Susan Swain to Interleukin-2
This is a "connection" page, showing publications Susan Swain has written about Interleukin-2.
Connection Strength
4.031
-
Jones MC, Castonguay C, Nanaware PP, Weaver GC, Stadinski B, Kugler-Umana OA, Huseby ES, Stern LJ, McKinstry KK, Strutt TM, Devarajan P, Swain SL. CD4 Effector TCR Avidity for Peptide on APC Determines the Level of Memory Generated. J Immunol. 2023 06 15; 210(12):1950-1961.
Score: 0.840
-
McKinstry KK, Strutt TM, Bautista B, Zhang W, Kuang Y, Cooper AM, Swain SL. Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2. Nat Commun. 2014 Nov 05; 5:5377.
Score: 0.463
-
Brown DM, Kamperschroer C, Dilzer AM, Roberts DM, Swain SL. IL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells. Cell Immunol. 2009; 257(1-2):69-79.
Score: 0.314
-
Alam F, Singh A, Flores-Malavet V, Sell S, Cooper AM, Swain SL, McKinstry KK, Strutt TM. CD25-Targeted IL-2 Signals Promote Improved Outcomes of Influenza Infection and Boost Memory CD4 T Cell Formation. J Immunol. 2020 06 15; 204(12):3307-3314.
Score: 0.169
-
Haynes L, Eaton SM, Swain SL. The defects in effector generation associated with aging can be reversed by addition of IL-2 but not other related gamma(c)-receptor binding cytokines. Vaccine. 2000 Feb 25; 18(16):1649-53.
Score: 0.167
-
Haynes L, Linton PJ, Eaton SM, Tonkonogy SL, Swain SL. Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice. J Exp Med. 1999 Oct 04; 190(7):1013-24.
Score: 0.163
-
McKinstry KK, Alam F, Flores-Malavet V, Nagy MZ, Sell S, Cooper AM, Swain SL, Strutt TM. Memory CD4 T cell-derived IL-2 synergizes with viral infection to exacerbate lung inflammation. PLoS Pathog. 2019 08; 15(8):e1007989.
Score: 0.161
-
Zhou X, Hopkins JW, Wang C, Brahmakshatriya V, Swain SL, Kuchel GA, Haynes L, McElhaney JE. IL-2 and IL-6 cooperate to enhance the generation of influenza-specific CD8 T cells responding to live influenza virus in aged mice and humans. Oncotarget. 2016 Jun 28; 7(26):39171-39183.
Score: 0.130
-
Zhang X, Giangreco L, Broome HE, Dargan CM, Swain SL. Control of CD4 effector fate: transforming growth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion. J Exp Med. 1995 Sep 01; 182(3):699-709.
Score: 0.122
-
Strutt TM, McKinstry KK, Kuang Y, Bradley LM, Swain SL. Memory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectors. Proc Natl Acad Sci U S A. 2012 Sep 18; 109(38):E2551-60.
Score: 0.099
-
Bradley LM, Duncan DD, Tonkonogy S, Swain SL. Characterization of antigen-specific CD4+ effector T cells in vivo: immunization results in a transient population of MEL-14-, CD45RB- helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon gamma. J Exp Med. 1991 Sep 01; 174(3):547-59.
Score: 0.093
-
Croft M, Swain SL. B cell response to fresh and effector T helper cells. Role of cognate T-B interaction and the cytokines IL-2, IL-4, and IL-6. J Immunol. 1991 Jun 15; 146(12):4055-64.
Score: 0.091
-
Swain SL. Lymphokines and the immune response: the central role of interleukin-2. Curr Opin Immunol. 1991 Jun; 3(3):304-10.
Score: 0.091
-
McKinstry KK, Strutt TM, Swain SL. Regulation of CD4+ T-cell contraction during pathogen challenge. Immunol Rev. 2010 Jul; 236:110-24.
Score: 0.086
-
Swain SL, McKenzie DT, Weinberg AD, Hancock W. Characterization of T helper 1 and 2 cell subsets in normal mice. Helper T cells responsible for IL-4 and IL-5 production are present as precursors that require priming before they develop into lymphokine-secreting cells. J Immunol. 1988 Nov 15; 141(10):3445-55.
Score: 0.076
-
Dienz O, Eaton SM, Krahl TJ, Diehl S, Charland C, Dodge J, Swain SL, Budd RC, Haynes L, Rincon M. Accumulation of NFAT mediates IL-2 expression in memory, but not na?ve, CD4+ T cells. Proc Natl Acad Sci U S A. 2007 Apr 24; 104(17):7175-80.
Score: 0.069
-
Clise-Dwyer K, Huston GE, Buck AL, Duso DK, Swain SL. Environmental and intrinsic factors lead to antigen unresponsiveness in CD4(+) recent thymic emigrants from aged mice. J Immunol. 2007 Feb 01; 178(3):1321-31.
Score: 0.068
-
Haynes L, Eaton SM, Burns EM, Randall TD, Swain SL. Newly generated CD4 T cells in aged animals do not exhibit age-related defects in response to antigen. J Exp Med. 2005 Mar 21; 201(6):845-51.
Score: 0.059
-
Haynes L, Eaton SM, Burns EM, Rincon M, Swain SL. Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo. J Immunol. 2004 May 01; 172(9):5194-9.
Score: 0.056
-
Haynes L, Eaton SM, Burns EM, Randall TD, Swain SL. CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):15053-8.
Score: 0.054
-
Haynes L, Eaton SM, Swain SL. Effect of age on naive CD4 responses: impact on effector generation and memory development. Springer Semin Immunopathol. 2002; 24(1):53-60.
Score: 0.047
-
Swain SL, Dennert G, Warner JF, Dutton RW. Culture supernatants of a stimulated T-cell line have helper activity that acts synergistically with interleukin 2 in the response of B cells to antigen. Proc Natl Acad Sci U S A. 1981 Apr; 78(4):2517-21.
Score: 0.045
-
Yasui DH, Genetta T, Kadesch T, Williams TM, Swain SL, Tsui LV, Huber BT. Transcriptional repression of the IL-2 gene in Th cells by ZEB. J Immunol. 1998 May 01; 160(9):4433-40.
Score: 0.037
-
Strutt TM, Dhume K, Finn CM, Hwang JH, Castonguay C, Swain SL, McKinstry KK. IL-15 supports the generation of protective lung-resident memory CD4 T cells. Mucosal Immunol. 2018 05; 11(3):668-680.
Score: 0.036
-
Dubey C, Croft M, Swain SL. Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals. J Immunol. 1996 Oct 15; 157(8):3280-9.
Score: 0.033
-
Muralidhar G, Koch S, Broome HE, Swain SL. TCR triggering of anergic CD4 T cells in murine AIDS induces apoptosis rather than cytokine synthesis and proliferation. J Immunol. 1996 Jul 15; 157(2):625-35.
Score: 0.033
-
Tinoco R, Carrette F, Barraza ML, Otero DC, Maga?a J, Bosenberg MW, Swain SL, Bradley LM. PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion. Immunity. 2016 05 17; 44(5):1190-203.
Score: 0.032
-
Dubey C, Croft M, Swain SL. Costimulatory requirements of naive CD4+ T cells. ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response. J Immunol. 1995 Jul 01; 155(1):45-57.
Score: 0.030
-
Croft M, Bradley LM, Swain SL. Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells. J Immunol. 1994 Mar 15; 152(6):2675-85.
Score: 0.028
-
Bradley LM, Duncan DD, Yoshimoto K, Swain SL. Memory effectors: a potent, IL-4-secreting helper T cell population that develops in vivo after restimulation with antigen. J Immunol. 1993 Apr 15; 150(8 Pt 1):3119-30.
Score: 0.026
-
Croft M, Duncan DD, Swain SL. Response of naive antigen-specific CD4+ T cells in vitro: characteristics and antigen-presenting cell requirements. J Exp Med. 1992 Nov 01; 176(5):1431-7.
Score: 0.025
-
Bradley LM, Atkins GG, Swain SL. Long-term CD4+ memory T cells from the spleen lack MEL-14, the lymph node homing receptor. J Immunol. 1992 Jan 15; 148(2):324-31.
Score: 0.024
-
Croft M, Swain SL. B cell response to T helper cell subsets. II. Both the stage of T cell differentiation and the cytokines secreted determine the extent and nature of helper activity. J Immunol. 1991 Dec 01; 147(11):3679-89.
Score: 0.024
-
Kubota E, McKenzie DT, Dutton RW, Swain SL. Role of T cells in the B-cell response: glutaraldehyde-fixed T-helper hybridoma cells synergize with the lymphokine IL-4 to induce B-cell activation and proliferation. Immunology. 1991 Jan; 72(1):40-7.
Score: 0.022
-
Swain SL, Weinberg AD, English M, Huston G. IL-4 directs the development of Th2-like helper effectors. J Immunol. 1990 Dec 01; 145(11):3796-806.
Score: 0.022
-
Swain SL, Weinberg AD, English M. CD4+ T cell subsets. Lymphokine secretion of memory cells and of effector cells that develop from precursors in vitro. J Immunol. 1990 Mar 01; 144(5):1788-99.
Score: 0.021
-
Maue AC, Yager EJ, Swain SL, Woodland DL, Blackman MA, Haynes L. T-cell immunosenescence: lessons learned from mouse models of aging. Trends Immunol. 2009 Jul; 30(7):301-5.
Score: 0.020
-
Swain SL, McKenzie DT, Dutton RW, Tonkonogy SL, English M. The role of IL4 and IL5: characterization of a distinct helper T cell subset that makes IL4 and IL5 (Th2) and requires priming before induction of lymphokine secretion. Immunol Rev. 1988 Feb; 102:77-105.
Score: 0.018
-
Murray PD, Swain SL, Kagnoff MP. Regulation of the IgM and IgA anti-dextran B1355S response: synergy between IFN-gamma, BCGF II, and IL 2. J Immunol. 1985 Dec; 135(6):4015-20.
Score: 0.016
-
Swain SL. Role of BCGFII in the differentiation to antibody secretion normal and tumor B cells. J Immunol. 1985 Jun; 134(6):3934-43.
Score: 0.015
-
Swain SL, Dialynas DP, Fitch FW, English M. Monoclonal antibody to L3T4 blocks the function of T cells specific for class 2 major histocompatibility complex antigens. J Immunol. 1984 Mar; 132(3):1118-23.
Score: 0.014
-
Kagnoff MF, Arner LS, Swain SL. Lymphokine-mediated activation of a T cell-dependent IgA antipolysaccharide response. J Immunol. 1983 Nov; 131(5):2210-4.
Score: 0.013
-
Swain SL, Dutton RW, Schwab R, Yamamoto J. Xenogeneic human anti-mouse T cell responses are due to the activity of the same functional T cell subsets responsible for allospecific and major histocompatibility complex-restricted responses. J Exp Med. 1983 Feb 01; 157(2):720-9.
Score: 0.013
-
Dutton RW, Swain SL. Regulation of the immune response T-cell interactions. CRC Crit Rev Immunol. 1982 Feb; 3(3):209-61.
Score: 0.012
-
Swain SL, Wetzel GD, Soubiran P, Dutton RW. T cell replacing factors in the B cell response to antigen. Immunol Rev. 1982; 63:111-28.
Score: 0.012
-
Pur? E, Isakson PC, Takatsu K, Hamaoka T, Swain SL, Dutton RW, Dennert G, Uhr JW, Vitetta ES. Induction of B cell differentiation by T cell factors. I. Stimulation of IgM secretion by products of a T cell hybridoma and a T cell line. J Immunol. 1981 Nov; 127(5):1953-8.
Score: 0.012
-
Andrews C, Swain SL, Muralidhar G. CD4 T cell anergy in murine AIDS: costimulation via CD28 and the addition of IL-12 are not sufficient to rescue anergic CD4 T cells. J Immunol. 1997 Sep 01; 159(5):2132-8.
Score: 0.009
-
Jaiswal AI, Dubey C, Swain SL, Croft M. Regulation of CD40 ligand expression on naive CD4 T cells: a role for TCR but not co-stimulatory signals. Int Immunol. 1996 Feb; 8(2):275-85.
Score: 0.008
-
Croft M, Carter L, Swain SL, Dutton RW. Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles. J Exp Med. 1994 Nov 01; 180(5):1715-28.
Score: 0.007
-
Pfeifer JD, McKenzie DT, Swain SL, Dutton RW. B cell stimulatory factor 1 (interleukin 4) is sufficient for the proliferation and differentiation of lectin-stimulated cytolytic T lymphocyte precursors. J Exp Med. 1987 Nov 01; 166(5):1464-70.
Score: 0.004
-
Zimmerman B, Swain SL, Dutton RW. Immunosuppressive ATS. V. Analysis of the effect of anti-thymocyte serum on T lymphocyte subsets. J Immunol. 1982 Aug; 129(2):515-20.
Score: 0.003