Eicke Latz to Macrophages
This is a "connection" page, showing publications Eicke Latz has written about Macrophages.
Connection Strength
7.048
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Budden CF, Gearing LJ, Kaiser R, Standke L, Hertzog PJ, Latz E. Inflammasome-induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses. J Extracell Vesicles. 2021 08; 10(10):e12127.
Score: 0.501
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Lauterbach MA, Hanke JE, Serefidou M, Mangan MSJ, Kolbe CC, Hess T, Rothe M, Kaiser R, Hoss F, Gehlen J, Engels G, Kreutzenbeck M, Schmidt SV, Christ A, Imhof A, Hiller K, Latz E. Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase. Immunity. 2019 12 17; 51(6):997-1011.e7.
Score: 0.447
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Mangan MS, Latz E. TAK1ng control: TAK1 restrains NLRP3 activation. J Exp Med. 2018 04 02; 215(4):1007-1008.
Score: 0.395
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De Nardo D, Kalvakolanu DV, Latz E. Immortalization of Murine Bone Marrow-Derived Macrophages. Methods Mol Biol. 2018; 1784:35-49.
Score: 0.391
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Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Bj?rkhem I, Gustafsson J?, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, L?tjohann D, Latz E. Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Sci Transl Med. 2016 Apr 06; 8(333):333ra50.
Score: 0.346
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Schultze JL, Freeman T, Hume DA, Latz E. A transcriptional perspective on human macrophage biology. Semin Immunol. 2015 Feb; 27(1):44-50.
Score: 0.323
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Christ A, Latz E. LOX-1 and mitochondria: an inflammatory relationship. Cardiovasc Res. 2014 Sep 01; 103(4):435-7.
Score: 0.309
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De Nardo D, Labzin LI, Kono H, Seki R, Schmidt SV, Beyer M, Xu D, Zimmer S, Lahrmann C, Schildberg FA, Vogelhuber J, Kraut M, Ulas T, Kerksiek A, Krebs W, Bode N, Grebe A, Fitzgerald ML, Hernandez NJ, Williams BR, Knolle P, Kneilling M, R?cken M, L?tjohann D, Wright SD, Schultze JL, Latz E. High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3. Nat Immunol. 2014 Feb; 15(2):152-60.
Score: 0.295
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Wang W, Dernst A, Martin B, Lorenzi L, Cadefau-Fabregat M, Phulphagar K, Wagener A, Budden C, Stair N, Wagner T, F?rber H, Jaensch A, Stahl R, Duthie F, Schmidt SV, Coll RC, Meissner F, Cuartero S, Latz E, Mangan MSJ. Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation. Cell Rep. 2024 09 24; 43(9):114736.
Score: 0.155
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Auger JP, Zimmermann M, Faas M, Stifel U, Chambers D, Krishnacoumar B, Taudte RV, Grund C, Erdmann G, Scholtysek C, Uderhardt S, Ben Brahim O, Pascual Mat? M, Stoll C, B?ttcher M, Palumbo-Zerr K, Mangan MSJ, Dzamukova M, Kieler M, Hofmann M, Bl?ml S, Schabbauer G, Mougiakakos D, Sonnewald U, Hartmann F, Simon D, Kleyer A, Gr?neboom A, Finotto S, Latz E, Hofmann J, Schett G, Tuckermann J, Kr?nke G. Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids. Nature. 2024 May; 629(8010):184-192.
Score: 0.151
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Lovotti M, Mangan MSJ, McManus RM, Shkarina K, Vasconcelos MB, Latz E. Monitoring of Inflammasome Activation of Macrophages and Microglia In Vitro, Part 1: Cell Preparation and Inflammasome Stimulation. Methods Mol Biol. 2024; 2713:407-429.
Score: 0.148
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Lovotti M, Mangan MSJ, McManus RM, Shkarina K, Vasconcelos MB, Latz E. Monitoring of Inflammasome Activation of Macrophages and Microglia In Vitro, Part 2: Assessing Inflammasome Activation. Methods Mol Biol. 2024; 2713:431-451.
Score: 0.148
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Mangan MSJ, Gorki F, Krause K, Heinz A, Pankow A, Ebert T, Jahn D, Hiller K, Hornung V, Maurer M, Schmidt FI, Gerhard R, Latz E. Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever. PLoS Biol. 2022 11; 20(11):e3001351.
Score: 0.137
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He W, Henne A, Lauterbach M, Gei?mar E, Nikolka F, Kho C, Heinz A, Dostert C, Grusdat M, Cordes T, H?rm J, Goldmann O, Ewen A, Verschueren C, Blay-Cadanet J, Geffers R, Garritsen H, Kneiling M, Holm CK, Metallo CM, Medina E, Abdullah Z, Latz E, Brenner D, Hiller K. Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages. Nat Metab. 2022 05; 4(5):524-533.
Score: 0.133
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Orecchioni M, Kobiyama K, Winkels H, Ghosheh Y, McArdle S, Mikulski Z, Kiosses WB, Fan Z, Wen L, Jung Y, Roy P, Ali AJ, Miyamoto Y, Mangan M, Makings J, Wang Z, Denn A, Vallejo J, Owens M, Durant CP, Braumann S, Mader N, Li L, Matsunami H, Eckmann L, Latz E, Wang Z, Hazen SL, Ley K. Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production. Science. 2022 Jan 14; 375(6577):214-221.
Score: 0.129
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Liu K, Sato R, Shibata T, Hiranuma R, Reuter T, Fukui R, Zhang Y, Ichinohe T, Ozawa M, Yoshida N, Latz E, Miyake K. Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages. Int Immunol. 2021 08 23; 33(9):479-490.
Score: 0.126
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Braga TT, Davanso MR, Mendes D, de Souza TA, de Brito AF, Cruz MC, Hiyane MI, de Lima DS, Nunes V, de F?tima Giarola J, Souto DEP, Pr?chnicki T, Lauterbach M, Biscaia SMP, de Freitas RA, Curi R, Pontillo A, Latz E, Camara NOS. Sensing soluble uric acid by Naip1-Nlrp3 platform. Cell Death Dis. 2021 02 05; 12(2):158.
Score: 0.121
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Sato R, Reuter T, Hiranuma R, Shibata T, Fukui R, Motoi Y, Murakami Y, Tsukamoto H, Yamazaki S, Liu K, Saitoh SI, Latz E, Miyake K. The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages. Int Immunol. 2020 11 23; 32(12):785-798.
Score: 0.119
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Balic JJ, Albargy H, Luu K, Kirby FJ, Jayasekara WSN, Mansell F, Garama DJ, De Nardo D, Baschuk N, Louis C, Humphries F, Fitzgerald K, Latz E, Gough DJ, Mansell A. STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1? expression. Nat Commun. 2020 07 30; 11(1):3816.
Score: 0.117
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Selkrig J, Li N, Hausmann A, Mangan MSJ, Zietek M, Mateus A, Bobonis J, Sueki A, Imamura H, El Debs B, Sigismondo G, Florea BI, Overkleeft HS, Kopitar-Jerala N, Turk B, Beltrao P, Savitski MM, Latz E, Hardt WD, Krijgsveld J, Typas A. Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection. Nat Microbiol. 2020 09; 5(9):1119-1133.
Score: 0.116
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Khan NS, Lukason DP, Feliu M, Ward RA, Lord AK, Reedy JL, Ramirez-Ortiz ZG, Tam JM, Kasperkovitz PV, Negoro PE, Vyas TD, Xu S, Brinkmann MM, Acharaya M, Artavanis-Tsakonas K, Frickel EM, Becker CE, Dagher Z, Kim YM, Latz E, Ploegh HL, Mansour MK, Miranti CK, Levitz SM, Vyas JM. CD82 controls CpG-dependent TLR9 signaling. FASEB J. 2019 11; 33(11):12500-12514.
Score: 0.109
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Aftabizadeh M, Tatarek-Nossol M, Andreetto E, El Bounkari O, Kipp M, Beyer C, Latz E, Bernhagen J, Kapurniotu A. Blocking Inflammasome Activation Caused by ?-Amyloid Peptide (A?) and Islet Amyloid Polypeptide (IAPP) through an IAPP Mimic. ACS Chem Neurosci. 2019 08 21; 10(8):3703-3717.
Score: 0.109
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Hoss F, Mueller JL, Rojas Ringeling F, Rodriguez-Alcazar JF, Brinkschulte R, Seifert G, Stahl R, Broderick L, Putnam CD, Kolodner RD, Canzar S, Geyer M, Hoffman HM, Latz E. Alternative splicing regulates stochastic NLRP3 activity. Nat Commun. 2019 07 19; 10(1):3238.
Score: 0.109
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Rodr?guez-Alc?zar JF, Ataide MA, Engels G, Schmitt-Mabmunyo C, Garbi N, Kastenm?ller W, Latz E, Franklin BS. Charcot-Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1? Inflammation in Human Macrophages. J Immunol. 2019 01 15; 202(2):550-558.
Score: 0.104
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K?ppert S, B?scher A, Babler A, Ghallab A, Buhl EM, Latz E, Hengstler JG, Smith ER, Jahnen-Dechent W. Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity. Front Immunol. 2018; 9:1991.
Score: 0.102
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Pelka K, Bertheloot D, Reimer E, Phulphagar K, Schmidt SV, Christ A, Stahl R, Watson N, Miyake K, Hacohen N, Haas A, Brinkmann MM, Marshak-Rothstein A, Meissner F, Latz E. The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport. Immunity. 2018 05 15; 48(5):911-922.e7.
Score: 0.100
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Cardona Gloria Y, Latz E, De Nardo D. Generation of Innate Immune Reporter Cells Using Retroviral Transduction. Methods Mol Biol. 2018; 1714:97-117.
Score: 0.098
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Sander J, Schmidt SV, Cirovic B, McGovern N, Papantonopoulou O, Hardt AL, Aschenbrenner AC, Kreer C, Quast T, Xu AM, Schmidleithner LM, Theis H, Thi Huong LD, Sumatoh HRB, Lauterbach MAR, Schulte-Schrepping J, G?nther P, Xue J, Ba?ler K, Ulas T, Klee K, Katzmarski N, Herresthal S, Krebs W, Martin B, Latz E, H?ndler K, Kraut M, Kolanus W, Beyer M, Falk CS, Wiegmann B, Burgdorf S, Melosh NA, Newell EW, Ginhoux F, Schlitzer A, Schultze JL. Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2. Immunity. 2017 12 19; 47(6):1051-1066.e12.
Score: 0.097
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Li T, He J, Horvath G, Pr?chnicki T, Latz E, Takeoka S. Lysine-containing cationic liposomes activate the NLRP3 inflammasome: Effect of a spacer between the head group and the hydrophobic moieties of the lipids. Nanomedicine. 2018 02; 14(2):279-288.
Score: 0.097
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Braga TT, Forni MF, Correa-Costa M, Ramos RN, Barbuto JA, Branco P, Castoldi A, Hiyane MI, Davanso MR, Latz E, Franklin BS, Kowaltowski AJ, Camara NO. Soluble Uric Acid Activates the NLRP3 Inflammasome. Sci Rep. 2017 01 13; 7:39884.
Score: 0.091
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Pfeiler S, Khandagale AB, Magenau A, Nichols M, Heijnen HF, Rinninger F, Ziegler T, Seveau S, Schubert S, Zahler S, Verschoor A, Latz E, Massberg S, Gaus K, Engelmann B. Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI. Sci Rep. 2016 10 03; 6:34440.
Score: 0.090
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Sun J, Li N, Oh KS, Dutta B, Vayttaden SJ, Lin B, Ebert TS, De Nardo D, Davis J, Bagirzadeh R, Lounsbury NW, Pasare C, Latz E, Hornung V, Fraser ID. Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use. Sci Signal. 2016 Jan 05; 9(409):ra3.
Score: 0.085
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Labzin LI, Schmidt SV, Masters SL, Beyer M, Krebs W, Klee K, Stahl R, L?tjohann D, Schultze JL, Latz E, De Nardo D. ATF3 Is a Key Regulator of Macrophage IFN Responses. J Immunol. 2015 Nov 01; 195(9):4446-55.
Score: 0.083
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Franklin BS, Bossaller L, De Nardo D, Ratter JM, Stutz A, Engels G, Brenker C, Nordhoff M, Mirandola SR, Al-Amoudi A, Mangan MS, Zimmer S, Monks BG, Fricke M, Schmidt RE, Espevik T, Jones B, Jarnicki AG, Hansbro PM, Busto P, Marshak-Rothstein A, Hornemann S, Aguzzi A, Kastenm?ller W, Latz E. The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation. Nat Immunol. 2014 Aug; 15(8):727-37.
Score: 0.076
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Schmidt-Lauber C, Bossaller L, Abujudeh HH, Vladimer GI, Christ A, Fitzgerald KA, Latz E, Gravallese EM, Marshak-Rothstein A, Kay J. Gadolinium-based compounds induce NLRP3-dependent IL-1? production and peritoneal inflammation. Ann Rheum Dis. 2015 Nov; 74(11):2062-9.
Score: 0.076
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Hernandez JC, Latz E, Urcuqui-Inchima S. HIV-1 induces the first signal to activate the NLRP3 inflammasome in monocyte-derived macrophages. Intervirology. 2014; 57(1):36-42.
Score: 0.072
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Duewell P, Latz E. Assessment and quantification of crystal-induced lysosomal damage. Methods Mol Biol. 2013; 1040:19-27.
Score: 0.069
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Stutz A, Horvath GL, Monks BG, Latz E. ASC speck formation as a readout for inflammasome activation. Methods Mol Biol. 2013; 1040:91-101.
Score: 0.069
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Rathinam VA, Jiang Z, Waggoner SN, Sharma S, Cole LE, Waggoner L, Vanaja SK, Monks BG, Ganesan S, Latz E, Hornung V, Vogel SN, Szomolanyi-Tsuda E, Fitzgerald KA. The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat Immunol. 2010 May; 11(5):395-402.
Score: 0.057
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Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, MacDonald K, Speert D, Fernandes-Alnemri T, Wu J, Monks BG, Fitzgerald KA, Hornung V, Latz E. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol. 2009 Jul 15; 183(2):787-91.
Score: 0.054
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Charrel-Dennis M, Latz E, Halmen KA, Trieu-Cuot P, Fitzgerald KA, Kasper DL, Golenbock DT. TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA. Cell Host Microbe. 2008 Dec 11; 4(6):543-54.
Score: 0.052
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Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, Latz E. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol. 2008 Aug; 9(8):847-56.
Score: 0.051
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Tamehiro N, Zhou S, Okuhira K, Benita Y, Brown CE, Zhuang DZ, Latz E, Hornemann T, von Eckardstein A, Xavier RJ, Freeman MW, Fitzgerald ML. SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter. Biochemistry. 2008 Jun 10; 47(23):6138-47.
Score: 0.050
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Rowe DC, McGettrick AF, Latz E, Monks BG, Gay NJ, Yamamoto M, Akira S, O'Neill LA, Fitzgerald KA, Golenbock DT. The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction. Proc Natl Acad Sci U S A. 2006 Apr 18; 103(16):6299-304.
Score: 0.043
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Sato R, Liu K, Shibata T, Hoshino K, Yamaguchi K, Miyazaki T, Hiranuma R, Fukui R, Motoi Y, Fukuda-Ohta Y, Zhang Y, Reuter T, Ishida Y, Kondo T, Chiba T, Asahara H, Taoka M, Yamauchi Y, Isobe T, Kaisho T, Furukawa Y, Latz E, Nakatani K, Izumi Y, Nie Y, Taniguchi H, Miyake K. RNase T2 deficiency promotes TLR13-dependent replenishment of tissue-protective Kupffer cells. J Exp Med. 2025 Mar 03; 222(3).
Score: 0.040
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Weiss FD, Alvarez Y, Shakeri F, Sahu A, Leka P, Dernst A, Rollheiser J, Vasconcelos M, Geraci A, Duthie F, Stahl R, Lee HE, Gellner AK, Buness A, Latz E, Meissner F. Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3tm1Flv mice. Cell Death Differ. 2024 Dec; 31(12):1717-1729.
Score: 0.039
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Nickenig M, Mangan MSJ, Lee HE, Symeonidis K, Henne A, Kaiser R, Gei?mar E, Garritsen H, Abdullah Z, Hiller K, Latz E, Lauterbach MA. Cutting Edge: STING Induces ACLY Activation and Metabolic Adaptations in Human Macrophages through TBK1. J Immunol. 2024 01 01; 212(1):7-11.
Score: 0.037
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Bode C, Poth JM, Fox M, Schulz S, Klinman DM, Latz E, Steinhagen F. Cytosolic d-type CpG-oligonucleotides induce a type I interferon response by activating the cGAS-STING signaling pathway. Eur J Immunol. 2021 07; 51(7):1686-1697.
Score: 0.031
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Li T, Zehner M, He J, Pr?chnicki T, Horvath G, Latz E, Burgdorf S, Takeoka S. NLRP3 inflammasome-activating arginine-based liposomes promote antigen presentations in dendritic cells. Int J Nanomedicine. 2019; 14:3503-3516.
Score: 0.027
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Krishnan SM, Ling YH, Huuskes BM, Ferens DM, Saini N, Chan CT, Diep H, Kett MM, Samuel CS, Kemp-Harper BK, Robertson AAB, Cooper MA, Peter K, Latz E, Mansell AS, Sobey CG, Drummond GR, Vinh A. Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension. Cardiovasc Res. 2019 03 15; 115(4):776-787.
Score: 0.027
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De Nardo D, Balka KR, Cardona Gloria Y, Rao VR, Latz E, Masters SL. Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling. J Biol Chem. 2018 09 28; 293(39):15195-15207.
Score: 0.025
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Scheiblich H, Schl?tter A, Golenbock DT, Latz E, Martinez-Martinez P, Heneka MT. Activation of the NLRP3 inflammasome in microglia: the role of ceramide. J Neurochem. 2017 12; 143(5):534-550.
Score: 0.024
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F?lle L, Steiner N, Funke M, Gondorf F, Pfeiffer F, Siegl J, Opitz FV, Ha?el SK, Erazo AB, Schanz O, Stunden HJ, Blank M, Gr?ber C, H?ndler K, Beyer M, Weighardt H, Latz E, Schultze JL, Mayer G, F?rster I. RNA Aptamers Recognizing Murine CCL17 Inhibit T Cell Chemotaxis and Reduce Contact Hypersensitivity In?Vivo. Mol Ther. 2018 01 03; 26(1):95-104.
Score: 0.024
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Tate MD, Ong JDH, Dowling JK, McAuley JL, Robertson AB, Latz E, Drummond GR, Cooper MA, Hertzog PJ, Mansell A. Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition. Sci Rep. 2016 06 10; 6:27912.
Score: 0.022
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Beilharz M, De Nardo D, Latz E, Franklin BS. Measuring NLR Oligomerization II: Detection of ASC Speck Formation by Confocal Microscopy and Immunofluorescence. Methods Mol Biol. 2016; 1417:145-58.
Score: 0.021
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Schneider KM, Bieghs V, Heymann F, Hu W, Dreymueller D, Liao L, Frissen M, Ludwig A, Gassler N, Pabst O, Latz E, Sellge G, Penders J, Tacke F, Trautwein C. CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis. Hepatology. 2015 Nov; 62(5):1405-16.
Score: 0.021
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Eigenbrod T, Pelka K, Latz E, Kreikemeyer B, Dalpke AH. TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes. J Immunol. 2015 Aug 01; 195(3):1092-9.
Score: 0.020
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Verstak B, Stack J, Ve T, Mangan M, Hjerrild K, Jeon J, Stahl R, Latz E, Gay N, Kobe B, Bowie AG, Mansell A. The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4. J Leukoc Biol. 2014 Sep; 96(3):427-36.
Score: 0.019
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Wilson NS, Duewell P, Yang B, Li Y, Marsters S, Koernig S, Latz E, Maraskovsky E, Morelli AB, Schnurr M, Ashkenazi A. Inflammasome-dependent and -independent IL-18 production mediates immunity to the ISCOMATRIX adjuvant. J Immunol. 2014 Apr 01; 192(7):3259-68.
Score: 0.019
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Hett EC, Slater LH, Mark KG, Kawate T, Monks BG, Stutz A, Latz E, Hung DT. Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis. Nat Chem Biol. 2013 Jun; 9(6):398-405.
Score: 0.018
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Hern?ndez JC, Stevenson M, Latz E, Urcuqui-Inchima S. HIV type 1 infection up-regulates TLR2 and TLR4 expression and function in vivo and in vitro. AIDS Res Hum Retroviruses. 2012 Oct; 28(10):1313-28.
Score: 0.016
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Kim S, Bauernfeind F, Ablasser A, Hartmann G, Fitzgerald KA, Latz E, Hornung V. Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome. Eur J Immunol. 2010 Jun; 40(6):1545-51.
Score: 0.014
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Bauer C, Duewell P, Mayer C, Lehr HA, Fitzgerald KA, Dauer M, Tschopp J, Endres S, Latz E, Schnurr M. Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome. Gut. 2010 Sep; 59(9):1192-9.
Score: 0.014
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Gantier MP, Tong S, Behlke MA, Irving AT, Lappas M, Nilsson UW, Latz E, McMillan NA, Williams BR. Rational design of immunostimulatory siRNAs. Mol Ther. 2010 Apr; 18(4):785-95.
Score: 0.014
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Juliana C, Fernandes-Alnemri T, Wu J, Datta P, Solorzano L, Yu JW, Meng R, Quong AA, Latz E, Scott CP, Alnemri ES. Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome. J Biol Chem. 2010 Mar 26; 285(13):9792-9802.
Score: 0.014
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Mann PB, Wolfe D, Latz E, Golenbock D, Preston A, Harvill ET. Comparative toll-like receptor 4-mediated innate host defense to Bordetella infection. Infect Immun. 2005 Dec; 73(12):8144-52.
Score: 0.011