Header Logo

Connection

Raffi Aroian to Caenorhabditis elegans

This is a "connection" page, showing publications Raffi Aroian has written about Caenorhabditis elegans.
Connection Strength

5.897
  1. Kim Y, Nguyen TT, Durning DJ, Ishidate T, Aydemir O, Mello CC, Hu Y, Kahn TW, Aroian RV. Resistance to Cry14A family Bacillus thuringiensis crystal proteins in Caenornabditis elegans operates via the nhr-31 transcription factor and vacuolar-type ATPase pathway. PLoS Pathog. 2024 Oct; 20(10):e1012611.
    View in: PubMed
    Score: 0.589
  2. Sitaram A, Yin Y, Zamaitis T, Zhang B, Aroian RV. A Caenorhabditis elegans nck-1 and filamentous actin-regulating protein pathway mediates a key cellular defense against bacterial pore-forming proteins. PLoS Pathog. 2022 11; 18(11):e1010656.
    View in: PubMed
    Score: 0.515
  3. Somvanshi VS, Ellis BL, Hu Y, Aroian RV. Nitazoxanide: nematicidal mode of action and drug combination studies. Mol Biochem Parasitol. 2014 Jan; 193(1):1-8.
    View in: PubMed
    Score: 0.279
  4. Los FC, Ha C, Aroian RV. Neuronal Goa and CAPS regulate behavioral and immune responses to bacterial pore-forming toxins. PLoS One. 2013; 8(1):e54528.
    View in: PubMed
    Score: 0.261
  5. Kho MF, Bellier A, Balasubramani V, Hu Y, Hsu W, Nielsen-LeRoux C, McGillivray SM, Nizet V, Aroian RV. The pore-forming protein Cry5B elicits the pathogenicity of Bacillus sp. against Caenorhabditis elegans. PLoS One. 2011; 6(12):e29122.
    View in: PubMed
    Score: 0.242
  6. Kao CY, Los FC, Huffman DL, Wachi S, Kloft N, Husmann M, Karabrahimi V, Schwartz JL, Bellier A, Ha C, Sagong Y, Fan H, Ghosh P, Hsieh M, Hsu CS, Chen L, Aroian RV. Global functional analyses of cellular responses to pore-forming toxins. PLoS Pathog. 2011 Mar; 7(3):e1001314.
    View in: PubMed
    Score: 0.229
  7. Los FC, Kao CY, Smitham J, McDonald KL, Ha C, Peixoto CA, Aroian RV. RAB-5- and RAB-11-dependent vesicle-trafficking pathways are required for plasma membrane repair after attack by bacterial pore-forming toxin. Cell Host Microbe. 2011 Feb 17; 9(2):147-57.
    View in: PubMed
    Score: 0.228
  8. Hu Y, Platzer EG, Bellier A, Aroian RV. Discovery of a highly synergistic anthelmintic combination that shows mutual hypersusceptibility. Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13):5955-60.
    View in: PubMed
    Score: 0.214
  9. Chen CS, Bellier A, Kao CY, Yang YL, Chen HD, Los FC, Aroian RV. WWP-1 is a novel modulator of the DAF-2 insulin-like signaling network involved in pore-forming toxin cellular defenses in Caenorhabditis elegans. PLoS One. 2010 Mar 02; 5(3):e9494.
    View in: PubMed
    Score: 0.214
  10. Bellier A, Chen CS, Kao CY, Cinar HN, Aroian RV. Hypoxia and the hypoxic response pathway protect against pore-forming toxins in C. elegans. PLoS Pathog. 2009 Dec; 5(12):e1000689.
    View in: PubMed
    Score: 0.210
  11. Bischof LJ, Kao CY, Los FC, Gonzalez MR, Shen Z, Briggs SP, van der Goot FG, Aroian RV. Activation of the unfolded protein response is required for defenses against bacterial pore-forming toxin in vivo. PLoS Pathog. 2008 Oct; 4(10):e1000176.
    View in: PubMed
    Score: 0.194
  12. Barrows BD, Griffitts JS, Aroian RV. Resistance is non-futile: resistance to Cry5B in the nematode Caenorhabditis elegans. J Invertebr Pathol. 2007 Jul; 95(3):198-200.
    View in: PubMed
    Score: 0.175
  13. Barrows BD, Haslam SM, Bischof LJ, Morris HR, Dell A, Aroian RV. Resistance to Bacillus thuringiensis toxin in Caenorhabditis elegans from loss of fucose. J Biol Chem. 2007 Feb 02; 282(5):3302-11.
    View in: PubMed
    Score: 0.171
  14. Bischof LJ, Huffman DL, Aroian RV. Assays for toxicity studies in C. elegans with Bt crystal proteins. Methods Mol Biol. 2006; 351:139-54.
    View in: PubMed
    Score: 0.160
  15. Barrows BD, Griffitts JS, Aroian RV. Caenorhabditis elegans carbohydrates in bacterial toxin resistance. Methods Enzymol. 2006; 417:340-58.
    View in: PubMed
    Score: 0.160
  16. Griffitts JS, Haslam SM, Yang T, Garczynski SF, Mulloy B, Morris H, Cremer PS, Dell A, Adang MJ, Aroian RV. Glycolipids as receptors for Bacillus thuringiensis crystal toxin. Science. 2005 Feb 11; 307(5711):922-5.
    View in: PubMed
    Score: 0.151
  17. Hoang D, Flanagan K, Ding Q, Cazeault NR, Li H, D?az-Valerio S, Rus F, Darfour EA, Kass E, Petersson KH, Nielsen MK, Liesegang H, Ostroff GR, Aroian RV. Bacillus thuringiensis Cry14A family proteins as novel anthelmintics against gastrointestinal nematode parasites. PLoS Negl Trop Dis. 2024 Oct; 18(10):e0012611.
    View in: PubMed
    Score: 0.147
  18. Huffman DL, Abrami L, Sasik R, Corbeil J, van der Goot FG, Aroian RV. Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins. Proc Natl Acad Sci U S A. 2004 Jul 27; 101(30):10995-1000.
    View in: PubMed
    Score: 0.145
  19. Huffman DL, Bischof LJ, Griffitts JS, Aroian RV. Pore worms: using Caenorhabditis elegans to study how bacterial toxins interact with their target host. Int J Med Microbiol. 2004 Apr; 293(7-8):599-607.
    View in: PubMed
    Score: 0.142
  20. Rappleye CA, Tagawa A, Le Bot N, Ahringer J, Aroian RV. Involvement of fatty acid pathways and cortical interaction of the pronuclear complex in Caenorhabditis elegans embryonic polarity. BMC Dev Biol. 2003 Oct 03; 3:8.
    View in: PubMed
    Score: 0.137
  21. Rappleye CA, Tagawa A, Lyczak R, Bowerman B, Aroian RV. The anaphase-promoting complex and separin are required for embryonic anterior-posterior axis formation. Dev Cell. 2002 Feb; 2(2):195-206.
    View in: PubMed
    Score: 0.122
  22. Griffitts JS, Whitacre JL, Stevens DE, Aroian RV. Bt toxin resistance from loss of a putative carbohydrate-modifying enzyme. Science. 2001 Aug 03; 293(5531):860-4.
    View in: PubMed
    Score: 0.118
  23. Tagawa A, Rappleye CA, Aroian RV. Pod-2, along with pod-1, defines a new class of genes required for polarity in the early Caenorhabditis elegans embryo. Dev Biol. 2001 May 15; 233(2):412-24.
    View in: PubMed
    Score: 0.116
  24. Marroquin LD, Elyassnia D, Griffitts JS, Feitelson JS, Aroian RV. Bacillus thuringiensis (Bt) toxin susceptibility and isolation of resistance mutants in the nematode Caenorhabditis elegans. Genetics. 2000 Aug; 155(4):1693-9.
    View in: PubMed
    Score: 0.110
  25. Rappleye CA, Paredez AR, Smith CW, McDonald KL, Aroian RV. The coronin-like protein POD-1 is required for anterior-posterior axis formation and cellular architecture in the nematode caenorhabditis elegans. Genes Dev. 1999 Nov 01; 13(21):2838-51.
    View in: PubMed
    Score: 0.104
  26. Elfawal MA, Savinov SN, Aroian RV. Drug Screening for Discovery of Broad-spectrum Agents for Soil-transmitted Nematodes. Sci Rep. 2019 08 26; 9(1):12347.
    View in: PubMed
    Score: 0.103
  27. Aroian RV, Field C, Pruliere G, Kenyon C, Alberts BM. Isolation of actin-associated proteins from Caenorhabditis elegans oocytes and their localization in the early embryo. EMBO J. 1997 Apr 01; 16(7):1541-9.
    View in: PubMed
    Score: 0.087
  28. Chen HD, Kao CY, Liu BY, Huang SW, Kuo CJ, Ruan JW, Lin YH, Huang CR, Chen YH, Wang HD, Aroian RV, Chen CS. HLH-30/TFEB-mediated autophagy functions in a cell-autonomous manner for epithelium intrinsic cellular defense against bacterial pore-forming toxin in C. elegans. Autophagy. 2017 Feb; 13(2):371-385.
    View in: PubMed
    Score: 0.085
  29. Durmaz E, Hu Y, Aroian RV, Klaenhammer TR. Intracellular and Extracellular Expression of Bacillus thuringiensis Crystal Protein Cry5B in Lactococcus lactis for Use as an Anthelminthic. Appl Environ Microbiol. 2016 02 15; 82(4):1286-94.
    View in: PubMed
    Score: 0.080
  30. Aroian RV, Lesa GM, Sternberg PW. Mutations in the Caenorhabditis elegans let-23 EGFR-like gene define elements important for cell-type specificity and function. EMBO J. 1994 Jan 15; 13(2):360-6.
    View in: PubMed
    Score: 0.070
  31. Aroian RV, Levy AD, Koga M, Ohshima Y, Kramer JM, Sternberg PW. Splicing in Caenorhabditis elegans does not require an AG at the 3' splice acceptor site. Mol Cell Biol. 1993 Jan; 13(1):626-37.
    View in: PubMed
    Score: 0.065
  32. Kao CY, Los FC, Aroian RV. Nervous about immunity: neuronal signals control innate immune system. Nat Immunol. 2008 Dec; 9(12):1329-30.
    View in: PubMed
    Score: 0.049
  33. Hsieh HC, Huang IH, Chang SW, Chen PL, Su YC, Wang S, Tsai WJ, Chen PH, Aroian RV, Chen CS. PRMT-7/PRMT7 activates HLH-30/TFEB to guard plasma membrane integrity compromised by bacterial pore-forming toxins. Autophagy. 2024 06; 20(6):1335-1358.
    View in: PubMed
    Score: 0.035
  34. Griffitts JS, Huffman DL, Whitacre JL, Barrows BD, Marroquin LD, M?ller R, Brown JR, Hennet T, Esko JD, Aroian RV. Resistance to a bacterial toxin is mediated by removal of a conserved glycosylation pathway required for toxin-host interactions. J Biol Chem. 2003 Nov 14; 278(46):45594-602.
    View in: PubMed
    Score: 0.034
  35. Shaver AO, Wit J, Dilks CM, Crombie TA, Li H, Aroian RV, Andersen EC. Variation in anthelmintic responses are driven by genetic differences among diverse C. elegans wild strains. PLoS Pathog. 2023 04; 19(4):e1011285.
    View in: PubMed
    Score: 0.033
  36. Wei JZ, Hale K, Carta L, Platzer E, Wong C, Fang SC, Aroian RV. Bacillus thuringiensis crystal proteins that target nematodes. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2760-5.
    View in: PubMed
    Score: 0.033
  37. Ju S, Chen H, Wang S, Lin J, Ma Y, Aroian RV, Peng D, Sun M. C. elegans monitor energy status via the AMPK pathway to trigger innate immune responses against bacterial pathogens. Commun Biol. 2022 06 30; 5(1):643.
    View in: PubMed
    Score: 0.031
  38. Dementiev A, Board J, Sitaram A, Hey T, Kelker MS, Xu X, Hu Y, Vidal-Quist C, Chikwana V, Griffin S, McCaskill D, Wang NX, Hung SC, Chan MK, Lee MM, Hughes J, Wegener A, Aroian RV, Narva KE, Berry C. The pesticidal Cry6Aa toxin from Bacillus thuringiensis is structurally similar to HlyE-family alpha pore-forming toxins. BMC Biol. 2016 08 30; 14:71.
    View in: PubMed
    Score: 0.021
  39. Wu CC, Hu Y, Miller M, Aroian RV, Sailor MJ. Protection and Delivery of Anthelmintic Protein Cry5B to Nematodes Using Mesoporous Silicon Particles. ACS Nano. 2015 Jun 23; 9(6):6158-67.
    View in: PubMed
    Score: 0.019
  40. Franks SE, Ebrahimi C, Hollands A, Okumura CY, Aroian RV, Nizet V, McGillivray SM. Novel role for the yceGH tellurite resistance genes in the pathogenesis of Bacillus anthracis. Infect Immun. 2014 Mar; 82(3):1132-40.
    View in: PubMed
    Score: 0.017
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.