Katherine Fitzgerald to Inflammation
This is a "connection" page, showing publications Katherine Fitzgerald has written about Inflammation.
Connection Strength
6.222
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Dong M, Fitzgerald KA. DNA-sensing pathways in health, autoinflammatory and autoimmune diseases. Nat Immunol. 2024 Nov; 25(11):2001-2014.
Score: 0.530
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Gao KM, Fitzgerald KA. ERADication of STING limits inflammation. Nat Cell Biol. 2023 05; 25(5):635-636.
Score: 0.480
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Orning P, Lien E, Fitzgerald KA. Gasdermins and their role in immunity and inflammation. J Exp Med. 2019 11 04; 216(11):2453-2465.
Score: 0.374
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Atianand MK, Hu W, Satpathy AT, Shen Y, Ricci EP, Alvarez-Dominguez JR, Bhatta A, Schattgen SA, McGowan JD, Blin J, Braun JE, Gandhi P, Moore MJ, Chang HY, Lodish HF, Caffrey DR, Fitzgerald KA. A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation. Cell. 2016 Jun 16; 165(7):1672-1685.
Score: 0.298
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Elling R, Chan J, Fitzgerald KA. Emerging role of long noncoding RNAs as regulators of innate immune cell development and inflammatory gene expression. Eur J Immunol. 2016 Mar; 46(3):504-12.
Score: 0.292
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Barrat FJ, Elkon KB, Fitzgerald KA. Importance of Nucleic Acid Recognition in Inflammation and Autoimmunity. Annu Rev Med. 2016; 67:323-36.
Score: 0.286
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Carpenter S, Ricci EP, Mercier BC, Moore MJ, Fitzgerald KA. Post-transcriptional regulation of gene expression in innate immunity. Nat Rev Immunol. 2014 Jun; 14(6):361-76.
Score: 0.259
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Carpenter S, Aiello D, Atianand MK, Ricci EP, Gandhi P, Hall LL, Byron M, Monks B, Henry-Bezy M, Lawrence JB, O'Neill LA, Moore MJ, Caffrey DR, Fitzgerald KA. A long noncoding RNA mediates both activation and repression of immune response genes. Science. 2013 Aug 16; 341(6147):789-92.
Score: 0.244
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Atianand MK, Fitzgerald KA. Molecular basis of DNA recognition in the immune system. J Immunol. 2013 Mar 01; 190(5):1911-8.
Score: 0.237
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Fitzgerald KA. NLR-containing inflammasomes: central mediators of host defense and inflammation. Eur J Immunol. 2010 Mar; 40(3):595-8.
Score: 0.193
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Bryant C, Fitzgerald KA. Molecular mechanisms involved in inflammasome activation. Trends Cell Biol. 2009 Sep; 19(9):455-64.
Score: 0.186
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Fitzgerald KA. Integr-ating IL-1 alpha in antiviral host defenses. Immunity. 2009 Jul 17; 31(1):7-9.
Score: 0.185
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Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, Latz E, Fitzgerald KA. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature. 2009 Mar 26; 458(7237):514-8.
Score: 0.179
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Ketelut-Carneiro N, Mathur A, Fitzgerald KA. Licensed to pore: Gasdermins in action. Cell Chem Biol. 2026 Jul 16; 33(7):982-1004.
Score: 0.149
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Miao G, Fortier TM, Liu H, Schafer DP, Fitzgerald KA, Mao J, Baehrecke EH. Microglia promote inflammatory cell death upon neuronal mitochondrial impairment during neurodegeneration. Nat Struct Mol Biol. 2025 Oct; 32(10):2046-2059.
Score: 0.139
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Zhang B, Orning P, Lehman JW, Dinis A, Torres-Ulloa L, Elling R, Kelliher MA, Bertin J, Proulx MK, Goguen JD, Ryan L, Kandasamy RK, Espevik T, Pai AA, Fitzgerald KA, Lien E. Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance. Proc Natl Acad Sci U S A. 2025 Feb 18; 122(7):e2420802122.
Score: 0.136
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Fitzgerald KA, Shmuel-Galia L. Lnc-ing RNA to intestinal homeostasis and inflammation. Trends Immunol. 2024 02; 45(2):127-137.
Score: 0.126
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Shmuel-Galia L, Humphries F, Vierbuchen T, Jiang Z, Santos N, Johnson J, Shklyar B, Joannas L, Mustone N, Sherman S, Ward D, Houghton J, Baer CE, O'Hara A, Henao-Mejia J, Hoebe K, Fitzgerald KA. The lncRNA HOXA11os regulates mitochondrial function in myeloid cells to maintain intestinal homeostasis. Cell Metab. 2023 08 08; 35(8):1441-1456.e9.
Score: 0.122
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Miner JJ, Fitzgerald KA. A path towards personalized medicine for autoinflammatory and related diseases. Nat Rev Rheumatol. 2023 03; 19(3):182-189.
Score: 0.118
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Gao KM, Marshak-Rothstein A, Fitzgerald KA. Type-1 interferon-dependent and -independent mechanisms in cyclic GMP-AMP synthase-stimulator of interferon genes-driven auto-inflammation. Curr Opin Immunol. 2023 02; 80:102280.
Score: 0.118
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Vierbuchen T, Agarwal S, Johnson JL, Galia L, Lei X, Stein K, Olagnier D, Gaede KI, Herzmann C, Holm CK, Heine H, Pai A, O'Hara Hall A, Hoebe K, Fitzgerald KA. The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2. Proc Natl Acad Sci U S A. 2023 01 03; 120(1):e2213715120.
Score: 0.117
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Shmuel-Galia L, Humphries F, Lei X, Ceglia S, Wilson R, Jiang Z, Ketelut-Carneiro N, Foley SE, Pechhold S, Houghton J, Muneeruddin K, Shaffer SA, McCormick BA, Reboldi A, Ward D, Marshak-Rothstein A, Fitzgerald KA. Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells. Immunity. 2021 06 08; 54(6):1137-1153.e8.
Score: 0.105
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Pereira LMN, Assis PA, de Ara?jo NM, Durso DF, Junqueira C, Ata?de MA, Pereira DB, Lien E, Fitzgerald KA, Zamboni DS, Golenbock DT, Gazzinelli RT. Caspase-8 mediates inflammation and disease in rodent malaria. Nat Commun. 2020 09 14; 11(1):4596.
Score: 0.100
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Yang G, Lee HE, Moon SJ, Ko KM, Koh JH, Seok JK, Min JK, Heo TH, Kang HC, Cho YY, Lee HS, Fitzgerald KA, Lee JY. Direct Binding to NLRP3 Pyrin Domain as a Novel Strategy to Prevent NLRP3-Driven Inflammation and Gouty Arthritis. Arthritis Rheumatol. 2020 07; 72(7):1192-1202.
Score: 0.098
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Fitzgerald KA, Kagan JC. Toll-like Receptors and the Control of Immunity. Cell. 2020 03 19; 180(6):1044-1066.
Score: 0.097
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Motwani M, Pesiridis S, Fitzgerald KA. DNA sensing by the cGAS-STING pathway in health and disease. Nat Rev Genet. 2019 11; 20(11):657-674.
Score: 0.093
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Motwani M, Pawaria S, Bernier J, Moses S, Henry K, Fang T, Burkly L, Marshak-Rothstein A, Fitzgerald KA. Hierarchy of clinical manifestations in SAVI N153S and V154M mouse models. Proc Natl Acad Sci U S A. 2019 04 16; 116(16):7941-7950.
Score: 0.090
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Carpenter S, Fitzgerald KA. Cytokines and Long Noncoding RNAs. Cold Spring Harb Perspect Biol. 2018 06 01; 10(6).
Score: 0.085
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O'Donnell JA, Lehman J, Roderick JE, Martinez-Marin D, Zelic M, Doran C, Hermance N, Lyle S, Pasparakis M, Fitzgerald KA, Marshak-Rothstein A, Kelliher MA. Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity. J Immunol. 2018 01 15; 200(2):737-748.
Score: 0.083
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Rathinam VA, Fitzgerald KA. Inflammasome Complexes: Emerging Mechanisms and Effector Functions. Cell. 2016 May 05; 165(4):792-800.
Score: 0.074
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Schattgen SA, Gao G, Kurt-Jones EA, Fitzgerald KA. Cutting Edge: DNA in the Lung Microenvironment during Influenza Virus Infection Tempers Inflammation by Engaging the DNA Sensor AIM2. J Immunol. 2016 Jan 01; 196(1):29-33.
Score: 0.072
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Carpenter S, Fitzgerald KA. Transcription of inflammatory genes: long noncoding RNA and beyond. J Interferon Cytokine Res. 2015 Feb; 35(2):79-88.
Score: 0.066
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Sheedy FJ, Grebe A, Rayner KJ, Kalantari P, Ramkhelawon B, Carpenter SB, Becker CE, Ediriweera HN, Mullick AE, Golenbock DT, Stuart LM, Latz E, Fitzgerald KA, Moore KJ. CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation. Nat Immunol. 2013 Aug; 14(8):812-20.
Score: 0.061
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Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, MacDonald K, Speert D, Fernandes-Alnemri T, Wu J, Monks BG, Fitzgerald KA, Hornung V, Latz E. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol. 2009 Jul 15; 183(2):787-91.
Score: 0.046
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Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, Fitzgerald KA, Latz E, Moore KJ, Golenbock DT. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol. 2008 Aug; 9(8):857-65.
Score: 0.043
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Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, Latz E. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol. 2008 Aug; 9(8):847-56.
Score: 0.043
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Johnson JL, Sargsyan D, Neiman EM, Hart A, Stojmirovic A, Kosoy R, Irizar H, Su?rez-Fari?as M, Song WM, Argmann C, Avey S, Shmuel-Galia L, Vierbuchen T, Bongers G, Sun Y, Edelstein L, Perrigoue J, Towne JE, Hall AO, Fitzgerald KA, Hoebe K. Gene coexpression networks reveal a broad role for lncRNAs in inflammatory bowel disease. JCI Insight. 2024 02 08; 9(3).
Score: 0.032
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MacLauchlan S, Fitzgerald KA, Gravallese EM. Intracellular Sensing of DNA in Autoinflammation and Autoimmunity. Arthritis Rheumatol. 2022 10; 74(10):1615-1624.
Score: 0.029
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Foley SE, Dente MJ, Lei X, Sallis BF, Loew EB, Meza-Segura M, Fitzgerald KA, McCormick BA. Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epithelium That Directs P-Glycoprotein Expression. mBio. 2022 08 30; 13(4):e0199322.
Score: 0.029
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Balic JJ, Albargy H, Luu K, Kirby FJ, Jayasekara WSN, Mansell F, Garama DJ, De Nardo D, Baschuk N, Louis C, Humphries F, Fitzgerald K, Latz E, Gough DJ, Mansell A. STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1? expression. Nat Commun. 2020 07 30; 11(1):3816.
Score: 0.025
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Fitzgerald KA, O'Neill LA. The role of the interleukin-1/Toll-like receptor superfamily in inflammation and host defence. Microbes Infect. 2000 Jul; 2(8):933-43.
Score: 0.025
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Gross-Vered M, Shmuel-Galia L, Zarmi B, Humphries F, Thaiss C, Salame TM, David E, Chappell-Maor L, Fitzgerald KA, Shai Y, Jung S. TLR2 Dimerization Blockade Allows Generation of Homeostatic Intestinal Macrophages under Acute Colitis Challenge. J Immunol. 2020 02 01; 204(3):707-717.
Score: 0.024
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King KR, Aguirre AD, Ye YX, Sun Y, Roh JD, Ng RP, Kohler RH, Arlauckas SP, Iwamoto Y, Savol A, Sadreyev RI, Kelly M, Fitzgibbons TP, Fitzgerald KA, Mitchison T, Libby P, Nahrendorf M, Weissleder R. IRF3 and type I interferons fuel a fatal response to myocardial infarction. Nat Med. 2017 Dec; 23(12):1481-1487.
Score: 0.021
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Pawaria S, Sharma S, Baum R, N?ndel K, Busto P, Gravallese EM, Fitzgerald KA, Marshak-Rothstein A. Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent? J Leukoc Biol. 2017 01; 101(1):121-126.
Score: 0.019
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Ataide MA, Andrade WA, Zamboni DS, Wang D, Souza Mdo C, Franklin BS, Elian S, Martins FS, Pereira D, Reed G, Fitzgerald KA, Golenbock DT, Gazzinelli RT. Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection. PLoS Pathog. 2014 Jan; 10(1):e1003885.
Score: 0.016
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Wang D, H?ing S, Patterson HC, Ahmad UM, Rathinam VA, Rajewsky K, Fitzgerald KA, Golenbock DT. Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins. J Biol Chem. 2013 Feb 15; 288(7):4594-601.
Score: 0.015
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Shi CS, Shenderov K, Huang NN, Kabat J, Abu-Asab M, Fitzgerald KA, Sher A, Kehrl JH. Activation of autophagy by inflammatory signals limits IL-1? production by targeting ubiquitinated inflammasomes for destruction. Nat Immunol. 2012 Jan 29; 13(3):255-63.
Score: 0.014
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Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nu?ez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature. 2010 Apr 29; 464(7293):1357-61.
Score: 0.012
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Cole LE, Laird MH, Seekatz A, Santiago A, Jiang Z, Barry E, Shirey KA, Fitzgerald KA, Vogel SN. Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling. J Leukoc Biol. 2010 Feb; 87(2):275-81.
Score: 0.012
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Balkhi MY, Fitzgerald KA, Pitha PM. IKKalpha negatively regulates IRF-5 function in a MyD88-TRAF6 pathway. Cell Signal. 2010 Jan; 22(1):117-27.
Score: 0.012
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Hise AG, Daehnel K, Gillette-Ferguson I, Cho E, McGarry HF, Taylor MJ, Golenbock DT, Fitzgerald KA, Kazura JW, Pearlman E. Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM. J Immunol. 2007 Jan 15; 178(2):1068-76.
Score: 0.010
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Bj?rkbacka H, Fitzgerald KA, Huet F, Li X, Gregory JA, Lee MA, Ordija CM, Dowley NE, Golenbock DT, Freeman MW. The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades. Physiol Genomics. 2004 Nov 17; 19(3):319-30.
Score: 0.008