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Connection

Susan Swain to Lymphocyte Activation

This is a "connection" page, showing publications Susan Swain has written about Lymphocyte Activation.
Connection Strength

4.184
  1. Brahmakshatriya V, Kuang Y, Devarajan P, Xia J, Zhang W, Vong AM, Swain SL. IL-6 Production by TLR-Activated APC Broadly Enhances Aged Cognate CD4 Helper and B Cell Antibody Responses In Vivo. J Immunol. 2017 04 01; 198(7):2819-2833.
    View in: PubMed
    Score: 0.465
  2. Strutt TM, McKinstry KK, Swain SL. Control of innate immunity by memory CD4 T cells. Adv Exp Med Biol. 2011; 780:57-68.
    View in: PubMed
    Score: 0.303
  3. McKinstry KK, Strutt TM, Swain SL. Regulation of CD4+ T-cell contraction during pathogen challenge. Immunol Rev. 2010 Jul; 236:110-24.
    View in: PubMed
    Score: 0.293
  4. Agrewala JN, Brown DM, Lepak NM, Duso D, Huston G, Swain SL. Unique ability of activated CD4+ T cells but not rested effectors to migrate to non-lymphoid sites in the absence of inflammation. J Biol Chem. 2007 Mar 02; 282(9):6106-15.
    View in: PubMed
    Score: 0.230
  5. Yen MH, Lepak N, Swain SL. Induction of CD4 T cell changes in murine AIDS is dependent on costimulation and involves a dysregulation of homeostasis. J Immunol. 2002 Jul 15; 169(2):722-31.
    View in: PubMed
    Score: 0.169
  6. Rogers PR, Dubey C, Swain SL. Qualitative changes accompany memory T cell generation: faster, more effective responses at lower doses of antigen. J Immunol. 2000 Mar 01; 164(5):2338-46.
    View in: PubMed
    Score: 0.143
  7. Carter LL, Swain SL. From naive to memory. Development and regulation of CD4+ T cell responses. Immunol Res. 1998 Aug; 18(1):1-13.
    View in: PubMed
    Score: 0.128
  8. Zhang X, Brunner T, Carter L, Dutton RW, Rogers P, Bradley L, Sato T, Reed JC, Green D, Swain SL. Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/FasL-mediated apoptosis. J Exp Med. 1997 May 19; 185(10):1837-49.
    View in: PubMed
    Score: 0.118
  9. Muralidhar G, Koch S, Broome HE, Swain SL. TCR triggering of anergic CD4 T cells in murine AIDS induces apoptosis rather than cytokine synthesis and proliferation. J Immunol. 1996 Jul 15; 157(2):625-35.
    View in: PubMed
    Score: 0.111
  10. Swain SL, Croft M, Dubey C, Haynes L, Rogers P, Zhang X, Bradley LM. From naive to memory T cells. Immunol Rev. 1996 Apr; 150:143-67.
    View in: PubMed
    Score: 0.109
  11. Bradley LM, Duncan DD, Yoshimoto K, Swain SL. Memory effectors: a potent, IL-4-secreting helper T cell population that develops in vivo after restimulation with antigen. J Immunol. 1993 Apr 15; 150(8 Pt 1):3119-30.
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    Score: 0.089
  12. Kubota E, McKenzie DT, Dutton RW, Swain SL. Role of T cells in the B-cell response: glutaraldehyde-fixed T-helper hybridoma cells synergize with the lymphokine IL-4 to induce B-cell activation and proliferation. Immunology. 1991 Jan; 72(1):40-7.
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    Score: 0.076
  13. McKinstry KK, Strutt TM, Swain SL. The potential of CD4 T-cell memory. Immunology. 2010 May; 130(1):1-9.
    View in: PubMed
    Score: 0.072
  14. Tonkonogy SL, McKenzie DT, Swain SL. Regulation of isotype production by IL-4 and IL-5. Effects of lymphokines on Ig production depend on the state of activation of the responding B cells. J Immunol. 1989 Jun 15; 142(12):4351-60.
    View in: PubMed
    Score: 0.068
  15. Swain SL, McKenzie DT, Weinberg AD, Hancock W. Characterization of T helper 1 and 2 cell subsets in normal mice. Helper T cells responsible for IL-4 and IL-5 production are present as precursors that require priming before they develop into lymphokine-secreting cells. J Immunol. 1988 Nov 15; 141(10):3445-55.
    View in: PubMed
    Score: 0.065
  16. Swain SL, Dutton RW, McKenzie D, Helstrom H, English M. Role of antigen in the B cell response. Specific antigen and the lymphokine IL-5 synergize to drive B cell lymphoma proliferation and differentiation to Ig secretion. J Immunol. 1988 Jun 15; 140(12):4224-30.
    View in: PubMed
    Score: 0.064
  17. Hinshaw-Makepeace J, Huston G, Fortner KA, Russell JQ, Holoch D, Swain S, Budd RC. c-FLIP(S) reduces activation of caspase and NF-kappaB pathways and decreases T cell survival. Eur J Immunol. 2008 Jan; 38(1):54-63.
    View in: PubMed
    Score: 0.062
  18. McKinstry KK, Strutt TM, Swain SL. The effector to memory transition of CD4 T cells. Immunol Res. 2008; 40(2):114-27.
    View in: PubMed
    Score: 0.062
  19. Jelley-Gibbs DM, Dibble JP, Brown DM, Strutt TM, McKinstry KK, Swain SL. Persistent depots of influenza antigen fail to induce a cytotoxic CD8 T cell response. J Immunol. 2007 Jun 15; 178(12):7563-70.
    View in: PubMed
    Score: 0.059
  20. Clise-Dwyer K, Huston GE, Buck AL, Duso DK, Swain SL. Environmental and intrinsic factors lead to antigen unresponsiveness in CD4(+) recent thymic emigrants from aged mice. J Immunol. 2007 Feb 01; 178(3):1321-31.
    View in: PubMed
    Score: 0.058
  21. Swain SL, Dutton RW. B cell growth factor interactions. Adv Exp Med Biol. 1987; 213:215-25.
    View in: PubMed
    Score: 0.057
  22. Khader SA, Partida-Sanchez S, Bell G, Jelley-Gibbs DM, Swain S, Pearl JE, Ghilardi N, Desauvage FJ, Lund FE, Cooper AM. Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection. J Exp Med. 2006 Jul 10; 203(7):1805-15.
    View in: PubMed
    Score: 0.056
  23. Swain SL. Role of BCGFII in the differentiation to antibody secretion normal and tumor B cells. J Immunol. 1985 Jun; 134(6):3934-43.
    View in: PubMed
    Score: 0.051
  24. Kagnoff MF, Arner LS, Swain SL. Lymphokine-mediated activation of a T cell-dependent IgA antipolysaccharide response. J Immunol. 1983 Nov; 131(5):2210-4.
    View in: PubMed
    Score: 0.046
  25. Swain SL, Howard M, Kappler J, Marrack P, Watson J, Booth R, Wetzel GD, Dutton RW. Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med. 1983 Sep 01; 158(3):822-35.
    View in: PubMed
    Score: 0.046
  26. Rom?n E, Miller E, Harmsen A, Wiley J, Von Andrian UH, Huston G, Swain SL. CD4 effector T cell subsets in the response to influenza: heterogeneity, migration, and function. J Exp Med. 2002 Oct 07; 196(7):957-68.
    View in: PubMed
    Score: 0.043
  27. Haynes L, Eaton SM, Swain SL. Effect of age on naive CD4 responses: impact on effector generation and memory development. Springer Semin Immunopathol. 2002; 24(1):53-60.
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    Score: 0.041
  28. Swain SL, Dutton RW. The role of IA in G-cell activation. Transplant Proc. 1981 Dec; 13(4):1843-5.
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    Score: 0.040
  29. Harris DP, Koch S, Mullen LM, Swain SL. B cell immunodeficiency fails to develop in CD4-deficient mice infected with BM5: murine AIDS as a multistep disease. J Immunol. 2001 May 15; 166(10):6041-9.
    View in: PubMed
    Score: 0.039
  30. Cauley LS, Miller EE, Yen M, Swain SL. Superantigen-induced CD4 T cell tolerance mediated by myeloid cells and IFN-gamma. J Immunol. 2000 Dec 01; 165(11):6056-66.
    View in: PubMed
    Score: 0.038
  31. Haynes L, Eaton SM, Swain SL. The defects in effector generation associated with aging can be reversed by addition of IL-2 but not other related gamma(c)-receptor binding cytokines. Vaccine. 2000 Feb 25; 18(16):1649-53.
    View in: PubMed
    Score: 0.036
  32. Haynes L, Linton PJ, Eaton SM, Tonkonogy SL, Swain SL. Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice. J Exp Med. 1999 Oct 04; 190(7):1013-24.
    View in: PubMed
    Score: 0.035
  33. Swain SL. Helper T cell differentiation. Curr Opin Immunol. 1999 Apr; 11(2):180-5.
    View in: PubMed
    Score: 0.034
  34. Rogers PR, Huston G, Swain SL. High antigen density and IL-2 are required for generation of CD4 effectors secreting Th1 rather than Th0 cytokines. J Immunol. 1998 Oct 15; 161(8):3844-52.
    View in: PubMed
    Score: 0.033
  35. Strutt TM, Dhume K, Finn CM, Hwang JH, Castonguay C, Swain SL, McKinstry KK. IL-15 supports the generation of protective lung-resident memory CD4 T cells. Mucosal Immunol. 2018 05; 11(3):668-680.
    View in: PubMed
    Score: 0.031
  36. Linton PJ, Haynes L, Klinman NR, Swain SL. Antigen-independent changes in naive CD4 T cells with aging. J Exp Med. 1996 Nov 01; 184(5):1891-900.
    View in: PubMed
    Score: 0.028
  37. Dubey C, Croft M, Swain SL. Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals. J Immunol. 1996 Oct 15; 157(8):3280-9.
    View in: PubMed
    Score: 0.028
  38. Tinoco R, Carrette F, Barraza ML, Otero DC, Maga?a J, Bosenberg MW, Swain SL, Bradley LM. PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion. Immunity. 2016 05 17; 44(5):1190-203.
    View in: PubMed
    Score: 0.028
  39. Yoshimoto K, Swain SL, Bradley LM. Enhanced development of Th2-like primary CD4 effectors in response to sustained exposure to limited rIL-4 in vivo. J Immunol. 1996 May 01; 156(9):3267-74.
    View in: PubMed
    Score: 0.027
  40. Jaiswal AI, Dubey C, Swain SL, Croft M. Regulation of CD40 ligand expression on naive CD4 T cells: a role for TCR but not co-stimulatory signals. Int Immunol. 1996 Feb; 8(2):275-85.
    View in: PubMed
    Score: 0.027
  41. Brodeur TY, Robidoux TE, Weinstein JS, Craft J, Swain SL, Marshak-Rothstein A. IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells. J Immunol. 2015 Dec 01; 195(11):5251-60.
    View in: PubMed
    Score: 0.026
  42. Zhang X, Giangreco L, Broome HE, Dargan CM, Swain SL. Control of CD4 effector fate: transforming growth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion. J Exp Med. 1995 Sep 01; 182(3):699-709.
    View in: PubMed
    Score: 0.026
  43. Dubey C, Croft M, Swain SL. Costimulatory requirements of naive CD4+ T cells. ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response. J Immunol. 1995 Jul 01; 155(1):45-57.
    View in: PubMed
    Score: 0.026
  44. Croft M, Swain SL. Recently activated naive CD4 T cells can help resting B cells, and can produce sufficient autocrine IL-4 to drive differentiation to secretion of T helper 2-type cytokines. J Immunol. 1995 May 01; 154(9):4269-82.
    View in: PubMed
    Score: 0.026
  45. Swain SL. CD4 T cell development and cytokine polarization: an overview. J Leukoc Biol. 1995 May; 57(5):795-8.
    View in: PubMed
    Score: 0.026
  46. Bradley LM, Watson SR, Swain SL. Entry of naive CD4 T cells into peripheral lymph nodes requires L-selectin. J Exp Med. 1994 Dec 01; 180(6):2401-6.
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    Score: 0.025
  47. Swain SL. Generation and in vivo persistence of polarized Th1 and Th2 memory cells. Immunity. 1994 Oct; 1(7):543-52.
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    Score: 0.025
  48. Duncan DD, Swain SL. Role of antigen-presenting cells in the polarized development of helper T cell subsets: evidence for differential cytokine production by Th0 cells in response to antigen presentation by B cells and macrophages. Eur J Immunol. 1994 Oct; 24(10):2506-14.
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    Score: 0.025
  49. Bradley LM, Croft M, Swain SL. T-cell memory: new perspectives. Immunol Today. 1993 May; 14(5):197-9.
    View in: PubMed
    Score: 0.022
  50. Croft M, Duncan DD, Swain SL. Response of naive antigen-specific CD4+ T cells in vitro: characteristics and antigen-presenting cell requirements. J Exp Med. 1992 Nov 01; 176(5):1431-7.
    View in: PubMed
    Score: 0.022
  51. Muralidhar G, Koch S, Haas M, Swain SL. CD4 T cells in murine acquired immunodeficiency syndrome: polyclonal progression to anergy. J Exp Med. 1992 Jun 01; 175(6):1589-99.
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    Score: 0.021
  52. Swain SL, Bradley LM. Helper T cell memory: more questions than answers. Semin Immunol. 1992 Feb; 4(1):59-68.
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    Score: 0.020
  53. Bradley LM, Atkins GG, Swain SL. Long-term CD4+ memory T cells from the spleen lack MEL-14, the lymph node homing receptor. J Immunol. 1992 Jan 15; 148(2):324-31.
    View in: PubMed
    Score: 0.020
  54. Croft M, Swain SL. B cell response to T helper cell subsets. II. Both the stage of T cell differentiation and the cytokines secreted determine the extent and nature of helper activity. J Immunol. 1991 Dec 01; 147(11):3679-89.
    View in: PubMed
    Score: 0.020
  55. Swain SL, Bradley LM, Croft M, Tonkonogy S, Atkins G, Weinberg AD, Duncan DD, Hedrick SM, Dutton RW, Huston G. Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development. Immunol Rev. 1991 Oct; 123:115-44.
    View in: PubMed
    Score: 0.020
  56. Croft M, Swain SL. B cell response to fresh and effector T helper cells. Role of cognate T-B interaction and the cytokines IL-2, IL-4, and IL-6. J Immunol. 1991 Jun 15; 146(12):4055-64.
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    Score: 0.020
  57. Swain SL, Dutton RW. Is autoimmunity good for you? The Molecular Basis of Recognition in the Immune System sponsored by the European Federation of Immunological Societies, Edinburgh, UK, September 10-12, 1990. New Biol. 1991 Feb; 3(2):117-20.
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    Score: 0.019
  58. Swain SL, Croft M. Critical role of cognate interactions in the response of small, high-density B cells. Res Immunol. 1990 May-Jun; 141(4-5):431-40.
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    Score: 0.018
  59. Weinberg AD, English M, Swain SL. Distinct regulation of lymphokine production is found in fresh versus in vitro primed murine helper T cells. J Immunol. 1990 Mar 01; 144(5):1800-7.
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    Score: 0.018
  60. Swain SL. Role of helper T cells in the B cell response. Contrib Microbiol Immunol. 1989; 11:43-72.
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    Score: 0.017
  61. Southern SO, Swain SL, Dutton RW. Induction of the H-2 D antigen during B cell activation. J Immunol. 1989 Jan 01; 142(1):336-42.
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    Score: 0.017
  62. Tonkonogy SL, Swain SL. Stimulation of gut-associated lymphoid cells by IL-4 and B-cell growth factor II. Immunology. 1988 May; 64(1):155-61.
    View in: PubMed
    Score: 0.016
  63. Li X, McKinstry KK, Swain SL, Dalton DK. IFN-gamma acts directly on activated CD4+ T cells during mycobacterial infection to promote apoptosis by inducing components of the intracellular apoptosis machinery and by inducing extracellular proapoptotic signals. J Immunol. 2007 Jul 15; 179(2):939-49.
    View in: PubMed
    Score: 0.015
  64. Kamperschroer C, Swain SL, Grussenmeyer T, Lefkovits I. SAP deficiency results in a striking alteration of the protein profile in activated CD4 T cells. J Proteome Res. 2006 Jul; 5(7):1785-91.
    View in: PubMed
    Score: 0.014
  65. Wetzel GD, Swain SL, Dutton RW, Kettman JR. Evidence for two distinct activation states available to B lymphocytes. J Immunol. 1984 Nov; 133(5):2327-32.
    View in: PubMed
    Score: 0.012
  66. Dutton RW, Wetzel GD, Swain SL. Partial purification and characterization of a BCGFII from EL4 culture supernatants. J Immunol. 1984 May; 132(5):2451-6.
    View in: PubMed
    Score: 0.012
  67. Swain SL, Dutton RW, Schwab R, Yamamoto J. Xenogeneic human anti-mouse T cell responses are due to the activity of the same functional T cell subsets responsible for allospecific and major histocompatibility complex-restricted responses. J Exp Med. 1983 Feb 01; 157(2):720-9.
    View in: PubMed
    Score: 0.011
  68. Swain SL. T cell subsets and the recognition of MHC class. Immunol Rev. 1983; 74:129-42.
    View in: PubMed
    Score: 0.011
  69. Swain SL, Dutton RW. Production of a B cell growth-promoting activity, (DL)BCGF, from a cloned T cell line and its assay on the BCL1 B cell tumor. J Exp Med. 1982 Dec 01; 156(6):1821-34.
    View in: PubMed
    Score: 0.011
  70. Lee BO, Haynes L, Eaton SM, Swain SL, Randall TD. The biological outcome of CD40 signaling is dependent on the duration of CD40 ligand expression: reciprocal regulation by interleukin (IL)-4 and IL-12. J Exp Med. 2002 Sep 02; 196(5):693-704.
    View in: PubMed
    Score: 0.011
  71. Wetzel GD, Swain SL, Dutton RW. A monoclonal T cell-replacing activity can act directly on B cells to enhance clonal expansion. J Exp Med. 1982 Jul 01; 156(1):306-11.
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    Score: 0.011
  72. Dutton RW, Swain SL. Regulation of the immune response T-cell interactions. CRC Crit Rev Immunol. 1982 Feb; 3(3):209-61.
    View in: PubMed
    Score: 0.010
  73. Swain SL, Wetzel GD, Soubiran P, Dutton RW. T cell replacing factors in the B cell response to antigen. Immunol Rev. 1982; 63:111-28.
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    Score: 0.010
  74. Swain SL. Association of Ly phenotypes, T cell function and MHC recognition. Fed Proc. 1980 Nov; 39(13):3110-3.
    View in: PubMed
    Score: 0.009
  75. Dalton DK, Haynes L, Chu CQ, Swain SL, Wittmer S. Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells. J Exp Med. 2000 Jul 03; 192(1):117-22.
    View in: PubMed
    Score: 0.009
  76. Quong MW, Harris DP, Swain SL, Murre C. E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination. EMBO J. 1999 Nov 15; 18(22):6307-18.
    View in: PubMed
    Score: 0.009
  77. Cerwenka A, Carter LL, Reome JB, Swain SL, Dutton RW. In vivo persistence of CD8 polarized T cell subsets producing type 1 or type 2 cytokines. J Immunol. 1998 Jul 01; 161(1):97-105.
    View in: PubMed
    Score: 0.008
  78. Dutton RW, Panfili PR, Swain SL. Alloreactivity, the development of the T cell repertoire and the understanding of T cell function. Immunol Rev. 1978; 42:20-59.
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    Score: 0.008
  79. Andrews C, Swain SL, Muralidhar G. CD4 T cell anergy in murine AIDS: costimulation via CD28 and the addition of IL-12 are not sufficient to rescue anergic CD4 T cells. J Immunol. 1997 Sep 01; 159(5):2132-8.
    View in: PubMed
    Score: 0.008
  80. Swain SL, Dutton RW. Negative allogeneic effects in vitro. I. Allogeneic T cells markedly suppress the secondary antibody-forming cell response. J Immunol. 1977 Jun; 118(6):2262-8.
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    Score: 0.007
  81. Swain SL, Trefts PE, Tse HY, Dutton RW. The significance of T-B collaboration across haplotype barriers. Cold Spring Harb Symp Quant Biol. 1977; 41 Pt 2:597-609.
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    Score: 0.007
  82. Murray PD, McKenzie DT, Swain SL, Kagnoff MF. Interleukin 5 and interleukin 4 produced by Peyer's patch T cells selectively enhance immunoglobulin A expression. J Immunol. 1987 Oct 15; 139(8):2669-74.
    View in: PubMed
    Score: 0.004
  83. Southern SO, Swain SL, Dutton RW. B cell surface glycoprotein induced during growth response: molecular structure and expression pattern. J Immunol. 1987 Apr 15; 138(8):2568-75.
    View in: PubMed
    Score: 0.004
  84. Murray PD, Swain SL, Kagnoff MP. Regulation of the IgM and IgA anti-dextran B1355S response: synergy between IFN-gamma, BCGF II, and IL 2. J Immunol. 1985 Dec; 135(6):4015-20.
    View in: PubMed
    Score: 0.003
  85. Pur? E, Isakson PC, Takatsu K, Hamaoka T, Swain SL, Dutton RW, Dennert G, Uhr JW, Vitetta ES. Induction of B cell differentiation by T cell factors. I. Stimulation of IgM secretion by products of a T cell hybridoma and a T cell line. J Immunol. 1981 Nov; 127(5):1953-8.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.