John Pezzuto to Inhibitory Concentration 50
This is a "connection" page, showing publications John Pezzuto has written about Inhibitory Concentration 50.
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1.256
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Andreani A, Leoni A, Locatelli A, Morigi R, Rambaldi M, Cervellati R, Greco E, Kondratyuk TP, Park EJ, Huang K, van Breemen RB, Pezzuto JM. Chemopreventive and antioxidant activity of 6-substituted imidazo[2,1-b]thiazoles. Eur J Med Chem. 2013 Oct; 68:412-21.
Score: 0.106
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Kondratyuk TP, Park EJ, Yu R, Van Breemen RB, Asolkar RN, Murphy BT, Fenical W, Pezzuto JM. Novel marine phenazines as potential cancer chemopreventive and anti-inflammatory agents. Mar Drugs. 2012 Feb; 10(2):451-464.
Score: 0.095
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Park EJ, Kiselev E, Conda-Sheridan M, Cushman M, Pezzuto JM. Induction of apoptosis by 3-amino-6-(3-aminopropyl)-5,6-dihydro-5,11-dioxo-11H-indeno[1,2-c]isoquinoline via modulation of MAPKs (p38 and c-Jun N-terminal kinase) and c-Myc in HL-60 human leukemia cells. J Nat Prod. 2012 Mar 23; 75(3):378-84.
Score: 0.094
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Luqman S, Meena A, Marler LE, Kondratyuk TP, Pezzuto JM. Suppression of tumor necrosis factor-a-induced nuclear factor ?B activation and aromatase activity by capsaicin and its analog capsazepine. J Med Food. 2011 Nov; 14(11):1344-51.
Score: 0.091
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Morais MC, Luqman S, Kondratyuk TP, Petronio MS, Regasini LO, Silva DH, Bolzani VS, Soares CP, Pezzuto JM. Suppression of TNF-a induced NF?B activity by gallic acid and its semi-synthetic esters: possible role in cancer chemoprevention. Nat Prod Res. 2010 Nov; 24(18):1758-65.
Score: 0.087
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Asolkar RN, Freel KC, Jensen PR, Fenical W, Kondratyuk TP, Park EJ, Pezzuto JM. Arenamides A-C, cytotoxic NFkappaB inhibitors from the marine actinomycete Salinispora arenicola. J Nat Prod. 2009 Mar 27; 72(3):396-402.
Score: 0.078
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Tamez PA, Lantvit D, Lim E, Pezzuto JM. Chemosensitizing action of cepharanthine against drug-resistant human malaria, Plasmodium falciparum. J Ethnopharmacol. 2005 Apr 08; 98(1-2):137-42.
Score: 0.059
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Mi Q, Lantvit D, Reyes-Lim E, Chai H, Zhao W, Lee IS, Peraza-S?nchez S, Ngassapa O, Kardono LB, Riswan S, Hollingshead MG, Mayo JG, Farnsworth NR, Cordell GA, Kinghorn AD, Pezzuto JM. Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests. J Nat Prod. 2002 Jun; 65(6):842-50.
Score: 0.049
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Misico RI, Song LL, Veleiro AS, Cirigliano AM, Tettamanzi MC, Burton G, Bonetto GM, Nicotra VE, Silva GL, Gil RR, Oberti JC, Kinghorn AD, Pezzuto JM. Induction of quinone reductase by withanolides. J Nat Prod. 2002 May; 65(5):677-80.
Score: 0.048
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Zhang M, Park EJ, Kondratyuk TP, Pezzuto JM, Sun D. Synthesis and Structure-Activity Relationships of Tetrahydro-?-carboline Derivatives as Anticancer and Cancer-chemopreventive Agents. Anticancer Res. 2018 Aug; 38(8):4425-4433.
Score: 0.037
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Prior AM, Yu X, Park EJ, Kondratyuk TP, Lin Y, Pezzuto JM, Sun D. Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1. Bioorg Med Chem Lett. 2017 12 15; 27(24):5393-5399.
Score: 0.035
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Yu X, Park EJ, Kondratyuk TP, Pezzuto JM, Sun D. Synthesis of 2-arylindole derivatives and evaluation as nitric oxide synthase and NF?B inhibitors. Org Biomol Chem. 2012 Nov 28; 10(44):8835-47.
Score: 0.025
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Shen L, Park EJ, Kondratyuk TP, Guendisch D, Marler L, Pezzuto JM, Wright AD, Sun D. Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents. Bioorg Med Chem. 2011 Nov 01; 19(21):6182-95.
Score: 0.023
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Yang JH, Kondratyuk TP, Jermihov KC, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Huang R, Liu Y, Wang LQ, Mesecar AD, van Breemen RB, Pezzuto JM, Fong HH, Chen YG, Zhang HJ. Bioactive compounds from the fern Lepisorus contortus. J Nat Prod. 2011 Feb 25; 74(2):129-36.
Score: 0.022
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Hoshino J, Park EJ, Kondratyuk TP, Marler L, Pezzuto JM, van Breemen RB, Mo S, Li Y, Cushman M. Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites. J Med Chem. 2010 Jul 08; 53(13):5033-43.
Score: 0.021
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Cheenpracha S, Park EJ, Rostama B, Pezzuto JM, Chang LC. Inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-activated murine macrophage RAW 264.7 cells by the norsesterterpene peroxide, epimuqubilin A. Mar Drugs. 2010 Mar 01; 8(3):429-37.
Score: 0.021
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Yang JH, Kondratyuk TP, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Pegan S, Liu Y, Wang LQ, Mesecar AD, Van Breemen RB, Pezzuto JM, Fong HH, Chen YG, Zhang HJ. Isolation and evaluation of kaempferol glycosides from the fern Neocheiropteris palmatopedata. Phytochemistry. 2010 Apr; 71(5-6):641-7.
Score: 0.021
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Kang SS, Cuendet M, Endringer DC, Croy VL, Pezzuto JM, Lipton MA. Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kappaB. Bioorg Med Chem. 2009 Feb 01; 17(3):1044-54.
Score: 0.018
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Williams PG, Asolkar RN, Kondratyuk T, Pezzuto JM, Jensen PR, Fenical W. Saliniketals A and B, bicyclic polyketides from the marine actinomycete Salinispora arenicola. J Nat Prod. 2007 Jan; 70(1):83-8.
Score: 0.017
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Carcache-Blanco EJ, Cuendet M, Park EJ, Su BN, Rivero-Cruz JF, Farnsworth NR, Pezzuto JM, Douglas Kinghorn A. Potential cancer chemopreventive agents from Arbutus unedo. Nat Prod Res. 2006 Apr; 20(4):327-34.
Score: 0.016
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Homhual S, Bunyapraphatsara N, Kondratyuk T, Herunsalee A, Chaukul W, Pezzuto JM, Fong HH, Zhang HJ. Bioactive dammarane triterpenes from the mangrove plant Bruguiera gymnorrhiza. J Nat Prod. 2006 Mar; 69(3):421-4.
Score: 0.016
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Homhual S, Zhang HJ, Bunyapraphatsara N, Kondratyuk TP, Santarsiero BD, Mesecar AD, Herunsalee A, Chaukul W, Pezzuto JM, Fong HH. Bruguiesulfurol, a new sulfur compound from Bruguiera gymnorrhiza. Planta Med. 2006 Feb; 72(3):255-60.
Score: 0.016
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Zhang HJ, Nguyen VH, Nguyen MC, Soejarto DD, Pezzuto JM, Fong HH, Tan GT. Sesquiterpenes and butenolides, natural anti-HIV constituents from Litsea verticillata. Planta Med. 2005 May; 71(5):452-7.
Score: 0.015
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Jang DS, Cuendet M, Su BN, Totura S, Riswan S, Fong HH, Pezzuto JM, Kinghorn AD. Constituents of the seeds of Hernandia ovigera with inhibitory activity against cyclooxygenase-2. Planta Med. 2004 Oct; 70(10):893-6.
Score: 0.014
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Nguyen QC, Nguyen VH, Santarsiero BD, Mesecar AD, Nguyen MC, Soejarto DD, Pezzuto JM, Fong HH, Tan GT. New 3-O-acyl betulinic acids from Strychnos vanprukii Craib. J Nat Prod. 2004 Jun; 67(6):994-8.
Score: 0.014
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Jang DS, Cuendet M, Pawlus AD, Kardono LB, Kawanishi K, Farnsworth NR, Fong HH, Pezzuto JM, Kinghorn AD. Potential cancer chemopreventive constituents of the leaves of Macaranga triloba. Phytochemistry. 2004 Feb; 65(3):345-50.
Score: 0.014
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Zhang HJ, Sydara K, Tan GT, Ma C, Southavong B, Soejarto DD, Pezzuto JM, Fong HH. Bioactive constituents from Asparagus cochinchinensis. J Nat Prod. 2004 Feb; 67(2):194-200.
Score: 0.014
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Topcu G, Aydogmus Z, Imre S, G?ren AC, Pezzuto JM, Clement JA, Kingston DG. Brominated sesquiterpenes from the red alga Laurencia obtusa. J Nat Prod. 2003 Nov; 66(11):1505-8.
Score: 0.013
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D?az F, Ch?vez D, Lee D, Mi Q, Chai HB, Tan GT, Kardono LB, Riswan S, Fairchild CR, Wild R, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo. J Nat Prod. 2003 Jun; 66(6):865-7.
Score: 0.013
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Fang L, Chai HB, Castillo JJ, Soejarto DD, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of Brachistus stramoniifolius. Phytother Res. 2003 May; 17(5):520-3.
Score: 0.013
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Jang DS, Park EJ, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Santarsiero BD, Mesecar AD, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Potential cancer chemopreventive constituents of the seeds of Dipteryx odorata (tonka bean). J Nat Prod. 2003 May; 66(5):583-7.
Score: 0.013
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Zhang HJ, Tan GT, Santarsiero BD, Mesecar AD, Hung NV, Cuong NM, Doel Soejarto D, Pezzuto JM, Fong HH. New Sesquiterpenes from Litsea verticillata. J Nat Prod. 2003 May; 66(5):609-15.
Score: 0.013
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Gafner S, Bergeron C, Batcha LL, Reich J, Arnason JT, Burdette JE, Pezzuto JM, Angerhofer CK. Inhibition of [3H]-LSD binding to 5-HT7 receptors by flavonoids from Scutellaria lateriflora. J Nat Prod. 2003 Apr; 66(4):535-7.
Score: 0.013
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Zhang HJ, Tan GT, Hoang VD, Hung NV, Cuong NM, Soejarto DD, Pezzuto JM, Fong HH. Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea. J Nat Prod. 2003 Feb; 66(2):263-8.
Score: 0.013
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Seo EK, Lee D, Shin YG, Chai HB, Navarro HA, Kardono LB, Rahman I, Cordell GA, Farnsworth NR, Pezzuto JM, Kinghorn AD, Wani MC, Wall ME. Bioactive prenylated flavonoids from the stem bark of Artocarpus kemando. Arch Pharm Res. 2003 Feb; 26(2):124-7.
Score: 0.013
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Duncan CJ, Cuendet M, Fronczek FR, Pezzuto JM, Mehta RG, Hamann MT, Ross SA. Chemical and biological investigation of the fungus Pulveroboletus ravenelii. J Nat Prod. 2003 Jan; 66(1):103-7.
Score: 0.013
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Jang DS, Cuendet M, Hawthorne ME, Kardono LB, Kawanishi K, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Prenylated flavonoids of the leaves of Macaranga conifera with inhibitory activity against cyclooxygenase-2. Phytochemistry. 2002 Dec; 61(7):867-72.
Score: 0.013
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Zhang HJ, Tamez PA, Aydogmus Z, Tan GT, Saikawa Y, Hashimoto K, Nakata M, Hung NV, Xuan le T, Cuong NM, Soejarto DD, Pezzuto JM, Fong HH. Antimalarial agents from plants. III. Trichothecenes from Ficus fistulosa and Rhaphidophora decursiva. Planta Med. 2002 Dec; 68(12):1088-91.
Score: 0.013
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Gu JQ, Park EJ, Vigo JS, Graham JG, Fong HH, Pezzuto JM, Kinghorn AD. Activity-guided isolation of constituents of Renealmia nicolaioides with the potential to induce the phase II enzyme quinone reductase. J Nat Prod. 2002 Nov; 65(11):1616-20.
Score: 0.013
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Su BN, Park EJ, Mbwambo ZH, Santarsiero BD, Mesecar AD, Fong HH, Pezzuto JM, Kinghorn AD. New chemical constituents of Euphorbia quinquecostata and absolute configuration assignment by a convenient Mosher ester procedure carried out in NMR tubes. J Nat Prod. 2002 Sep; 65(9):1278-82.
Score: 0.012
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Gu JQ, Park EJ, Totura S, Riswan S, Fong HH, Pezzuto JM, Kinghorn AD. Constituents of the twigs of Hernandia ovigera that inhibit the transformation of JB6 murine epidermal cells. J Nat Prod. 2002 Jul; 65(7):1065-8.
Score: 0.012
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Zhang H, Fan Z, Tan GT, Chai HB, Pezzuto JM, Sun H, Fong HH. Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodon pseudo-irrorata. J Nat Prod. 2002 Feb; 65(2):215-7.
Score: 0.012