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Jeremy Luban to Humans

This is a "connection" page, showing publications Jeremy Luban has written about Humans.
Connection Strength

1.270
  1. Abajorga M, Yurkovetskiy L, Luban J. piRNA Defense Against Endogenous Retroviruses. Viruses. 2024 Nov 09; 16(11).
    View in: PubMed
    Score: 0.037
  2. Guney MH, Nagalekshmi K, McCauley SM, Carbone C, Aydemir O, Luban J. IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus. Proc Natl Acad Sci U S A. 2024 Jul 16; 121(29):e2404349121.
    View in: PubMed
    Score: 0.036
  3. Wang Y, Lifshitz L, Silverstein NJ, Mintzer E, Luk K, StLouis P, Brehm MA, Wolfe SA, Deeks SG, Luban J. Transcriptional and chromatin profiling of human blood innate lymphoid cell subsets sheds light on HIV-1 pathogenesis. EMBO J. 2023 08 15; 42(16):e114153.
    View in: PubMed
    Score: 0.034
  4. Lemieux JE, Luban J. Consulting the Oracle of SARS-CoV-2 Infection. J Infect Dis. 2022 04 01; 225(7):1115-1117.
    View in: PubMed
    Score: 0.031
  5. Silverstein NJ, Wang Y, Manickas-Hill Z, Carbone C, Dauphin A, Boribong BP, Loiselle M, Davis J, Leonard MM, Kuri-Cervantes L, Meyer NJ, Betts MR, Li JZ, Walker BD, Yu XG, Yonker LM, Luban J. Innate lymphoid cells and COVID-19 severity in SARS-CoV-2 infection. Elife. 2022 03 11; 11.
    View in: PubMed
    Score: 0.031
  6. Diehl WE, Guney MH, Vanzo T, Kyawe PP, White JM, Pizzato M, Luban J. Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity. Viruses. 2021 06 30; 13(7).
    View in: PubMed
    Score: 0.029
  7. Silverstein NJ, Luban J. Lessons from a local effort to screen for SARS-CoV-2. Proc Natl Acad Sci U S A. 2021 06 29; 118(26).
    View in: PubMed
    Score: 0.029
  8. Luban J, Sattler RA, M?hlberger E, Graci JD, Cao L, Weetall M, Trotta C, Colacino JM, Bavari S, Strambio-De-Castillia C, Suder EL, Wang Y, Soloveva V, Cintron-Lue K, Naryshkin NA, Pykett M, Welch EM, O'Keefe K, Kong R, Goodwin E, Jacobson A, Paessler S, Peltz SW. The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines. Virus Res. 2021 01 15; 292:198246.
    View in: PubMed
    Score: 0.028
  9. Yurkovetskiy L, Wang X, Pascal KE, Tomkins-Tinch C, Nyalile TP, Wang Y, Baum A, Diehl WE, Dauphin A, Carbone C, Veinotte K, Egri SB, Schaffner SF, Lemieux JE, Munro JB, Rafique A, Barve A, Sabeti PC, Kyratsous CA, Dudkina NV, Shen K, Luban J. Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant. Cell. 2020 10 29; 183(3):739-751.e8.
    View in: PubMed
    Score: 0.028
  10. Wang Y, Lifshitz L, Gellatly K, Vinton CL, Busman-Sahay K, McCauley S, Vangala P, Kim K, Derr A, Jaiswal S, Kucukural A, McDonel P, Hunt PW, Greenough T, Houghton J, Somsouk M, Estes JD, Brenchley JM, Garber M, Deeks SG, Luban J. HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells. Nat Immunol. 2020 03; 21(3):274-286.
    View in: PubMed
    Score: 0.027
  11. Kim K, Dauphin A, Komurlu S, McCauley SM, Yurkovetskiy L, Carbone C, Diehl WE, Strambio-De-Castillia C, Campbell EM, Luban J. Cyclophilin A protects HIV-1 from restriction by human TRIM5a. Nat Microbiol. 2019 12; 4(12):2044-2051.
    View in: PubMed
    Score: 0.026
  12. Luban J. The hidden cost of genetic resistance to HIV-1. Nat Med. 2019 06; 25(6):878-879.
    View in: PubMed
    Score: 0.025
  13. McCauley SM, Kim K, Nowosielska A, Dauphin A, Yurkovetskiy L, Diehl WE, Luban J. Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines. Nat Commun. 2018 12 13; 9(1):5305.
    View in: PubMed
    Score: 0.024
  14. Yurkovetskiy L, Guney MH, Kim K, Goh SL, McCauley S, Dauphin A, Diehl WE, Luban J. Primate immunodeficiency virus proteins Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex. Nat Microbiol. 2018 12; 3(12):1354-1361.
    View in: PubMed
    Score: 0.024
  15. Diehl WE, Lin AE, Grubaugh ND, Carvalho LM, Kim K, Kyawe PP, McCauley SM, Donnard E, Kucukural A, McDonel P, Schaffner SF, Garber M, Rambaut A, Andersen KG, Sabeti PC, Luban J. Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013-2016 Epidemic. Cell. 2016 11 03; 167(4):1088-1098.e6.
    View in: PubMed
    Score: 0.021
  16. Lascano J, Uchil PD, Mothes W, Luban J. TRIM5 Retroviral Restriction Activity Correlates with the Ability To Induce Innate Immune Signaling. J Virol. 2016 01 01; 90(1):308-16.
    View in: PubMed
    Score: 0.020
  17. Pizzato M, McCauley SM, Neagu MR, Pertel T, Firrito C, Ziglio S, Dauphin A, Zufferey M, Berthoux L, Luban J. Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration. PLoS Pathog. 2015 Jul; 11(7):e1005050.
    View in: PubMed
    Score: 0.019
  18. Bartels H, Luban J. Gammaretroviral pol sequences act in cis to direct polysome loading and NXF1/NXT-dependent protein production by gag-encoded RNA. Retrovirology. 2014 Sep 12; 11:73.
    View in: PubMed
    Score: 0.018
  19. Reinhard C, Bottinelli D, Kim B, Luban J. Vpx rescue of HIV-1 from the antiviral state in mature dendritic cells is independent of the intracellular deoxynucleotide concentration. Retrovirology. 2014 Feb 01; 11:12.
    View in: PubMed
    Score: 0.017
  20. De Iaco A, Luban J. Cyclophilin A promotes HIV-1 reverse transcription but its effect on transduction correlates best with its effect on nuclear entry of viral cDNA. Retrovirology. 2014 Jan 30; 11:11.
    View in: PubMed
    Score: 0.017
  21. De Iaco A, Santoni F, Vannier A, Guipponi M, Antonarakis S, Luban J. TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm. Retrovirology. 2013 Feb 15; 10:20.
    View in: PubMed
    Score: 0.016
  22. Santoni FA, Guerra J, Luban J. HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency. Retrovirology. 2012 Dec 20; 9:111.
    View in: PubMed
    Score: 0.016
  23. Luban J. More than one way to TRIM a capsid. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19517-8.
    View in: PubMed
    Score: 0.016
  24. Gr?tter MG, Luban J. TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling. Curr Opin Virol. 2012 Apr; 2(2):142-50.
    View in: PubMed
    Score: 0.015
  25. De Iaco A, Luban J. Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus. Retrovirology. 2011 Dec 06; 8:98.
    View in: PubMed
    Score: 0.015
  26. Pertel T, Reinhard C, Luban J. Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon. Retrovirology. 2011 Jun 22; 8:49.
    View in: PubMed
    Score: 0.015
  27. Pertel T, Hausmann S, Morger D, Z?ger S, Guerra J, Lascano J, Reinhard C, Santoni FA, Uchil PD, Chatel L, Bisiaux A, Albert ML, Strambio-De-Castillia C, Mothes W, Pizzato M, Gr?tter MG, Luban J. TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature. 2011 Apr 21; 472(7343):361-5.
    View in: PubMed
    Score: 0.014
  28. Santoni FA, Hartley O, Luban J. Deciphering the code for retroviral integration target site selection. PLoS Comput Biol. 2010 Nov 24; 6(11):e1001008.
    View in: PubMed
    Score: 0.014
  29. Sokolskaja E, Olivari S, Zufferey M, Strambio-De-Castillia C, Pizzato M, Luban J. Cyclosporine blocks incorporation of HIV-1 envelope glycoprotein into virions. J Virol. 2010 May; 84(9):4851-5.
    View in: PubMed
    Score: 0.013
  30. Neagu MR, Ziegler P, Pertel T, Strambio-De-Castillia C, Gr?tter C, Martinetti G, Mazzucchelli L, Gr?tter M, Manz MG, Luban J. Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components. J Clin Invest. 2009 Oct; 119(10):3035-47.
    View in: PubMed
    Score: 0.013
  31. Sebastian S, Gr?tter C, Strambio de Castillia C, Pertel T, Olivari S, Gr?tter MG, Luban J. An invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding. J Virol. 2009 Apr; 83(7):3365-73.
    View in: PubMed
    Score: 0.012
  32. Berthoux L, Sebastian S, Muesing MA, Luban J. The role of lysine 186 in HIV-1 integrase multimerization. Virology. 2007 Jul 20; 364(1):227-36.
    View in: PubMed
    Score: 0.011
  33. Luban J. Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infection. J Virol. 2007 Feb; 81(3):1054-61.
    View in: PubMed
    Score: 0.010
  34. Sokolskaja E, Luban J. Cyclophilin, TRIM5, and innate immunity to HIV-1. Curr Opin Microbiol. 2006 Aug; 9(4):404-8.
    View in: PubMed
    Score: 0.010
  35. Sokolskaja E, Berthoux L, Luban J. Cyclophilin A and TRIM5alpha independently regulate human immunodeficiency virus type 1 infectivity in human cells. J Virol. 2006 Mar; 80(6):2855-62.
    View in: PubMed
    Score: 0.010
  36. Sebastian S, Sokolskaja E, Luban J. Arsenic counteracts human immunodeficiency virus type 1 restriction by various TRIM5 orthologues in a cell type-dependent manner. J Virol. 2006 Feb; 80(4):2051-4.
    View in: PubMed
    Score: 0.010
  37. Berthoux L, Sebastian S, Sayah DM, Luban J. Disruption of human TRIM5alpha antiviral activity by nonhuman primate orthologues. J Virol. 2005 Jun; 79(12):7883-8.
    View in: PubMed
    Score: 0.010
  38. Gurer C, H?glund A, H?glund S, Luban J. ATPgammaS disrupts human immunodeficiency virus type 1 virion core integrity. J Virol. 2005 May; 79(9):5557-67.
    View in: PubMed
    Score: 0.010
  39. Gurer C, Berthoux L, Luban J. Covalent modification of human immunodeficiency virus type 1 p6 by SUMO-1. J Virol. 2005 Jan; 79(2):910-7.
    View in: PubMed
    Score: 0.009
  40. Sokolskaja E, Sayah DM, Luban J. Target cell cyclophilin A modulates human immunodeficiency virus type 1 infectivity. J Virol. 2004 Dec; 78(23):12800-8.
    View in: PubMed
    Score: 0.009
  41. Berthoux L, Sebastian S, Sokolskaja E, Luban J. Lv1 inhibition of human immunodeficiency virus type 1 is counteracted by factors that stimulate synthesis or nuclear translocation of viral cDNA. J Virol. 2004 Nov; 78(21):11739-50.
    View in: PubMed
    Score: 0.009
  42. Sayah DM, Luban J. Selection for loss of Ref1 activity in human cells releases human immunodeficiency virus type 1 from cyclophilin A dependence during infection. J Virol. 2004 Nov; 78(21):12066-70.
    View in: PubMed
    Score: 0.009
  43. Padron A, Dwivedi R, Chakraborty R, Prakash P, Kim K, Shi J, Ahn J, Pandhare J, Luban J, Aiken C, Balasubramaniam M, Dash C. Cyclophilin A facilitates HIV-1 integration. J Virol. 2024 Nov 19; 98(11):e0094724.
    View in: PubMed
    Score: 0.009
  44. Sayah DM, Sokolskaja E, Berthoux L, Luban J. Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1. Nature. 2004 Jul 29; 430(6999):569-73.
    View in: PubMed
    Score: 0.009
  45. Chang F, Re F, Sebastian S, Sazer S, Luban J. HIV-1 Vpr induces defects in mitosis, cytokinesis, nuclear structure, and centrosomes. Mol Biol Cell. 2004 Apr; 15(4):1793-801.
    View in: PubMed
    Score: 0.009
  46. Jain A, Govindan R, Berkman AR, Luban J, D?az-Salinas MA, Durham ND, Munro JB. Regulation of Ebola GP conformation and membrane binding by the chemical environment of the late endosome. PLoS Pathog. 2023 Dec; 19(12):e1011848.
    View in: PubMed
    Score: 0.009
  47. Padron A, Prakash P, Pandhare J, Luban J, Aiken C, Balasubramaniam M, Dash C. Emerging role of cyclophilin A in HIV-1 infection: from producer cell to the target cell nucleus. J Virol. 2023 11 30; 97(11):e0073223.
    View in: PubMed
    Score: 0.009
  48. Ponnienselvan K, Liu P, Nyalile T, Oikemus S, Maitland SA, Lawson ND, Luban J, Wolfe SA. Reducing the inherent auto-inhibitory interaction within the pegRNA enhances prime editing efficiency. Nucleic Acids Res. 2023 07 21; 51(13):6966-6980.
    View in: PubMed
    Score: 0.008
  49. Xue G, Yu HJ, Buffone C, Huang SW, Lee K, Goh SL, Gres AT, Guney MH, Sarafianos SG, Luban J, Diaz-Griffero F, KewalRamani VN. The HIV-1 capsid core is an opportunistic nuclear import receptor. Nat Commun. 2023 06 24; 14(1):3782.
    View in: PubMed
    Score: 0.008
  50. Egri SB, Wang X, D?az-Salinas MA, Luban J, Dudkina NV, Munro JB, Shen K. Detergent modulates the conformational equilibrium of SARS-CoV-2 Spike during cryo-EM structural determination. Nat Commun. 2023 05 03; 14(1):2527.
    View in: PubMed
    Score: 0.008
  51. Berthoux L, Towers GJ, Gurer C, Salomoni P, Pandolfi PP, Luban J. As(2)O(3) enhances retroviral reverse transcription and counteracts Ref1 antiviral activity. J Virol. 2003 Mar; 77(5):3167-80.
    View in: PubMed
    Score: 0.008
  52. Adams G, Moreno GK, Petros BA, Uddin R, Levine Z, Kotzen B, Messer KS, Dobbins ST, DeRuff KC, Loreth CM, Brock-Fisher T, Schaffner SF, Chaluvadi S, Kanjilal S, Luban J, Ozonoff A, Park DJ, Turbett SE, Siddle KJ, MacInnis BL, Sabeti PC, Lemieux JE. Viral Lineages in the 2022 RSV Surge in the United States. N Engl J Med. 2023 Apr 06; 388(14):1335-1337.
    View in: PubMed
    Score: 0.008
  53. Odongo L, Zadrozny KK, Diehl WE, Luban J, White JM, Ganser-Pornillos BK, Tamm LK, Pornillos O. Purification and structure of luminal domain C of human Niemann-Pick C1 protein. Acta Crystallogr F Struct Biol Commun. 2023 Feb 01; 79(Pt 2):45-50.
    View in: PubMed
    Score: 0.008
  54. Seaman MS, Siedner MJ, Boucau J, Lavine CL, Ghantous F, Liew MY, Mathews JI, Singh A, Marino C, Regan J, Uddin R, Choudhary MC, Flynn JP, Chen G, Stuckwisch AM, Lipiner T, Kittilson A, Melberg M, Gilbert RF, Reynolds Z, Iyer SL, Chamberlin GC, Vyas TD, Vyas JM, Goldberg MB, Luban J, Li JZ, Barczak AK, Lemieux JE. Vaccine breakthrough infection leads to distinct profiles of neutralizing antibody responses by SARS-CoV-2 variant. JCI Insight. 2022 10 10; 7(19).
    View in: PubMed
    Score: 0.008
  55. Petros BA, Paull JS, Tomkins-Tinch CH, Loftness BC, DeRuff KC, Nair P, Gionet GL, Benz A, Brock-Fisher T, Hughes M, Yurkovetskiy L, Mulaudzi S, Leenerman E, Nyalile T, Moreno GK, Specht I, Sani K, Adams G, Babet SV, Baron E, Blank JT, Boehm C, Botti-Lodovico Y, Brown J, Buisker AR, Burcham T, Chylek L, Cronan P, Dauphin A, Desreumaux V, Doss M, Flynn B, Gladden-Young A, Glennon O, Harmon HD, Hook TV, Kary A, King C, Loreth C, Marrs L, McQuade KJ, Milton TT, Mulford JM, Oba K, Pearlman L, Schifferli M, Schmidt MJ, Tandus GM, Tyler A, Vodzak ME, Krohn Bevill K, Colubri A, MacInnis BL, Ozsoy AZ, Parrie E, Sholtes K, Siddle KJ, Fry B, Luban J, Park DJ, Marshall J, Bronson A, Schaffner SF, Sabeti PC. Multimodal surveillance of SARS-CoV-2 at a university enables development of a robust outbreak response framework. Med. 2022 Dec 09; 3(12):883-900.e13.
    View in: PubMed
    Score: 0.008
  56. Obermeyer F, Jankowiak M, Barkas N, Schaffner SF, Pyle JD, Yurkovetskiy L, Bosso M, Park DJ, Babadi M, MacInnis BL, Luban J, Sabeti PC, Lemieux JE. Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness. Science. 2022 06 17; 376(6599):1327-1332.
    View in: PubMed
    Score: 0.008
  57. Gurer C, Cimarelli A, Luban J. Specific incorporation of heat shock protein 70 family members into primate lentiviral virions. J Virol. 2002 May; 76(9):4666-70.
    View in: PubMed
    Score: 0.008
  58. D?az-Salinas MA, Li Q, Ejemel M, Yurkovetskiy L, Luban J, Shen K, Wang Y, Munro JB. Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike. Elife. 2022 03 24; 11.
    View in: PubMed
    Score: 0.008
  59. Griesemer D, Xue JR, Reilly SK, Ulirsch JC, Kukreja K, Davis JR, Kanai M, Yang DK, Butts JC, Guney MH, Luban J, Montgomery SB, Finucane HK, Novina CD, Tewhey R, Sabeti PC. Genome-wide functional screen of 3'UTR variants uncovers causal variants for human disease and evolution. Cell. 2021 09 30; 184(20):5247-5260.e19.
    View in: PubMed
    Score: 0.007
  60. Cimarelli A, Luban J. Context-dependent phenotype of a human immunodeficiency virus type 1 nucleocapsid mutation. J Virol. 2001 Aug; 75(15):7193-7.
    View in: PubMed
    Score: 0.007
  61. Fukuda K, Okamura K, Riding RL, Fan X, Afshari K, Haddadi NS, McCauley SM, Guney MH, Luban J, Funakoshi T, Yaguchi T, Kawakami Y, Khvorova A, Fitzgerald KA, Harris JE. AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma. J Exp Med. 2021 09 06; 218(9).
    View in: PubMed
    Score: 0.007
  62. Lechner K, Mott S, Al-Saifi R, Knipfer L, Wirtz S, Atreya R, Vieth M, Rath T, Fraass T, Winter Z, August A, Luban J, Zimmermann VS, Weigmann B, Neurath MF. Targeting of the Tec Kinase ITK Drives Resolution of T Cell-Mediated Colitis and Emerges as Potential Therapeutic Option in Ulcerative Colitis. Gastroenterology. 2021 10; 161(4):1270-1287.e19.
    View in: PubMed
    Score: 0.007
  63. Tomkins-Tinch CH, Daly JS, Gladden-Young A, Theodoropoulos NM, Madaio MP, Yu N, Vanguri VK, Siddle KJ, Adams G, Krasilnikova LA, Movahedi B, Bozorgzadeh A, Simin K, Lemieux JE, Luban J, Park DJ, MacInnis BL, Sabeti PC, Levitz SM. SARS-CoV-2 Reinfection in a Liver Transplant Recipient. Ann Intern Med. 2021 08; 174(8):1178-1180.
    View in: PubMed
    Score: 0.007
  64. Braaten D, Luban J. Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells. EMBO J. 2001 Mar 15; 20(6):1300-9.
    View in: PubMed
    Score: 0.007
  65. Lemieux JE, Siddle KJ, Shaw BM, Loreth C, Schaffner SF, Gladden-Young A, Adams G, Fink T, Tomkins-Tinch CH, Krasilnikova LA, DeRuff KC, Rudy M, Bauer MR, Lagerborg KA, Normandin E, Chapman SB, Reilly SK, Anahtar MN, Lin AE, Carter A, Myhrvold C, Kemball ME, Chaluvadi S, Cusick C, Flowers K, Neumann A, Cerrato F, Farhat M, Slater D, Harris JB, Branda JA, Hooper D, Gaeta JM, Baggett TP, O'Connell J, Gnirke A, Lieberman TD, Philippakis A, Burns M, Brown CM, Luban J, Ryan ET, Turbett SE, LaRocque RC, Hanage WP, Gallagher GR, Madoff LC, Smole S, Pierce VM, Rosenberg E, Sabeti PC, Park DJ, MacInnis BL. Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events. Science. 2021 02 05; 371(6529).
    View in: PubMed
    Score: 0.007
  66. Cimarelli A, Luban J. Human immunodeficiency virus type 1 virion density is not determined by nucleocapsid basic residues. J Virol. 2000 Aug; 74(15):6734-40.
    View in: PubMed
    Score: 0.007
  67. Cimarelli A, Sandin S, H?glund S, Luban J. Rescue of multiple viral functions by a second-site suppressor of a human immunodeficiency virus type 1 nucleocapsid mutation. J Virol. 2000 May; 74(9):4273-83.
    View in: PubMed
    Score: 0.007
  68. Ohainle M, Kim K, Komurlu Keceli S, Felton A, Campbell E, Luban J, Emerman M. TRIM34 restricts HIV-1 and SIV capsids in a TRIM5a-dependent manner. PLoS Pathog. 2020 04; 16(4):e1008507.
    View in: PubMed
    Score: 0.007
  69. Cimarelli A, Sandin S, H?glund S, Luban J. Basic residues in human immunodeficiency virus type 1 nucleocapsid promote virion assembly via interaction with RNA. J Virol. 2000 Apr; 74(7):3046-57.
    View in: PubMed
    Score: 0.007
  70. Das DK, Bulow U, Diehl WE, Durham ND, Senjobe F, Chandran K, Luban J, Munro JB. Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca2+, and receptor binding. PLoS Biol. 2020 02; 18(2):e3000626.
    View in: PubMed
    Score: 0.007
  71. Durham ND, Howard AR, Govindan R, Senjobe F, Fels JM, Diehl WE, Luban J, Chandran K, Munro JB. Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics. Viruses. 2020 01 15; 12(1).
    View in: PubMed
    Score: 0.007
  72. Lin AE, Diehl WE, Cai Y, Finch CL, Akusobi C, Kirchdoerfer RN, Bollinger L, Schaffner SF, Brown EA, Saphire EO, Andersen KG, Kuhn JH, Luban J, Sabeti PC. Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111. Viruses. 2020 01 15; 12(1).
    View in: PubMed
    Score: 0.007
  73. Burniston MT, Cimarelli A, Colgan J, Curtis SP, Luban J. Human immunodeficiency virus type 1 Gag polyprotein multimerization requires the nucleocapsid domain and RNA and is promoted by the capsid-dimer interface and the basic region of matrix protein. J Virol. 1999 Oct; 73(10):8527-40.
    View in: PubMed
    Score: 0.006
  74. Cimarelli A, Luban J. Translation elongation factor 1-alpha interacts specifically with the human immunodeficiency virus type 1 Gag polyprotein. J Virol. 1999 Jul; 73(7):5388-401.
    View in: PubMed
    Score: 0.006
  75. Chiramel AI, Meyerson NR, McNally KL, Broeckel RM, Montoya VR, M?ndez-Sol?s O, Robertson SJ, Sturdevant GL, Lubick KJ, Nair V, Youseff BH, Ireland RM, Bosio CM, Kim K, Luban J, Hirsch VM, Taylor RT, Bouamr F, Sawyer SL, Best SM. TRIM5a Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation. Cell Rep. 2019 06 11; 27(11):3269-3283.e6.
    View in: PubMed
    Score: 0.006
  76. Liu P, Luk K, Shin M, Idrizi F, Kwok S, Roscoe B, Mintzer E, Suresh S, Morrison K, Fraz?o JB, Bolukbasi MF, Ponnienselvan K, Luban J, Zhu LJ, Lawson ND, Wolfe SA. Enhanced Cas12a editing in mammalian cells and zebrafish. Nucleic Acids Res. 2019 May 07; 47(8):4169-4180.
    View in: PubMed
    Score: 0.006
  77. Gawron MA, Duval M, Carbone C, Jaiswal S, Wallace A, Martin JC, Dauphin A, Brehm MA, Greiner DL, Shultz LD, Luban J, Cavacini LA. Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1. J Immunol. 2019 02 01; 202(3):799-804.
    View in: PubMed
    Score: 0.006
  78. Yin L, Braaten D, Luban J. Human immunodeficiency virus type 1 replication is modulated by host cyclophilin A expression levels. J Virol. 1998 Aug; 72(8):6430-6.
    View in: PubMed
    Score: 0.006
  79. Donnard E, Vangala P, Afik S, McCauley S, Nowosielska A, Kucukural A, Tabak B, Zhu X, Diehl W, McDonel P, Yosef N, Luban J, Garber M. Comparative Analysis of Immune Cells Reveals a Conserved Regulatory Lexicon. Cell Syst. 2018 Mar 28; 6(3):381-394.e7.
    View in: PubMed
    Score: 0.006
  80. Morger D, Zosel F, B?hlmann M, Z?ger S, Mittelviefhaus M, Schuler B, Luban J, Gr?tter MG. The Three-Fold Axis of the HIV-1 Capsid Lattice Is the Species-Specific Binding Interface for TRIM5a. J Virol. 2018 03 01; 92(5).
    View in: PubMed
    Score: 0.006
  81. Quitadamo B, Peters PJ, Repik A, O'Connell O, Mou Z, Koch M, Somasundaran M, Brody R, Luzuriaga K, Wallace A, Wang S, Lu S, McCauley S, Luban J, Duenas-Decamp M, Gonzalez-Perez MP, Clapham PR. HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded. J Virol. 2018 01 15; 92(2).
    View in: PubMed
    Score: 0.006
  82. Alghanem B, Nikitin F, Stricker T, Duchoslav E, Luban J, Strambio-De-Castillia C, Muller M, Lisacek F, Varesio E, Hopfgartner G. Optimization by infusion of multiple reaction monitoring transitions for sensitive quantification of peptides by liquid chromatography/mass spectrometry. Rapid Commun Mass Spectrom. 2017 May 15; 31(9):753-761.
    View in: PubMed
    Score: 0.005
  83. Braaten D, Ansari H, Luban J. The hydrophobic pocket of cyclophilin is the binding site for the human immunodeficiency virus type 1 Gag polyprotein. J Virol. 1997 Mar; 71(3):2107-13.
    View in: PubMed
    Score: 0.005
  84. Re F, Luban J. HIV-1 Vpr: G2 cell cycle arrest, macrophages and nuclear transport. Prog Cell Cycle Res. 1997; 3:21-7.
    View in: PubMed
    Score: 0.005
  85. Braaten D, Aberham C, Franke EK, Yin L, Phares W, Luban J. Cyclosporine A-resistant human immunodeficiency virus type 1 mutants demonstrate that Gag encodes the functional target of cyclophilin A. J Virol. 1996 Aug; 70(8):5170-6.
    View in: PubMed
    Score: 0.005
  86. Franke EK, Luban J. Inhibition of HIV-1 replication by cyclosporine A or related compounds correlates with the ability to disrupt the Gag-cyclophilin A interaction. Virology. 1996 Aug 01; 222(1):279-82.
    View in: PubMed
    Score: 0.005
  87. Braaten D, Franke EK, Luban J. Cyclophilin A is required for the replication of group M human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus SIV(CPZ)GAB but not group O HIV-1 or other primate immunodeficiency viruses. J Virol. 1996 Jul; 70(7):4220-7.
    View in: PubMed
    Score: 0.005
  88. Colgan J, Yuan HE, Franke EK, Luban J. Binding of the human immunodeficiency virus type 1 Gag polyprotein to cyclophilin A is mediated by the central region of capsid and requires Gag dimerization. J Virol. 1996 Jul; 70(7):4299-310.
    View in: PubMed
    Score: 0.005
  89. Braaten D, Franke EK, Luban J. Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription. J Virol. 1996 Jun; 70(6):3551-60.
    View in: PubMed
    Score: 0.005
  90. Chen NY, Zhou L, Gane PJ, Opp S, Ball NJ, Nicastro G, Zufferey M, Buffone C, Luban J, Selwood D, Diaz-Griffero F, Taylor I, Fassati A. HIV-1 capsid is involved in post-nuclear entry steps. Retrovirology. 2016 Apr 23; 13:28.
    View in: PubMed
    Score: 0.005
  91. Braaten D, Wellington S, Warburton D, Luban J. Assignment of cyclophilin A (PPIA) to human chromosome band 7p13by in situ hybridization. Cytogenet Cell Genet. 1996; 74(4):262.
    View in: PubMed
    Score: 0.005
  92. Re F, Braaten D, Franke EK, Luban J. Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B. J Virol. 1995 Nov; 69(11):6859-64.
    View in: PubMed
    Score: 0.005
  93. Bilbao A, Zhang Y, Varesio E, Luban J, Strambio-De-Castillia C, Lisacek F, Hopfgartner G. Ranking Fragment Ions Based on Outlier Detection for Improved Label-Free Quantification in Data-Independent Acquisition LC-MS/MS. J Proteome Res. 2015 Nov 06; 14(11):4581-93.
    View in: PubMed
    Score: 0.005
  94. Rosa A, Chande A, Ziglio S, De Sanctis V, Bertorelli R, Goh SL, McCauley SM, Nowosielska A, Antonarakis SE, Luban J, Santoni FA, Pizzato M. HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation. Nature. 2015 Oct 08; 526(7572):212-7.
    View in: PubMed
    Score: 0.005
  95. Zhang Y, Bilbao A, Bruderer T, Luban J, Strambio-De-Castillia C, Lisacek F, Hopfgartner G, Varesio E. The Use of Variable Q1 Isolation Windows Improves Selectivity in LC-SWATH-MS Acquisition. J Proteome Res. 2015 Oct 02; 14(10):4359-71.
    View in: PubMed
    Score: 0.005
  96. Zhang Y, Bottinelli D, Lisacek F, Luban J, Strambio-De-Castillia C, Varesio E, Hopfgartner G. Optimization of human dendritic cell sample preparation for mass spectrometry-based proteomic studies. Anal Biochem. 2015 Sep 01; 484:40-50.
    View in: PubMed
    Score: 0.005
  97. Franke EK, Luban J. Cyclophilin and gag in HIV-1 replication and pathogenesis. Adv Exp Med Biol. 1995; 374:217-28.
    View in: PubMed
    Score: 0.005
  98. Franke EK, Yuan HE, Luban J. Specific incorporation of cyclophilin A into HIV-1 virions. Nature. 1994 Nov 24; 372(6504):359-62.
    View in: PubMed
    Score: 0.005
  99. Franke EK, Yuan HE, Bossolt KL, Goff SP, Luban J. Specificity and sequence requirements for interactions between various retroviral Gag proteins. J Virol. 1994 Aug; 68(8):5300-5.
    View in: PubMed
    Score: 0.005
  100. Luban J, Goff SP. Mutational analysis of cis-acting packaging signals in human immunodeficiency virus type 1 RNA. J Virol. 1994 Jun; 68(6):3784-93.
    View in: PubMed
    Score: 0.004
  101. Singh R, Patel V, Mureithi MW, Naranbhai V, Ramsuran D, Tulsi S, Hiramen K, Werner L, Mlisana K, Altfeld M, Luban J, Kasprowicz V, Dheda K, Abdool Karim SS, Ndung'u T. TRIM5a and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment. J Virol. 2014 Apr; 88(8):4291-303.
    View in: PubMed
    Score: 0.004
  102. Yang Y, Luban J, Diaz-Griffero F. The fate of HIV-1 capsid: a biochemical assay for HIV-1 uncoating. Methods Mol Biol. 2014; 1087:29-36.
    View in: PubMed
    Score: 0.004
  103. Brehm MA, Shultz LD, Luban J, Greiner DL. Overcoming current limitations in humanized mouse research. J Infect Dis. 2013 Nov; 208 Suppl 2:S125-30.
    View in: PubMed
    Score: 0.004
  104. Xu H, Franks T, Gibson G, Huber K, Rahm N, Strambio De Castillia C, Luban J, Aiken C, Watkins S, Sluis-Cremer N, Ambrose Z. Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay. Retrovirology. 2013 Jul 09; 10:70.
    View in: PubMed
    Score: 0.004
  105. Luban J, Bossolt KL, Franke EK, Kalpana GV, Goff SP. Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B. Cell. 1993 Jun 18; 73(6):1067-78.
    View in: PubMed
    Score: 0.004
  106. Miyamoto T, Nakayama EE, Yokoyama M, Ibe S, Takehara S, Kono K, Yokomaku Y, Pizzato M, Luban J, Sugiura W, Sato H, Shioda T. The carboxyl-terminus of human immunodeficiency virus type 2 circulating recombinant form 01_AB capsid protein affects sensitivity to human TRIM5a. PLoS One. 2012; 7(10):e47757.
    View in: PubMed
    Score: 0.004
  107. Uchil PD, Hinz A, Siegel S, Coenen-Stass A, Pertel T, Luban J, Mothes W. TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity. J Virol. 2013 Jan; 87(1):257-72.
    View in: PubMed
    Score: 0.004
  108. Lai RP, Yan J, Heeney J, McClure MO, G?ttlinger H, Luban J, Pizzato M. Nef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41. PLoS Pathog. 2011 Dec; 7(12):e1002442.
    View in: PubMed
    Score: 0.004
  109. Lukic Z, Hausmann S, Sebastian S, Rucci J, Sastri J, Robia SL, Luban J, Campbell EM. TRIM5a associates with proteasomal subunits in cells while in complex with HIV-1 virions. Retrovirology. 2011 Nov 12; 8:93.
    View in: PubMed
    Score: 0.004
  110. Kajaste-Rudnitski A, Marelli SS, Pultrone C, Pertel T, Uchil PD, Mechti N, Mothes W, Poli G, Luban J, Vicenzi E. TRIM22 inhibits HIV-1 transcription independently of its E3 ubiquitin ligase activity, Tat, and NF-kappaB-responsive long terminal repeat elements. J Virol. 2011 May; 85(10):5183-96.
    View in: PubMed
    Score: 0.004
  111. Su?? G, Sarr? E, Puigmul? M, L?pez-Hell?n J, Zufferey M, Pertel T, Luban J, Meseguer A. Cyclophilin B interacts with sodium-potassium ATPase and is required for pump activity in proximal tubule cells of the kidney. PLoS One. 2010 Nov 10; 5(11):e13930.
    View in: PubMed
    Score: 0.003
  112. Singh R, Gaiha G, Werner L, McKim K, Mlisana K, Luban J, Walker BD, Karim SS, Brass AL, Ndung'u T. Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection. J Virol. 2011 Jan; 85(1):208-16.
    View in: PubMed
    Score: 0.003
  113. Bernasconi R, Sold? T, Galli C, Pertel T, Luban J, Molinari M. Cyclosporine A-sensitive, cyclophilin B-dependent endoplasmic reticulum-associated degradation. PLoS One. 2010 Sep 28; 5(9).
    View in: PubMed
    Score: 0.003
  114. O'Connor C, Pertel T, Gray S, Robia SL, Bakowska JC, Luban J, Campbell EM. p62/sequestosome-1 associates with and sustains the expression of retroviral restriction factor TRIM5alpha. J Virol. 2010 Jun; 84(12):5997-6006.
    View in: PubMed
    Score: 0.003
  115. van Anken E, Pena F, Hafkemeijer N, Christis C, Romijn EP, Grauschopf U, Oorschot VM, Pertel T, Engels S, Ora A, L?stun V, Glockshuber R, Klumperman J, Heck AJ, Luban J, Braakman I. Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1. Proc Natl Acad Sci U S A. 2009 Oct 06; 106(40):17019-24.
    View in: PubMed
    Score: 0.003
  116. Strebel K, Luban J, Jeang KT. Human cellular restriction factors that target HIV-1 replication. BMC Med. 2009 Sep 16; 7:48.
    View in: PubMed
    Score: 0.003
  117. Mangeat B, Gers-Huber G, Lehmann M, Zufferey M, Luban J, Piguet V. HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation. PLoS Pathog. 2009 Sep; 5(9):e1000574.
    View in: PubMed
    Score: 0.003
  118. Kaul A, Stauffer S, Berger C, Pertel T, Schmitt J, Kallis S, Zayas M, Lopez MZ, Lohmann V, Luban J, Bartenschlager R. Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics. PLoS Pathog. 2009 Aug; 5(8):e1000546.
    View in: PubMed
    Score: 0.003
  119. Marq JB, Hausmann S, Luban J, Kolakofsky D, Garcin D. The double-stranded RNA binding domain of the vaccinia virus E3L protein inhibits both RNA- and DNA-induced activation of interferon beta. J Biol Chem. 2009 Sep 18; 284(38):25471-8.
    View in: PubMed
    Score: 0.003
  120. Goujon C, Arfi V, Pertel T, Luban J, Lienard J, Rigal D, Darlix JL, Cimarelli A. Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells. J Virol. 2008 Dec; 82(24):12335-45.
    View in: PubMed
    Score: 0.003
  121. Santoni de Sio FR, Gritti A, Cascio P, Neri M, Sampaolesi M, Galli C, Luban J, Naldini L. Lentiviral vector gene transfer is limited by the proteasome at postentry steps in various types of stem cells. Stem Cells. 2008 Aug; 26(8):2142-52.
    View in: PubMed
    Score: 0.003
  122. Bernasconi R, Pertel T, Luban J, Molinari M. A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal. J Biol Chem. 2008 Jun 13; 283(24):16446-54.
    View in: PubMed
    Score: 0.003
  123. Takeuchi H, Buckler-White A, Goila-Gaur R, Miyagi E, Khan MA, Opi S, Kao S, Sokolskaja E, Pertel T, Luban J, Strebel K. Vif counteracts a cyclophilin A-imposed inhibition of simian immunodeficiency viruses in human cells. J Virol. 2007 Aug; 81(15):8080-90.
    View in: PubMed
    Score: 0.003
  124. Zhang S, Joseph G, Pollok K, Berthoux L, Sastry L, Luban J, Cornetta K. G2 cell cycle arrest and cyclophilin A in lentiviral gene transfer. Mol Ther. 2006 Oct; 14(4):546-54.
    View in: PubMed
    Score: 0.003
  125. Bisikirska B, Colgan J, Luban J, Bluestone JA, Herold KC. TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs. J Clin Invest. 2005 Oct; 115(10):2904-13.
    View in: PubMed
    Score: 0.002
  126. Cand? C, Vahsen N, Kouranti I, Schmitt E, Daugas E, Spahr C, Luban J, Kroemer RT, Giordanetto F, Garrido C, Penninger JM, Kroemer G. AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis. Oncogene. 2004 Feb 26; 23(8):1514-21.
    View in: PubMed
    Score: 0.002
  127. Towers GJ, Hatziioannou T, Cowan S, Goff SP, Luban J, Bieniasz PD. Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors. Nat Med. 2003 Sep; 9(9):1138-43.
    View in: PubMed
    Score: 0.002
  128. Zander K, Sherman MP, Tessmer U, Bruns K, Wray V, Prechtel AT, Schubert E, Henklein P, Luban J, Neidleman J, Greene WC, Schubert U. Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression. J Biol Chem. 2003 Oct 31; 278(44):43202-13.
    View in: PubMed
    Score: 0.002
  129. Zhang YJ, Hatziioannou T, Zang T, Braaten D, Luban J, Goff SP, Bieniasz PD. Envelope-dependent, cyclophilin-independent effects of glycosaminoglycans on human immunodeficiency virus type 1 attachment and infection. J Virol. 2002 Jun; 76(12):6332-43.
    View in: PubMed
    Score: 0.002
  130. Reicin AS, Paik S, Berkowitz RD, Luban J, Lowy I, Goff SP. Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity. J Virol. 1995 Feb; 69(2):642-50.
    View in: PubMed
    Score: 0.001
  131. Dunaief JL, Strober BE, Guha S, Khavari PA, Alin K, Luban J, Begemann M, Crabtree GR, Goff SP. The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell. 1994 Oct 07; 79(1):119-30.
    View in: PubMed
    Score: 0.001
  132. Dorfman T, Luban J, Goff SP, Haseltine WA, G?ttlinger HG. Mapping of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein. J Virol. 1993 Oct; 67(10):6159-69.
    View in: PubMed
    Score: 0.001
  133. Van Voorhis WC, Steinman RM, Hair LS, Luban J, Witmer MD, Koide S, Cohn ZA. Specific antimononuclear phagocyte monoclonal antibodies. Application to the purification of dendritic cells and the tissue localization of macrophages. J Exp Med. 1983 Jul 01; 158(1):126-45.
    View in: PubMed
    Score: 0.001
  134. Van Voorhis WC, Valinsky J, Hoffman E, Luban J, Hair LS, Steinman RM. Relative efficacy of human monocytes and dendritic cells as accessory cells for T cell replication. J Exp Med. 1983 Jul 01; 158(1):174-91.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.