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Connection

Susan Swain to Immunologic Memory

This is a "connection" page, showing publications Susan Swain has written about Immunologic Memory.
Connection Strength

11.582
  1. Swain SL. CD4 memory has a hierarchical structure created by requirements for infection-derived signals at an effector checkpoint. Front Immunol. 2023; 14:1306433.
    View in: PubMed
    Score: 0.761
  2. Swain SL, Jones MC, Devarajan P, Xia J, Dutton RW, Strutt TM, McKinstry KK. Durable CD4 T-Cell Memory Generation Depends on Persistence of High Levels of Infection at an Effector Checkpoint that Determines Multiple Fates. Cold Spring Harb Perspect Biol. 2021 11 01; 13(11).
    View in: PubMed
    Score: 0.658
  3. Xia J, Kuang Y, Liang J, Jones M, Swain SL. Influenza Vaccine-Induced CD4 Effectors Require Antigen Recognition at an Effector Checkpoint to Generate CD4 Lung Memory and Antibody Production. J Immunol. 2020 10 15; 205(8):2077-2090.
    View in: PubMed
    Score: 0.608
  4. Devarajan P, Jones MC, Kugler-Umana O, Vong AM, Xia J, Swain SL. Pathogen Recognition by CD4 Effectors Drives Key Effector and Most Memory Cell Generation Against Respiratory Virus. Front Immunol. 2018; 9:596.
    View in: PubMed
    Score: 0.512
  5. Bautista BL, Devarajan P, McKinstry KK, Strutt TM, Vong AM, Jones MC, Kuang Y, Mott D, Swain SL. Short-Lived Antigen Recognition but Not Viral Infection at a Defined Checkpoint Programs Effector CD4 T Cells To Become Protective Memory. J Immunol. 2016 11 15; 197(10):3936-3949.
    View in: PubMed
    Score: 0.464
  6. McKinstry KK, Strutt TM, Bautista B, Zhang W, Kuang Y, Cooper AM, Swain SL. Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2. Nat Commun. 2014 Nov 05; 5:5377.
    View in: PubMed
    Score: 0.405
  7. Strutt TM, McKinstry KK, Marshall NB, Vong AM, Dutton RW, Swain SL. Multipronged CD4(+) T-cell effector and memory responses cooperate to provide potent immunity against respiratory virus. Immunol Rev. 2013 Sep; 255(1):149-64.
    View in: PubMed
    Score: 0.373
  8. Strutt TM, McKinstry KK, Kuang Y, Bradley LM, Swain SL. Memory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectors. Proc Natl Acad Sci U S A. 2012 Sep 18; 109(38):E2551-60.
    View in: PubMed
    Score: 0.348
  9. McKinstry KK, Strutt TM, Swain SL. Hallmarks of CD4 T cell immunity against influenza. J Intern Med. 2011 May; 269(5):507-18.
    View in: PubMed
    Score: 0.315
  10. Strutt TM, McKinstry KK, Swain SL. Control of innate immunity by memory CD4 T cells. Adv Exp Med Biol. 2011; 780:57-68.
    View in: PubMed
    Score: 0.310
  11. Strutt TM, McKinstry KK, Dibble JP, Winchell C, Kuang Y, Curtis JD, Huston G, Dutton RW, Swain SL. Memory CD4+ T cells induce innate responses independently of pathogen. Nat Med. 2010 May; 16(5):558-64, 1p following 564.
    View in: PubMed
    Score: 0.296
  12. McKinstry KK, Strutt TM, Swain SL. The potential of CD4 T-cell memory. Immunology. 2010 May; 130(1):1-9.
    View in: PubMed
    Score: 0.294
  13. Strutt TM, McKinstry KK, Swain SL. Functionally diverse subsets in CD4 T cell responses against influenza. J Clin Immunol. 2009 Mar; 29(2):145-50.
    View in: PubMed
    Score: 0.269
  14. Jelley-Gibbs DM, Strutt TM, McKinstry KK, Swain SL. Influencing the fates of CD4 T cells on the path to memory: lessons from influenza. Immunol Cell Biol. 2008 May-Jun; 86(4):343-52.
    View in: PubMed
    Score: 0.256
  15. McKinstry KK, Strutt TM, Swain SL. The effector to memory transition of CD4 T cells. Immunol Res. 2008; 40(2):114-27.
    View in: PubMed
    Score: 0.252
  16. McKinstry KK, Golech S, Lee WH, Huston G, Weng NP, Swain SL. Rapid default transition of CD4 T cell effectors to functional memory cells. J Exp Med. 2007 Sep 03; 204(9):2199-211.
    View in: PubMed
    Score: 0.246
  17. Swain SL, Agrewala JN, Brown DM, Jelley-Gibbs DM, Golech S, Huston G, Jones SC, Kamperschroer C, Lee WH, McKinstry KK, Rom?n E, Strutt T, Weng NP. CD4+ T-cell memory: generation and multi-faceted roles for CD4+ T cells in protective immunity to influenza. Immunol Rev. 2006 Jun; 211:8-22.
    View in: PubMed
    Score: 0.226
  18. Swain SL. Thanks for the memory! J Immunol. 2005 Oct 15; 175(8):4823-6.
    View in: PubMed
    Score: 0.216
  19. Jelley-Gibbs DM, Brown DM, Dibble JP, Haynes L, Eaton SM, Swain SL. Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation. J Exp Med. 2005 Sep 05; 202(5):697-706.
    View in: PubMed
    Score: 0.215
  20. Bradley LM, Haynes L, Swain SL. IL-7: maintaining T-cell memory and achieving homeostasis. Trends Immunol. 2005 Mar; 26(3):172-6.
    View in: PubMed
    Score: 0.207
  21. Swain SL, Dutton RW, Woodland DL. T cell responses to influenza virus infection: effector and memory cells. Viral Immunol. 2004; 17(2):197-209.
    View in: PubMed
    Score: 0.191
  22. Li J, Huston G, Swain SL. IL-7 promotes the transition of CD4 effectors to persistent memory cells. J Exp Med. 2003 Dec 15; 198(12):1807-15.
    View in: PubMed
    Score: 0.190
  23. Jones MC, Castonguay C, Nanaware PP, Weaver GC, Stadinski B, Kugler-Umana OA, Huseby ES, Stern LJ, McKinstry KK, Strutt TM, Devarajan P, Swain SL. CD4 Effector TCR Avidity for Peptide on APC Determines the Level of Memory Generated. J Immunol. 2023 06 15; 210(12):1950-1961.
    View in: PubMed
    Score: 0.184
  24. Swain SL. Regulation of the generation and maintenance of T-cell memory: a direct, default pathway from effectors to memory cells. Microbes Infect. 2003 Mar; 5(3):213-9.
    View in: PubMed
    Score: 0.180
  25. Haynes L, Eaton SM, Swain SL. Effect of age on naive CD4 responses: impact on effector generation and memory development. Springer Semin Immunopathol. 2002; 24(1):53-60.
    View in: PubMed
    Score: 0.166
  26. Swain SL, Agrewala JN, Brown DM, Rom?n E. Regulation of memory CD4 T cells: generation, localization and persistence. Adv Exp Med Biol. 2002; 512:113-20.
    View in: PubMed
    Score: 0.166
  27. Hu H, Huston G, Duso D, Lepak N, Roman E, Swain SL. CD4(+) T cell effectors can become memory cells with high efficiency and without further division. Nat Immunol. 2001 Aug; 2(8):705-10.
    View in: PubMed
    Score: 0.162
  28. Jelley-Gibbs DM, Lepak NM, Yen M, Swain SL. Two distinct stages in the transition from naive CD4 T cells to effectors, early antigen-dependent and late cytokine-driven expansion and differentiation. J Immunol. 2000 Nov 01; 165(9):5017-26.
    View in: PubMed
    Score: 0.153
  29. Alam F, Singh A, Flores-Malavet V, Sell S, Cooper AM, Swain SL, McKinstry KK, Strutt TM. CD25-Targeted IL-2 Signals Promote Improved Outcomes of Influenza Infection and Boost Memory CD4 T Cell Formation. J Immunol. 2020 06 15; 204(12):3307-3314.
    View in: PubMed
    Score: 0.148
  30. Swain SL. CD4 T-cell memory can persist in the absence of class II. Philos Trans R Soc Lond B Biol Sci. 2000 Mar 29; 355(1395):407-11.
    View in: PubMed
    Score: 0.147
  31. Rogers PR, Dubey C, Swain SL. Qualitative changes accompany memory T cell generation: faster, more effective responses at lower doses of antigen. J Immunol. 2000 Mar 01; 164(5):2338-46.
    View in: PubMed
    Score: 0.146
  32. Swain SL, Hu H, Huston G. Class II-independent generation of CD4 memory T cells from effectors. Science. 1999 Nov 12; 286(5443):1381-3.
    View in: PubMed
    Score: 0.143
  33. McKinstry KK, Alam F, Flores-Malavet V, Nagy MZ, Sell S, Cooper AM, Swain SL, Strutt TM. Memory CD4 T cell-derived IL-2 synergizes with viral infection to exacerbate lung inflammation. PLoS Pathog. 2019 08; 15(8):e1007989.
    View in: PubMed
    Score: 0.141
  34. Carter LL, Swain SL. From naive to memory. Development and regulation of CD4+ T cell responses. Immunol Res. 1998 Aug; 18(1):1-13.
    View in: PubMed
    Score: 0.131
  35. Carter LL, Zhang X, Dubey C, Rogers P, Tsui L, Swain SL. Regulation of T cell subsets from naive to memory. J Immunother. 1998 May; 21(3):181-7.
    View in: PubMed
    Score: 0.129
  36. Dutton RW, Bradley LM, Swain SL. T cell memory. Annu Rev Immunol. 1998; 16:201-23.
    View in: PubMed
    Score: 0.126
  37. Swain SL, Croft M, Dubey C, Haynes L, Rogers P, Zhang X, Bradley LM. From naive to memory T cells. Immunol Rev. 1996 Apr; 150:143-67.
    View in: PubMed
    Score: 0.112
  38. Bradley LM, Yoshimoto K, Swain SL. The cytokines IL-4, IFN-gamma, and IL-12 regulate the development of subsets of memory effector helper T cells in vitro. J Immunol. 1995 Aug 15; 155(4):1713-24.
    View in: PubMed
    Score: 0.107
  39. Swain SL. Generation and in vivo persistence of polarized Th1 and Th2 memory cells. Immunity. 1994 Oct; 1(7):543-52.
    View in: PubMed
    Score: 0.101
  40. Koch S, Muralidhar G, Swain SL. Both naive and memory CD4 T cell subsets become anergic during MAIDS and each subset can sustain disease. J Immunol. 1994 Jun 01; 152(11):5548-56.
    View in: PubMed
    Score: 0.098
  41. Croft M, Bradley LM, Swain SL. Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells. J Immunol. 1994 Mar 15; 152(6):2675-85.
    View in: PubMed
    Score: 0.097
  42. McKinstry KK, Dutton RW, Swain SL, Strutt TM. Memory CD4 T cell-mediated immunity against influenza A virus: more than a little helpful. Arch Immunol Ther Exp (Warsz). 2013 Oct; 61(5):341-53.
    View in: PubMed
    Score: 0.092
  43. Bradley LM, Croft M, Swain SL. T-cell memory: new perspectives. Immunol Today. 1993 May; 14(5):197-9.
    View in: PubMed
    Score: 0.091
  44. Bradley LM, Duncan DD, Yoshimoto K, Swain SL. Memory effectors: a potent, IL-4-secreting helper T cell population that develops in vivo after restimulation with antigen. J Immunol. 1993 Apr 15; 150(8 Pt 1):3119-30.
    View in: PubMed
    Score: 0.091
  45. McKinstry KK, Strutt TM, Kuang Y, Brown DM, Sell S, Dutton RW, Swain SL. Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms. J Clin Invest. 2012 Aug; 122(8):2847-56.
    View in: PubMed
    Score: 0.086
  46. Swain SL, Bradley LM. Helper T cell memory: more questions than answers. Semin Immunol. 1992 Feb; 4(1):59-68.
    View in: PubMed
    Score: 0.084
  47. Swain SL, McKinstry KK, Strutt TM. Expanding roles for CD4? T cells in immunity to viruses. Nat Rev Immunol. 2012 Jan 20; 12(2):136-48.
    View in: PubMed
    Score: 0.083
  48. Bradley LM, Atkins GG, Swain SL. Long-term CD4+ memory T cells from the spleen lack MEL-14, the lymph node homing receptor. J Immunol. 1992 Jan 15; 148(2):324-31.
    View in: PubMed
    Score: 0.083
  49. Swain SL, Weinberg AD, English M. CD4+ T cell subsets. Lymphokine secretion of memory cells and of effector cells that develop from precursors in vitro. J Immunol. 1990 Mar 01; 144(5):1788-99.
    View in: PubMed
    Score: 0.073
  50. Eaton SM, Maue AC, Swain SL, Haynes L. Bone marrow precursor cells from aged mice generate CD4 T cells that function well in primary and memory responses. J Immunol. 2008 Oct 01; 181(7):4825-31.
    View in: PubMed
    Score: 0.066
  51. Dienz O, Eaton SM, Krahl TJ, Diehl S, Charland C, Dodge J, Swain SL, Budd RC, Haynes L, Rincon M. Accumulation of NFAT mediates IL-2 expression in memory, but not na?ve, CD4+ T cells. Proc Natl Acad Sci U S A. 2007 Apr 24; 104(17):7175-80.
    View in: PubMed
    Score: 0.060
  52. Agrewala JN, Brown DM, Lepak NM, Duso D, Huston G, Swain SL. Unique ability of activated CD4+ T cells but not rested effectors to migrate to non-lymphoid sites in the absence of inflammation. J Biol Chem. 2007 Mar 02; 282(9):6106-15.
    View in: PubMed
    Score: 0.059
  53. Jelley-Gibbs DM, Dibble JP, Filipson S, Haynes L, Kemp RA, Swain SL. Repeated stimulation of CD4 effector T cells can limit their protective function. J Exp Med. 2005 Apr 04; 201(7):1101-12.
    View in: PubMed
    Score: 0.052
  54. Brown DM, Rom?n E, Swain SL. CD4 T cell responses to influenza infection. Semin Immunol. 2004 Jun; 16(3):171-7.
    View in: PubMed
    Score: 0.049
  55. Haynes L, Eaton SM, Burns EM, Randall TD, Swain SL. CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):15053-8.
    View in: PubMed
    Score: 0.047
  56. Haynes L, Eaton SM, Swain SL. The defects in effector generation associated with aging can be reversed by addition of IL-2 but not other related gamma(c)-receptor binding cytokines. Vaccine. 2000 Feb 25; 18(16):1649-53.
    View in: PubMed
    Score: 0.037
  57. Swain SL. Helper T cell differentiation. Curr Opin Immunol. 1999 Apr; 11(2):180-5.
    View in: PubMed
    Score: 0.034
  58. Strutt TM, Dhume K, Finn CM, Hwang JH, Castonguay C, Swain SL, McKinstry KK. IL-15 supports the generation of protective lung-resident memory CD4 T cells. Mucosal Immunol. 2018 05; 11(3):668-680.
    View in: PubMed
    Score: 0.031
  59. Haynes L, Linton PJ, Swain SL. Age-related changes in CD4 T cells of T cell receptor transgenic mice. Mech Ageing Dev. 1997 Feb; 93(1-3):95-105.
    View in: PubMed
    Score: 0.030
  60. Linton PJ, Haynes L, Klinman NR, Swain SL. Antigen-independent changes in naive CD4 T cells with aging. J Exp Med. 1996 Nov 01; 184(5):1891-900.
    View in: PubMed
    Score: 0.029
  61. Swain SL. CD4 T cell development and cytokine polarization: an overview. J Leukoc Biol. 1995 May; 57(5):795-8.
    View in: PubMed
    Score: 0.026
  62. Weinberg AD, Whitham R, Swain SL, Morrison WJ, Wyrick G, Hoy C, Vandenbark AA, Offner H. Transforming growth factor-beta enhances the in vivo effector function and memory phenotype of antigen-specific T helper cells in experimental autoimmune encephalomyelitis. J Immunol. 1992 Apr 01; 148(7):2109-17.
    View in: PubMed
    Score: 0.021
  63. Bradley LM, Duncan DD, Tonkonogy S, Swain SL. Characterization of antigen-specific CD4+ effector T cells in vivo: immunization results in a transient population of MEL-14-, CD45RB- helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon gamma. J Exp Med. 1991 Sep 01; 174(3):547-59.
    View in: PubMed
    Score: 0.020
  64. Swain SL. Regulation of the development of helper T cell subsets. Immunol Res. 1991; 10(3-4):177-82.
    View in: PubMed
    Score: 0.019
  65. Swain SL, Croft M. Critical role of cognate interactions in the response of small, high-density B cells. Res Immunol. 1990 May-Jun; 141(4-5):431-40.
    View in: PubMed
    Score: 0.019
  66. Maue AC, Yager EJ, Swain SL, Woodland DL, Blackman MA, Haynes L. T-cell immunosenescence: lessons learned from mouse models of aging. Trends Immunol. 2009 Jul; 30(7):301-5.
    View in: PubMed
    Score: 0.017
  67. Rogerson BJ, Harris DP, Swain SL, Burgess DO. Germinal center B cells in Peyer's patches of aged mice exhibit a normal activation phenotype and highly mutated IgM genes. Mech Ageing Dev. 2003 Feb; 124(2):155-65.
    View in: PubMed
    Score: 0.011
  68. Dutton RW, Swain SL, Bradley LM. The generation and maintenance of memory T and B cells. Immunol Today. 1999 Jul; 20(7):291-3.
    View in: PubMed
    Score: 0.009
  69. Swain SL, Trefts PE, Tse HY, Dutton RW. The significance of T-B collaboration across haplotype barriers. Cold Spring Harb Symp Quant Biol. 1977; 41 Pt 2:597-609.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.