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Connection

Co-Authors

This is a "connection" page, showing publications co-authored by Paul Thompson and Leonard Barasa.
Connection Strength

6.744
  1. Barasa L, DeOrsey L, O'Reilly MD, Cahill SE, Choudhary S, Allabaji A, Vidadala SR, Sarkar SK, Patil SN, Hale J, Humphries F, Thompson PR. The Development of UM-232, a Covalent STING Antagonist. ACS Med Chem Lett. 2026 Jul 09; 17(7):1547-1554.
    View in: PubMed
    Score: 0.991
  2. Barasa L, DeOrsey L, O'Reilly MD, Choudhary S, Cahill SE, Mathur A, Allabaji A, Nellikkalaya S, Paul S, Vidadala SR, Sarkar SK, Rajendran M, Patil SN, Kalonia H, Hale J, Humphries F, Fitzgerald KA, Thompson PR. Development of UM-200: A Novel Alkyne Amide-Based Inhibitor of the cGAS-STING Pathway. J Med Chem. 2026 Apr 09; 69(7):8561-8582.
    View in: PubMed
    Score: 0.975
  3. Barasa L, DeOrsey L, O'Reilly MD, Choudhary S, Cahill SE, Mathur A, Allabaji A, Vidadala SR, Sarkar SK, Patil SN, Kalonia H, Hale J, Humphries F, Fitzgerald KA, Thompson PR. The Development of UM-203, A Reversible Covalent STING Antagonist. ACS Med Chem Lett. 2026 Jan 08; 17(1):183-191.
    View in: PubMed
    Score: 0.955
  4. Barasa L, DeOrsey L, O'Reilly MD, Choudhary S, Cahill SE, Mathur A, Rajoria S, Green RM, Allabaji A, Nellikkalaya S, Paul S, Vidadala SR, Kumar Sarkar S, Patil SN, Hale J, Humphries F, Fitzgerald KA, Thompson PR. Nitrofuran-Based STING Inhibitors. ACS Omega. 2025 Sep 16; 10(36):41693-41706.
    View in: PubMed
    Score: 0.938
  5. Barasa L, Thompson PR. Protein citrullination: inhibition, identification and insertion. Philos Trans R Soc Lond B Biol Sci. 2023 11 20; 378(1890):20220240.
    View in: PubMed
    Score: 0.821
  6. Barasa L, Chaudhuri S, Zhou JY, Jiang Z, Choudhary S, Green RM, Wiggin E, Cameron M, Humphries F, Fitzgerald KA, Thompson PR. Development of LB244, an Irreversible STING Antagonist. J Am Chem Soc. 2023 09 20; 145(37):20273-20288.
    View in: PubMed
    Score: 0.818
  7. Rossetti T, Han L, Barasa L, Tran T, Hwang S, O'Reilly M, Xu Z, Thompson PR. Development of Next-Generation Fluoroacetamidine-Containing Activity-Based Probes for the Selective Labeling of the Protein Arginine Deiminases (PADs). ACS Chem Biol. 2026 Jul 17; 21(7):1749-1764.
    View in: PubMed
    Score: 0.248
  8. Singh A, Barasa L, DeOrsey L, O'Reilly MD, Choudhary S, Cahill SE, Rossetti T, Green RM, Humphries F, Thompson PR. Triazole-based STING inhibitors. Bioorg Med Chem. 2026 Jan 01; 132:118484.
    View in: PubMed
    Score: 0.238
  9. Icso JD, Barasa L, Thompson PR. SARM1, an Enzyme Involved in Axon Degeneration, Catalyzes Multiple Activities through a Ternary Complex Mechanism. Biochemistry. 2023 07 04; 62(13):2065-2078.
    View in: PubMed
    Score: 0.201
  10. Dawood ZS, Jang A, Mei H, Liggett MR, Wang B, Barasa L, Thompson PR, Couchenour DC, Anand A, Chtraklin K, Liu B, Li Y, Alam HB. Peptidyl arginine deiminase 2 (PAD2) inhibition is associated with acute and long-term benefits in a murine model of traumatic brain injury. J Trauma Acute Care Surg. 2026 Jul 02.
    View in: PubMed
    Score: 0.062
  11. Olea-Flores M, Sharma T, Parikh A, Barasa L, Hachmer S, Dilworth FJ, Padilla-Benavides T, Thompson PR, Imbalzano AN. Reciprocal regulation between the protein arginine deiminases and mSWI/SNF chromatin remodelers controls skeletal muscle differentiation and regeneration. bioRxiv. 2026 Jan 21.
    View in: PubMed
    Score: 0.060
  12. Mann SA, Barasa L, Thompson PR, Weerapana E. Development of a Chemoproteomic Platform to Identify Sites of (Homo)citrullination within Complex Proteomes. ACS Chem Biol. 2025 11 21; 20(11):2741-2754.
    View in: PubMed
    Score: 0.059
  13. Yu X, Song Y, Dong T, Ouyang W, Quan C, Shao L, Barasa L, Thompson PR, Zhang M, Ma J, Kurabayashi K, Li Y. Citrullination of NF-?B p65 by PAD2 as a Novel Therapeutic Target for Modulating Macrophage Polarization in Acute Lung Injury. Adv Sci (Weinh). 2025 May; 12(18):e2413253.
    View in: PubMed
    Score: 0.057
  14. Elfawal MA, Goetz E, Kim Y, Chen P, Savinov SN, Barasa L, Thompson PR, Aroian RV. High-Throughput Screening of More Than 30,000 Compounds for Anthelmintics against Gastrointestinal Nematode Parasites. ACS Infect Dis. 2025 01 10; 11(1):104-120.
    View in: PubMed
    Score: 0.056
  15. Elfawal MA, Goetz E, Kim YM, Chen P, Savinov SN, Barasa L, Thompson PR, Aroian RV. High-throughput screening of more than 30,000 compounds for anthelmintics against gastrointestinal nematode parasites. bioRxiv. 2024 Oct 31.
    View in: PubMed
    Score: 0.055
  16. Dong T, Barasa L, Yu X, Ouyang W, Shao L, Quan C, Wang SH, Zhang J, Salmon M, Tsung A, Alam HB, Ma J, Thompson PR, Li Y. AFM41a: A Novel PAD2 Inhibitor for Sepsis Treatment-Efficacy and Mechanism. Int J Biol Sci. 2024; 20(13):5043-5055.
    View in: PubMed
    Score: 0.055
  17. Pasquero S, Gugliesi F, Biolatti M, Dell'Oste V, Albano C, Bajetto G, Griffante G, Trifir? L, Brugo B, Raviola S, Lacarbonara D, Yang Q, Sudeshna S, Barasa L, Haniff H, Thompson PR, Landolfo S, De Andrea M. Citrullination profile analysis reveals peptidylarginine deaminase 3 as an HSV-1 target to dampen the activity of candidate antiviral restriction factors. PLoS Pathog. 2023 12; 19(12):e1011849.
    View in: PubMed
    Score: 0.052
  18. Geary B, Sun B, Tilvawala RR, Barasa L, Tsoyi K, Rosas IO, Thompson PR, Ho IC. Peptidylarginine deiminase 2 citrullinates MZB1 and promotes the secretion of IgM and IgA. Front Immunol. 2023; 14:1290585.
    View in: PubMed
    Score: 0.052
  19. Humphries F, Shmuel-Galia L, Jiang Z, Zhou JY, Barasa L, Mondal S, Wilson R, Sultana N, Shaffer SA, Ng SL, Pesiridis GS, Thompson PR, Fitzgerald KA. Targeting STING oligomerization with small-molecule inhibitors. Proc Natl Acad Sci U S A. 2023 08 15; 120(33):e2305420120.
    View in: PubMed
    Score: 0.051
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.