DA, Wang YX. A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis. Nat Commun. 2022 Dec 10; 13(1):7633. PMID: 36496438.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    5. Huang L, Zhang XO, Rozen EJ, Sun X, Sallis B, Verdejo-Torres O, Wigglesworth K, Moon D, Huang T, Cavaretta JP, Wang G, Zhang L, Shohet JM, Lee MM, Wu Q. PRMT5 activates AKT via methylation to promote tumor metastasis. Nat Commun. 2022 07 08; 13(1):3955. PMID: 35803962.
      Citations: 14     Fields:    Translation:HumansCells
    6. Huang L, Liu P, Yang Q, Wang YX. The KRAB Domain-Containing Protein ZFP961 Represses Adipose Thermogenesis and Energy Expenditure through Interaction with PPARa. Adv Sci (Weinh). 2022 01; 9(2):e2102949. PMID: 34747141.
      Citations: 5     Fields:    Translation:AnimalsCells
    7. Huang L, Liu J, Zhang XO, Sibley K, Najjar SM, Lee MM, Wu Q. Inhibition of protein arginine methyltransferase 5 enhances hepatic mitochondrial biogenesis. J Biol Chem. 2018 07 13; 293(28):10884-10894. PMID: 29773653.
      Citations: 24     Fields:    Translation:AnimalsCells
    8. Chen Q, Huang L, Pan D, Zhu LJ, Wang YX. Cbx4 Sumoylates Prdm16 to Regulate Adipose Tissue Thermogenesis. Cell Rep. 2018 03 13; 22(11):2860-2872. PMID: 29539416.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    9. Huang L, Pan D, Chen Q, Zhu LJ, Ou J, Wabitsch M, Wang YX. Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation. Nat Commun. 2017 07 12; 8(1):68. PMID: 28701693.
      Citations: 19     Fields:    Translation:HumansAnimals
    10. Pan D, Huang L, Zhu LJ, Zou T, Ou J, Zhou W, Wang YX. Jmjd3-Mediated H3K27me3 Dynamics Orchestrate Brown Fat Development and Regulate White Fat Plasticity. Dev Cell. 2015 Dec 07; 35(5):568-583. PMID: 26625958.
      Citations: 46     Fields:    Translation:AnimalsCells
    11. Zoltan-Jones A, Huang L, Ghatak S, Toole BP. Elevated hyaluronan production induces mesenchymal and transformed properties in epithelial cells. J Biol Chem. 2003 Nov 14; 278(46):45801-10. PMID: 12954618.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    12. Ward JA, Huang L, Guo H, Ghatak S, Toole BP. Perturbation of hyaluronan interactions inhibits malignant properties of glioma cells. Am J Pathol. 2003 May; 162(5):1403-9. PMID: 12707023.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
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