Scott Shaffer to Animals
This is a "connection" page, showing publications Scott Shaffer has written about Animals.
Connection Strength
0.419
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Shaffer SA, Baker-Lee C, Kennedy J, Lai MS, de Vries P, Buhler K, Singer JW. In vitro and in vivo metabolism of paclitaxel poliglumex: identification of metabolites and active proteases. Cancer Chemother Pharmacol. 2007 Mar; 59(4):537-48.
Score: 0.018
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Sequeira AMM, Rodr?guez JP, Marley SA, Calich HJ, van der Mheen M, VanCompernolle M, Arrowsmith LM, Peel LR, Queiroz N, Vedor M, da Costa I, Mucientes G, Couto A, Humphries NE, Abalo-Morla S, Abascal FJ, Abercrombie DL, Abrantes K, Abreu-Grobois FA, Afonso AS, Afonso P, Ahonen H, ?kesson S, Alfaro-Shigueto J, Andrews RD, Angelier F, Antonopoulou M, Arata JA, Araujo G, Arauz R, Arcos JM, Arregui I, Arrizabalaga H, Auger-M?th? M, Bach S, Bailleul F, Baird RW, Balazs GH, Barco SG, Barnett A, Baverstock W, Baylis AMM, Beard A, B?cares J, Belda EJ, Bell I, Bennison A, Benson SR, Bernal D, Berumen ML, Bessudo S, Bezerra NPA, Blaison AV, Blanco GS, Block BA, Bolton M, Bond ME, Bonfil R, Braun CD, Broderick AC, Brooke ML, Brooks AML, Brooks EJ, Bruno IM, Burns JM, Byrne ME, Campana SE, Campbell HA, Campbell RA, Carlisle A, Carmichael RH, Carroll G, Casale P, Ceia FR, Chapman DD, Chapple TK, Charrassin JB, Chiaradia A, Chisholm J, Clarke CR, Clay TA, Cleguer C, Clingham E, Clua EEG, Cochran JEM, Constantine R, Cooper RW, Crochelet E, Cronin M, Cuevas E, DaCosta KP, Dagorn L, Daly R, Davis RW, de Bruyn PJN, Delgado-Trejo C, Dellinger T, Derville S, Diamant S, DiMatteo A, Dodge KL, Doherty PD, Double MC, Dove ADM, Doyle TK, Drew MJ, Dubbs LL, Duffy CAJ, Dutton PH, Edwards EWJ, Einoder LD, Erdmann MV, Espinoza E, Esteban N, Fagundes AI, Feare C, Ferguson SH, Ferreira LC, Ferretti F, Filmalter J, Finucci B, Fischer GC, Fitzpatrick RJ, Fontes J, Formia A, Fossette S, Francis MP, Friedlaender AS, Furtado M, Gallagher AJ, Garrigue C, Gennari E, Gilchrist HG, Godley BJ, Goldsworthy SD, Gollock M, Carman VG, Grecian WJ, Green JR, Guinet C, Gustafson J, Guttridge TL, Guzman HM, Hamer D, Hamer KC, Hammerschlag N, Hammill MO, Harman L, Harrison E, Hart CE, Harris AE, Hastie G, Hazin FHV, Heard M, Hearn AR, Heide-J?rgensen MP, Henry L, Henry RW, Hernandez VG, Herrera AE, Hindell MA, Holdsworth JC, Holmes BJ, Howey LA, Hoyos Padilla EM, Huckstadt LA, Hueter RE, Lara PH, Hussey NE, Huveneers C, Hyland K, Irion DT, Jacoby DMP, Jaeger A, Jaidah MY, Jessopp M, Jewell OJD, Johnson R, Jones CG, Jonsen ID, Jordan LKB, Jorgensen SJ, Kato A, Ketchum JT, Kitaysky AS, Klimley AP, Kock AA, Koen P, Archila FL, Lana FO, Lane JV, Le Corre M, Lea MA, Lea J, Leat EHK, Lee OA, Levenson JJ, Ley-Qui?onez CP, Llewellyn F, Lockhart G, Lopez GG, Mendilaharsu ML, Lowther AD, Luschi P, Lutcavage ME, Lyon WS, Macena BCL, Mackay AI, Madden CA, Mallory ML, Mangel JC, Manning M, Mansfield KL, March D, Marco A, Marcoux M, Acu?a-Marrero D, Marsh H, Marshall H, Mate B, McAllister JD, McGuire RL, McKenzie J, McLeay L, McMahon CR, Modest M, Morris J, Muelbert MMC, Namboothri N, Nichols WJ, Nicoll MAC, Norman BM, Norris K, Olsen E, Oppel S, Orlowski S, Pagano AM, Page B, Paiva VH, Palacios DM, Papastamatiou YP, Parker DM, Pattiaratchi C, Peckham H, Pe?aherrera-Palma CR, Pepperell JG, Phillips RA, Pierce SJ, Pikesley SK, Pilcher NJ, Pinet P, Pinkerton M, Pirotta E, Plot V, Powell AN, Powers KD, Prebble CEM, Preston TJ, Prieto R, Prosdocimi L, Quinn JL, Quintero LM, Raclot T, Ramirez I, Ram?rez-Mac?as D, Ramos JA, Read AJ, Ream R, Rees AF, Reina RD, Reisinger RR, Revuelta O, Reynolds SD, Richardson AJ, Riekkola L, Riet-Sapriza FG, Robinson DP, Robinson PW, Rocha CFD, Rogers TL, Rohner CA, Ropert-Coudert Y, Ross M, Rowat DRL, Ruhomaun K, Sagar PM, Samoilys MA, Sanchez S, Sandoval-Lugo AG, Dos Santos EAP, Santos AM, Scales KL, Schofield G, Semmens JM, Setyawan E, Shaffer SA, Shanker K, Sheaves M, Shillinger GL, Shivji MS, Sianipar A, Silk JRD, Silva MA, Sim J, Simpson SJ, Skomal G, Slip DJ, Smale MJ, Soler GA, Soria M, Sousa LL, Southall EJ, Stahl JC, Stehfest KM, Sterling JT, Stevens JD, Stevens GMW, Stewart JD, Swaminathan A, Takahashi A, Tatayah V, Thiebot JB, Thompson PM, Thorrold SR, Thums M, Tom?s J, Torres LG, Towner A, Trathan PN, Tyminski JP, Sagarminaga van Buiten R, Van Dam RP, Vandeperre F, Varo-Cruz N, Vaudo JJ, Vely M, Villegas-Amtmann S, Vincent C, Waayers D, et al. Global tracking of marine megafauna space use reveals how to achieve conservation targets. Science. 2025 Jun 05; 388(6751):1086-1097.
Score: 0.017
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Gilmour ME, Pollock K, Adams J, Block BA, Caselle JE, Filous A, Friedlander AM, Game ET, Hazen EL, Hill M, Holmes ND, Lafferty KD, Maxwell SM, McCauley DJ, Schallert R, Shaffer SA, Wolff NH, Wegmann A. Multi-Species Telemetry Quantifies Current and Future Efficacy of a Remote Marine Protected Area. Glob Chang Biol. 2025 Apr; 31(4):e70138.
Score: 0.016
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Humphries F, Shmuel-Galia L, Jiang Z, Zhou JY, Barasa L, Mondal S, Wilson R, Sultana N, Shaffer SA, Ng SL, Pesiridis GS, Thompson PR, Fitzgerald KA. Targeting STING oligomerization with small-molecule inhibitors. Proc Natl Acad Sci U S A. 2023 08 15; 120(33):e2305420120.
Score: 0.015
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Mondal S, Chen Y, Lockbaum GJ, Sen S, Chaudhuri S, Reyes AC, Lee JM, Kaur AN, Sultana N, Cameron MD, Shaffer SA, Schiffer CA, Fitzgerald KA, Thompson PR. Dual Inhibitors of Main Protease (MPro) and Cathepsin L as Potent Antivirals against SARS-CoV2. J Am Chem Soc. 2022 11 23; 144(46):21035-21045.
Score: 0.014
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Wang J, Zhang Y, Mendonca CA, Yukselen O, Muneeruddin K, Ren L, Liang J, Zhou C, Xie J, Li J, Jiang Z, Kucukural A, Shaffer SA, Gao G, Wang D. AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice. Nature. 2022 04; 604(7905):343-348.
Score: 0.013
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Smith TC, Vasilakos G, Shaffer SA, Puglise JM, Chou CH, Barton ER, Luna EJ. Novel ?-sarcoglycan interactors in murine muscle membranes. Skelet Muscle. 2022 01 22; 12(1):2.
Score: 0.013
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Shmuel-Galia L, Humphries F, Lei X, Ceglia S, Wilson R, Jiang Z, Ketelut-Carneiro N, Foley SE, Pechhold S, Houghton J, Muneeruddin K, Shaffer SA, McCormick BA, Reboldi A, Ward D, Marshak-Rothstein A, Fitzgerald KA. Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells. Immunity. 2021 06 08; 54(6):1137-1153.e8.
Score: 0.013
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Humphries F, Shmuel-Galia L, Ketelut-Carneiro N, Li S, Wang B, Nemmara VV, Wilson R, Jiang Z, Khalighinejad F, Muneeruddin K, Shaffer SA, Dutta R, Ionete C, Pesiridis S, Yang S, Thompson PR, Fitzgerald KA. Succination inactivates gasdermin D and blocks pyroptosis. Science. 2020 09 25; 369(6511):1633-1637.
Score: 0.012
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Shaffer SA, Tolmachev A, Prior DC, Anderson GA, Udseth HR, Smith RD. Characterization of an improved electrodynamic ion funnel interface for electrospray ionization mass spectrometry. Anal Chem. 1999 Aug 01; 71(15):2957-64.
Score: 0.011
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Baron DM, Matheny T, Lin YC, Leszyk JD, Kenna K, Gall KV, Santos DP, Tischbein M, Funes S, Hayward LJ, Kiskinis E, Landers JE, Parker R, Shaffer SA, Bosco DA. Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS. Hum Mol Genet. 2019 07 01; 28(13):2143-2160.
Score: 0.011
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Nanaware PP, Jurewicz MM, Leszyk JD, Shaffer SA, Stern LJ. HLA-DO Modulates the Diversity of the MHC-II Self-peptidome. Mol Cell Proteomics. 2019 03; 18(3):490-503.
Score: 0.011
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Rittershaus ESC, Baek SH, Krieger IV, Nelson SJ, Cheng YS, Nambi S, Baker RE, Leszyk JD, Shaffer SA, Sacchettini JC, Sassetti CM. A Lysine Acetyltransferase Contributes to the Metabolic Adaptation to Hypoxia in Mycobacterium tuberculosis. Cell Chem Biol. 2018 12 20; 25(12):1495-1505.e3.
Score: 0.011
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Shaffer SA, Prior DC, Anderson GA, Udseth HR, Smith RD. An ion funnel interface for improved ion focusing and sensitivity using electrospray ionization mass spectrometry. Anal Chem. 1998 Oct 01; 70(19):4111-9.
Score: 0.010
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Haraszti RA, Miller R, Stoppato M, Sere YY, Coles A, Didiot MC, Wollacott R, Sapp E, Dubuke ML, Li X, Shaffer SA, DiFiglia M, Wang Y, Aronin N, Khvorova A. Exosomes Produced from 3D Cultures of MSCs by Tangential Flow Filtration Show Higher Yield and Improved Activity. Mol Ther. 2018 12 05; 26(12):2838-2847.
Score: 0.010
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Saha B, Momen-Heravi F, Furi I, Kodys K, Catalano D, Gangopadhyay A, Haraszti R, Satishchandran A, Iracheta-Vellve A, Adejumo A, Shaffer SA, Szabo G. Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation through heat shock protein 90. Hepatology. 2018 05; 67(5):1986-2000.
Score: 0.010
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Pacheco NL, Heaven MR, Holt LM, Crossman DK, Boggio KJ, Shaffer SA, Flint DL, Olsen ML. RNA sequencing and proteomics approaches reveal novel deficits in the cortex of Mecp2-deficient mice, a model for Rett syndrome. Mol Autism. 2017; 8:56.
Score: 0.010
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Thompson MF, Poirier GL, D?vila-Garc?a MI, Huang W, Tam K, Robidoux M, Dubuke ML, Shaffer SA, Colon-Perez L, Febo M, DiFranza JR, King JA. Menthol enhances nicotine-induced locomotor sensitization and in vivo functional connectivity in adolescence. J Psychopharmacol. 2018 03; 32(3):332-343.
Score: 0.010
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Mishra BB, Lovewell RR, Olive AJ, Zhang G, Wang W, Eugenin E, Smith CM, Phuah JY, Long JE, Dubuke ML, Palace SG, Goguen JD, Baker RE, Nambi S, Mishra R, Booty MG, Baer CE, Shaffer SA, Dartois V, McCormick BA, Chen X, Sassetti CM. Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis. Nat Microbiol. 2017 May 15; 2:17072.
Score: 0.010
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Chen L, Paquette N, Mamoor S, Rus F, Nandy A, Leszyk J, Shaffer SA, Silverman N. Innate immune signaling in Drosophila is regulated by transforming growth factor ? (TGF?)-activated kinase (Tak1)-triggered ubiquitin editing. J Biol Chem. 2017 05 26; 292(21):8738-8749.
Score: 0.009
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Ortiz-Miranda S, Ji R, Jurczyk A, Aryee KE, Mo S, Fletcher T, Shaffer SA, Greiner DL, Bortell R, Gregg RG, Cheng A, Hennings LJ, Rittenhouse AR. A novel transgenic mouse model of lysosomal storage disorder. Am J Physiol Gastrointest Liver Physiol. 2016 11 01; 311(5):G903-G919.
Score: 0.009
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Clement CC, Becerra A, Yin L, Zolla V, Huang L, Merlin S, Follenzi A, Shaffer SA, Stern LJ, Santambrogio L. The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity. J Biol Chem. 2016 Mar 11; 291(11):5576-5595.
Score: 0.009
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Nasipak BT, Padilla-Benavides T, Green KM, Leszyk JD, Mao W, Konda S, Sif S, Shaffer SA, Ohkawa Y, Imbalzano AN. Opposing calcium-dependent signalling pathways control skeletal muscle differentiation by regulating a chromatin remodelling enzyme. Nat Commun. 2015 Jun 17; 6:7441.
Score: 0.008
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Nambi S, Long JE, Mishra BB, Baker R, Murphy KC, Olive AJ, Nguyen HP, Shaffer SA, Sassetti CM. The Oxidative Stress Network of Mycobacterium tuberculosis Reveals Coordination between Radical Detoxification Systems. Cell Host Microbe. 2015 Jun 10; 17(6):829-37.
Score: 0.008
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Weismann CM, Ferreira J, Keeler AM, Su Q, Qui L, Shaffer SA, Xu Z, Gao G, Sena-Esteves M. Systemic AAV9 gene transfer in adult GM1 gangliosidosis mice reduces lysosomal storage in CNS and extends lifespan. Hum Mol Genet. 2015 Aug 01; 24(15):4353-64.
Score: 0.008
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Vodicka P, Mo S, Tousley A, Green KM, Sapp E, Iuliano M, Sadri-Vakili G, Shaffer SA, Aronin N, DiFiglia M, Kegel-Gleason KB. Mass Spectrometry Analysis of Wild-Type and Knock-in Q140/Q140 Huntington's Disease Mouse Brains Reveals Changes in Glycerophospholipids Including Alterations in Phosphatidic Acid and Lyso-Phosphatidic Acid. J Huntingtons Dis. 2015; 4(2):187-201.
Score: 0.008
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Rotunno MS, Auclair JR, Maniatis S, Shaffer SA, Agar J, Bosco DA. Identification of a misfolded region in superoxide dismutase 1 that is exposed in amyotrophic lateral sclerosis. J Biol Chem. 2014 Oct 10; 289(41):28527-38.
Score: 0.008
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Swiderski K, Shaffer SA, Gallis B, Odom GL, Arnett AL, Scott Edgar J, Baum DM, Chee A, Naim T, Gregorevic P, Murphy KT, Moody J, Goodlett DR, Lynch GS, Chamberlain JS. Phosphorylation within the cysteine-rich region of dystrophin enhances its association with ?-dystroglycan and identifies a potential novel therapeutic target for skeletal muscle wasting. Hum Mol Genet. 2014 Dec 20; 23(25):6697-711.
Score: 0.008
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Ambade A, Catalano D, Lim A, Kopoyan A, Shaffer SA, Mandrekar P. Inhibition of heat shock protein 90 alleviates steatosis and macrophage activation in murine alcoholic liver injury. J Hepatol. 2014 Oct; 61(4):903-11.
Score: 0.008
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Valencia A, Sapp E, Kimm JS, McClory H, Ansong KA, Yohrling G, Kwak S, Kegel KB, Green KM, Shaffer SA, Aronin N, DiFiglia M. Striatal synaptosomes from Hdh140Q/140Q knock-in mice have altered protein levels, novel sites of methionine oxidation, and excess glutamate release after stimulation. J Huntingtons Dis. 2013; 2(4):459-75.
Score: 0.007
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Rudra D, deRoos P, Chaudhry A, Niec RE, Arvey A, Samstein RM, Leslie C, Shaffer SA, Goodlett DR, Rudensky AY. Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nat Immunol. 2012 Oct; 13(10):1010-9.
Score: 0.007
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Paquette N, Conlon J, Sweet C, Rus F, Wilson L, Pereira A, Rosadini CV, Goutagny N, Weber AN, Lane WS, Shaffer SA, Maniatis S, Fitzgerald KA, Stuart L, Silverman N. Serine/threonine acetylation of TGF?-activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12710-5.
Score: 0.007
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Li Y, Powell DA, Shaffer SA, Rasko DA, Pelletier MR, Leszyk JD, Scott AJ, Masoudi A, Goodlett DR, Wang X, Raetz CR, Ernst RK. LPS remodeling is an evolved survival strategy for bacteria. Proc Natl Acad Sci U S A. 2012 May 29; 109(22):8716-21.
Score: 0.007
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Keeler AM, Conlon T, Walter G, Zeng H, Shaffer SA, Dungtao F, Erger K, Cossette T, Tang Q, Mueller C, Flotte TR. Long-term correction of very long-chain acyl-coA dehydrogenase deficiency in mice using AAV9 gene therapy. Mol Ther. 2012 Jun; 20(6):1131-8.
Score: 0.007
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Thatcher JE, Buttrick B, Shaffer SA, Shimshoni JA, Goodlett DR, Nelson WL, Isoherranen N. Substrate specificity and ligand interactions of CYP26A1, the human liver retinoic acid hydroxylase. Mol Pharmacol. 2011 Aug; 80(2):228-39.
Score: 0.006
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Panchaud A, Jung S, Shaffer SA, Aitchison JD, Goodlett DR. Faster, quantitative, and accurate precursor acquisition independent from ion count. Anal Chem. 2011 Mar 15; 83(6):2250-7.
Score: 0.006
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Chakrabarti L, Zahra R, Jackson SM, Kazemi-Esfarjani P, Sopher BL, Mason AG, Toneff T, Ryu S, Shaffer S, Kansy JW, Eng J, Merrihew G, MacCoss MJ, Murphy A, Goodlett DR, Hook V, Bennett CL, Pallanck LJ, La Spada AR. Mitochondrial dysfunction in NnaD mutant flies and Purkinje cell degeneration mice reveals a role for Nna proteins in neuronal bioenergetics. Neuron. 2010 Jun 24; 66(6):835-47.
Score: 0.006
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Gharib SA, Nguyen E, Altemeier WA, Shaffer SA, Doneanu CE, Goodlett DR, Schnapp LM. Of mice and men: comparative proteomics of bronchoalveolar fluid. Eur Respir J. 2010 Jun; 35(6):1388-95.
Score: 0.006
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Parra MC, Shaffer SA, Hajjar AM, Gallis BM, Hager A, Goodlett DR, Guina T, Miller S, Collins CM. Identification, cloning, expression, and purification of Francisella lpp3: an immunogenic lipoprotein. Microbiol Res. 2010 Sep 20; 165(7):531-45.
Score: 0.006
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Tsai YS, Scherl A, Shaw JL, MacKay CL, Shaffer SA, Langridge-Smith PR, Goodlett DR. Precursor ion independent algorithm for top-down shotgun proteomics. J Am Soc Mass Spectrom. 2009 Nov; 20(11):2154-66.
Score: 0.006
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Moore NH, Costa LG, Shaffer SA, Goodlett DR, Guizzetti M. Shotgun proteomics implicates extracellular matrix proteins and protease systems in neuronal development induced by astrocyte cholinergic stimulation. J Neurochem. 2009 Feb; 108(4):891-908.
Score: 0.005
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Kanistanon D, Hajjar AM, Pelletier MR, Gallagher LA, Kalhorn T, Shaffer SA, Goodlett DR, Rohmer L, Brittnacher MJ, Skerrett SJ, Ernst RK. A Francisella mutant in lipid A carbohydrate modification elicits protective immunity. PLoS Pathog. 2008 Feb 08; 4(2):e24.
Score: 0.005
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Prakash A, Piening B, Whiteaker J, Zhang H, Shaffer SA, Martin D, Hohmann L, Cooke K, Olson JM, Hansen S, Flory MR, Lee H, Watts J, Goodlett DR, Aebersold R, Paulovich A, Schwikowski B. Assessing bias in experiment design for large scale mass spectrometry-based quantitative proteomics. Mol Cell Proteomics. 2007 Oct; 6(10):1741-8.
Score: 0.005
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Trute M, Gallis B, Doneanu C, Shaffer S, Goodlett D, Gallagher E. Characterization of hepatic glutathione S-transferases in coho salmon (Oncorhynchus kisutch). Aquat Toxicol. 2007 Feb 28; 81(2):126-36.
Score: 0.005
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Hajjar AM, Harvey MD, Shaffer SA, Goodlett DR, Sj?stedt A, Edebro H, Forsman M, Bystr?m M, Pelletier M, Wilson CB, Miller SI, Skerrett SJ, Ernst RK. Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors. Infect Immun. 2006 Dec; 74(12):6730-8.
Score: 0.005
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Singer JW, Shaffer S, Baker B, Bernareggi A, Stromatt S, Nienstedt D, Besman M. Paclitaxel poliglumex (XYOTAX; CT-2103): an intracellularly targeted taxane. Anticancer Drugs. 2005 Mar; 16(3):243-54.
Score: 0.004
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Singer JW, Baker B, De Vries P, Kumar A, Shaffer S, Vawter E, Bolton M, Garzone P. Poly-(L)-glutamic acid-paclitaxel (CT-2103) [XYOTAX], a biodegradable polymeric drug conjugate: characterization, preclinical pharmacology, and preliminary clinical data. Adv Exp Med Biol. 2003; 519:81-99.
Score: 0.004