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Connection

Charles Specht to Chitin

This is a "connection" page, showing publications Charles Specht has written about Chitin.
Connection Strength

1.443
  1. Maybruck BT, Upadhya R, Lam WC, Specht CA, Lodge JK. Fluorescence and Biochemical Assessment of the Chitin and Chitosan Content of Cryptococcus. Methods Mol Biol. 2024; 2775:329-347.
    View in: PubMed
    Score: 0.223
  2. Bulik DA, Olczak M, Lucero HA, Osmond BC, Robbins PW, Specht CA. Chitin synthesis in Saccharomyces cerevisiae in response to supplementation of growth medium with glucosamine and cell wall stress. Eukaryot Cell. 2003 Oct; 2(5):886-900.
    View in: PubMed
    Score: 0.219
  3. Upadhya R, Baker LG, Lam WC, Specht CA, Donlin MJ, Lodge JK. Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis. mBio. 2018 11 20; 9(6).
    View in: PubMed
    Score: 0.157
  4. Wiesner DL, Specht CA, Lee CK, Smith KD, Mukaremera L, Lee ST, Lee CG, Elias JA, Nielsen JN, Boulware DR, Bohjanen PR, Jenkins MK, Levitz SM, Nielsen K. Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection. PLoS Pathog. 2015 Mar; 11(3):e1004701.
    View in: PubMed
    Score: 0.121
  5. Levitz SM, Huang H, Ostroff GR, Specht CA. Exploiting fungal cell wall components in vaccines. Semin Immunopathol. 2015 Mar; 37(2):199-207.
    View in: PubMed
    Score: 0.119
  6. Jasrapuria S, Specht CA, Kramer KJ, Beeman RW, Muthukrishnan S. Gene families of cuticular proteins analogous to peritrophins (CPAPs) in Tribolium castaneum have diverse functions. PLoS One. 2012; 7(11):e49844.
    View in: PubMed
    Score: 0.103
  7. Chaudhari SS, Arakane Y, Specht CA, Moussian B, Boyle DL, Park Y, Kramer KJ, Beeman RW, Muthukrishnan S. Knickkopf protein protects and organizes chitin in the newly synthesized insect exoskeleton. Proc Natl Acad Sci U S A. 2011 Oct 11; 108(41):17028-33.
    View in: PubMed
    Score: 0.095
  8. Bueter CL, Lee CK, Rathinam VAK, Healy GJ, Taron CH, Specht CA, Levitz SM. Chitosan but not chitin activates the inflammasome by a mechanism dependent upon phagocytosis. J Biol Chem. 2011 Oct 14; 286(41):35447-35455.
    View in: PubMed
    Score: 0.095
  9. Lesage G, Shapiro J, Specht CA, Sdicu AM, M?nard P, Hussein S, Tong AH, Boone C, Bussey H. An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae. BMC Genet. 2005 Feb 16; 6:8.
    View in: PubMed
    Score: 0.060
  10. Chaudhari SS, Moussian B, Specht CA, Arakane Y, Kramer KJ, Beeman RW, Muthukrishnan S. Functional specialization among members of Knickkopf family of proteins in insect cuticle organization. PLoS Genet. 2014 Aug; 10(8):e1004537.
    View in: PubMed
    Score: 0.029
  11. Chaudhari SS, Arakane Y, Specht CA, Moussian B, Kramer KJ, Muthukrishnan S, Beeman RW. Retroactive maintains cuticle integrity by promoting the trafficking of Knickkopf into the procuticle of Tribolium castaneum. PLoS Genet. 2013; 9(1):e1003268.
    View in: PubMed
    Score: 0.026
  12. Bueter CL, Specht CA, Levitz SM. Innate sensing of chitin and chitosan. PLoS Pathog. 2013 Jan; 9(1):e1003080.
    View in: PubMed
    Score: 0.026
  13. Heustis RJ, Ng HK, Brand KJ, Rogers MC, Le LT, Specht CA, Fuhrman JA. Pharyngeal polysaccharide deacetylases affect development in the nematode C. elegans and deacetylate chitin in vitro. PLoS One. 2012; 7(7):e40426.
    View in: PubMed
    Score: 0.025
  14. Merzendorfer H, Kim HS, Chaudhari SS, Kumari M, Specht CA, Butcher S, Brown SJ, Manak JR, Beeman RW, Kramer KJ, Muthukrishnan S. Genomic and proteomic studies on the effects of the insect growth regulator diflubenzuron in the model beetle species Tribolium castaneum. Insect Biochem Mol Biol. 2012 Apr; 42(4):264-76.
    View in: PubMed
    Score: 0.024
  15. Baker LG, Specht CA, Lodge JK. Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans. Eukaryot Cell. 2011 Sep; 10(9):1264-8.
    View in: PubMed
    Score: 0.024
  16. Gerik KJ, Bhimireddy SR, Ryerse JS, Specht CA, Lodge JK. PKC1 is essential for protection against both oxidative and nitrosative stresses, cell integrity, and normal manifestation of virulence factors in the pathogenic fungus Cryptococcus neoformans. Eukaryot Cell. 2008 Oct; 7(10):1685-98.
    View in: PubMed
    Score: 0.019
  17. Van Dellen KL, Bulik DA, Specht CA, Robbins PW, Samuelson JC. Heterologous expression of an Entamoeba histolytica chitin synthase in Saccharomyces cerevisiae. Eukaryot Cell. 2006 Jan; 5(1):203-6.
    View in: PubMed
    Score: 0.016
  18. Banks IR, Specht CA, Donlin MJ, Gerik KJ, Levitz SM, Lodge JK. A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans. Eukaryot Cell. 2005 Nov; 4(11):1902-12.
    View in: PubMed
    Score: 0.016
  19. D?nkler A, Walther A, Specht CA, Wendland J. Candida albicans CHT3 encodes the functional homolog of the Cts1 chitinase of Saccharomyces cerevisiae. Fungal Genet Biol. 2005 Nov; 42(11):935-47.
    View in: PubMed
    Score: 0.016
  20. Colussi PA, Specht CA, Taron CH. Characterization of a nucleus-encoded chitinase from the yeast Kluyveromyces lactis. Appl Environ Microbiol. 2005 Jun; 71(6):2862-9.
    View in: PubMed
    Score: 0.015
  21. Sobering AK, Watanabe R, Romeo MJ, Yan BC, Specht CA, Orlean P, Riezman H, Levin DE. Yeast Ras regulates the complex that catalyzes the first step in GPI-anchor biosynthesis at the ER. Cell. 2004 May 28; 117(5):637-48.
    View in: PubMed
    Score: 0.014
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.