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This is a "connection" page, showing publications Leonard Shultz has written about Male.
Leonard Shultz
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Male
  1. Brehm MA, Kenney LL, Wiles MV, Low BE, Tisch RM, Burzenski L, Mueller C, Greiner DL, Shultz LD. Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression. FASEB J. 2019 03; 33(3):3137-3151.
    View in: PubMed
    Score: 0.037
  2. Wilson DW, Oslund KL, Lyons B, Foreman O, Burzenski L, Svenson KL, Chase TH, Shultz LD. Inflammatory dilated cardiomyopathy in Abcg5-deficient mice. Toxicol Pathol. 2013 Aug; 41(6):880-92.
    View in: PubMed
    Score: 0.024
  3. Hosur V, Kavirayani A, Riefler J, Carney LM, Lyons B, Gott B, Cox GA, Shultz LD. Dystrophin and dysferlin double mutant mice: a novel model for rhabdomyosarcoma. Cancer Genet. 2012 May; 205(5):232-41.
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    Score: 0.024
  4. Foreman O, Kavirayani AM, Griffey SM, Reader R, Shultz LD. Opportunistic bacterial infections in breeding colonies of the NSG mouse strain. Vet Pathol. 2011 Mar; 48(2):495-9.
    View in: PubMed
    Score: 0.021
  5. Chase TH, Lyons BL, Bronson RT, Foreman O, Donahue LR, Burzenski LM, Gott B, Lane P, Harris B, Ceglarek U, Thiery J, Wittenburg H, Thon JN, Italiano JE, Johnson KR, Shultz LD. The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia. Blood. 2010 Feb 11; 115(6):1267-76.
    View in: PubMed
    Score: 0.020
  6. Pearson T, Greiner DL, Shultz LD. Creation of "humanized" mice to study human immunity. Curr Protoc Immunol. 2008 May; Chapter 15:15.21.1-15.21.21.
    View in: PubMed
    Score: 0.018
  7. Lyons BL, Smith RS, Hurd RE, Hawes NL, Burzenski LM, Nusinowitz S, Hasham MG, Chang B, Shultz LD. Deficiency of SHP-1 protein-tyrosine phosphatase in "viable motheaten" mice results in retinal degeneration. Invest Ophthalmol Vis Sci. 2006 Mar; 47(3):1201-9.
    View in: PubMed
    Score: 0.015
  8. Ueno M, Lyons BL, Burzenski LM, Gott B, Shaffer DJ, Roopenian DC, Shultz LD. Accelerated wound healing of alkali-burned corneas in MRL mice is associated with a reduced inflammatory signature. Invest Ophthalmol Vis Sci. 2005 Nov; 46(11):4097-106.
    View in: PubMed
    Score: 0.015
  9. Shultz LD, Lyons BL, Burzenski LM, Gott B, Chen X, Chaleff S, Kotb M, Gillies SD, King M, Mangada J, Greiner DL, Handgretinger R. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol. 2005 May 15; 174(10):6477-89.
    View in: PubMed
    Score: 0.015
  10. Coate KC, Dai C, Singh A, Stanley J, Covington BA, Bradley A, Oladipupo F, Gong Y, Wisniewski S, Sellick K, Spears E, Poffenberger G, Schornack AMR, Bustabad A, Rodgers T, Dey N, Shultz LD, Greiner DL, Yan H, Powers AC, Chen W, Dean ED. Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners. Mol Metab. 2024 Dec; 90:102050.
    View in: PubMed
    Score: 0.014
  11. Hasanali ZS, Garfall AL, Burzenski L, Shultz LD, Tang Y, Kadu S, Sheppard NC, Liu W, Dopkin D, Vogl DT, Cohen AD, Waxman AJ, Susanibar-Adaniya SP, Carroll M, Stadtmauer EA, Allman D. Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice. JCI Insight. 2024 May 07; 9(10).
    View in: PubMed
    Score: 0.014
  12. Rajan TV, Ganley L, Paciorkowski N, Spencer L, Klei TR, Shultz LD. Brugian infections in the peritoneal cavities of laboratory mice: kinetics of infection and cellular responses. Exp Parasitol. 2002 Apr; 100(4):235-47.
    View in: PubMed
    Score: 0.012
  13. Joliat MJ, Lang PA, Lyons BL, Burzenski L, Lynes MA, Yi T, Sundberg JP, Shultz LD. Absence of CD5 dramatically reduces progression of pulmonary inflammatory lesions in SHP-1 protein-tyrosine phosphatase-deficient 'viable motheaten' mice. J Autoimmun. 2002 Mar; 18(2):105-17.
    View in: PubMed
    Score: 0.012
  14. Dai C, Walker JT, Shostak A, Bouchi Y, Poffenberger G, Hart NJ, Jacobson DA, Calcutt MW, Bottino R, Greiner DL, Shultz LD, McGuinness OP, Dean ED, Powers AC. Dapagliflozin Does Not Directly Affect Human a or ? Cells. Endocrinology. 2020 08 01; 161(8).
    View in: PubMed
    Score: 0.010
  15. Hosur V, Low BE, Li D, Stafford GA, Kohar V, Shultz LD, Wiles MV. Genes adapt to outsmart gene-targeting strategies in mutant mouse strains by skipping exons to reinitiate transcription and translation. Genome Biol. 2020 07 09; 21(1):168.
    View in: PubMed
    Score: 0.010
  16. Shultz LD, Lang PA, Christianson SW, Gott B, Lyons B, Umeda S, Leiter E, Hesselton R, Wagar EJ, Leif JH, Kollet O, Lapidot T, Greiner DL. NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells. J Immunol. 2000 Mar 01; 164(5):2496-507.
    View in: PubMed
    Score: 0.010
  17. Johanna I, Hern?ndez-L?pez P, Heijhuurs S, Bongiovanni L, de Bruin A, Beringer D, van Dooremalen S, Shultz LD, Ishikawa F, Sebestyen Z, Straetemans T, Kuball J. TEG011 persistence averts extramedullary tumor growth without exerting off-target toxicity against healthy tissues in a humanized HLA-A*24:02 transgenic mice. J Leukoc Biol. 2020 06; 107(6):1069-1079.
    View in: PubMed
    Score: 0.010
  18. Dai C, Walker JT, Shostak A, Padgett A, Spears E, Wisniewski S, Poffenberger G, Aramandla R, Dean ED, Prasad N, Levy SE, Greiner DL, Shultz LD, Bottino R, Powers AC. Tacrolimus- and sirolimus-induced human ? cell dysfunction is reversible and preventable. JCI Insight. 2020 01 16; 5(1).
    View in: PubMed
    Score: 0.010
  19. Redick SD, Leehy L, Rittenhouse AR, Blodgett DM, Derr AG, Kucukural A, Garber MG, Shultz LD, Greiner DL, Wang JP, Harlan DM, Bortell R, Jurczyk A. Recovery of viable endocrine-specific cells and transcriptomes from human pancreatic islet-engrafted mice. FASEB J. 2020 01; 34(1):1901-1911.
    View in: PubMed
    Score: 0.010
  20. Matsuda M, Ono R, Iyoda T, Endo T, Iwasaki M, Tomizawa-Murasawa M, Saito Y, Kaneko A, Shimizu K, Yamada D, Ogonuki N, Watanabe T, Nakayama M, Koseki Y, Kezuka-Shiotani F, Hasegawa T, Yabe H, Kato S, Ogura A, Shultz LD, Ohara O, Taniguchi M, Koseki H, Fujii SI, Ishikawa F. Human NK cell development in hIL-7 and hIL-15 knockin NOD/SCID/IL2rgKO mice. Life Sci Alliance. 2019 04; 2(2).
    View in: PubMed
    Score: 0.010
  21. Bahmani B, Uehara M, Ordikhani F, Li X, Jiang L, Banouni N, Ichimura T, Kasinath V, Eskandari SK, Annabi N, Bromberg JS, Shultz LD, Greiner DL, Abdi R. Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery. EBioMedicine. 2018 Dec; 38:79-88.
    View in: PubMed
    Score: 0.009
  22. Saunders DC, Brissova M, Phillips N, Shrestha S, Walker JT, Aramandla R, Poffenberger G, Flaherty DK, Weller KP, Pelletier J, Cooper T, Goff MT, Virostko J, Shostak A, Dean ED, Greiner DL, Shultz LD, Prasad N, Levy SE, Carnahan RH, Dai C, S?vigny J, Powers AC. Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic ? Cells for In?Vitro and In?Vivo Analysis. Cell Metab. 2019 03 05; 29(3):745-754.e4.
    View in: PubMed
    Score: 0.009
  23. Brissova M, Haliyur R, Saunders D, Shrestha S, Dai C, Blodgett DM, Bottino R, Campbell-Thompson M, Aramandla R, Poffenberger G, Lindner J, Pan FC, von Herrath MG, Greiner DL, Shultz LD, Sanyoura M, Philipson LH, Atkinson M, Harlan DM, Levy SE, Prasad N, Stein R, Powers AC. a Cell Function and Gene Expression Are Compromised in Type 1 Diabetes. Cell Rep. 2018 03 06; 22(10):2667-2676.
    View in: PubMed
    Score: 0.009
  24. Saito Y, Mochizuki Y, Ogahara I, Watanabe T, Hogdal L, Takagi S, Sato K, Kaneko A, Kajita H, Uchida N, Fukami T, Shultz LD, Taniguchi S, Ohara O, Letai AG, Ishikawa F. Overcoming mutational complexity in acute myeloid leukemia by inhibition of critical pathways. Sci Transl Med. 2017 Oct 25; 9(413).
    View in: PubMed
    Score: 0.009
  25. Borel F, Tang Q, Gernoux G, Greer C, Wang Z, Barzel A, Kay MA, Shultz LD, Greiner DL, Flotte TR, Brehm MA, Mueller C. Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of a-1 Antitrypsin Deficiency. Mol Ther. 2017 11 01; 25(11):2477-2489.
    View in: PubMed
    Score: 0.009
  26. Dai C, Hang Y, Shostak A, Poffenberger G, Hart N, Prasad N, Phillips N, Levy SE, Greiner DL, Shultz LD, Bottino R, Kim SK, Powers AC. Age-dependent human ? cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. J Clin Invest. 2017 Oct 02; 127(10):3835-3844.
    View in: PubMed
    Score: 0.009
  27. Miller PH, Rabu G, MacAldaz M, Knapp DJ, Cheung AM, Dhillon K, Nakamichi N, Beer PA, Shultz LD, Humphries RK, Eaves CJ. Analysis of parameters that affect human hematopoietic cell outputs in mutant c-kit-immunodeficient mice. Exp Hematol. 2017 04; 48:41-49.
    View in: PubMed
    Score: 0.008
  28. Sundberg JP, France M, Boggess D, Sundberg BA, Jenson AB, Beamer WG, Shultz LD. Development and progression of psoriasiform dermatitis and systemic lesions in the flaky skin (fsn) mouse mutant. Pathobiology. 1997; 65(5):271-86.
    View in: PubMed
    Score: 0.008
  29. Christianson SW, Greiner DL, Schweitzer IB, Gott B, Beamer GL, Schweitzer PA, Hesselton RM, Shultz LD. Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice. Cell Immunol. 1996 Aug 01; 171(2):186-99.
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    Score: 0.008
  30. Noben-Trauth N, Schweitzer PA, Johnson KR, Wolf SF, Knowles BB, Shultz LD. The interleukin-12 beta subunit (p40) maps to mouse chromosome 11. Mamm Genome. 1996 May; 7(5):392.
    View in: PubMed
    Score: 0.008
  31. Schweitzer PA, Noben-Trauth N, Pelsue SC, Johnson KR, Wolf SF, Shultz LD. Genetic mapping of the IL-12 alpha chain gene (Il12a) on mouse chromosome 3. Mamm Genome. 1996 May; 7(5):394-5.
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    Score: 0.008
  32. Serr I, F?rst RW, Achenbach P, Scherm MG, G?kmen F, Haupt F, Sedlmeier EM, Knopff A, Shultz L, Willis RA, Ziegler AG, Daniel C. Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice. Nat Commun. 2016 Mar 15; 7:10991.
    View in: PubMed
    Score: 0.008
  33. Goel HL, Pursell B, Shultz LD, Greiner DL, Brekken RA, Vander Kooi CW, Mercurio AM. P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer. Cell Rep. 2016 Mar 08; 14(9):2193-2208.
    View in: PubMed
    Score: 0.008
  34. Friedline RH, Ko HJ, Jung DY, Lee Y, Bortell R, Dagdeviren S, Patel PR, Hu X, Inashima K, Kearns C, Tsitsilianos N, Shafiq U, Shultz LD, Lee KW, Greiner DL, Kim JK. Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance. FASEB J. 2016 Mar; 30(3):1328-38.
    View in: PubMed
    Score: 0.008
  35. Pelsue SC, Schweitzer PA, Beamer WG, Shultz LD. Mapping of the flaky skin (fsn) mutation on distal mouse chromosome 17. Mamm Genome. 1995 Oct; 6(10):758.
    View in: PubMed
    Score: 0.007
  36. Shultz LD, Schweitzer PA, Christianson SW, Gott B, Schweitzer IB, Tennent B, McKenna S, Mobraaten L, Rajan TV, Greiner DL, et al. Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice. J Immunol. 1995 Jan 01; 154(1):180-91.
    View in: PubMed
    Score: 0.007
  37. Aoki Y, Watanabe T, Saito Y, Kuroki Y, Hijikata A, Takagi M, Tomizawa D, Eguchi M, Eguchi-Ishimae M, Kaneko A, Ono R, Sato K, Suzuki N, Fujiki S, Koh K, Ishii E, Shultz LD, Ohara O, Mizutani S, Ishikawa F. Identification of CD34+ and CD34- leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemia. Blood. 2015 Feb 05; 125(6):967-80.
    View in: PubMed
    Score: 0.007
  38. Welsh RM, O'Donnell CL, Shultz LD. Antiviral activity of NK 1.1+ natural killer cells in C57BL/6 scid mice infected with murine cytomegalovirus. Nat Immun. 1994 Sep-Oct; 13(5):239-45.
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    Score: 0.007
  39. Maykel J, Liu JH, Li H, Shultz LD, Greiner DL, Houghton J. NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer. Dig Dis Sci. 2014 Jun; 59(6):1169-79.
    View in: PubMed
    Score: 0.007
  40. Potter CS, Wang Z, Silva KA, Kennedy VE, Stearns TM, Burzenski L, Shultz LD, Hogenesch H, Sundberg JP. Chronic proliferative dermatitis in Sharpin null mice: development of an autoinflammatory disease in the absence of B and T lymphocytes and IL4/IL13 signaling. PLoS One. 2014; 9(1):e85666.
    View in: PubMed
    Score: 0.007
  41. Usuda H, Naito M, Umeda S, Takahashi K, Shultz LD. Ultrastructure of macrophages and dendritic cells in osteopetrosis (op) mutant mice lacking macrophage colony-stimulating factor (M-CSF/CSF-1) activity. J Submicrosc Cytol Pathol. 1994 Jan; 26(1):111-9.
    View in: PubMed
    Score: 0.007
  42. Saito Y, Yuki H, Kuratani M, Hashizume Y, Takagi S, Honma T, Tanaka A, Shirouzu M, Mikuni J, Handa N, Ogahara I, Sone A, Najima Y, Tomabechi Y, Wakiyama M, Uchida N, Tomizawa-Murasawa M, Kaneko A, Tanaka S, Suzuki N, Kajita H, Aoki Y, Ohara O, Shultz LD, Fukami T, Goto T, Taniguchi S, Yokoyama S, Ishikawa F. A pyrrolo-pyrimidine derivative targets human primary AML stem cells in vivo. Sci Transl Med. 2013 Apr 17; 5(181):181ra52.
    View in: PubMed
    Score: 0.006
  43. Tanaka T, Fujita Y, Ueno M, Shultz LD, Yamashita T. Suppression of SHP-1 promotes corticospinal tract sprouting and functional recovery after brain injury. Cell Death Dis. 2013 Apr 04; 4:e567.
    View in: PubMed
    Score: 0.006
  44. Hickey RD, Galivo F, Schug J, Brehm MA, Haft A, Wang Y, Benedetti E, Gu G, Magnuson MA, Shultz LD, Lagasse E, Greiner DL, Kaestner KH, Grompe M. Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming. Stem Cell Res. 2013 Jul; 11(1):503-15.
    View in: PubMed
    Score: 0.006
  45. Seymour R, Shirley BJ, Hogenesch H, Shultz LD, Sundberg JP. Loss of function of the mouse Sharpin gene results in Peyer's patch regression. PLoS One. 2013; 8(2):e55224.
    View in: PubMed
    Score: 0.006
  46. Shultz LD, Lane PW, Coman DR, Taylor S, Hall E, Lyons B, Wood BG, Schlager G. Hairpatches, a single gene mutation characterized by progressive renal disease and alopecia in the mouse. A potential model for a newly described heritable human disorder. Lab Invest. 1991 Nov; 65(5):588-600.
    View in: PubMed
    Score: 0.006
  47. Moriceau G, Ory B, Mitrofan L, Riganti C, Blanchard F, Brion R, Charrier C, Battaglia S, Pilet P, Denis MG, Shultz LD, M?nkk?nen J, R?dini F, Heymann D. Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process. Cancer Res. 2010 Dec 15; 70(24):10329-39.
    View in: PubMed
    Score: 0.005
  48. Libby SJ, Brehm MA, Greiner DL, Shultz LD, McClelland M, Smith KD, Cookson BT, Karlinsey JE, Kinkel TL, Porwollik S, Canals R, Cummings LA, Fang FC. Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection. Proc Natl Acad Sci U S A. 2010 Aug 31; 107(35):15589-94.
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    Score: 0.005
  49. Bernstein JM, Brooks SP, Lehman HK, Pope L, Sands A, Shultz LD, Bankert RB. Human nasal polyp microenvironments maintained in a viable and functional state as xenografts in NOD-scid IL2rgamma(null) mice. Ann Otol Rhinol Laryngol. 2009 Dec; 118(12):866-75.
    View in: PubMed
    Score: 0.005
  50. King MA, Covassin L, Brehm MA, Racki W, Pearson T, Leif J, Laning J, Fodor W, Foreman O, Burzenski L, Chase TH, Gott B, Rossini AA, Bortell R, Shultz LD, Greiner DL. Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex. Clin Exp Immunol. 2009 Jul; 157(1):104-18.
    View in: PubMed
    Score: 0.005
  51. Chopra P, Diiorio P, Pino SC, Wilson SB, Phillips NE, Mordes JP, Rossini AA, Greiner DL, Shultz LD, Bortell R. Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat. In Vivo. 2009 Mar-Apr; 23(2):195-201.
    View in: PubMed
    Score: 0.005
  52. Van Zant G, Shultz L. Hematologic abnormalities of the immunodeficient mouse mutant, viable motheaten (mev). Exp Hematol. 1989 Feb; 17(2):81-7.
    View in: PubMed
    Score: 0.005
  53. Giassi LJ, Pearson T, Shultz LD, Laning J, Biber K, Kraus M, Woda BA, Schmidt MR, Woodland RT, Rossini AA, Greiner DL. Expanded CD34+ human umbilical cord blood cells generate multiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice. Exp Biol Med (Maywood). 2008 Aug; 233(8):997-1012.
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    Score: 0.005
  54. Gaines P, Tien CW, Olins AL, Olins DE, Shultz LD, Carney L, Berliner N. Mouse neutrophils lacking lamin B-receptor expression exhibit aberrant development and lack critical functional responses. Exp Hematol. 2008 Aug; 36(8):965-76.
    View in: PubMed
    Score: 0.004
  55. Leiter EH, Prochazka M, Shultz LD. Effect of immunodeficiency on diabetogenesis in genetically diabetic (db/db) mice. J Immunol. 1987 May 15; 138(10):3224-9.
    View in: PubMed
    Score: 0.004
  56. Yoshino M, Yamazaki H, Shultz LD, Hayashi S. Constant rate of steady-state self-antigen trafficking from skin to regional lymph nodes. Int Immunol. 2006 Nov; 18(11):1541-8.
    View in: PubMed
    Score: 0.004
  57. Jaeschke A, Rinc?n M, Doran B, Reilly J, Neuberg D, Greiner DL, Shultz LD, Rossini AA, Flavell RA, Davis RJ. Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes. Proc Natl Acad Sci U S A. 2005 May 10; 102(19):6931-5.
    View in: PubMed
    Score: 0.004
  58. Gordon EJ, Wicker LS, Peterson LB, Serreze DV, Markees TG, Shultz LD, Rossini AA, Greiner DL, Mordes JP. Autoimmune diabetes and resistance to xenograft transplantation tolerance in NOD mice. Diabetes. 2005 Jan; 54(1):107-15.
    View in: PubMed
    Score: 0.004
  59. Shultz LD, Coman DR, Bailey CL, Beamer WG, Sidman CL. "Viable motheaten," a new allele at the motheaten locus. I. Pathology. Am J Pathol. 1984 Aug; 116(2):179-92.
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    Score: 0.003
  60. Kuzin II, Ugine GD, Barth RK, Shultz LD, Nahm MH, Young FM, Bottaro A. A new murine model of humoral immuno-deficiency specifically affects class switching to T-independent antigens. Eur J Immunol. 2004 Jul; 34(7):1807-16.
    View in: PubMed
    Score: 0.003
  61. Turgeon NA, Banuelos SJ, Shultz LD, Lyons BL, Iwakoshi N, Greiner DL, Mordes JP, Rossini AA, Appel MC. Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice. Exp Biol Med (Maywood). 2003 Oct; 228(9):1096-104.
    View in: PubMed
    Score: 0.003
  62. Shultz LD, Bailey CL, Coman DR. Hematopoietic stem cell function in motheaten mice. Exp Hematol. 1983 Aug; 11(7):667-80.
    View in: PubMed
    Score: 0.003
  63. Pearson T, Markees TG, Serreze DV, Pierce MA, Marron MP, Wicker LS, Peterson LB, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice. J Immunol. 2003 Jul 01; 171(1):185-95.
    View in: PubMed
    Score: 0.003
  64. Paciorkowski N, Shultz LD, Rajan TV. Primed peritoneal B lymphocytes are sufficient to transfer protection against Brugia pahangi infection in mice. Infect Immun. 2003 Mar; 71(3):1370-8.
    View in: PubMed
    Score: 0.003
  65. Leiter EH, Beamer WG, Shultz LD. The effect of immunosuppression on streptozotocin-induced diabetes in C57BL/KsJ mice. Diabetes. 1983 Feb; 32(2):148-55.
    View in: PubMed
    Score: 0.003
  66. Dell'Agnola C, Rabascio C, Mancuso P, Capillo M, Pruneri G, Gobbi A, Minucci S, Ronzoni S, Volorio S, Calabrese L, Tradati N, Martinelli G, Shultz L, Bertolini F. In vitro and in vivo hematopoietic potential of human stem cells residing in muscle tissue. Exp Hematol. 2002 Aug; 30(8):905-14.
    View in: PubMed
    Score: 0.003
  67. Hoffmann K, Dreger CK, Olins AL, Olins DE, Shultz LD, Lucke B, Karl H, Kaps R, M?ller D, Vay? A, Aznar J, Ware RE, Sotelo Cruz N, Lindner TH, Herrmann H, Reis A, Sperling K. Mutations in the gene encoding the lamin B receptor produce an altered nuclear morphology in granulocytes (Pelger-Hu?t anomaly). Nat Genet. 2002 Aug; 31(4):410-4.
    View in: PubMed
    Score: 0.003
  68. Grzanna R, Shultz LD. The contribution of mast cells to the histamine content of the central nervous system: a regional analysis. Life Sci. 1982 Jun 07; 30(23):1959-64.
    View in: PubMed
    Score: 0.003
  69. Shultz LD, Sweet HO, Davisson MT, Coman DR. 'Wasted', a new mutant of the mouse with abnormalities characteristic to ataxia telangiectasia. Nature. 1982 Jun 03; 297(5865):402-4.
    View in: PubMed
    Score: 0.003
  70. Ballen KK, Valinski H, Greiner D, Shultz LD, Becker PS, Hsieh CC, Stewart FM, Quesenberry PJ. Variables to predict engraftment of umbilical cord blood into immunodeficient mice: usefulness of the non-obese diabetic--severe combined immunodeficient assay. Br J Haematol. 2001 Jul; 114(1):211-8.
    View in: PubMed
    Score: 0.003
  71. Taguchi N, Hashimoto Y, Hsu T, Ansari AA, Shultz L, Dorshkind K, Ikehara S, Naiki M, Gershwin ME. B cells are selectively associated with thymic cortical but not medullary pathology in NZB mice. J Autoimmun. 2001 Jun; 16(4):393-400.
    View in: PubMed
    Score: 0.003
  72. Taguchi N, Ansari A, Hsu T, Hashimoto Y, Dorshkind K, Shultz L, Naiki M, Gershwin ME. Increased expression of mXBP-1 (TREB-5) in thymic B cells in New Zealand mice. J Autoimmun. 2001 Jun; 16(4):401-10.
    View in: PubMed
    Score: 0.003
  73. Nguyen VT, Ndoye A, Bassler KD, Shultz LD, Shields MC, Ruben BS, Webber RJ, Pittelkow MR, Lynch PJ, Grando SA. Classification, clinical manifestations, and immunopathological mechanisms of the epithelial variant of paraneoplastic autoimmune multiorgan syndrome: a reappraisal of paraneoplastic pemphigus. Arch Dermatol. 2001 Feb; 137(2):193-206.
    View in: PubMed
    Score: 0.003
  74. Hamelmann E, Takeda K, Haczku A, Cieslewicz G, Shultz L, Hamid Q, Xing Z, Gauldie J, Gelfand EW. Interleukin (IL)-5 but not immunoglobulin E reconstitutes airway inflammation and airway hyperresponsiveness in IL-4-deficient mice. Am J Respir Cell Mol Biol. 2000 Sep; 23(3):327-34.
    View in: PubMed
    Score: 0.003
  75. Sundberg JP, Boggess D, Bascom C, Limberg BJ, Shultz LD, Sundberg BA, King LE, Montagutelli X. Lanceolate hair-J (lahJ): a mouse model for human hair disorders. Exp Dermatol. 2000 Jun; 9(3):206-18.
    View in: PubMed
    Score: 0.003
  76. Taguchi N, Hashimoto Y, Naiki M, Farr AG, Boyd RL, Ansari AA, Shultz LD, Kotzin BL, Dorshkind K, Ikehara S, Gershwin ME. Abnormal thymic expression of epithelial cell adhesion molecule (EP-CAM) in New Zealand Black (NZB) mice. J Autoimmun. 1999 Dec; 13(4):393-404.
    View in: PubMed
    Score: 0.002
  77. Takeoka Y, Taguchi N, Shultz L, Boyd RL, Naiki M, Ansari AA, Gershwin ME. Apoptosis and the thymic microenvironment in murine lupus. J Autoimmun. 1999 Nov; 13(3):325-34.
    View in: PubMed
    Score: 0.002
  78. Markees TG, Serreze DV, Phillips NE, Sorli CH, Gordon EJ, Shultz LD, Noelle RJ, Woda BA, Greiner DL, Mordes JP, Rossini AA. NOD mice have a generalized defect in their response to transplantation tolerance induction. Diabetes. 1999 May; 48(5):967-74.
    View in: PubMed
    Score: 0.002
  79. Myint YY, Miyakawa K, Naito M, Shultz LD, Oike Y, Yamamura K, Takahashi K. Granulocyte/macrophage colony-stimulating factor and interleukin-3 correct osteopetrosis in mice with osteopetrosis mutation. Am J Pathol. 1999 Feb; 154(2):553-66.
    View in: PubMed
    Score: 0.002
  80. Miyamoto A, Kunisada T, Yamazaki H, Miyake K, Nishikawa SI, Sudo T, Shultz LD, Hayashi SI. Establishment and characterization of pro-B cell lines from motheaten mutant mouse defective in SHP-1 protein tyrosine phosphatase. Immunol Lett. 1998 Sep; 63(2):75-82.
    View in: PubMed
    Score: 0.002
  81. Babu S, Porte P, Klei TR, Shultz LD, Rajan TV. Host NK cells are required for the growth of the human filarial parasite Brugia malayi in mice. J Immunol. 1998 Aug 01; 161(3):1428-32.
    View in: PubMed
    Score: 0.002
  82. Vu TN, Lee TX, Ndoye A, Shultz LD, Pittelkow MR, Dahl MV, Lynch PJ, Grando SA. The pathophysiological significance of nondesmoglein targets of pemphigus autoimmunity. Development of antibodies against keratinocyte cholinergic receptors in patients with pemphigus vulgaris and pemphigus foliaceus. Arch Dermatol. 1998 Aug; 134(8):971-80.
    View in: PubMed
    Score: 0.002
  83. Markees TG, Phillips NE, Gordon EJ, Noelle RJ, Shultz LD, Mordes JP, Greiner DL, Rossini AA. Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4. J Clin Invest. 1998 Jun 01; 101(11):2446-55.
    View in: PubMed
    Score: 0.002
  84. Markees TG, Phillips NE, Noelle RJ, Shultz LD, Mordes JP, Greiner DL, Rossini AA. Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand. Transplantation. 1997 Jul 27; 64(2):329-35.
    View in: PubMed
    Score: 0.002
  85. Cashman JD, Lapidot T, Wang JC, Doedens M, Shultz LD, Lansdorp P, Dick JE, Eaves CJ. Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice. Blood. 1997 Jun 15; 89(12):4307-16.
    View in: PubMed
    Score: 0.002
  86. Yoshida H, Hayashi S, Shultz LD, Yamamura K, Nishikawa S, Nishikawa S, Kunisada T. Neural and skin cell-specific expression pattern conferred by steel factor regulatory sequence in transgenic mice. Dev Dyn. 1996 Oct; 207(2):222-32.
    View in: PubMed
    Score: 0.002
  87. Heine D, Passmore HC, Patel V, Shultz LD, Ward-Bailey P, Cook SA, Davisson MT. Effect of the mouse scid mutation on meiotic recombination. Mamm Genome. 1996 Jul; 7(7):497-500.
    View in: PubMed
    Score: 0.002
  88. Zhong RK, Donnenberg AD, Shultz LD, Swerdlow SH, Lee E, Rubin J, Kozii R, Chen J, Griffin DL, Wilson J, Ball ED. Evaluation of monoclonal antibody-mediated anti-acute myeloid leukemia immunotherapy in a SCID/hu model. Leuk Res. 1996 Jul; 20(7):581-9.
    View in: PubMed
    Score: 0.002
  89. Blazar BR, Brennan CA, Broxmeyer HE, Shultz LD, Vallera DA. Transgenic mice expressing either bovine growth hormone (bGH) or human GH releasing hormone (hGRH) have increased splenic progenitor cell colony formation and DNA synthesis in vitro and in vivo. Exp Hematol. 1995 Dec; 23(13):1397-406.
    View in: PubMed
    Score: 0.002
  90. Serreze DV, Leiter EH, Hanson MS, Christianson SW, Shultz LD, Hesselton RM, Greiner DL. Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells. Diabetes. 1995 Dec; 44(12):1392-8.
    View in: PubMed
    Score: 0.002
  91. Beamer WG, Pelsue SC, Shultz LD, Sundberg JP, Barker JE. The flaky skin (fsn) mutation in mice: map location and description of the anemia. Blood. 1995 Oct 15; 86(8):3220-6.
    View in: PubMed
    Score: 0.002
  92. Green MC, Shultz LD. Motheaten, an immunodeficient mutant of the mouse. I. Genetics and pathology. J Hered. 1975 Sep-Oct; 66(5):250-8.
    View in: PubMed
    Score: 0.002
  93. Rohane PW, Shimada A, Kim DT, Edwards CT, Charlton B, Shultz LD, Fathman CG. Islet-infiltrating lymphocytes from prediabetic NOD mice rapidly transfer diabetes to NOD-scid/scid mice. Diabetes. 1995 May; 44(5):550-4.
    View in: PubMed
    Score: 0.002
  94. Greiner DL, Shultz LD, Yates J, Appel MC, Perdrizet G, Hesselton RM, Schweitzer I, Beamer WG, Shultz KL, Pelsue SC, et al. Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice. Am J Pathol. 1995 Apr; 146(4):888-902.
    View in: PubMed
    Score: 0.002
  95. Rajan TV, Bailis JM, Yates JA, Shultz LD, Greiner DL, Nelson FK. Maternal influence on susceptibility of offspring to Brugia malayi infection in a murine model of filariasis. Acta Trop. 1994 Dec; 58(3-4):283-9.
    View in: PubMed
    Score: 0.002
  96. Rajan TV, Nelson FK, Killeen N, Shultz LD, Yates JA, Bailis JM, Littman DR, Greiner DL. CD4+ T-lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi. Exp Parasitol. 1994 Jun; 78(4):352-60.
    View in: PubMed
    Score: 0.002
  97. Takahashi K, Umeda S, Shultz LD, Hayashi S, Nishikawa S. Effects of macrophage colony-stimulating factor (M-CSF) on the development, differentiation, and maturation of marginal metallophilic macrophages and marginal zone macrophages in the spleen of osteopetrosis (op) mutant mice lacking functional M-CSF activity. J Leukoc Biol. 1994 May; 55(5):581-8.
    View in: PubMed
    Score: 0.002
  98. Rajan TV, Nelson FK, Shultz LD, Shultz KL, Beamer WG, Yates J, Greiner DL. Influence of gonadal steroids on susceptibility to Brugia malayi in scid mice. Acta Trop. 1994 Apr; 56(4):307-14.
    View in: PubMed
    Score: 0.002
  99. Gerling IC, Friedman H, Greiner DL, Shultz LD, Leiter EH. Multiple low-dose streptozocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes. Diabetes. 1994 Mar; 43(3):433-40.
    View in: PubMed
    Score: 0.002
  100. Szomolanyi-Tsuda E, Dundon PL, Joris I, Shultz LD, Woda BA, Welsh RM. Acute, lethal, natural killer cell-resistant myeloproliferative disease induced by polyomavirus in severe combined immunodeficient mice. Am J Pathol. 1994 Feb; 144(2):359-71.
    View in: PubMed
    Score: 0.002
  101. Kapasi ZF, Kosco-Vilbois MH, Shultz LD, Tew JG, Szakal AK. Cellular origin of follicular dendritic cells. Adv Exp Med Biol. 1994; 355:231-5.
    View in: PubMed
    Score: 0.002
  102. Kapasi ZF, Burton GF, Shultz LD, Tew JG, Szakal AK. Induction of functional follicular dendritic cell development in severe combined immunodeficiency mice. Influence of B and T cells. J Immunol. 1993 Apr 01; 150(7):2648-58.
    View in: PubMed
    Score: 0.002
  103. Kapasi ZF, Burton GF, Shultz LD, Tew JG, Szakal AK. Cellular requirements for functional reconstitution of follicular dendritic cells in SCID mice. Adv Exp Med Biol. 1993; 329:383-6.
    View in: PubMed
    Score: 0.002
  104. Takahashi K, Naito M, Shultz LD, Hayashi S, Nishikawa S. Differentiation of dendritic cell populations in macrophage colony-stimulating factor-deficient mice homozygous for the osteopetrosis (op) mutation. J Leukoc Biol. 1993 Jan; 53(1):19-28.
    View in: PubMed
    Score: 0.002
  105. Prochazka M, Gaskins HR, Shultz LD, Leiter EH. The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency. Proc Natl Acad Sci U S A. 1992 Apr 15; 89(8):3290-4.
    View in: PubMed
    Score: 0.001
  106. Ohara A, Anklesaria P, Shultz L, Greenberger JS. Isolation of permanent clonal bone marrow stromal cell lines derived from "viable moth-eaten" and "severe combined immunodeficiency" mutant mice. Int J Cell Cloning. 1992 Jan; 10(1):33-46.
    View in: PubMed
    Score: 0.001
  107. Hagiya M, Davis DD, Shultz LD, Sakano H. Non-germ-line elements (NGE) are present in the T cell receptor beta-chain genes isolated from the mutant mouse, motheaten (me/me). J Immunol. 1986 Apr 01; 136(7):2697-700.
    View in: PubMed
    Score: 0.001
  108. Sidman CL, Shultz LD, Unanue ER. The mouse mutant "motheaten." II. Functional studies of the immune system. J Immunol. 1978 Dec; 121(6):2399-404.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.