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Susan Swain to Animals

This is a "connection" page, showing publications Susan Swain has written about Animals.
Connection Strength

2.529
  1. Jones MC, Castonguay C, Nanaware PP, Weaver GC, Stadinski B, Kugler-Umana OA, Huseby ES, Stern LJ, McKinstry KK, Strutt TM, Devarajan P, Swain SL. CD4 Effector TCR Avidity for Peptide on APC Determines the Level of Memory Generated. J Immunol. 2023 06 15; 210(12):1950-1961.
    View in: PubMed
    Score: 0.062
  2. Kugler-Umana O, Zhang W, Kuang Y, Liang J, Castonguay CH, Tonkonogy SL, Marshak-Rothstein A, Devarajan P, Swain SL. IgD+ age-associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged. Aging Cell. 2022 10; 21(10):e13705.
    View in: PubMed
    Score: 0.058
  3. Devarajan P, Vong AM, Castonguay CH, Kugler-Umana O, Bautista BL, Jones MC, Kelly KA, Xia J, Swain SL. Strong influenza-induced TFH generation requires CD4 effectors to recognize antigen locally and receive signals from continuing infection. Proc Natl Acad Sci U S A. 2022 02 22; 119(8).
    View in: PubMed
    Score: 0.056
  4. Swain SL, Jones MC, Devarajan P, Xia J, Dutton RW, Strutt TM, McKinstry KK. Durable CD4 T-Cell Memory Generation Depends on Persistence of High Levels of Infection at an Effector Checkpoint that Determines Multiple Fates. Cold Spring Harb Perspect Biol. 2021 11 01; 13(11).
    View in: PubMed
    Score: 0.055
  5. Xia J, Kuang Y, Liang J, Jones M, Swain SL. Influenza Vaccine-Induced CD4 Effectors Require Antigen Recognition at an Effector Checkpoint to Generate CD4 Lung Memory and Antibody Production. J Immunol. 2020 10 15; 205(8):2077-2090.
    View in: PubMed
    Score: 0.051
  6. Kugler-Umana O, Devarajan P, Swain SL. Understanding the Heterogeneous Population of Age-Associated B Cells and Their Contributions to Autoimmunity and Immune Response to Pathogens. Crit Rev Immunol. 2020; 40(4):297-309.
    View in: PubMed
    Score: 0.048
  7. Devarajan P, Jones MC, Kugler-Umana O, Vong AM, Xia J, Swain SL. Pathogen Recognition by CD4 Effectors Drives Key Effector and Most Memory Cell Generation Against Respiratory Virus. Front Immunol. 2018; 9:596.
    View in: PubMed
    Score: 0.043
  8. Swain SL, Kugler-Umana O, Kuang Y, Zhang W. The properties of the unique age-associated B cell subset reveal a shift in strategy of immune response with age. Cell Immunol. 2017 Nov; 321:52-60.
    View in: PubMed
    Score: 0.041
  9. Brahmakshatriya V, Kuang Y, Devarajan P, Xia J, Zhang W, Vong AM, Swain SL. IL-6 Production by TLR-Activated APC Broadly Enhances Aged Cognate CD4 Helper and B Cell Antibody Responses In Vivo. J Immunol. 2017 04 01; 198(7):2819-2833.
    View in: PubMed
    Score: 0.040
  10. Marshall NB, Vong AM, Devarajan P, Brauner MD, Kuang Y, Nayar R, Schutten EA, Castonguay CH, Berg LJ, Nutt SL, Swain SL. NKG2C/E Marks the Unique Cytotoxic CD4 T Cell Subset, ThCTL, Generated by Influenza Infection. J Immunol. 2017 02 01; 198(3):1142-1155.
    View in: PubMed
    Score: 0.039
  11. Bautista BL, Devarajan P, McKinstry KK, Strutt TM, Vong AM, Jones MC, Kuang Y, Mott D, Swain SL. Short-Lived Antigen Recognition but Not Viral Infection at a Defined Checkpoint Programs Effector CD4 T Cells To Become Protective Memory. J Immunol. 2016 11 15; 197(10):3936-3949.
    View in: PubMed
    Score: 0.039
  12. Strutt TM, McKinstry KK, Kuang Y, Finn CM, Hwang JH, Dhume K, Sell S, Swain SL. Direct IL-6 Signals Maximize Protective Secondary CD4 T Cell Responses against Influenza. J Immunol. 2016 10 15; 197(8):3260-3270.
    View in: PubMed
    Score: 0.039
  13. Sell S, Guest I, McKinstry KK, Strutt TM, Kohlmeier JE, Brincks E, Tighe M, Blackman MA, Woodland DL, Dutton RW, Swain SL. Intraepithelial T-cell cytotoxicity, induced bronchus-associated lymphoid tissue, and proliferation of pneumocytes in experimental mouse models of influenza. Viral Immunol. 2014 Dec; 27(10):484-96.
    View in: PubMed
    Score: 0.034
  14. McKinstry KK, Strutt TM, Bautista B, Zhang W, Kuang Y, Cooper AM, Swain SL. Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2. Nat Commun. 2014 Nov 05; 5:5377.
    View in: PubMed
    Score: 0.034
  15. Zhang W, Brahmakshatriya V, Swain SL. CD4 T cell defects in the aged: causes, consequences and strategies to circumvent. Exp Gerontol. 2014 Jun; 54:67-70.
    View in: PubMed
    Score: 0.032
  16. Strutt TM, McKinstry KK, Marshall NB, Vong AM, Dutton RW, Swain SL. Multipronged CD4(+) T-cell effector and memory responses cooperate to provide potent immunity against respiratory virus. Immunol Rev. 2013 Sep; 255(1):149-64.
    View in: PubMed
    Score: 0.031
  17. Strutt TM, McKinstry KK, Kuang Y, Bradley LM, Swain SL. Memory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectors. Proc Natl Acad Sci U S A. 2012 Sep 18; 109(38):E2551-60.
    View in: PubMed
    Score: 0.029
  18. McKinstry KK, Strutt TM, Kuang Y, Brown DM, Sell S, Dutton RW, Swain SL. Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms. J Clin Invest. 2012 Aug; 122(8):2847-56.
    View in: PubMed
    Score: 0.029
  19. Haynes L, Swain SL. Aged-related shifts in T cell homeostasis lead to intrinsic T cell defects. Semin Immunol. 2012 Oct; 24(5):350-5.
    View in: PubMed
    Score: 0.028
  20. Brown DM, Lee S, Garcia-Hernandez Mde L, Swain SL. Multifunctional CD4 cells expressing gamma interferon and perforin mediate protection against lethal influenza virus infection. J Virol. 2012 Jun; 86(12):6792-803.
    View in: PubMed
    Score: 0.028
  21. Swain SL, McKinstry KK, Strutt TM. Expanding roles for CD4? T cells in immunity to viruses. Nat Rev Immunol. 2012 Jan 20; 12(2):136-48.
    View in: PubMed
    Score: 0.028
  22. Marshall NB, Swain SL. Cytotoxic CD4 T cells in antiviral immunity. J Biomed Biotechnol. 2011; 2011:954602.
    View in: PubMed
    Score: 0.028
  23. Strutt TM, McKinstry KK, Swain SL. Control of innate immunity by memory CD4 T cells. Adv Exp Med Biol. 2011; 780:57-68.
    View in: PubMed
    Score: 0.026
  24. Jones SC, Brahmakshatriya V, Huston G, Dibble J, Swain SL. TLR-activated dendritic cells enhance the response of aged naive CD4 T cells via an IL-6-dependent mechanism. J Immunol. 2010 Dec 01; 185(11):6783-94.
    View in: PubMed
    Score: 0.026
  25. Tsukamoto H, Huston GE, Dibble J, Duso DK, Swain SL. Bim dictates naive CD4 T cell lifespan and the development of age-associated functional defects. J Immunol. 2010 Oct 15; 185(8):4535-44.
    View in: PubMed
    Score: 0.025
  26. Strutt TM, McKinstry KK, Dibble JP, Winchell C, Kuang Y, Curtis JD, Huston G, Dutton RW, Swain SL. Memory CD4+ T cells induce innate responses independently of pathogen. Nat Med. 2010 May; 16(5):558-64, 1p following 564.
    View in: PubMed
    Score: 0.025
  27. McKinstry KK, Strutt TM, Swain SL. The potential of CD4 T-cell memory. Immunology. 2010 May; 130(1):1-9.
    View in: PubMed
    Score: 0.025
  28. Tsukamoto H, Clise-Dwyer K, Huston GE, Duso DK, Buck AL, Johnson LL, Haynes L, Swain SL. Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects. Proc Natl Acad Sci U S A. 2009 Oct 27; 106(43):18333-8.
    View in: PubMed
    Score: 0.024
  29. Dorshkind K, Swain S. Age-associated declines in immune system development and function: causes, consequences, and reversal. Curr Opin Immunol. 2009 Aug; 21(4):404-7.
    View in: PubMed
    Score: 0.023
  30. McKinstry KK, Strutt TM, Buck A, Curtis JD, Dibble JP, Huston G, Tighe M, Hamada H, Sell S, Dutton RW, Swain SL. IL-10 deficiency unleashes an influenza-specific Th17 response and enhances survival against high-dose challenge. J Immunol. 2009 Jun 15; 182(12):7353-63.
    View in: PubMed
    Score: 0.023
  31. Brown DM, Kamperschroer C, Dilzer AM, Roberts DM, Swain SL. IL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells. Cell Immunol. 2009; 257(1-2):69-79.
    View in: PubMed
    Score: 0.023
  32. Swain SL, Nikolich-Zugich J. Key research opportunities in immune system aging. J Gerontol A Biol Sci Med Sci. 2009 Feb; 64(2):183-6.
    View in: PubMed
    Score: 0.023
  33. Strutt TM, McKinstry KK, Swain SL. Functionally diverse subsets in CD4 T cell responses against influenza. J Clin Immunol. 2009 Mar; 29(2):145-50.
    View in: PubMed
    Score: 0.022
  34. Kamperschroer C, Roberts DM, Zhang Y, Weng NP, Swain SL. SAP enables T cells to help B cells by a mechanism distinct from Th cell programming or CD40 ligand regulation. J Immunol. 2008 Sep 15; 181(6):3994-4003.
    View in: PubMed
    Score: 0.022
  35. Jones SC, Clise-Dwyer K, Huston G, Dibble J, Eaton S, Haynes L, Swain SL. Impact of post-thymic cellular longevity on the development of age-associated CD4+ T cell defects. J Immunol. 2008 Apr 01; 180(7):4465-75.
    View in: PubMed
    Score: 0.021
  36. McKinstry KK, Strutt TM, Swain SL. The effector to memory transition of CD4 T cells. Immunol Res. 2008; 40(2):114-27.
    View in: PubMed
    Score: 0.021
  37. McKinstry KK, Golech S, Lee WH, Huston G, Weng NP, Swain SL. Rapid default transition of CD4 T cell effectors to functional memory cells. J Exp Med. 2007 Sep 03; 204(9):2199-211.
    View in: PubMed
    Score: 0.021
  38. Jelley-Gibbs DM, Dibble JP, Brown DM, Strutt TM, McKinstry KK, Swain SL. Persistent depots of influenza antigen fail to induce a cytotoxic CD8 T cell response. J Immunol. 2007 Jun 15; 178(12):7563-70.
    View in: PubMed
    Score: 0.020
  39. Clise-Dwyer K, Huston GE, Buck AL, Duso DK, Swain SL. Environmental and intrinsic factors lead to antigen unresponsiveness in CD4(+) recent thymic emigrants from aged mice. J Immunol. 2007 Feb 01; 178(3):1321-31.
    View in: PubMed
    Score: 0.020
  40. Agrewala JN, Brown DM, Lepak NM, Duso D, Huston G, Swain SL. Unique ability of activated CD4+ T cells but not rested effectors to migrate to non-lymphoid sites in the absence of inflammation. J Biol Chem. 2007 Mar 02; 282(9):6106-15.
    View in: PubMed
    Score: 0.020
  41. Kamperschroer C, Dibble JP, Meents DL, Schwartzberg PL, Swain SL. SAP is required for Th cell function and for immunity to influenza. J Immunol. 2006 Oct 15; 177(8):5317-27.
    View in: PubMed
    Score: 0.019
  42. Brown DM, Dilzer AM, Meents DL, Swain SL. CD4 T cell-mediated protection from lethal influenza: perforin and antibody-mediated mechanisms give a one-two punch. J Immunol. 2006 Sep 01; 177(5):2888-98.
    View in: PubMed
    Score: 0.019
  43. Swain SL, Agrewala JN, Brown DM, Jelley-Gibbs DM, Golech S, Huston G, Jones SC, Kamperschroer C, Lee WH, McKinstry KK, Rom?n E, Strutt T, Weng NP. CD4+ T-cell memory: generation and multi-faceted roles for CD4+ T cells in protective immunity to influenza. Immunol Rev. 2006 Jun; 211:8-22.
    View in: PubMed
    Score: 0.019
  44. Swain SL. Thanks for the memory! J Immunol. 2005 Oct 15; 175(8):4823-6.
    View in: PubMed
    Score: 0.018
  45. Swain S, Clise-Dwyer K, Haynes L. Homeostasis and the age-associated defect of CD4 T cells. Semin Immunol. 2005 Oct; 17(5):370-7.
    View in: PubMed
    Score: 0.018
  46. Jelley-Gibbs DM, Brown DM, Dibble JP, Haynes L, Eaton SM, Swain SL. Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation. J Exp Med. 2005 Sep 05; 202(5):697-706.
    View in: PubMed
    Score: 0.018
  47. Jelley-Gibbs DM, Dibble JP, Filipson S, Haynes L, Kemp RA, Swain SL. Repeated stimulation of CD4 effector T cells can limit their protective function. J Exp Med. 2005 Apr 04; 201(7):1101-12.
    View in: PubMed
    Score: 0.017
  48. Haynes L, Eaton SM, Burns EM, Randall TD, Swain SL. Newly generated CD4 T cells in aged animals do not exhibit age-related defects in response to antigen. J Exp Med. 2005 Mar 21; 201(6):845-51.
    View in: PubMed
    Score: 0.017
  49. Brown DM, Rom?n E, Swain SL. CD4 T cell responses to influenza infection. Semin Immunol. 2004 Jun; 16(3):171-7.
    View in: PubMed
    Score: 0.016
  50. Haynes L, Eaton SM, Burns EM, Rincon M, Swain SL. Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo. J Immunol. 2004 May 01; 172(9):5194-9.
    View in: PubMed
    Score: 0.016
  51. Swain SL, Dutton RW, Woodland DL. T cell responses to influenza virus infection: effector and memory cells. Viral Immunol. 2004; 17(2):197-209.
    View in: PubMed
    Score: 0.016
  52. Li J, Huston G, Swain SL. IL-7 promotes the transition of CD4 effectors to persistent memory cells. J Exp Med. 2003 Dec 15; 198(12):1807-15.
    View in: PubMed
    Score: 0.016
  53. Haynes L, Eaton SM, Burns EM, Randall TD, Swain SL. CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):15053-8.
    View in: PubMed
    Score: 0.016
  54. Swain SL. Regulation of the generation and maintenance of T-cell memory: a direct, default pathway from effectors to memory cells. Microbes Infect. 2003 Mar; 5(3):213-9.
    View in: PubMed
    Score: 0.015
  55. Rom?n E, Miller E, Harmsen A, Wiley J, Von Andrian UH, Huston G, Swain SL. CD4 effector T cell subsets in the response to influenza: heterogeneity, migration, and function. J Exp Med. 2002 Oct 07; 196(7):957-68.
    View in: PubMed
    Score: 0.015
  56. Yen MH, Lepak N, Swain SL. Induction of CD4 T cell changes in murine AIDS is dependent on costimulation and involves a dysregulation of homeostasis. J Immunol. 2002 Jul 15; 169(2):722-31.
    View in: PubMed
    Score: 0.014
  57. Dhume K, Finn CM, Devarajan P, Singh A, Tejero JD, Prokop E, Strutt TM, Sell S, Swain SL, McKinstry KK. Bona Fide Th17 Cells without Th1 Functional Plasticity Protect against Influenza. J Immunol. 2022 04 15; 208(8):1998-2007.
    View in: PubMed
    Score: 0.014
  58. Haynes L, Eaton SM, Swain SL. Effect of age on naive CD4 responses: impact on effector generation and memory development. Springer Semin Immunopathol. 2002; 24(1):53-60.
    View in: PubMed
    Score: 0.014
  59. Swain SL, Agrewala JN, Brown DM, Rom?n E. Regulation of memory CD4 T cells: generation, localization and persistence. Adv Exp Med Biol. 2002; 512:113-20.
    View in: PubMed
    Score: 0.014
  60. Swain SL. Interleukin 18: tipping the balance towards a T helper cell 1 response. J Exp Med. 2001 Aug 06; 194(3):F11-4.
    View in: PubMed
    Score: 0.014
  61. Hu H, Huston G, Duso D, Lepak N, Roman E, Swain SL. CD4(+) T cell effectors can become memory cells with high efficiency and without further division. Nat Immunol. 2001 Aug; 2(8):705-10.
    View in: PubMed
    Score: 0.014
  62. Harris DP, Koch S, Mullen LM, Swain SL. B cell immunodeficiency fails to develop in CD4-deficient mice infected with BM5: murine AIDS as a multistep disease. J Immunol. 2001 May 15; 166(10):6041-9.
    View in: PubMed
    Score: 0.013
  63. Cauley LS, Miller EE, Yen M, Swain SL. Superantigen-induced CD4 T cell tolerance mediated by myeloid cells and IFN-gamma. J Immunol. 2000 Dec 01; 165(11):6056-66.
    View in: PubMed
    Score: 0.013
  64. Jelley-Gibbs DM, Lepak NM, Yen M, Swain SL. Two distinct stages in the transition from naive CD4 T cells to effectors, early antigen-dependent and late cytokine-driven expansion and differentiation. J Immunol. 2000 Nov 01; 165(9):5017-26.
    View in: PubMed
    Score: 0.013
  65. Alam F, Singh A, Flores-Malavet V, Sell S, Cooper AM, Swain SL, McKinstry KK, Strutt TM. CD25-Targeted IL-2 Signals Promote Improved Outcomes of Influenza Infection and Boost Memory CD4 T Cell Formation. J Immunol. 2020 06 15; 204(12):3307-3314.
    View in: PubMed
    Score: 0.012
  66. Swain SL. CD4 T-cell memory can persist in the absence of class II. Philos Trans R Soc Lond B Biol Sci. 2000 Mar 29; 355(1395):407-11.
    View in: PubMed
    Score: 0.012
  67. Rogers PR, Dubey C, Swain SL. Qualitative changes accompany memory T cell generation: faster, more effective responses at lower doses of antigen. J Immunol. 2000 Mar 01; 164(5):2338-46.
    View in: PubMed
    Score: 0.012
  68. Haynes L, Eaton SM, Swain SL. The defects in effector generation associated with aging can be reversed by addition of IL-2 but not other related gamma(c)-receptor binding cytokines. Vaccine. 2000 Feb 25; 18(16):1649-53.
    View in: PubMed
    Score: 0.012
  69. Cerwenka A, Swain SL. TGF-beta1: immunosuppressant and viability factor for T lymphocytes. Microbes Infect. 1999 Dec; 1(15):1291-6.
    View in: PubMed
    Score: 0.012
  70. Swain SL, Hu H, Huston G. Class II-independent generation of CD4 memory T cells from effectors. Science. 1999 Nov 12; 286(5443):1381-3.
    View in: PubMed
    Score: 0.012
  71. Daniels KA, O'Donnell CL, Castonguay C, Strutt TM, McKinstry KK, Swain SL, Welsh RM. Virus-induced natural killer cell lysis of T cell subsets. Virology. 2020 01 02; 539:26-37.
    View in: PubMed
    Score: 0.012
  72. Haynes L, Linton PJ, Eaton SM, Tonkonogy SL, Swain SL. Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice. J Exp Med. 1999 Oct 04; 190(7):1013-24.
    View in: PubMed
    Score: 0.012
  73. McKinstry KK, Alam F, Flores-Malavet V, Nagy MZ, Sell S, Cooper AM, Swain SL, Strutt TM. Memory CD4 T cell-derived IL-2 synergizes with viral infection to exacerbate lung inflammation. PLoS Pathog. 2019 08; 15(8):e1007989.
    View in: PubMed
    Score: 0.012
  74. Swain SL. Helper T cell differentiation. Curr Opin Immunol. 1999 Apr; 11(2):180-5.
    View in: PubMed
    Score: 0.011
  75. Rogers PR, Huston G, Swain SL. High antigen density and IL-2 are required for generation of CD4 effectors secreting Th1 rather than Th0 cytokines. J Immunol. 1998 Oct 15; 161(8):3844-52.
    View in: PubMed
    Score: 0.011
  76. Carter LL, Swain SL. From naive to memory. Development and regulation of CD4+ T cell responses. Immunol Res. 1998 Aug; 18(1):1-13.
    View in: PubMed
    Score: 0.011
  77. Carter LL, Zhang X, Dubey C, Rogers P, Tsui L, Swain SL. Regulation of T cell subsets from naive to memory. J Immunother. 1998 May; 21(3):181-7.
    View in: PubMed
    Score: 0.011
  78. Dutton RW, Bradley LM, Swain SL. T cell memory. Annu Rev Immunol. 1998; 16:201-23.
    View in: PubMed
    Score: 0.011
  79. Strutt TM, Dhume K, Finn CM, Hwang JH, Castonguay C, Swain SL, McKinstry KK. IL-15 supports the generation of protective lung-resident memory CD4 T cells. Mucosal Immunol. 2018 05; 11(3):668-680.
    View in: PubMed
    Score: 0.010
  80. Cauley LS, Cauley KA, Shub F, Huston G, Swain SL. Transferable anergy: superantigen treatment induces CD4+ T cell tolerance that is reversible and requires CD4-CD8- cells and interferon gamma. J Exp Med. 1997 Jul 07; 186(1):71-81.
    View in: PubMed
    Score: 0.010
  81. Zhang X, Brunner T, Carter L, Dutton RW, Rogers P, Bradley L, Sato T, Reed JC, Green D, Swain SL. Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/FasL-mediated apoptosis. J Exp Med. 1997 May 19; 185(10):1837-49.
    View in: PubMed
    Score: 0.010
  82. Haynes L, Linton PJ, Swain SL. Age-related changes in CD4 T cells of T cell receptor transgenic mice. Mech Ageing Dev. 1997 Feb; 93(1-3):95-105.
    View in: PubMed
    Score: 0.010
  83. Linton PJ, Haynes L, Klinman NR, Swain SL. Antigen-independent changes in naive CD4 T cells with aging. J Exp Med. 1996 Nov 01; 184(5):1891-900.
    View in: PubMed
    Score: 0.010
  84. Dubey C, Croft M, Swain SL. Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals. J Immunol. 1996 Oct 15; 157(8):3280-9.
    View in: PubMed
    Score: 0.010
  85. Muralidhar G, Koch S, Broome HE, Swain SL. TCR triggering of anergic CD4 T cells in murine AIDS induces apoptosis rather than cytokine synthesis and proliferation. J Immunol. 1996 Jul 15; 157(2):625-35.
    View in: PubMed
    Score: 0.010
  86. Zhou X, Hopkins JW, Wang C, Brahmakshatriya V, Swain SL, Kuchel GA, Haynes L, McElhaney JE. IL-2 and IL-6 cooperate to enhance the generation of influenza-specific CD8 T cells responding to live influenza virus in aged mice and humans. Oncotarget. 2016 Jun 28; 7(26):39171-39183.
    View in: PubMed
    Score: 0.009
  87. Tinoco R, Carrette F, Barraza ML, Otero DC, Maga?a J, Bosenberg MW, Swain SL, Bradley LM. PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion. Immunity. 2016 05 17; 44(5):1190-203.
    View in: PubMed
    Score: 0.009
  88. Swain SL, Croft M, Dubey C, Haynes L, Rogers P, Zhang X, Bradley LM. From naive to memory T cells. Immunol Rev. 1996 Apr; 150:143-67.
    View in: PubMed
    Score: 0.009
  89. Brodeur TY, Robidoux TE, Weinstein JS, Craft J, Swain SL, Marshak-Rothstein A. IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells. J Immunol. 2015 Dec 01; 195(11):5251-60.
    View in: PubMed
    Score: 0.009
  90. Zhang X, Giangreco L, Broome HE, Dargan CM, Swain SL. Control of CD4 effector fate: transforming growth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion. J Exp Med. 1995 Sep 01; 182(3):699-709.
    View in: PubMed
    Score: 0.009
  91. Torrado E, Fountain JJ, Liao M, Tighe M, Reiley WW, Lai RP, Meintjes G, Pearl JE, Chen X, Zak DE, Thompson EG, Aderem A, Ghilardi N, Solache A, McKinstry KK, Strutt TM, Wilkinson RJ, Swain SL, Cooper AM. Interleukin 27R regulates CD4+ T cell phenotype and impacts protective immunity during Mycobacterium tuberculosis infection. J Exp Med. 2015 Aug 24; 212(9):1449-63.
    View in: PubMed
    Score: 0.009
  92. Bradley LM, Yoshimoto K, Swain SL. The cytokines IL-4, IFN-gamma, and IL-12 regulate the development of subsets of memory effector helper T cells in vitro. J Immunol. 1995 Aug 15; 155(4):1713-24.
    View in: PubMed
    Score: 0.009
  93. Swain SL. T-cell subsets. Who does the polarizing? Curr Biol. 1995 Aug 01; 5(8):849-51.
    View in: PubMed
    Score: 0.009
  94. Dubey C, Croft M, Swain SL. Costimulatory requirements of naive CD4+ T cells. ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response. J Immunol. 1995 Jul 01; 155(1):45-57.
    View in: PubMed
    Score: 0.009
  95. Croft M, Swain SL. Recently activated naive CD4 T cells can help resting B cells, and can produce sufficient autocrine IL-4 to drive differentiation to secretion of T helper 2-type cytokines. J Immunol. 1995 May 01; 154(9):4269-82.
    View in: PubMed
    Score: 0.009
  96. Swain SL. CD4 T cell development and cytokine polarization: an overview. J Leukoc Biol. 1995 May; 57(5):795-8.
    View in: PubMed
    Score: 0.009
  97. Tsukamoto H, Senju S, Matsumura K, Swain SL, Nishimura Y. IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age. Nat Commun. 2015 Apr 07; 6:6702.
    View in: PubMed
    Score: 0.009
  98. Bradley LM, Watson SR, Swain SL. Entry of naive CD4 T cells into peripheral lymph nodes requires L-selectin. J Exp Med. 1994 Dec 01; 180(6):2401-6.
    View in: PubMed
    Score: 0.009
  99. Swain SL. Generation and in vivo persistence of polarized Th1 and Th2 memory cells. Immunity. 1994 Oct; 1(7):543-52.
    View in: PubMed
    Score: 0.008
  100. Duncan DD, Swain SL. Role of antigen-presenting cells in the polarized development of helper T cell subsets: evidence for differential cytokine production by Th0 cells in response to antigen presentation by B cells and macrophages. Eur J Immunol. 1994 Oct; 24(10):2506-14.
    View in: PubMed
    Score: 0.008
  101. Koch S, Muralidhar G, Swain SL. Both naive and memory CD4 T cell subsets become anergic during MAIDS and each subset can sustain disease. J Immunol. 1994 Jun 01; 152(11):5548-56.
    View in: PubMed
    Score: 0.008
  102. Nayar R, Schutten E, Bautista B, Daniels K, Prince AL, Enos M, Brehm MA, Swain SL, Welsh RM, Berg LJ. Graded levels of IRF4 regulate CD8+ T cell differentiation and expansion, but not attrition, in response to acute virus infection. J Immunol. 2014 Jun 15; 192(12):5881-93.
    View in: PubMed
    Score: 0.008
  103. Croft M, Bradley LM, Swain SL. Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells. J Immunol. 1994 Mar 15; 152(6):2675-85.
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    Score: 0.008
  104. Tonkonogy SL, Swain SL. Distinct lymphokine production by CD4+ T cells isolated from mucosal and systemic lymphoid organs. Immunology. 1993 Dec; 80(4):574-80.
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    Score: 0.008
  105. Jain N, Miu B, Jiang JK, McKinstry KK, Prince A, Swain SL, Greiner DL, Thomas CJ, Sanderson MJ, Berg LJ, Kang J. CD28 and ITK signals regulate autoreactive T cell trafficking. Nat Med. 2013 Dec; 19(12):1632-7.
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    Score: 0.008
  106. Swain SL. IL4 dictates T-cell differentiation. Res Immunol. 1993 Oct; 144(8):616-20.
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    Score: 0.008
  107. Swain SL. Effector functions of helper T cells. J Immunother Emphasis Tumor Immunol. 1993 Aug; 14(2):150-4.
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    Score: 0.008
  108. McKinstry KK, Dutton RW, Swain SL, Strutt TM. Memory CD4 T cell-mediated immunity against influenza A virus: more than a little helpful. Arch Immunol Ther Exp (Warsz). 2013 Oct; 61(5):341-53.
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    Score: 0.008
  109. Bradley LM, Croft M, Swain SL. T-cell memory: new perspectives. Immunol Today. 1993 May; 14(5):197-9.
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    Score: 0.008
  110. Bradley LM, Duncan DD, Yoshimoto K, Swain SL. Memory effectors: a potent, IL-4-secreting helper T cell population that develops in vivo after restimulation with antigen. J Immunol. 1993 Apr 15; 150(8 Pt 1):3119-30.
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    Score: 0.008
  111. Hamada H, Bassity E, Flies A, Strutt TM, Garcia-Hernandez Mde L, McKinstry KK, Zou T, Swain SL, Dutton RW. Multiple redundant effector mechanisms of CD8+ T cells protect against influenza infection. J Immunol. 2013 Jan 01; 190(1):296-306.
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    Score: 0.007
  112. Croft M, Swain SL. Analysis of CD4+ T cells that provide contact-dependent bystander help to B cells. J Immunol. 1992 Nov 15; 149(10):3157-65.
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    Score: 0.007
  113. Croft M, Duncan DD, Swain SL. Response of naive antigen-specific CD4+ T cells in vitro: characteristics and antigen-presenting cell requirements. J Exp Med. 1992 Nov 01; 176(5):1431-7.
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    Score: 0.007
  114. Pearl JE, Torrado E, Tighe M, Fountain JJ, Solache A, Strutt T, Swain S, Appelberg R, Cooper AM. Nitric oxide inhibits the accumulation of CD4+CD44hiTbet+CD69lo T cells in mycobacterial infection. Eur J Immunol. 2012 Dec; 42(12):3267-79.
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    Score: 0.007
  115. Muralidhar G, Koch S, Haas M, Swain SL. CD4 T cells in murine acquired immunodeficiency syndrome: polyclonal progression to anergy. J Exp Med. 1992 Jun 01; 175(6):1589-99.
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    Score: 0.007
  116. Swain SL, Bradley LM. Helper T cell memory: more questions than answers. Semin Immunol. 1992 Feb; 4(1):59-68.
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    Score: 0.007
  117. Bradley LM, Atkins GG, Swain SL. Long-term CD4+ memory T cells from the spleen lack MEL-14, the lymph node homing receptor. J Immunol. 1992 Jan 15; 148(2):324-31.
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    Score: 0.007
  118. Croft M, Swain SL. B cell response to T helper cell subsets. II. Both the stage of T cell differentiation and the cytokines secreted determine the extent and nature of helper activity. J Immunol. 1991 Dec 01; 147(11):3679-89.
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    Score: 0.007
  119. Swain SL, Huston G, Tonkonogy S, Weinberg A. Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype. J Immunol. 1991 Nov 01; 147(9):2991-3000.
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    Score: 0.007
  120. Swain SL, Bradley LM, Croft M, Tonkonogy S, Atkins G, Weinberg AD, Duncan DD, Hedrick SM, Dutton RW, Huston G. Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development. Immunol Rev. 1991 Oct; 123:115-44.
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    Score: 0.007
  121. Bradley LM, Duncan DD, Tonkonogy S, Swain SL. Characterization of antigen-specific CD4+ effector T cells in vivo: immunization results in a transient population of MEL-14-, CD45RB- helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon gamma. J Exp Med. 1991 Sep 01; 174(3):547-59.
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    Score: 0.007
  122. An J, Golech S, Klaewsongkram J, Zhang Y, Subedi K, Huston GE, Wood WH, Wersto RP, Becker KG, Swain SL, Weng N. Kr?ppel-like factor 4 (KLF4) directly regulates proliferation in thymocyte development and IL-17 expression during Th17 differentiation. FASEB J. 2011 Oct; 25(10):3634-45.
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    Score: 0.007
  123. Croft M, Swain SL. B cell response to fresh and effector T helper cells. Role of cognate T-B interaction and the cytokines IL-2, IL-4, and IL-6. J Immunol. 1991 Jun 15; 146(12):4055-64.
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    Score: 0.007
  124. Swain SL. Lymphokines and the immune response: the central role of interleukin-2. Curr Opin Immunol. 1991 Jun; 3(3):304-10.
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    Score: 0.007
  125. Swain SL, Dutton RW. Is autoimmunity good for you? The Molecular Basis of Recognition in the Immune System sponsored by the European Federation of Immunological Societies, Edinburgh, UK, September 10-12, 1990. New Biol. 1991 Feb; 3(2):117-20.
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    Score: 0.007
  126. Kubota E, McKenzie DT, Dutton RW, Swain SL. Role of T cells in the B-cell response: glutaraldehyde-fixed T-helper hybridoma cells synergize with the lymphokine IL-4 to induce B-cell activation and proliferation. Immunology. 1991 Jan; 72(1):40-7.
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    Score: 0.006
  127. Swain SL. Regulation of the development of distinct subsets of CD4+ T cells. Res Immunol. 1991 Jan; 142(1):14-8.
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    Score: 0.006
  128. Swain SL. Regulation of the development of helper T cell subsets. Immunol Res. 1991; 10(3-4):177-82.
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    Score: 0.006
  129. Swain SL, Weinberg AD, English M, Huston G. IL-4 directs the development of Th2-like helper effectors. J Immunol. 1990 Dec 01; 145(11):3796-806.
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    Score: 0.006
  130. Weinberg AD, Swain SL. IL-2 receptor (Tac antigen) protein expression is down-regulated by the 5'-untranslated region of the mRNA. J Immunol. 1990 Jun 15; 144(12):4712-20.
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    Score: 0.006
  131. Swain SL, Croft M. Critical role of cognate interactions in the response of small, high-density B cells. Res Immunol. 1990 May-Jun; 141(4-5):431-40.
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    Score: 0.006
  132. Swain SL, Weinberg AD, English M. CD4+ T cell subsets. Lymphokine secretion of memory cells and of effector cells that develop from precursors in vitro. J Immunol. 1990 Mar 01; 144(5):1788-99.
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    Score: 0.006
  133. Weinberg AD, English M, Swain SL. Distinct regulation of lymphokine production is found in fresh versus in vitro primed murine helper T cells. J Immunol. 1990 Mar 01; 144(5):1800-7.
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    Score: 0.006
  134. Maue AC, Yager EJ, Swain SL, Woodland DL, Blackman MA, Haynes L. T-cell immunosenescence: lessons learned from mouse models of aging. Trends Immunol. 2009 Jul; 30(7):301-5.
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    Score: 0.006
  135. Tonkonogy SL, McKenzie DT, Swain SL. Regulation of isotype production by IL-4 and IL-5. Effects of lymphokines on Ig production depend on the state of activation of the responding B cells. J Immunol. 1989 Jun 15; 142(12):4351-60.
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    Score: 0.006
  136. Hamada H, Garcia-Hernandez Mde L, Reome JB, Misra SK, Strutt TM, McKinstry KK, Cooper AM, Swain SL, Dutton RW. Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge. J Immunol. 2009 Mar 15; 182(6):3469-81.
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    Score: 0.006
  137. Swain SL. Role of helper T cells in the B cell response. Contrib Microbiol Immunol. 1989; 11:43-72.
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    Score: 0.006
  138. Swain SL, McKenzie DT, Weinberg AD, Hancock W. Characterization of T helper 1 and 2 cell subsets in normal mice. Helper T cells responsible for IL-4 and IL-5 production are present as precursors that require priming before they develop into lymphokine-secreting cells. J Immunol. 1988 Nov 15; 141(10):3445-55.
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    Score: 0.006
  139. Eaton SM, Maue AC, Swain SL, Haynes L. Bone marrow precursor cells from aged mice generate CD4 T cells that function well in primary and memory responses. J Immunol. 2008 Oct 01; 181(7):4825-31.
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    Score: 0.006
  140. Swain SL, Dutton RW, McKenzie D, Helstrom H, English M. Role of antigen in the B cell response. Specific antigen and the lymphokine IL-5 synergize to drive B cell lymphoma proliferation and differentiation to Ig secretion. J Immunol. 1988 Jun 15; 140(12):4224-30.
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    Score: 0.005
  141. Tonkonogy SL, Swain SL. Stimulation of gut-associated lymphoid cells by IL-4 and B-cell growth factor II. Immunology. 1988 May; 64(1):155-61.
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    Score: 0.005
  142. Swain SL, McKenzie DT, Dutton RW, Tonkonogy SL, English M. The role of IL4 and IL5: characterization of a distinct helper T cell subset that makes IL4 and IL5 (Th2) and requires priming before induction of lymphokine secretion. Immunol Rev. 1988 Feb; 102:77-105.
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    Score: 0.005
  143. Hinshaw-Makepeace J, Huston G, Fortner KA, Russell JQ, Holoch D, Swain S, Budd RC. c-FLIP(S) reduces activation of caspase and NF-kappaB pathways and decreases T cell survival. Eur J Immunol. 2008 Jan; 38(1):54-63.
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    Score: 0.005
  144. Kupfer A, Singer SJ, Janeway CA, Swain SL. Coclustering of CD4 (L3T4) molecule with the T-cell receptor is induced by specific direct interaction of helper T cells and antigen-presenting cells. Proc Natl Acad Sci U S A. 1987 Aug; 84(16):5888-92.
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    Score: 0.005
  145. Li X, McKinstry KK, Swain SL, Dalton DK. IFN-gamma acts directly on activated CD4+ T cells during mycobacterial infection to promote apoptosis by inducing components of the intracellular apoptosis machinery and by inducing extracellular proapoptotic signals. J Immunol. 2007 Jul 15; 179(2):939-49.
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    Score: 0.005
  146. Dienz O, Eaton SM, Krahl TJ, Diehl S, Charland C, Dodge J, Swain SL, Budd RC, Haynes L, Rincon M. Accumulation of NFAT mediates IL-2 expression in memory, but not na?ve, CD4+ T cells. Proc Natl Acad Sci U S A. 2007 Apr 24; 104(17):7175-80.
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    Score: 0.005
  147. Khader SA, Bell GK, Pearl JE, Fountain JJ, Rangel-Moreno J, Cilley GE, Shen F, Eaton SM, Gaffen SL, Swain SL, Locksley RM, Haynes L, Randall TD, Cooper AM. IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol. 2007 Apr; 8(4):369-77.
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    Score: 0.005
  148. Powell TJ, Strutt T, Reome J, Hollenbaugh JA, Roberts AD, Woodland DL, Swain SL, Dutton RW. Priming with cold-adapted influenza A does not prevent infection but elicits long-lived protection against supralethal challenge with heterosubtypic virus. J Immunol. 2007 Jan 15; 178(2):1030-8.
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    Score: 0.005
  149. Swain SL, Dutton RW. B cell growth factor interactions. Adv Exp Med Biol. 1987; 213:215-25.
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    Score: 0.005
  150. Dutton RW, Swain SL, Woodland DL. Vaccines against pandemic influenza. Viral Immunol. 2007; 20(2):326-7.
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    Score: 0.005
  151. Khader SA, Partida-Sanchez S, Bell G, Jelley-Gibbs DM, Swain S, Pearl JE, Ghilardi N, Desauvage FJ, Lund FE, Cooper AM. Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection. J Exp Med. 2006 Jul 10; 203(7):1805-15.
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    Score: 0.005
  152. Kamperschroer C, Swain SL, Grussenmeyer T, Lefkovits I. SAP deficiency results in a striking alteration of the protein profile in activated CD4 T cells. J Proteome Res. 2006 Jul; 5(7):1785-91.
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    Score: 0.005
  153. Crowe SR, Miller SC, Brown DM, Adams PS, Dutton RW, Harmsen AG, Lund FE, Randall TD, Swain SL, Woodland DL. Uneven distribution of MHC class II epitopes within the influenza virus. Vaccine. 2006 Jan 23; 24(4):457-67.
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    Score: 0.004
  154. Haynes L, Swain SL, Cambier J, Fulder R. Aging and immune function. Summary of a workshop held at Trudeau Institute, Saranac Lake, NY. Mech Ageing Dev. 2005 Jun-Jul; 126(6-7):822-5.
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    Score: 0.004
  155. Swain SL. Role of BCGFII in the differentiation to antibody secretion normal and tumor B cells. J Immunol. 1985 Jun; 134(6):3934-43.
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    Score: 0.004
  156. Misra RS, Jelley-Gibbs DM, Russell JQ, Huston G, Swain SL, Budd RC. Effector CD4+ T cells generate intermediate caspase activity and cleavage of caspase-8 substrates. J Immunol. 2005 Apr 01; 174(7):3999-4009.
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    Score: 0.004
  157. Lyadova IV, Oberdorf S, Kapina MA, Apt AS, Swain SL, Sayles PC. CD4 T cells producing IFN-gamma in the lungs of mice challenged with mycobacteria express a CD27-negative phenotype. Clin Exp Immunol. 2004 Oct; 138(1):21-9.
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    Score: 0.004
  158. Powell TJ, Brown DM, Hollenbaugh JA, Charbonneau T, Kemp RA, Swain SL, Dutton RW. CD8+ T cells responding to influenza infection reach and persist at higher numbers than CD4+ T cells independently of precursor frequency. Clin Immunol. 2004 Oct; 113(1):89-100.
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    Score: 0.004
  159. Dutton RW, Wetzel GD, Swain SL. Partial purification and characterization of a BCGFII from EL4 culture supernatants. J Immunol. 1984 May; 132(5):2451-6.
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    Score: 0.004
  160. Swain SL, Dialynas DP, Fitch FW, English M. Monoclonal antibody to L3T4 blocks the function of T cells specific for class 2 major histocompatibility complex antigens. J Immunol. 1984 Mar; 132(3):1118-23.
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    Score: 0.004
  161. Kagnoff MF, Arner LS, Swain SL. Lymphokine-mediated activation of a T cell-dependent IgA antipolysaccharide response. J Immunol. 1983 Nov; 131(5):2210-4.
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    Score: 0.004
  162. Swain SL, Howard M, Kappler J, Marrack P, Watson J, Booth R, Wetzel GD, Dutton RW. Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med. 1983 Sep 01; 158(3):822-35.
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    Score: 0.004
  163. Rogerson BJ, Harris DP, Swain SL, Burgess DO. Germinal center B cells in Peyer's patches of aged mice exhibit a normal activation phenotype and highly mutated IgM genes. Mech Ageing Dev. 2003 Feb; 124(2):155-65.
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    Score: 0.004
  164. Swain SL, Dutton RW, Schwab R, Yamamoto J. Xenogeneic human anti-mouse T cell responses are due to the activity of the same functional T cell subsets responsible for allospecific and major histocompatibility complex-restricted responses. J Exp Med. 1983 Feb 01; 157(2):720-9.
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    Score: 0.004
  165. Swain SL. T cell subsets and the recognition of MHC class. Immunol Rev. 1983; 74:129-42.
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    Score: 0.004
  166. Arnold PY, Vignali KM, Miller TB, La Gruta NL, Cauley LS, Haynes L, Scott Adams P, Swain SL, Woodland DL, Vignali DA. Reliable generation and use of MHC class II:gamma2aFc multimers for the identification of antigen-specific CD4(+) T cells. J Immunol Methods. 2002 Dec 20; 271(1-2):137-51.
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    Score: 0.004
  167. Swain SL, Dutton RW. Production of a B cell growth-promoting activity, (DL)BCGF, from a cloned T cell line and its assay on the BCL1 B cell tumor. J Exp Med. 1982 Dec 01; 156(6):1821-34.
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    Score: 0.004
  168. Lee BO, Haynes L, Eaton SM, Swain SL, Randall TD. The biological outcome of CD40 signaling is dependent on the duration of CD40 ligand expression: reciprocal regulation by interleukin (IL)-4 and IL-12. J Exp Med. 2002 Sep 02; 196(5):693-704.
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    Score: 0.004
  169. Dutton RW, Swain SL. Regulation of the immune response T-cell interactions. CRC Crit Rev Immunol. 1982 Feb; 3(3):209-61.
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    Score: 0.003
  170. Swain SL, Wetzel GD, Soubiran P, Dutton RW. T cell replacing factors in the B cell response to antigen. Immunol Rev. 1982; 63:111-28.
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    Score: 0.003
  171. Swain SL. Significance of Lyt phenotypes: Lyt2 antibodies block activities of T cells that recognize class 1 major histocompatibility complex antigens regardless of their function. Proc Natl Acad Sci U S A. 1981 Nov; 78(11):7101-5.
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    Score: 0.003
  172. Swain SL. Significance of class 1 and class 2 major histocompatibility complex antigens: help to allogeneic K and D antigens does not involve I recognition. J Immunol. 1981 Jun; 126(6):2307-9.
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    Score: 0.003
  173. Swain SL, Dennert G, Warner JF, Dutton RW. Culture supernatants of a stimulated T-cell line have helper activity that acts synergistically with interleukin 2 in the response of B cells to antigen. Proc Natl Acad Sci U S A. 1981 Apr; 78(4):2517-21.
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    Score: 0.003
  174. Swain SL, Dennert G, Wormsley S, Dutton RW. The Lyt phenotype of a long-term allospecific T cell line. Both helper and killer activities to IA are mediated by Ly-1 cells. Eur J Immunol. 1981 Mar; 11(3):175-80.
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    Score: 0.003
  175. Harris DP, Haynes L, Sayles PC, Duso DK, Eaton SM, Lepak NM, Johnson LL, Swain SL, Lund FE. Reciprocal regulation of polarized cytokine production by effector B and T cells. Nat Immunol. 2000 Dec; 1(6):475-82.
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    Score: 0.003
  176. Swain SL. Association of Ly phenotypes, T cell function and MHC recognition. Fed Proc. 1980 Nov; 39(13):3110-3.
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    Score: 0.003
  177. Mahnke K, Guo M, Lee S, Sepulveda H, Swain SL, Nussenzweig M, Steinman RM. The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J Cell Biol. 2000 Oct 30; 151(3):673-84.
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    Score: 0.003
  178. Swain SL. Role of Ia-positive cells in the production of T cell-replacing factors: blocking of factor production with anti-Ia serum. J Immunol. 1980 Sep; 125(3):1224-9.
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    Score: 0.003
  179. Dalton DK, Haynes L, Chu CQ, Swain SL, Wittmer S. Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells. J Exp Med. 2000 Jul 03; 192(1):117-22.
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    Score: 0.003
  180. Swain SL, Dutton RW. Production of Con A-induced helper T cell replacing factor requires a T cell and an Ia-positive non-T cells. J Immunol. 1980 Jan; 124(1):437-44.
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    Score: 0.003
  181. Swain SL, Bakke A, English M, Dutton RW. Ly phenotypes and MHC recognition: the allohelper that recognizes K or D is a mature Ly123 cell. J Immunol. 1979 Dec; 123(6):2716-24.
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    Score: 0.003
  182. Quong MW, Harris DP, Swain SL, Murre C. E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination. EMBO J. 1999 Nov 15; 18(22):6307-18.
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    Score: 0.003
  183. Swain SL, Panfili PR, Dutton RW, Lefkovits I. Frequency of allogeneic helper T cells responding to whole H-2 differences and to an H-2K difference alone. J Immunol. 1979 Sep; 123(3):1062-7.
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    Score: 0.003
  184. Dutton RW, Swain SL, Bradley LM. The generation and maintenance of memory T and B cells. Immunol Today. 1999 Jul; 20(7):291-3.
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    Score: 0.003
  185. Swain SL, Panfili PR. Helper cells activated by allogeneic H-2K or H-2D differences have a Ly phenotype distinct from those responsive to I differences. J Immunol. 1979 Feb; 122(2):383-91.
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    Score: 0.003
  186. Swain SL. Mechanism of allosuppression: evidence for direct suppression of responding B cells. J Immunol. 1978 Aug; 121(2):671-7.
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    Score: 0.003
  187. Cerwenka A, Carter LL, Reome JB, Swain SL, Dutton RW. In vivo persistence of CD8 polarized T cell subsets producing type 1 or type 2 cytokines. J Immunol. 1998 Jul 01; 161(1):97-105.
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    Score: 0.003
  188. Yasui DH, Genetta T, Kadesch T, Williams TM, Swain SL, Tsui LV, Huber BT. Transcriptional repression of the IL-2 gene in Th cells by ZEB. J Immunol. 1998 May 01; 160(9):4433-40.
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    Score: 0.003
  189. Dutton RW, Panfili PR, Swain SL. Alloreactivity, the development of the T cell repertoire and the understanding of T cell function. Immunol Rev. 1978; 42:20-59.
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    Score: 0.003
  190. Swain SL, Dutton RW. Negative allogeneic effects in vitro. II. Mapping of histocompatibility differences leading to allosuppression. J Immunol. 1977 Sep; 119(3):1179-86.
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    Score: 0.003
  191. Andrews C, Swain SL, Muralidhar G. CD4 T cell anergy in murine AIDS: costimulation via CD28 and the addition of IL-12 are not sufficient to rescue anergic CD4 T cells. J Immunol. 1997 Sep 01; 159(5):2132-8.
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    Score: 0.003
  192. Swain SL, Dutton RW. Negative allogeneic effects in vitro. I. Allogeneic T cells markedly suppress the secondary antibody-forming cell response. J Immunol. 1977 Jun; 118(6):2262-8.
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    Score: 0.003
  193. Swain SL, Trefts PE, Tse HY, Dutton RW. The significance of T-B collaboration across haplotype barriers. Cold Spring Harb Symp Quant Biol. 1977; 41 Pt 2:597-609.
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    Score: 0.002
  194. Raz E, Tighe H, Sato Y, Corr M, Dudler JA, Roman M, Swain SL, Spiegelberg HL, Carson DA. Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization. Proc Natl Acad Sci U S A. 1996 May 14; 93(10):5141-5.
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    Score: 0.002
  195. Yoshimoto K, Swain SL, Bradley LM. Enhanced development of Th2-like primary CD4 effectors in response to sustained exposure to limited rIL-4 in vivo. J Immunol. 1996 May 01; 156(9):3267-74.
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    Score: 0.002
  196. Jaiswal AI, Dubey C, Swain SL, Croft M. Regulation of CD40 ligand expression on naive CD4 T cells: a role for TCR but not co-stimulatory signals. Int Immunol. 1996 Feb; 8(2):275-85.
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    Score: 0.002
  197. Croft M, Carter L, Swain SL, Dutton RW. Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles. J Exp Med. 1994 Nov 01; 180(5):1715-28.
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    Score: 0.002
  198. Weinberg AD, Whitham R, Swain SL, Morrison WJ, Wyrick G, Hoy C, Vandenbark AA, Offner H. Transforming growth factor-beta enhances the in vivo effector function and memory phenotype of antigen-specific T helper cells in experimental autoimmune encephalomyelitis. J Immunol. 1992 Apr 01; 148(7):2109-17.
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    Score: 0.002
  199. Southern SO, Swain SL, Dutton RW. Induction of the H-2 D antigen during B cell activation. J Immunol. 1989 Jan 01; 142(1):336-42.
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    Score: 0.001
  200. Pfeifer JD, McKenzie DT, Swain SL, Dutton RW. B cell stimulatory factor 1 (interleukin 4) is sufficient for the proliferation and differentiation of lectin-stimulated cytolytic T lymphocyte precursors. J Exp Med. 1987 Nov 01; 166(5):1464-70.
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    Score: 0.001
  201. McKenzie DT, Filutowicz HI, Swain SL, Dutton RW. Purification and partial sequence analysis of murine B cell growth factor II (interleukin 5). J Immunol. 1987 Oct 15; 139(8):2661-8.
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    Score: 0.001
  202. Murray PD, McKenzie DT, Swain SL, Kagnoff MF. Interleukin 5 and interleukin 4 produced by Peyer's patch T cells selectively enhance immunoglobulin A expression. J Immunol. 1987 Oct 15; 139(8):2669-74.
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    Score: 0.001
  203. Kupfer A, Swain SL, Singer SJ. The specific direct interaction of helper T cells and antigen-presenting B cells. II. Reorientation of the microtubule organizing center and reorganization of the membrane-associated cytoskeleton inside the bound helper T cells. J Exp Med. 1987 Jun 01; 165(6):1565-80.
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    Score: 0.001
  204. Southern SO, Swain SL, Dutton RW. B cell surface glycoprotein induced during growth response: molecular structure and expression pattern. J Immunol. 1987 Apr 15; 138(8):2568-75.
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    Score: 0.001
  205. Kupfer A, Swain SL, Janeway CA, Singer SJ. The specific direct interaction of helper T cells and antigen-presenting B cells. Proc Natl Acad Sci U S A. 1986 Aug; 83(16):6080-3.
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    Score: 0.001
  206. Murray PD, Swain SL, Kagnoff MP. Regulation of the IgM and IgA anti-dextran B1355S response: synergy between IFN-gamma, BCGF II, and IL 2. J Immunol. 1985 Dec; 135(6):4015-20.
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    Score: 0.001
  207. Wetzel GD, Swain SL, Dutton RW, Kettman JR. Evidence for two distinct activation states available to B lymphocytes. J Immunol. 1984 Nov; 133(5):2327-32.
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    Score: 0.001
  208. Zimmerman B, Swain SL, Dutton RW. Immunosuppressive ATS. V. Analysis of the effect of anti-thymocyte serum on T lymphocyte subsets. J Immunol. 1982 Aug; 129(2):515-20.
    View in: PubMed
    Score: 0.001
  209. Wetzel GD, Swain SL, Dutton RW. A monoclonal T cell-replacing activity can act directly on B cells to enhance clonal expansion. J Exp Med. 1982 Jul 01; 156(1):306-11.
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    Score: 0.001
  210. Pur? E, Isakson PC, Takatsu K, Hamaoka T, Swain SL, Dutton RW, Dennert G, Uhr JW, Vitetta ES. Induction of B cell differentiation by T cell factors. I. Stimulation of IgM secretion by products of a T cell hybridoma and a T cell line. J Immunol. 1981 Nov; 127(5):1953-8.
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    Score: 0.001
  211. Dennert G, Swain SL, Waterfield JD, Warner JF, Dutton RW. Fine specificity mapping of two allospecific T cell lines: recognition of private specificities in the H-2 IA subregion. Eur J Immunol. 1981 Jan; 11(1):62-4.
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    Score: 0.001
  212. Shih WW, Matzinger PC, Swain SL, Dutton RW. Analysis of histocompatibility requirements for proliferative and helper T cell activity. T cell populations depleted of alloreactive cells by negative selection. J Exp Med. 1980 Nov 01; 152(5):1311-28.
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    Score: 0.001
  213. Waterfield JD, Dennert G, Swain SL, Dutton RW. Continuously proliferating allospecific T cells. I. Specificity of cooperation with allogeneic B cells in the humoral antibody response to sheep erythrocytes. J Exp Med. 1979 Apr 01; 149(4):808-14.
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    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.