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Connection

Victor Ambros to Animals

This is a "connection" page, showing publications Victor Ambros has written about Animals.
Connection Strength

1.781
  1. Ambros VR, Chalfie M, Daul AL, Fire AZ, Hall DH, Horvitz HR, Mello CC, Ruvkun G, Schroeder NE, Sternberg PW, Rougvie AE. From nematode to Nobel: How community-shared resources fueled the rise of Caenorhabditis elegans as a research organism. Proc Natl Acad Sci U S A. 2025 Dec 02; 122(48):e2522808122.
    View in: PubMed
    Score: 0.067
  2. Ambros V. MicroRNA-mediated gene regulation and the resilience of multicellular animals. Postepy Biochem. 2024 05 23; 70(1):62-70.
    View in: PubMed
    Score: 0.060
  3. Duan Y, Li L, Panzade GP, Piton A, Zinovyeva A, Ambros V. Modeling neurodevelopmental disorder-associated human AGO1 mutations in Caenorhabditis elegans Argonaute alg-1. Proc Natl Acad Sci U S A. 2024 Mar 05; 121(10):e2308255121.
    View in: PubMed
    Score: 0.059
  4. Mirza Z, Walhout AJM, Ambros V. A bacterial pathogen induces developmental slowing by high reactive oxygen species and mitochondrial dysfunction in Caenorhabditis elegans. Cell Rep. 2023 10 31; 42(10):113189.
    View in: PubMed
    Score: 0.057
  5. Ilbay O, Nelson C, Ambros V. C.?elegans LIN-28 controls temporal cell fate progression by regulating LIN-46 expression via the 5' UTR of lin-46 mRNA. Cell Rep. 2021 09 07; 36(10):109670.
    View in: PubMed
    Score: 0.050
  6. Nelson C, Ambros V. A cohort of Caenorhabditis species lacking the highly conserved let-7 microRNA. G3 (Bethesda). 2021 04 23; 11(3).
    View in: PubMed
    Score: 0.048
  7. Ambros V. Development: Keeping Time with Transcription. Curr Biol. 2021 02 22; 31(4):R212-R214.
    View in: PubMed
    Score: 0.048
  8. Vasquez-Rifo A, Ricci EP, Ambros V. Pseudomonas aeruginosa cleaves the decoding center of Caenorhabditis elegans ribosomes. PLoS Biol. 2020 12; 18(12):e3000969.
    View in: PubMed
    Score: 0.047
  9. Vasquez-Rifo A, Veksler-Lublinsky I, Cheng Z, Ausubel FM, Ambros V. The Pseudomonas aeruginosa accessory genome elements influence virulence towards Caenorhabditis elegans. Genome Biol. 2019 12 10; 20(1):270.
    View in: PubMed
    Score: 0.044
  10. Ilbay O, Ambros V. Regulation of nuclear-cytoplasmic partitioning by the lin-28-lin-46 pathway reinforces microRNA repression of HBL-1 to confer robust cell-fate progression in C. elegans. Development. 2019 11 06; 146(21).
    View in: PubMed
    Score: 0.044
  11. Ilbay O, Ambros V. Pheromones and Nutritional Signals Regulate the Developmental Reliance on let-7 Family MicroRNAs in C.?elegans. Curr Biol. 2019 06 03; 29(11):1735-1745.e4.
    View in: PubMed
    Score: 0.042
  12. Choi S, Ambros V. The C. elegans heterochronic gene lin-28 coordinates the timing of hypodermal and somatic gonadal programs for hermaphrodite reproductive system morphogenesis. Development. 2019 03 07; 146(5).
    View in: PubMed
    Score: 0.042
  13. Nelson C, Ambros V. Trans-splicing of the C. elegans let-7 primary transcript developmentally regulates let-7 microRNA biogenesis and let-7 family microRNA activity. Development. 2019 03 04; 146(5).
    View in: PubMed
    Score: 0.042
  14. Ambros V, Ruvkun G. Recent Molecular Genetic Explorations of Caenorhabditis elegans MicroRNAs. Genetics. 2018 07; 209(3):651-673.
    View in: PubMed
    Score: 0.040
  15. McJunkin K, Ambros V. A microRNA family exerts maternal control on sex determination in C. elegans. Genes Dev. 2017 02 15; 31(4):422-437.
    View in: PubMed
    Score: 0.036
  16. Ren Z, Veksler-Lublinsky I, Morrissey D, Ambros V. Staufen Negatively Modulates MicroRNA Activity in Caenorhabditis elegans. G3 (Bethesda). 2016 05 03; 6(5):1227-37.
    View in: PubMed
    Score: 0.034
  17. Zinovyeva AY, Veksler-Lublinsky I, Vashisht AA, Wohlschlegel JA, Ambros VR. Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal. Proc Natl Acad Sci U S A. 2015 Sep 22; 112(38):E5271-80.
    View in: PubMed
    Score: 0.033
  18. Burke SL, Hammell M, Ambros V. Robust Distal Tip Cell Pathfinding in the Face of Temperature Stress Is Ensured by Two Conserved microRNAS in Caenorhabditis elegans. Genetics. 2015 Aug; 200(4):1201-18.
    View in: PubMed
    Score: 0.032
  19. Ren Z, Ambros VR. Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress. Proc Natl Acad Sci U S A. 2015 May 05; 112(18):E2366-75.
    View in: PubMed
    Score: 0.032
  20. Harandi OF, Ambros VR. Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2015 Jan 20; 112(3):E287-96.
    View in: PubMed
    Score: 0.031
  21. McJunkin K, Ambros V. The embryonic mir-35 family of microRNAs promotes multiple aspects of fecundity in Caenorhabditis elegans. G3 (Bethesda). 2014 Jul 21; 4(9):1747-54.
    View in: PubMed
    Score: 0.030
  22. Zinovyeva AY, Bouasker S, Simard MJ, Hammell CM, Ambros V. Mutations in conserved residues of the C. elegans microRNA Argonaute ALG-1 identify separable functions in ALG-1 miRISC loading and target repression. PLoS Genet. 2014 Apr; 10(4):e1004286.
    View in: PubMed
    Score: 0.030
  23. Ambros V. Victor Ambros: the broad scope of microRNAs. Interview by Caitlin Sedwick. J Cell Biol. 2013 May 13; 201(4):492-3.
    View in: PubMed
    Score: 0.028
  24. Karp X, Ambros V. Dauer larva quiescence alters the circuitry of microRNA pathways regulating cell fate progression in C. elegans. Development. 2012 Jun; 139(12):2177-86.
    View in: PubMed
    Score: 0.026
  25. Ambros V. MicroRNAs and developmental timing. Curr Opin Genet Dev. 2011 Aug; 21(4):511-7.
    View in: PubMed
    Score: 0.024
  26. Karp X, Hammell M, Ow MC, Ambros V. Effect of life history on microRNA expression during C. elegans development. RNA. 2011 Apr; 17(4):639-51.
    View in: PubMed
    Score: 0.024
  27. Karp X, Ambros V. The developmental timing regulator HBL-1 modulates the dauer formation decision in Caenorhabditis elegans. Genetics. 2011 Jan; 187(1):345-53.
    View in: PubMed
    Score: 0.023
  28. Ambros V. MicroRNAs: genetically sensitized worms reveal new secrets. Curr Biol. 2010 Jul 27; 20(14):R598-600.
    View in: PubMed
    Score: 0.023
  29. Ambros V. In the tradition of science: an interview with Victor Ambros. PLoS Genet. 2010 Mar 05; 6(3):e1000853.
    View in: PubMed
    Score: 0.022
  30. Ambros V. pRB/CKI pathways at the interface of cell cycle and development. Cell Cycle. 2009 Nov 01; 8(21):3433-4.
    View in: PubMed
    Score: 0.022
  31. Hammell CM, Karp X, Ambros V. A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2009 Nov 03; 106(44):18668-73.
    View in: PubMed
    Score: 0.022
  32. Hammell CM, Lubin I, Boag PR, Blackwell TK, Ambros V. nhl-2 Modulates microRNA activity in Caenorhabditis elegans. Cell. 2009 Mar 06; 136(5):926-38.
    View in: PubMed
    Score: 0.021
  33. Ambros V. The evolution of our thinking about microRNAs. Nat Med. 2008 Oct; 14(10):1036-40.
    View in: PubMed
    Score: 0.020
  34. Ow MC, Martinez NJ, Olsen PH, Silverman HS, Barrasa MI, Conradt B, Walhout AJ, Ambros V. The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans. Genes Dev. 2008 Sep 15; 22(18):2520-34.
    View in: PubMed
    Score: 0.020
  35. Hammell M, Long D, Zhang L, Lee A, Carmack CS, Han M, Ding Y, Ambros V. mirWIP: microRNA target prediction based on microRNA-containing ribonucleoprotein-enriched transcripts. Nat Methods. 2008 Sep; 5(9):813-9.
    View in: PubMed
    Score: 0.020
  36. Sokol NS, Xu P, Jan YN, Ambros V. Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis. Genes Dev. 2008 Jun 15; 22(12):1591-6.
    View in: PubMed
    Score: 0.020
  37. Ambros V, Chen X. The regulation of genes and genomes by small RNAs. Development. 2007 May; 134(9):1635-41.
    View in: PubMed
    Score: 0.018
  38. Ambros V. The 2007 George W. Beadle Medal. Robert K. Herman. Genetics. 2007 Feb; 175(2):465-6.
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    Score: 0.018
  39. Lee RC, Hammell CM, Ambros V. Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans. RNA. 2006 Apr; 12(4):589-97.
    View in: PubMed
    Score: 0.017
  40. Hristova M, Birse D, Hong Y, Ambros V. The Caenorhabditis elegans heterochronic regulator LIN-14 is a novel transcription factor that controls the developmental timing of transcription from the insulin/insulin-like growth factor gene ins-33 by direct DNA binding. Mol Cell Biol. 2005 Dec; 25(24):11059-72.
    View in: PubMed
    Score: 0.017
  41. Karp X, Ambros V. Developmental biology. Encountering microRNAs in cell fate signaling. Science. 2005 Nov 25; 310(5752):1288-9.
    View in: PubMed
    Score: 0.017
  42. Sokol NS, Ambros V. Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth. Genes Dev. 2005 Oct 01; 19(19):2343-54.
    View in: PubMed
    Score: 0.016
  43. Abbott AL, Alvarez-Saavedra E, Miska EA, Lau NC, Bartel DP, Horvitz HR, Ambros V. The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Dev Cell. 2005 Sep; 9(3):403-14.
    View in: PubMed
    Score: 0.016
  44. Ambros V. The functions of animal microRNAs. Nature. 2004 Sep 16; 431(7006):350-5.
    View in: PubMed
    Score: 0.015
  45. Sempere LF, Freemantle S, Pitha-Rowe I, Moss E, Dmitrovsky E, Ambros V. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol. 2004; 5(3):R13.
    View in: PubMed
    Score: 0.015
  46. Ambros V, Lee RC. Identification of microRNAs and other tiny noncoding RNAs by cDNA cloning. Methods Mol Biol. 2004; 265:131-58.
    View in: PubMed
    Score: 0.015
  47. Carrington JC, Ambros V. Role of microRNAs in plant and animal development. Science. 2003 Jul 18; 301(5631):336-8.
    View in: PubMed
    Score: 0.014
  48. Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V. Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity. Dev Biol. 2003 Jul 01; 259(1):9-18.
    View in: PubMed
    Score: 0.014
  49. Ambros V. MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. Cell. 2003 Jun 13; 113(6):673-6.
    View in: PubMed
    Score: 0.014
  50. Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D. MicroRNAs and other tiny endogenous RNAs in C. elegans. Curr Biol. 2003 May 13; 13(10):807-18.
    View in: PubMed
    Score: 0.014
  51. Sempere LF, Dubrovsky EB, Dubrovskaya VA, Berger EM, Ambros V. The expression of the let-7 small regulatory RNA is controlled by ecdysone during metamorphosis in Drosophila melanogaster. Dev Biol. 2002 Apr 01; 244(1):170-9.
    View in: PubMed
    Score: 0.013
  52. Ambros V. microRNAs: tiny regulators with great potential. Cell. 2001 Dec 28; 107(7):823-6.
    View in: PubMed
    Score: 0.013
  53. Lee RC, Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science. 2001 Oct 26; 294(5543):862-4.
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    Score: 0.013
  54. Ambros V. Development. Dicing up RNAs. Science. 2001 Aug 03; 293(5531):811-3.
    View in: PubMed
    Score: 0.012
  55. Ambros V. The temporal control of cell cycle and cell fate in Caenorhabditis elegans. Novartis Found Symp. 2001; 237:203-14; discussion 214-20.
    View in: PubMed
    Score: 0.012
  56. Ambros V. Control of developmental timing in Caenorhabditis elegans. Curr Opin Genet Dev. 2000 Aug; 10(4):428-33.
    View in: PubMed
    Score: 0.012
  57. Hong Y, Lee RC, Ambros V. Structure and function analysis of LIN-14, a temporal regulator of postembryonic developmental events in Caenorhabditis elegans. Mol Cell Biol. 2000 Mar; 20(6):2285-95.
    View in: PubMed
    Score: 0.011
  58. Olsen PH, Ambros V. The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation. Dev Biol. 1999 Dec 15; 216(2):671-80.
    View in: PubMed
    Score: 0.011
  59. Feinbaum R, Ambros V. The timing of lin-4 RNA accumulation controls the timing of postembryonic developmental events in Caenorhabditis elegans. Dev Biol. 1999 Jun 01; 210(1):87-95.
    View in: PubMed
    Score: 0.011
  60. Ambros V. Cell cycle-dependent sequencing of cell fate decisions in Caenorhabditis elegans vulva precursor cells. Development. 1999 May; 126(9):1947-56.
    View in: PubMed
    Score: 0.011
  61. Hong Y, Roy R, Ambros V. Developmental regulation of a cyclin-dependent kinase inhibitor controls postembryonic cell cycle progression in Caenorhabditis elegans. Development. 1998 Sep; 125(18):3585-97.
    View in: PubMed
    Score: 0.010
  62. Moss EG, Lee RC, Ambros V. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell. 1997 Mar 07; 88(5):637-46.
    View in: PubMed
    Score: 0.009
  63. Euling S, Ambros V. Reversal of cell fate determination in Caenorhabditis elegans vulval development. Development. 1996 Aug; 122(8):2507-15.
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    Score: 0.009
  64. Euling S, Ambros V. Heterochronic genes control cell cycle progress and developmental competence of C. elegans vulva precursor cells. Cell. 1996 Mar 08; 84(5):667-76.
    View in: PubMed
    Score: 0.008
  65. Liu Z, Kirch S, Ambros V. The Caenorhabditis elegans heterochronic gene pathway controls stage-specific transcription of collagen genes. Development. 1995 Aug; 121(8):2471-8.
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    Score: 0.008
  66. Rougvie AE, Ambros V. The heterochronic gene lin-29 encodes a zinc finger protein that controls a terminal differentiation event in Caenorhabditis elegans. Development. 1995 Aug; 121(8):2491-500.
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    Score: 0.008
  67. Bala S, Csak T, Momen-Heravi F, Lippai D, Kodys K, Catalano D, Satishchandran A, Ambros V, Szabo G. Biodistribution and function of extracellular miRNA-155 in mice. Sci Rep. 2015 May 29; 5:10721.
    View in: PubMed
    Score: 0.008
  68. Nelson C, Ambros V, Baehrecke EH. miR-14 regulates autophagy during developmental cell death by targeting ip3-kinase 2. Mol Cell. 2014 Nov 06; 56(3):376-388.
    View in: PubMed
    Score: 0.008
  69. Ambros V, Moss EG. Heterochronic genes and the temporal control of C. elegans development. Trends Genet. 1994 Apr; 10(4):123-7.
    View in: PubMed
    Score: 0.007
  70. Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993 Dec 03; 75(5):843-54.
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    Score: 0.007
  71. Zou Y, Chiu H, Zinovyeva A, Ambros V, Chuang CF, Chang C. Developmental decline in neuronal regeneration by the progressive change of two intrinsic timers. Science. 2013 Apr 19; 340(6130):372-376.
    View in: PubMed
    Score: 0.007
  72. Boss? GD, R?egger S, Ow MC, Vasquez-Rifo A, Rondeau EL, Ambros VR, Grosshans H, Simard MJ. The decapping scavenger enzyme DCS-1 controls microRNA levels in Caenorhabditis elegans. Mol Cell. 2013 Apr 25; 50(2):281-7.
    View in: PubMed
    Score: 0.007
  73. Mello CC, Kramer JM, Stinchcomb D, Ambros V. Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J. 1991 Dec; 10(12):3959-70.
    View in: PubMed
    Score: 0.006
  74. Papp A, Rougvie AE, Ambros V. Molecular cloning of lin-29, a heterochronic gene required for the differentiation of hypodermal cells and the cessation of molting in C.elegans. Nucleic Acids Res. 1991 Feb 11; 19(3):623-30.
    View in: PubMed
    Score: 0.006
  75. Liu ZC, Ambros V. Heterochronic genes control the stage-specific initiation and expression of the dauer larva developmental program in Caenorhabditis elegans. Genes Dev. 1989 Dec; 3(12B):2039-49.
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    Score: 0.005
  76. Hong X, Hammell M, Ambros V, Cohen SM. Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets. Proc Natl Acad Sci U S A. 2009 Sep 01; 106(35):15085-90.
    View in: PubMed
    Score: 0.005
  77. Zhang L, Hammell M, Kudlow BA, Ambros V, Han M. Systematic analysis of dynamic miRNA-target interactions during C. elegans development. Development. 2009 Sep; 136(18):3043-55.
    View in: PubMed
    Score: 0.005
  78. Ambros V. A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans. Cell. 1989 Apr 07; 57(1):49-57.
    View in: PubMed
    Score: 0.005
  79. Martinez NJ, Ow MC, Reece-Hoyes JS, Barrasa MI, Ambros VR, Walhout AJ. Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity. Genome Res. 2008 Dec; 18(12):2005-15.
    View in: PubMed
    Score: 0.005
  80. Martinez NJ, Ow MC, Barrasa MI, Hammell M, Sequerra R, Doucette-Stamm L, Roth FP, Ambros VR, Walhout AJ. A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity. Genes Dev. 2008 Sep 15; 22(18):2535-49.
    View in: PubMed
    Score: 0.005
  81. Miska EA, Alvarez-Saavedra E, Abbott AL, Lau NC, Hellman AB, McGonagle SM, Bartel DP, Ambros VR, Horvitz HR. Most Caenorhabditis elegans microRNAs are individually not essential for development or viability. PLoS Genet. 2007 Dec; 3(12):e215.
    View in: PubMed
    Score: 0.005
  82. Hinas A, Reimeg?rd J, Wagner EG, Nellen W, Ambros VR, S?derbom F. The small RNA repertoire of Dictyostelium discoideum and its regulation by components of the RNAi pathway. Nucleic Acids Res. 2007; 35(20):6714-26.
    View in: PubMed
    Score: 0.005
  83. Ambros V, Horvitz HR. The lin-14 locus of Caenorhabditis elegans controls the time of expression of specific postembryonic developmental events. Genes Dev. 1987 Jun; 1(4):398-414.
    View in: PubMed
    Score: 0.005
  84. Long D, Lee R, Williams P, Chan CY, Ambros V, Ding Y. Potent effect of target structure on microRNA function. Nat Struct Mol Biol. 2007 Apr; 14(4):287-94.
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    Score: 0.005
  85. Kuhlmann M, Borisova BE, Kaller M, Larsson P, Stach D, Na J, Eichinger L, Lyko F, Ambros V, S?derbom F, Hammann C, Nellen W. Silencing of retrotransposons in Dictyostelium by DNA methylation and RNAi. Nucleic Acids Res. 2005; 33(19):6405-17.
    View in: PubMed
    Score: 0.004
  86. Ambros V, Horvitz HR. Heterochronic mutants of the nematode Caenorhabditis elegans. Science. 1984 Oct 26; 226(4673):409-16.
    View in: PubMed
    Score: 0.004
  87. Pepper AS, McCane JE, Kemper K, Yeung DA, Lee RC, Ambros V, Moss EG. The C. elegans heterochronic gene lin-46 affects developmental timing at two larval stages and encodes a relative of the scaffolding protein gephyrin. Development. 2004 May; 131(9):2049-59.
    View in: PubMed
    Score: 0.004
  88. Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol Cell. 2000 Apr; 5(4):659-69.
    View in: PubMed
    Score: 0.003
  89. Ambros VR, Chen LB, Buchanan JM. Surface ruffles as markers for studies of cell transformation by Rous sarcoma virus. Proc Natl Acad Sci U S A. 1975 Aug; 72(8):3144-8.
    View in: PubMed
    Score: 0.002
  90. Hodgkin J, Papp A, Pulak R, Ambros V, Anderson P. A new kind of informational suppression in the nematode Caenorhabditis elegans. Genetics. 1989 Oct; 123(2):301-13.
    View in: PubMed
    Score: 0.001
  91. Ruvkun G, Ambros V, Coulson A, Waterston R, Sulston J, Horvitz HR. Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14. Genetics. 1989 Mar; 121(3):501-16.
    View in: PubMed
    Score: 0.001
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